WO2023246407A1 - 贴片产品加工***及贴片产品加工方法 - Google Patents

贴片产品加工***及贴片产品加工方法 Download PDF

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Publication number
WO2023246407A1
WO2023246407A1 PCT/CN2023/095936 CN2023095936W WO2023246407A1 WO 2023246407 A1 WO2023246407 A1 WO 2023246407A1 CN 2023095936 W CN2023095936 W CN 2023095936W WO 2023246407 A1 WO2023246407 A1 WO 2023246407A1
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WO
WIPO (PCT)
Prior art keywords
station
processing line
pressing
target
patch
Prior art date
Application number
PCT/CN2023/095936
Other languages
English (en)
French (fr)
Inventor
黄远
陈宾文
颜平
刘龙
曲秋羽
Original Assignee
苏州悦肤达医疗科技有限公司
上海悦肤达生物科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202210713405.4A external-priority patent/CN117301197A/zh
Priority claimed from CN202221571943.6U external-priority patent/CN217648522U/zh
Application filed by 苏州悦肤达医疗科技有限公司, 上海悦肤达生物科技有限公司 filed Critical 苏州悦肤达医疗科技有限公司
Publication of WO2023246407A1 publication Critical patent/WO2023246407A1/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26F—PERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
    • B26F1/00—Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
    • B26F1/38—Cutting-out; Stamping-out

Definitions

  • the invention belongs to the technical field of patch product processing, and particularly relates to a patch product processing system and a patch product processing method.
  • Microneedles including micron-sized needles loaded with drugs and administered transdermally are one of the ways to solve the above problems.
  • microneedle penetration into the skin usually does not reach the dermis and does not cause obvious pain.
  • intradermal drug delivery with nano-microneedle has the advantages of reducing toxic side effects, improving drug efficacy, and accelerating drug absorption. It is a convenient, minimally painful, safe product that can be used at home.
  • microneedling can also be used as a skin pre-treatment, with the ability to enhance skin permeability. Therefore, microneedles have good clinical application prospects.
  • microneedle patch itself is not sticky and needs to be attached to a sticky material for use. Therefore, the production of microneedle patches includes cutting, laminating, peeling and packaging processes.
  • the current production of microneedle patches is mainly manual production or semi-automatic and semi-manual production. These production methods still have problems such as the inability to produce continuous large quantities, low processing efficiency, complex structures, and the inability to recycle waste materials.
  • the production of other patch products also has basically the same problems, such as silicone sheets, facial masks and other patch-type medical beauty products.
  • the object of the present invention is to provide a patch product processing system and patch product processing method that can realize continuous and large-volume automated production of medical patch products, improve the processing stability and processing efficiency of medical patch products, and reduce Processing costs.
  • the present invention provides a chip product processing system, which includes a first processing line, a second processing line, a third processing line and a fourth processing line; the first processing line, the second processing line The processing line and the third processing line run in parallel; the fourth processing line runs in series with respect to the first processing line, the second processing line and the third processing line; the first processing line It is used to process the original piece of the target object into a target object patch with a predetermined structure; the second processing line is used to process the first-level release paper into a second-level release paper with hollows; the third processing line The line is used to process the primary adhesive tape into a secondary adhesive tape with a predetermined structure; the second processing line is also used to join the secondary adhesive tape with the secondary release paper to obtain A first-level adhesive tape; the fourth processing line is used to join the target patch with the first-level adhesive tape, the target patch is placed in the hollow, and the One side of the target patch is bonded to the secondary adhesive tape.
  • the fourth processing line is first configured to first join the target patch with the first-level adhesive tape to obtain an intermediate product, and then cut the intermediate product to form a plurality of A target product with a predetermined structure;
  • the target product is composed of the second-level adhesive tape, the third-level release paper and the target patch;
  • the third-level release paper is formed by cutting the second-level release paper , the middle part of the third-level release paper has the hollow, the edge of the third-level release paper extends beyond the edge of the second-level adhesive tape, and the second-level adhesive tape is arranged along the edge of the hollow .
  • the first processing line includes a first supporting material belt, a first die-cutting mechanism, a first peeling mechanism, a first waste collecting mechanism and a second waste collecting mechanism.
  • the first supporting material The belt can move from the upstream to the downstream direction of the first processing line; the first processing line is provided with a loading station, a die-cutting station, a first waste collection station, a peeling station and a stripping station in sequence from upstream to downstream.
  • the first supporting material strip is joined to the original piece of the target object at the loading station;
  • the first die-cutting mechanism is provided with a first die at the die-cutting station Cutting support roller and first cutting knife, the first die-cutting support roller and the first cutting knife are respectively located on two opposite sides of the first supporting material belt, and the first cutting knife is used to cut the
  • the target object original piece is used to form the target object patch;
  • the first waste collection mechanism collects the waste material formed after the target object original piece is cut at the first waste collection station;
  • the first peeling mechanism The peeling station is provided with a first peeling knife, and the first peeling knife is arranged on a side of the first backing tape away from the target patch; the first peeling knife passes through its two adjacent The edge of the first support material belt is pressed against the first support material belt, so that the first support material belt changes from the initial horizontal extension direction to the oblique downward extension direction at the first peeling knife to peel off the target object.
  • the first processing line has at least one of the following characteristics:
  • the first waste collection mechanism is provided with a first waste collection support roller and a first waste collection pressure roller at the first waste collection station.
  • a waste collection support roller and the first waste collection pressure roller are respectively located on two opposite sides of the first supporting material belt.
  • the first waste collection mechanism is also provided with a waste discharge tape, a feeding reel and a discharge reel. drum, the feeding drum, the first waste collecting pressure roller and the discharging drum are connected in turn through the waste discharging tape, and the waste discharging tape is sent out from the feeding drum and passes through the third
  • the waste material is bonded after being pressed by a waste collection pressure roller, and the waste discharge tape bonding the waste material is recovered by the discharge drum;
  • the second waste collection mechanism is provided with a first waste collection drum winding the first bottoming material strip at the second waste collection station;
  • the first processing line also includes a first pressing mechanism capable of tensioning the first backing material strip.
  • the first processing line is also provided with a pressing station, and the pressing station is located on the Upstream of the loading station, the first pressing mechanism is provided with a first pressing support roller and a first pressing roller at the pressing station.
  • the first pressing support roller and the first pressing roller The pressing rollers are respectively located on two opposite sides of the first supporting material belt; and,
  • the first processing line also includes a first support strip material roll located at the most upstream, and the first support strip material roll is provided with a roll of first support strip.
  • the first processing line further includes an auxiliary laminating mechanism for laminating the original piece of the target object to the first supporting tape.
  • the first processing line is also provided with Auxiliary laminating station, the auxiliary laminating station is located between the loading station and the die-cutting station, the first supporting material belt is transported from below the loading platform, and is Pass from bottom to top between the discharge side of the loading platform and the auxiliary laminating mechanism.
  • the auxiliary fitting mechanism is configured with at least one of the following features:
  • the auxiliary laminating mechanism includes a first auxiliary laminating mechanism, and the first auxiliary laminating mechanism includes pressing plates and laminating plates located on two opposite sides of the first base material belt; the pressing plates can be close to or away from each other.
  • the laminating plate when the pressing plate is close to the laminating plate, can press against the edge of the original piece of the target object, so that the edge of the original piece of the target object is laminated with the first supporting material strip;
  • the auxiliary bonding mechanism includes a first blowing mechanism for blowing air to the original piece of the target object so that the original piece of the target object is bonded to the first supporting tape; and,
  • the auxiliary laminating mechanism includes a second auxiliary laminating mechanism, and the second auxiliary laminating mechanism includes a first auxiliary laminating pressure roller and a first auxiliary laminating roller located on two opposite sides of the first supporting material belt.
  • Support roller, the first auxiliary laminating pressure roller can be close to or away from the first auxiliary laminating support roller, and the first auxiliary laminating pressure roller can press against the first auxiliary laminating support roller when it is close to the first auxiliary laminating support roller.
  • the edge of the original piece of the target object is bonded to the first supporting material belt, and the roller surface of the first auxiliary bonding pressure roller is wrapped with a protective material.
  • the first processing line includes a loading platform for placing the original pieces of the target object, the loading platform can adsorb the original pieces of the target object, and/or the loading platform It can move and/or rotate itself to push a part of the original piece of the target object out of the loading platform.
  • the loading platform is provided with a plurality of adsorption holes, and a negative pressure chamber connected to the adsorption holes is formed inside the loading platform, wherein the loading platform has the following characteristics: at least one of:
  • a plurality of the adsorption pores are distributed from dense to sparse or from sparse to dense along the discharging direction of the target original piece;
  • a plurality of the adsorption holes are distributed from dense to sparse or from sparse to dense along the discharging direction perpendicular to the original piece of the target object;
  • the distribution density of the plurality of adsorption pores is sparse in the middle and dense at the edges or dense in the middle and sparse at the edges;
  • the pore diameters of the plurality of adsorption pores are distributed from large to small or from small to large along the discharging direction of the target original piece;
  • the pore diameters of the plurality of adsorption holes are distributed from large to small or from small to large along the discharging direction perpendicular to the original piece of the target object;
  • the pore diameters of the plurality of adsorption pores are as follows: the pore diameter is large in the middle part and the pore diameter is small in the edge part; or the pore diameter is small in the middle part and the pore diameter is large in the edge part.
  • the loading platform forms multiple rows of adsorption structures along the discharging direction of the target original piece, and each row of the adsorption structures includes a plurality of the adsorption structures arranged in sequence perpendicular to the discharging direction.
  • Adsorption holes, multiple rows of the adsorption structures form a multi-row and multi-column matrix; some of the adsorption pores in adjacent rows do not share the same negative pressure chamber, and/or some of the adsorption pores in adjacent columns do not share the same negative pressure cavity. The same negative pressure chamber.
  • the loading platform is provided with a plurality of independently provided negative pressure chambers, and the negative pressure chambers are provided with one of the following characteristics:
  • a plurality of the negative pressure cavities are arranged sequentially along the discharging direction of the target original piece
  • a plurality of the negative pressure cavities are arranged sequentially along the discharging direction perpendicular to the target original piece;
  • Some of the plurality of negative pressure cavities are distributed in the middle of the loading platform, and others are distributed on the edges of the loading platform.
  • the loading platform is a profiling conveyor belt.
  • the profiling conveyor belt is provided with a plurality of partitions in sequence along the conveying direction. There is a transmission section between adjacent partitions. Each of the conveyor belts is The segment is used to place an original piece of the target object.
  • the first processing line further includes an auxiliary laminating mechanism for attaching the target original piece to the third A backing material belt is bonded together, and the first backing material belt is used to transport the original piece of the target object;
  • the first processing line is also equipped with an auxiliary bonding station, and the auxiliary bonding station is equipped with Between the loading station and the die-cutting station; the first supporting material belt is transported from below the profiling conveyor belt and passes through the discharge side of the profiling conveyor belt from bottom to top. and the auxiliary laminating mechanism; wherein the height of each partition protruding from the transmission surface of the contoured conveyor belt is less than the gap width between the discharge side of the loading platform and the auxiliary laminating mechanism.
  • a limiting baffle is provided on the loading platform, and the limiting baffle is used to prevent the target original piece from moving in a direction other than the discharging direction.
  • the size of the limiting baffle is adjustable, and/or at least part of the structure of the limiting baffle can be moved relative to the loading platform to move the original piece of the target object. One part is pushed out of the loading platform.
  • the limiting baffle includes two side baffles and a push plate.
  • the two side baffles are arranged on two opposite sides of the push plate.
  • the push plate is connected to the two push plates.
  • the side baffles are movably connected, or the limiting baffle is an integrated curved push plate that surrounds and is used to push the target original piece.
  • the second processing line includes a second supporting material belt, a second pressing mechanism, a second die-cutting mechanism, a third pressing mechanism and a third waste collection mechanism.
  • the material belt is used to move from the upstream to the downstream direction of the second processing line;
  • the second processing line is provided with a first pressing station, a die-cutting station, a second pressing station and a Waste collection station;
  • the second pressing mechanism is provided with a second pressing support roller and a second pressing roller at the first pressing station, and the second pressing support roller and the second The pressing rollers are respectively located on two opposite sides of the second supporting material belt, so that the second supporting material belt and the first-level release paper are joined together;
  • the second die-cutting mechanism is on the The die-cutting station is provided with a second die-cutting support roller and a second cutter.
  • the second die-cutting support roller and the second cutter are respectively located on two opposite sides of the second supporting material belt.
  • the second cutter is used to cut the primary release paper to form the secondary release paper;
  • the third pressing mechanism is provided with a third pressing roller at the second pressing station, so The third pressing roller is provided on one side of the second backing material belt to join the secondary release paper and the secondary adhesive tape;
  • the third waste collection mechanism is on the The waste collection station recycles the first-level release paper through the second support material belt after being cut to form waste material corresponding to the hollow, and makes the second support material belt press the second pressure
  • the closing station is separated from the secondary release paper.
  • the second processing line has at least one of the following characteristics:
  • the third waste collection mechanism is provided with a second waste collection drum winding the second bottoming material strip at the waste collection station;
  • the second processing line also includes a second backing tape material roll and a first-level release paper material roll located at the most upstream, and the second backing tape material roll is provided with a roll of second backing material.
  • the first-level release paper material roll is provided with a roll of first-level release paper, and the second backing tape material roll and the first-level release paper material roll are arranged independently of each other.
  • the third processing line includes a third backing material strip, a fourth pressing mechanism, a third die-cutting mechanism, a fourth scrap collection mechanism, and a fifth pressing mechanism.
  • the material belt is used to move from the upstream to the downstream direction of the third processing line;
  • the third processing line is provided with a first pressing station, a die-cutting station and a scrap collection station in sequence from upstream to downstream.
  • the third processing line is also provided with a second pressing station.
  • the second The pressing station is located downstream of the die-cutting station and parallel to the waste collection station;
  • the fourth pressing mechanism is provided with a fourth pressing support roller and a fourth pressing roller at the first pressing station.
  • the fourth pressing support roller and the fourth pressing roller are respectively Located on two opposite sides of the third backing material strip, so that the third backing material strip is joined to the first-level adhesive tape;
  • the third die-cutting mechanism is provided with a third die-cutting support roller and a third cutter at the die-cutting station.
  • the third die-cutting support roller and the third cutter are respectively located on the third support.
  • the third cutter is used to cut the first-level adhesive tape to form the second-level adhesive tape;
  • the fourth waste collection mechanism recovers the waste material formed by cutting the first-level sticky tape at the waste collection station
  • the fifth pressing mechanism is provided with a fifth pressing support roller at the second pressing station, and the fifth pressing support roller is provided on one side of the third supporting material belt so that the The secondary release paper is combined with the secondary adhesive tape.
  • the third pressing mechanism is provided with a third pressing roller at the second pressing station of the second processing line, and the third pressing roller is provided on the second support.
  • the fifth pressing support roller is located on the other side of the second base material belt, and the third pressing roller and the fifth pressing support roller are located at the same position.
  • the second supporting material belt and the third supporting material belt of the second processing line pass between the third pressing roller and the fifth pressing support roller, and the The fourth processing line and the third processing line share the third supporting material belt.
  • the third supporting material belt continues from the second pressing station of the third processing line to the The fourth processing line conveys.
  • the third processing line further includes a first-level adhesive tape material roll and a third backing tape material roll located at the most upstream, and the third backing tape material roll is provided with a roll.
  • the third backing material tape, the first-level adhesive tape material roll is provided with a roll of first-level adhesive tape, and the third backing material tape material roll and the first-level adhesive tape material roll are arranged independently of each other.
  • the fourth processing line includes a third backing strip, a peeling support mechanism, a laminating mechanism, a fourth die-cutting mechanism, a fifth waste collection mechanism, a second peeling mechanism, and a sixth waste collection mechanism.
  • the third supporting material belt is used to move from the upstream to the downstream direction of the fourth processing line; the fourth processing line is provided with a laminating station, a die-cutting station and a first station in sequence from upstream to downstream.
  • a waste collection station; the fourth processing line is also provided with a stripping station, a second waste collection station and a packaging station; the stripping station is located downstream of the die-cutting station and connected with the third A waste collection station is arranged in parallel; the second waste collection station and the packaging station are both located downstream of the stripping station and arranged in parallel; the stripping support mechanism is located between the laminating station and the A peeling support roller is provided on one side of the third backing material belt; the laminating mechanism applies force to the target patch at the laminating station, so that the target patch and the The first-level adhesive tape is joined; the fourth die-cutting mechanism is provided with a fourth die-cutting support roller and a fourth cutting knife at the die-cutting station.
  • the fourth die-cutting support roller and the fourth cutting knife The knives are respectively located on two opposite sides of the third supporting material belt, and the fourth cutting knife is used to cut the secondary release paper to form a plurality of the target products;
  • the fifth waste collection mechanism is located on the The first waste collection station recycles the waste material formed after the secondary release paper is cut;
  • the second peeling mechanism is provided with a second peeling knife at the peeling station, and the second peeling knife is arranged at the The side of the third supporting material belt facing away from the target product; the second peeling knife resists the third supporting material belt through its two adjacent sides, so that the third supporting material belt is positioned at the desired position.
  • the second peeling knife changes from the initial horizontal extension direction to the oblique upward extension direction to peel off the target product and the third supporting material strip; the sixth waste collection mechanism is in the second waste collection
  • the work station recycles the third supporting material strip; the packaging station is arranged close to the stripping station, and the packaging station is provided with a packaging box, and the target product after stripping automatically falls into the packaging box.
  • the laminating mechanism includes a peeling and laminating pressure roller corresponding to the position of the peeling support roller, and the peeling and laminating pressure roller and the peeling support roller are provided on the third supporting material.
  • the peeling and laminating pressure rollers are used to press against the edges of the target patch so that the target patch and the secondary adhesive tape are joined.
  • the peeling and laminating pressure rollers The roller surface is wrapped with a deformable protective structure.
  • the laminating mechanism includes a second blowing mechanism and a laminating support platform, and the second blowing mechanism and the laminating support platform are respectively provided on both sides of the third base material belt.
  • the second blowing mechanism can be close to or away from the fitting support platform; the second blowing mechanism is used to blow air to the target patch when approaching the fitting support platform, so that The target patch is joined to the secondary adhesive tape.
  • the number of the target patches is multiple
  • the second air blowing mechanism includes an air blowing platform
  • the air blowing platform is provided with a plurality of air outlets
  • the number and position of the air outlets are Corresponding to the number and position of the target patches
  • each target patch is blown by a corresponding air outlet
  • the aperture of the air outlet is larger than the diameter of the target patch.
  • the fourth processing line further includes a second visual inspection system that is communicatively connected to a control system, and the control system is used to control the laminating mechanism according to the visual inspection information of the second visual inspection system. status.
  • the present invention also provides a chip product processing method, which is implemented by any one of the chip product processing systems.
  • the patch product processing system includes: a first processing line, a second processing line, a third processing line and a fourth processing line; the third processing line One processing line, the second processing line and the third processing line run in parallel; the fourth processing line is serial with respect to the first processing line, the second processing line and the third processing line. Operation; the first processing line is used to process the original piece of the target object into a target object patch with a predetermined structure; the second processing line is used to process the primary anti-stick paper to form a secondary anti-sticking paper with hollows.
  • the present invention can realize continuous and large-volume automated production of patch-type target products, improve the processing efficiency and processing stability of the target products, and reduce processing costs.
  • the invention can realize parallel die-cutting of target original pieces, release paper, and adhesive tape, and improve the processing efficiency of patch-type target products.
  • the die-cut secondary adhesive tape, secondary release paper and target patch are automatically assembled and laminated, and peeled off into the corresponding packaging box. Subsequent sealing and packaging are automatically completed without manual intervention, while improving processing efficiency. At the same time, it improves the stability of product processing and ensures the quality of patch-type target products.
  • Figure 1 is a processing flow chart of a microneedle patch product provided by a preferred embodiment of the present invention
  • Figure 2 is a view of the patch product processing system provided by a preferred embodiment of the present invention, in which the arrows indicate the direction of the material. Conveying direction;
  • Figure 3a is an assembly view of the microneedle patch product provided by a preferred embodiment of the present invention.
  • Figure 3b is an exploded view of the microneedle patch product provided by a preferred embodiment of the present invention.
  • Figure 3c is a cross-sectional view of a microneedle patch product provided by a preferred embodiment of the present invention.
  • Figure 4 is a view of packaging a microneedle patch product according to a preferred embodiment of the present invention.
  • Figure 5 is a view of using waste discharge tape to recover microneedle original sheet cutting waste according to a preferred embodiment of the present invention
  • Figure 6 is a view of cutting an intermediate product to form multiple target products according to a preferred embodiment of the present invention.
  • Figure 7 is a view of the entire row of target products provided by a preferred embodiment of the present invention.
  • Figure 8 shows that when the original microneedle sheet provided by a preferred embodiment of the present invention is placed on the loading platform, a part of the original microneedle sheet extends out of the discharge side of the loading platform to rest on the first supporting material belt. view;
  • Figure 9 is a perspective view of a loading platform with adsorption holes provided by a preferred embodiment of the present invention.
