WO2021256166A1 - 捕集器具 - Google Patents
捕集器具 Download PDFInfo
- Publication number
- WO2021256166A1 WO2021256166A1 PCT/JP2021/019293 JP2021019293W WO2021256166A1 WO 2021256166 A1 WO2021256166 A1 WO 2021256166A1 JP 2021019293 W JP2021019293 W JP 2021019293W WO 2021256166 A1 WO2021256166 A1 WO 2021256166A1
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- WO
- WIPO (PCT)
- Prior art keywords
- rotating body
- liquid
- droplet
- container
- rotation axis
- Prior art date
Links
- 238000001816 cooling Methods 0.000 claims abstract description 61
- 239000007788 liquid Substances 0.000 claims description 174
- 244000052769 pathogen Species 0.000 description 38
- 230000001717 pathogenic effect Effects 0.000 description 36
- 230000002093 peripheral effect Effects 0.000 description 22
- 241000700605 Viruses Species 0.000 description 15
- 239000000463 material Substances 0.000 description 8
- 208000015181 infectious disease Diseases 0.000 description 7
- 238000001514 detection method Methods 0.000 description 5
- 239000010419 fine particle Substances 0.000 description 5
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- 238000000034 method Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000002458 infectious effect Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- 239000008055 phosphate buffer solution Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 208000003322 Coinfection Diseases 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
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- 230000001141 propulsive effect Effects 0.000 description 2
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- 229920005989 resin Polymers 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/1065—Filters in a path in the expiratory path
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/22—Devices for withdrawing samples in the gaseous state
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0083—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/1055—Filters bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7509—General characteristics of the apparatus with filters for virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7518—General characteristics of the apparatus with filters bacterial
Definitions
- This disclosure relates to a collection device that introduces exhaled breath containing an object such as a pathogen and collects the object in exhalation into a liquid.
- Patent Document 1 a method of sampling fine particles in the air using a device that utilizes the inertia and centrifugal force of the fine particles is known (see, for example, Patent Document 1 and Patent Document 2).
- the exhaled breath of a patient infected with an infectious virus such as influenza virus contains an infectious virus. Then, the infectious virus in the exhaled breath of the patient is considered to spread in the form of particles (droplets or droplet nuclei) in the air and cause droplet infection or airborne infection.
- Patent Document 1 Conventionally, a device for collecting components in the exhaled breath of the human body has been developed (see, for example, Patent Document 1).
- the device of Patent Document 1 includes a collection tube formed in a spiral shape, a collection bottle connected to a dropping port of the collection tube, and a cooling container for cooling the collection tube.
- a virus collecting tool capable of collecting a virus contained in a patient's exhaled breath and using it as a sample for diagnosis or research has also been devised (see, for example, Patent Document 2).
- the virus collecting tool of Patent Document 2 includes a main body, an exhalation introduction unit that introduces the patient's exhaled breath, a trap unit that captures the virus contained in the patient's exhaled breath, and a suction unit that sucks a gas component including the patient's exhaled breath. It is equipped with.
- Patent Document 2 In the virus collecting tool of Patent Document 2, the exhaled breath of the patient is introduced into the exhaled breath introduction portion having a constricted portion, and the water vapor in the exhaled breath is removed by utilizing the decompressed state when the exhaled breath is released from the opening of the constricted portion. It condenses and liquefies, and the virus contained in the liquid is introduced into the separation medium placed in the trap portion. However, it is difficult to reliably take the virus into the trap unit. Further, Patent Document 2 also discloses that a member called a cylindrical penetrating cloth is inserted between the opening of the constricted portion and the trap portion to collect a liquid containing a virus. However, it takes time and effort to separate the liquid containing the virus by removing the penetrating cloth and centrifuging it.
- the present disclosure has been made in view of the above problems, and provides a collection device capable of easily collecting an object in exhalation into a liquid.
- the collecting device is a container into which exhaled air containing an object is introduced, and cooling that lowers the temperature of the exhaled air introduced into the container to generate droplets containing the object.
- a portion and a rotating body provided in the container and rotating, the rotating body has a first blade portion protruding in a direction intersecting the rotation axis of the rotating body, and the first blade portion is It has at least one of a filter portion for capturing the droplet and a plate surface portion through which the droplet does not pass.
- the collection device can easily collect an object in exhaled breath in a liquid. Further advantages and effects in one aspect of the present disclosure will be apparent from the specification and drawings. Such advantages and / or effects are provided by some embodiments and the features described in the specification and drawings, respectively, but not all need to be provided in order to obtain one or more identical features. There is no.
- FIG. 1 is a perspective view showing a collecting device according to the first embodiment.
- FIG. 2 is a sectional view taken along line II-II of FIG.
- FIG. 3 is a cross-sectional view taken along the line III-III of FIG.
- FIG. 4 is a cross-sectional view showing a collecting device according to the second embodiment as viewed from the left.
- FIG. 5 is a cross-sectional view showing a collecting device according to the second embodiment as viewed from the front.
- FIG. 6 is a cross-sectional view showing a collecting device according to the third embodiment as viewed from the left.
- FIG. 7 is a side view showing the collecting device according to the fourth embodiment as viewed from the left.
- FIG. 8 is a side view showing the collecting device according to the fifth embodiment.
- the collection device according to the present disclosure is not intended to be limited to the configurations described in the embodiments and / or drawings described below, and includes configurations equivalent thereto.
- FIG. 1 is a perspective view showing a collecting device 10 according to the first embodiment.
- FIG. 2 is a sectional view taken along line II-II of FIG.
- FIG. 3 is a cross-sectional view taken along the line III-III of FIG.
- the collection device 10 according to the first embodiment will be described with reference to FIGS. 1 to 3.
- FIG. 1 in order to avoid complicating the drawing, the drawing of the collected liquid 16 (described later) is omitted.
- the first blade portions 44b and 44d (described later) are not shown in order to avoid complicating the drawings.
- the introduction pipe 20 (described later) side when viewed from the peripheral wall portion 24 (described later) of the main body 18 (described later), the introduction pipe 20 (described later) side will be referred to as the front and the exhaust pipe 22 (described later) side will be described as the rear (FIGS. 1 and FIG. See arrow 2).
- the left wall portion 26 (described later) side is defined as the left side and the right wall portion 28 (described later) side is defined as the right side when viewed from the peripheral wall portion 24 (see the arrows in FIGS. 1 and 3). ..
- the side opposite to the flow path A will be described as downward and the side opposite to the flow path A will be described as downward when viewed from the shaft body 42 (described later) (see the arrows in FIGS. 1 to 3).
- the front-back direction, the left-right direction, and the up-down direction intersect each other vertically.
- the collection device 10 is a device that collects the exhaled object 1 in a liquid.
- the object 1 includes pathogens, viruses, pollen, particulate matter, and the like.
- the collection device 10 includes a container 12, a rotating body 14, a collection liquid 16, and a cooling unit 100.
- a container 12 a rotating body 14 a collection liquid 16, and a cooling unit 100.
- the container 12 is a container into which a gas such as exhaled breath is introduced.
- the container 12 holds the collected liquid 16 in the container 12 and has a flow path A through which the gas passes above the held collected liquid 16.
- the container 12 rotatably supports the rotating body 14 around the rotation axis X in the container 12 (see arrow Y in FIG. 2).
