WO2020204574A1 - Bidirectional flow control valve and brain disease treatment system comprising same - Google Patents

Bidirectional flow control valve and brain disease treatment system comprising same Download PDF

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Publication number
WO2020204574A1
WO2020204574A1 PCT/KR2020/004405 KR2020004405W WO2020204574A1 WO 2020204574 A1 WO2020204574 A1 WO 2020204574A1 KR 2020004405 W KR2020004405 W KR 2020004405W WO 2020204574 A1 WO2020204574 A1 WO 2020204574A1
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WO
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Prior art keywords
flow
flow control
control body
flow path
fluid
Prior art date
Application number
PCT/KR2020/004405
Other languages
French (fr)
Korean (ko)
Inventor
유헌
김광기
정태신
Original Assignee
국립암센터
가천대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from KR1020190038033A external-priority patent/KR102201288B1/en
Priority claimed from KR1020190038034A external-priority patent/KR102151207B1/en
Application filed by 국립암센터, 가천대학교 산학협력단 filed Critical 국립암센터
Publication of WO2020204574A1 publication Critical patent/WO2020204574A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/32—Details
    • F16K1/34—Cutting-off parts, e.g. valve members, seats
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/02—Check valves with guided rigid valve members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/02—Check valves with guided rigid valve members
    • F16K15/06—Check valves with guided rigid valve members with guided stems
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/18—Check valves with actuating mechanism; Combined check valves and actuated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K27/00—Construction of housing; Use of materials therefor
    • F16K27/02—Construction of housing; Use of materials therefor of lift valves

Definitions

  • the present invention relates to a two-way flow control valve and a brain disease treatment system including the same.
  • Ventricular premature ejaculation is a procedure to treat hydrocephalus, etc., and monitors the brain pressure (ICP) and drains the cerebrospinal fluid (CSF) based on this. If drainage is temporary, external ventricular drain (EVD) is performed, and in the long-term, ventricular-abdominal shunt is performed.
  • ICP brain pressure
  • CSF cerebrospinal fluid
  • a two-way flow control valve is required to implement a new brain disease system.
  • the conventional bidirectional flow control valve is manufactured by combining a plurality of valves, there is a problem that a plurality of flow paths are required and the size is increased.
  • An object of the present invention is to provide a two-way flow control valve and a brain disease treatment system comprising the same.
  • the two-way flow control valve according to the present invention is small in size and has a simple structure, and the brain disease treatment system according to the present invention enables long-term drainage and both drug administration and cerebrospinal fluid drainage.
  • An object of the present invention is a two-way flow control valve, comprising: a valve body forming a flow path through which fluid moves; And a flow control unit positioned in the valve body, wherein the flow control unit includes: a first flow control unit and a second flow control unit that are movable in a flow path direction and face each other; A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller; And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body, and in a state in which the first flow control body and the second flow control body are in close contact, the first flow control A part of the sieve directly contacts the fluid flow in the direction of the first flow path from the second flow control body toward the first flow control body, and a part of the second flow control body is the second flow path direction opposite to the first direction. It is achieved by direct contact with the fluid flow of.
  • the first flow control body and the second flow control body contact each other to close the flow path, and when a fluid flow of a certain level or higher occurs in the flow path, the first flow control body and the second flow control body are spaced apart from each other.
  • the flow path can be opened.
  • the first pressing member and the second pressing member are made of elastic bodies having elastic force, and when a fluid flow of a certain level or more occurs in the direction of the first flow path, the first pressing member is deformed and the first flow control body When moving in the direction of the first passage to open the passage, and when a fluid flow of a certain level or more occurs in the direction of the second passage, the second pressure member is deformed and the second flow controller moves in the direction of the second passage.
  • the flow path can be opened.
  • the flow control unit further includes a stopper positioned between the first flow control body and the second flow control body, wherein the stopper restricts movement of the first flow control body in the direction of the second flow path, and , It is possible to limit the movement of the second flow controller in the direction of the first flow passage.
  • the flow control unit further includes a support unit for restricting movement of the pressing member, and the support unit includes: a first support unit for restricting movement of the first pressing member in the direction of the first flow path; It may include a second support for limiting the movement of the second pressing member in the direction of the second flow path.
  • the first flow control body has a first through hole for exposing the second flow control body to the fluid flow in the direction of the second flow path, and the second flow control body does not communicate with the first through hole and does not communicate with the first through hole.
  • a second through hole for exposing the first flow controller to the fluid flow in the direction of the first passage may be formed.
  • Another object of the present invention is to provide a brain disease treatment system, comprising: an internal device implanted into the skull of a patient and including a two-way flow control valve; And an extracorporeal device positioned outside the patient's skull and supplying drugs to the intracorporeal device or discharging cerebrospinal fluid from the intracorporeal device, wherein the extracorporeal device includes: a drug injection unit including a pump; Drainage container for storing cerebrospinal fluid discharged from the body; A connection part connecting the internal device to the drug injection part and the drainage container; And a control unit for controlling the operation of the connection unit.
  • the bidirectional flow control valve includes: a valve body defining a flow path through which fluid moves; And a flow control unit positioned in the valve body, wherein the flow control unit includes: a first flow control unit and a second flow control unit that are movable in a flow path direction and face each other; A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller; And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body, and in a state in which the first flow control body and the second flow control body are in close contact, the first flow control A part of the sieve directly contacts the fluid flow in the direction of the first flow path from the second flow control body toward the first flow control body, and a part of the second flow control body is the second flow path direction opposite to the first direction. Can be in direct contact with the fluid flow of
  • the connection unit may include a fluid line connecting the internal device, the drug injection unit, and the drainage container; And a flow path changer positioned on the fluid line and selectively connecting the internal device to the drug injection unit and the drainage container, and the controller may control the operation of the flow path changer.
  • the connection unit may include a flow meter measuring the flow rate of the fluid line; And a pressure gauge for measuring the pressure of the fluid line, and the controller may control the operation of the flow path converter based on a measurement result of the flowmeter and the pressure gauge.
  • the control unit calculates the brain pressure from the measurement result of the flow meter and the pressure gauge, and when the calculated brain pressure exceeds a certain value, the internal device is connected to the drainage container to control the operation of the flow path switch so that cerebrospinal fluid is discharged.
  • the drainage bag may be pressurized at a certain pressure.
  • the first flow control body and the second flow control body contact each other to close the flow path, and when a fluid flow of a certain level or higher occurs in the flow path, the first flow control body and the second flow control body are spaced apart from each other.
  • the flow path can be opened.
  • the first pressing member and the second pressing member are made of elastic bodies having elastic force, and when a fluid flow of a certain level or more occurs in the direction of the first flow path, the first pressing member is deformed and the first flow control body When moving in the direction of the first passage to open the passage, and when a fluid flow of a certain level or more occurs in the direction of the second passage, the second pressure member is deformed and the second flow controller moves in the direction of the second passage.
  • the flow path can be opened.
  • the flow control unit further includes a stopper positioned between the first flow control body and the second flow control body, wherein the stopper restricts movement of the first flow control body in the direction of the second flow path, and , It is possible to limit the movement of the second flow controller in the direction of the first flow passage.
  • the flow control unit further includes a support unit for restricting movement of the pressing member, and the support unit includes: a first support unit for restricting movement of the first pressing member in the direction of the first flow path; It may include a second support for limiting the movement of the second pressing member in the direction of the second flow path.
  • the first flow control body has a first through hole for exposing the second flow control body to the fluid flow in the direction of the second flow path, and the second flow control body does not communicate with the first through hole and does not communicate with the first through hole.
  • a second through hole for exposing the first flow controller to the fluid flow in the direction of the first passage may be formed.
  • a two-way flow control valve having a small size and a simple structure, and a brain disease treatment system according to the present invention can provide long-term drainage and a brain disease treatment system capable of both drug administration and cerebrospinal fluid drainage. .
  • FIG. 1 is a schematic diagram of a brain disease treatment system according to an embodiment of the present invention
  • FIG. 2 is a control diagram of a brain disease treatment system according to an embodiment of the present invention
  • FIG. 3 is a cut-away view of a two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention
  • FIG. 4 is an exploded view of a two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention
  • FIG. 5 is an enlarged view of a flow controller in a two-way flow control valve in a brain disease treatment system according to an embodiment of the present invention
  • FIG. 6 shows a modified example of the flow control body in the bidirectional flow control valve in the brain disease treatment system according to an embodiment of the present invention
  • FIG. 7 shows the operation of the flow control unit in the two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention
  • FIG 8 shows an example of a modified use of the brain disease treatment system according to an embodiment of the present invention.
  • the two-way flow control valve is intended to be used in an internal device, but the two-way flow control valve of the present invention can be used in other industrial and medical fields. That is, the bidirectional flow control valve of the present invention can be applied and used in facilities requiring bidirectional flow control operating in both directions.
  • FIGS. 1 and 2 A brain disease treatment system according to an embodiment of the present invention will be described with reference to FIGS. 1 and 2.
  • the brain disease treatment system 1 includes an internal device 10 located in the skull of a patient and an extracorporeal device 20 located outside the skull of the patient.
  • the internal device 10 is also called a chemopot (or brain port), and is implanted in the patient's head to inject drugs.
  • the internal device 10 according to the present invention includes a two-way flow control valve 11 shown in FIG. 3, and when the brain pressure exceeds a certain pressure by the two-way flow control valve 11, the cerebrospinal fluid is drained to the external device 20. , During administration, the drug flows from the extracorporeal device 20 to the ventricle. Details of the bidirectional flow control valve 11 will be described later.
  • the external device 20 includes a drainage container 210, a drug injection unit 220, a connection unit 230, and a control unit 240.
  • the drainage container 210 is also called a drainage bag, and accommodates cerebrospinal fluid to be drained. Since the drainage container 210 has a constant pressure, it is possible to change or control the brain pressure when the bidirectional flow control valve 11 is opened toward the extracorporeal device 20. This is the use of the sum of the cracking pressure (a fixed value determined by the mechanical characteristics of the valve) and the internal pressure of the drain container 210 when the bidirectional flow control valve 11 is opened. Pressure control of the drain container 210 may be performed in a conventional manner.
  • the drug injection unit 220 includes a drug storage unit 221 and a drug pump 222.
  • the drug storage unit 221 may be made of plastic, vinyl and/or metal, and the drug pump 222 allows the drug to be supplied to the ventricle at a constant flow rate.
  • the connection part 230 includes a fluid line 231, a pressure gauge 232, a flow meter 233, and a flow path converter 234.
  • the pressure gauge 232 (pressure sensor) measures the pressure of the fluid line 231, that is, the pressure of the input terminal of the internal device 10.
  • the pressure gauge 232 measures pressure at all times or at regular time intervals, and may measure pressure at irregular intervals or at a separate user request. The measured pressure value is used to convert brain pressure during administration.
  • the flow meter 233 measures the flow rate input to the internal device 10 at the time of administration, and the measured flow rate value is used to convert the brain pressure at the time of administration.
  • the flow path changer 234 performs a function of changing the connection state of the flow path by an electric signal or the like, and may use a solenoid valve.
  • the flow path converter 234 connects the internal device 10 to the drug injection unit 220 when administering, and connects the internal device 10 to the drain container 210 when draining.
  • the control unit 240 receives measured values from the pressure gauge 232 and the flow meter 233 and controls the flow path converter 234 and the drug injection unit 220 based on this. In addition to this, the control unit 240 may perform control by receiving an external instruction from a patient or medical staff. External instructions can be received via wired or wireless.