  • Figure 10 is a cross-sectional view of the loading platform in Figure 9;
  • Figure 11 is a view of a loading platform with adsorption holes and a limiting baffle provided on the loading platform according to a preferred embodiment of the present invention
  • Figure 12 is a view showing the distribution of adsorption holes from sparse to dense along the discharge side direction provided by a preferred embodiment of the present invention.
  • Figure 13 is a view showing the distribution of adsorption pore diameters from small to large along the discharge side direction according to a preferred embodiment of the present invention
  • Figure 14 is a view of each row of adsorption structures provided with a separate negative pressure chamber along the discharge side direction according to a preferred embodiment of the present invention
  • Figure 15 is a view of a profiled conveyor belt forming a loading platform provided by a preferred embodiment of the present invention.
  • Figure 16 is a view of a first auxiliary pressing mechanism and a first blowing mechanism provided on the discharge side of the loading platform according to a preferred embodiment of the present invention
  • Figure 17 is a view of the feeding roller forming the feeding platform provided by a preferred embodiment of the present invention.
  • Figure 18 is a view of a partially movable limiting baffle provided by a preferred embodiment of the present invention.
  • Figure 19 is a view of the integral movable limiting baffle provided by a preferred embodiment of the present invention.
  • Figures 20 to 22 are views respectively showing that the shape of the pressure plate provided by a preferred embodiment of the present invention matches the shape of the exposed area on the original microneedle sheet;
  • Figures 23 and 24 are respectively distribution views of the air outlets provided by the first blowing mechanism provided by a preferred embodiment of the present invention.
  • Figure 25 shows a preferred embodiment of the present invention that uses a second auxiliary pressing mechanism to press the original microneedle sheet on the discharge side, and uses a first cleaning mechanism to remove dust from the original microneedle sheet on the discharge side. view;
  • Figure 26 is a view of cutting the original microneedle sheet to form multiple microneedle patches on the first backing tape according to a preferred embodiment of the present invention
  • Figure 27 is a view of a first-level adhesive tape supported by a third backing tape according to a preferred embodiment of the present invention, in which the number and position of the second-level adhesive tape corresponds to that of the microneedle patch;
  • Figure 28 is a view of multiple target products supported by a third support tape according to a preferred embodiment of the present invention, in which the microneedle patch and the secondary adhesive patch are bonded one by one;
  • Figure 29 is a view of the fitting mechanism provided by a preferred embodiment of the present invention.
  • Figure 30 is a view of the air blowing platform on the second air blowing mechanism provided by a preferred embodiment of the present invention.
  • Figure 31 is a view of using a peeling and laminating pressure roller to laminate a microneedle patch and a secondary adhesive patch, and using a second cleaning mechanism to remove dust from the microneedle patch, according to a preferred embodiment of the present invention.
  • front is relative to “rear”; “front” refers to the position where the material arrives first, “rear” relative to “front” is the position where the material is received later, and “front and back” refers to the position along the material's
  • the horizontal direction of the conveying direction “left and right” refers to the horizontal direction perpendicular to the conveying direction of the material; “forward” refers to the direction in which the material is conveyed from the front to the rear. As shown in Figure 2, the direction perpendicular to the paper surface is the left-right direction, and the direction parallel to the paper surface is the front-to-back direction. It should be understood that the materials in this article may refer to unprocessed products or processed products.
  • upstream is relative to “downstream”; “upstream” relative to “downstream” is usually the location where materials are processed or received first; “downstream” relative to “upstream” is usually the post-processing or post-receiving location The location of the material.
  • backing tapes used in this application are low-viscosity backing films, such as PET silicone films.
  • the invention discloses a patch product processing method, which includes:
  • the first processing line processes the original piece of the target object to form a target patch with a predetermined structure
  • the first-level release paper is processed by the second processing line to form a second-level release paper with hollows;
  • the first-level adhesive tape is processed by the third processing line to form a second-level adhesive tape with a predetermined structure
  • the second processing line joins the secondary adhesive tape with the secondary release paper to obtain a primary adhesive tape
  • the target patch is joined to the first-level adhesive tape by the fourth processing line, the target patch is placed in the hollow, and one side of the target patch is connected to the two Grade adhesive tape bonding.
  • Figure 1 shows a processing method for microneedle patch products disclosed in a preferred embodiment of the present invention, which includes first to fourth processing flows.
  • the first processing flow is implemented by the first processing line S1 to process the original microneedle sheet to form a microneedle patch with a predetermined structure, which specifically includes:
  • Step S11 loading the original piece of microneedle (that is, the original piece of the target object);
  • Step S12 cut the microneedle original piece to form a microneedle patch (i.e., target patch) with a predetermined structure (including a predetermined shape and size); the number of microneedle patches is generally multiple;
  • Step S13 Peel off the microneedle patch; specifically, peel off the microneedle patch and the first backing tape.
  • the second processing line S2 implements a second processing flow to process the primary release paper to form a secondary release paper with hollows, and also combine the secondary adhesive tape with the secondary release paper. After joining, the first-level adhesive tape is obtained, which includes:
  • Step S21 first-level release paper material
  • Step S22 cut the primary release paper to form a secondary release paper with hollows; the number and position of the hollows on the secondary release paper correspond to the number and location of the microneedle patches;
  • Step S23 peel off the secondary release paper; here, the primary release paper is cut to form hollowed waste, therefore, both the hollowed waste and the first backing tape need to be peeled off from the secondary release paper. It is convenient to join the peeled secondary release paper with the secondary adhesive tape in step S24;
  • step S24 the secondary release paper is joined to the secondary adhesive tape;
  • the adhesive tape can be made of hydrogel, hydrocolloid, non-woven tape and other adhesive materials.
  • steps S23 and S24 can be performed at the same time, or step S23 is performed first and step S24 is performed later.
  • the release paper can be used as release paper or other release paper with similar properties.
  • the third processing line S3 implements the third processing process to process the first-level adhesive tape to form a second-level adhesive tape with a predetermined structure, which specifically includes:
  • Step S31 loading the first-level adhesive tape
  • Step S32 cut the primary adhesive tape to form a secondary adhesive tape with a predetermined structure (predetermined shape and size); the number and location of the secondary adhesive tape correspond to the number and location of the microneedle patch;
  • step S24 is executed.
  • a primary adhesive tape is obtained.
  • the second-level release paper is joined to the adhesive surface of the second-level adhesive tape, and the second-level adhesive tape is exposed in the hollow to connect the microneedle patch.
  • a large piece of secondary release paper has multiple hollows, and each hollow is covered with a secondary adhesive tape. The area of the secondary adhesive tape is larger than the area of the hollow.
  • the fourth processing line S4 implements the fourth processing flow, which specifically includes step S41 of bonding the microneedle patch and the primary adhesive tape to obtain a target product including the microneedle patch.
  • the row of target products consists of a whole sheet of secondary release paper, multiple It consists of secondary adhesive tape and multiple target patches.
  • each target product is composed of a second-level adhesive sticker, a third-level release paper and a target patch.
  • the third-level release paper is cut and formed by the second-level release paper.
  • the third-level release paper There is a hollow in the middle, the target patch is inserted into the hollow, and one side of the target patch is bonded to the secondary adhesive tape.
  • microneedle side One side of the microneedle patch (microneedle side) is provided with multiple microneedles, and the other side of the microneedle patch (non-microneedle side) is adhered to the secondary adhesive tape.
  • the multiple microneedle patches The sheet is bonded to multiple secondary adhesive tapes in one-to-one correspondence.
  • the microneedle patch includes a base and a plurality of microneedles formed on the base. All microneedles are arranged in the central area of the base, and an edge area (ie, needle-free area) is formed on the periphery of the central area.
  • the base and microneedles can be made as a whole or in one piece, or they can be made separately.
  • the fourth processing flow also includes:
  • Step S42 After bonding the microneedle patch and the primary adhesive tape, an intermediate product is obtained, and then the intermediate product is cut to form multiple target products. Specifically, the secondary release paper on the intermediate product is cut to obtain multiple target products.
  • the fourth processing flow also includes:
  • Step S43 Peel off the target product, and the peeled target product can be automatically put into a packaging box.
  • the target product and the third support tape supporting the target product are peeled off, and the target product automatically falls into the packaging box after being peeled off from the third support tape.
  • the fourth processing flow also includes:
  • Step S44 After the packaging box is loaded, the packaging box is automatically sealed by a sealing machine.
  • the packaging box is a blister box
  • the blister box is plastic-sealed.
  • each target product 600 is composed of a second-level adhesive tape 601, a third-level release paper 602 and a microneedle patch 603. .
  • the third-level release paper 602 is formed by cutting the second-level release paper, and the middle part of the third-level release paper 602 has a hollow, and the shape of the hollow generally corresponds to the shape of the microneedle patch 603; so The microneedle patch 603 is placed in the hollow space, and one side of the microneedle patch 603 is bonded to the secondary adhesive tape 601 . All target products 600 have the same shape and size.
  • the size of the third-level release paper 602 can be the same as the size of the second-level adhesive tape 601, so that after lamination, the edges of the third-level release paper 602 and the second-level adhesive tape 601 almost overlap.
  • the edge of the third-level release paper 602 extends beyond the edge of the second-level adhesive tape 601 to form an exposed third-level release paper 602 on the periphery of the second-level adhesive tape 601.
  • the edge of the hollow is set. Considering that the size of the third-level release paper 602 is too small, it is inconvenient for the user to operate. Therefore, the size of the third-level release paper 602 is larger than the size of the second-level adhesive tape 601. The user can directly tear off the second-level adhesive tape 601.
  • the third-level release paper 602 can be quickly and easily torn off, making the operation more convenient.
  • release paper and hydrocolloid as an example.
  • the release paper is used to protect the hydrocolloid surface exposed to the microneedle patch 603 from contamination or reduction in adhesive force caused by contact with air or foreign objects.
  • a row of target products 600' can be processed, which is composed of a secondary release paper 602', a plurality of secondary adhesive patches 601 and a plurality of microneedle patches 603.
  • the secondary adhesive patch 601 is bonded to the microneedle patch 603 in one-to-one correspondence.
  • Figure 4 is a specific example of packaging the target product 600 according to the present invention.
  • the fourth processing line S4 can automatically load the peeled target product 600 into the packaging box 700 , and finally seal the packaging box 700 .
  • the packaging box 700 may include a box body and a box lid 800.
  • the target product 600 is placed in the box body. After the box lid 800 and the box body are closed, they are plastic-sealed by a sealing machine. It should be understood that since the non-adhesive surface of the target product 600 is exposed, the target product 600 can be directly placed in the packaging box 700 after being peeled off from the third support tape, thus avoiding manual sampling with a sampler, such as using non-woven fabrics.
  • the adhesive tape sticks to the target product, and then the non-woven tape is attached to the designated sampling area of the packaging box, which effectively saves processing time and increases processing efficiency.
  • the shape of the inner cavity of the packaging box 700 matches the shape of the target product 600 to better fix the target product 600, effectively prevent the target product 600 from shaking, and reduce the risk of damage.
  • an embodiment of the present invention also provides a chip product processing system that implements the above chip product processing method.
  • the chip product processing system includes a first processing line S1, a second processing line S2, and a second processing line S2.
  • the third processing line S3 and the fourth processing line S4; the first processing line S1, the second processing line S2 and the third processing line S3 run in parallel; the fourth processing line S4 is relative to the first processing line S3.
  • the processing line S1, the second processing line S2 and the third processing line S3 run in series; the first processing line S1 is used to process the microneedle original piece 500 into a predetermined structure (shape and size).
  • Microneedle patch 603; the second processing line S2 is used to process the first-level release paper into a hollow second-level release paper 602'; the third processing line S3 is used to process the first-level adhesive tape, Processing to form a secondary adhesive tape 601 with a predetermined structure (shape and size); the second processing line S2 is also used to join the secondary adhesive tape 601 with the secondary release paper 602', A first-level adhesive tape is obtained; the fourth processing line S4 is used to join the microneedle patch 603 with the first-level adhesive tape to obtain the target product 600 or 600'.
  • the patch product processing system can realize parallel die-cutting of microneedle original sheets, release paper, and adhesive tape, thereby improving the processing efficiency of microneedle patches.
  • the die-cut secondary adhesive tape, secondary release paper and microneedle patch are automatically assembled and laminated, and peeled off into the corresponding packaging box. Subsequent sealing and packaging are automatically completed without manual intervention, while improving processing efficiency. At the same time, it improves the stability of product production and ensures the quality of microneedle patch products.
  • the fourth processing line S4 is configured to first join the microneedle patch 603 with the first-level adhesive tape to obtain an intermediate product, and then cut the intermediate product to form multiple target products. 600.
  • the intermediate product can be eliminated and the secondary release paper does not need to be cut again.
  • the fourth processing line S4 can directly process the rows of target products 600'.
  • the first processing line S1 includes a first supporting material belt 1011, a first die-cutting mechanism 104, a first peeling mechanism 106, a first waste collection mechanism 105 and a second waste collection Mechanism 107
  • the first supporting material belt 1011 can move from the upstream to the downstream direction of the first processing line S1; the first processing line S1 can move from the upstream to the downstream direction.
  • the first supporting material belt 1011 can drag the original microneedle sheet 500 to be transported downstream; the first die-cutting mechanism 104 is located at the die-cutting station A2. There is a first cutting knife 1041 and a first die-cutting support roller 1042.
  • the first die-cutting support roller 1042 and the first cutting knife 1041 are respectively located on two opposite sides of the first supporting material belt 1011, as shown in the first A die-cutting support roller 1042 is located below the first supporting material belt 1011, and a first cutter 1041 is above the first supporting material belt 1011.
  • the first cutting knife 1041 is used to cut the microneedle original sheet 500 to form Microneedle patch 603; the first waste collection mechanism 105 collects the waste material formed after the microneedle original piece 500 is cut at the first waste collection station A3; the first peeling mechanism 106 operates at the peeling station A4 is provided with a first peeling knife, which is disposed on the side of the first backing strip 1011 away from the microneedle patch 603; the first peeling knife is supported by its two adjacent sides.
  • the first supporting material strip 1011 changes the first supporting material strip 1011 from the initial horizontal extension direction to the diagonally downward extension direction at the first peeling knife, thereby peeling off the microneedle patch 603
  • the first supporting material belt 1011 that is, the first supporting material belt 1011 is formed into two parts with different extending directions through the first peeling knife, and the angle ⁇ between the two parts of the first supporting material belt 1011 is less than 90 °, preferably ⁇ is less than or equal to 30°;
  • the second waste collection mechanism 107 recycles the first bottoming material strip 1011 at the second waste collection station A5.
  • the first processing line S1 can realize automatic die cutting and peeling of the microneedle original piece 500, and also realize automatic recycling of waste materials.
  • the loading of the microneedle original piece can also be automated, and the entire process does not require manual intervention. , high processing efficiency and good processing stability.
  • the first waste collection mechanism 105 is provided with a first waste collection pressure roller 1051 and a first waste collection support roller 1052 at the first waste collection station A3.
  • the first waste collection support roller 1052 and the first waste collection pressure roller 1051 are respectively located on two opposite sides of the first bottom support belt 1011.
  • the first waste collection support roller 1052 is located below the first bottom support belt 1011.
  • the pressure roller 1051 is located above the first supporting material belt 1011; the first waste collecting mechanism 105 is also provided with a waste discharge tape 1055, a feeding reel 1053 and a discharging reel 1054; the feeding reel 1053, the The first waste collection pressure roller 1051 and the discharge drum 1054 are connected through the waste discharge tape 1055 in turn; the waste discharge tape 1055 is sent out from the feeding drum 1053 and passes through the first waste collection pressure roller 1051 is pressed against the waste material formed by cutting the original microneedle sheet 500 and bonded to it, and the waste discharge tape 1055 bonding the waste material is recovered by the discharge reel 1054 .
  • the second waste collection mechanism 107 is provided with a first waste collection drum winding the first bottoming material strip 1011 at the second waste collection station A5.
  • a first waste collection drum winding the first bottoming material strip 1011 at the second waste collection station A5.
  • the first waste collection pressure roller 1051 is used to press the waste discharge tape 1055 against the edge of the microneedle original sheet 500 to avoid damaging the microneedle structure in the middle part of the microneedle original sheet 500 .
  • the first waste collection pressure roller 1051 is preferably dumbbell-shaped and can simultaneously press two waste discharge tapes 1055 on the edges of the microneedle original sheet 500. Without touching the microneedle area of the cut microneedle original piece 500.
  • the distance between the left and right pressure wheels of the first waste collection pressure roller 1051 is adjustable or fixed. If the distance is adjustable, it can adapt to different sizes of microneedle original sheets.
  • the first processing line S1 further includes a first pressing mechanism 102 capable of tensioning the first base material belt 1011 ; the first processing line S1 also includes a Pressing station A6 is located upstream of the loading station A1; the first pressing mechanism 102 is provided with a first pressing support roller 1022 at the pressing station A6. and the first pressing roller 1021, the first pressing support roller 1022 and the first pressing roller 1021 are respectively located on two opposite sides of the first supporting material belt 1011, such as the first pressing support The roller 1022 is below the first supporting material belt 1011 , and the first pressing roller 1021 is above the first supporting material belt 1011 .
  • the arrangement of the first pressing mechanism 102 can further straighten and tighten the first supporting material belt 1011 to ensure processing accuracy.
  • the number of the first pressing mechanisms 102 may be one or more arranged side by side.
  • the first processing line S1 also includes a first support strip material roll 101 located at the most upstream, and the first support strip material roll 101 is provided with a rolled first support. Material tape 1011.
  • the first supporting material tape roll 101 can also pull, transport, and tension the first supporting material tape 1011.
  • the first backing strip material roll 101 the first pressing mechanism 102, the first die-cutting mechanism 104, the first waste collection mechanism 105 and the second waste collection mechanism 107 can be used.
  • the function of pulling and transporting the first supporting material belt 1011 is achieved, and the first peeling mechanism 106 can also realize the turning and conveying of the first supporting material belt 1011 .
  • the first processing line S1 also includes a loading platform 103 for placing the original microneedle sheet 500, and the loading platform 103 is provided at the loading station A1.
  • the microneedle original piece 500 when the microneedle original piece 500 is placed on the loading platform 103, the microneedle original piece 500 A part of the sheet 500 is used to extend out of the discharge side S of the loading platform 103 to rest on the first supporting material belt 1011.
  • the discharge side S is close to the die-cutting station A2.
  • the loading platform 103 can absorb the microneedle original sheet 500 to prevent the microneedle original sheet 500 from rising when it is attached to the first backing tape 1011 .
  • the loading platform 103 itself can move and/or rotate. Through the movement and/or rotation of the loading platform 103, a part of the original microneedle piece 500 is pushed out of the discharge side S of the loading platform 103.
  • the loading platform 103 adsorbs (including vacuum adsorption or non-vacuum adsorption) the microneedle original piece 500 under negative pressure. In another embodiment, the loading platform 103 electrostatically adsorbs the original microneedle piece 500 .
  • the loading platform 103 is provided with a plurality of adsorption holes 1031 , and a negative hole connected to the adsorption holes 1031 is formed inside the loading platform 103 .
  • Pressure chamber 1034 After the microneedle original piece 500 is placed on the loading platform 103, the loading platform 103 turns on negative pressure adsorption to fix the microneedle original piece 500 on the loading platform 103.
  • the function of the adsorption hole 1031 is to, on the one hand, fix the microneedle original piece 500 on the loading platform 103 to prevent the mechanical vibration from causing the microneedle original piece 500 to shift, and on the other hand, the first supporting material belt 1011 drags the microneedle original piece 500 .
  • the sheet is 500
  • the original sheet of microneedle 500 is kept flat for a long time.
  • the adsorption holes 1031 may be uniformly distributed or unevenly distributed, and the distribution form is not limited to the rectangular array shown in the figure.
  • a plurality of the adsorption holes 1031 are distributed from sparse to dense along the discharging direction A of the microneedle original sheet 500 .
  • the plurality of adsorption holes 1031 are distributed from dense to sparse along the discharging direction A of the microneedle original sheet 500 .
  • a plurality of the adsorption holes 1031 are distributed from sparse to dense along the discharging direction A of the microneedle original sheet 500, which can better ensure the microneedle removal when the first supporting material belt 1011 drags the microneedle original sheet 500.
  • the original film is 500 flat.
  • the plurality of adsorption holes 1031 are distributed from dense to sparse or from sparse to dense along the direction perpendicular to the discharging direction A.
  • the distribution density of the plurality of adsorption holes 1031 is sparse in the middle and dense at the edges, or dense in the middle and sparse at the edges; that is, the distribution density of the adsorption holes 1031 in the middle part of the loading platform 103 is small, and the adsorption at the edge parts is small.
  • the distribution density of the pores 1031 is large, or the distribution density of the adsorption pores 1031 in the middle part is large, and the distribution density of the adsorption pores 1031 in the edge part is small.