- the rotation axis X extends in the left-right direction. In other words, the rotation axis X extends in a direction perpendicular to the vertical direction.
- the rotation axis X does not have to extend in the direction perpendicular to the vertical direction, and may extend in the direction intersecting the vertical direction.
- the container 12 has a main body 18, an introduction pipe 20, and an exhaust pipe 22.
- the main body 18 is a portion that holds the collected liquid 16 and is a portion that rotatably supports the rotating body 14 around the rotation axis X.
- the main body 18 has a cylindrical shape and has a peripheral wall portion 24, a left wall portion 26, and a right wall portion 28.
- the main body 18 has a space D inside which accommodates the rotating body 14.
- the peripheral wall portion 24 is formed along the rotation axis X, extends in the left-right direction, and has a cylindrical shape.
- the peripheral wall portion 24 is provided so as to surround the rotating body 14.
- the peripheral wall portion 24 has a hole portion 30 and a hole portion 32 penetrating the peripheral wall portion 24 in the front-rear direction above the rotation axis X.
- the hole portion 30 is provided in front of the rotation axis X, and the hole portion 32 is provided behind the rotation axis X.
- the hole 30 and the hole 32 face each other in the front-rear direction.
- the left wall portion 26 and the right wall portion 28 each extend in a direction perpendicular to the rotation axis X and have a substantially disk shape.
- the left wall portion 26 and the right wall portion 28 face each other in the left-right direction.
- the left wall portion 26 is connected to the left end portion of the peripheral wall portion 24 so as to cover the rotating body 14 from the left side.
- the left wall portion 26 penetrates the central portion of the left wall portion 26 in the left-right direction and has a circular hole portion 34.
- the right wall portion 28 is connected to the right end portion of the peripheral wall portion 24 so as to cover the rotating body 14 from the right side.
- the right wall portion 28 penetrates the central portion of the right wall portion 28 in the X direction of the rotation axis and has a circular hole portion 36.
- Space D is formed by a peripheral wall portion 24, a left wall portion 26, and a right wall portion 28.
- the collecting liquid 16 is stored in a part of the space D, and a part of the rotating body 14 is immersed in the collecting liquid 16.
- the portion of the space D located above the collected liquid 16 constitutes a part of the flow path A.
- the introduction pipe 20 is a portion that introduces the exhaled air of the user who uses the collection device 10 or a gas such as air around the collection device 10, and is connected to the main body 18.
- the user is, for example, a patient having a pathogen.
- the introduction pipe 20 has a cylindrical shape and communicates with the space D in the main body 18.
- the introduction pipe 20 has a cylindrical portion 38 and a conical tubular portion 40.
- the cylindrical portion 38 extends in the front-rear direction and has a cylindrical shape.
- the cylindrical portion 38 is connected to the peripheral wall portion 24 so as to communicate with the hole portion 30.
- the conical cylinder portion 40 gradually widens toward the front, and is conical and cylindrical.
- the conical cylinder portion 40 is connected to an end portion of the cylindrical portion 38 opposite to the peripheral wall portion 24.
- the exhaust pipe 22 is a portion that discharges the gas introduced from the introduction pipe 20, and is connected to the main body 18 on the opposite side of the introduction pipe 20.
- the exhaust pipe 22 extends in the front-rear direction and has a cylindrical shape.
- the exhaust pipe 22 is connected to the peripheral wall portion 24 so as to communicate with the hole portion 32.
- the container 12 has a flow path A composed of an introduction pipe 20, a main body 18, and an exhaust pipe 22.
- the gas introduced into the container 12 flows through the flow path A.
- the gas introduced into the introduction pipe 20 passes through the conical cylinder portion 40 and the cylinder portion 38 (see the arrow B1 in FIG. 2), and flows into the main body 18 from the hole portion 30.
- the gas that has flowed into the main body 18 passes above the collected liquid 16 and flows from the hole 32 into the exhaust pipe 22 (see arrow B2 in FIG. 2). Then, the gas is exhausted from the exhaust pipe 22.
- the container 12 has a flow path A above the collected liquid 16 so that the gas flows in the front-rear direction.
- the container 12 has a flow path A above the collected liquid 16 so that the gas flows in the direction perpendicular to the rotation axis X when viewed from the vertical direction.
- the container 12 does not have to have the flow path A so that the gas flows in the direction perpendicular to the rotation axis X when viewed from the vertical direction.
- the container 12 does not have to have the rotation axis when viewed from the vertical direction.
- the flow path A may be provided so that the gas flows in the direction intersecting with X.
- the rotating body 14 is provided in the container 12 and rotates.
- the rotating body 14 is supported by the container 12 so as to be rotatable around the rotation axis X.
- the rotating body 14 has a shaft body 42 and a plurality of first blade portions 44a to 44h.
- the shaft body 42 extends in the left-right direction and is columnar.
- the axis of the shaft body 42 coincides with the rotation axis X.
- the shaft body 42 is provided at the center of the cylinder of the main body 18. Specifically, the left end portion of the shaft body 42 is rotatably fitted in the hole portion 34 of the left wall portion 26, and the right end portion of the shaft body 42 is rotatable in the hole portion 36 of the right wall portion 28. It fits. As a result, the shaft body 42 is supported by the main body 18 so as to be rotatable around the rotation axis X.
- the plurality of first blade portions 44a to 44h project in a direction intersecting the rotation axis X of the rotating body 14, and are attached to the outer peripheral surface of the shaft body 42 at equal intervals around the rotating axis X.
- the plurality of first blade portions 44a to 44h project outward from the outer peripheral surface of the shaft body 42 in the radial direction of the shaft body 42, and are arranged at equal intervals in the circumferential direction of the shaft body 42.
- the plurality of first blade portions 44a to 44h can rotate around the rotation axis X together with the shaft body 42.
- the first blade portion 44a has a filter portion 46 and a frame portion 48.
- the filter unit 46 extends in the left-right direction and extends in the direction intersecting the rotation axis X, and has a quadrangular plate shape.
- the filter unit 46 does not have to have a rectangular plate shape.
- the filter portion 46 projects in a direction intersecting the rotation axis X, and is connected to the outer peripheral surface of the shaft body 42.
- the filter unit 46 rotates around the rotation axis X.
- the filter unit 46 captures the object 1 in the gas by coming into contact with the gas.
- the filter unit 46 permeates the gas and captures the object 1 in the permeated gas.
- the filter unit 46 captures the droplet 3 generated by the cooling unit 100.
- the filter unit 46 captures the droplet 3 by contacting the droplet 3 generated by the cooling unit 100 and floating in the container 12.
- the filter portion 46 is formed in a mesh pattern, for example.
- various known filters capable of capturing the object 1 in the gas can be used.
- various known filters capable of capturing the droplet 3 can be used.
- a filter using a non-woven fabric can be used.
- a filter having a porosity such that when a gas flows through the flow path A, the gas is permeated and the rotating body 14 rotates around the rotation axis X in response to the gas is used. Can be done.
- the filter portion 46 projects upward from the liquid level 17 of the collected liquid 16 and is inside the flow path A. Is located in. Specifically, when the filter unit 46 is located directly above the rotation axis X, a part of the filter unit 46 is in the flow path A, and the other part of the filter unit 46 is captured. It is immersed in the liquid collector 16. When the filter portion 46 is located directly above the rotation axis X, the filter portion 46 overlaps the hole portion 30 and the hole portion 32 in the front-rear direction. On the other hand, when the filter unit 46 is located directly below the rotation axis X (position of the first blade unit 44e in FIG.