  • the pressure (brain pressure) in the ventricle and the pressure, flow rate, etc. at the input end of the internal device 10 have a certain functional relationship due to the mechanical properties of the two-way control valve 11 located in the internal device 10.
  • the control unit 240 converts the brain pressure using a functional relationship from the pressure value and the flow rate value measured at the time of administration. When the brain pressure exceeds a certain value, the controller 240 controls the flow path converter 234 to change and drain the flow path.
  • the power supply unit may use an external power source or use a battery.
  • FIG. 3 is a cutaway view of a bidirectional flow control valve according to an embodiment of the present invention
  • FIG. 4 is an exploded view of a bidirectional flow control valve according to an embodiment of the present invention
  • FIG. This is an enlarged view of the flow control body of the bidirectional flow control valve.
  • the bidirectional flow control valve 11 includes a valve body 1100 and a flow control unit 1200, and the flow control unit 1200 includes a first flow control body 1210 and a second flow control. It includes a sieve 1220, a first pressing member 1230, a second pressing member 1240, a stopper 1250, and supporting portions 1262 and 1264.
  • valve body 1100 forms a flow path through which fluid can move, and the direction of the flow path can be divided into a first flow path direction and a second flow path direction according to the fluid flow. .
  • the fluid flow flowing from the second flow control body 1220 to the first flow control body 1210 is in the direction of the first flow path, and conversely, from the first flow control body 1210 to the second flow control body 1220
  • the directed fluid flow is defined as the second flow path direction.
  • the valve body 1100 has a circular cross section, but may have a trapezoidal or rectangular shape in other embodiments. In this case, the shape of the flow control unit 1200 may also be changed.
  • the flow control unit 1200 is configured to control bidirectional flow control in the valve body 1100, and the flow control unit 1200 is driven to determine the closing, opening and opening directions of the flow path in the valve body 1100. This is done.
  • the operation of the flow control unit 1200 will be described in detail in the operation of the flow control unit of the bidirectional flow control valve according to an embodiment of the present invention in FIG. 7.
  • the first flow control body 1210 and the second flow control body 1220 are movable in the flow path direction within the valve body 1100 and face each other.
  • the outer circumferential surfaces of the first flow control body 1210 and the second flow control body 1220 may be in close contact with the inner circumferential surface so as not to allow fluid flow of the valve body 1100.
  • a first through hole 1212 is formed in the first flow control body 1210 to expose the second flow control body 1220. In a state in which both flow control bodies 1210 and 1220 are in close contact with each other through the first through hole 1212, the fluid flow moving in the direction of the second flow path and a part of the second flow control body 1220 directly contact each other.
  • the second flow control body 1220 has a second through hole 1222 that does not communicate with the first through hole 1212. In a state in which both flow control bodies 1210 and 1220 are in close contact with each other through the second through hole 1222, the fluid flow moving in the direction of the first flow path and a part of the first flow control body 1210 directly contact each other.
  • one through hole is formed in the center of the first flow control body 1210 and a plurality of through holes are formed around the second flow control body 1220, but in other embodiments, the size, shape, location, and The number can be varied in various ways.
  • the first flow control body 1210 and the second flow control body 1220 contact each other when no fluid flow occurs in the valve body 1100 to close the flow path, and when a fluid flow above a certain level occurs in the flow path, The first flow control body 1210 and the second flow control body 1220 are spaced apart from each other to open the flow path.
  • the first pressing member 1230 provides a pressing force to the first flow control body 1210 in the direction of the second flow control body 1220
  • the second pressing member 1240 Is to provide a pressing force to the second flow control body 1220 in the direction of the first flow control body 1210.
  • the first pressing member 1230 and the second pressing member 1240 are made of a spring, and in another embodiment, a configuration capable of providing pressing force, for example, rubber, may be used.
  • the stopper 1250 is coupled to the valve body 1100, is located between the first flow control body 1210 and the second flow control body 1220, the first flow control body ( 1210) and the second flow control body 1220 are in close contact with the first flow control body 1210 and the second flow control body 1220.
  • a part of the stopper 1250 is movable within the valve body 1100, or the stopper 1250 does not contact the flow control bodies 1210 and 1220 in a close contact with the flow control bodies 1210 and 1220. May not.
  • the stopper 1250 is connected to the first flow control body 1210 and the second flow control body 1220.
  • the sealing state may be improved in a close contact state by contacting the flow control bodies 1210 and 1220 and the stopper 1250.
  • the stopper 1250 limits the movement of the first flow control body 1210 in the direction of the second flow path, and restricts the movement of the second flow control body 1220 in the direction of the first flow path.
  • the stopper 1250 may have any shape as long as the movement of the first flow control body 1210 and the second flow control body 1220 is limited without significantly interfering with the flow of fluid in both directions in the valve body 1100. It is possible.
  • the stopper 1250 is coupled to the valve body 1100 and does not move in any direction within the valve body 1100, but in another embodiment, according to the fluid flow in the valve body 1100 It may be possible to move slightly.
  • the support portions 1262 and 1264 serve to support the first pressing member 1230 and the second pressing member 1240 from being separated from the inside of the valve body 1100, and the first flow path of the first pressing member 1230 A first support portion 1262 restricting movement in the direction and a second support portion 1264 restricting movement of the second pressing member 1240 in the direction of the second passage.
  • the first support portion 1262 and the second support portion 1264 are fixed to the valve body 1100.
  • the first pressing member 1230 is located between the first support portion 1262 and the first flow control body 1210, and the second pressing member 1240 includes a second support portion 1264 and a second flow control body 1220. ).
  • the support portions 1262 and 1264 are formed in a form in which three bars are overlapped, but in other embodiments, they may be provided in various forms such as a grid and a cross.
  • the support portions 1262 and 1264 are configured to limit movement of the first pressurizing member 1230 and the second pressurizing member 1240 in the valve body 1100 according to a bidirectional fluid flow, and the first support 1262 is a first It is in contact with the pressing member 1230, and the second support part 1264 is in contact with the second pressing member 1240.
  • One of the flow control bodies 1210 and 1220 may be made of a relatively soft material and the other may be made of a hard material in order to improve the sealing force in the close contact state.
  • a buffer member (not shown) for preventing the flow control bodies 1210 and 1220 made of hard material from being damaged by the pressing members 1230 and 1240 may be further included.
  • the buffer member (though not shown) may be located between the first pressing member 1230 and the first flow control body 1210, and between the second pressing member 1240 and the second flow control body 1220 You may.
  • the buffer member (although not shown) is made of a material that serves as a buffer between the flow control body and the pressure member made of a hard material, and for example, rubber such as silicone rubber may be used.
  • the shapes of the flow control bodies 1210 and 1220 may be variously modified, which will be described with reference to FIG. 6.
  • FIG. 6 shows a modified example of the flow control body in the bidirectional flow control valve according to an embodiment of the present invention.
  • the first flow control body 1210 has a disk shape and the second flow control body 1220 has a spherical shape.
  • the shapes of the first flow control body 1210 and the second flow control body 1220 may be variously changed.
  • FIG. 7 illustrates the operation of a flow control unit of a bidirectional flow control valve according to an embodiment of the present invention.
  • the first flow control body 1210 and the second flow control body 1220 does not generate a fluid flow in the valve body 1100 or a fluid flow (fluid pressure) below a certain level occurs.
  • the flow path is closed by contacting each other, and when a fluid flow (fluid pressure) above a certain level occurs in the flow path, the first flow control body 1210 and the second flow control body 1220 are spaced apart from each other to open the flow path. .
  • the flow control bodies 1210 and 1220 of the flow control unit 1200 and the pressure members 1230 and 1240 remain in a state where there is no movement inside the valve body 1100.
  • first flow control body 1210 and the second flow control body 1220 have the stopper 1250 in the center by the pressing members 1230 and 1240 applying a pressing force, and are in close contact with each other. This close contact state is maintained only when a fluid flow (fluid pressure) such that the pressure members 1230 and 1240 cannot be deformed occurs.
  • the first pressurizing member 1230 that provided the pressing force to the first flow controller 1210 in the direction of the second flow controller 1220 is reduced and deformed, so that the first flow controller 1210 moves in the direction of the first flow path. It moves and is spaced apart from the second flow control body 1220 to open the flow path through both through holes 1212 and 1222.
  • the movement of the first pressing member 1230 is restricted by the first support portion 1262, and the movement of the second flow control body 1220 is restricted by the stopper.
  • the second pressurizing member 1230 that provided the pressing force to the second flow controller 1220 in the direction of the first flow controller 1210 is deformed, and the second flow controller 1220 moves in the direction of the second flow path.
  • the flow path through both through holes 1212 and 1222 is opened.
  • the movement of the second pressing member 1240 is restricted by the second support portion 1264, and the movement of the first flow control body 1210 is restricted by the stopper.
  • the first flow control body 1210 and the second flow control body 1220 which were limited in motion by the pressing members 1262 and 1264, are pressurized members according to different fluid flows (bidirectional fluid flows).
  • the flow path in the valve body 1100 is opened by moving in the direction of the first flow passage or the direction of the second flow passage.
  • the flow path opening pressure (flow path) is made possible by adjusting the elasticity of the pressing members 1230 and 1240 and the area and shape of the through holes 1212 and 1222 formed in the flow control bodies 1210 and 1220.
  • the two-way flow control valve according to the present invention enables two-way flow control only by using a single valve, and the effect of miniaturization and simplification occurs due to the use of a single valve.
  • the controller 240 controls the flow path switch 234 to connect the internal device 10 and the drug injection unit 220 to inject the drug.
  • the two-way control valve 11 forms a flow path in the direction of the second flow path (ventricular direction) by the pressure caused by the drug injection, so that the drug is injected into the ventricle.
  • the controller 240 controls the flow path switch 234 to connect the internal device 10 and the drainage container 210.
  • the bidirectional control valve 11 forms a flow path in the direction of the first flow path (outside) by the brain pressure, so that the cerebrospinal fluid is discharged into the drainage container 210.
  • administration and long-term drainage are possible by using the internal device 10 having an allowable pressure in both directions and the drainage container 210 capable of adjusting the internal pressure.
  • a modified use example of the brain disease treatment system according to an embodiment of the present invention will be described with reference to FIG. 8.
  • the present invention provides a method for treating brain diseases as described above.

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Abstract

The present invention relates to a bidirectional flow control valve and a brain disease treatment system comprising same. The bidirectional flow control valve comprises a first flow control body and a second flow control body which are in close contact with each other, wherein a part of the first flow control body directly comes into contact with fluid flow in a first fluid channel direction oriented from the second flow control body toward the first flow control body, and a part of the second flow control body directly comes into contact with fluid flow in a second fluid channel direction opposite to the first direction.

Description

양방향 흐름제어 밸브 및 이를 포함하는 뇌질환치료 시스템Bidirectional flow control valve and brain disease treatment system including the same
본 발명은 양방향 흐름제어 밸브 및 이를 포함하는 뇌질환치료 시스템에 관한 것이다.The present invention relates to a two-way flow control valve and a brain disease treatment system including the same.
뇌실조루술은 뇌수종(hydrocephalus)등을 치료하기 위한 시술법으로서 뇌압(ICP)을 모니터하고 이를 기준으로 뇌척수액(CSF)을 배액(drainage)하도록 한다. 배액이 한시적일 경우에는 뇌실액배액술(external ventricular drain, EVD)을, 장기적인 경우에는 뇌실-복강간단락술(shunt)을 시술하게 된다.Ventricular premature ejaculation is a procedure to treat hydrocephalus, etc., and monitors the brain pressure (ICP) and drains the cerebrospinal fluid (CSF) based on this. If drainage is temporary, external ventricular drain (EVD) is performed, and in the long-term, ventricular-abdominal shunt is performed.