  • the pore size distribution of the adsorption pores 1031 can also be adjusted. As shown in FIG. 13 , in one embodiment, the pore diameters of the plurality of adsorption holes 1031 are distributed from small to large along the discharging direction A. In other embodiments, the pore diameters of the plurality of adsorption holes 1031 are distributed from large to small along the discharging direction A. Preferably, a plurality of the adsorption holes 1031 are distributed from small to large along the discharging direction A of the microneedle original sheet 500, which can better ensure the microneedle dispersion when the first supporting material belt 1011 drags the microneedle original sheet 500.
  • the pore diameters of the plurality of adsorption holes 1031 are such that the pore diameters of the adsorption holes 1031 in the middle part of the loading platform 103 are large, and the pore diameters of the adsorption holes 1031 in the edge part of the loading platform 103 are small, or in the middle part.
  • the adsorption holes 1031 in the edge part have a small diameter, and the adsorption holes 1031 in the edge part have a large diameter.
  • the pore diameters of the plurality of adsorption holes 1031 are distributed from large to small or from small to large along the direction perpendicular to the discharging direction A.
  • the microneedle original piece 500 being gradually separated from the loading platform 103 by the first supporting material belt 1011, in order to ensure the smoothness of the microneedle original piece 500, it is preferable to form a plurality of the microneedle original pieces 500 arranged independently inside the feeding platform 103. Negative pressure chamber 1034, at least some of the adsorption holes 1031 do not share the same negative pressure chamber 1034. Such an arrangement not only facilitates the discharging of the microneedle original sheet 500, but also effectively ensures the smoothness of the microneedle original sheet 500 during the discharging process.
  • multiple negative pressure cavities 1034 are arranged along the discharging direction A, so that multiple adsorption areas are arranged in the discharging direction A, and these adsorption areas are independent of each other.
  • multiple negative pressure cavities 1034 are arranged perpendicular to the discharging direction A to form multiple independent adsorption areas perpendicular to the discharging direction A.
  • some of the plurality of negative pressure cavities 1034 are distributed in the middle part of the loading platform 103, and others are distributed in the edge part of the loading platform 103, so that between the middle part and the edge of the loading platform 103 Partially form mutually independent adsorption regions. It should be understood that in the present invention, the middle part of the loading platform 103 cannot be understood in a narrow sense as an absolute middle position, but should be understood as an area surrounded by edge parts.
  • the loading platform 103 forms multiple rows of adsorption structures along the discharging direction A.
  • Each row of the adsorption structures includes an adsorption structure along a direction perpendicular to the discharging direction.
  • a plurality of adsorption holes 1031 are arranged sequentially in the material direction A, and multiple rows of the adsorption structures form a multi-row and multi-column matrix, such as an n-row and m-column matrix; the adsorption holes 1031 in some adjacent rows do not share the same negative
  • the pressure chamber 1034 and/or the adsorption holes 1031 in some adjacent columns do not share the same negative pressure chamber 1034.
  • n1 is smaller than n
  • m1 is smaller than m.
  • a separate negative pressure chamber 1034 is provided for each row of adsorption structures, and all adsorption structures are mutually They do not share the same negative pressure chamber 1034.
  • the adsorption holes 1031 can be opened or closed sequentially along the discharging direction A.
  • the function of the negative pressure cavity 1034 is to provide negative pressure suction for the adsorption hole 1031.
  • the microneedle original piece 500 is placed on the loading platform 103, and the original microneedle piece 500 can be adsorbed by negative pressure to prevent the deviation of the original microneedle piece caused by the vibration of the mechanism.
  • the negative pressure adsorption can drag the original microneedle piece 500 on the first supporting material belt 1011. During the tableting process, the smoothness of the original microneedle tablet is maintained for a long time.
  • the adsorption holes 1031 far away from the discharge side S will be gradually exposed to the outside of the original microneedle piece; at this time, if all the adsorption holes share the same negative pressure chamber, or all the negative pressure chambers are connected to each other, once some adsorption holes are If exposed, the negative pressure environment of the entire negative pressure chamber will be broken, and the suction force will drop significantly, which will greatly affect the suction force of the working adsorption holes under the original microneedle piece; when each negative pressure chamber is independently set up along the discharging direction A, the exposed The adsorption hole will not affect the suction of other adsorption holes set independently of it, so that the working adsorption hole under the original microneedle piece maintains good suction, so that the bottom material belt drags the original piece of microneedle, and the microneedle original piece is maintained for a long time. Needle the flatness of the original piece.
  • the structure of the feeding platform 103 is not limited.
  • it can be a vacuum feeding platform with a simple adsorption function.
  • the loading platform 103 can also be a contoured conveyor belt 103a with adsorption function, as shown in Figure 15.
  • the contoured conveyor belt 103a may not have an adsorption function, but may simply load and transport the original microneedle sheets 500.
  • the profiling conveyor belt 103a is sequentially provided with a plurality of partitions 1032 along the conveying direction, and there is a conveying section between adjacent partitions 1032.
  • the transfer section is used to place a microneedle original piece 500; in this way, the microneedle original piece 500 can be loaded continuously and quickly.
  • the first processing line S1 may also include an auxiliary bonding mechanism for joining the original microneedle piece 500 with the first backing material tape 1011 (joining includes bonding or adhesion), so The first processing line S1 is also provided with an auxiliary laminating station A7.
  • the auxiliary laminating station A7 is located between the loading station A1 and the die-cutting station A2; the first supporting base
  • the material belt 1011 is transported from below the profiling conveyor belt 103a, and passes from bottom to top between the discharge side S of the profiling conveyor belt 103a and the auxiliary fitting mechanism; wherein each of the partitions 1032 protrudes
  • the height of the conveying surface of the contoured conveyor belt 103a is smaller than the gap width b between the discharge side S and the auxiliary laminating mechanism.
  • a gap is formed between the discharge side S and the auxiliary fitting mechanism. In the gap area, the contoured conveyor belt 103a bends and moves downward.
  • the partition 1032 will change from the vertical direction to the horizontal direction for an instant. In order to prevent the partition 1032 from getting stuck, the height of the partition 1032 protruding from the transmission surface needs to be less than the gap width b.
  • the loading platform 103 can also electrostatically adsorb the microneedle original piece 500, for example, the loading platform 103 is configured as an electrostatic chuck.
  • the advantage of the electrostatic chuck is that there is no air leakage problem during the movement of the original microneedle piece, and the stability of the electrostatic adsorption force is good.
  • the loading platform 103 can also be configured to consist of multiple loading rollers 1033 arranged side by side, as shown in Figure 17 .
  • the microneedle original sheet 500 is placed on the feeding roller 1033, and the feeding movement of the microneedle original sheet 500 can be realized by utilizing the rotation of the feeding roller 1033.
  • the feeding roller 1033 may only rotate without having an adsorption function, or the feeding roller 1033 may have a negative pressure adsorption function or an electrostatic adsorption function.
  • the loading platform 103 itself may or may not move.
  • the loading platform 103 itself is movable, such as through the contoured conveyor belt 103a or through the loading roller 1033, or the loading platform 103 is driven by an external driving device to be movable. Through the movement of the loading platform 103 itself, a part of the original microneedle piece 500 can be pushed out of the discharge side S of the loading platform 103 .
  • a limiting baffle 108 is used to prevent the microneedle original sheet 500 from moving outside the discharging direction A. direction to move in the direction of the original microneedle piece 500.
  • the size of the limiting baffle 108 is adjustable or non-adjustable.
  • the size of the limiting baffle 208 is adjustable to accommodate loading of microneedle original sheets 500 of different shapes and sizes.
  • the limiting baffle 108 includes two side baffles 1081 and a push plate 1082; the two side baffles 1081 are arranged on two opposite sides of the push plate 1082; the push plate 1082 is movably connected to the two side baffles 1081; the push plate 1082 can not only push the original microneedle piece 500 in the direction of arrow B, but also change the size of the limiting baffle 108.
  • part of the structure of the limiting baffle 108 (such as the push plate 1082) can move relative to the loading platform 103 to push a part of the original microneedle piece 500 out of all parts of the loading platform 103. Describe the discharge side.
  • the entire structure of the limiting baffle 108 can move relative to the loading platform 103 .
  • the limiting baffle 108 is an integrated curved push plate 108a.
  • the curved push plate 108a is a whole or one-piece structure, which surrounds and is used to push the microneedle original piece 500.
  • the limit baffle 108 is pushed forward as a whole.
  • the limiting baffle 108 can be driven to move by a driving device.
  • the driving device includes but is not limited to a motor.
  • At least one of the loading platform 103 and the limiting baffle 108 can move.
  • the microneedle original piece 500 is pushed to the auxiliary laminating station A7 by the loading platform 103, which can avoid loading because the microneedle original piece 500 is too thin and the gap between the pushing plate and the loading platform 103 is large. Difficult question, at this time, the limiting baffle 108 can be used only in position.
  • the auxiliary laminating mechanism includes a first auxiliary pressing mechanism 109.
  • the first auxiliary pressing mechanism 109 includes pressure plates 1091 provided on two opposite sides of the first base material belt 1011.
  • the pressing plate 1091 is provided above the first supporting material belt 1011, and the laminating plate 1092 is provided below the first supporting material belt 1011; the pressing plate 1091 can be close to or away from the laminating plate 1092, the The pressing plate 1091 can press the edge of the microneedle original sheet 500 when it is close to the laminating plate 1092, so that the edge of the microneedle original sheet 500 is attached to the rubber surface of the edge of the first backing strip 1011.
  • the arrangement of the first auxiliary pressing mechanism 109 can achieve a close fit between the edge of the original microneedle piece and the first backing material strip 1011 .
  • the pressure plate 1091 is connected to the cylinder through a connecting rod.
  • the control system controls the opening cylinder, and acts on the pressure plate 1091 through the connecting rod, and the pressure plate 1091 moves downward to press the edge of the original microneedle piece 500 with the first base material belt 1011.
  • the control system controls the cylinder to drive the pressure plate 1091 to lift upward and restore the initial state.
  • the first supporting material belt 1011 continues to move, dragging the original microneedle piece 500 to the next work station.
  • a linear motor for example, a linear motor, an electromagnetic hydraulic mechanism, a pendulum mechanism, etc. may be used to drive the movement of the pressure plate 1091.
  • the first auxiliary pressing mechanism 109 is not limited to being provided as one, but may also be provided as a plurality of them arranged side by side in sequence.
  • the pressing plate 1091 contacts the edge of the microneedle original piece 500, and makes the edge of the microneedle original piece 500 fit the first supporting material belt 1011. During this process, the pressing plate 1091 preferably does not contact the first supporting material belt 1011. So as not to be affected by the adhesive force of the first backing tape 1011.
  • the shape of the pressing plate 1091 preferably matches the shape of the microneedle original piece 500 when it is exposed (extended) from the loading platform 103 . As shown in FIGS. 20 to 22 , the section line filling area is a pressing plate 1091 , and the shape of the pressing plate 1091 matches the shape of the exposed area 103 b formed by the microneedle original piece 500 extending out of the loading platform 103 .
  • the laminating plate 1092 is on the discharging side S of the loading platform 103, supports the first base material belt 1011 at the auxiliary laminating station A7, and forms a gap with the discharging side S of the loading platform 103.
  • the first The bottom material belt 1011 passes between the loading platform 103 and the laminating plate 1092 from bottom to top to be further transported above the laminating plate 1092; in one embodiment, the gap width between the laminating plate 1092 and the discharging side b is greater than the height of the partition 1032.
  • the auxiliary laminating mechanism includes a first blowing mechanism 110 for blowing air to the microneedle original sheet 500 so that the microneedle original sheet 500 is in contact with the first supporting base.
  • the material tape is 1011 fit.
  • the first blowing mechanism 110 and the first auxiliary pressing mechanism 109 can be provided alternatively or simultaneously.
  • the first air blowing mechanism 110 adopts non-contact air blowing, which can better protect the microneedle structure and prevent product contamination.
  • the gas blown out by the first blowing mechanism 110 needs to be processed by the air outlet 1101 to form a uniform air flow beam.
  • the first air blowing mechanism 110 has a plurality of air outlets 1101 .
  • the air outlets 1101 are distributed in a matrix form, and the shapes of the air outlets 1101 can be various.
  • the first blowing mechanism 110 blows directly against the original microneedle sheet 500 .
  • the auxiliary laminating mechanism includes both a first auxiliary pressing mechanism 109 and a first blowing mechanism 110.
  • the first blowing mechanism 110 is provided upstream or downstream of the first auxiliary pressing mechanism 109. downstream.
  • the number of the first blowing mechanism 110 may be one or multiple first blowing mechanisms 110 arranged side by side.
  • the patch product processing system also includes a first visual inspection system 501 that is communicatively connected to a control system.
  • the control system is used for visual inspection according to the first visual inspection system 501.
  • the information controls the discharging and loading of the microneedle original piece 500.
  • the discharging of the original microneedle sheet 500 means that the original microneedle sheet 500 is separated from the loading platform 103 ; the loading of the original microneedle sheet 500 means that the original microneedle sheet 500 is placed on the loading platform 103 .
  • the control system when the first visual detection system 501 detects that the loading platform 103 is in the loading state of receiving the microneedle original piece 500, the control system first controls the loading platform 103 to turn on the adsorption function. , the microneedle original sheet 500 is fixed on the loading platform 103. At this time, part of the microneedle original sheet 500 extends out of the discharge side of the loading platform 103. Then, the control system controls the first auxiliary pressing mechanism 109 Open, the pressing plate 1091 moves downward, and the part of the microneedle original piece 500 that extends out of the loading platform 103 is attached to the first supporting material belt 1011. After that, the pressing plate 1091 moves upward to reset.
  • the first supporting material belt 1011 drags the original microneedle piece 500 away from the loading platform 103.
  • the control system controls the first air blowing mechanism 110 to blow air so that the original microneedle piece 500 is completely attached. Closed on the first supporting material belt 1011.
  • the first visual inspection system 501 detects that the loading platform 103 is in an unloading state that does not accept the microneedle original piece 500, that is, the microneedle original piece 500 is completely dragged away from the loading platform 103 by the first supporting material belt 1011.
  • a visual inspection system 501 notifies the control system to re-place the original microneedle piece 500 on the upper material platform 103 .
  • the limiting baffle 108 can realize the precise positioning and placement of the microneedle original piece 500.
  • the loading platform 103 to adsorb and fix the microneedle original piece 500, combined with the control of the first visual inspection system 501, accurate and continuous loading of the microneedle original piece 500 can be achieved, and the processing accuracy is higher.
  • the auxiliary laminating station A7 includes an auxiliary laminating station and an auxiliary laminating station.
  • the auxiliary laminating station is arranged upstream of the auxiliary laminating station.
  • the first auxiliary laminating station A7 The pressing mechanism 109 joins the edge of the original microneedle piece 500 to the first supporting material belt 1011 before the auxiliary pressing station. Then, the first supporting material belt 1011 moves. The microneedle original piece 500 is dragged to the auxiliary laminating station.
  • the first blowing mechanism 110 is at the auxiliary laminating station to completely fit the entire microneedle original piece 500 on the first backing material belt 1011 .
  • the first visual inspection system 501 detects that after the microneedle original piece 500 reaches the auxiliary pressing station, the first supporting material belt 1011 remains motionless, and then the control system controls to open the first auxiliary pressing mechanism 109 to complete the microneedle original piece. The edge of the piece is initially attached to the first supporting material belt 1011, and then the first supporting material belt 1011 moves to drag the original microneedle piece 500 to the auxiliary laminating station.
  • the first visual inspection system 501 detects the microneedle After the needle original piece 500 reaches the auxiliary laminating station, the first backing material belt 1011 stops moving, and then the control system controls to open the first blowing mechanism 110 to complete the entire microneedle original piece 500 and the first backing material belt 1011 After completely fitting, the first backing material belt 1011 continues to move, dragging the original microneedle piece 500 to the next work station.
  • the patch product processing system may also include a control system that is communicatively connected to each processing line to control the automated operation of each processing line.
  • each processing line can have a separate control system, or all processing lines can share a control system.
  • the control system is mainly connected through communication with the electrical components in the processing line, thereby controlling the automated operation of the moving parts in these processing lines, realizing the automated production of microneedle patches, and improving processing efficiency.
  • This embodiment has no special restrictions on the type of control system. It can be hardware that performs logic operations, such as a single-chip computer, a microprocessor, a programmable logic controller (PLC, Programmable Logic Controller) or a field programmable logic gate array (FPGA).
  • PLC programmable logic controller
  • FPGA field programmable logic gate array
  • the type of the first visual inspection system 501 is not limited.
  • an AI vision system or other commonly used visual inspection equipment can be used.
  • the auxiliary laminating mechanism may include a second auxiliary laminating mechanism 111.
  • the second auxiliary laminating mechanism 111 may include first auxiliary laminating pressure rollers located on two opposite sides of the first base material belt 1011. 1111 and the first auxiliary laminating support roller 1112; the first auxiliary laminating pressure roller 1111 can be close to or away from the first auxiliary laminating support roller 1112; the first auxiliary laminating pressure roller 1111 can be close to the When the first auxiliary laminating support roller 1112 is pressed against the edge of the microneedle original sheet 500, the edge of the microneedle original sheet 500 is bonded to the first backing material strip 1011.
  • the roller surface of the first auxiliary laminating pressure roller 1111 is provided with a deformable protective structure, such as a protective structure made of dust-free foam or other soft materials, which can protect the microneedles and reduce the risk of damage to the microneedle structure. risk.
  • the roller surface of the first auxiliary laminating pressure roller 1111 is covered with a protective structure to achieve comprehensive protection.
  • the second auxiliary pressing mechanism 111 can be provided alone, or can be used in combination with auxiliary laminating mechanisms of other structures.
  • the second auxiliary pressing mechanism 111 may be one or a plurality of them arranged side by side. In this embodiment, the second auxiliary pressing mechanism 111 can also tension, pull and transport the first bottoming material belt 1011.
  • the first visual inspection system 501 detects that the microneedle original piece 500 is placed on the loading platform 103. , notify the control system, and the control system controls the driving device to drive the limit baffle 108 to push the original microneedle piece 500 to the first auxiliary laminating pressure roller 1111, so that the first auxiliary laminating pressure roller 1111 presses the edge of the original microneedle piece. It is attached to the first supporting material belt 1011.
  • the first visual inspection system 501 detects that the microneedle original piece 500 has been completely separated from the feeding platform 103 by the first supporting material belt 1011, it notifies the control system to load the feeding platform again. 103.
  • the original microneedle piece is 500.
  • the first processing line S1 further includes a first cleaning mechanism 112 for removing microneedles in a non-contact manner downstream of the loading station A1 and upstream of the die-cutting station A2.
  • Foreign matter such as dust or other impurities
  • the first cleaning mechanism 112 can remove foreign matter attached to the microneedle original sheet 500 due to static electricity or other reasons to ensure the cleanliness of the product.
  • the first cleaning mechanism 112 generates ionic wind for dust removal.
  • the number of first cleaning mechanisms 112 is not limited, such as one or more first cleaning mechanisms 112 .
  • the second processing line S2 includes a second supporting material belt 2011 , a second pressing mechanism 203 , a second die-cutting mechanism 204 , and a third pressing mechanism 205 and a third waste collection mechanism 206.
  • the second supporting material belt 2011 is used to move from the upstream to the downstream direction of the second processing line S2; the second processing line S2 is provided with first Pressing station B1, die-cutting station B2, second pressing station B3 and waste collection station B4; the second pressing mechanism 203 is provided with a second pressing station at the first pressing station B1
  • the support roller 2032 and the second pressing roller 2031; the second pressing support roller 2032 and the second pressing roller 2031 are respectively located on two opposite sides of the second supporting material belt 2011, such as the second The pressing roller 2031 is above the second supporting material belt 2011, and the second pressing support roller 2032 is below the second supporting material belt 2011, so as to press the second supporting material belt 2011 and the primary anti-protection device together.
  • the adhesive paper 2021 connects the second backing material strip 2011 with the primary release paper 2021; the second die-cutting mechanism 204 is provided at the die-cutting station B2 of the second processing line S2.
  • the second die-cutting support roller 2041 and the second cutter 2042 are respectively located on two opposite sides of the second base material belt 2011, such as the second die-cutting support roller 2041 and the second cutter 2042.
  • the die-cutting support roller 2041 is located above the second supporting material belt 2011, and the second cutter 2042 is located below the second supporting material belt 2011.
  • the second cutter 2042 is used to cut the primary release paper 2021 to form the secondary release paper 602'; the third pressing mechanism 205 is provided at the second pressing station B3.
  • the third pressing roller 2051 is provided on one side of the second backing tape 2011 (the side facing away from the release paper) to press the secondary release paper. Paper 602' and the secondary adhesive tape 601 (processed and formed by the third processing line S3), so that the secondary release paper 602' and the secondary adhesive tape 601 are joined;
  • the waste mechanism 206 collects the first-level release paper 2021 through the second support material belt 2011 at the waste collection station B4 after being cut to form waste material corresponding to the hollow, and makes the second support material belt 2011 is separated from the secondary release paper 602' at the second pressing station B3.
  • the third waste collection mechanism 206 is provided with a second waste collection drum winding the second bottoming material strip 2011 at the waste collection station B4.