- the filter portion 46 is configured to be movable from a position in the flow path A to a position where the rotating body 14 is immersed in the collected liquid 16 by rotating the rotating body 14 around the rotation axis X.
- the filter unit 46 moves from the position where the rotating body 14 is not immersed in the collecting liquid 16 to the position where it is immersed in the collecting liquid 16 by rotating the rotating body 14 around the rotation axis X.
- the filter unit 46 rotates around the rotation axis X by rotating the rotating body 14 around the rotation axis X, and moves from a position in the flow path A to a position where the rotating body 14 is immersed in the collected liquid 16. It is configured to be possible. More specifically, as the rotating body 14 rotates around the rotation axis X, the portion of the filter portion 46 that was present in the flow path A is immersed in the collected liquid 16. That is, as the rotating body 14 rotates around the rotation axis X, the portion of the filter portion 46 that has not been immersed in the collecting liquid 16 is immersed in the collecting liquid 16.
- the frame portion 48 is open to the shaft body 42 side and has a substantially U-shape, and is provided along the edge portion of the filter portion 46.
- the frame portion 48 is attached to the outer peripheral surface of the shaft body 42.
- the frame portion 48 is provided so as to sandwich the edge portion of the filter portion 46.
- the frame portion 48 is provided with a gap from the inner surface of the main body 18. Specifically, in the direction perpendicular to the rotation axis X, the frame portion 48 is provided with a gap from the inner surface of the peripheral wall portion 24. In the left-right direction, the frame portion 48 is provided with a gap from the inner surface of the left wall portion 26 and is provided with a gap from the inner surface of the right wall portion 28.
- each of the first blade portions 44b to 44h has the same configuration as the first blade portion 44a, a detailed description of the first blade portions 44b to 44h will be made by referring to the above-mentioned description of the first blade portion 44a. Is omitted.
- the collecting liquid 16 is a liquid for collecting the object 1 and is filled inside the main body 18. Specifically, the collected liquid 16 is filled inside the main body 18 so that the liquid level 17 of the collected liquid 16 is formed above the rotation axis X and above the shaft body 42. ing. The collected liquid 16 is filled inside the main body 18 so that the liquid surface 17 of the collected liquid 16 is formed below the hole 30 and the hole 32. In this way, the collected liquid 16 may be put in to a height that does not spill from the introduction pipe 20 and the exhaust pipe 22.
- the cooling unit 100 is a portion that cools the exhaled air introduced into the container 12 to lower the temperature of the exhaled air to atomize the exhaled air and generate droplets 3 containing the object 1. Specifically, the cooling unit 100 cools the exhaled air flowing through the introduction pipe 20 to generate a droplet 3 containing the object 1.
- the cooling unit 100 includes a housing 101, a cooling source 102, a power switch 103, and a heat transfer rod 104.
- the housing 101 is attached to the cylindrical portion 38.
- a cooling source 102 is included in the housing 101.
- the cooling source 102 is a member for cooling the exhaled air introduced into the container 12.
- a cooled material such as ice or a cooling agent, an instantaneous cooling material that absorbs heat by applying an impact, a power supply type Pelche element, or the like may be used.
- the cooling source 102 lowers the temperature of the exhaled air introduced into the container 12 via the heat transfer rod 104. Specifically, the cooling source 102 cools the heat transfer rod 104 to lower the temperature of the heat transfer rod 104, thereby lowering the temperature of the exhaled air introduced into the container 12 and passing in the vicinity of the heat transfer rod 104. Decrease.
- the cooling source 102 lowers the temperature of the heat transfer rod 104 so that the temperature of the exhaled air introduced into the container 12 becomes the dew point or lower.
- the cooling source 102 lowers the temperature of the heat transfer rod 104 so as to lower the temperature of the exhaled air introduced into the container 12 by 1 ° C.
- the power supply switch 103 is used. That is, by turning on the power switch 103, the power supply type cooling source 102 is operated to cool the exhaled air.
- the power supply switch 103 is not always necessary.
- the heat transfer rod 104 is formed of a material having thermal conductivity and has a rod shape. One end of the heat transfer rod 104 is connected to the cooling source 102, and as described above, the heat transfer rod 104 is cooled by the cooling source 102. The other end of the heat transfer rod 104 is arranged in the introduction pipe 20, and by cooling the heat transfer rod 104, the exhaled air flowing in the introduction pipe 20 is cooled, and the temperature of the exhaled air is lowered.
- a heat transfer member having a shape such as a plate, a wire, or a sphere made of a material having thermal conductivity can also be used.
- the exhaled air cooled by the cooling unit 100 is saturated with water vapor even with a slight temperature difference due to the high humidity of the exhaled air, and starts to condense to cover the fine particles in the exhaled air.
- the fine particles contained in the exhaled breath become droplets 3 and the apparent size is greatly increased. That is, when the temperature of the exhaled air decreases, the exhaled air is condensed with the object 1 in the exhaled air as a nucleus, and a droplet 3 containing the object 1 is generated.
- the droplet 3 containing the object 1 collides with the rotating body 14 by inertia together with the flow of exhaled air that has not been dropletized, and is collected.
- the droplet 3 containing the object 1 is swept away by the exhaled air introduced into the container 12 that has not been made into droplets, flows into the space D in the main body 18, and is housed in the space D. It adheres to the rotating body 14. Specifically, the droplet 3 containing the object 1 comes into contact with the fiber-filled filter unit 46 and is captured by the filter unit 46.
- the mechanism of collection is not limited to collection by inertia, but may be collection by other mechanisms such as collection by diffusion.
- each of the first blade portions 44a to 44h of the rotating body 14 may be a filter portion 46 filled with fibers as described above, or may be a simple plate surface. That is, each of the first blade portions 44a to 44h may have a plate surface portion through which the droplets do not pass, instead of the filter portion 46. In this case, when the droplet 3 comes into contact with the plate surface portion, the droplet 3 adheres to the plate surface portion, and the plate surface portion captures the droplet 3.
- each of the first blade portions 44a to 44h may have both a filter portion 46 and a plate surface portion.
- the first blade portion 44a may be provided with a filter portion on the outer portion in the radial direction and a plate surface portion on the inner portion in the radial direction.
- Each of the first blade portions 44b to 44h may be provided with a filter portion on the outer portion in the radial direction and a plate surface portion on the inner portion in the radial direction.
- each of the first blade portions 44a to 44h has at least one of the filter portion 46 and the plate surface portion, and at least one of the filter portion 46 and the plate surface portion receives the droplet 3 generated by the cooling unit 100.
- the plate surface portion is the surface of a plate-shaped member formed of metal, resin, or the like. In the second to fifth embodiments described later, as described above, the plate surface portion may be provided instead of the filter portion 46.
- the rotating body 14 that has captured the droplet 3 blows the droplet 3 outward by centrifugal force while rotating, and the blown droplet 3 adheres to the inner surface of the container 12 in a state containing the object 1.
- the droplet 3 attached to the inner surface of the container 12 moves toward the lower part of the container 12 by gravity and mixes with the collected liquid 16.
- the object 1 contained in the droplet 3 is collected in the collecting liquid 16.
- the above-mentioned plate surface portion is provided instead of the filter portion 46. In this way, the exhaled object 1 can be collected in the liquid.