뇌실액배액술의 경우는 장기 배액이 어렵고 뇌실-복강간단락술은 시술이 상대적으로 복잡하고 약물의 투약이 어려운 단점이 있다.In the case of ventricular drainage, long-term drainage is difficult, and the ventricular-abdominal shunt procedure is relatively complicated and difficult to administer drugs.
또한 새로운 뇌질환시스템의 구현을 위해서는 양방향 흐름제어 밸브가 필요하다. 그러나 종래의 양방향 흐름제어 밸브는 복수의 밸브를 조합해서 제조했기 때문에 복수의 유로가 필요하고 크기가 커지는 문제가 있었다.In addition, a two-way flow control valve is required to implement a new brain disease system. However, since the conventional bidirectional flow control valve is manufactured by combining a plurality of valves, there is a problem that a plurality of flow paths are required and the size is increased.
본 발명의 목적은 양방향 흐름제어 밸브 및 이를 포함하는 뇌질환치료 시스템을 제공하는 것이다. 본 발명에 따른 양방향 흐름제어 밸브는 크기가 작고 구조가 간단하며, 본 발명에 따른 뇌질환 치료 시스템은 장기 배액이 가능하고 약물의 투약 및 뇌척수액 배액이 모두 가능하다. An object of the present invention is to provide a two-way flow control valve and a brain disease treatment system comprising the same. The two-way flow control valve according to the present invention is small in size and has a simple structure, and the brain disease treatment system according to the present invention enables long-term drainage and both drug administration and cerebrospinal fluid drainage.
상기 본 발명의 목적은 양방향 흐름제어 밸브에 있어서, 유체가 이동하는 유로를 형성하는 밸브 본체와; 상기 밸브 본체 내에 위치하는 흐름제어부를 포함하며, 상기 흐름제어부는, 유로 방향으로 이동가능하며 서로 마주하는 제1흐름제어체 및 제2흐름제어체; 상기 제1흐름제어체에 상기 제2흐름제어체 방향으로 가압력을 제공하는 제1가압부재; 상기 제2흐름제어체에 상기 제1흐름제어체 방향으로 가압력을 제공하는 제2가압부재를 포함하며, 상기 제1흐름제어체와 상기 제2흐름제어체가 밀착된 상태에서, 상기 제1흐름제어체의 일부는 제2흐름제어체에서 상기 제1흐름제어체를 향하는 제1유로 방향의 유체흐름에 직접 접촉하며, 상기 제2흐름제어체의 일부는 제1방향과 반대방향인 제2유로 방향의 유체흐름에 직접 접촉하는 것에 의해 달성된다.An object of the present invention is a two-way flow control valve, comprising: a valve body forming a flow path through which fluid moves; And a flow control unit positioned in the valve body, wherein the flow control unit includes: a first flow control unit and a second flow control unit that are movable in a flow path direction and face each other; A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller; And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body, and in a state in which the first flow control body and the second flow control body are in close contact, the first flow control A part of the sieve directly contacts the fluid flow in the direction of the first flow path from the second flow control body toward the first flow control body, and a part of the second flow control body is the second flow path direction opposite to the first direction. It is achieved by direct contact with the fluid flow of.
상기 제1흐름제어체와 상기 제2흐름제어체는 접촉하여 상기 유로를 폐쇄하며, 상기 유로에 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1흐름제어체 및 상기 제2흐름제어체가 서로 이격하여 상기 유로를 개방할 수 있다.The first flow control body and the second flow control body contact each other to close the flow path, and when a fluid flow of a certain level or higher occurs in the flow path, the first flow control body and the second flow control body are spaced apart from each other. The flow path can be opened.
상기 제1가압부재 및 제2가압부재는 탄성력을 가지고 있는 탄성체로 이루어져 있으며, 상기 제1유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1가압부재가 변형되면서 상기 제1흐름제어체가 상기 제1유로 방향으로 이동하여 상기 유로를 개방하고, 상기 제2유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제2가압부재가 변형되면서 상기 제2흐름제어체가 상기 제2유로 방향으로 이동하여 상기 유로를 개방할 수 있다.The first pressing member and the second pressing member are made of elastic bodies having elastic force, and when a fluid flow of a certain level or more occurs in the direction of the first flow path, the first pressing member is deformed and the first flow control body When moving in the direction of the first passage to open the passage, and when a fluid flow of a certain level or more occurs in the direction of the second passage, the second pressure member is deformed and the second flow controller moves in the direction of the second passage. The flow path can be opened.
상기 흐름제어부는, 상기 제1흐름제어체 및 상기 제2흐름제어체 사이에 위치하는 스토퍼를 더 포함하며, 상기 스토퍼는, 상기 제1흐름제어체의 상기 제2유로 방향으로의 이동을 제한하고, 상기 제2흐름제어체의 상기 제1유로 방향으로의 이동을 제한할 수 있다.The flow control unit further includes a stopper positioned between the first flow control body and the second flow control body, wherein the stopper restricts movement of the first flow control body in the direction of the second flow path, and , It is possible to limit the movement of the second flow controller in the direction of the first flow passage.
상기 흐름제어부는, 상기 가압부재의 이동을 제한하는 지지부를 더 포함하며, 상기 지지부는, 상기 제1가압부재의 상기 제1유로 방향으로의 이동을 제한하는 제1지지부; 상기 제2가압부재의 상기 제2유로 방향으로의 이동을 제한하는 제2지지부를 포함할 수 있다.The flow control unit further includes a support unit for restricting movement of the pressing member, and the support unit includes: a first support unit for restricting movement of the first pressing member in the direction of the first flow path; It may include a second support for limiting the movement of the second pressing member in the direction of the second flow path.
상기 제1흐름제어체에는 상기 제2흐름제어체를 상기 제2유로 방향의 유체흐름에 노출시키는 제1관통공이 형성되어 있으며, 상기 제2흐름제어체에는 상기 제1관통공과 연통하지 않으며 상기 제1흐름제어체를 상기 제1유로 방향의 유체흐름에 노출시키는 제2관통공이 형성되어 있을 수 있다.The first flow control body has a first through hole for exposing the second flow control body to the fluid flow in the direction of the second flow path, and the second flow control body does not communicate with the first through hole and does not communicate with the first through hole. A second through hole for exposing the first flow controller to the fluid flow in the direction of the first passage may be formed.
상기 본 발명의 다른 목적은 뇌질환치료 시스템에 있어서, 환자의 두개골 내에 이식되며, 양방향 흐름제어 밸브를 포함하는 체내장치; 및 환자의 두개골 외에 위치하며, 상기 체내장치에 약물을 공급하거나 상기 체내장치로부터 뇌척수액을 배출하는 체외장치를 포함하며, 상기 체외장치는, 펌프를 포함하는 약물투입부; 체외로 배출된 뇌척수액을 보관하는 배액용기; 상기 체내장치를 상기 약물투입부 및 상기 배액용기에 연결하는 연결부; 및 상기 연결부의 작동을 제어하는 제어부를 포함하는 것에 의해 달성된다.Another object of the present invention is to provide a brain disease treatment system, comprising: an internal device implanted into the skull of a patient and including a two-way flow control valve; And an extracorporeal device positioned outside the patient's skull and supplying drugs to the intracorporeal device or discharging cerebrospinal fluid from the intracorporeal device, wherein the extracorporeal device includes: a drug injection unit including a pump; Drainage container for storing cerebrospinal fluid discharged from the body; A connection part connecting the internal device to the drug injection part and the drainage container; And a control unit for controlling the operation of the connection unit.
상기 양방향 흐름제어 밸브는, 유체가 이동하는 유로를 형성하는 밸브 본체와; 상기 밸브 본체 내에 위치하는 흐름제어부를 포함하며, 상기 흐름제어부는, 유로 방향으로 이동가능하며 서로 마주하는 제1흐름제어체 및 제2흐름제어체; 상기 제1흐름제어체에 상기 제2흐름제어체 방향으로 가압력을 제공하는 제1가압부재; 상기 제2흐름제어체에 상기 제1흐름제어체 방향으로 가압력을 제공하는 제2가압부재를 포함하며, 상기 제1흐름제어체와 상기 제2흐름제어체가 밀착된 상태에서, 상기 제1흐름제어체의 일부는 제2흐름제어체에서 상기 제1흐름제어체를 향하는 제1유로 방향의 유체흐름에 직접 접촉하며, 상기 제2흐름제어체의 일부는 제1방향과 반대방향인 제2유로 방향의 유체흐름에 직접 접촉할 수 있다.The bidirectional flow control valve includes: a valve body defining a flow path through which fluid moves; And a flow control unit positioned in the valve body, wherein the flow control unit includes: a first flow control unit and a second flow control unit that are movable in a flow path direction and face each other; A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller; And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body, and in a state in which the first flow control body and the second flow control body are in close contact, the first flow control A part of the sieve directly contacts the fluid flow in the direction of the first flow path from the second flow control body toward the first flow control body, and a part of the second flow control body is the second flow path direction opposite to the first direction. Can be in direct contact with the fluid flow of
상기 연결부는, 상기 체내장치와 상기 약물투입부 및 상기 배액용기를 연결하는 유체라인; 및 상기 유체라인 상에 위치하며, 상기 체내장치를 상기 약물투입부 및 상기 배액용기에 선택적으로 연결하는 유로전환기를 포함하며, 상기 제어부는 상기 유로전환기의 작동을 제어할 수 있다.The connection unit may include a fluid line connecting the internal device, the drug injection unit, and the drainage container; And a flow path changer positioned on the fluid line and selectively connecting the internal device to the drug injection unit and the drainage container, and the controller may control the operation of the flow path changer.
상기 연결부는, 상기 유체라인의 유량을 측정하는 유량계; 및 상기 유체라인의 압력을 측정하는 압력계를 더 포함하며, 상기 제어부는 상기 유량계 및 상기 압력계의 측정결과를 기초로 상기 유로전환기의 작동을 제어할 수 있다.The connection unit may include a flow meter measuring the flow rate of the fluid line; And a pressure gauge for measuring the pressure of the fluid line, and the controller may control the operation of the flow path converter based on a measurement result of the flowmeter and the pressure gauge.
상기 제어부는 상기 유량계 및 상기 압력계의 측정결과로부터 뇌압을 계산하며, 계산된 뇌압이 일정한 값을 넘으면 상기 체내장치를 상기 배액용기에 연결되어 뇌척수액이 배출되도록 상기 유로전환기의 작동을 제어할 수 있다.The control unit calculates the brain pressure from the measurement result of the flow meter and the pressure gauge, and when the calculated brain pressure exceeds a certain value, the internal device is connected to the drainage container to control the operation of the flow path switch so that cerebrospinal fluid is discharged.
상기 배액백은 일정 압력으로 가압될 수 있다.The drainage bag may be pressurized at a certain pressure.
상기 제1흐름제어체와 상기 제2흐름제어체는 접촉하여 상기 유로를 폐쇄하며, 상기 유로에 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1흐름제어체 및 상기 제2흐름제어체가 서로 이격하여 상기 유로를 개방할 수 있다.The first flow control body and the second flow control body contact each other to close the flow path, and when a fluid flow of a certain level or higher occurs in the flow path, the first flow control body and the second flow control body are spaced apart from each other. The flow path can be opened.