  • the second processing line S2 also includes a second backing tape material roll 201 and a first-level release paper material roll 202 located at the most upstream.
  • the second backing tape material roll 201 A roll of second backing tape 2011 is provided, and the first-level release paper material roll 202 is provided with a roll of first-level release paper 2021.
  • the second backing strip material roll 201 and the first-level release paper material roll 202 are provided with a roll of first-level release paper 2021.
  • the rolls 202 of grade release paper materials are arranged independently of each other.
  • the second backing material tape 2011 and the first-level anti-adhesive paper 2021 are closely adhered by the second pressing mechanism 203, and then die-cut by the second die-cutting mechanism 204 to cut out the hollows.
  • the third pressing The mechanism 205 is used to realize the lamination of the secondary adhesive tape 601 and the secondary anti-adhesive paper 602'. Before the lamination, the third waste collection mechanism 206 needs to collect a third waste material strip 2011 while collecting it. Hollow waste formed by cutting grade release paper 2021. It should be understood that the second pressing mechanism 203 and the third pressing mechanism 205 can also keep the second supporting material belt 2011 in a tight state, and the arrangement of the second supporting material belt 2011 can reduce the friction of the release paper. force, reducing its deformation, and ultimately ensuring the positional accuracy of die-cutting and lamination of the release paper.
  • the second backing strip material roll 201, the second pressing mechanism 203, the second die-cutting mechanism 204, the third pressing mechanism 205, and the third waste collection mechanism 206 are also The second supporting material belt 2011 can be pulled and transported.
  • the third processing line S3 includes a third support belt 3021, a fourth pressing mechanism 303, a third die-cutting mechanism 304, a fourth waste collection mechanism 305 and a fifth pressing mechanism. 306.
  • the third supporting material belt 3021 is used to move from the upstream to the downstream direction of the third processing line S3; the third processing line S3 is provided with the first pressing station C1, Die-cutting station C2 and waste collection station C3, the third processing line S3 is also provided with a second pressing station C4, and the second pressing station C1 of the third processing line S3 is located at The third processing line S3 is downstream of the die-cutting station C2 and is arranged in parallel with the waste collection station C3 of the third processing line S3; the fourth pressing mechanism 303 is located in the third processing line S3.
  • the first pressing station C1 of the processing line S3 is provided with a fourth pressing support roller 3032 and a fourth pressing roller 3031.
  • the fourth pressing support roller 3032 and the fourth pressing roller 3031 They are respectively located on two opposite sides of the third supporting material belt 3021.
  • the fourth pressing support roller 3032 is provided below the third supporting material belt 3021
  • the fourth pressing pressure roller 3031 is provided on the third supporting material belt 3021.
  • the third backing material belt 3021 and the first-level adhesive tape 3011 are pressed together, so that the third backing material belt 3021 and the first-level adhesive tape are joined together; the third mold
  • the cutting mechanism 304 is provided with a third cutting knife 3041 and a third die-cutting support roller 3042 at the die-cutting station C2 of the third processing line S3.
  • the third die-cutting support roller 3042 and the third die-cutting support roller 3042 are The knives 3041 are respectively located on two opposite sides of the third supporting material belt 3021.
  • the third die-cutting support roller 3042 is provided below the third supporting material belt 3021, and the third cutting knife 3041 is provided on the third supporting material belt 3021.
  • the third cutter 3041 is used to cut the first-level adhesive tape 3011 to form the second-level adhesive tape 601; the fourth waste collection mechanism 305 is located on the third processing line S3
  • the waste collection station C3 recycles the waste material formed by cutting the first-level adhesive tape 3011;
  • the fifth pressing mechanism 306 is provided with a fifth pressing station C4 at the second pressing station C4 of the third processing line S3.
  • Pressure support roller 3061 is provided on one side of the third backing tape 3021 (the side away from the adhesive tape), and is used for pressing the secondary release paper 602 'and the secondary adhesive tape 601.
  • the positions of the third pressing roller 2051 and the fifth pressing support roller 3061 correspond to each other, and the second supporting material belt 2011 and the third supporting material belt 3021 are formed from the third pressing force.
  • the roller 2051 passes between the fifth pressing support roller 3061, and the third supporting material belt 3021 continues from the second pressing station C4 of the third processing line S3 to the third
  • the fourth processing line S4 transports, that is, the fourth processing line S4 continues to use the third supporting material belt 3021 provided by the third processing line S3.
  • the third processing line S3 also includes a first-level adhesive tape material roll 301 and a third backing tape material roll 302 located at the most upstream.
  • the third backing tape material roll 302 is provided with a third roll.
  • the first-level adhesive tape 3011 and the third backing material tape 3021 are pressed together by the fourth pressing mechanism 303 and closely adhere to each other, and then die-cut by the third die-cutting mechanism 304 to cut out the second-level adhesive tape 601.
  • the third support strip material roll 302 the fourth pressing mechanism 303, the third die cutting mechanism 304, the fifth pressing mechanism 306, and the fourth waste collection mechanism 305 are also The third supporting material belt 3021 can be pulled and transported.
  • the fourth processing line S4 includes a third supporting material belt 3021, a peeling support mechanism 401, a laminating mechanism 402, a fourth die-cutting mechanism 403, a fifth waste collection mechanism 404, and The second peeling mechanism 407 and the sixth scrap collection mechanism 408, the third supporting material belt 3021 of the fourth processing line S4 is used to move from the upstream to the downstream direction of the fourth processing line S4; the fourth The processing line S4 is provided with a laminating station D1, a die-cutting station D2 and a first waste collection station D3 in sequence from upstream to downstream; the fourth processing line S4 is also provided with a stripping station D4 and a second waste collection station.
  • the stripping station D4 of the fourth processing line S4 is located downstream of the die-cutting station D2 of the fourth processing line S4 and is connected to the fourth processing line S4.
  • the first waste collection station D3 of S4 is arranged in parallel; the second waste collection station D5 and the packaging station D6 of the fourth processing line S4 are both located on all sides of the fourth processing line S4.
  • the peeling support mechanism 401 Downstream of the peeling station D4, and arranged in parallel; the peeling support mechanism 401 is provided with a peeling support roller at the laminating station D1, located on one side of the third supporting material belt 3021 (as shown below); The laminating mechanism 402 applies force to the microneedle patch 603 at the laminating station D1, so that the microneedle patch 603 is completely adhered to the first-level adhesive tape; the fourth die-cutting mechanism 403 A fourth cutter 4031 and a fourth die-cutting support roller 4032 are provided at the die-cutting station D2 of the fourth processing line S4. The fourth die-cutting support roller 4032 and the fourth cutter 4031 They are respectively located on two opposite sides of the third supporting material belt 3021.
  • the fourth die-cutting support roller 4032 is provided below the third supporting material belt 3021, and the fourth cutting knife 4031 is provided on the third supporting material belt 3021.
  • the fourth cutter 4031 is used to cut the secondary release paper 602' to form a plurality of target products 600;
  • the fifth waste collection mechanism 404 is in the fourth processing line S4
  • a waste collection station D3 collects the waste material formed after the secondary release paper 602' is cut;
  • the second peeling mechanism 407 is provided with a second peeling station D4 of the fourth processing line S4.
  • the second peeling knife is arranged on the side of the third backing material strip 3021 away from the microneedle patch 603, and resists the third backing strip 3021 through its two adjacent sides, so that The third backing material belt 3021 changes from a horizontal extension direction to an oblique upward extension direction at the second stripping knife to peel off the target product 600 and the third backing material belt 3021, that is, the third The backing material strip 3021 is formed into two parts with different extension directions through the second peeling knife.
  • the included angle ⁇ between the two parts of the third backing strip 3021 is less than 90°, preferably ⁇ is less than or equal to 30°; the sixth The waste collection mechanism 408 recycles the third bottoming material strip 3021 at the second waste collection station D5 of the fourth processing line S4; the packaging station D6 is close to the second waste collection station D5 of the fourth processing line S4. Peeling station D4, the packaging station D4 is provided with a packaging box 700, and the peeled target product 600 falls into the packaging box 700. It should be understood that the non-adhesive surface of the target product 600 is exposed and can be directly placed in the packaging box 700 after being peeled off, eliminating the need for manual sampling and boxing processes.
  • the original microneedle sheet 500 is cut to form multiple microneedle patches 603 , and the microneedle patches 603 are arranged on the first backing tape 1011 in a certain manner.
  • the third backing material belt 3021 carries a secondary release paper 602', and the secondary release paper 602' is pasted with the same number of microneedle patches 603. Secondary adhesive tape 601.
  • the laminating station D1 of the fourth processing line S4 it is necessary to remove all the microneedle patches 603 after peeling off the first backing tape 1011 and the secondary adhesive on the secondary release paper 602'.
  • the stickers 601 fit one to one.
