WO2019103453A2 - Oil-in-water cosmetic composition containing high-content calamine stabilized in inner phase - Google Patents

Oil-in-water cosmetic composition containing high-content calamine stabilized in inner phase Download PDF

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WO2019103453A2
WO2019103453A2 PCT/KR2018/014352 KR2018014352W WO2019103453A2 WO 2019103453 A2 WO2019103453 A2 WO 2019103453A2 KR 2018014352 W KR2018014352 W KR 2018014352W WO 2019103453 A2 WO2019103453 A2 WO 2019103453A2
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Prior art keywords
sorbitan
surfactant
cosmetic composition
calamine
oil
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PCT/KR2018/014352
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French (fr)
Korean (ko)
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WO2019103453A3 (en
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박안나
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주식회사 아모레퍼시픽
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Priority to CN201880075382.0A priority Critical patent/CN111479547B/en
Publication of WO2019103453A2 publication Critical patent/WO2019103453A2/en
Publication of WO2019103453A3 publication Critical patent/WO2019103453A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to an underwater type cosmetic composition in which a high content of calamine is stabilized in the inner phase by using a combination of a sorbitan surfactant and a sugar surfactant.
  • the present invention also relates to the use of a mixture of a sorbitan surfactant and a saccharide surfactant as an internal stabilizer in the preparation of an underwater type cosmetic composition containing a high content of calamine in the interior.
  • the present invention also relates to a method for stabilizing high-content calamine in the in-vivo type cosmetic composition.
  • the present invention relates to a method for maximizing the functional activity of a calamine by applying a high-content, in-vivo calamine-stabilized underwater-type cosmetic composition according to the present invention to the skin.
  • Calamine is a light pink fine powder obtained by mixing zinc oxide with 0.5 ⁇ 1% iron oxide (III). Zinc oxide contained in the calamine has an anti-inflammatory and protective action. Therefore, calamine is contained in external preparations for skin such as ointment and spraying agent, and is used as a protective agent for treating skin diseases, an astringent agent, and an antiseptic agent. In the field of cosmetics, it is contained in a calamine lotion base and is used for the purpose of improving acne skin and soothing the skin.
  • Korean Patent No. 10-1590803 discloses a cosmetic composition for improving immediate whitening or complexion containing calamine.
  • this patent also adopts a water-in-oil type rather than an underwater type as an effective formulation.
  • the key to stabilizing the calamine in water-in-oil formulations and enhancing its long-term stability is to overcome the phenomenon of precipitation of the polymer and calamine into the particles and gelling of the polymer.
  • the calamine was separated from the outer surface of the polymer and stabilized inward.
  • a method of using a calorimine-based surfactant and a sugar-based surfactant together thereby securing a long-term stability by stabilizing a high content of calamine in the inner phase of an underwater type cosmetic, It is also possible to improve.
  • Patent Document 1 Korean Patent No. 10-1590803
  • the present inventors tried to prepare a cosmetic stabilized with a high content of colorini in water type in order to obtain improved feeling than the conventional water-in-oil type colorin cosmetic.
  • the gelation phenomenon of the polymer became a problem.
  • a method of dispersing the polymer and the calamine in different phases was devised.
  • an object of the present invention to provide an underwater-type cosmetic composition which stabilizes a high-content coloramine in the interior.
  • the present invention provides a water-in-oil cosmetic composition stabilized with a high content of calamine by stabilizing the calamine in the inner phase by containing a calamine, a sorbitan surfactant and a sugar-based surfactant.
  • the present invention also provides the use of a mixture of a sorbitan surfactant and a saccharide surfactant as an internal stabilizer in the preparation of an underwater-type cosmetic composition containing a high content of calamine in the inner layer.
  • the present invention also provides a method for stabilizing high-content calamine in the in-vivo type cosmetic composition. Further, the present invention provides a method for maximizing the functional activity of a calamine by applying a high-calorie-stabilized water-in-oil type cosmetic composition according to the present invention to the skin.
  • the cosmetic composition according to the present invention can increase the stability and long-term stability of a calamine-containing oil-in-water preparation by using a combination of a sorbitan surfactant and a sugar surfactant.