상기 제1가압부재 및 제2가압부재는 탄성력을 가지고 있는 탄성체로 이루어져 있으며, 상기 제1유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1가압부재가 변형되면서 상기 제1흐름제어체가 상기 제1유로 방향으로 이동하여 상기 유로를 개방하고, 상기 제2유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제2가압부재가 변형되면서 상기 제2흐름제어체가 상기 제2유로 방향으로 이동하여 상기 유로를 개방할 수 있다.The first pressing member and the second pressing member are made of elastic bodies having elastic force, and when a fluid flow of a certain level or more occurs in the direction of the first flow path, the first pressing member is deformed and the first flow control body When moving in the direction of the first passage to open the passage, and when a fluid flow of a certain level or more occurs in the direction of the second passage, the second pressure member is deformed and the second flow controller moves in the direction of the second passage. The flow path can be opened.
상기 흐름제어부는, 상기 제1흐름제어체 및 상기 제2흐름제어체 사이에 위치하는 스토퍼를 더 포함하며, 상기 스토퍼는, 상기 제1흐름제어체의 상기 제2유로 방향으로의 이동을 제한하고, 상기 제2흐름제어체의 상기 제1유로 방향으로의 이동을 제한할 수 있다.The flow control unit further includes a stopper positioned between the first flow control body and the second flow control body, wherein the stopper restricts movement of the first flow control body in the direction of the second flow path, and , It is possible to limit the movement of the second flow controller in the direction of the first flow passage.
상기 흐름제어부는, 상기 가압부재의 이동을 제한하는 지지부를 더 포함하며, 상기 지지부는, 상기 제1가압부재의 상기 제1유로 방향으로의 이동을 제한하는 제1지지부; 상기 제2가압부재의 상기 제2유로 방향으로의 이동을 제한하는 제2지지부를 포함할 수 있다.The flow control unit further includes a support unit for restricting movement of the pressing member, and the support unit includes: a first support unit for restricting movement of the first pressing member in the direction of the first flow path; It may include a second support for limiting the movement of the second pressing member in the direction of the second flow path.
상기 제1흐름제어체에는 상기 제2흐름제어체를 상기 제2유로 방향의 유체흐름에 노출시키는 제1관통공이 형성되어 있으며, 상기 제2흐름제어체에는 상기 제1관통공과 연통하지 않으며 상기 제1흐름제어체를 상기 제1유로 방향의 유체흐름에 노출시키는 제2관통공이 형성되어 있을 수 있다.The first flow control body has a first through hole for exposing the second flow control body to the fluid flow in the direction of the second flow path, and the second flow control body does not communicate with the first through hole and does not communicate with the first through hole. A second through hole for exposing the first flow controller to the fluid flow in the direction of the first passage may be formed.
본 발명에 따르면 양방향 흐름제어 밸브는 크기가 작고 구조가 간단한 양방향 흐름제어 밸브와 본 발명에 따른 뇌질환 치료 시스템은 장기 배액이 가능하고 약물의 투약 및 뇌척수액 배액이 모두 가능한 뇌질환 치료 시스템이 제공된다.According to the present invention, a two-way flow control valve having a small size and a simple structure, and a brain disease treatment system according to the present invention can provide long-term drainage and a brain disease treatment system capable of both drug administration and cerebrospinal fluid drainage. .
도 1은 본 발명의 일실시예에 따른 뇌질환 치료 시스템의 개략도이고,1 is a schematic diagram of a brain disease treatment system according to an embodiment of the present invention,
도 2는 본 발명의 일실시예에 따른 뇌질환 치료 시스템의 제어도이고,2 is a control diagram of a brain disease treatment system according to an embodiment of the present invention,
도 3은 본 발명의 일실시예에 따른 뇌질환 치료 시스템에서 양방향 흐름제어 밸브의 절개도이고, 3 is a cut-away view of a two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention,
도 4는 본 발명의 일실시예에 따른 뇌질환 치료 시스템에서 양방향 흐름제어 밸브의 분해도이고,4 is an exploded view of a two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention,
도 5는 본 발명의 일실시예에 따른 뇌질환 치료 시스템에서 양방향 흐름제어 밸브에서 흐름제어체를 확대하여 나타낸 것이고, 5 is an enlarged view of a flow controller in a two-way flow control valve in a brain disease treatment system according to an embodiment of the present invention,
도 6은 본 발명의 일실시예에 따른 뇌질환 치료 시스템에서 양방향 흐름제어 밸브에서 흐름제어체의 변형예를 나타낸 것이고, 6 shows a modified example of the flow control body in the bidirectional flow control valve in the brain disease treatment system according to an embodiment of the present invention,
도 7은 본 발명의 일실시예에 따른 뇌질환 치료 시스템에서 양방향 흐름제어 밸브에서 흐름제어부의 동작을 나타낸 것이고,7 shows the operation of the flow control unit in the two-way flow control valve in the brain disease treatment system according to an embodiment of the present invention,
도 8은 본 발명의 일실시예에 따른 뇌질환 치료 시스템의 변형 사용예를 나타낸 것이다.8 shows an example of a modified use of the brain disease treatment system according to an embodiment of the present invention.
이하 첨부된 도면을 참조하여 본 발명의 실시예를 상세히 설명한다. 그러나 본 실시예는 이하에서 개시되는 실시예에 한정되는 것이 아니라 서로 다양한 형태로 구현될 수 있으며, 단지 본 실시예는 본 발명의 개시가 완전하도록 하며, 통상의 지식을 가진 자에게 발명의 범주를 완전하게 알려주기 위해 제공하는 것이다. 도면에서의 요소의 형상 등은 보다 명확한 설명을 위하여 과장되게 표현된 부분이 있을 수 있으며, 도면 상에서 동일 부호로 표시된 요소는 동일 요소를 의미한다. Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings. However, this embodiment is not limited to the embodiments disclosed below, but may be implemented in various forms, only this embodiment makes the disclosure of the present invention complete, and the scope of the invention is given to those of ordinary skill in the art. It is provided to be fully informed. The shapes of elements in the drawings may be exaggerated for a more clear explanation, and elements indicated by the same reference numerals in the drawings mean the same elements.
이하의 설명에서 양방향 흐름제어 밸브는 체내장치에 사용되는 것으로 되어 있으나, 본 발명의 양방향 흐름제어 밸브는 다른 산업용 및 의료용 분야에 사용될 수 있다. 즉, 본 발명의 양방향 흐름제어 밸브는 양방향 모두에서 동작하는 양방향 흐름제어가 필요한 설비에 적용되어 사용될 수 있다.In the following description, the two-way flow control valve is intended to be used in an internal device, but the two-way flow control valve of the present invention can be used in other industrial and medical fields. That is, the bidirectional flow control valve of the present invention can be applied and used in facilities requiring bidirectional flow control operating in both directions.
도 1 및 도 2를 참조하여 본 발명의 일실시예에 따른 뇌질환 치료 시스템에 관하여 설명한다. A brain disease treatment system according to an embodiment of the present invention will be described with reference to FIGS. 1 and 2.
본 발명의 일실시예에 따른 뇌질환 치료 시스템(1)은 환자의 두개골 내에 위치하는 체내장치(10) 및 환자의 두개골 외부에 위치하는 체외장치(20)를 포함한다.The brain disease treatment system 1 according to an embodiment of the present invention includes an internal device 10 located in the skull of a patient and an extracorporeal device 20 located outside the skull of the patient.
체내장치(10)는 케모포트(또는 브레인 포트)라고도 불리며, 약물을 주입할 수 있도록 환자의 머리 내에 이식된다. 본 발명에 따른 체내장치(10)는 도 3에 나타낸 양방향 흐름제어 밸브(11)를 포함하는데, 양방향 흐름제어 밸브(11)에 의해 뇌압이 일정한 압력을 넘으면 체외장치(20)로 뇌척수액을 배액하고, 투약 시에는 체외장치(20)로부터 뇌실로의 약물 흐름을 허용한다. 양방향 흐름제어 밸브(11)에 대한 자세한 내용은 후술한다.The internal device 10 is also called a chemopot (or brain port), and is implanted in the patient's head to inject drugs. The internal device 10 according to the present invention includes a two-way flow control valve 11 shown in FIG. 3, and when the brain pressure exceeds a certain pressure by the two-way flow control valve 11, the cerebrospinal fluid is drained to the external device 20. , During administration, the drug flows from the extracorporeal device 20 to the ventricle. Details of the bidirectional flow control valve 11 will be described later.
체외장치(20)는 배액용기(210), 약물투입부(220), 연결부(230) 및 제어부(240)를 포함한다.The external device 20 includes a drainage container 210, a drug injection unit 220, a connection unit 230, and a control unit 240.
배액용기(210)는 배액백이라고도 불리며, 배액되는 뇌척수액을 수용한다. 배액용기(210)는 일정한 압력을 가지고 있어서 양방향 흐름제어 밸브(11)가 체외장치(20) 방향으로 열릴 때의 뇌압을 변경 내지 조절할 수 있다. 이는 양방향 흐름제어밸브(11)가 열릴 때의 압력은 크래킹 압력(밸브의 기계적 특성에 의해 결정되는 고정 값)과 배액용기(210)의 내부 압력의 합임을 이용한 것이다. 배액용기(210)의 압력조절은 통상의 방법으로 수행될 수 있다.The drainage container 210 is also called a drainage bag, and accommodates cerebrospinal fluid to be drained. Since the drainage container 210 has a constant pressure, it is possible to change or control the brain pressure when the bidirectional flow control valve 11 is opened toward the extracorporeal device 20. This is the use of the sum of the cracking pressure (a fixed value determined by the mechanical characteristics of the valve) and the internal pressure of the drain container 210 when the bidirectional flow control valve 11 is opened. Pressure control of the drain container 210 may be performed in a conventional manner.
약물투입부(220)는 약물저장부(221)와 약물펌프(222)를 포함한다. 약물저장부(221)는 플라스틱, 비닐 및/또는 금속재질로 마련될 수 있으며, 약물펌프(222)는 뇌실에 약물이 일정한 유속으로 공급되도록 한다.The drug injection unit 220 includes a drug storage unit 221 and a drug pump 222. The drug storage unit 221 may be made of plastic, vinyl and/or metal, and the drug pump 222 allows the drug to be supplied to the ventricle at a constant flow rate.
연결부(230)는 유체라인(231), 압력계(232), 유량계(233) 및 유로전환기(234)를 포함한다.The connection part 230 includes a fluid line 231, a pressure gauge 232, a flow meter 233, and a flow path converter 234.
압력계(232, 압력센서)는 유체라인(231)의 압력, 즉 체내장치(10)의 입력단의 압력을 측정한다. 압력계(232)는 상시 또는 일정한 시간 간격으로 압력을 측정하며, 비정기적으로 또는 별도의 사용자 요청 등에 따라 압력을 측정할 수도 있다. 측정한 압력값은 투약 시에 뇌압을 환산하는데 사용된다.The pressure gauge 232 (pressure sensor) measures the pressure of the fluid line 231, that is, the pressure of the input terminal of the internal device 10. The pressure gauge 232 measures pressure at all times or at regular time intervals, and may measure pressure at irregular intervals or at a separate user request. The measured pressure value is used to convert brain pressure during administration.
유량계(233)는 투약 시에 체내장치(10)에 입력되는 유량을 측정하는 것으로, 측정된 유량값은 투약 시에 뇌압을 환산하는데 사용된다.The flow meter 233 measures the flow rate input to the internal device 10 at the time of administration, and the measured flow rate value is used to convert the brain pressure at the time of administration.