  • the microneedle patch 603 is attached to the secondary adhesive patch 601 as shown in FIG. 26 .
  • the dotted line indicates that the secondary adhesive tape 601 is not visible under the current viewing angle and is represented by a dotted line.
  • the laminating mechanism 402 includes a second blowing mechanism 4021 and a laminating support platform 4022, which are respectively provided on both sides (upper and lower) of the third base material belt 3021. .
  • the microneedle patch 603 and the secondary adhesive patch 601 are adhered together by the airflow formed by the second air blowing mechanism 4021 in the direction of the third backing material strip 3021 .
  • the second blowing mechanism 4021 can be close to or away from the fitting support platform 4022, so as to adjust the position of the second blowing mechanism 4021 to adjust the appropriate airflow beam.
  • the fitting mechanism 402 also includes a driving mechanism 4023 and a limiting rod 4024; the driving mechanism 4023 is connected to the second blowing mechanism 4021 to drive the second blowing mechanism 4021 Approach or move away from the fitting support platform 4022; the limiting rod 4024 is connected to the second blowing mechanism 4021 and the fitting supporting platform 4022 respectively; the second blowing mechanism 4021 is used to move in the direction of the limiting rod 4024.
  • the number of the limiting rods 4024 can be one or multiple symmetrically arranged ones.
  • the limiting rods 4024 can accurately define the horizontal position of the second blowing mechanism 4021 to prevent position deviation during the descent.
  • the structure of the driving mechanism 4023 is not limited, such as a linear motor, a cylinder, etc.
  • the fourth processing line S4 preferably also includes a second visual detection system 502.
  • the second visual detection system 502 detects that the third backing material tape film 3021 reaches a designated position (such as the laminating station D1).
  • the movement of the belt 3021 stops, and the driving mechanism 4023 drives the second blowing mechanism 4021 to descend close to the fitting support platform 4022.
  • the second air blowing mechanism 4021 includes an air blowing platform 4021a.
  • the air blowing platform 4021a is provided with a plurality of air outlets 4021b. The number of the air outlets 4021b is related to the micron.
  • the number of needle patches 603 is the same, and each microneedle patch 603 is blown by a corresponding air outlet 4021b, so that the entire microneedle patch 603 is attached to the secondary adhesive patch 601, that is, each microneedle patch 603 is
  • the air outlet 4021b is exactly aligned with the microneedle patch 603.
  • the aperture of the air outlet 4021b is greater than or equal to the diameter of the microneedle patch 603.
  • the aperture of the air outlet 4021b is greater than the diameter of the microneedle patch 603, so that the air blowing platform 4021a forms a sunken structure, which not only can Prevent the microneedle from being crushed, and you can also set a microneedle patch to increase the It increases the air flow utilization, avoids the influence of interfering with the air flow, and achieves better air blowing effect.
  • All the air outlets 4021b can share one airway or have independent airways.
  • the air blowing platform 4021a can be equipped with a solenoid valve that controls the opening or closing of the airway. When the solenoid valve is opened, the air blowing platform 4021a starts blowing, and stops blowing after a period of time (such as 2 to 15 seconds). 4021a rises, returns to its original position, and completes the fitting of the microneedle patch 603. After that, the third supporting material belt 3021 moves and reaches the next die-cutting station D2.
  • the setting of the second visual inspection system 502 can achieve precise fitting of the microneedle patch 603 .
  • the type of the second visual inspection system 502 is not limited. For example, an AI vision system or other commonly used visual inspection equipment can be used.
  • the laminating mechanism 402 may include a peeling and laminating pressure roller 409 corresponding to the position of the peeling support roller, the peeling and laminating pressure roller 409 and the peeling and laminating pressure roller 409.
  • Support rollers are provided on both sides (upper and lower sides) of the third backing material belt 3021 , and the peeling and laminating pressure rollers are used to press against the edge of the microneedle patch 603 .
  • the roller surface of the peeling and laminating pressure roller 409 is provided with protective material, such as dust-free foam.
  • the fourth processing line S4 also includes a second cleaning mechanism 410, located downstream of the laminating station D1, for removing the microneedle patch 603 in a non-contact manner.
  • the second cleaning mechanism 410 can remove foreign matter attached to the microneedle patch 603 due to static electricity or other reasons to ensure the cleanliness of the product.
  • the second cleaning mechanism 410 generates ionic wind for dust removal.
  • the number of the second cleaning mechanism 410 is not limited, such as one or more.
  • the third support tape 3021 is turned 180° by a number of turning rollers, and then the target product 600 is peeled off, and the target product 600 can be peeled off. Automatically peels into box 700.
  • the present invention does not limit the number of turning rollers.
  • the number of turning rollers is two, namely the first turning roller 405 and the second turning roller 406.
  • the first turning roller 405 moves the third supporting material belt 3021 turns from the horizontal direction to the vertical direction
  • the second turning roller 406 turns the third supporting material belt 3021 from the vertical direction to the horizontal direction.
  • the present invention can realize continuous and large-volume automated production of microneedle patch products, improve the processing efficiency and processing stability of microneedle patch products, and reduce processing costs. .
  • the present invention can realize parallel die-cutting of microneedle original sheets, release paper, and adhesive tape, and improve the processing efficiency of microneedle patch products.
  • the die-cut secondary adhesive tape, secondary release paper and microneedle patch are automatically assembled and laminated, and peeled off into the corresponding packaging box. Subsequent sealing and packaging are automatically completed without manual intervention, while improving processing efficiency. At the same time, it improves the stability of product processing and ensures the quality of patch-type target products.

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Abstract

一种贴片产品加工***，包括第一加工线（S1）、第二加工线（S2）、第三加工线（S3）和第四加工线（S4）；第一至第三加工线并行运行；第四加工线相对于第一至第三加工线串行运行；由第一加工线对目标物原片进行切割，形成具有预定结构的目标物贴片；由第二加工线对一级防粘纸（2021）进行切割，形成具有镂空的二级防粘纸（602'）；由第三加工线对一级粘性胶带进行切割，形成具有预定结构的二级粘性胶贴（601）；由第二加工线将二级粘性胶贴与二级防粘纸相接合，得到一级背胶料带；由第四加工线将目标物贴片与一级背胶料带相接合，再经一次切割二级防粘纸后，得到目标产品（600）。还包括一种贴片产品加工方法，该***和方法能够实现贴片产品的连续且大批量的自动化生产，提高贴片产品加工的稳定性及加工效率。

Description

贴片产品加工***及贴片产品加工方法 技术领域
本发明属于贴片产品加工技术领域，特别涉及一种贴片产品加工***及贴片产品加工方法。
背景技术
大多数治疗药物通过使用皮下注射进入人体，这是一种低成本、快速和直接的给药方式。然而患者自身却不能较容易地使用注射器，且注射器带来的疼痛和恐惧也进一步限制了患者的依从性。微针(包括尺寸为微米级的针头)上载药并经皮给药，这是解决上述问题的方法之一。
微针进入皮肤的深度通常不会达到真皮层，亦不会形成明显的疼痛感。此外，纳米微针皮内给药还有减少毒副作用，提高药物疗效，加快药物吸收等优点，是一种方便，痛感极小，安全，能自行在家中使用的产品。除此之外，微针还可以用作皮肤预处理，具有增强皮肤渗透性的能力。因此，微针具有较好的临床应用前景。
目前微针原片生产后，需要依据需求，裁切为所需形状和大小的微针贴片使用，微针贴片自身不具备粘性，需要贴合到粘性材料上使用。因此，对于微针贴片的生产包括有裁切工序、贴合工序、剥离工序和包装工序。但目前微针贴片的生产主要为人工生产或半自动半人工生产，这些生产方式还存在无法连续大批量生产，以及加工效率低，结构复杂，废料无法回收等问题。当然除了微针贴片的生产外，其他贴片产品的生产也有基本相同的问题，如硅胶片、面膜等贴片式医疗美容产品。
发明内容
本发明的目的在于提供一种贴片产品加工***及贴片产品加工方法，能够实现医用贴片产品的连续且大批量的自动化生产，提高医用贴片产品的加工稳定性及加工效率，并降低加工成本。
为实现上述目的，本发明提供了一种贴片产品加工***，其包括第一加工线、第二加工线、第三加工线和第四加工线；所述第一加工线、所述第二加工线和所述第三加工线并行运行；所述第四加工线相对于所述第一加工线、所述第二加工线和所述第三加工线串行运行；所述第一加工线用于将目标物原片，加工形成具有预定结构的目标物贴片；所述第二加工线用于将一级防粘纸，加工形成具有镂空的二级防粘纸；所述第三加工线用于将一级粘性胶带，加工形成具有预定结构的二级粘性胶贴；所述第二加工线还用于将所述二级粘性胶贴与所述二级防粘纸相接合，得到一级背胶料带；所述第四加工线用于将所述目标物贴片与所述一级背胶料带相接合，所述目标物贴片置于所述镂空中，并且所述目标物贴片的一面与所述二级粘性胶贴粘接。
在一实施方式中，所述第四加工线先被配置为先将所述目标物贴片与所述一级背胶料带相接合得到中间产品，然后将所述中间产品切割形成多个具有预定结构的目标产品；所述目标产品由所述二级粘性胶贴、三级防粘纸以及所述目标物贴片组成；所述三级防粘纸由所述二级防粘纸切割形成，所述三级防粘纸的中部具有所述镂空，所述三级防粘纸的边沿延伸超出所述二级粘性胶贴的边沿，所述二级粘性胶贴沿所述镂空的边缘设置。
在一实施方式中，所述第一加工线包括第一托底料带、第一模切机构、第一剥离机构、第一收废机构和第二收废机构，所述第一托底料带能够从所述第一加工线的上游向下游方向移动；所述第一加工线从上游至下游依次设有上料工位、模切工位、第一收废工位、剥离工位和第二收废工位；所述第一托底料带于所述上料工位与所述目标物原片接合；所述第一模切机构于所述模切工位设有第一模切支撑辊和第一切刀，所述第一模切支撑辊和所述第一切刀分别位于所述第一托底料带的两相对侧，所述第一切刀用于切割所述目标物原片以形成所述目标物贴片；所述第一收废机构于所述第一收废工位回收所述目标物原片被切割后形成的废料；所述第一剥离机构于所述剥离工位设有第一剥离刀，所述第一剥离刀设置在所述第一托底料带背离所述目标物贴片的一侧；所述第一剥离刀通过自身两相邻边顶住所述第一托底料带，使所述第一托底料带在所述第一剥离刀处由最初的水平延伸方向转变至斜向下的延伸方向，以剥离所述目标物贴片和所述第一托底料带；所述第二收废机构于所述第二收废工位回收所述第一托底料带。
在一实施方式中，所述第一加工线具有以下特征中的至少一种：
所述第一收废机构于所述第一收废工位设有第一收废支撑辊和第一收废压辊，所述第 一收废支撑辊和所述第一收废压辊分别位于所述第一托底料带的两相对侧，所述第一收废机构还设有排废胶带、送料卷筒和排料卷筒，所述送料卷筒、所述第一收废压辊和所述排料卷筒依次通过所述排废胶带连接，所述排废胶带由所述送料卷筒送出，并经过所述第一收废压辊的压抵后粘接所述废料，粘接废料的所述排废胶带由所述排料卷筒回收；
所述第二收废机构于所述第二收废工位设有卷绕所述第一托底料带的第一收废卷筒；
所述第一加工线还包括能够张紧所述第一托底料带的第一压合机构，所述第一加工线还设有压合工位，所述压合工位设于所述上料工位的上游，所述第一压合机构于所述压合工位设有第一压合支撑辊和第一压合压辊，所述第一压合支撑辊和所述第一压合压辊分别位于所述第一托底料带的两相对侧；以及，
所述第一加工线还包括设于最上游的第一托底料带材料卷，所述第一托底料带材料卷设有成卷的第一托底料带。
在一实施方式中，所述第一加工线还包括辅助贴合机构，用于将所述目标物原片与所述第一托底料带相贴合，所述第一加工线还设有辅助贴合工位，所述辅助贴合工位设于所述上料工位和所述模切工位之间，所述第一托底料带自所述上料平台下方输送，并由下而上穿过所述上料平台的出料侧和所述辅助贴合机构之间。
在一实施方式中，所述辅助贴合机构设置为以下特征中的至少一种：
所述辅助贴合机构包括第一辅助压合机构，所述第一辅助压合机构包括设于所述第一托底料带两相对侧的压板和贴合板；所述压板能够靠近或远离所述贴合板，所述压板于靠近所述贴合板时能够压抵所述目标物原片的边缘，使所述目标物原片的边缘与所述第一托底料带贴合；
所述辅助贴合机构包括第一吹气机构，用于向所述目标物原片吹气，使所述目标物原片与所述第一托底料带贴合；以及，
所述辅助贴合机构包括第二辅助压合机构，所述第二辅助压合机构包括设于所述第一托底料带两相对侧的第一辅助贴合压辊和第一辅助贴合支撑辊，所述第一辅助贴合压辊能够靠近或远离所述第一辅助贴合支撑辊，所述第一辅助贴合压辊于靠近所述第一辅助贴合支撑辊时能够压抵所述目标物原片的边缘，使所述目标物原片的边缘与所述第一托底料带贴合，所述第一辅助贴合压辊的辊面包绕有保护材料。
在一实施方式中，所述第一加工线包括用于放置所述目标物原片的上料平台，所述上料平台能够吸附所述目标物原片，和/或，所述上料平台自身能够移动和/或转动，以将所述目标物原片的一部分推送出所述上料平台。
在一实施方式中，所述上料平台设有多个吸附孔，且所述上料平台的内部形成有与所述吸附孔连通的负压腔，其中所述上料平台具有具有以下特征中的至少一种：
多个所述吸附孔沿所述目标物原片的出料方向由密到疏或由疏到密分布；
多个所述吸附孔沿垂直于所述目标物原片的出料方向由密到疏或由疏到密分布；
多个所述吸附孔的分布密度为中间疏、边缘密或中间密、边缘疏；
多个所述吸附孔的孔径沿所述目标物原片的出料方向由大到小或由小到大分布；
多个所述吸附孔的孔径沿垂直于所述目标物原片的出料方向由大到小或由小到大分布；
多个所述吸附孔的孔径为中间部分的孔径大、边缘部分的孔径小或中间部分的孔径小、边缘部分的孔径大。
在一实施方式中，所述上料平台沿所述目标物原片的出料方向形成多排吸附结构，每排所述吸附结构包括沿垂直于所述出料方向依次设置的多个所述吸附孔，多排所述吸附结构形成多行多列矩阵；一部分相邻行中的所述吸附孔不共用同一个负压腔，和/或，一部分相邻列中的所述吸附孔不共用同一个负压腔。
在一实施方式中，所述上料平台设置有多个独立设置的所述负压腔，所述负压腔设置为以下特征中的一种：
多个所述负压腔沿所述目标物原片的出料方向依次布置；
多个所述负压腔沿垂直于所述目标物原片的出料方向依次布置；
多个所述负压腔中的一些分布在所述上料平台的中间，另一些分布在所述上料平台的边缘。
在一实施方式中，所述上料平台为仿形传送带，所述仿形传送带沿输送方向依次设置多个隔板，相邻所述隔板之间为一传送节段，每个所述传送节段用于放置一个所述目标物原片。
在一实施方式中，所述第一加工线还包括辅助贴合机构，用于将所述目标物原片与第 一托底料带相贴合，所述第一托底料带用于输送所述目标物原片；所述第一加工线还设有辅助贴合工位，所述辅助贴合工位设于所述上料工位和所述模切工位之间；所述第一托底料带自所述仿形传送带下方输送，并由下而上穿过所述仿形传送带的出料侧和所述辅助贴合机构之间；其中每个所述隔板突出所述仿形传送带的传送面的高度小于所述上料平台的出料侧与所述辅助贴合机构之间的间隙宽度。
在一实施方式中，所述上料平台上设有限位挡板，所述限位挡板用于阻止所述目标物原片朝出料方向以外的方向移动。
在一实施方式中，所述限位挡板的大小可调节，和/或，所述限位挡板的至少部分结构能够相对于所述上料平台移动，以将所述目标物原片的一部分推送出所述上料平台。
