WO2023097760A1 - Animal ethology experiment box - Google Patents

Animal ethology experiment box Download PDF

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Publication number
WO2023097760A1
WO2023097760A1 PCT/CN2021/137519 CN2021137519W WO2023097760A1 WO 2023097760 A1 WO2023097760 A1 WO 2023097760A1 CN 2021137519 W CN2021137519 W CN 2021137519W WO 2023097760 A1 WO2023097760 A1 WO 2023097760A1
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Prior art keywords
experiment box
plates
rod
animal behavior
opening
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PCT/CN2021/137519
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French (fr)
Chinese (zh)
Inventor
徐阳
黄康
***
王枫
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中国科学院深圳先进技术研究院
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Publication of WO2023097760A1 publication Critical patent/WO2023097760A1/en

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00—Housing animals; Equipment therefor
    • A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03—Housing for domestic or laboratory animals
    • A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00—Housing animals; Equipment therefor
    • A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/035—Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research

Definitions

  • the present application relates to the technical field of animal experiment equipment, for example, to an animal behavior experiment box.
  • Experimental animal ethology is a branch of biology, which provides experimental evidence for exploring the neurobiological mechanism behind the behavior by recording and analyzing the behavior of experimental animals in a specific environment. It is widely used in research fields such as life science, medicine, pharmacy and military science, especially in neuroscience. Behavior is affected by both the internal state of the organism and the environment. The internal state of the organism (such as gene expression, multiple physiological indicators, etc.) and changes in the external environment (such as changes in the strength of smell, sound, light, etc.) type and behavioral patterns. Therefore, a reliable and applicable ethological device is of great significance for neuroscience research.
  • the open field experimental device is mainly composed of an open field test box and a data acquisition system.
  • the behavioral activities of mice are studied by analyzing the movement distance or time of animals in different parts of the open field, such as the overall, central, and peripheral areas; the new object/position recognition experiment is based on Rodents are designed to have a natural novelty preference.
  • the spatial reference memory ability of the animal is tested; the visual instinctive fear behavior is based on Rodents are designed to have a defensive response to the approaching shadow stimulus from the upper field of view.
  • the animal will have different defensive responses depending on whether there is a "shelter”, and will produce a freezing-like reaction when there is nowhere to escape. behavior, and when there is a nest, it will give priority to escape.
  • the animal's visual instinctive fear response level is evaluated.
  • This application provides an animal behavior experiment box, the size of which can be adjusted, which can meet the needs of different behavior paradigms, improves universality and convenience, and can also block light and sound insulation, reducing the external environment during the experiment. The effect of changes on the experimental results.
  • An animal behavior experiment box comprising:
  • the frame is spliced by a plurality of rods, and the length of the rods can be adjusted, and the frame has a top opening, a bottom opening and a plurality of side openings;
  • a plurality of sealing plates are respectively sealed at the top opening, the bottom opening and the plurality of side openings, and the size of the sealing plates can be adjusted according to the length of the rod.
  • the panels are set to blackout and soundproof.
  • Fig. 1 is a schematic structural view of a telescopic light-shielding and sound-proof animal behavior experiment box provided by the embodiment of the present application;
  • Fig. 2 is a schematic structural view of a retractable light-shielding and sound-insulating animal behavior experiment box provided by the embodiment of the present application after the second sealing plate is removed.
  • connection should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral body; It can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediary, it can be the internal communication of two components or the interaction relationship between two components.
  • connection can be a fixed connection, a detachable connection, or an integral body; It can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediary, it can be the internal communication of two components or the interaction relationship between two components.
  • a first feature being "on” or “under” a second feature may include that the first and second features are in direct contact, and may also include that the first and second features are not in direct contact. contact but through additional feature contact between them.
  • “above”, “above” and “above” the first feature on the second feature include that the first feature is directly above and obliquely above the second feature, or simply means that the first feature is horizontally higher than the second feature.
  • "Below”, “beneath” and “under” the first feature to the second feature include that the first feature is directly below and obliquely below the second feature, or simply means that the first feature has a lower level than the second feature.
  • the terms “upper”, “lower”, “left”, “right”, etc. are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of description and simplification of operation. , rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and thus should not be construed as limiting the application.
  • the terms “first” and “second” are only used to distinguish in description, and have no special meaning.
  • the embodiment of the present application provides a telescopic light-shielding and sound-proof animal behavior experiment box to provide a closed experimental environment for the behavior box of animal behavior experiments.
  • a telescopic light-shielding and sound-proof animal behavior experiment box to provide a closed experimental environment for the behavior box of animal behavior experiments.