- the filter unit 46 moves from a position where it is not immersed in the collection liquid 16 to a position where it is immersed in the collection liquid 16.
- the droplet 3 that is not blown off and remains captured by the filter unit 46 mixes with the collection liquid 16, and the object 1 contained in the droplet 3 is mixed. Is collected in the collection liquid 16.
- the above-mentioned plate surface portion is provided instead of the filter portion 46. In this way, the exhaled object 1 can be collected in the liquid.
- the container 12 holds the collected liquid 16
- the present invention is not limited to this, and the container 12 does not have to hold the collected liquid 16. That is, the container 12 does not have to be filled with the collected liquid 16.
- the rotating body 14 that has collided with the droplet 3 and captured the droplet 3 sifts the droplet 3 while rotating, and the sifted droplet 3 contains fine particles (object 1) as a solution. It is deposited on the bottom (lower part) of the container 12 in a contained state. That is, when the rotating body 14 that has captured the droplet 3 rotates, the droplet 3 captured by the rotating body 14 is blown outward by centrifugal force and accumulated in the lower part of the container 12.
- the liquid containing the object 1 is obtained by accumulating the droplet 3 containing the object 1 in the lower part of the container 12. That is, the object 1 can be collected in the liquid. In this way, even if the container 12 does not hold the collected liquid 16, the exhaled object 1 can be collected in the liquid. Similarly, in the second to fourth embodiments described later, the container 12 (12a) does not have to hold the collected liquid 16.
- the collection device 10 attaches the collection device 10 to the patient. Specifically, the collection device 10 is attached to the patient so that the patient's mouth is covered with the conical tube portion 40 of the introduction tube 20.
- the collection device 10 is attached to the patient, if there is a gap between the conical tube 40 and the periphery of the patient's mouth, the patient's exhaled breath leaks to the outside, and a small amount of pathogen present in the patient's exhaled breath. May not be collected sufficiently. Therefore, even if a polyurethane sheet is processed into a tape and attached to the opening 41 on the front side of the conical tube 40 to fill the gap between the conical tube 40 and the periphery of the patient's mouth. good.
- the portion connecting the conical cylinder portion 40 and the main body 18, for example, the cylindrical portion 38 may be a flexible rubber tube.
- the direction of the conical tube portion 40 can be easily changed, so that the patient can more reliably send the exhaled breath into the main body 18 of the collection device 10 without taking an unreasonable posture.
- the patient After wearing the collection device 10, the patient takes in air into the lungs through the nose, continues to exhale through the mouth, and blows exhaled air into the main body 18 through the introduction tube 20.
- the required amount of exhaled air has been taken into the container 12 by means such as a flow meter, and if the required amount is not reached, urge the patient to breathe in again. Is also valid.
- the amount of exhaled breath required for the test can be calculated in advance, and the exhaled breath required for the test can be more reliably introduced into the container 12 according to the result.
- the inside of the main body 18 is pre-filled with the collected liquid 16.
- the collecting liquid 16 By using, for example, physiological saline as the collecting liquid 16, it is possible to make it difficult to damage the pathogen to be collected.
- the amount of the collected liquid 16 is, for example, about 5 mL. If the main body 18 is tilted significantly toward the introduction pipe 20 or the exhaust pipe 22, the collected liquid 16 may leak from the main body 18, so the main body 18 may be fixed so as not to tilt.
- the rotating body 14 rotates around the rotation axis X due to the wind pressure of the exhaled breath blown by the patient, and the exhaled air passes through the filter portion 46 of the rotating body 14.
- a part of the exhaled air is cooled by the cooling unit 100 to become droplets 3, which are flowed by the exhaled air and come into contact with the filter unit 46 and are captured by the filter unit 46. That is, the exhaled air comes into contact with the filter unit 46 in a state containing the droplet 3.
- the rotating body 14 can be easily rotated by exhalation by selecting a filter unit 46 having a porosity equal to or less than a degree at which resistance is felt by the wind pressure of exhaled air when the exhaled air or the like is blown.
- a silicone-based soft member may be used for a portion (contact portion 51 (described later)) in contact with the inner surface of the main body 18a constituting A.
- the soft member is adjusted to a position where the rotation of the rotating body 14a cannot be stopped and the exhaled air can be prevented from leaking from the gap between the rotating body 14a and the main body 18a and losing the propulsive force of the rotation of the rotating body 14a. To install.
- one or a plurality of the first blade portions included in the first blade portions 44a to 44h may be one or a plurality of the first blade portions. It may be changed to the second blade portion (in the example of FIG. 6, the second blade portion 52a, 52c, 52e, 52g).
- the material of each of the one or a plurality of second blade portions may be a Teflon (registered trademark) plate material that is less likely to allow gas to pass through than the filter portion 46.
- the rotating body 14 rotates, and the exhaled air flows to the exhaust pipe 22 while sequentially contacting the filter portion 46 of the first blade portion 44a to the filter portion of the first blade portion 44h.
- the plurality of first blade portions 44a to 44h move into the flow path A in order, so that the exhaled air easily hits the first blade portions 44a to 44h and the rotating body 14 can be easily rotated.
- the object 1 such as a pathogen contained in the exhaled breath is attached to the surface of the filter unit 46, and when the filter unit 46 is immersed in the collection liquid 16 due to the rotation of the rotating body 14, the pathogen is present at that time.
- the object 1 such as the above is separated and collected in the collection liquid 16.
- the droplet 3 contained in the exhaled breath is attached to the surface of the filter unit 46, and is sifted off by the centrifugal force caused by the rotation of the rotating body 14 and mixed with the collected liquid 16 or the filter unit.
- the 46 When the 46 is immersed in the collection liquid 16, it mixes with the collection liquid 16, and the object 1 contained in the droplet 3 is separated and collected in the collection liquid 16.
- the patient blows the exhaled air to generate droplets 3 and rotate the rotating body 14 installed inside the main body 18.
- the patient's exhaled breath contains an object 1 such as a pathogen
- the exhaled breath passes through or touches the filter portion 46 of the rotating body 14
- the surface of the filter portion 46 is covered with the object 1 such as a pathogen and / /.
- the droplet 3 containing the object 1 is captured.
- the captured object 1 such as a pathogen touches the collecting liquid 16 and leaves the filter unit 46 when the rotating body 14 rotates, and is separated and collected by the collecting liquid 16.
- the captured droplet 3 is either sifted off by centrifugal force and mixed with the collected liquid 16 by the rotation of the rotating body 14, or the filter unit 46 is immersed in the collected liquid 16 to collect the collected liquid. It mixes with 16 and the object 1 contained in the droplet 3 is separated and collected in the collecting liquid 16.
- the object 1 in the gas can be collected in the liquid.
- the collection liquid 16 in which the object 1 is collected is collected, and the presence or absence of a pathogen is inspected with a pathogen detection device. If the collected collection liquid 16 contains a pathogen, the pathogen can be collected by the pathogen detection device. It is also possible to connect the collection device 10 to the pathogen detection device and automatically perform a series of operations from the introduction of the patient's breath to the inspection of the presence or absence of the pathogen.
- the collecting device 10 lowers the temperature of the container 12 into which the exhaled air containing the object 1 is introduced and the exhaled air introduced into the container 12, and includes the object 1.