在一实施方式中，所述限位挡板包括两个侧挡板和一个推板，两个所述侧挡板设置在所述推板的两相对侧，所述推板与两个所述侧挡板可移动地连接，或者，所述限位挡板为一体式弯形推板，所述弯形推板包绕并用于推动所述目标物原片。
在一实施方式中，所述第二加工线包括第二托底料带、第二压合机构、第二模切机构、第三压合机构和第三收废机构，所述第二托底料带用于从所述第二加工线的上游向下游方向运动；所述第二加工线从上游至下游依次设有第一压合工位、模切工位、第二压合工位和收废工位；所述第二压合机构于所述第一压合工位设有第二压合支撑辊和第二压合压辊，所述第二压合支撑辊和所述第二压合压辊分别位于所述第二托底料带的两相对侧，以使所述第二托底料带与所述一级防粘纸相接合；所述第二模切机构于所述模切工位设有第二模切支撑辊和第二切刀，所述第二模切支撑辊和所述第二切刀分别位于所述第二托底料带的两相对侧，所述第二切刀用于切割所述一级防粘纸以形成所述二级防粘纸；所述第三压合机构于所述第二压合工位设有第三压合压辊，所述第三压合压辊设于所述第二托底料带的一侧，以使所述二级防粘纸和所述二级粘性胶贴相接合；所述第三收废机构于所述收废工位通过所述第二托底料带回收所述一级防粘纸被切割后形成对应于所述镂空的废料，并使所述第二托底料带于所述第二压合工位与所述二级防粘纸分离。
在一实施方式中，所述第二加工线具有以下特征中的至少一种：
所述第三收废机构于所述收废工位设有卷绕所述第二托底料带的第二收废卷筒；
所述第二加工线还包括设于最上游的第二托底料带材料卷和一级防粘纸材料卷，所述第二托底料带材料卷设有成卷的第二托底料带，所述一级防粘纸材料卷设有成卷的一级防粘纸，所述第二托底料带材料卷和所述一级防粘纸材料卷相互独立设置。
在一实施方式中，所述第三加工线包括第三托底料带、第四压合机构、第三模切机构、第四收废机构和第五压合机构，所述第三托底料带用于从所述第三加工线的上游向下游方向运动；
所述第三加工线从上游至下游依次设有第一压合工位、模切工位和收废工位，所述第三加工线还设有第二压合工位，所述第二压合工位设于所述模切工位的下游，并与所述收废工位并行设置；
所述第四压合机构于所述第一压合工位设有第四压合支撑辊和第四压合压辊，所述第四压合支撑辊和所述第四压合压辊分别位于所述第三托底料带的两相对侧，以使所述第三托底料带与所述一级粘性胶带相接合；
所述第三模切机构于所述模切工位设有第三模切支撑辊和第三切刀，所述第三模切支撑辊和所述第三切刀分别位于所述第三托底料带的两相对侧，所述第三切刀用于切割所述一级粘性胶带以形成所述二级粘性胶贴；
所述第四收废机构于所述收废工位回收所述一级粘性胶带切割形成的废料；
所述第五压合机构于所述第二压合工位设有第五压合支撑辊，所述第五压合支撑辊设于所述第三托底料带的一侧，以使所述二级防粘纸和所述二级粘性胶贴相结合。
在一实施方式中，所述第三压合机构于所述第二加工线的第二压合工位设有第三压合辊，所述第三压合压辊设于所述第二托底料带的一侧，所述第五压合支撑辊设于所述第二托底料带的另一侧，所述第三压合压辊和所述第五压合支撑辊的位置相对应；所述第二加工线的第二托底料带和所述第三托底料带从所述第三压合压辊和所述第五压合支撑辊之间穿过，且所述第四加工线和所述第三加工线共用所述第三托底料带，如所述第三托底料带自所述第三加工线的所述第二压合工位继续向所述第四加工线输送。
在一实施方式中，所述第三加工线还包括设于最上游的一级粘性胶带材料卷和第三托底料带材料卷，所述第三托底料带材料卷设有成卷的第三托底料带，所述一级粘性胶带材料卷设有成卷的一级粘性胶带，所述第三托底料带材料卷和所述一级粘性胶带材料卷相互独立设置。
在一实施方式中，所述第四加工线包括第三托底料带、剥离支撑机构、贴合机构、第四模切机构、第五收废机构、第二剥离机构和第六收废机构，所述第三托底料带用于从所述第四加工线的上游向下游方向运动；所述第四加工线从上游至下游依次设有贴合工位、模切工位和第一收废工位；所述第四加工线还设有剥离工位、第二收废工位和包装工位；所述剥离工位设于所述模切工位的下游，并与所述第一收废工位并行设置；所述第二收废工位和所述包装工位均设于所述剥离工位的下游且并行设置；所述剥离支撑机构于所述贴合工位以及所述第三托底料带的一侧设有剥离支撑辊；所述贴合机构于所述贴合工位向所述目标物贴片施加作用力，以使所述目标物贴片与所述一级背胶料带接合；所述第四模切机构于所述模切工位设有第四模切支撑辊和第四切刀，所述第四模切支撑辊和所述第四切刀分别位于所述第三托底料带的两相对侧，所述第四切刀用于切割所述二级防粘纸以形成多个所述目标产品；所述第五收废机构于所述第一收废工位回收所述二级防粘纸被切割后形成的废料；所述第二剥离机构于所述剥离工位设有第二剥离刀，所述第二剥离刀设置在所述第三托底料带背离所述目标产品的一侧；所述第二剥离刀通过自身两相邻边顶住所述第三托底料带，使所述第三托底料带在所述第二剥离刀处由最初的水平延伸方向转变至斜向上的延伸方向，以剥离所述目标产品和所述第三托底料带；所述第六收废机构于所述第二收废工位回收所述第三托底料带；所述包装工位靠近所述剥离工位设置，所述包装工位设有包装盒，剥离后的所述目标产品自动掉入所述包装盒。
在一实施方式中，所述贴合机构包括与所述剥离支撑辊位置相对应的剥离贴合压辊，所述剥离贴合压辊和所述剥离支撑辊设于所述第三托底料带的两相对侧，所述剥离贴合压辊用于压抵所述目标物贴片的边缘，使所述目标物贴片与所述二级粘性胶贴接合，所述剥离贴合压辊的辊面包绕有可变形的保护结构。
在一实施方式中，所述贴合机构包括第二吹气机构和贴合支撑平台，所述第二吹气机构和所述贴合支撑平台分别设置在所述第三托底料带的两相对侧；所述第二吹气机构能够靠近或远离所述贴合支撑平台；所述第二吹气机构于靠近所述贴合支撑平台时用于向所述目标物贴片吹气，使所述目标物贴片与所述二级粘性胶贴接合。
在一实施方式中，所述目标物贴片的数量为多个，所述第二吹气机构包括吹气平台，所述吹气平台设有多个出气孔，所述出气孔的数量和位置与所述目标物贴片的数量及位置相对应，每个所述目标物贴片由对应的一个所述出气孔对其吹气，所述出气孔的孔径大于所述目标物贴片的直径，所述吹气平台于靠近所述贴合支撑平台时，所述出气孔套设所述目标物贴片进行吹气。
在一实施方式中，所述第四加工线还包括与控制***通信连接的第二视觉检测***，所述控制***用于根据所述第二视觉检测***的视觉检测信息控制所述贴合机构的状态。
为实现上述目的，本发明还提供了一种贴片产品加工方法，所述加工方法由任一项所述的贴片产品加工***所实施。
在本发明所公开的贴片产品加工***及贴片加工方法中，所述贴片产品加工***包括：第一加工线、第二加工线、第三加工线和第四加工线；所述第一加工线、所述第二加工线和所述第三加工线并行运行；所述第四加工线相对于所述第一加工线、所述第二加工线和所述第三加工线串行运行；所述第一加工线用于将目标物原片，加工形成具有预定结构的目标物贴片；所述第二加工线用于将一级防粘纸，加工形成具有镂空的二级防粘纸；所述第三加工线用于将一级粘性胶带，加工形成具有预定结构的二级粘性胶贴；所述第二加工线还用于将所述二级粘性胶贴与所述二级防粘纸相接合，得到一级背胶料带；所述第四加工线用于将所述目标物贴片与所述一级背胶料带相接合，所述目标物贴片置于所述镂空中，并且所述目标物贴片的一面与所述二级粘性胶贴粘接。如此配置时，使本发明能够实现贴片式目标产品的连续且大批量的自动化生产，提高目标产品的加工效率和加工稳定性，降低加工成本。本发明能够实现目标物原片、防粘纸、粘性胶带的并行模切，提高贴片式目标产品的加工效率。此外，完成模切的二级粘性胶贴、二级防粘纸和目标物贴片自行汇聚贴合，并剥离至相应包装盒中，自动完成后续封口包装，无需人工干预，在提高加工效率的同时，提升了产品加工的稳定性，确保了贴片式目标产品的质量。
附图说明
本领域的普通技术人员将会理解，提供的附图用于更好地理解本发明，而不对本发明的范围构成任何限定。其中：
图1为本发明一优选实施例所提供的微针贴片产品加工流程图；
图2为本发明一优选实施例所提供的贴片产品加工***的视图，其中箭头指示物料的 输送方向；
图3a为本发明一优选实施例所提供的微针贴片产品的组装视图；
图3b为本发明一优选实施例所提供的微针贴片产品的分解视图；
图3c为本发明一优选实施例所提供的微针贴片产品的剖面视图；
图4为本发明一优选实施例所提供的对微针贴片产品进行包装的视图；
图5为本发明一优选实施例所提供的采用排废胶带回收微针原片切割废料的视图；
图6为本发明一优选实施例所提供的对中间产品进行切割后形成多个目标产品的视图；
图7为本发明一优选实施例所提供的整个连排目标产品的视图；
图8为本发明一优选实施例所提供的微针原片于上料平台上放置时，微针原片的一部分伸出上料平台的出料侧以搭于第一托底料带上的视图；
图9为本发明一优选实施例所提供的具有吸附孔的上料平台的立体视图；
图10为图9中上料平台的断面视图；
图11为本发明一优选实施例所提供的具有吸附孔的上料平台以及于上料平台上设置限位挡板的视图；
图12为本发明一优选实施例所提供的吸附孔沿出料侧方向由疏到密分布的视图；
图13为本发明一优选实施例所提供的吸附孔沿出料侧方向孔径由小到大分布的视图；
图14为本发明一优选实施例所提供的每排吸附结构沿出料侧方向单独设置负压腔的视图；
图15为本发明一优选实施例所提供的仿形传送带形成上料平台的视图；
图16为本发明一优选实施例所提供的于上料平台的出料侧设置第一辅助压合机构和第一吹气机构的视图；
图17为本发明一优选实施例所提供的上料辊轴形成上料平台的视图；
图18为本发明一优选实施例所提供的部分可移动的限位挡板的视图；
图19为本发明一优选实施例所提供的整体可移动的限位挡板的视图；
图20至图22分别为本发明一优选实施例所提供的压板的形状与微针原片上暴露区域的形状匹配的视图；
图23和图24分别为本发明一优选实施例所提供的第一吹气机构所设置的出气孔的分布视图；
图25为本发明一优选实施例所提供的采用第二辅助压合机构对出料侧的微针原片进行压合，以及采用第一清洁机构对出料侧的微针原片进行除尘的视图；
图26为本发明一优选实施例所提供的对微针原片进行切割而在第一托底料带上形成多个微针贴片的视图；
图27为本发明一优选实施例所提供的由第三托底料带承托一级背胶料带的视图，其中二级粘性胶贴与微针贴片的数量和位置对应；
图28为本发明一优选实施例所提供的由第三托底料带承托多个目标产品的视图，其中微针贴片与二级粘性胶贴一一对应地粘接；
图29为本发明一优选实施例所提供的贴合机构的视图；
图30为本发明一优选实施例所提供的第二吹气机构上吹气平台的视图；
图31为本发明一优选实施例所提供的采用剥离贴合压辊压合微针贴片与二级粘性胶贴，以及采用第二清洁机构对微针贴片进行除尘的视图。
[附图标记说明如下]：
500-微针原片；600、600’-目标产品；601-二级粘性胶贴；602-三级防粘纸；603-微针贴片；602’-二级防粘纸；700-包装盒；800-盒盖；S1-第一加工线；A1-第一加工线的上料工位；A2-第一加工线的模切工位；A3-第一加工线的第一收废工位；A4-第一加工线的剥离工位；A5-第一加工线的第二收废工位；A6-第一加工线的压合工位；A7-辅助贴合工位；101-第一托底料带材料卷；1011-第一托底料带；102-第一压合机构；1021-第一压合压辊；1022-第一压合支撑辊；103-上料平台；103a-仿形传送带；103b-暴露区域；1031-吸附孔；1032-隔板；1033-上料辊轴；1034-负压腔；S-出料侧；104-第一模切机构；1041-第一切刀；1042-第一模切支撑辊；105-第一收废机构；1051-第一收废压辊；1052-第一收废支撑辊；1053-送料卷筒；1054-排料卷筒；1055-排废胶带；106-第一剥离机构；107-第二收废机构；108-限位挡板；109-第一辅助压合机构；1091-压板；1092-贴合板；110-第一吹气机构；1101-第一吹气机构的出气孔；111-第二辅助压合机构；1111-第一辅助贴合压辊；1112-第一辅助贴合支撑辊；112-第一清洁机构；S2-第二加工线；B1-第二加工线的第一压合工 位；B2-第二加工线的模切工位；B3-第二加工线的第二压合工位；B4-第二加工线的收废工位；201-第二托底料带材料卷；2011-第二托底料带；202-一级防粘纸材料卷；2021-一级防粘纸；203-第二压合机构；2031-第二压合压辊；2032-第二压合支撑辊；204-第二模切机构；2041-第二模切支撑辊；2042-第二切刀；205-第三压合机构；2051-第三压合压辊；206-第三收废料机构；S3-第三加工线；C1-第三加工线的第一压合工位；C2-第三加工线的模切工位；C3-第三加工线的收废工位；C4-第三加工线的第二压合工位；301-一级粘性胶带材料卷；3011-一级粘性胶带；302-第三托底料带材料卷；3021-第三托底料带；303-第四压合机构；3031-第四压合压辊；3032-第四压合支撑辊；304-第三模切机构；3041-第三切刀；3042-第三模切支撑辊；305-第四收废料机构；306-第五压合机构；3061-第五压合支撑辊；S4-第四加工线；D1-第四加工线的贴合工位；D2-第四加工线的模切工位；D3-第四加工线的第一收废工位；D4-第四加工线的剥离工位；D5-第四加工线的第二收废工位；D6-第四加工线的包装工位；401-剥离支撑机构；402-贴合机构；4021-第二吹气机构；4021a-吹气平台；4021b-第二吹气机构的出气孔；4022-贴合支撑平台；4023-驱动机构；4024-限位杆；403-第四模切机构；4031-第四切刀；4032-第四模切支撑辊；404-第五收废料机构；405-第一转向辊；406-第二转向辊；407-第二剥离机构；408-第六收废料机构；409-剥离贴合压辊；410-第二清洁机构；501-第一视觉检测***；502-第二视觉检测***。
具体实施方式
下面将结合示意图对本发明进行更详细的描述，其中表示了本发明的优选实施例，应该理解本领域技术人员可以修改在此描述的本发明，而仍然实现本发明的有利效果。因此，下列描述应当被理解为对于本领域技术人员的广泛知道，而并不作为对本发明的限制。
为了清楚，不描述实际实施例的全部特征。在下列描述中，不详细描述公知的功能和结构，因为它们会使本发明由于不必要的细节而混乱。应当认为在任何实际实施例的开发中，必须做出大量实施细节以实现开发者的特定目标，例如按照有关***或有关商业的限制，由一个实施例改变为另一个实施例。另外，应当认为这种开发工作可能是复杂和耗费时间的，但是对于本领域技术人员来说仅仅是常规工作。在下列段落中参照附图以举例方式更具体地描述本发明。根据下面说明，本发明的优点和特征将更清楚。需说明的是，附图均采用非常简化的形式且均使用非精准的比例，仅用以方便、明晰地辅助说明本发明实施例的目的。
此外，在本申请使用的术语是仅仅出于描述特定实施方式的目的，而非旨在限制本申请。在本申请中所使用的单数形式的“一种”、“所述”和“该”也旨在包括多数形式，除非上下文清楚地表示其他含义。应当理解，本申请说明书中使用的“第一”、“第二”、“第三”、“第四”、“第五”、“第六”以及类似的词语并不表示任何顺序、数量或者重要性，而只是用来区分不同的组成部件。同样，“一个”或者“一”等类似词语也不表示数量限制，而是表示存在至少一个；“多个”表示两个及两个以上的数量。除非另行指出，“前部”、“后部”、“下部”和/或“上部”等类似词语只是为了便于说明，而并非限于一个位置或者一种空间定向。“包括”或者“包含”等类似词语意指出现在“包括”或者“包含”前面的元件或者物件涵盖出现在“包括”或者“包含”后面列举的元件或者物件及其等同，并不排除其他元件或者物件。还应当理解，本申请说明书中使用的“若干”表示数量不确定的含义。本文中，“前方”是相对于“后方”而言的；“前方”是指物料先到达的位置，“后方”相对于“前方”为后收到物料的位置，“前后”是沿着物料的传输方向的水平方向，“左右”是垂直于物料的传输方向的水平方向；“向前”是指物料由前方向后方输送的方向。如图2中，垂直于纸面的方向为左右方向，平行于纸面的方向为前后方向。所应理解，本文中的物料可指未加工的产品，也可指加工后的产品。此外，术语“上游”是相对于“下游”而言的；“上游”相对于“下游”通常是先加工或先接收物料的位置；“下游”相对于“上游”通常是后加工或后接收物料的位置。另外，需理解，在本申请使用的所有托底料带均为低粘度的托底膜，例如为PET硅胶膜。
下面结合附图和优选实施例，对本申请进行详细说明，应理解，以下描述中，虽以微针贴片的加工为示意进行说明，但本领域技术人员可以理解，本发明还可以实现其他贴片式目标产品的加工，如硅胶片或面膜等贴片产品的加工。此外，在不冲突的情况下，下述的实施方式及实施方式中的特征可以相互补充或相互组合。
本发明公开一种贴片产品加工方法，包括：
由第一加工线对目标物原片进行加工，形成具有预定结构的目标物贴片；
由第二加工线对一级防粘纸进行加工，形成具有镂空的二级防粘纸；
由第三加工线对一级粘性胶带进行加工，形成具有预定结构的二级粘性胶贴；
由所述第二加工线将所述二级粘性胶贴与所述二级防粘纸相接合，得到一级背胶料带；
由第四加工线将所述目标物贴片与所述一级背胶料带相接合，所述目标物贴片置于所述镂空中，并且所述目标物贴片的一面与所述二级粘性胶贴粘接。
以微针贴片的加工为例，图1为本发明一优选实施例所公开的微针贴片产品的加工方法，其包括第一至第四加工流程。
具体地，由第一加工线S1实施第一加工流程，以对微针原片进行加工，形成具有预定结构的微针贴片，具体包括：
步骤S11，微针原片(即目标物原片)上料；
步骤S12，切割微针原片，形成具有预定结构(包括预定形状和大小)的微针贴片(即目标物贴片)；所述微针贴片的数量一般为多个；
步骤S13，剥离微针贴片；具体地，将微针贴片与第一托底料带剥离。
由第二加工线S2实施第二加工流程，以对一级防粘纸进行加工，形成具有镂空的二级防粘纸，还将所述二级粘性胶贴与所述二级防粘纸相接合，得到一级背胶料带，具体包括：
步骤S21，一级防粘纸上料；
步骤S22，切割一级防粘纸，形成具有镂空的二级防粘纸；所述二级防粘纸上镂空的数量及位置与微针贴片的数量及位置一一对应；
步骤S23，剥离二级防粘纸；在此，一级防粘纸被切割后形成有镂空的废料，因此，需要将镂空的废料和第一托底料带均与二级防粘纸剥离，便于剥离后的二级防粘纸与步骤S24中的二级粘性胶贴接合；
步骤S24，二级防粘纸与二级粘性胶贴接合；粘性胶贴可采用水凝胶、水胶体、无纺布胶带等粘性材料。
以上步骤S23和步骤S24可以同时进行，或者步骤S23先执行，步骤S24后执行。需知，防粘纸选用离型纸或其他具有类似性能的防粘纸即可。
由第三加工线S3实施第三加工流程，以对一级粘性胶带进行加工，形成具有预定结构的二级粘性胶贴，具体包括：
步骤S31，一级粘性胶带上料；
步骤S32，切割一级粘性胶带，形成具有预定结构(预定形状和大小)的二级粘性胶贴；所述二级粘性胶贴的数量及位置与微针贴片的数量及位置一一对应；
步骤S32之后，执行步骤S24。
在上述步骤S24中，二级防粘纸与二级粘性胶贴接合后，得到一级背胶料带。所述一级背胶料带中，二级防粘纸接合在二级粘性胶贴的背胶面，并且镂空处裸露出二级粘性胶贴以接合微针贴片。本实施例中，一张大的二级防粘纸具有多个镂空，在每个镂空处覆盖有一个二级粘性胶贴，二级粘性胶贴的面积大于镂空的面积。
由第四加工线S4实施第四加工流程，具体包括步骤S41，贴合微针贴片与一级背胶料带，以得到包含微针贴片的目标产品。
在一实施方式中，贴合微针贴片与一级背胶料带后，得到一整张连排的目标产品，此时，连排目标产品由一整张二级防粘纸、多个二级粘性胶贴和多个目标物贴片组成。
在另一实施方式中，微针贴片与一级背胶料带接合后，得到中间产品，进一步由第四加工线S4切割中间产品中的二级防粘纸，得到多个目标产品，此时，每个目标产品由二级粘性胶贴、三级防粘纸以及目标物贴片组成，所述三级防粘纸由所述二级防粘纸切割形成，所述三级防粘纸的中部具有所述镂空，所述目标物贴片***所述镂空中，并且所述目标物贴片的一面与所述二级粘性胶贴粘接。
所述微针贴片的一面(微针面)设有多根微针，所述微针贴片的另一面(非微针面)粘附在二级粘性胶贴上，多个微针贴片与多个二级粘性胶贴一一对应地粘接。所述微针贴片包括基底和形成于所述基体上的多根微针，所有微针设置在基底的中心区域，在中心区域的***形成边缘区域(即无针区)。在实践中，所述基底和微针可以整体或一体式制作而成，或者两者分体制作而成。
在一可选方式中，所述第四加工流程还包括：
步骤S42，贴合微针贴片与一级背胶料带后，得到中间产品，再将所述中间产品切割形成多个目标产品。具体地，切割中间产品上的二级防粘纸，以得到多个目标产品。
所述第四加工流程还包括：
步骤S43，剥离所述目标产品，剥离后的目标产品可自动装入包装盒。这里，剥离目标产品和承托目标产品的第三托底料带，目标产品与第三托底料带剥离后自动落入包装盒。
进一步地，所述第四加工流程还包括：
步骤S44，装入包装盒后，由封口机对包装盒进行自动封口。
在一具体实施例中，所述包装盒为吸塑盒，对吸塑盒进行塑封封口。
参阅图3a～图3c以及图6，在一实施方式中，可加工多个目标产品600，每个目标产品600由二级粘性胶贴601、三级防粘纸602和微针贴片603组成。所述三级防粘纸602由所述二级防粘纸切割形成，并且所述三级防粘纸602的中部具有镂空，所述镂空的形状一般与微针贴片603的形状对应；所述微针贴片603置于所述镂空中，并且所述微针贴片603的一面与二级粘性胶贴601粘接。所有目标产品600具有相同的形状和大小。三级防粘纸602的大小与二级粘性胶贴601的大小可以相同，使贴合后，三级防粘纸602的边沿与二级粘性胶贴601几乎重合。或者，三级防粘纸602的边沿延伸超过二级粘性胶贴601的边沿，以在二级粘性胶贴601的***形成裸露的三级防粘纸602，所述二级粘性胶贴601沿所述镂空的边缘设置。考虑到三级防粘纸602若尺寸太小，使用者操作不方便，因此，三级防粘纸602的尺寸大于二级粘性胶贴601的尺寸，使用者可以直接撕二级粘性胶贴601***多出的三级防粘纸602，就可以快速方便地撕掉三级防粘纸602，使操作更加方便。以离型纸和水胶体为例，离型纸用于保护暴露于微针贴片603外的水胶体胶面，免于因受空气或外物接触而造成的污染或粘接力下降，使用时，将离型纸沿目标产品600的中部易撕线撕开，取下离型纸后，即可将水胶体贴在皮肤上，适当按压即可，不仅使用方便，而且避免了因胶面裸露或污染造成粘接力下降的问题。
参阅图7，在另一实施方式中，可加工出连排的目标产品600’，即由二级防粘纸602’、多个二级粘性胶贴601和多个微针贴片603组成，二级粘性胶贴601与微针贴片603一一对应地粘接。
图4为本发明对目标产品600进行包装的一具体示范例。如图4所示，在一实施方式中，所述第四加工线S4可将剥离后的目标产品600自动装入包装盒700中，最后对包装盒700进行封口即可。包装盒700可包括盒体和盒盖800，目标产品600置于盒体中，盒盖800与盒体盖合后，由封口机进行塑封。应理解，由于目标产品600的无胶面暴露，因此，目标产品600与第三托底料带剥离后可直接放置在包装盒700中，避免了人工手动用取样器取样，如利用无纺布胶带的粘性，粘起目标产品，再将无纺布胶带贴合在包装盒的指定取样，有效地节省了加工时间，加工效率高。优选地，所述包装盒700的内腔形状与目标产品600的形状相匹配，以较好的固定目标产品600，有效地防止目标产品600的晃动，降低损坏风险。
参阅图1和图2，本发明实施例还提供一种实施上述贴片产品加工方法的贴片产品加工***，所述贴片产品加工***包括第一加工线S1、第二加工线S2、第三加工线S3和第四加工线S4；所述第一加工线S1、所述第二加工线S2和所述第三加工线S3并行运行；所述第四加工线S4相对于所述第一加工线S1、所述第二加工线S2及所述第三加工线S3串行运行；所述第一加工线S1用于将微针原片500，加工形成具有预定结构(形状和大小)的微针贴片603；所述第二加工线S2用于将一级防粘纸，加工形成具有镂空的二级防粘纸602’；所述第三加工线S3用于将一级粘性胶带，加工形成具有预定结构(形状和大小)的二级粘性胶贴601；所述第二加工线S2还用于将所述二级粘性胶贴601与所述二级防粘纸602’相接合，得到一级背胶料带；所述第四加工线S4用于将微针贴片603与所述一级背胶料带相接合，得到目标产品600或600’。
如此配置时，所述贴片产品加工***能够实现微针原片、防粘纸、粘性胶带的并行模切，提高微针贴片的加工效率。此外，完成模切的二级粘性胶贴、二级防粘纸和微针贴片自行汇聚贴合，并剥离至相应包装盒中，自动完成后续封口包装，无需人工干预，在提高加工效率的同时，提升了产品生产的稳定性，确保了微针贴片产品的质量。
在一实施方式中，所述第四加工线S4被配置为先将微针贴片603与所述一级背胶料带相接合得到中间产品，然后将所述中间产品切割形成多个目标产品600。然而在本申请的其他实施例中，可取消中间产品，无需对二级防粘纸进行再次切割，此时，第四加工线S4可直接加工得到连排的目标产品600’。