  • the telescopic light-shielding and soundproof animal behavior experiment box provided by the embodiment of the present application, as shown in Figure 1 and Figure 2, includes a frame 10 and a plurality of sealing plates, the frame 10 is spliced by a plurality of rods 11, and the rods
  • the length of the part 11 can be adjusted, and the frame 10 has a top opening, a bottom opening and a plurality of side openings; a plurality of sealing plates are respectively sealed at the top opening, the bottom opening and a plurality of side openings, and the size of the sealing plates can be adjusted according to the
  • the length of the rod 11 is adjusted and adjusted, and the sealing plate can be light-shielding and sound-proof.
  • the telescopic light-shielding and sound-proof animal behavior experiment box provided by the embodiment of the present application can adjust the length of the rod 11 by setting the length of the rod 11, and the size of the sealing plate can be adjusted according to the length of the rod 11, so that the The size of the telescopic light-shielding and sound-proof animal behavior experiment box can be adjusted, so as to meet the needs of different behavioral paradigms, and improve the universality and convenience of the telescopic light-shielding and sound-proof animal behavior experiment box;
  • the boards are all set to be able to shading and sound insulation, which reduces the impact of external environment changes on the experimental results during the experiment.
  • the rods 11 that are spliced into the frame 10 include a first rod 111 and a second rod 112, one of the first rod 111 and the second rod 112 is provided with a sliding cavity, and one end of the other is slidably connected to a sliding cavity.
  • the sealing plate includes a first sealing plate 20 and a second sealing plate 30 , the first sealing plate 20 covers the top opening and the bottom opening, and the second sealing plate 30 covers the side opening.
  • the first cover plate 20 includes four triangular sub-plates 21, and the four triangular sub-plates 21 are respectively arranged at the four corners of the top opening or the bottom opening, and each adjacent two triangular sub-plates 21 can be opposite to each other. Sliding, the two side surfaces of the triangular sub-board 21 are respectively connected with the two rods 11 at the corner positions of the top opening or the bottom opening, and the bottom surfaces of the four triangular sub-boards 21 together form a hollow opening in the middle.
  • the four triangular sub-plates 21 in the first sealing plate 20 will slide relative to each other to adapt to the change in length of the rod 11 .
  • the triangular sub-plate 21 slides away from the center of the opening, and the area of the hollow opening in the middle becomes larger; when the length of the rod 11 becomes shorter, the triangular sub-plate 21 moves closer to the center of the opening. Sliding in the direction of , at this time, the area of the hollow opening in the middle becomes smaller.
  • the second cover plate 30 includes two square sub-boards 31 distributed left and right, and the two square sub-boards 31 can slide relative to each other.
  • the two square sub-boards 31 in the second sealing plate 30 will slide relative to each other to adapt to the change in length of the rod 11 .
  • the two square sub-plates 31 will slide relative to each other away from each other; when the length of the rod 11 enclosed into the top opening and the bottom opening becomes shorter , the two square sub-boards 31 slide relative to each other.
  • one of the square sub-boards 31 is provided with a chute, and the other square sub-board 31 is slidably arranged in the chute.
  • both the first sealing plate 20 and the second sealing plate 30 include a light-shielding plate and a sound-insulating layer, and the sound-insulating layer is disposed inside the light-shielding plate.
  • the structure is simple, and the effect of shading and sound insulation is better.
  • the shading plate is a black stainless steel plate, the material is conventional, and the cost is low.
  • the sound insulation layer is polyester fiber sound insulation cotton, which has good sound insulation effect and low cost.
  • the retractable light-shielding and sound-insulating animal behavior experiment box further includes a display screen (not shown in the figure), and the display screen is arranged in the frame 10 .
  • the display screen can not only illuminate the box, but also display various patterns to test the reaction of the animals in the box.
  • the telescopic light-shielding and sound-proof animal behavior experiment box also includes universal wheels (not shown in the figure), and a plurality of universal wheels are arranged at the bottom of the frame 10 .
  • universal wheels By setting universal wheels, it is convenient to move the experimental box to a suitable experimental position.
  • the length of the rods 11 spliced into the frame 10 is adjusted, and the four triangular sub-plates 21 of the first cover 20 and the two square sub-plates 31 of the second cover 30 are adjusted with the length of the rods 11.
  • the behavior box is generally cylindrical, and the bottom surface of the behavior box is generally divided into a square area in the middle and four fan-shaped areas around the square area.