  • a sorbitan surfactant e.g., sorbitan surfactant
  • sugar surfactant e.g., sorbitan surfactant
  • the high-content calamine can be stabilized to the inner phase of the water type, it is possible to improve the feeling of bad feeling such as stiffness and the skin absorbency.
  • FIG. 1 is a photograph of the appearance of a composition for observing the degree of separation between water phase and oil phase after storing Example 1 and Comparative Examples 1 to 5 at 45.degree. C. for 2 weeks after production.
  • Fig. 2 is a photograph of the appearance of a cream-like appearance stabilized in an underwater type with the composition of Example 1.
  • the present invention relates to an underwater type cosmetic composition containing a calamine, a sorbitan surfactant and a sugar surfactant and stabilizing a high-content calamine in the inner phase.
  • Calamine which is contained as an effective ingredient in cosmetics, is a fine powder with a light pink color. It is mainly used for improving acne skin and soothing skin. It is also known to exhibit whitening effect and moisturizing effect by being included in a water-in-oil type cosmetic material.
  • the present invention provides a cosmetic composition which contains a high content of calamine having such an effect and which is stabilized in the in-water type, which is not a water-in-oil type.
  • the calamine may be contained in an amount of 0.01 to 15% by weight, preferably 5 to 15% by weight based on the total weight of the composition. If the content of the columbium is more than 15% by weight, the dispersion stability may be lowered. If the content of the columbium is less than 0.01% by weight, the effect of the skin due to the coloramine may be insignificant.
  • the above-mentioned calamine may be a commercially available raw material, or a modified calamine which can be prepared by a conventional method by controlling the compounding ratio of components constituting the calamine.
  • a nonionic surfactant is used to stabilize the calamine in the water-in-oil type, and at least one of a sugar surfactant and at least one sorbitan surfactant is used together with the nonionic surfactant.
  • the sugar type surfactant refers to an alkyl polyglycoside (APGs) type surfactant, a sugar ester type surfactant, or a mixture thereof.
  • APGs alkyl polyglycoside
  • alkylpolyglycosides in the alkylpolyglycoside surfactants refer to general alkylpolyglycosides represented by the following general formula (1).
  • the alkylpolyglycoside surfactant may include a mixture of an alkyl polyglycoside represented by the following formula (1) and a fatty alcohol.
  • the sugar ester is mainly a saccharide fatty acid ester, and refers to a substance in which a fatty acid of C10-C30 fatty acid, preferably C12-C26, is ester-bonded to glucose.
  • the sugar ester surfactant includes an ester compound produced by bonding a fatty acid with a condensation reaction product of sugar and other substances together with a common sugar fatty acid ester.
  • the alkyl polyglycoside surfactant may be at least one selected from surfactants composed of a mixture of C6-C30 higher alcohol and C10-C30 glucoside derivative. More particularly, the present invention relates to a method for producing a C14-22 alcohol * C12-20 alkyl glucoside, Cetearyl Alcohol and Cetearyl Glucoside, a behenyl alcohol * It may be at least one selected from the group consisting of arachidyl glucoside, behenyl alcohol and arachidyl alcohol and arachidyl glucoside, cetearyl alcohol and coco-glucoside.
  • the sugar ester surfactant may be polyglyceryl-3 methylglucose distearate.
  • the above-mentioned saccharide-type surfactant may be prepared by using Cetearyl Alcohol * Cetearyl Glucoside alone as the alkylpolyglycoside surfactant, Alternatively, the polyglyceryl-3 methylglucose distearate may be used together with the above-mentioned cetearyl alcohol * cetearyl glucoside and the sugar ester surfactant.
  • the sugar-based surfactant used in the present invention serves to stabilize oil-in-water (O / W) emulsified particles.
  • the cetearyl alcohol * Cetearyl Glucoside which can be used in the present invention, is a surfactant having a higher content of fatty alcohols including cetearyl alcohol, and the fatty alcohol Plays a role of keeping the interface film harder while forming liquid crystals around the O / W interface film formed by cetearyl glucoside. Therefore, it is possible to maintain the emulsion stability even under harsh conditions or for a long period of storage, and thus it can be an important component for preventing the aggregation or separation of chromamine in the present invention.