参阅图2，在一实施方式中，所述第一加工线S1包括第一托底料带1011、第一模切机构104、第一剥离机构106、第一收废机构105和第二收废机构107，所述第一托底料带1011能够从所述第一加工线S1的上游向下游方向移动；所述第一加工线S1从上游至下游 依次设有上料工位A1、模切工位A2、第一收废工位A3、剥离工位A4和第二收废工位A5；所述第一托底料带1011于所述上料工位A1与微针原片500接合，此后，第一托底料带1011便可拖动微针原片500向下游输送；所述第一模切机构104于所述模切工位A2设有第一切刀1041和第一模切支撑辊1042，所述第一模切支撑辊1042和所述第一切刀1041分别位于所述第一托底料带1011的两相对侧，如第一模切支撑辊1042在第一托底料带1011的下方，第一切刀1041在第一托底料带1011的上方，所述第一切刀1041用于切割微针原片500以形成微针贴片603；所述第一收废机构105于所述第一收废工位A3回收微针原片500被切割后形成的废料；所述第一剥离机构106于所述剥离工位A4设有第一剥离刀，所述第一剥离刀设置在所述第一托底料带1011背离微针贴片603的一侧；所述第一剥离刀通过自身的两相邻边顶住所述第一托底料带1011，使所述第一托底料带1011在所述第一剥离刀处由最初的水平延伸方向转变至斜向下的延伸方向，从而剥离微针贴片603和所述第一托底料带1011，即第一托底料带1011通过第一剥离刀形成延伸方向不同的两部分，第一托底料带1011的两部分之间的夹角α小于90°，优选α小于或等于30°；所述第二收废机构107于所述第二收废工位A5回收所述第一托底料带1011。如此配置后，通过第一加工线S1能够实现微针原片500的自动化模切和剥离，还实现了废料的自动化回收，此外，微针原片的上料也可自动化，整个过程无需人工干预，加工效率高，而且加工稳定性好。
在一实施方式中，所述第一收废机构105于所述第一收废工位A3设有第一收废压辊1051和第一收废支撑辊1052，所述第一收废支撑辊1052和所述第一收废压辊1051分别位于所述第一托底料带1011的两相对侧，如第一收废支撑辊1052位于第一托底料带1011的下方，第一收废压辊1051位于第一托底料带1011的上方；所述第一收废机构105还设有排废胶带1055、送料卷筒1053和排料卷筒1054；所述送料卷筒1053、所述第一收废压辊1051和所述排料卷筒1054依次通过所述排废胶带1055连接；所述排废胶带1055由所述送料卷筒1053送出，并经过所述第一收废压辊1051的压抵后粘接微针原片500切割形成的废料，粘接废料的所述排废胶带1055由所述排料卷筒1054回收。在一实施方式中，所述第二收废机构107于所述第二收废工位A5设有卷绕所述第一托底料带1011的第一收废卷筒。如此配置时，可以快速有效地实现废料的分离，排废效率高，而且不容易损伤微针贴片603，风险低。还应理解，由于将排废胶带1055的上料设置在模切之后，减小了排废胶带1055的上料对模切的不利影响，尤其还增加了第一收废压辊1051，使第一收废压辊1051与第一收废支撑辊1052配合，进一步降低了排废胶带1055对模切操作的不利影响，确保了模切精度。
参阅图5，所述第一收废压辊1051用于将排废胶带1055压抵在微针原片500的边缘部分，以避免对微针原片500的中间部分的微针结构造成破坏。为了保护切好的微针原片500不被破坏，所述第一收废压辊1051优选为哑铃状，能够同时将两股排废胶带1055分别压合在微针原片500的边缘部分，而不触及切好的微针原片500的微针区域。所述第一收废压辊1051的左右压轮之间的间距可调或固定，如果间距可调，可适应不同大小的微针原片。
返回参阅图2，在一实施方式中，所述第一加工线S1还包括能够张紧所述第一托底料带1011的第一压合机构102；所述第一加工线S1还设有压合工位A6，所述压合工位A6设于所述上料工位A1的上游；所述第一压合机构102于所述压合工位A6设有第一压合支撑辊1022和第一压合压辊1021，所述第一压合支撑辊1022和所述第一压合压辊1021分别位于所述第一托底料带1011的两相对侧，如第一压合支撑辊1022在第一托底料带1011的下方，第一压合压辊1021在第一托底料带1011的上方。第一压合机构102的设置，能够更进一步地拉直绷紧第一托底料带1011，确保加工精度。第一压合机构102的数量可以是一个或多个并排设置。
在一实施方式中，所述第一加工线S1还包括设于最上游的第一托底料带材料卷101，所述第一托底料带材料卷101设有成卷的第一托底料带1011。所述第一托底料带材料卷101除了提供第一托底料带1011外，还能够牵引、输送、张紧第一托底料带1011。
需理解，在第一加工线S1中，可利用第一托底料带材料卷101、第一压合机构102、第一模切机构104、第一收废机构105和第二收废机构107达到牵引和输送第一托底料带1011的作用，其中第一剥离机构106还能实现第一托底料带1011的转向输送。
在一实施方式中，所述第一加工线S1还包括用于放置微针原片500的上料平台103，所述上料平台103设于所述上料工位A1。
如图8至图19所示，所述微针原片500于所述上料平台103上放置时，所述微针原 片500的一部分用于伸出所述上料平台103的出料侧S以搭于所述第一托底料带1011上，所述出料侧S靠近模切工位A2。设置上料平台103后，可以更好的保证微针原片500与第一托底料带1011之间的贴合平整，确保贴合精度。优选，所述上料平台103能够吸附所述微针原片500，以防止微针原片500与第一托底料带1011贴合时翘起。优选，所述上料平台103自身能够移动和/或转动，通过上料平台103的移动和/或转动，将微针原片500的一部分推送出所述上料平台103的出料侧S。
在一实施方式中，所述上料平台103负压吸附(包括真空吸附或非真空吸附)微针原片500。在另一实施例中，所述上料平台103静电吸附微针原片500。
在一具体示范例中，如图9至图15所示，所述上料平台103设有多个吸附孔1031，且所述上料平台103的内部形成有与所述吸附孔1031连通的负压腔1034。当微针原片500于上料平台103上完成摆放后，上料平台103开启负压吸附，将微针原片500固定在上料平台103上。吸附孔1031的作用是，一方面将微针原片500固定在上料平台103上，防止机构振动造成微针原片500偏移，另一方面第一托底料带1011拖拽微针原片500时，持久保持微针原片500的平整。吸附孔1031可以是均匀分布或不均匀分布，且分布形式不限于图中所示的矩形阵列。
在一实施例中，如图12所示，多个所述吸附孔1031沿微针原片500的出料方向A由疏到密分布。或者，多个所述吸附孔1031沿微针原片500的出料方向A由密到疏分布。优选，多个所述吸附孔1031沿微针原片500的出料方向A由疏到密分布，能够在第一托底料带1011拖拽微针原片500时，更好地保证微针原片500的平整。
在另一些实施例中，多个所述吸附孔1031沿垂直于出料方向A由密到疏或由疏到密分布。
在其他实施例中，多个所述吸附孔1031的分布密度为中间疏、边缘密或中间密、边缘疏；即上料平台103的中间部分的吸附孔1031的分布密度小，边缘部分的吸附孔1031的分布密度大，或者中间部分的吸附孔1031的分布密度大，边缘部分的吸附孔1031的分布密度小。
除了改变吸附孔1031的分布密度外，还可以调整吸附孔1031的孔径分布。如图13所示，在一实施例中，多个所述吸附孔1031的孔径沿出料方向A由小到大分布。在其他实施例中，多个所述吸附孔1031的孔径沿出料方向A由大到小分布。优选，多个所述吸附孔1031沿微针原片500的出料方向A由小到大分布，能够在第一托底料带1011拖拽微针原片500时，更好地保证微针原片500的平整。在另一些实施例中，多个所述吸附孔1031的孔径为上料平台103的中间部分的吸附孔1031的孔径大，上料平台103的边缘部分的吸附孔1031的孔径小，或者中间部分的吸附孔1031的孔径小，边缘部分的吸附孔1031的孔径大。或者，多个所述吸附孔1031的孔径沿垂直于出料方向A由大到小或由小到大分布。
微针原片500被第一托底料带1011逐渐脱离上料平台103的过程中，为了确保微针原片500的平整，优选在上料平台103的内部形成相互独立设置的多个所述负压腔1034，至少部分所述吸附孔1031不共用同一个负压腔1034。这样设置时，既便于微针原片500的出料，也便于在出料过程中有效地保证微针原片500的平整。如图9和图10所示，多个所述负压腔1034沿出料方向A布置，从而在出料方向A布置多个吸附区域，这些吸附区域相互独立。又如多个所述负压腔1034沿垂直于出料方向A布置，以在垂直于出料方向A上形成多个相互独立的吸附区域。又如多个所述负压腔1034中的一些分布在所述上料平台103的中间部分，另一些分布在所述上料平台103的边缘部分，从而在上料平台103的中间部分和边缘部分形成相互独立的吸附区域。需理解，本发明中，上料平台103的中间部分不能狭义地理解为绝对的中间位置，而应理解为被边缘部分包绕的区域。
如图14所示，并结合图9和图10，在一实施方式中，所述上料平台103沿出料方向A形成多排吸附结构，每排所述吸附结构包括沿垂直于所述出料方向A依次设置的多个所述吸附孔1031，多排所述吸附结构形成多行多列矩阵，如n行m列矩阵；一部分相邻行中的所述吸附孔1031不共用同一个负压腔1034，和/或，一部分相邻列中的所述吸附孔1031不共用同一个负压腔1034。如n行m列矩阵中，1～n1行共用一个负压腔1034，n1小于n，或者，1～m1列共用一个负压腔1034，m1小于m。在一优选实施例中，如图所示，所述上料平台103沿出料方向A形成的多排吸附结构中，为每一排吸附结构设置一个单独的负压腔1034，所有吸附结构相互不共用同一个负压腔1034。使用时，可以沿出料方向A依次开启或关闭吸附孔1031。
以上所应理解的是，负压腔1034的作用是为吸附孔1031提供负压吸力，当微针原片 500置于上料平台103后，通过负压吸附微针原片500，可以防止机构振动造成微针原片偏移，另外，负压吸附能够在第一托底料带1011拖拽微针原片过程中，持久保持微针原片的平整性。应理解，首先所有吸附孔1031被微针原片500所覆盖以对微针原片500进行吸附，继而微针原片500在第一托底料带1011的拖拽下向下游运动的过程中，远离出料侧S的吸附孔1031会被逐渐暴露在微针原片的外部；此时，如果所有吸附孔共用同一个负压腔，或者所有负压腔相互连通，则一旦有些吸附孔被裸露，则整个负压腔的负压环境被打破，吸力会大幅下降，大大影响到微针原片下方正在工作的吸附孔的吸力；而沿出料方向A独立设置各个负压腔时，裸露的吸附孔不会影响到其他与它独立设置的吸附孔的吸力，使微针原片下方正在工作的吸附孔保持良好的吸力，使托底料带拖拽微针原片过程，持久保持微针原片的平整。
所述上料平台103的结构不限定，如可以为单纯具有吸附功能的真空料台。所述上料平台103还可以为具有吸附功能的仿形传送带103a，如图15所示。将微针原片500放在仿形传送带103a上，可实现微针原片500的更快速上料，上料效率更高。所述仿形传送带103a也可不具备吸附功能，而是单纯地装载并输送微针原片500。当所述上料平台103为仿形传送带103a时，所述仿形传送带103a沿输送方向依次设置多个隔板1032，相邻所述隔板1032之间为一个传送节段，每个所述传送节段用于放置一个微针原片500；如此一来，可实现微针原片500的连续快速上料。
参阅图16，所述第一加工线S1还可包括辅助贴合机构，用于将微针原片500与所述第一托底料带1011相接合(接合包括粘接或粘附)，所述第一加工线S1还设有辅助贴合工位A7，所述辅助贴合工位A7设于所述上料工位A1和所述模切工位A2之间；所述第一托底料带1011自所述仿形传送带103a下方输送，并由下而上穿过所述仿形传送带103a的出料侧S和所述辅助贴合机构之间；其中每个所述隔板1032突出所述仿形传送带103a的传送面的高度小于所述出料侧S与所述辅助贴合机构之间的间隙宽度b。在出料侧S和所述辅助贴合机构之间形成有间隙，在所述间隙区域，仿形传送带103a弯折向下运动，隔板1032有一瞬间，会由垂直方向变成水平方向，此时，为了避免隔板1032卡住，隔板1032凸出传送面的高度需要小于间隙宽度b。
然而，除了负压吸附，所述上料平台103还可静电吸附微针原片500，如将上料平台103设置为静电吸盘。静电吸盘的好处在于，微针原片运动过程中，不存在漏气的问题，静电吸附力的稳定性好。在其他情况下，还可将上料平台103设置为由多个并排设置的上料辊轴1033组成，如图17所示。微针原片500放在上料辊轴1033上，利用上料辊轴1033的转动，可实现微针原片500的上料运动。所述上料辊轴1033可以仅转动而不具有吸附功能，或者上料辊轴1033具有负压吸附的功能或具有静电吸附的功能。
需说明的是，所述上料平台103自身可运动或不运动。在一实施例中，所述上料平台103自身可运动，如通过仿形传送带103a或通过上料辊轴1033，或者上料平台103由外部的驱动装置来推动而能够移动。通过上料平台103自身的运动，可将微针原片500的一部分推送出上料平台103的出料侧S。
为了更精确地控制微针原片500的上料位置，优选在上料平台103上设置限位挡板108，所述限位挡板108用于阻止微针原片500朝出料方向A以外的方向移动，从而在微针原片500的周围进行挡位。所述限位挡板108的大小可调节或不可调节。优选地，所述限位挡板208的大小可调节，以适用不同形状不同大小的微针原片500的上料。
例如图18所示，所述限位挡板108包括两个侧挡板1081和一个推板1082；两个所述侧挡板1081设置在所述推板1082的两相对侧；所述推板1082与两个所述侧挡板1081可移动地连接；推板1082不仅可以沿箭头B方向推动微针原片500，而且可以改变限位挡板108的大小。
在一实施方式中，所述限位挡板108的部分结构(如推板1082)能够相对于所述上料平台103移动，以将微针原片500的一部分推送出上料平台103的所述出料侧。
在一实施方式中，所述限位挡板108的整个结构能够相对于所述上料平台103移动。如图19所示，所述限位挡板108为一体式弯形推板108a，所述弯形推板108a为整体或一体式结构，其包绕并用于推动微针原片500，以此整体推进限位挡板108。所述限位挡板108可由驱动装置驱动其移动。所述驱动装置包括但不限于为电机。
在实际使用中，所述上料平台103和限位挡板108中的至少一个能够移动。优选，由上料平台103将微针原片500推送至辅助贴合工位A7，可以避免因微针原片500太薄，且推板与上料平台103之间的间隙大，造成上料困难的问题，此时，限位挡板108可仅限位使用。
所述辅助贴合机构可通过多种结构来实现，本发明对此限定。参阅图16，在一实施例中，所述辅助贴合机构包括第一辅助压合机构109，所述第一辅助压合机构109包括设于第一托底料带1011两相对侧的压板1091和贴合板1092，压板1091设于第一托底料带1011的上方，贴合板1092设于第一托底料带1011的下方；所述压板1091能够靠近或远离所述贴合板1092，所述压板1091于靠近所述贴合板1092时能够压抵微针原片500的边缘，以使微针原片500的边缘贴合至第一托底料带1011的边缘的胶面。第一辅助压合机构109的设置，可实现微针原片边缘与第一托底料带1011的紧密贴合。
在一具体实施例中，所述压板1091通过连接杆与气缸连接，当微针原片500到达辅助贴合工位A7后，第一托底料带1011停止运动，优选地，控制***控制开启气缸，并通过连接杆作用于压板1091，压板1091向下运动，将微针原片500的边缘与第一托底料带1011压合。压合后，所述控制***控制气缸带动压板1091向上抬起，恢复初始状态。此后，第一托底料带1011继续运动，将微针原片500拖至下一个工位。然而不限于气缸，在其他实施例中，例如可采用直线电机、电磁液压机构、摆杆机构等驱动压板1091运动。第一辅助压合机构109不局限于设置为一个，还可以是设置为依次并排的多个。
所述压板1091接触微针原片500的边缘，并使微针原片500的边缘贴合第一托底料带1011，此过程中，压板1091最好不接触第一托底料带1011，以免受到第一托底料带1011粘接力的影响。所述压板1091的形状最好匹配微针原片500暴露(伸出)出上料平台103的形状。如图20至图22所示，剖面线填充区域为压板1091，压板1091的形状匹配于微针原片500伸出上料平台103所形成的暴露区域103b的形状。
所述贴合板1092于上料平台103的出料侧S，在辅助贴合工位A7支撑第一托底料带1011，并与上料平台103的出料侧S之间形成间隙，第一托底料带1011自下而上穿过上料平台103和贴合板1092之间，以进一步在贴合板1092的上方输送；在一实施例中，贴合板1092与出料侧之间的间隙宽度b大于隔板1032的高度。
继续参阅图16，在另一实施例中，所述辅助贴合机构包括第一吹气机构110，用于向微针原片500吹气，使微针原片500与所述第一托底料带1011贴合。如此设置后，可达到非接触式贴合微针原片500与第一托底料带1011的效果。第一吹气机构110与第一辅助压合机构109可以择一设置或者同时设置。第一吹气机构110采用无接触吹气，可以较好的保护微针结构，防止产品污染。为了保证贴合的均匀，减少气泡，第一吹气机构110吹出的气体需经过出气孔1101的处理，形成均匀气流束。如图23和图24所示，所述第一吹气机构110具有若干出气孔1101，出气孔1101的分布方式包括但不限于矩阵形式，出气孔1101的形状可以是各种。第一吹气机构110直接对着微针原片500进行吹气。在一优选实施例中，所述辅助贴合机构既包括第一辅助压合机构109，还包括第一吹气机构110，第一吹气机构110设置在第一辅助压合机构109的上游或下游。第一吹气机构110的数量可以是一个或并排设置的多个。
参阅图16，在一实施方式中，所述贴片产品加工***还包括与控制***通信连接的第一视觉检测***501，所述控制***用于根据所述第一视觉检测***501的视觉检测信息控制微针原片500的出料和上料。本文中，微针原片500的出料是指微针原片500脱离上料平台103；微针原片500的上料是指微针原片500放置于上料平台103。
在一具体实施例中，所述控制***于第一视觉检测***501检测到上料平台103处于接收微针原片500的上料状态时，所述控制***先控制上料平台103开启吸附功能，将微针原片500固定在上料平台103上，此时，微针原片500的部分伸出上料平台103的出料侧，然后，所述控制***控制第一辅助压合机构109开启，令压板1091向下运动，将微针原片500伸出上料平台103的部分贴合在第一托底料带1011上，之后，压板1091向上运动复位。随后，第一托底料带1011将微针原片500拖拽以脱离上料平台103，此过程中，所述控制***控制第一吹气机构110吹气，使微针原片500完全贴合在第一托底料带1011上。当第一视觉检测***501检测到上料平台103处于未接受微针原片500的卸料状态时，即微针原片500被第一托底料带1011完全拖离上料平台103，第一视觉检测***501通知控制***重新向上料平台103放置微针原片500。进一步地，微针原片500放置于上料平台103时，限位挡板108可以实现微针原片500的精确定位摆放。此处，需理解，利用上料平台103对微针原片500的吸附固定，并搭配第一视觉检测***501的控制，可实现微针原片500的精确连续上料，加工精度更高。
参阅图16，在一具体实施例中，所述辅助贴合工位A7包括辅助压合工位和辅助贴合工位，辅助压合工位设置在辅助贴合工位的上游，第一辅助压合机构109先于辅助压合工位，将微针原片500的边缘贴合在第一托底料带1011上，然后，第一托底料带1011运动， 将微针原片500拖拽至辅助贴合工位，第一吹气机构110于辅助贴合工位，将整个微针原片500完全贴合在第一托底料带1011上。如第一视觉检测***501检测到微针原片500到达辅助压合工位后，第一托底料带1011保持不动，然后控制***控制开启第一辅助压合机构109，完成微针原片边缘与第一托底料带1011的初步贴合，接着第一托底料带1011运动，将微针原片500拖拽至辅助贴合工位，当第一视觉检测***501检测到微针原片500到达辅助贴合工位后，第一托底料带1011停止运动，然后控制***控制开启第一吹气机构110，完成整个微针原片500与第一托底料带1011的完全贴合，此后第一托底料带1011继续运动，将微针原片500拖拽至下一个工位。
在一实施方式中，所述贴片产品加工***还可包括控制***，与各条加工线通信连接，以控制各条加工线的自动化运行。然而需理解，各条加工线可单独设置控制***，也可所有加工线共用一个控制***。所述控制***主要与加工线中的电气部件通信连接，从而控制这些加工线中的动作部件的自动化运行，实现微针贴片的自动化生产，提高加工效率。本实施例对控制***的种类没有特别的限制，可以是执行逻辑运算的硬件，例如，单片机、微处理器、可编程逻辑控制器(PLC，Programmable Logic Controller)或者现场可编程逻辑门阵列(FPGA，Field-Programmable Gate Array)，或者是在硬件基础上的实现上述功能的软件程序、功能模块、函数、目标库(Object Libraries)或动态链接库(Dynamic-Link Libraries)。或者，是以上两者的结合。本领域技术人在本申请公开的内容的基础上，应当知晓如何具体实现控制***与其他设备间的通信。此外，采用控制***为本实施例的优选方式。
所述第一视觉检测***501的种类不限定，如可选用AI视觉***或其他常用的视觉检测设备。
参阅图25，所述辅助贴合机构可包括第二辅助压合机构111，所述第二辅助压合机构111包括设于第一托底料带1011两相对侧的第一辅助贴合压辊1111和第一辅助贴合支撑辊1112；所述第一辅助贴合压辊1111能够靠近或远离所述第一辅助贴合支撑辊1112；所述第一辅助贴合压辊1111于靠近所述第一辅助贴合支撑辊1112时能够压抵微针原片500的边缘，使微针原片500的边缘与第一托底料带1011贴合。优选地，第一辅助贴合压辊1111的辊面设有可变形的保护结构，如由无尘泡棉或其他软质材料制成保护结构，可以保护微针，降低微针结构受到破坏的风险。第一辅助贴合压辊1111的辊面包覆一圈保护结构以实现全面的保护。所述第二辅助压合机构111可以单独设置，也可以与其他结构的辅助贴合机构组合使用。所述第二辅助压合机构111可以是一个或并排设置的多个。本实施例中，第二辅助压合机构111还可张紧、牵引和输送第一托底料带1011。
在一具体实施例中，参阅图25，由机械或人工将微针原片500放置于上料平台103后，第一视觉检测***501检测到上料平台103上微针原片500完成放置后，通知控制***，控制***控制驱动装置驱动限位挡板108，将微针原片500推送至第一辅助贴合压辊1111处，使第一辅助贴合压辊1111将微针原片边缘贴合至第一托底料带1011，当第一视觉检测***501检测到微针原片500已被第一托底料带1011完全脱离上料平台103后，通知控制***再一次向上料平台103上料微针原片500。
在一实施例中，所述第一加工线S1还包括第一清洁机构112，用于在所述上料工位A1的下游和所述模切工位A2的上游以非接触方式去除微针原片500上的异物(如灰尘或其他杂质)。第一清洁机构112可以去除因静电或其它原因附着在微针原片500上的异物，保证产品的清洁。如第一清洁机构112产生离子风进行除尘。第一清洁机构112的数量不限定，如一个或多个第一清洁机构112。
返回参阅图1和图2，在一实施方式中，所述第二加工线S2包括第二托底料带2011、第二压合机构203、第二模切机构204、第三压合机构205和第三收废机构206，所述第二托底料带2011用于从所述第二加工线S2的上游向下游方向运动；所述第二加工线S2从上游至下游依次设有第一压合工位B1、模切工位B2、第二压合工位B3和收废工位B4；所述第二压合机构203于所述第一压合工位B1设有第二压合支撑辊2032和第二压合压辊2031；所述第二压合支撑辊2032和所述第二压合压辊2031分别位于所述第二托底料带2011的两相对侧，如第二压合压辊2031在第二托底料带2011的上方，第二压合支撑辊2032在第二托底料带2011的下方，以压合所述第二托底料带2011与一级防粘纸2021，使所述第二托底料带2011与一级防粘纸2021相接合；所述第二模切机构204于所述第二加工线S2的所述模切工位B2设有第二模切支撑辊2041和第二切刀2042，所述第二模切支撑辊2041和所述第二切刀2042分别位于所述第二托底料带2011的两相对侧，如第二模切支撑辊2041设于第二托底料带2011的上方，第二切刀2042设于第二托底料带2011的下方， 所述第二切刀2042用于切割所述一级防粘纸2021以形成所述二级防粘纸602’；所述第三压合机构205于所述第二压合工位B3设有第三压合压辊2051，所述第三压合压辊2051设于所述第二托底料带2011的一侧(背离防粘纸的一侧)，以压合所述二级防粘纸602’和所述二级粘性胶贴601(由第三加工线S3加工形成)，使所述二级防粘纸602’和所述二级粘性胶贴601相接合；所述第三收废机构206于所述收废工位B4通过所述第二托底料带2011回收所述一级防粘纸2021被切割后形成对应于镂空的废料，并使所述第二托底料带2011于所述第二压合工位B3与所述二级防粘纸602’分离。
在一实施方式中，所述第三收废机构206于所述收废工位B4设有卷绕所述第二托底料带2011的第二收废卷筒。