  • the dwell time, total distance and average speed of the experimental animals in the central direction area and the surrounding fan-shaped area were used to analyze the spontaneous activities and anxiety behaviors of the experimental animals.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Husbandry (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Public Health (AREA)
  • Clinical Laboratory Science (AREA)
  • Housing For Livestock And Birds (AREA)

Abstract

An animal ethology experiment box, comprising a frame (10) and a plurality of sealing plates. The frame (10) is formed by combining together a plurality of rod members (11), and the lengths of the rod members (11) are adjustable. The frame (10) is provided with a top opening, a bottom opening, and a plurality of side openings. The plurality of sealing plates seals and covers the top opening, the bottom opening, and the plurality of side openings, respectively, and the sizes of the sealing plates can be adjusted in accordance with length adjustments of the rod members (11). The sealing plates are configured to have light-shielding and sound-insulation functions.

Description

动物行为学实验箱体Animal behavior experiment box
本申请要求在2021年12月02日提交中国专利局、申请号为202111457327.8的中国专利申请的优先权，该申请的全部内容通过引用结合在本申请中。This application claims the priority of a Chinese patent application with application number 202111457327.8 filed with the China Patent Office on December 02, 2021, the entire contents of which are incorporated herein by reference.
技术领域technical field
本申请涉及动物实验装置技术领域，例如涉及一种动物行为学实验箱体。The present application relates to the technical field of animal experiment equipment, for example, to an animal behavior experiment box.
背景技术Background technique
实验动物行为学是生物学中的一个分支学科，通过记录和分析实验动物在特定环境中表现出的行为，为探索其行为背后的神经生物学机制提供实验证据。被广泛应用于生命科学、医学、药学以及军事科学等研究领域中，尤其在神经科学中扮演着不可或缺的角色。行为受机体内在状态与环境的双重影响，机体内在状态(如基因表达、多项生理指标等)以及外界环境的变化(如气味、声音、光线等的强弱变化)都会对动物的行为类型及行为模式造成影响。因此，可靠且适用的动物行为学装置对于神经科学研究具有重要意义。Experimental animal ethology is a branch of biology, which provides experimental evidence for exploring the neurobiological mechanism behind the behavior by recording and analyzing the behavior of experimental animals in a specific environment. It is widely used in research fields such as life science, medicine, pharmacy and military science, especially in neuroscience. Behavior is affected by both the internal state of the organism and the environment. The internal state of the organism (such as gene expression, multiple physiological indicators, etc.) and changes in the external environment (such as changes in the strength of smell, sound, light, etc.) type and behavioral patterns. Therefore, a reliable and applicable ethological device is of great significance for neuroscience research.
为了评估实验动物的自发活动水平、情绪状态、认知水平等，旷场、新物体/位置识别以及视觉线索诱发的本能防御行为等实验范式被广泛应用。其中，旷场实验多用于观察动物自发活动与探索行为。旷场实验装置主要由旷场实验箱和数据采集***组成，通过分析动物于旷场总体、中央、周边等不同部位的运动距离或时间以研究小鼠的行为活动；新物体/位置识别实验基于啮齿类动物天生具有新奇偏爱的特性而设计，通过在旷场中设置新旧物体或新旧位置，检测动物对物体/位置的探索时间等参数，来检测动物的空间参考记忆能力；视觉本能恐惧行为根据啮齿类动物会对来自上视野不断迫近的阴影刺激产生防御反应这一特性来设计，动物会根据有无“避难所”产生不同的防御反应，在无处可逃的情况下会产生冻结样的行为，而有窝时则会优先选择逃跑，通过检测逃避潜伏期、逃跑速度、逃跑距离等参数，来评价动物视觉本能恐惧反应水平。In order to assess the spontaneous activity level, emotional state, cognitive level, etc. of experimental animals, experimental paradigms such as open field, novel object/location recognition, and instinctive defensive behavior induced by visual cues are widely used. Among them, the open field experiment is mostly used to observe the spontaneous activities and exploration behavior of animals. The open field experimental device is mainly composed of an open field test box and a data acquisition system. The behavioral activities of mice are studied by analyzing the movement distance or time of animals in different parts of the open field, such as the overall, central, and peripheral areas; the new object/position recognition experiment is based on Rodents are designed to have a natural novelty preference. By setting new and old objects or new and old positions in the open field, and detecting parameters such as the animal’s exploration time for the object/position, the spatial reference memory ability of the animal is tested; the visual instinctive fear behavior is based on Rodents are designed to have a defensive response to the approaching shadow stimulus from the upper field of view. The animal will have different defensive responses depending on whether there is a "shelter", and will produce a freezing-like reaction when there is nowhere to escape. behavior, and when there is a nest, it will give priority to escape. By detecting parameters such as escape latency, escape speed, and escape distance, the animal's visual instinctive fear response level is evaluated.