  • the saccharide-based surfactant may be contained in an amount of 0.1 to 8% by weight, preferably 1 to 5% by weight, based on the total weight of the composition. If the amount of the sugar-based surfactant exceeds 8% by weight, the formulation may not be formed, and if it is less than 0.1% by weight, the surfactant may have a small role.
  • the sorbitan surfactant includes a sorbitan ester and an addition polymer of sorbitan ester and ethylene oxide.
  • the sorbitan esters are usually classified as sugar type surfactants, but the sorbitan esters and / or the polymer components of the sorbitan esters are classified as important because they greatly affect the formulation stability of the cosmetic composition according to the present invention.
  • a sorbitan fatty acid ester such as sorbitan olivate, sorbitan stearate, sorbitan is
  • the sorbitan surfactant used in the present invention has the function of increasing the dispersibility so that the calamine powder is well dispersed in the water-in-oil type. Particularly, when a combination of sorbitan ester and polysorbate, which is a surface active agent grafted with polyethylene glycol (PEG) having a very high surfactant activity, is used in combination, a high content of calamine is stabilized in the in- It can be very effective in doing so.
  • PEG polyethylene glycol
  • the sorbitan surfactant may be contained in an amount of 0.01 to 5% by weight, preferably 0.5 to 4% by weight based on the total weight of the composition. If the content of the sorbitan surfactant is more than 5% by weight, it may interfere with the formation of the formulations, and if it is less than 0.01% by weight, it is difficult to expect the dispersibility improving ability.
  • the cosmetic composition according to the present invention it is preferable that one or more of the above-mentioned saccharide surfactant and the above-mentioned sorbitan surfactant are used together, and when only a saccharide surfactant is used or only a sorbitan surfactant is used,
  • the underwater type formulation may not be well formed or the stability may be significantly deteriorated.
  • the mixing ratio of the saccharide-based surfactant and the sorbitan-based surfactant is 2.5: 0.6 to 2.5 based on the weight, excellent formulation stability and long-term stability can be exhibited.
  • nonionic surfactants instead of the sorbitan surfactants or to use anionic surfactants in the cosmetic composition according to the present invention.
  • PEG-100 Stearate or Glyceryl MonoStearate which is a non-ionic surfactant commonly used, or when an anionic surfactant such as glyceryl stearate
  • anionic surfactant such as glyceryl stearate
  • Glyceryl Stearate Citrate or Potassium Cetyl Phosphate it is difficult to stabilize the calamine in the water-in-oil type alone without mixing the sugar surfactant and the sorbitan surfactant, The long-term stability may be lowered even if the formulation is not formed at the time of manufacture and is immediately separated or the formulation is formed.
  • the cosmetic composition according to the present invention may further comprise an oil, a polyol, an aging agent, water, etc., in addition to the calamine and the saccharide-based or sorbitan-based surfactant.
  • the oil may contain, for example, an ester-based or hydrocarbon-based oil in an amount of about 10% by weight or more based on the total weight of the composition in order to impart adequate moisture.
  • the polyol may be contained in an amount of 5 to 15% by weight based on the total weight of the composition.
  • the thickening agent examples include hydroxyethyl methacrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyltaurate / VP copolymer, and the like.
  • Polyacrylates such as Polyacrylate Crosspolymer-6, Polyacrylate-13, and Sodium Poylacrylate may be used.
  • the composition may be used in a total amount of the composition 0.1 to 3 % By weight.
  • polyacrylates When polyacrylates are used as an incremental agent in the cosmetic composition according to the present invention, it may be more advantageous in formulation stability of an underwater type than using a carbomer-based thickener.
  • a carbomer-based thickener When using a carbomer-based thickener in an underwater type, it is easily influenced by electric charges and becomes more easily entangled with a powder such as a calamine, which may deteriorate the quality.
  • the cosmetic composition according to the present invention may further include at least one selected from the group consisting of moisturizers, pigments, fragrances, preservatives and other additives commonly used in cosmetics, in addition to the above components.