在一实施方式中，所述第二加工线S2还包括设于最上游的第二托底料带材料卷201和一级防粘纸材料卷202，所述第二托底料带材料卷201设有成卷的第二托底料带2011，所述一级防粘纸材料卷202设有成卷的一级防粘纸2021，所述第二托底料带材料卷201和所述一级防粘纸材料卷202相互独立设置。所述第二托底料带2011和一级防粘纸2021经第二压合机构203作用实现紧密贴合，后经第二模切机构204模切，切出镂空，所述第三压合机构205用于实现二级粘性胶贴601与二级防粘纸602’的贴合，在贴合之前，需要由第三收废料机构206在收集第二托底料带2011的同时，收集一级防粘纸2021切割形成的镂空废料。所需理解，第二压合机构203和第三压合机构205还可以使第二托底料带2011处于紧绷状态，并且第二托底料带2011的设置，可以减小防粘纸的受力，减少其变形，最终保证防粘纸模切与贴合的位置精度。还需理解，在第二加工线S2中，第二托底料带材料卷201、第二压合机构203、第二模切机构204、第三压合机构205、第三收废料机构206还可对第二托底料带2011进行牵引输送。
继续参阅图1和图2，所述第三加工线S3包括第三托底料带3021、第四压合机构303、第三模切机构304、第四收废机构305和第五压合机构306，所述第三托底料带3021用于从所述第三加工线S3的上游向下游方向运动；所述第三加工线S3从上游至下游依次设有第一压合工位C1、模切工位C2和收废工位C3，所述第三加工线S3还设有第二压合工位C4，所述第三加工线S3的所述第二压合工位C1设于所述第三加工线S3的所述模切工位C2的下游，并与所述第三加工线S3的所述收废工位C3并行设置；所述第四压合机构303于所述第三加工线S3的所述第一压合工位C1设有第四压合支撑辊3032和第四压合压辊3031，所述第四压合支撑辊3032和所述第四压合压辊3031分别位于所述第三托底料带3021的两相对侧，如第四压合支撑辊3032设于第三托底料带3021的下方，第四压合压辊3031设于第三托底料带3021的上方，以压合所述第三托底料带3021与一级粘性胶带3011，以使所述第三托底料带3021与所述一级粘性胶带相接合；所述第三模切机构304于所述第三加工线S3的所述模切工位C2设有第三切刀3041和第三模切支撑辊3042，所述第三模切支撑辊3042和所述第三切刀3041分别位于所述第三托底料带3021的两相对侧，如第三模切支撑辊3042设于第三托底料带3021的下方，第三切刀3041设于第三托底料带3021的上方，所述第三切刀3041用于切割所述一级粘性胶带3011以形成所述二级粘性胶贴601；所述第四收废机构305于所述第三加工线S3的所述收废工位C3回收所述一级粘性胶带3011切割形成的废料；所述第五压合机构306于所述第三加工线S3的所述第二压合工位C4设有第五压合支撑辊3061，所述第五压合支撑辊3061设于所述第三托底料带3021的一侧(背离粘性胶带的一侧)，用于压合所述二级防粘纸602’和所述二级粘性胶贴601。
所述第三压合压辊2051和所述第五压合支撑辊3061的位置对应，所述第二托底料带2011和所述第三托底料带3021从所述第三压合压辊2051和所述第五压合支撑辊3061之间穿过，且所述第三托底料带3021自所述第三加工线S3的所述第二压合工位C4继续向所述第四加工线S4输送，即第四加工线S4继续使用第三加工线S3提供的第三托底料带3021。
所述第三加工线S3还包括设于最上游的一级粘性胶带材料卷301和第三托底料带材料卷302，所述第三托底料带材料卷302设有成卷的第三托底料带3021，所述一级粘性胶带材料卷301设有成卷的一级粘性胶带3011，所述第三托底料带材料卷302和所述一级粘性胶带材料卷301相互独立设置。一级粘性胶带3011和第三托底料带3021经第四压合机构303压合后相互紧密贴合，后经第三模切机构304模切，切出二级粘性胶贴601。
还需理解，在第三加工线S3中，第三托底料带材料卷302、第四压合机构303、第三模切机构304、第五压合机构306、第四收废料机构305还可对第三托底料带3021进行牵引输送。
继续参阅图1和图2，所述第四加工线S4包括第三托底料带3021，以及剥离支撑机构401、贴合机构402、第四模切机构403、第五收废机构404、第二剥离机构407和第六收废机构408，所述第四加工线S4的所述第三托底料带3021用于从所述第四加工线S4的上游向下游方向运动；所述第四加工线S4从上游至下游依次设有贴合工位D1、模切工位D2和第一收废工位D3；所述第四加工线S4还设有剥离工位D4、第二收废工位D5和包装工位D6；所述第四加工线S4的所述剥离工位D4设于所述第四加工线S4的所述模切工位D2的下游，并与所述第四加工线S4的所述第一收废工位D3并行设置；所述第四加工线S4的所述第二收废工位D5和所述包装工位D6均设于所述第四加工线S4的所述剥离工位D4的下游，且并行设置；所述剥离支撑机构401于所述贴合工位D1设有剥离支撑辊，位于所述第三托底料带3021的一侧(如下方)；所述贴合机构402于所述贴合工位D1向微针贴片603施加作用力，使微针贴片603与所述一级背胶料带完全贴合；所述第四模切机构403于所述第四加工线S4的所述模切工位D2设有第四切刀4031和第四模切支撑辊4032，所述第四模切支撑辊4032和所述第四切刀4031分别位于所述第三托底料带3021的两相对侧，如第四模切支撑辊4032设于第三托底料带3021的下方，第四切刀4031设于第三托底料带3021的上方，所述第四切刀4031用于切割所述二级防粘纸602’以形成多个目标产品600；所述第五收废机构404于所述第四加工线S4的所述第一收废工位D3回收所述二级防粘纸602’被切割后形成的废料；所述第二剥离机构407于所述第四加工线S4的所述剥离工位D4设有第二剥离刀，所述第二剥离刀设置在所述第三托底料带3021背离微针贴片603的一侧，并通过自身的两相邻边顶住所述第三托底料带3021，使所述第三托底料带3021在所述第二剥离刀处由水平延伸方向转变至斜向上的延伸方向，以剥离所述目标产品600和所述第三托底料带3021，即第三托底料带3021通过第二剥离刀形成延伸方向不同的两部分，第三托底料带3021的两部分之间的夹角α小于90°，优选α小于或等于30°；所述第六收废机构408于所述第四加工线S4的所述第二收废工位D5回收所述第三托底料带3021；所述包装工位D6靠近所述第四加工线S4的所述剥离工位D4，所述包装工位D4设有包装盒700，剥离后的目标产品600掉入所述包装盒700。应理解，目标产品600的无胶面暴露，剥离后可直接放置在包装盒700，省去人工取样、装盒的过程。
如图26所示，在一应用场景中，微针原片500切割形成多个微针贴片603，微针贴片603按照一定方式排布在第一托底料带1011上。如图27所示，在一应用场景中，第三托底料带3021上承载有二级防粘纸602’，二级防粘纸602’上贴合有与微针贴片603数量一致的二级粘性胶贴601。在所述第四加工线S4的所述贴合工位D1，需要将与第一托底料带1011剥离后的所有微针贴片603与二级防粘纸602’上的二级粘性胶贴601一一对应地贴合。在一实施例中，微针贴片603与二级粘性胶贴601贴合后如图26所示。应理解，图7和图28中，虚线即表示当前视角下，二级粘性胶贴601不可见而以虚线表示。
在一实施例中，如图2所示，所述贴合机构402包括第二吹气机构4021和贴合支撑平台4022，分别设置在第三托底料带3021的两侧(上方和下方)。通过第二吹气机构4021向第三托底料带3021方向形成的气流束，实现微针贴片603与二级粘性胶贴601的贴合。优选地，所述第二吹气机构4021能够靠近或远离所述贴合支撑平台4022，以便调整第二吹气机构4021的位置来调整合适的气流束。在一示例中，如图29所示，所述贴合机构402还包括驱动机构4023和限位杆4024；所述驱动机构4023与第二吹气机构4021连接，以驱动第二吹气机构4021靠近或远离贴合支撑平台4022；所述限位杆4024分别与第二吹气机构4021及贴合支撑平台4022连接；第二吹气机构4021用于沿限位杆4024的方向进行移动。所述限位杆4024的数量可以是一根或对称设置的多根，限位杆4024可以精确地限定第二吹气机构4021的水平位置，防止下降过程中位置发生偏差。所述驱动机构4023的结构不限定，如直线电机、气缸等。
所述第四加工线S4优选还包括第二视觉检测***502，第二视觉检测***502检测到第三托底料带膜3021到达指定位置(如贴合工位D1)，第三托底料带3021运动停止，驱动机构4023驱动第二吹气机构4021下降靠近贴合支撑平台4022。在一优选实施例中，如图30所示，所述第二吹气机构4021包括吹气平台4021a，所述吹气平台4021a设有多个出气孔4021b，所述出气孔4021b的数量与微针贴片603的数量一致，每个所述微针贴片603由对应的一个所述出气孔4021b对其吹气，使整个微针贴片603与二级粘性胶贴601贴合，即各个出气孔4021b正好对准微针贴片603。所述出气孔4021b的孔径大于或等于所述微针贴片603的直径，优选，出气孔4021b的孔径大于微针贴片603的直径，以使吹气平台4021a形成下沉式结构，不仅可以防止微针被压坏，而且还可以套设微针贴片，增 大了气流利用率，避免干扰气流的影响，吹气效果更好。
所有出气孔4021b可以共用一个气道或独立设置气道。如吹气平台4021a上可设置控制气道开启或关闭的电磁阀，当电磁阀打开时，吹气平台4021a，开始吹气，一段时间后(如2～15s)后停止吹气，吹气平台4021a上升，恢复原位，完成微针贴片603的贴合，此后，第三托底料带3021运动，到达下一个模切工位D2。第二视觉检测***502的设置，可以实现微针贴片603的精确贴合。所述第二视觉检测***502的种类不限定，如可选用AI视觉***或其他常用的视觉检测设备。
在另一实施例中，如图31所示，所述贴合机构402可包括与所述剥离支撑辊位置相对应的剥离贴合压辊409，所述剥离贴合压辊409和所述剥离支撑辊设于所述第三托底料带3021的两侧(上侧和下侧)，所述剥离贴合压辊用于压抵所述微针贴片603的边缘。优选地，所述剥离贴合压辊409的辊面设有保护材料，如无尘泡棉等。
在一优选实施例中，所述第四加工线S4还包括第二清洁机构410，设于所述贴合工位D1的下游，用于以非接触方式去除所述微针贴片603上的异物。第二清洁机构410可以去除因静电或其它原因附着在微针贴片603上的异物，保证产品的清洁。如第二清洁机构410产生离子风进行除尘。第二清洁机构410的数量不限定，如一个或多个。
返回参阅图2，在一实施方式中，二级防粘纸602’经过模切后，第三托底料带3021经若干转向辊进行180°转向后，再对目标产品600进行剥离，并可自动剥离到包装盒700中。本发明对转向辊的数量不限定，如本实施例中，转向辊的数量为两个，分别为第一转向辊405和第二转向辊406，第一转向辊405将第三托底料带3021从水平方向转向至竖直方向，第二转向辊406将第三托底料带3021从竖直方向转向至水平方向。
综上所述，根据本发明实施例提供的技术方案，本发明能够实现微针贴片产品的连续且大批量的自动化生产，提高微针贴片产品的加工效率和加工稳定性，降低加工成本。具体地，本发明能够实现微针原片、防粘纸、粘性胶带的并行模切，提高微针贴片产品的加工效率。此外，完成模切的二级粘性胶贴、二级防粘纸和微针贴片自行汇聚贴合，并剥离至相应包装盒中，自动完成后续封口包装，无需人工干预，在提高加工效率的同时，提升了产品加工的稳定性，确保了贴片式目标产品的质量。
虽然本发明披露如上，但并不局限于此。本领域的技术人员可以对本发明进行各种改动和变型而不脱离本发明的精神和范围。这样，倘若本发明的这些修改和变型属于本发明及其等同技术的范围之内，则本发明也意图包含这些改动和变型在内。

Claims (24)

  1. 一种贴片产品加工***，其特征在于，包括第一加工线、第二加工线、第三加工线和第四加工线；所述第一加工线、所述第二加工线和所述第三加工线并行运行；所述第四加工线相对于所述第一加工线、所述第二加工线和所述第三加工线串行运行；
    所述第一加工线用于将目标物原片加工形成具有预定结构的目标物贴片；
    所述第二加工线用于将一级防粘纸加工形成具有镂空的二级防粘纸；
    所述第三加工线用于将一级粘性胶带加工形成具有预定结构的二级粘性胶贴；
    所述第二加工线还用于将所述二级粘性胶贴与所述二级防粘纸相接合，得到一级背胶料带；
    所述第四加工线用于将所述目标物贴片与所述一级背胶料带相接合，所述目标物贴片置于所述镂空中，并且所述目标物贴片的一面与所述二级粘性胶贴粘接。
  2. 根据权利要求1所述的贴片产品加工***，其特征在于，所述第四加工线被配置为先将所述目标物贴片与所述一级背胶料带相接合得到中间产品，然后将所述中间产品切割形成多个具有预定结构的目标产品；
    所述目标产品由所述二级粘性胶贴、三级防粘纸以及所述目标物贴片组成；所述三级防粘纸由所述二级防粘纸切割形成，所述三级防粘纸的中部具有所述镂空，所述三级防粘纸的边沿延伸超出所述二级粘性胶贴的边沿，所述二级粘性胶贴沿所述镂空的边缘设置。
  3. 根据权利要求1所述的贴片产品加工***，其特征在于，所述第一加工线包括第一托底料带、第一模切机构、第一剥离机构、第一收废机构和第二收废机构，所述第一托底料带能够从所述第一加工线的上游向下游方向移动；
    所述第一加工线从上游至下游依次设有上料工位、模切工位、第一收废工位、剥离工位和第二收废工位；
    所述第一托底料带于所述上料工位与所述目标物原片接合；
    所述第一模切机构于所述模切工位设有第一模切支撑辊和第一切刀，所述第一模切支撑辊和所述第一切刀分别位于所述第一托底料带的两相对侧，所述第一切刀用于切割所述目标物原片以形成所述目标物贴片；
    所述第一收废机构于所述第一收废工位回收所述目标物原片被切割后形成的废料；
    所述第一剥离机构于所述剥离工位设有第一剥离刀，所述第一剥离刀设置在所述第一托底料带背离所述目标物贴片的一侧；所述第一剥离刀通过自身两相邻边顶住所述第一托底料带，使所述第一托底料带在所述第一剥离刀处由最初的水平延伸方向转变至斜向下的延伸方向，以剥离所述目标物贴片和所述第一托底料带；
    所述第二收废机构于所述第二收废工位回收所述第一托底料带。
  4. 根据权利要求3所述的贴片产品加工***，其特征在于，所述第一加工线具有以下特征中的至少一种：
    所述第一收废机构于所述第一收废工位设有第一收废支撑辊和第一收废压辊，所述第一收废支撑辊和所述第一收废压辊分别位于所述第一托底料带的两相对侧，所述第一收废机构还设有排废胶带、送料卷筒和排料卷筒，所述送料卷筒、所述第一收废压辊和所述排料卷筒依次通过所述排废胶带连接，所述排废胶带由所述送料卷筒送出，并经过所述第一收废压辊的压抵后粘接所述废料，粘接废料的所述排废胶带由所述排料卷筒回收；
    所述第二收废机构于所述第二收废工位设有卷绕所述第一托底料带的第一收废卷筒；
    所述第一加工线还包括能够张紧所述第一托底料带的第一压合机构，所述第一加工线还设有压合工位，所述压合工位设于所述上料工位的上游，所述第一压合机构于所述压合工位设有第一压合支撑辊和第一压合压辊，所述第一压合支撑辊和所述第一压合压辊分别位于所述第一托底料带的两相对侧；以及，
    所述第一加工线还包括设于最上游的第一托底料带材料卷，所述第一托底料带材料卷设有成卷的第一托底料带。
  5. 根据权利要求3所述的贴片产品加工***，其特征在于，所述第一加工线还包括辅助贴合机构，用于将所述目标物原片与所述第一托底料带相贴合，所述第一加工线还设有辅助贴合工位，所述辅助贴合工位设于所述上料工位和所述模切工位之间，所述第一托底料带自所述上料平台下方输送，并由下而上穿过所述上料平台的出料侧和所述辅助贴合机构之间。
  6. 根据权利要求5所述的贴片产品加工***，其特征在于，所述辅助贴合机构设置为以下特征中的至少一种：
    所述辅助贴合机构包括第一辅助压合机构，所述第一辅助压合机构包括设于所述第一托底料带两相对侧的压板和贴合板；所述压板能够靠近或远离所述贴合板，所述压板于靠近所述贴合板时能够压抵所述目标物原片的边缘，使所述目标物原片的边缘与所述第一托底料带贴合；
    所述辅助贴合机构包括第一吹气机构，用于向所述目标物原片吹气，使所述目标物原片与所述第一托底料带贴合；以及，
    所述辅助贴合机构包括第二辅助压合机构，所述第二辅助压合机构包括设于所述第一托底料带两相对侧的第一辅助贴合压辊和第一辅助贴合支撑辊，所述第一辅助贴合压辊能够靠近或远离所述第一辅助贴合支撑辊，所述第一辅助贴合压辊于靠近所述第一辅助贴合支撑辊时能够压抵所述目标物原片的边缘，使所述目标物原片的边缘与所述第一托底料带贴合，所述第一辅助贴合压辊的辊面包绕有保护材料。
  7. 根据权利要求1-6中任一项所述的贴片产品加工***，其特征在于，所述第一加工线包括用于放置所述目标物原片的上料平台；所述上料平台能够吸附所述目标物原片，和/或，所述上料平台自身能够移动和/或转动，以将所述目标物原片的一部分推送出所述上料平台。
  8. 根据权利要求7所述的贴片产品加工***，其特征在于，所述上料平台设有多个吸附孔，且所述上料平台的内部形成有与所述吸附孔连通的负压腔，其中所述上料平台具有以下特征中的至少一种：
    多个所述吸附孔沿所述目标物原片的出料方向由密到疏或由疏到密分布；
    多个所述吸附孔沿垂直于所述目标物原片的出料方向由密到疏或由疏到密分布；
    多个所述吸附孔的分布密度为中间疏、边缘密或中间密、边缘疏；
    多个所述吸附孔的孔径沿所述目标物原片的出料方向由大到小或由小到大分布；
    多个所述吸附孔的孔径沿垂直于所述目标物原片的出料方向由大到小或由小到大分布；
    多个所述吸附孔的孔径为中间部分的孔径大、边缘部分的孔径小或中间部分的孔径小、边缘部分的孔径大。
  9. 根据权利要求8所述的贴片产品加工***，其特征在于，所述上料平台沿所述目标物原片的出料方向形成多排吸附结构，每排所述吸附结构包括沿垂直于所述出料方向依次设置的多个所述吸附孔，多排所述吸附结构形成多行多列矩阵；一部分相邻行中的所述吸附孔不共用同一个负压腔，和/或，一部分相邻列中的所述吸附孔不共用同一个负压腔。
  10. 根据权利要求9所述的贴片产品加工***，其特征在于，所述上料平台设置有多个独立设置的所述负压腔，所述负压腔设置为以下特征中的一种：
    多个所述负压腔沿所述目标物原片的出料方向依次布置；
    多个所述负压腔沿垂直于所述目标物原片的出料方向依次布置；
    多个所述负压腔中的一些分布在所述上料平台的中间，另一些分布在所述上料平台的边缘。
  11. 根据权利要求7所述的贴片产品加工***，其特征在于，所述上料平台为仿形传送带，所述仿形传送带沿输送方向依次设置多个隔板，相邻所述隔板之间为一传送节段，每个所述传送节段用于放置一个所述目标物原片。
  12. 根据权利要求11所述的贴片产品加工***，其特征在于，所述第一加工线还包括辅助贴合机构，用于将所述目标物原片与第一托底料带相贴合，所述第一托底料带用于输送所述目标物原片；
    所述第一托底料带自所述仿形传送带下方输送，并由下而上穿过所述仿形传送带的出料侧和所述辅助贴合机构之间；其中每个所述隔板突出所述仿形传送带的传送面的高度小于所述上料平台的出料侧与所述辅助贴合机构之间的间隙宽度。
  13. 根据权利要求7-12中任一项所述的贴片产品加工***，其特征在于，所述上料平台上设有限位挡板，所述限位挡板用于阻止所述目标物原片朝出料方向以外的方向移动。
  14. 根据权利要求13所述的贴片产品加工***，其特征在于，所述限位挡板的大小可调节，和/或，所述限位挡板的至少部分结构能够相对于所述上料平台移动，以将所述目标物原片的一部分推送出所述上料平台。
  15. 根据权利要求14所述的贴片产品加工***，其特征在于，所述限位挡板包括两个侧挡板和一个推板，两个所述侧挡板设置在所述推板的两相对侧，所述推板与两个所述侧挡板可移动地连接，或者，所述限位挡板为一体式弯形推板，所述弯形推板包绕并用于推动所述目标物原片。
  16. 根据权利要求1所述的贴片产品加工***，其特征在于，所述第二加工线包括第二托底料带、第二压合机构、第二模切机构、第三压合机构和第三收废机构，所述第二托底料带用于从所述第二加工线的上游向下游方向运动；
    所述第二加工线从上游至下游依次设有第一压合工位、模切工位、第二压合工位和收废工位；
    所述第二压合机构于所述第一压合工位设有第二压合支撑辊和第二压合压辊，所述第二压合支撑辊和所述第二压合压辊分别位于所述第二托底料带的两相对侧，以使所述第二托底料带与所述一级防粘纸相接合；
    所述第二模切机构于所述模切工位设有第二模切支撑辊和第二切刀，所述第二模切支撑辊和所述第二切刀分别位于所述第二托底料带的两相对侧，所述第二切刀用于切割所述一级防粘纸以形成所述二级防粘纸；
    所述第三压合机构于所述第二压合工位设有第三压合压辊，所述第三压合压辊设于所述第二托底料带的一侧，以使所述二级防粘纸和所述二级粘性胶贴相接合；
    所述第三收废机构于所述收废工位通过所述第二托底料带回收所述一级防粘纸被切割后形成对应于所述镂空的废料，并使所述第二托底料带于所述第二压合工位与所述二级防粘纸分离。
  17. 根据权利要求16所述的贴片产品加工***，其特征在于，所述第二加工线具有以下特征中的至少一种：
    所述第三收废机构于所述收废工位设有卷绕所述第二托底料带的第二收废卷筒；以及，
    所述第二加工线还包括设于最上游的第二托底料带材料卷和一级防粘纸材料卷，所述第二托底料带材料卷设有成卷的第二托底料带，所述一级防粘纸材料卷设有成卷的一级防粘纸，所述第二托底料带材料卷和所述一级防粘纸材料卷相互独立设置。
  18. 根据权利要求17所述的贴片产品加工***，其特征在于，所述第二加工线包括第三压合机构，所述第三压合机构于所述第二压合工位设有第三压合辊，所述第三压合压辊设于所述第二托底料带的一侧；
    所述第三加工线具有第三托底料带和第五压合支撑辊，所述第五压合支撑辊设于所述第二托底料带的另一侧；
    所述第三压合压辊和所述第五压合支撑辊的位置相对应；所述第二托底料带和所述第三托底料带从所述第三压合压辊和所述第五压合支撑辊之间穿过，且所述第四加工线和所述第三加工线共用所述第三托底料带。
  19. 根据权利要求1所述的贴片产品加工***，其特征在于，所述第四加工线包括第三托底料带、剥离支撑机构、贴合机构、第四模切机构、第五收废机构、第二剥离机构和第六收废机构，所述第三托底料带用于从所述第四加工线的上游向下游方向运动；
    所述第四加工线从上游至下游依次设有贴合工位、模切工位和第一收废工位；所述第四加工线还设有剥离工位、第二收废工位和包装工位；所述剥离工位设于所述模切工位的下游，并与所述第一收废工位并行设置；所述第二收废工位和所述包装工位均设于所述剥离工位的下游且并行设置；
    所述剥离支撑机构于所述贴合工位以及所述第三托底料带的一侧设有剥离支撑辊；
    所述贴合机构于所述贴合工位向所述目标物贴片施加作用力，以使所述目标物贴片与所述一级背胶料带接合；
    所述第四模切机构于所述模切工位设有第四模切支撑辊和第四切刀，所述第四模切支撑辊和所述第四切刀分别位于所述第三托底料带的两相对侧，所述第四切刀用于切割所述二级防粘纸以形成多个所述目标产品；
    所述第五收废机构于所述第一收废工位回收所述二级防粘纸被切割后形成的废料；
    所述第二剥离机构于所述剥离工位设有第二剥离刀，所述第二剥离刀设置在所述第三托底料带背离所述目标产品的一侧；所述第二剥离刀通过自身两相邻边顶住所述第三托底料带，使所述第三托底料带在所述第二剥离刀处由最初的水平延伸方向转变至斜向上的延伸方向，以剥离所述目标产品和所述第三托底料带；
    所述第六收废机构于所述第二收废工位回收所述第三托底料带；
    所述包装工位靠近所述剥离工位设置，所述包装工位设有包装盒，剥离后的所述目标产品自动掉入所述包装盒。
  20. 根据权利要求19所述的贴片产品加工***，其特征在于，所述贴合机构包括与所述剥离支撑辊位置相对应的剥离贴合压辊，所述剥离贴合压辊和所述剥离支撑辊设于所述 第三托底料带的两相对侧，所述剥离贴合压辊用于压抵所述目标物贴片的边缘，使所述目标物贴片与所述二级粘性胶贴接合，所述剥离贴合压辊的辊面包绕有可变形的保护结构。
  21. 根据权利要求20所述的贴片产品加工***，其特征在于，所述贴合机构包括第二吹气机构和贴合支撑平台，所述第二吹气机构和所述贴合支撑平台分别设置在所述第三托底料带的两相对侧；所述第二吹气机构能够靠近或远离所述贴合支撑平台；所述第二吹气机构于靠近所述贴合支撑平台时用于向所述目标物贴片吹气，使所述目标物贴片与所述二级粘性胶贴接合。
  22. 根据权利要求21所述的贴片产品加工***，其特征在于，所述目标物贴片的数量为多个，所述第二吹气机构包括吹气平台，所述吹气平台设有多个出气孔，所述出气孔的数量和位置与所述目标物贴片的数量及位置相对应，每个所述目标物贴片由对应的一个所述出气孔对其吹气，所述出气孔的孔径大于所述目标物贴片的直径，所述吹气平台于靠近所述贴合支撑平台时，所述出气孔套设所述目标物贴片进行吹气。
  23. 根据权利要求19-22中任一项所述的贴片产品加工***，其特征在于，所述第四加工线还包括与控制***通信连接的第二视觉检测***，所述控制***用于根据所述第二视觉检测***的视觉检测信息控制所述贴合机构的状态。
  24. 一种贴片产品加工方法，其特征在于，所述加工方法由权利要求1-23中任一项所述的贴片产品加工***所实施。
PCT/CN2023/095936 2022-06-22 2023-05-24 贴片产品加工***及贴片产品加工方法 WO2023246407A1 (zh)

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