首先，在对上述提及的几种啮齿类动物行为学实验过程中发现，外界环境的变化(声、光等刺激)对动物产生的行为表现会有一定的影响，这几种实验操作流程和操作空间各不相同，但是所需要规避的环境影响因素几乎完全一致。然而，实验范式中并没有规避这些影响因素，对实验结果产生一定的影响。其次，从实验流程上分析，开展啮齿类动物行为学实验要求实验者提前将动物放置在实验环境中适应该环境，但是当开展不同的行为学实验时就要求动物需要适应不同的实验操作环境，这个动物适应环境的过程对实验者来说耗时耗力。 最后，为了避免环境因素对实验的影响，有些研究者也考虑使用黑色幕布或者遮光板等材料规避外界环境光刺激的影响，但是这种方法普适性及稳定性差并且不能实现隔音的效果。First of all, in the process of several rodent behavior experiments mentioned above, it was found that changes in the external environment (stimuli such as sound and light) would have a certain impact on the behavior of the animals. The operating spaces are different, but the environmental factors that need to be avoided are almost identical. However, these influencing factors were not avoided in the experimental paradigm, which had a certain impact on the experimental results. Secondly, from the analysis of the experimental process, the conduct of rodent behavioral experiments requires the experimenter to place the animals in the experimental environment in advance to adapt to the environment, but when carrying out different behavioral experiments, the animals are required to adapt to different experimental operating environments. This process of animal adaptation to the environment is time-consuming and labor-intensive for the experimenter. Finally, in order to avoid the influence of environmental factors on the experiment, some researchers also consider using materials such as black curtains or shading panels to avoid the influence of external environmental light stimuli, but this method has poor universality and stability and cannot achieve sound insulation effects.
因此，亟需一种动物行为学实验箱体以解决上述技术问题。Therefore, there is an urgent need for an animal behavior experiment box to solve the above-mentioned technical problems.
发明内容Contents of the invention
本申请提供一种动物行为学实验箱体，箱体尺寸能够调节，能够满足不同行为学范式的需求，提高了普适性和便捷性，另外还能够遮光和隔音，减少了实验过程中外界环境变化对实验结果的影响。This application provides an animal behavior experiment box, the size of which can be adjusted, which can meet the needs of different behavior paradigms, improves universality and convenience, and can also block light and sound insulation, reducing the external environment during the experiment. The effect of changes on the experimental results.
一种动物行为学实验箱体，包括：An animal behavior experiment box, comprising:
框架，由多个杆件拼接而成，且所述杆件的长度能够调节，所述框架具有顶部开口、底部开口以及多个侧部开口；The frame is spliced by a plurality of rods, and the length of the rods can be adjusted, and the frame has a top opening, a bottom opening and a plurality of side openings;
多个封板，分别封盖于所述顶部开口、所述底部开口以及所述多个侧部开口处，且所述封板的大小能够随所述杆件的长度调节而调节，所述封板设置为遮光和隔音。A plurality of sealing plates are respectively sealed at the top opening, the bottom opening and the plurality of side openings, and the size of the sealing plates can be adjusted according to the length of the rod. The panels are set to blackout and soundproof.
附图说明Description of drawings
图1是本申请实施例提供的一种伸缩式遮光隔音的动物行为学实验箱体的结构示意图；Fig. 1 is a schematic structural view of a telescopic light-shielding and sound-proof animal behavior experiment box provided by the embodiment of the present application;
图2是本申请实施例提供的一种伸缩式遮光隔音的动物行为学实验箱体去除第二封板之后的结构示意图。Fig. 2 is a schematic structural view of a retractable light-shielding and sound-insulating animal behavior experiment box provided by the embodiment of the present application after the second sealing plate is removed.
图中：In the picture:
10、框架；11、杆件；111、第一杆件；112、第二杆件；10. frame; 11. rod; 111. first rod; 112. second rod;
20、第一封板；21、三角形子板；20. The first sealing board; 21. The triangular sub-board;
30、第二封板；31、方形子板。30. The second sealing board; 31. The square sub-board.
具体实施方式Detailed ways
下面结合附图和实施方式说明本申请的技术方案。此处所描述的具体实施例仅仅用于解释本申请。为了便于描述，附图中仅示出了与本申请相关的部分。The technical solutions of the present application will be described below in conjunction with the accompanying drawings and embodiments. The specific embodiments described herein are for illustration of the application only. For ease of description, only parts relevant to the present application are shown in the drawings.