  • the water-in-oil type is an oil-in-water (O / W) type emulsion form in which the external phase (continuous phase)
  • the colocalimin is prepared to be contained in the intestine.
  • the water-in-oil type cosmetic composition according to the present invention is prepared by dissolving a water-based component and an oil-based component at room temperature, emulsifying the oil-based part in an aqueous phase, and dispersing it in an oil-based component. Then, the emulsified contents may be cooled, and then the thickening agent may be added and dispersed.
  • the water-in-oil type cosmetic composition according to the present invention produced by the above-mentioned method can keep long-term stability for 12 months or longer without precipitation of particles or separation of formulations even at high temperature of 45 ° C and high-speed mixing at 9,000 rpm.
  • the cosmetic composition of the present invention stabilized in accordance with the above method can improve feeling of use such as spreadability and improve skin absorbency.
  • the underwater type cosmetic composition according to the present invention may be formulated into an essence, lotion, cream, or night form to be applied or sprayed on the skin or mucous membranes, without any particular limitation, and may be moisturized, whitened, Sedative, or sensitive skin, and the like.
  • the water-in-oil type cosmetic compositions of Examples 1 to 7 and Comparative Examples 1 to 5 were prepared by the following production methods according to the contents and contents shown in Tables 1 and 2 below.
  • Calamin (manufactured by Jufa Biocell Co., Ltd.) was used as the calamine, and cetearyl alcohol * cetearyl glucoside (Montanov 68, Seppic Co., France) and / or Polyglyceryl-3 methylglucoside distearate (Tego care 450, manufactured by Evonik) was used in the examples.
  • the sorbitan surfactant was sorbitan olivate (Olivem 1000, manufactured by B & T) and / or polysorbate 60 (TWEEN # 60 V, manufactured by CRODA) was used.
  • the calamine is dispersed in the oil-based part, not in the water-based part.
  • Example 1 Example 2
  • Example 3 Example 4
  • Example 6 Example 7 Paid Efficacy component Calamine 5 10 15 5 5 5 10
  • Surfactants Cetearyl Alcohol * Cetearyl Glucoside 2.5 2.5 2.5 2.5 One 2 2.5 2.5
  • Examples 1 to 7 and Comparative Examples 1 to 5 were evaluated using a low temperature incubator LTI-1001SD (product name of EYELA) at a temperature of -15 DEG C to 45 DEG C for 24 hours, And the accelerated stability of the formulation was evaluated.
  • LTI-1001SD product name of EYELA
  • Example 1 Example 2
  • Example 3 Example 4
  • Example 5 Example 6
  • Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Stability (45 °C) X X ⁇ ⁇ X Acceleration stability X X ⁇ ⁇ X
  • Examples 1 to 7 which contain a high content of calamine in an amount of 5 to 15% by weight and contain a saccharide-based surfactant and a sorbitan-based surfactant, And both of high temperature stability and acceleration stability showed excellent results.
  • the content of the calamine was increased by 2 times and 3 times, respectively, based on Example 1, and the sorbitan surfactant effective for the dispersion of the calamine was increased and prespecified. As a result, It was confirmed that a formulation having excellent stability was obtained even when it reached 15% by weight.
  • the mixing ratio of the saccharide surfactant and the sorbitan surfactant at this time was preferably 2.5: 0.6 to 2.5 on a weight basis.
  • Example 1 and Examples 4 to 7 each containing at least one saccharide surfactant and at least one sorbitan surfactant exhibited excellent results in both high temperature stability and acceleration stability.
  • Example 1 the result of Fig. 1 shows that even after storage at 45 ⁇ for 2 weeks after the preparation, no separation of the water phase and oil phase occurs, and it is visually confirmed that it is very stable as compared with Comparative Examples 1 to 5 I could.
  • FIG. 2 when the cream stabilized in the water-in-oil type was applied onto the skin in the composition of Example 1, it was confirmed that the powder particles were uniformly dispersed without any lumps.