- a cooling unit 100 for generating droplets 3 and a rotating body 14 provided in the container 12 and rotating are provided, and the rotating body 14 has one or a plurality of protrusions in a direction intersecting the rotation axis X of the rotating body 14.
- Each of the first blade portions 44a to 44h has one or a plurality of first blade portions 44a to 44h, and each of the first blade portions 44a to 44h has a filter portion 46 for capturing the droplet 3.
- the cooling unit 100 can generate a droplet 3 containing the object 1 in the exhaled breath. Since the rotating body 14 has a filter unit 46 for capturing the droplet 3, the generated droplet 3 can be captured by the rotating body 14. By rotating the rotating body 14, the droplet 3 captured by the rotating body 14 can be blown outward by centrifugal force. The blown droplets 3 accumulate in the container 12. By storing the droplet 3 containing the object 1 in the container 12, a liquid containing the object 1 can be obtained. In this way, when the exhaled breath is blown in, the object 1 can be easily collected in the liquid.
- the container 12 has a main body 18 having a space D inside for accommodating the rotating body 14, and an introduction pipe 20 connected to the main body 18 and communicating with the space D in the main body 18, and the cooling unit 100 has an introduction pipe. Cool the exhaled air flowing through 20.
- the exhaled air flowing through the introduction tube 20 can be cooled to generate the droplet 3, and the generated droplet 3 can be easily moved to the space D in the main body 18 together with the exhaled air. Since the rotating body 14 is housed in the space D in the main body 18, the droplet 3 moved to the space D in the main body 18 can be easily captured by the rotating body 14.
- the container 12 holds the collected liquid 16, and the filter unit 46 moves from a position where the rotating body 14 is not immersed in the collected liquid 16 to a position where the rotating body 14 is immersed in the collected liquid 16.
- the filter unit 46 can capture the droplet 3 contained in the exhaled breath at a position where it is not immersed in the collecting liquid 16.
- the droplet 3 captured by the filter unit 46 is mixed with the collection liquid 16, and the object 1 contained in the droplet 3 is the collection liquid 16. Collected inside. In this way, the object 1 can be easily collected in the collection liquid 16.
- the rotating body 14a rotates around the rotation axis X in a state where the respective ends of the first blade portions 50a to 50h are in contact with the inner surface of the container 12a, which is mainly the same as that of the first embodiment. It's different.
- FIG. 4 is a cross-sectional view showing a collecting device 10a according to the second embodiment as viewed from the left.
- FIG. 5 is a cross-sectional view showing a collecting device 10a according to the second embodiment as viewed from the front.
- the collection device 10a according to the second embodiment will be described with reference to FIGS. 4 and 5. In the following description, the differences from the collection device 10 according to the first embodiment will be mainly described.
- the collecting device 10a is different from the collecting device 10 in that it has a main body 18a different from the main body 18 and a first blade portion 50a to 50h different from the first blade portions 44a to 44h. ..
- the main body 18a is different from the main body 18 in that the lower portion of the main body 18a is recessed downward. This makes it easier to collect the object 1 in the collection liquid 16 at the lower part of the main body 18a.
- the frame portion 48a of each of the first blade portions 50a to 50h is different from the frame portion 48 of each of the first blade portions 44a to 44h.
- the frame portion 48a has a contact portion 51 in contact with the inner surface of the main body 18a of the container 12a.
- the contact portion 51 is in contact with the inner surface of the main body 18a constituting the flow path A in a state of being located in the flow path A.
- the contact portion 51 is in contact with the inner surface of the main body 18a even when it is immersed in the collected liquid 16.
- the inner surface of the main body 18a constituting the flow path A means a portion of the inner surface of the main body 18a located above the liquid level 17.
- the contact portion 51 is provided at the outer end portion of the frame portion 48a.
- the contact portion 51 gradually widens toward the outside and comes into contact with the inner surface of the main body 18a. Specifically, in the direction perpendicular to the rotation axis X, the contact portion 51 gradually widens outward and comes into contact with the inner surface of the peripheral wall portion 24a.
- the contact portion 51 gradually widens toward the left and comes into contact with the inner surface of the left wall portion 26a. In the left-right direction, the contact portion 51 gradually widens toward the right and comes into contact with the inner surface of the right wall portion 28a.
- a silicone-based soft member can be used as the contact portion 51.
- the rotating body 14a according to the second embodiment rotates around the rotation axis X in a state where the end portion (contact portion 51) of the first blade portion 50a is in contact with the inner surface of the main body 18a. Since each of the first blade portions 50b to 50h has the same configuration as the first blade portion 50a, a detailed description of the first blade portions 50b to 50h will be made by referring to the above description of the first blade portion 50a. Is omitted.
- the rotating body 14a is in a state where the respective ends (contact portions 51) of the first blade portions 50a to 50h are in contact with the inner surface of the container 12a. Rotate around the axis of revolution X.
- the rotating body 14a rotates around the rotation axis X in a state where each end portion (contact portion 51) of the first blade portions 50a to 50h is in contact with the inner surface of the main body 18a of the container 12a.
- the contact portion 51 is provided at the end of the frame portion 48a in the direction perpendicular to the rotation axis X and in the left-right direction, but in the direction perpendicular to the rotation axis X.
- the contact portion 51 may be provided at the end of the frame portion 48a, or the contact portion 51 may be provided at the end of the frame portion 48a in the left-right direction so as not to hinder the rotation of the rotating body 14a.
- the contact portion 51 may be provided.
- the contact portion 51 does not have to be gradually widened toward the outside.
- the third embodiment is mainly different from the first embodiment in that it has the second blade portions 52a, 52c, 52e, 52g instead of the first blade portions 44a, 44c, 44e, 44g. ..
- FIG. 6 is a cross-sectional view showing a collecting device 10b according to the third embodiment as viewed from the left.
- the collection device 10b according to the third embodiment will be described with reference to FIG. In the following description, the differences from the collection device 10 according to the first embodiment will be mainly described.
- the collection device 10b is different from the collection device 10 according to the first embodiment in that the container 12a is provided instead of the container 12.
- the collecting device 10b is different from the collecting device 10 according to the first embodiment in that it has the rotating body 14b instead of the rotating body 14.
- the rotating body 14b has a second blade portion 52a instead of the first blade portion 44a, a second blade portion 52c instead of the first blade portion 44c, a second blade portion 52e instead of the first blade portion 44e, and a first blade portion 44e. It differs from the rotating body 14 in that it has a second blade portion 52 g instead of the blade portion 44 g.
- the second blade portions 52a, 52c, 52e, and 52g project in a direction intersecting the rotation axis X, and are provided around the rotation axis X at equal intervals.
- the second blade portions 52a, 52c, 52e, 52g project outward from the outer peripheral surface of the shaft body 42 in the radial direction of the shaft body 42, and are attached to the outer peripheral surface of the shaft body 42.
- the second blade portion 52a extends in the left-right direction and extends in the direction perpendicular to the rotation axis X, and has a substantially quadrangular plate shape.
- the second blade portion 52a is in contact with the inner surface of the main body 18a of the container 12a.
- the second blade portion 52a is in contact with the inner surface of the main body 18a constituting the flow path A in a state of being located in the flow path A.