在本申请的描述中，除非另有规定和限定，术语“相连”、“连接”、“固定”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或成一体；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间 接相连，可以是两个元件内部的连通或两个元件的相互作用关系。对于本领域的普通技术人员而言，可以根据情况理解上述术语在本申请中的含义。In the description of this application, unless otherwise stipulated and limited, the terms "connected", "connected" and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral body; It can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediary, it can be the internal communication of two components or the interaction relationship between two components. Those of ordinary skill in the art can understand the meanings of the above terms in this application according to the situation.
在本申请中，除非另有规定和限定，第一特征在第二特征之“上”或之“下”可以包括第一和第二特征直接接触，也可以包括第一和第二特征不是直接接触而是通过它们之间的另外的特征接触。而且，第一特征在第二特征“之上”、“上方”和“上面”包括第一特征在第二特征正上方和斜上方，或仅仅表示第一特征水平高度高于第二特征。第一特征在第二特征“之下”、“下方”和“下面”包括第一特征在第二特征正下方和斜下方，或仅仅表示第一特征水平高度小于第二特征。In this application, unless otherwise specified and limited, a first feature being "on" or "under" a second feature may include that the first and second features are in direct contact, and may also include that the first and second features are not in direct contact. contact but through additional feature contact between them. Moreover, "above", "above" and "above" the first feature on the second feature include that the first feature is directly above and obliquely above the second feature, or simply means that the first feature is horizontally higher than the second feature. "Below", "beneath" and "under" the first feature to the second feature include that the first feature is directly below and obliquely below the second feature, or simply means that the first feature has a lower level than the second feature.
在本实施例的描述中，术语“上”、“下”、“左”、“右”、等方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述和简化操作，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本申请的限制。此外，术语“第一”、“第二”仅仅用于在描述上加以区分，并没有特殊的含义。In the description of this embodiment, the terms "upper", "lower", "left", "right", etc. are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of description and simplification of operation. , rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and thus should not be construed as limiting the application. In addition, the terms "first" and "second" are only used to distinguish in description, and have no special meaning.
本申请实施例提供一种伸缩式遮光隔音的动物行为学实验箱体，以为动物行为实验的行为箱提供封闭的实验环境，在对动物行为进行实验时，将装有实验动物的行为箱放入该动物行为学实验箱体中，以避免外界环境对实验造成影响。The embodiment of the present application provides a telescopic light-shielding and sound-proof animal behavior experiment box to provide a closed experimental environment for the behavior box of animal behavior experiments. When conducting experiments on animal behavior, put the behavior box containing experimental animals into The animal behavior experiment box is used to avoid the influence of the external environment on the experiment.
本申请实施例提供的伸缩式遮光隔音的动物行为学实验箱体，如图1和图2所示，包括框架10和多个封板，框架10由多个杆件11拼接而成，且杆件11的长度能够调节，框架10具有顶部开口、底部开口以及多个侧部开口；多个封板分别封盖于顶部开口、底部开口以及多个侧部开口处，且封板的大小能够随杆件11的长度调节而调节，封板能够遮光和隔音。The telescopic light-shielding and soundproof animal behavior experiment box provided by the embodiment of the present application, as shown in Figure 1 and Figure 2, includes a frame 10 and a plurality of sealing plates, the frame 10 is spliced by a plurality of rods 11, and the rods The length of the part 11 can be adjusted, and the frame 10 has a top opening, a bottom opening and a plurality of side openings; a plurality of sealing plates are respectively sealed at the top opening, the bottom opening and a plurality of side openings, and the size of the sealing plates can be adjusted according to the The length of the rod 11 is adjusted and adjusted, and the sealing plate can be light-shielding and sound-proof.
本申请实施例提供的伸缩式遮光隔音的动物行为学实验箱体，通过将杆件11设置为长度可调节，以及通过将封板设置为大小可随杆件11的长度调节而调节，使得该伸缩式遮光隔音的动物行为学实验箱体的尺寸能够调节，从而能够满足不同行为学范式的需求，提高了该伸缩式遮光隔音的动物行为学实验箱体的普适性和便捷性；另外封板全部设置为能够遮光和隔音，减少了实验过程中外界环境变化对实验结果的影响。The telescopic light-shielding and sound-proof animal behavior experiment box provided by the embodiment of the present application can adjust the length of the rod 11 by setting the length of the rod 11, and the size of the sealing plate can be adjusted according to the length of the rod 11, so that the The size of the telescopic light-shielding and sound-proof animal behavior experiment box can be adjusted, so as to meet the needs of different behavioral paradigms, and improve the universality and convenience of the telescopic light-shielding and sound-proof animal behavior experiment box; The boards are all set to be able to shading and sound insulation, which reduces the impact of external environment changes on the experimental results during the experiment.