  • Example 4 and Example 5 in which two kinds of sugar-based surfactants were used were compared among Examples, when the content of cetearyl alcohol * cetearyl glucoside was higher than that of Example 4 , It was expected that the hardness of the formulation was found to be the highest, resulting in a higher possibility that the long-term stability was more excellent. This results from the fact that the fatty alcohol contained in the cetearyl alcohol * cetearyl glucoside increases the hardness by forming a liquid crystal around the O / W interface film formed by cetearyl glucoside while keeping the interface film harder .
  • Comparative Example 4 using only a saccharide surfactant showed good stability in acceleration, but showed normal stability at a high temperature, indicating that the stability at high temperature was weaker than the acceleration stability there was.
  • the high temperature stability and the acceleration stability were similar, but the comparative example 4 tended to be more influenced when exposed to high temperature.
  • Comparative Example 1 and Comparative Example 2 using the anionic surfactant instead of the sorbitan surfactant did not form a stable formulation as shown in Table 4 and FIG. When exposed to 45 ° C for two weeks, the powder disintegrated as the water separated.
  • Comparative Example 3 using PEG-100 stearate as a PEG surfactant instead of a sorbitan surfactant the formulation was formed as shown in Table 4 and FIG. 1, but the stability at a high temperature and the stability in acceleration were poor, .

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Abstract

The present invention relates to an oil-in-water cosmetic composition, wherein high-content calamine is stabilized in an inner phase by using a mixture of a sorbitan-based surfactant and a sugar-based surfactant. The present invention also relates to a use of a mixture of a sorbitan-based surfactant and a sugar-based surfactant as an inner phase stabilizer in the preparation of an oil-in-water cosmetic composition containing high-content calamine in an inner phase. The present invention also relates to a method for stabilizing high-content calamine in an inner phase of an oil-in-water cosmetic composition. Furthermore, the present invention relates to a method for maximizing functional activity of calamine by applying, to the skin, the oil-in-water cosmetic composition containing a high-content calamine in an inner phase according to the present invention.

Description

칼라민 고함량 내상 안정화 수중유형 화장료 조성물Colorant Amount Amount Internal stabilization Underwater type Cosmetic composition
관련 출원의 상호참조Cross reference of related application
본원은 한국 특허출원 제10-2017-0156407호(출원일: 2017년 11월 22일)에 대한 우선권을 주장하며, 상기 한국출원 명세서는 참조를 위해 전체로서 본원에 포함된다.The present application claims priority to Korean Patent Application No. 10-2017-0156407 filed on Nov. 22, 2017, the Korean application specification being incorporated herein by reference in its entirety.
기술 분야Technical field
본 발명은 소르비탄(Sorbitan)계 계면활성제 및 당류계 계면활성제를 혼합 사용하여, 고함량의 칼라민(Calamine)을 내상에 안정화한 수중유형 화장료 조성물에 관한 것이다. 또한, 본 발명은 내상에 고함량의 칼라민을 함유하는 수중유형 화장료 조성물의 제조에 있어서, 내상 안정화제로서 소르비탄계 계면활성제 및 당류계 계면활성제의 혼합물의 용도에 관한 것이다. 또한, 본 발명은 수중유형 화장료 조성물의 내상에 고함량 칼라민을 안정화하는 방법에 관한 것이다. 나아가, 본 발명은 본 발명에 따른 내상에 고함량의 칼라민이 안정화된 수중유형 화장료 조성물을 피부에 적용하여 칼라민의 기능적 활성을 극대화하는 방법에 관한 것이다.The present invention relates to an underwater type cosmetic composition in which a high content of calamine is stabilized in the inner phase by using a combination of a sorbitan surfactant and a sugar surfactant. The present invention also relates to the use of a mixture of a sorbitan surfactant and a saccharide surfactant as an internal stabilizer in the preparation of an underwater type cosmetic composition containing a high content of calamine in the interior. The present invention also relates to a method for stabilizing high-content calamine in the in-vivo type cosmetic composition. Furthermore, the present invention relates to a method for maximizing the functional activity of a calamine by applying a high-content, in-vivo calamine-stabilized underwater-type cosmetic composition according to the present invention to the skin.