- the second blade portion 52a is in contact with the inner surface of the main body 18a even when it is immersed in the collecting liquid 16. More specifically, in the direction perpendicular to the rotation axis X, the end portion of the second blade portion 52a is in contact with the inner surface of the peripheral wall portion 24a. In the left-right direction, the end of the second blade portion 52a is in contact with the inner surface of the left wall portion 26a (see FIG. 5). In the left-right direction, the end of the second blade portion 52a is in contact with the inner surface of the right wall portion 28a.
- the second blade portion 52a is arranged alongside the first blade portions 44b, 44d, 44f, 44h around the rotation axis X.
- the rotating body 14b rotates around the rotation axis X
- the second blade portion 52a rotates around the rotation axis X.
- the rotating body 14b rotates around the rotation axis X with the end of the second blade portion 52a in contact with the inner surface of the main body 18a.
- a resin such as Teflon (registered trademark) can be used, and the second blade portion 52a is less likely to permeate the gas than the filter portion 46.
- the second blade portion 52a may be configured so as not to allow gas to pass through.
- the details of the second blade portions 52c, 52e, 52g can be referred to by referring to the above description of the second blade portion 52a. The explanation is omitted.
- Each of the first blade portions 44b, 44d, 44f, and 44h may be in contact with the inner surface of the main body 18a of the container 12a.
- the rotating body 14b rotates around the rotation axis X with the first blade portions 44b, 44d, 44f, and 44h each in contact with the inner surface of the main body 18a of the container 12a.
- the rotating body 14b protrudes in the direction intersecting the rotation axis X, and the second blade portions 52a, 52c, which are less likely to permeate the gas than the filter portion 46, It further has 52e and 52g.
- the rotating body 14b has second blade portions 52a, 52c, 52e, 52g that are less likely to permeate gas than the filter portion 46.
- the rotating body 14b is forced from the introduced exhaled breath. It becomes easy to receive, and the rotating body 14b can be easily rotated. Therefore, the object 1 in the gas and the droplet 3 containing the object 1 can be easily captured, and the object 1 can be more easily collected in the collecting liquid 16.
- the number of the second blades may be any number as long as the rotating body 14b rotates with the exhaled breath and the pathogen in the exhaled breath can be captured by the filter unit 46.
- the fourth embodiment is mainly different from the first embodiment in that the drive device 54 is further provided.
- FIG. 7 is a side view showing the collection device 10c according to the fourth embodiment as viewed from the left.
- the collection device 10c according to the fourth embodiment will be described with reference to FIG. 7. In the following description, the differences from the collection device 10 according to the first embodiment will be mainly described.
- the collection device 10c is different from the collection device 10 in that the drive device 54 is further provided.
- the collection device 10c is different from the collection device 10 in that the shaft body 42c protrudes outward from the left wall portion 26 in the left-right direction.
- the drive device 54 is a device that applies a rotational force to the rotating body 14c, and is a device that rotates the rotating body 14c around the rotation axis X.
- the drive device 54 includes a motor 56 and a belt 58.
- the belt 58 is hung around the shaft body 42c and the rotating shaft 60 of the motor 56.
- the rotating body 14c has a plurality of first blade portions 44a to 44h, but the rotating body may have one first blade portion.
- the collection device 10c further includes a drive device 54 for rotating the rotating body 14c around the rotation axis X.
- the motor 56 is connected to the shaft body 42c of the rotating body 14c, and the rotation of the motor 56 is transmitted to the shaft body 42c of the rotating body 14c.
- the rotating body 14c can be easily rotated. Therefore, the surrounding air can be easily introduced into the flow path A, and the object 1 such as a pathogen contained therein can be easily separated and collected in the collection liquid 16.
- the gas can be efficiently introduced and the object 1 in the gas can be efficiently collected.
- a gas is introduced to include an object such as a pathogen and an object in the filter portion of the rotating body. After capturing the droplets and separating and collecting the object such as a pathogen in the collecting liquid with the rotation of the rotating body, the collected liquid may be taken out and used for the inspection of the pathogen.
- a pipe for taking out the collected liquid is installed at the bottom of the main body, the liquid is sent by a pump, etc., and the collected liquid is introduced into the pathogen inspection device attached to the collection device, and the pathogen.
- FIG. 8 is a side view showing the collection device 10d according to the fifth embodiment.
- the collection device 10d according to the fifth embodiment will be described with reference to FIG.
- the side to which the introduction pipe 20d (described later) is connected is referred to as the lower side and the side to which the exhaust pipe 22d (described later) is connected is described as the upper side when viewed from the main body 18d (described later). (See the arrow in FIG. 8).
- the “downward" in FIG. 8 may be in the vertical direction.
- the collecting device 10d is a device that collects the exhaled object 1 in a liquid.
- the collection device 10d includes a container 12d, three rotating bodies 14, and a collection liquid 16.
- a container 12d includes a container 12d, three rotating bodies 14, and a collection liquid 16.
- the container 12d holds the collected liquid 16 in the container 12d.
- the container 12d supports three rotating bodies 14 so as to be rotatable around the rotation axes X1, X2, and X3 extending in the direction perpendicular to the vertical direction.
- the rotation axes X1, X2, and X3 extend in the same direction as each other and are arranged at intervals in the vertical direction.
- the rotation axes X1, X2, and X3 do not have to extend in the direction perpendicular to the vertical direction, and may extend in the direction intersecting the vertical direction.
- the container 12d has a main body 18d, an introduction pipe 20d, and an exhaust pipe 22d.
- the main body 18d is a portion that holds the collected liquid 16, and is a portion that rotatably supports the three rotating bodies 14 around the rotation axes X1, X2, and X3.
- the main body 18d has a substantially rectangular parallelepiped shape, and has a space D inside for accommodating the collecting liquid 16 and the three rotating bodies 14.
- the main body 18d has an inflow port 62 for allowing gas to flow into the collected liquid 16 from below the three rotating bodies 14.
- the inflow port 62 is provided at the lower part of the main body 18d.
- the inflow port 62 is configured like a check valve, for example, and allows gas to flow into the collection liquid 16 from the introduction pipe 20d, but does not allow the collection liquid 16 to flow into the introduction pipe 20d.
- the introduction pipe 20d is a part for introducing the exhaled breath of the user who uses the collection device 10d or the air around the collection device 10d into the collection liquid 16 from below the three rotating bodies 14. , Is connected to the inflow port 62 of the main body 18d.
- the exhaust pipe 22d is a part for discharging gas such as exhaled air introduced from the introduction pipe 20d, and is connected to the upper part of the main body 18d. The exhaust pipe 22d communicates with the space above the collected liquid 16 in the space D in the main body 18d.
- the three rotating bodies 14 are immersed in the collected liquid 16 in the container 12d, and are arranged side by side in the vertical direction.
- the top rotating body 14 is supported by the main body 18d so as to be rotatable around the rotating axis X1
- the middle rotating body 14 is supported by the main body 18d so as to be rotatable around the rotating axis X2.
- the bottom rotating body 14 is supported by the main body 18d so as to be rotatable around the rotation axis X3.
- Each of the three rotating bodies 14 includes first blade portions 44a to 44h, and each of the first blade portions 44a to 44h has a filter portion 46 (see FIGS.