拼接成框架10所用的杆件11包括第一杆件111和第二杆件112，第一杆件111和第二杆件112中的一个上设置有滑动腔，另一个的一端滑动连接于滑动腔中。通过上述设置，能够实现第一杆件111和第二杆件112的相对滑动伸缩，从而实现了杆件11的长度调节。The rods 11 that are spliced into the frame 10 include a first rod 111 and a second rod 112, one of the first rod 111 and the second rod 112 is provided with a sliding cavity, and one end of the other is slidably connected to a sliding cavity. Through the above arrangement, the relative sliding and telescoping of the first rod 111 and the second rod 112 can be realized, thereby realizing the adjustment of the length of the rod 11 .
封板包括第一封板20和第二封板30，第一封板20封盖于顶部开口和底部开口，第二封板30封盖于侧部开口。其中，第一封板20包括四块三角形子板21，四块三角形子板21分别设置于顶部开口或底部开口的四个角的位置，且每相邻两块三角形子板21之间能够相对滑动，三角形子板21的两侧面分别与形成顶部开口或底部开口的角位置的两个杆件11连接，四块三角形子板21的底面共同围合形成中部镂空口。当围合成顶部开口或底部开口的杆件11的长度发生变化时，第一封板20中的四块三角形子板21会发生相对滑动以适应杆件11长度的变化。当杆件11的长度变长时，三角形子板21朝远离开口中心的方向滑动，此时中部镂空口的面积变大；当杆件11的长度变短时，三角形子板21朝靠近开口中心的方向滑动，此时中部镂空口的面积变小。通过上述设置，既便于杆件11长度的调节，又便于通过中部镂空口将行为箱放置其内。动物实验的环境需要全封闭，在实际进行实验过程中，要配合两块盖板以对顶部和底部的中部镂空口进行封闭，操作会在下文详述。The sealing plate includes a first sealing plate 20 and a second sealing plate 30 , the first sealing plate 20 covers the top opening and the bottom opening, and the second sealing plate 30 covers the side opening. Wherein, the first cover plate 20 includes four triangular sub-plates 21, and the four triangular sub-plates 21 are respectively arranged at the four corners of the top opening or the bottom opening, and each adjacent two triangular sub-plates 21 can be opposite to each other. Sliding, the two side surfaces of the triangular sub-board 21 are respectively connected with the two rods 11 at the corner positions of the top opening or the bottom opening, and the bottom surfaces of the four triangular sub-boards 21 together form a hollow opening in the middle. When the length of the rod 11 surrounding the top opening or the bottom opening changes, the four triangular sub-plates 21 in the first sealing plate 20 will slide relative to each other to adapt to the change in length of the rod 11 . When the length of the rod 11 becomes longer, the triangular sub-plate 21 slides away from the center of the opening, and the area of the hollow opening in the middle becomes larger; when the length of the rod 11 becomes shorter, the triangular sub-plate 21 moves closer to the center of the opening. Sliding in the direction of , at this time, the area of the hollow opening in the middle becomes smaller. Through the above arrangement, it is convenient to adjust the length of the rod 11, and it is also convenient to place the behavior box in it through the hollow opening in the middle. The environment of the animal experiment needs to be fully enclosed. In the actual experiment process, two cover plates should be used to seal the hollow openings in the middle of the top and bottom. The operation will be described in detail below.
第二封板30包括两块方形子板31，两块方形子板31左右分布，且两块方形子板31能够相对滑动。当围合成顶部开口或底部开口的杆件11的长度发生变化时，第二封板30中的两块方形子板31会发生相对滑动以适应杆件11长度的变化。当围合成顶部开口以及底部开口的杆件11的长度变长时，两块方形子板31朝相互远离的方向发生相对滑动；当围合成顶部开口以及底部开口的杆件11的长度变短时，两块方形子板31朝相互靠近的方向发生相对滑动。通过上述设置，能够将侧部开口完全封闭，且方便调节。两块方形子板31中，其中一块方形子板31上开设有滑槽，另一块方形子板31滑动设置于滑槽中。通过上述设置，能够提高两块方形子板31调节的稳定性以及调节之后的密封性。The second cover plate 30 includes two square sub-boards 31 distributed left and right, and the two square sub-boards 31 can slide relative to each other. When the length of the rod 11 surrounding the top opening or the bottom opening changes, the two square sub-boards 31 in the second sealing plate 30 will slide relative to each other to adapt to the change in length of the rod 11 . When the length of the rod 11 enclosed into the top opening and the bottom opening becomes longer, the two square sub-plates 31 will slide relative to each other away from each other; when the length of the rod 11 enclosed into the top opening and the bottom opening becomes shorter , the two square sub-boards 31 slide relative to each other. Through the above arrangement, the side opening can be completely closed, and the adjustment is convenient. Among the two square sub-boards 31 , one of the square sub-boards 31 is provided with a chute, and the other square sub-board 31 is slidably arranged in the chute. Through the above arrangement, the adjustment stability of the two square sub-plates 31 and the airtightness after adjustment can be improved.