유로전환기(234)는 전기적 신호 등에 의해 유로의 연결상태를 바꾸는 기능을 수행하며, 솔레노이드 밸브를 이용할 수 있다. 유로전환기(234)는 투약 시에는 체내장치(10)를 약물투입부(220)에 연결하고 배액 시에는 체내장치(10)를 배액용기(210)에 연결한다.The flow path changer 234 performs a function of changing the connection state of the flow path by an electric signal or the like, and may use a solenoid valve. The flow path converter 234 connects the internal device 10 to the drug injection unit 220 when administering, and connects the internal device 10 to the drain container 210 when draining.
제어부(240)는 압력계(232) 및 유량계(233)로부터 측정값을 입력받고 이를 바탕으로 유로전환기(234) 및 약물투입부(220)를 제어한다. 제어부(240)는 이 외에도 환자나 의료진 등으로부터의 외부지시를 받아 제어를 실시할 수 있다. 외부지시는 유선 또는 무선을 통해 받을 수 있다.The control unit 240 receives measured values from the pressure gauge 232 and the flow meter 233 and controls the flow path converter 234 and the drug injection unit 220 based on this. In addition to this, the control unit 240 may perform control by receiving an external instruction from a patient or medical staff. External instructions can be received via wired or wireless.
뇌실 내의 압력(뇌압)과 체내장치(10)의 입력단의 압력, 유량 등은 체내장치(10) 내에 위치하는 양방향제어밸브(11)의 기계적 특성에 의해 일정한 함수관계를 가진다. 제어부(240)는 투약 시에 측정된 압력값 및 유량값으로부터 함수관계를 이용해 뇌압을 환산한다. 제어부(240)는 뇌압이 일정한 값을 넘으면 유로를 변경시켜 배액되도록 유로전환기(234)를 제어한다.The pressure (brain pressure) in the ventricle and the pressure, flow rate, etc. at the input end of the internal device 10 have a certain functional relationship due to the mechanical properties of the two-way control valve 11 located in the internal device 10. The control unit 240 converts the brain pressure using a functional relationship from the pressure value and the flow rate value measured at the time of administration. When the brain pressure exceeds a certain value, the controller 240 controls the flow path converter 234 to change and drain the flow path.
이상의 도면 및 설명에서는 전원공급을 위한 전원부가 생략되었다. 전원부는 외부 전원을 이용하거나 배터리를 이용할 수 있다.In the above drawings and description, a power supply for power supply is omitted. The power supply unit may use an external power source or use a battery.
이하 도 3 내지 도 5를 참조하여 본 발명에서의 양방향 흐름제어 밸브에 대하여 설명한다.Hereinafter, a bidirectional flow control valve in the present invention will be described with reference to FIGS. 3 to 5.
도 3은 본 발명의 일실시예에 따른 양방향 흐름제어 밸브의 절개도이고, 도 4는 본 발명의 일실시예에 따른 양방향 흐름제어 밸브의 분해도이고, 도 5는 본 발명의 일실시예에 따른 양방향 흐름제어 밸브 흐름제어체를 확대하여 나타낸 것이다. 3 is a cutaway view of a bidirectional flow control valve according to an embodiment of the present invention, FIG. 4 is an exploded view of a bidirectional flow control valve according to an embodiment of the present invention, and FIG. This is an enlarged view of the flow control body of the bidirectional flow control valve.
도 3에 도시된 바와 같이, 양방향 흐름제어 밸브(11)는 밸브 본체(1100) 및 흐름제어부(1200)를 포함하며, 흐름제어부(1200)는 제1흐름제어체(1210), 제2흐름제어체(1220), 제1가압부재(1230), 제2가압부재(1240), 스토퍼(1250), 지지부(1262, 1264)를 포함한다. As shown in FIG. 3, the bidirectional flow control valve 11 includes a valve body 1100 and a flow control unit 1200, and the flow control unit 1200 includes a first flow control body 1210 and a second flow control. It includes a sieve 1220, a first pressing member 1230, a second pressing member 1240, a stopper 1250, and supporting portions 1262 and 1264.
도 3 및 도 4에 도시된 바와 같이, 밸브 본체(1100)는 내부에 유체 이동이 가능한 유로를 형성하고 있으며, 유로의 방향은 유체흐름에 따라 제1유로 방향 및 제2유로 방향으로 나눌 수 있다.As shown in FIGS. 3 and 4, the valve body 1100 forms a flow path through which fluid can move, and the direction of the flow path can be divided into a first flow path direction and a second flow path direction according to the fluid flow. .
본 발명에서는 제2흐름제어체(1220)에서 제1흐름제어체(1210)로 흐르는 유체 흐름이 제1유로 방향이며, 반대로 제1흐름제어체(1210)에서 제2흐름제어체(1220)로 향하는 유체 흐름이 제2유로 방향으로 정의한다.In the present invention, the fluid flow flowing from the second flow control body 1220 to the first flow control body 1210 is in the direction of the first flow path, and conversely, from the first flow control body 1210 to the second flow control body 1220 The directed fluid flow is defined as the second flow path direction.
밸브 본체(1100)는 단면이 원형 형상을 가지고 있으나, 다른 실시예에서는 사다리꼴 또는 직사각형 형상을 가질 수도 있다. 이 경우 흐름제어부(1200)의 형태도 변경될 수 있다.The valve body 1100 has a circular cross section, but may have a trapezoidal or rectangular shape in other embodiments. In this case, the shape of the flow control unit 1200 may also be changed.
흐름제어부(1200)는 밸브 본체(1100) 내 양방향 흐름제어를 제어할 수 있는 구성으로 되어 있으며, 흐름제어부(1200)의 구동에 따라 밸브 본체(1100) 내 유로의 폐쇄, 개방 및 개방방향의 결정이 이루어진다. 구체적인 흐름제어부(1200)의 구동에 대해서는 하기 도 7의 본 발명의 일실시예에 따른 양방향 흐름제어 밸브 흐름제어부의 동작에서 자세히 설명한다.The flow control unit 1200 is configured to control bidirectional flow control in the valve body 1100, and the flow control unit 1200 is driven to determine the closing, opening and opening directions of the flow path in the valve body 1100. This is done. The operation of the flow control unit 1200 will be described in detail in the operation of the flow control unit of the bidirectional flow control valve according to an embodiment of the present invention in FIG. 7.
제1흐름제어체(1210) 및 제2흐름제어체(1220)는 밸브 본체(1100) 내에서 유로 방향으로 이동가능하며 서로 마주하고 있다. 제1흐름제어체(1210) 및 제2흐름제어체(1220)의 외주면은 밸브 본체(1100)의 실질적으로 유체 흐름을 허용하지 않을 정도로 내주면과 밀착되어 있을 수 있다.The first flow control body 1210 and the second flow control body 1220 are movable in the flow path direction within the valve body 1100 and face each other. The outer circumferential surfaces of the first flow control body 1210 and the second flow control body 1220 may be in close contact with the inner circumferential surface so as not to allow fluid flow of the valve body 1100.
제1흐름제어체(1210)에는 제2흐름제어체(1220)를 노출시키는 제1관통공(1212)이 형성되어 있다. 제1관통공(1212)을 통하여 양 흐름제어체(1210, 1220)가 밀착한 상태에서 제2유로 방향으로 이동하는 유체흐름과 제2흐름제어체(1220)의 일부가 직접 접촉하게 된다. A first through hole 1212 is formed in the first flow control body 1210 to expose the second flow control body 1220. In a state in which both flow control bodies 1210 and 1220 are in close contact with each other through the first through hole 1212, the fluid flow moving in the direction of the second flow path and a part of the second flow control body 1220 directly contact each other.
제2흐름제어체(1220)에는 제1관통공(1212)과 연통하지 않는 제2관통공(1222)이 형성되어 있다. 제2관통공(1222)을 통하여 양 흐름제어체(1210, 1220)가 밀착한 상태에서 제1유로 방향으로 이동하는 유체흐름과 제1흐름제어체(1210)의 일부가 직접 접촉하게 된다.The second flow control body 1220 has a second through hole 1222 that does not communicate with the first through hole 1212. In a state in which both flow control bodies 1210 and 1220 are in close contact with each other through the second through hole 1222, the fluid flow moving in the direction of the first flow path and a part of the first flow control body 1210 directly contact each other.
본 실시예에서는 제1흐름제어체(1210) 중앙부에 하나의 관통공이, 제2흐름제어체(1220) 주변부에 다수의 관통공이 형성되어 있으나, 다른 실시예에서는 관통공의 크기, 형상, 위치 및 개수는 다양하게 변화될 수 있다.In this embodiment, one through hole is formed in the center of the first flow control body 1210 and a plurality of through holes are formed around the second flow control body 1220, but in other embodiments, the size, shape, location, and The number can be varied in various ways.
제1흐름제어체(1210)와 제2흐름제어체(1220)는 밸브 본체(1100) 내 유체흐름이 발생하지 않을 경우 서로 접촉하여 유로를 폐쇄하며, 유로에 일정 수준 이상의 유체 흐름이 발생하면, 제1흐름제어체(1210) 및 제2흐름제어체(1220)가 서로 이격하여 유로를 개방시키게 된다. The first flow control body 1210 and the second flow control body 1220 contact each other when no fluid flow occurs in the valve body 1100 to close the flow path, and when a fluid flow above a certain level occurs in the flow path, The first flow control body 1210 and the second flow control body 1220 are spaced apart from each other to open the flow path.
도 3 및 도 4에 도시된 바와 같이, 제1가압부재(1230)는 제1흐름제어체(1210)에 제2흐름제어체(1220) 방향으로 가압력을 제공하고, 제2가압부재(1240)는 제2흐름제어체(1220)에 제1흐름제어체(1210) 방향으로 가압력을 제공하게 된다. 3 and 4, the first pressing member 1230 provides a pressing force to the first flow control body 1210 in the direction of the second flow control body 1220, and the second pressing member 1240 Is to provide a pressing force to the second flow control body 1220 in the direction of the first flow control body 1210.
본 발명의 일실시예에서 제1가압부재(1230) 및 제2가압부재(1240)는 스프링으로 이루어져 있으며, 다른 실시예에서는 가압력을 제공할 수 있는 구성, 예를 들면 고무 등이 사용될 수 있다.In one embodiment of the present invention, the first pressing member 1230 and the second pressing member 1240 are made of a spring, and in another embodiment, a configuration capable of providing pressing force, for example, rubber, may be used.
도 4에 도시된 바와 같이, 스토퍼(1250)는 밸브 본체(1100)와 결합되어 있으며, 제1흐름제어체(1210) 및 제2흐름제어체(1220) 사이에 위치하고, 제1흐름제어체(1210) 및 제2흐름제어체(1220)가 밀착된 상태에서 제1흐름제어체(1210) 및 제2흐름제어체(1220)와 직접 접촉한다. 다른 실시예에서는 스토퍼(1250)의 일부는 밸브 본체(1100)내에서 이동가능하거나, 스토퍼(1250)는 흐름제어체(1210, 1220)의 밀착 상태에서 흐름제어체(1210, 1220)와 접촉하지 않을 수 있다.As shown in Figure 4, the stopper 1250 is coupled to the valve body 1100, is located between the first flow control body 1210 and the second flow control body 1220, the first flow control body ( 1210) and the second flow control body 1220 are in close contact with the first flow control body 1210 and the second flow control body 1220. In another embodiment, a part of the stopper 1250 is movable within the valve body 1100, or the stopper 1250 does not contact the flow control bodies 1210 and 1220 in a close contact with the flow control bodies 1210 and 1220. May not.