- the filter unit 46 comes into contact with the gas 2 which has flowed into the collecting liquid 16 from the introduction pipe 20d (inflow port 62) and moves upward in the collecting liquid 16, so that the object 1 in the gas 2 is in contact with the gas 2. To capture. Although the details will be described later, the droplet 3 generated by the cooling unit 100d is introduced into the collection liquid 16 in a state of being contained in the exhaled air flowing through the introduction pipe 20d. The filter unit 46 (see FIGS. 1 to 3) comes into contact with the gas 2 which is the exhaled air introduced into the collecting liquid 16 from the introduction pipe 20d (inflow port 62) and moving upward in the collecting liquid 16. By doing so, the droplet 3 in the gas 2 is captured.
- the bottom rotating body 14 rotates around the rotation axis X3 when the gas 2 moving in the collected liquid 16 comes into contact with any of the first blade portions 44a to 44h of the bottom rotating body 14. do.
- the object 1 captured by the filter unit 46 included in the bottom rotating body 14 is collected in the collecting liquid 16.
- the droplets 3 captured by the filter unit 46 included in the bottom rotating body 14 are mixed with the collected liquid 16 and the droplets 3 are mixed.
- the object 1 contained in the above is collected in the collecting liquid 16.
- the gas 2 that has flowed into the collected liquid 16 is, for example, in the form of bubbles.
- the rotating body 14 in the middle rotates around the rotation axis X2 when the gas 2 moving in the collecting liquid 16 comes into contact with any of the first blade portions 44a to 44h of the rotating body 14 in the middle.
- the object 1 captured by the filter unit 46 included in the rotating body 14 in the middle is collected in the collecting liquid 16.
- the droplet 3 captured by the filter unit 46 included in the rotating body 14 in the middle is mixed with the collected liquid 16 and contained in the droplet 3.
- the object 1 is collected in the collecting liquid 16.
- the gas 2 that has flowed into the collected liquid 16 is, for example, in the form of bubbles.
- the top rotating body 14 rotates around the rotation axis X1 when the gas 2 moving in the collected liquid 16 comes into contact with any of the first blade portions 44a to 44h of the top rotating body 14. do.
- the object 1 captured by the filter unit 46 included in the top rotating body 14 is collected in the collecting liquid 16.
- the droplet 3 captured by the filter unit 46 included in the top rotating body 14 mixes with the collected liquid 16, and the droplet 3
- the object 1 contained in the above is collected in the collecting liquid 16.
- the gas 2 that has flowed into the collected liquid 16 is, for example, in the form of bubbles.
- the collecting liquid 16 is a liquid for collecting the object 1 and is filled inside the main body 18d. Specifically, the collected liquid 16 is filled inside the main body 18d so that the liquid surface 17 of the collected liquid 16 is formed above the top rotating body 14.
- the cooling unit 100d is a portion that drops the exhaled air into droplets by lowering the temperature of the exhaled air flowing through the introduction pipe 20d to generate the droplet 3 containing the object 1.
- the cooling unit 100d includes a housing 101d, a cooling source 102d, a power switch 103d, and a heat transfer rod 104d.
- the housing 101d is attached to the introduction pipe 20d, and the cooling source 102d is contained in the housing 101d.
- the cooling source 102d refer to the description of the cooling source 102 described above
- the power switch 103d refer to the description of the power switch 103 described above
- the heat transfer rod 104d refer to the description of the heat transfer rod 104 described above.
- the cooling unit 100d When the patient blows the exhaled breath, a part of the exhaled breath is cooled by the cooling unit 100d to become droplets 3, and is introduced into the collection liquid 16 together with the exhaled air flowing through the introduction tube 20d and not dropletized. .. As described above, the introduced droplet 3 is captured by the filter unit 46 of the rotating body 14 and mixed with the collected liquid 16, and the object 1 contained in the droplet 3 is captured in the collected liquid 16. Be gathered.
- rotating bodies 14 are installed in the main body 18d of the collecting device 10d, a plurality of rotating bodies 14 are installed in order to efficiently collect a small amount of pathogens. It is not necessary to install three rotating bodies 14.
- a phosphate buffer solution adjusted to a predetermined concentration may be injected into the main body 18d as a collecting solution 16.
- the phosphoric acid buffer solution may be injected in an amount in which all of the rotating body 14 installed in the main body 18d is immersed, and the connection point between the introduction pipe 20d and the main body 18d is the lowermost side surface or the bottom of the main body 18d. May be good.
- the gas entering from the introduction pipe 20d may be arranged so as to efficiently hit any of the first blade portions 44a to 44h included in each of the plurality of rotating bodies 14 installed inside the main body 18d.
- a plurality of rotating bodies 14 may be installed as shown in FIG.
- the inflow port 62 is installed at the lowermost part of the main body 18d that holds the collected liquid 16, so that the gas containing the pathogen comes into contact with the filter unit 46 of the rotating body 14 installed a plurality of times, and the pathogen is in the meantime. Is captured by the filter unit 46, and is separated and collected in the collected liquid 16 by the rotation of the rotating body 14.
- the pump 64 provided in the exhaust pipe 22d above the main body 18d, the gas can be efficiently introduced into the main body 18d from the introduction pipe 20d.
- the patient blows the exhaled air into the introduction tube 20d, and the filter unit 46 captures the object 1 such as a pathogen and the droplet 3 containing the object 1 and rotates.
- the object 1 such as a pathogen is separated and collected in the phosphate buffer solution.
- a pump 66 is installed in the introduction pipe 20d of the collection device 10d, and the pump 66 is installed. May be operated to allow gas to flow into the collected liquid 16.
- the phosphate buffer solution (collection solution 16) that has collected the object 1 such as a pathogen is collected and analyzed by a pathogen detection device. If the recovered phosphate buffer contains a pathogen, the pathogen can be collected by the pathogen detection device.
- the collecting device 10d is immersed in the main body 18d holding the collecting liquid 16 and the collecting liquid 16 in the main body 18d, and is a rotation axis extending in a direction intersecting the vertical direction.
- the introduction tube 20d for introducing the droplet 3 containing the object 1 and the first gas into the collected liquid 16 from below the rotating body 14, and the introduction tube 20d.
- the rotating body 14 includes one or a plurality of first blade portions projecting in a direction intersecting the rotation axis X1 with the cooling unit 100d for lowering the temperature of the generated gas and generating the droplet 3 and the first gas.
- each of the one or a plurality of first blade portions 44a to 44h has a filter portion 46.
- the droplet 3 containing the object 1 and the first gas are introduced into the collecting liquid 16 from below the rotating body 14, and the first gas with the droplet 3 moves upward.
- the filter unit 46 of the rotating body 14 captures the droplet 3 by coming into contact with the first gas accompanied by the droplet 3 moving upward.
- the rotating body 14 rotates around the rotation axis X3 when the first gas with the droplet 3 moving in the collected liquid 16 comes into contact with any of the first blade portions 44a to 44h.
- the droplet 3 captured by the filter unit 46 mixes with the collected liquid 16, and the object 1 contained in the droplet 3 is captured. It is collected in the liquid collection 16.
- the object 1 in the gas can be easily collected in the collection liquid 16.
- the first gas with the droplet 3 in the collected liquid 16 becomes a fine bubble by contacting the rotating body 14 rotating around the rotation axis X3, so that the droplet 3 is easily captured by the filter unit 46. Become.
- the object 1 in the gas can be collected more reliably.
- the collection device has been described above based on the embodiment, but the present disclosure is not limited to this embodiment. As long as it does not deviate from the gist of the present disclosure, one or more of the present embodiments may be modified by those skilled in the art, or may be constructed by combining components in different embodiments. It may be included within the scope of the embodiment.