于本实施例中，第一封板20和第二封板30均包括遮光板和隔音层，隔音层设置于遮光板的内侧。结构简单，且遮光隔音的效果较好。遮光板为黑色不锈钢板，材质常规，且成本较低。隔音层为聚酯纤维隔音棉，隔音效果较好，且成本较低。In this embodiment, both the first sealing plate 20 and the second sealing plate 30 include a light-shielding plate and a sound-insulating layer, and the sound-insulating layer is disposed inside the light-shielding plate. The structure is simple, and the effect of shading and sound insulation is better. The shading plate is a black stainless steel plate, the material is conventional, and the cost is low. The sound insulation layer is polyester fiber sound insulation cotton, which has good sound insulation effect and low cost.
于本实施例中，该伸缩式遮光隔音的动物行为学实验箱体还包括显示屏(图中未示出)，显示屏设置于框架10内。显示屏既能够对箱体内进行照亮，还能够显示多种图案，以测试箱体内动物的反应。In this embodiment, the retractable light-shielding and sound-insulating animal behavior experiment box further includes a display screen (not shown in the figure), and the display screen is arranged in the frame 10 . The display screen can not only illuminate the box, but also display various patterns to test the reaction of the animals in the box.
于本实施例中，该伸缩式遮光隔音的动物行为学实验箱体还包括万向轮(图中未示出)，多个万向轮设置于框架10的底部。通过设置万向轮，以便于对实验箱进行移动，以移动到合适的实验位置。In this embodiment, the telescopic light-shielding and sound-proof animal behavior experiment box also includes universal wheels (not shown in the figure), and a plurality of universal wheels are arranged at the bottom of the frame 10 . By setting universal wheels, it is convenient to move the experimental box to a suitable experimental position.
本申请实施例提供的伸缩式遮光隔音的动物行为学实验箱体的使用原理如下：The principle of use of the telescopic light-shielding and sound-proof animal behavior experiment box provided in the embodiment of the present application is as follows:
根据实验对象对拼接成框架10的杆件11的长度进行调节，同时第一封板20的四块三角形子板21和第二封板30的两块方形子板31随着杆件11的长度做适应性调节，以将伸缩式遮光隔音的动物行为学实验箱体的尺寸调节到合适的大小；用与第一封板20相同材质的盖板将底部开口的中部镂空口盖住；将行为箱从顶部开口的中部镂空口放入到伸缩式遮光隔音的动物行为学实验箱体内；最后用与第一封板20相同材质的另一块盖板将顶部开口的中部镂空口盖住，从而为行为箱提供一个密封的实验环境。According to the experimental object, the length of the rods 11 spliced into the frame 10 is adjusted, and the four triangular sub-plates 21 of the first cover 20 and the two square sub-plates 31 of the second cover 30 are adjusted with the length of the rods 11. Make adaptive adjustments to adjust the size of the telescopic light-shielding and sound-proof animal behavior experiment box to an appropriate size; cover the hollow opening in the middle of the bottom opening with a cover plate of the same material as the first sealing plate 20; The box is put into the retractable light-shielding and sound-proof animal behavior experiment box from the middle hollow opening of the top opening; finally, another cover plate of the same material as the first sealing plate 20 is used to cover the middle hollow opening of the top opening, thereby providing The behavior box provides a sealed experimental environment.
行为箱一般为圆柱形，行为箱的底面一般被划分为中部的方形区域以及方形区域周边的四个扇形区域，实验时将实验动物(通常为小鼠)放入行为箱内一定时间，并记录实验动物处于中央方向区域以及周边扇形区域的驻留时间、总路程和平均速度来分析实验动物的自发活动以及焦虑行为。The behavior box is generally cylindrical, and the bottom surface of the behavior box is generally divided into a square area in the middle and four fan-shaped areas around the square area. During the experiment, put the experimental animals (usually mice) into the behavior box for a certain period of time, and record The dwell time, total distance and average speed of the experimental animals in the central direction area and the surrounding fan-shaped area were used to analyze the spontaneous activities and anxiety behaviors of the experimental animals.