본 실시예와 같이 제1흐름제어체(1210) 및 제2흐름제어체(1220)가 밀착된 상태에서 스토퍼(1250)가 제1흐름제어체(1210) 및 제2흐름제어체(1220)와 직접 접촉하면, 흐름제어체(1210, 1220)와 스토퍼(1250)의 접촉에 의해 밀착상태에서 밀봉상태가 향상될 수 있다.In a state in which the first flow control body 1210 and the second flow control body 1220 are in close contact as in this embodiment, the stopper 1250 is connected to the first flow control body 1210 and the second flow control body 1220. When in direct contact, the sealing state may be improved in a close contact state by contacting the flow control bodies 1210 and 1220 and the stopper 1250.
스토퍼(1250)는 제1흐름제어체(1210)의 제2유로 방향으로의 이동을 제한하고, 제2흐름제어체(1220)의 제1유로 방향으로의 이동을 제한하게 된다. The stopper 1250 limits the movement of the first flow control body 1210 in the direction of the second flow path, and restricts the movement of the second flow control body 1220 in the direction of the first flow path.
스토퍼(1250)는 밸브 본체(1100) 내 양방향 유체 흐름을 크게 방해하지 않으면서, 제1흐름제어체(1210) 및 제2흐름제어체(1220)의 이동을 제한할 수 있는 형태라면 어떠한 형상도 가능하다.The stopper 1250 may have any shape as long as the movement of the first flow control body 1210 and the second flow control body 1220 is limited without significantly interfering with the flow of fluid in both directions in the valve body 1100. It is possible.
본 발명의 일실시예에서는 스토퍼(1250)가 밸브 본체(1100)와 결합되어 밸브 본체(1100) 내 어느 쪽으로도 이동하지 않는 것으로 나타나 있으나, 다른 실시예에서는 밸브 본체(1100) 내 유체 흐름에 따라 소폭 이동이 가능할 수도 있다.In one embodiment of the present invention, it is shown that the stopper 1250 is coupled to the valve body 1100 and does not move in any direction within the valve body 1100, but in another embodiment, according to the fluid flow in the valve body 1100 It may be possible to move slightly.
지지부(1262, 1264)는 제1가압부재(1230) 및 제2가압부재(1240)가 밸브 본체(1100) 내부에서 이탈되지 않도록 지지하는 역할을 하며, 제1가압부재(1230)의 제1유로 방향으로의 이동을 제한하는 제1지지부(1262), 제2가압부재(1240)의 제2유로 방향으로의 이동을 제한하는 제2지지부(1264)로 이루어져 있다.The support portions 1262 and 1264 serve to support the first pressing member 1230 and the second pressing member 1240 from being separated from the inside of the valve body 1100, and the first flow path of the first pressing member 1230 A first support portion 1262 restricting movement in the direction and a second support portion 1264 restricting movement of the second pressing member 1240 in the direction of the second passage.
제1지지부(1262) 및 제2지지부(1264)는 밸브 본체(1100)에 고정되어 있다.The first support portion 1262 and the second support portion 1264 are fixed to the valve body 1100.
제1가압부재(1230)는 제1지지부(1262)와 제1흐름제어체(1210) 사이에 위치하며, 제2가압부재(1240)는 제2지지부(1264)와 제2흐름제어체(1220) 사이에 위치하게 된다. The first pressing member 1230 is located between the first support portion 1262 and the first flow control body 1210, and the second pressing member 1240 includes a second support portion 1264 and a second flow control body 1220. ).
본 발명의 일실시예에서 지지부(1262, 1264)는 막대 3개가 겹쳐진 형태로 이루어져 있으나, 다른 실시예에서는 격자 및 십자가 등 다양한 형태로 마련될 수 있다. In one embodiment of the present invention, the support portions 1262 and 1264 are formed in a form in which three bars are overlapped, but in other embodiments, they may be provided in various forms such as a grid and a cross.
지지부(1262, 1264)는 양방향 유체흐름에 따른 제1가압부재(1230) 및 제2가압부재(1240)의 밸브 본체(1100) 내 이동 제한을 위한 구성으로서, 제1지지부(1262)가 제1가압부재(1230)와 접촉되어 있으며, 제2지지부(1264)가 제2가압부재(1240)와 접촉되어 있다.The support portions 1262 and 1264 are configured to limit movement of the first pressurizing member 1230 and the second pressurizing member 1240 in the valve body 1100 according to a bidirectional fluid flow, and the first support 1262 is a first It is in contact with the pressing member 1230, and the second support part 1264 is in contact with the second pressing member 1240.
밀착상태에서의 밀봉력을 향상시키기 위해 흐름제어체(1210, 1220) 중 하나는 비교적 부드러운 재질, 다른 하나는 딱딱한 재질로 이루어질 수 있다. 다른 실시예에서는 딱딱한 재질의 흐름제어체(1210, 1220)가 가압부재(1230, 1240)에 의해 파손되는 것을 방지하기 위한 버퍼부재(도시하지는 않았지만)를 더 포함할 수 있다. One of the flow control bodies 1210 and 1220 may be made of a relatively soft material and the other may be made of a hard material in order to improve the sealing force in the close contact state. In another embodiment, a buffer member (not shown) for preventing the flow control bodies 1210 and 1220 made of hard material from being damaged by the pressing members 1230 and 1240 may be further included.
버퍼부재(도시하지는 않았지만)는 제1가압부재(1230)와 제1흐름제어체(1210) 사이에 위치할 수도 있으며, 제2가압부재(1240)와 제2흐름제어체(1220) 사이에 위치할 수도 있다. The buffer member (though not shown) may be located between the first pressing member 1230 and the first flow control body 1210, and between the second pressing member 1240 and the second flow control body 1220 You may.
버퍼부재(도시하지는 않았지만)는 딱딱한 재질의 흐름제어체와 가압부재 사이의 완충역할을 하기 위한 재질로 구성, 예를 들면 실리콘 러버와 같은 고무 등이 사용될 수 있다.The buffer member (although not shown) is made of a material that serves as a buffer between the flow control body and the pressure member made of a hard material, and for example, rubber such as silicone rubber may be used.
본 발명에서 흐름제어체(1210, 1220)의 형상은 다양하게 변형될 수 있는데, 이를 도 6을 참조하여 설명한다.In the present invention, the shapes of the flow control bodies 1210 and 1220 may be variously modified, which will be described with reference to FIG. 6.
도 6은 본 발명의 일실시예에 따른 양방향 흐름제어 밸브에서 흐름제어체의 변형예를 나타낸 것이다.6 shows a modified example of the flow control body in the bidirectional flow control valve according to an embodiment of the present invention.
제1흐름제어체(1210)는 원판형상으로 제2흐름제어체(1220)는 구형상으로 되어 있다.The first flow control body 1210 has a disk shape and the second flow control body 1220 has a spherical shape.
다른 실시예에서의 제1흐름제어체(1210) 및 제2흐름제어체(1220)의 형상은 다양하게 변화될 수 있다.In another embodiment, the shapes of the first flow control body 1210 and the second flow control body 1220 may be variously changed.
도 7을 참조하여 본 발명의 일실시예에 따른 양방향 흐름제어 밸브 흐름제어부의 동작에 관하여 설명한다.With reference to Figure 7 will be described with respect to the operation of the bidirectional flow control valve flow control unit according to an embodiment of the present invention.
도 7은 본 발명의 일실시예에 따른 양방향 흐름제어 밸브 흐름제어부의 동작을 나타낸 것이다.7 illustrates the operation of a flow control unit of a bidirectional flow control valve according to an embodiment of the present invention.
도 7에 도시된 바와 같이, 제1흐름제어체(1210)와 제2흐름제어체(1220)는 밸브 본체(1100) 내 유체 흐름이 발생하지 않거나 일정 수준 이하의 유체 흐름(유체압)이 발생할 경우 서로 접촉하여 유로를 폐쇄하며, 유로에 일정 수준 이상의 유체 흐름(유체압)이 발생하면, 제1흐름제어체(1210) 및 제2흐름제어체(1220)가 서로 이격하여 유로를 개방시키게 된다. As shown in Figure 7, the first flow control body 1210 and the second flow control body 1220 does not generate a fluid flow in the valve body 1100 or a fluid flow (fluid pressure) below a certain level occurs. In this case, the flow path is closed by contacting each other, and when a fluid flow (fluid pressure) above a certain level occurs in the flow path, the first flow control body 1210 and the second flow control body 1220 are spaced apart from each other to open the flow path. .
유로에 유체 흐름이 발생하지 않은 폐쇄 상태에서는, 흐름제어부(1200)의 흐름제어체(1210, 1220) 및 가압부재(1230, 1240)는 밸브 본체(1100) 내부에서 움직임이 없는 상태로 있게 된다.In the closed state in which no fluid flow has occurred in the flow path, the flow control bodies 1210 and 1220 of the flow control unit 1200 and the pressure members 1230 and 1240 remain in a state where there is no movement inside the valve body 1100.
특히 제1흐름제어체(1210)및 제2흐름제어체(1220)는 가압력을 인가하는 가압부재(1230, 1240)에 의해 스토퍼(1250)를 가운데 두며, 서로 밀착된 상태로 있게 된다. 이러한 밀착 상태는 가압부재(1230, 1240)를 변형할 수 없을 정도의 유체 흐름(유체압)이 발생할 경우에만 유지된다.In particular, the first flow control body 1210 and the second flow control body 1220 have the stopper 1250 in the center by the pressing members 1230 and 1240 applying a pressing force, and are in close contact with each other. This close contact state is maintained only when a fluid flow (fluid pressure) such that the pressure members 1230 and 1240 cannot be deformed occurs.
제1유로 방향에서 일정수준 이상의 유체흐름이 발생하면, 제2흐름제어체(1220)에 형성되어 있는 제2관통공(1222)을 통해 제1유로 방향에서의 유체 흐름과 제1흐름제어체(1210)의 일부가 직접 접촉하게 된다.When a fluid flow of a certain level or more occurs in the direction of the first flow path, the fluid flow in the direction of the first flow path and the first flow control body (the second flow through hole 1222 formed in the second flow control body 1220) 1210) comes into direct contact.
이때, 제1흐름제어체(1210)에 제2흐름제어체(1220) 방향으로 가압력을 제공하던 제1가압부재(1230)가 축소변형되면서 제1흐름제어체(1210)가 제1유로 방향으로 이동하여 제2흐름제어체(1220)와 이격되면서 양 관통공(1212, 1222)을 통한 유로를 개방하게 된다. 여기서 제1가압부재(1230)는 제1지지부(1262)에 의해 이동이 제한되며, 제2흐름제어체(1220)는 스토퍼에 의해 움직임이 제한된다. At this time, the first pressurizing member 1230 that provided the pressing force to the first flow controller 1210 in the direction of the second flow controller 1220 is reduced and deformed, so that the first flow controller 1210 moves in the direction of the first flow path. It moves and is spaced apart from the second flow control body 1220 to open the flow path through both through holes 1212 and 1222. Here, the movement of the first pressing member 1230 is restricted by the first support portion 1262, and the movement of the second flow control body 1220 is restricted by the stopper.
제2유로 방향에서 일정수준 이상의 유체흐름이 발생하면 제1흐름제어체(1210)에 형성되어 있는 제1관통공(1212)을 통해 제2유로 방향에서의 유체흐름과 제2흐름제어체(1220)의 일부가 직접 접촉하게 된다. When a fluid flow exceeding a certain level occurs in the direction of the second flow path, the fluid flow in the direction of the second flow path and the second flow control body 1220 through the first through hole 1212 formed in the first flow control body 1210. ) Is in direct contact.