- the cooling unit 100 cools the exhaled air flowing through the introduction pipe 20 to generate the droplet 3, and the cooling unit 100d cools the exhaled air flowing through the introduction pipe 20d to liquid.
- the cooling unit may cool the exhaled air in the main body of the container to generate droplets 3.
- the heat transfer rod is provided in the main body of the container so as not to hinder the rotation of the rotating body, and the cooling unit cools the exhaled air in the main body of the container by cooling the heat transfer rod. Then, the droplet 3 may be generated.
- the cooling unit 100 cools the exhaled air flowing in the introduction pipe 20 by cooling the heat transfer rod 104 located in the introduction pipe 20, and the cooling unit 100d is the introduction pipe.
- the cooling unit may cool the exhaled air in the container by cooling the container.
- the container has thermal conductivity
- cooling the outer surface of the container can lower the temperature of the inner surface of the container and lower the temperature of the exhaled air in the container.
- the container can be cooled by bringing a cooling source such as ice into contact with the outer surface of the container.
- the cylindrical portion 38 and the exhaust pipe 22 extend in the front-rear direction.
- the cylindrical portion 38 may extend upward and diagonally forward, or the exhaust pipe. 22 may extend diagonally upward and backward.
- the liquid level 17 of the collected liquid 16 is formed above the rotation axis X
- the present invention is not limited to this.
- the liquid level 17 of the collected liquid 16 may be formed below the rotation axis X.
- the collection device is provided with an oscillator so that the object 1 captured by the filter unit 46 can be peeled off from the filter unit 46 and easily collected by the collection liquid 16. May be good.
- the oscillator is, for example, an ultrasonic oscillator, which is electrically connected to a power source, and when the power switch is turned on, the oscillator vibrates and ultrasonic waves are oscillated.
- the oscillator is provided inside the container 12 and is immersed in the collected liquid 16 contained in the container 12. When the vibrator vibrates, the vibration of the vibrator is transmitted to the collecting liquid 16, and the collecting liquid 16 vibrates.
- a crystal oscillator, a SAW resonator, a MEMS oscillator, another piezoelectric oscillator, or the like can be used.
- This disclosure can be widely applied to devices that sample aerosols from the air.
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Abstract
Description
図1は、実施の形態1に係る捕集器具10を示す斜視図である。図2は、図1のII-II線断面図である。図3は、図1のIII-III線断面図である。図1から図3を参照して、実施の形態1に係る捕集器具10について説明する。なお、図1においては、図面が煩雑になることを避けるため、捕集液16(後述)の図示を省略する。図3においては、図面が煩雑になることを避けるため、第1羽根部44b、44d(後述)の図示を省略する。この実施の形態では、本体18(後述)の周壁部24(後述)から見て、導入管20(後述)側を前方とし、排気管22(後述)側を後方として説明する(図1および図2の矢印参照)。この実施の形態では、周壁部24から見て、左壁部26(後述)側を左方とし、右壁部28(後述)側を右方として説明する(図1および図3の矢印参照)。この実施の形態では、軸体42(後述)から見て、流路A側を上方とし、流路Aとは反対側を下方として説明する(図1~図3の矢印参照)。前後方向、左右方向、および上下方向は、相互に垂直に交わっている。
次に、実施の形態2について説明する。実施の形態2では、第1羽根部50a~50hのそれぞれの端部が容器12aの内面と接触した状態で、回転体14aが回転軸線X周りに回転する点において、実施の形態1と主に異なっている。
次に、実施の形態3について説明する。実施の形態3では、第1羽根部44a、44c、44e、44gに代えて、第2羽根部52a、52c、52e、52gを有している点において、実施の形態1と主に異なっている。
次に、実施の形態4について説明する。実施の形態4では、駆動装置54をさらに備えている点において、実施の形態1と主に異なっている。
次に、実施の形態5について説明する。
12、12a、12d 容器
14、14a、14b、14c 回転体
16 捕集液
17 液面
18、18a、18d 本体
20、20d 導入管
22、22d 排気管
24、24a 周壁部
26、26a 左壁部
28、28a 右壁部
30、32、34、36 穴部
38 円筒部
40 円錐筒部
42、42c 軸体
44a、44b、44c、44d、44e、44f、44g、44h、50a、50b、50c、50d、50e、50f、50g、50h 第1羽根部
46 フィルタ部
48、48a 枠部
51 接触部
52a、52c、52e、52g 第2羽根部
54 駆動装置
56 モータ
58 ベルト
60 回転軸
62 流入口
64、66 ポンプ
100、100d 冷却部
101、101d 筐体
102、102d 冷却源
103、103d 電源スイッチ
104、104d 伝熱棒
Claims (7)
- 対象物を含む呼気が導入される容器と、
前記容器内に導入された前記呼気の温度を低下させ、前記対象物を含む液滴を生成する冷却部と、
前記容器内に設けられて回転する回転体とを備え、
前記回転体は、前記回転体の回転軸線と交差する方向に突出する第1羽根部を有し、
前記第1羽根部は、前記液滴を捕捉するフィルタ部および前記液滴が透過しない板面部の少なくとも一方を有する、
捕集器具。 - 前記容器は、前記回転体を収容する空間を内部に有する本体と、前記本体に接続されかつ前記本体内の前記空間と連通する導入管とを有し、
前記冷却部は、前記導入管を流れる前記呼気を冷却する、
請求項1に記載の捕集器具。 - 前記容器は、捕集液を保持し、
前記少なくとも一方は、前記回転体が回転することによって、前記捕集液に浸漬されない位置から前記捕集液に浸漬される位置に移動する、
請求項1または2に記載の捕集器具。 - 前記回転体は、前記第1羽根部の端部が前記容器の内面に接した状態で、前記回転軸線周りに回転する、
請求項1から3のいずれか1項に記載の捕集器具。 - 前記第1羽根部は、前記フィルタ部を有し、
前記回転体は、前記回転軸線と交差する方向に突出しかつ前記フィルタ部よりも前記呼気を透過しにくい第2羽根部をさらに有する、
請求項1から4のいずれか1項に記載の捕集器具。 - 前記回転体を前記回転軸線周りに回転させる駆動装置をさらに備える、
請求項1から5のいずれか1項に記載の捕集器具。 - 捕集液を保持する本体と、
前記本体内の前記捕集液に浸漬され、上下方向と交差する方向に延びる回転軸線周りに回転する回転体と、
前記回転体よりも下方から前記捕集液中に対象物を含む液滴と第1気体を導入させるための導入管と、
前記導入管に導入された気体の温度を低下させ、前記液滴と前記第1気体を生成する冷却部とを備え、
前記回転体は、前記回転軸線と交差する方向に突出する第1羽根部を有し、
前記第1羽根部は、フィルタ部を有し、
前記液滴と前記第1気体が前記導入管から前記捕集液中に導入された後、前記フィルタ部は前記捕集液中を上方に向かって移動する前記液滴を伴うに接触し、前記フィルタ部は前記液滴を捕捉する、
捕集器具。
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EP21826572.6A EP4166921A4 (en) | 2020-06-16 | 2021-05-21 | COLLECTION DEVICE |
BR112022023246A BR112022023246A2 (pt) | 2020-06-16 | 2021-05-21 | Dispositivo de coletagem |
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