Claims (10)

  1. 一种动物行为学实验箱体，包括：An animal behavior experiment box, comprising:
    框架(10)，由多个杆件(11)拼接而成，且所述杆件(11)的长度能够调节，所述框架(10)具有顶部开口、底部开口以及多个侧部开口；The frame (10) is spliced by a plurality of rods (11), and the length of the rods (11) can be adjusted, and the frame (10) has a top opening, a bottom opening and a plurality of side openings;
    多个封板，分别封盖于所述顶部开口、所述底部开口以及所述多个侧部开口处，且所述封板的大小能够随所述杆件(11)的长度调节而调节，所述封板设置为遮光和隔音。A plurality of sealing plates are respectively sealed at the top opening, the bottom opening and the plurality of side openings, and the size of the sealing plates can be adjusted according to the length of the rod (11), The sealing plate is set for light-shielding and sound-proofing.
  2. 根据权利要求1所述的动物行为学实验箱体，其中，所述杆件(11)包括第一杆件(111)和第二杆件(112)，所述第一杆件(111)和所述第二杆件(112)中的一个上设置有滑动腔，所述第一杆件(111)和所述第二杆件(112)中的另一个的一端滑动连接于所述滑动腔中。The animal behavior experiment box according to claim 1, wherein the rod (11) comprises a first rod (111) and a second rod (112), and the first rod (111) and One of the second rods (112) is provided with a sliding cavity, and one end of the other of the first rod (111) and the second rod (112) is slidably connected to the sliding cavity middle.
  3. 根据权利要求1所述的动物行为学实验箱体，其中，封盖于所述顶部开口和所述底部开口的封板为第一封板(20)，所述第一封板(20)包括四块三角形子板(21)，所述四块三角形子板(21)分别设置于所述顶部开口或所述底部开口的四个角的位置，且每相邻两块三角形子板(21)之间能够相对滑动，所述三角形子板(21)的两侧面分别与形成所述顶部开口或所述底部开口的角位置的两个杆件(11)连接，所述四块三角形子板(21)的底面共同围合形成中部镂空口。The animal behavior experiment box according to claim 1, wherein the sealing plate covering the top opening and the bottom opening is a first sealing plate (20), and the first sealing plate (20) includes Four triangular sub-plates (21), the four triangular sub-plates (21) are respectively arranged at the four corners of the top opening or the bottom opening, and every two adjacent triangular sub-plates (21) The two sides of the triangular sub-plates (21) are respectively connected with two rods (11) forming the corner positions of the top opening or the bottom opening, and the four triangular sub-plates ( 21) and the bottom surfaces together form a hollow opening in the middle.
  4. 根据权利要求1所述的动物行为学实验箱体，其中，封盖于所述侧部开口的封板为第二封板(30)，所述第二封板(30)包括两块方形子板(31)，所述两块方形子板(31)左右分布，且所述两块方形子板(31)能够相对滑动。The animal behavior experiment box according to claim 1, wherein the sealing plate covering the side opening is a second sealing plate (30), and the second sealing plate (30) comprises two square pieces plate (31), the two square sub-plates (31) are distributed left and right, and the two square sub-plates (31) can slide relatively.
  5. 根据权利要求4所述的动物行为学实验箱体，其中，所述两块方形子板(31)中，一块方形子板(31)上开设有滑槽，另一块方形子板(31)滑动设置于所述滑槽中。The animal behavior experiment box according to claim 4, wherein, among the two square sub-boards (31), one square sub-board (31) is provided with a chute, and the other square sub-board (31) slides set in the chute.
  6. 根据权利要求1所述的动物行为学实验箱体，其中，所述封板包括遮光板和隔音层，所述隔音层设置于所述遮光板的内侧。The animal behavior experiment box according to claim 1, wherein the sealing plate comprises a light-shielding plate and a sound-insulating layer, and the sound-insulating layer is arranged on the inner side of the light-shielding plate.
  7. 根据权利要求6所述的动物行为学实验箱体，其中，所述遮光板为黑色不锈钢板。The animal behavior experiment box according to claim 6, wherein the shading plate is a black stainless steel plate.
  8. 根据权利要求6所述的动物行为学实验箱体，其中，所述隔音层为聚酯纤维隔音棉。The animal behavior experiment box according to claim 6, wherein the sound insulation layer is polyester fiber sound insulation cotton.
  9. 根据权利要求1-8任一项所述的动物行为学实验箱体，还包括显示屏，所述显示屏设置于所述框架(10)内。The animal behavior experiment box according to any one of claims 1-8, further comprising a display screen arranged in the frame (10).
  10. 根据权利要求1-8任一项所述的动物行为学实验箱体，还包括多个万向 轮，所述多个万向轮设置于所述框架(10)的底部。The animal behavior experiment box according to any one of claims 1-8, further comprising a plurality of universal wheels, and the plurality of universal wheels are arranged at the bottom of the frame (10).
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