이때, 제2흐름제어체(1220)에 제1흐름제어체(1210) 방향으로 가압력을 제공하던 제2가압부재(1230)가 변형되면서 제2흐름제어체(1220)가 제2유로 방향으로 이동하여 제1흐름제어체(1220)와 이격되면서 양 관통공(1212, 1222)을 통한 유로를 개방하게 된다. 여기서 제2가압부재(1240)는 제2지지부(1264)에 의해 이동이 제한되며, 제1흐름제어체(1210)는 스토퍼에 의해 움직임이 제한된다. At this time, the second pressurizing member 1230 that provided the pressing force to the second flow controller 1220 in the direction of the first flow controller 1210 is deformed, and the second flow controller 1220 moves in the direction of the second flow path. Thus, while being spaced apart from the first flow controller 1220, the flow path through both through holes 1212 and 1222 is opened. Here, the movement of the second pressing member 1240 is restricted by the second support portion 1264, and the movement of the first flow control body 1210 is restricted by the stopper.
양방향 흐름 제어는 가압부재(1262, 1264)에 의해 움직임이 제한되어 있던 제1흐름제어체(1210) 및 제2흐름제어체(1220)가, 서로 다른 유체 흐름(양방향 유체 흐름)에 따라 가압부재(1262, 1264)가 변형되면서 제1유로 방향 또는 제2유로 방향으로 이동함으로써 밸브 본체(1100) 내 유로를 개방하게 된다. In the bidirectional flow control, the first flow control body 1210 and the second flow control body 1220, which were limited in motion by the pressing members 1262 and 1264, are pressurized members according to different fluid flows (bidirectional fluid flows). As 1262 and 1264 are deformed, the flow path in the valve body 1100 is opened by moving in the direction of the first flow passage or the direction of the second flow passage.
유로 개방 압력(유로)은 가압부재(1230, 1240)의 탄성 및 흐름제어체(1210, 1220)에 형성되어 있는 관통공(1212, 1222)의 면적, 형태 등을 조절함으로써 가능하게 된다.The flow path opening pressure (flow path) is made possible by adjusting the elasticity of the pressing members 1230 and 1240 and the area and shape of the through holes 1212 and 1222 formed in the flow control bodies 1210 and 1220.
본 발명에 따른 양방향 흐름제어 밸브는 단일 밸브의 사용만으로도 양방향 흐름제어가 가능하며, 단일 밸브의 사용으로 인한 소형화 및 단순화의 효과가 발생하게 된다.The two-way flow control valve according to the present invention enables two-way flow control only by using a single valve, and the effect of miniaturization and simplification occurs due to the use of a single valve.
이상 설명한 본 발명에 따른 뇌질환치료 시스템(1)의 작동에 대해 설명한다.The operation of the brain disease treatment system 1 according to the present invention described above will be described.
외부로부터의 지시 등에 따라 약물주입이 필요하면 제어부(240)는 유로전환기(234)를 제어하여 체내장치(10)와 약물투입부(220)를 연결하고 약물을 주입한다. 약물 주입에 의한 압력에 의해 양방향제어밸브(11)는 제2유로방향(뇌실방향)으로 유로가 형성되어 약물이 뇌실로 주입된다.When a drug injection is required according to an instruction from the outside, the controller 240 controls the flow path switch 234 to connect the internal device 10 and the drug injection unit 220 to inject the drug. The two-way control valve 11 forms a flow path in the direction of the second flow path (ventricular direction) by the pressure caused by the drug injection, so that the drug is injected into the ventricle.
이후 측정된 압력과 유량 등으로부터 계산된 뇌압이 일정수준을 넘는 것으로 판단되면 제어부(240)는 유로전환기(234)를 제어하여 체내장치(10)와 배액용기(210)를 연결한다. 뇌압에 의해 양방향제어밸브(11)는 제1유로방향(외부 방향)으로 유로가 형성되어 뇌척수액이 배액용기(210)로 배출된다.Then, when it is determined that the brain pressure calculated from the measured pressure and flow rate exceeds a certain level, the controller 240 controls the flow path switch 234 to connect the internal device 10 and the drainage container 210. The bidirectional control valve 11 forms a flow path in the direction of the first flow path (outside) by the brain pressure, so that the cerebrospinal fluid is discharged into the drainage container 210.
이상 설명한 본 발명에 따르면 양방향 허용압력을 가지는 체내장치(10) 및 내부 압력조정이 가능한 배액용기(210)를 사용하여 투약 및 장기 배액이 가능하다. 또한 뇌실-복강경단락술이 요구하는 복잡한 시술이 없이도 한 번의 체내장치(10) 이식 수술로 약물 주입과 배액을 수행할 수 있으며, 뇌압 측정을 장기간 동안 반복적으로 수행할 수 있다.According to the present invention described above, administration and long-term drainage are possible by using the internal device 10 having an allowable pressure in both directions and the drainage container 210 capable of adjusting the internal pressure. In addition, it is possible to perform drug injection and drainage through a single implantation operation of the internal body device 10 without the complicated procedure required by ventricular-laparoscopic shunting, and measurement of brain pressure can be repeatedly performed for a long time.
도 8을 참조하여 본 발명의 일실시예에 따른 뇌질환 치료 시스템의 변형 사용예를 설명한다.A modified use example of the brain disease treatment system according to an embodiment of the present invention will be described with reference to FIG. 8.
약물 치료가 더 이상 필요하지 않을 경우, 도 8과 같이 체외장치(20)에서 유체라인(231)과 배액용기(210) 만을 제외하고 모두 제거할 수 있다. 체내장치(10)에는 장기 배액시 일정한 압력을 초과할 때만 외부방향 흐름을 허용하는 양방향흐름제어밸브(11)가 있기 때문에 간단한 구성만으로 장기적인 배액이 가능하다.When drug treatment is no longer required, all except for the fluid line 231 and the drainage container 210 from the external device 20 as shown in FIG. 8 may be removed. Since the internal device 10 has a two-way flow control valve 11 that allows external flow only when a certain pressure is exceeded during long-term drainage, long-term drainage is possible with only a simple configuration.
한편 본 발명은 앞서 설명한 바와 같은 뇌질환 치료 방법을 제공한다.Meanwhile, the present invention provides a method for treating brain diseases as described above.
앞에서 설명되고, 도면에 도시된 본 발명의 실시예는, 본 발명의 기술적 사상을 한정하는 것으로 해석되어서는 안 된다. 본 발명의 보호범위는 청구범위에 기재된 사항에 의하여만 제한되고, 본 발명의 기술분야에서 통상의 지식을 가진 자는 본 발명의 기술적 사상을 다양한 형태로 개량 변경하는 것이 가능하다. 따라서 이러한 개량 및 변경은 통상의 지식을 가진 자에게 자명한 것인 한 본 발명의 보호 범위에 속하게 될 것이다.Embodiments of the present invention described above and shown in the drawings should not be construed as limiting the technical idea of the present invention. The protection scope of the present invention is limited only by the matters described in the claims, and those of ordinary skill in the technical field of the present invention can improve and change the technical idea of the present invention in various forms. Therefore, such improvements and changes will fall within the scope of protection of the present invention as long as it is apparent to those of ordinary skill in the art.

Claims (17)

  1. 양방향 흐름제어 밸브에 있어서,In the two-way flow control valve,
    유체가 이동하는 유로를 형성하는 밸브 본체와;A valve body forming a flow path through which fluid moves;
    상기 밸브 본체 내에 위치하는 흐름제어부를 포함하며,It includes a flow control unit located in the valve body,
    상기 흐름제어부는,The flow control unit,
    유로 방향으로 이동가능하며 서로 마주하는 제1흐름제어체 및 제2흐름제어체; A first flow control body and a second flow control body that are movable in a flow direction and face each other;
    상기 제1흐름제어체에 상기 제2흐름제어체 방향으로 가압력을 제공하는 제1가압부재;A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller;
    상기 제2흐름제어체에 상기 제1흐름제어체 방향으로 가압력을 제공하는 제2가압부재를 포함하며,And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body,
    상기 제1흐름제어체와 상기 제2흐름제어체가 밀착된 상태에서,In a state in which the first flow control body and the second flow control body are in close contact,
    상기 제1흐름제어체의 일부는 제2흐름제어체에서 상기 제1흐름제어체를 향하는 제1유로 방향의 유체흐름에 직접 접촉하며,A part of the first flow control body directly contacts the fluid flow in the direction of the first flow passage from the second flow control body toward the first flow control body,
    상기 제2흐름제어체의 일부는 제1방향과 반대방향인 제2유로 방향의 유체흐름에 직접 접촉하는 양방향 흐름제어 밸브.A portion of the second flow control body is a two-way flow control valve that directly contacts the fluid flow in the second flow path direction opposite to the first direction.
  2. 제1항에 있어서, The method of claim 1,
    상기 제1흐름제어체와 상기 제2흐름제어체는 접촉하여 상기 유로를 폐쇄하며,The first flow control body and the second flow control body contact to close the flow path,
    상기 유로에 일정 수준 이상의 유체 흐름이 발생하면, When a fluid flow above a certain level occurs in the flow path,
    상기 제1흐름제어체 및 상기 제2흐름제어체가 서로 이격하여 상기 유로를 개방하는 것을 특징으로 하는 양방향 흐름제어 밸브.The first flow control body and the second flow control body are spaced apart from each other to open the flow path.
  3. 제1항에서,In claim 1,
    상기 제1가압부재 및 제2가압부재는 탄성력을 가지고 있는 탄성체로 이루어져 있으며, The first pressing member and the second pressing member are made of an elastic body having an elastic force,
    상기 제1유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1가압부재가 변형되면서 상기 제1흐름제어체가 상기 제1유로 방향으로 이동하여 상기 유로를 개방하고, When a fluid flow of more than a certain level occurs in the direction of the first flow path, the first pressure member is deformed and the first flow controller moves in the direction of the first flow path to open the flow path,
    상기 제2유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제2가압부재가 변형되면서 상기 제2흐름제어체가 상기 제2유로 방향으로 이동하여 상기 유로를 개방하는 것을 특징으로 하는 양방향 흐름제어 밸브.A bidirectional flow control valve, characterized in that when a fluid flow of more than a certain level occurs in the direction of the second flow path, the second pressure member is deformed and the second flow control member moves in the direction of the second flow path to open the flow path. .
  4. 제1항에서,In claim 1,
    상기 흐름제어부는,The flow control unit,
    상기 제1흐름제어체 및 상기 제2흐름제어체 사이에 위치하는 스토퍼를 더 포함하며,Further comprising a stopper positioned between the first flow control body and the second flow control body,
    상기 스토퍼는,The stopper,
    상기 제1흐름제어체의 상기 제2유로 방향으로의 이동을 제한하고, Limiting the movement of the first flow control body in the direction of the second flow path,
    상기 제2흐름제어체의 상기 제1유로 방향으로의 이동을 제한하는 것을 특징으로 하는 양방향 흐름제어 밸브.Bidirectional flow control valve, characterized in that to limit the movement of the second flow control body in the direction of the first flow path.
  5. 제1항에서,In claim 1,
    상기 흐름제어부는,The flow control unit,
    상기 가압부재의 이동을 제한하는 지지부를 더 포함하며,Further comprising a support for limiting the movement of the pressing member,
    상기 지지부는,The support part,
    상기 제1가압부재의 상기 제1유로 방향으로의 이동을 제한하는 제1지지부;A first support portion for restricting movement of the first pressing member in the direction of the first passage;
    상기 제2가압부재의 상기 제2유로 방향으로의 이동을 제한하는 제2지지부를 포함하는 것을 특징으로 하는 양방향 흐름제어 밸브.And a second support portion restricting movement of the second pressure member in the direction of the second flow path.
  6. 제1항에서,In claim 1,
    상기 제1흐름제어체에는 상기 제2흐름제어체를 상기 제2유로 방향의 유체흐름에 노출시키는 제1관통공이 형성되어 있으며,The first flow control body has a first through hole for exposing the second flow control body to a fluid flow in the direction of the second flow path,
    상기 제2흐름제어체에는 상기 제1관통공과 연통하지 않으며 상기 제1흐름제어체를 상기 제1유로 방향의 유체흐름에 노출시키는 제2관통공이 형성되어 있는 양방향 흐름제어 밸브.A two-way flow control valve in which a second through hole is formed in the second flow control body, which does not communicate with the first through hole and exposes the first flow control body to a fluid flow in the direction of the first flow path.
  7. 뇌질환치료 시스템에 있어서,In the brain disease treatment system,
    환자의 두개골 내에 이식되며, 양방향 흐름제어 밸브를 포함하는 체내장치; 및An internal device implanted into the patient's skull and including a two-way flow control valve; And
    환자의 두개골 외에 위치하며, 상기 체내장치에 약물을 공급하거나 상기 체내장치로부터 뇌척수액을 배출하는 체외장치를 포함하며,It is located outside the skull of the patient, and includes an extracorporeal device for supplying drugs to the internal device or discharging cerebrospinal fluid from the internal device,
    상기 체외장치는,The extracorporeal device,
    펌프를 포함하는 약물투입부;Drug injection unit including a pump;
    체외로 배출된 뇌척수액을 보관하는 배액용기;Drainage container for storing cerebrospinal fluid discharged from the body;
    상기 체내장치를 상기 약물투입부 및 상기 배액용기에 연결하는 연결부; 및A connection part connecting the internal device to the drug injection part and the drainage container; And
    상기 연결부의 작동을 제어하는 제어부를 포함하는 뇌질환치료 시스템.Brain disease treatment system comprising a control unit for controlling the operation of the connection unit.
  8. 제7항에 있어서,The method of claim 7,
    상기 양방향 흐름제어 밸브는,The bidirectional flow control valve,
    유체가 이동하는 유로를 형성하는 밸브 본체와;A valve body forming a flow path through which fluid moves;
    상기 밸브 본체 내에 위치하는 흐름제어부를 포함하며,It includes a flow control unit located in the valve body,
    상기 흐름제어부는,The flow control unit,
    유로 방향으로 이동가능하며 서로 마주하는 제1흐름제어체 및 제2흐름제어체; A first flow control body and a second flow control body that are movable in a flow direction and face each other;
    상기 제1흐름제어체에 상기 제2흐름제어체 방향으로 가압력을 제공하는 제1가압부재;A first pressing member for providing a pressing force to the first flow controller in the direction of the second flow controller;
    상기 제2흐름제어체에 상기 제1흐름제어체 방향으로 가압력을 제공하는 제2가압부재를 포함하며,And a second pressing member for providing a pressing force to the second flow control body in a direction of the first flow control body,
    상기 제1흐름제어체와 상기 제2흐름제어체가 밀착된 상태에서,In a state in which the first flow control body and the second flow control body are in close contact,
    상기 제1흐름제어체의 일부는 제2흐름제어체에서 상기 제1흐름제어체를 향하는 제1유로 방향의 유체흐름에 직접 접촉하며,A part of the first flow control body directly contacts the fluid flow in the direction of the first flow passage from the second flow control body toward the first flow control body,
    상기 제2흐름제어체의 일부는 제1방향과 반대방향인 제2유로 방향의 유체흐름에 직접 접촉하는 뇌질환치료 시스템.A brain disease treatment system in which a part of the second flow control body directly contacts the fluid flow in a second flow path direction opposite to the first direction.
  9. 제7항에 있어서,The method of claim 7,
    상기 연결부는,The connection part,
    상기 체내장치와 상기 약물투입부 및 상기 배액용기를 연결하는 유체라인; 및A fluid line connecting the internal device to the drug injection unit and the drain container; And
    상기 유체라인 상에 위치하며, 상기 체내장치를 상기 약물투입부 및 상기 배액용기에 선택적으로 연결하는 유로전환기를 포함하며,It is located on the fluid line, and includes a flow path switch for selectively connecting the internal device to the drug injection unit and the drain container,
    상기 제어부는 상기 유로전환기의 작동을 제어하는 뇌질환치료 시스템.The control unit is a brain disease treatment system for controlling the operation of the flow path switch.
  10. 제9항에 있어서,The method of claim 9,
    상기 연결부는,The connection part,
    상기 유체라인의 유량을 측정하는 유량계; 및A flow meter measuring the flow rate of the fluid line; And
    상기 유체라인의 압력을 측정하는 압력계를 더 포함하며,Further comprising a pressure gauge for measuring the pressure of the fluid line,
    상기 제어부는 상기 유량계 및 상기 압력계의 측정결과를 기초로 상기 유로전환기의 작동을 제어하는 뇌질환치료 시스템.The control unit is a brain disease treatment system for controlling the operation of the flow path switch based on the measurement result of the flow meter and the pressure meter.
  11. 제9항에 있어서,The method of claim 9,
    상기 제어부는 상기 유량계 및 상기 압력계의 측정결과로부터 뇌압을 계산하며,The control unit calculates the brain pressure from the measurement results of the flow meter and the pressure meter,
    계산된 뇌압이 일정한 값을 넘으면 상기 체내장치를 상기 배액용기에 연결되어 뇌척수액이 배출되도록 상기 유로전환기의 작동을 제어하는 뇌질환치료 시스템.When the calculated brain pressure exceeds a certain value, the internal device is connected to the drainage container to control the operation of the flow path switch so that cerebrospinal fluid is discharged.
  12. 제9항에 있어서,The method of claim 9,
    상기 배액백은 일정 압력으로 가압되어 있는 뇌질환치료 시스템.The drainage bag is a brain disease treatment system that is pressurized at a certain pressure.
  13. 제8항에 있어서, The method of claim 8,
    상기 제1흐름제어체와 상기 제2흐름제어체는 접촉하여 상기 유로를 폐쇄하며,The first flow control body and the second flow control body contact to close the flow path,
    상기 유로에 일정 수준 이상의 유체 흐름이 발생하면, When a fluid flow above a certain level occurs in the flow path,
    상기 제1흐름제어체 및 상기 제2흐름제어체가 서로 이격하여 상기 유로를 개방하는 것을 특징으로 하는 뇌질환치료 시스템.The brain disease treatment system, characterized in that the first flow control body and the second flow control body are spaced apart from each other to open the flow path.
  14. 제8항에서,In clause 8,
    상기 제1가압부재 및 제2가압부재는 탄성력을 가지고 있는 탄성체로 이루어져 있으며, The first pressing member and the second pressing member are made of an elastic body having an elastic force,
    상기 제1유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제1가압부재가 변형되면서 상기 제1흐름제어체가 상기 제1유로 방향으로 이동하여 상기 유로를 개방하고, When a fluid flow of more than a certain level occurs in the direction of the first flow path, the first pressure member is deformed and the first flow controller moves in the direction of the first flow path to open the flow path,
    상기 제2유로 방향으로 일정 수준 이상의 유체 흐름이 발생하면, 상기 제2가압부재가 변형되면서 상기 제2흐름제어체가 상기 제2유로 방향으로 이동하여 상기 유로를 개방하는 것을 특징으로 하는 뇌질환치료 시스템.A brain disease treatment system, characterized in that when a fluid flow of more than a certain level occurs in the direction of the second flow path, the second pressure member is deformed and the second flow controller moves in the direction of the second flow path to open the flow path. .
  15. 제8항에서,In clause 8,
    상기 흐름제어부는,The flow control unit,
    상기 제1흐름제어체 및 상기 제2흐름제어체 사이에 위치하는 스토퍼를 더 포함하며,Further comprising a stopper positioned between the first flow control body and the second flow control body,
    상기 스토퍼는,The stopper,
    상기 제1흐름제어체의 상기 제2유로 방향으로의 이동을 제한하고, Limiting the movement of the first flow control body in the direction of the second flow path,
    상기 제2흐름제어체의 상기 제1유로 방향으로의 이동을 제한하는 것을 특징으로 하는 뇌질환치료 시스템.Brain disease treatment system, characterized in that limiting the movement of the second flow controller in the direction of the first flow path.
  16. 제8항에서,In clause 8,
    상기 흐름제어부는,The flow control unit,
    상기 가압부재의 이동을 제한하는 지지부를 더 포함하며,Further comprising a support for limiting the movement of the pressing member,
    상기 지지부는,The support part,
    상기 제1가압부재의 상기 제1유로 방향으로의 이동을 제한하는 제1지지부;A first support portion for restricting movement of the first pressing member in the direction of the first passage;
    상기 제2가압부재의 상기 제2유로 방향으로의 이동을 제한하는 제2지지부를 포함하는 것을 특징으로 하는 뇌질환치료 시스템.A brain disease treatment system comprising a second support for limiting the movement of the second pressing member in the direction of the second passage.
  17. 제8항에서,In clause 8,
    상기 제1흐름제어체에는 상기 제2흐름제어체를 상기 제2유로 방향의 유체흐름에 노출시키는 제1관통공이 형성되어 있으며,The first flow control body has a first through hole for exposing the second flow control body to a fluid flow in the direction of the second flow path,
    상기 제2흐름제어체에는 상기 제1관통공과 연통하지 않으며 상기 제1흐름제어체를 상기 제1유로 방향의 유체흐름에 노출시키는 제2관통공이 형성되어 있는 것을 특징으로 하는 뇌질환치료 시스템.The brain disease treatment system, wherein the second flow control body has a second through hole that does not communicate with the first through hole and exposes the first flow control body to the fluid flow in the direction of the first flow path.
PCT/KR2020/004405 2019-04-01 2020-03-31 Bidirectional flow control valve and brain disease treatment system comprising same WO2020204574A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR1020190038033A KR102201288B1 (en) 2019-04-01 2019-04-01 System for treating brain disease
KR10-2019-0038034 2019-04-01
KR1020190038034A KR102151207B1 (en) 2019-04-01 2019-04-01 Bidirectional flow control valve
KR10-2019-0038033 2019-04-01

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WO2020204574A1 true WO2020204574A1 (en) 2020-10-08

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681559A (en) * 1985-12-23 1987-07-21 Cordis Corporation Plural valve three stage pressure relief system
KR100255133B1 (en) * 1996-08-29 2000-10-02 정몽규 Check valve having bilateral way
KR20070047909A (en) * 2005-11-03 2007-05-08 주식회사 만도 Relief valve and shock absorber of use it
KR101839806B1 (en) * 2016-09-30 2018-03-19 서강대학교산학협력단 Implantable drug infusion device with bidirectional flow control safety valve and system using the same
KR101920829B1 (en) * 2017-04-26 2018-11-21 국립암센터 Auto drainage system of cerebrospinal fluid FOR IMPLANTING SKULL

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681559A (en) * 1985-12-23 1987-07-21 Cordis Corporation Plural valve three stage pressure relief system
KR100255133B1 (en) * 1996-08-29 2000-10-02 정몽규 Check valve having bilateral way
KR20070047909A (en) * 2005-11-03 2007-05-08 주식회사 만도 Relief valve and shock absorber of use it
KR101839806B1 (en) * 2016-09-30 2018-03-19 서강대학교산학협력단 Implantable drug infusion device with bidirectional flow control safety valve and system using the same
KR101920829B1 (en) * 2017-04-26 2018-11-21 국립암센터 Auto drainage system of cerebrospinal fluid FOR IMPLANTING SKULL

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