칼라민(Calamine)은 산화아연과 0.5~1%의 산화철(Ⅲ)을 혼합하여 얻는 담홍색 고운 분말로, 칼라민에 포함된 산화아연은 소염 및 보호 작용을 지닌다. 따라서 칼라민은 연고, 살포제 등 피부 외용제에 함유되어 피부 질환 치료를 위한 보호제, 수렴제, 방부제로 사용된다. 또한 화장품 분야에서는 칼라민 로션 기제에 함유되어 여드름 피부 개선과 피부 진정 등의 목적으로 사용되고 있다.Calamine is a light pink fine powder obtained by mixing zinc oxide with 0.5 ~ 1% iron oxide (III). Zinc oxide contained in the calamine has an anti-inflammatory and protective action. Therefore, calamine is contained in external preparations for skin such as ointment and spraying agent, and is used as a protective agent for treating skin diseases, an astringent agent, and an antiseptic agent. In the field of cosmetics, it is contained in a calamine lotion base and is used for the purpose of improving acne skin and soothing the skin.
그러나 종래의 칼라민 화장품은 대부분 유중수형으로, 발림성이 뻑뻑하고 흡수력이 낮은 편이다. 또한 수중유형의 칼라민 화장료가 간혹 시도되고는 있으나 칼라민을 내상이 아닌 외상에 강제 분산하여 만드는 경우가 대부분으로, 이 경우 발림성은 좋아지나 흡수력은 떨어진다는 한계가 있다. 대한민국 등록특허 제10-1590803호는 칼라민을 함유하는 즉각미백 또는 안색개선용 화장료 조성물을 개시하고 있다. 하지만 이 특허에서도 효과를 얻을 수 있는 제형으로 수중유형보다는 유중수형을 채택하고 있다.However, most of the conventional calamine cosmetics are water-in-oil type, and are sobbing and absorbent. In addition, there is a limitation that the water-in-oil type colamine cosmetic is sometimes tried, but the calamine is forcedly dispersed in the trauma, not the inner cavity. Korean Patent No. 10-1590803 discloses a cosmetic composition for improving immediate whitening or complexion containing calamine. However, this patent also adopts a water-in-oil type rather than an underwater type as an effective formulation.
칼라민을 수중유형의 제형에 안정화하고 장기 안정성을 높이기 위한 주요 관건은 폴리머와 칼라민이 엉겨 입자로 석출되거나 폴리머가 겔화(gelling)되는 현상을 극복하는 것이다. 본 발명에서는 수중유형 칼라민 화장료 조성물 제조 시 칼라민과 폴리머가 직접 접촉하는 것을 막기 위해, 칼라민을 폴리머가 존재하는 외상과 분리시켜 내상에 안정화하고자 하였다. 그러한 방법으로서 칼라민에 소르비탄계 계면활성제 및 당류계 계면활성제를 함께 사용하는 방법을 고안해 냈으며, 이를 통해 수중유형 화장료의 내상에 고함량의 칼라민을 안정화시켜 장기 안정성을 확보하고, 화장료의 사용감 또한 개선할 수 있게 되었다.The key to stabilizing the calamine in water-in-oil formulations and enhancing its long-term stability is to overcome the phenomenon of precipitation of the polymer and calamine into the particles and gelling of the polymer. In the present invention, in order to prevent the direct contact between the calamine and the polymer when preparing the underwater type calamine cosmetic composition, the calamine was separated from the outer surface of the polymer and stabilized inward. As such a method, there has been devised a method of using a calorimine-based surfactant and a sugar-based surfactant together, thereby securing a long-term stability by stabilizing a high content of calamine in the inner phase of an underwater type cosmetic, It is also possible to improve.
[선행기술문헌][Prior Art Literature]
[특허문헌][Patent Literature]
(특허문헌 1) 1. 대한민국 등록특허 제10-1590803호(Patent Document 1) 1. Korean Patent No. 10-1590803
본 발명자들은 기존의 유중수형 칼라민 화장료보다 개선된 사용감을 얻기 위하여, 고함량의 칼라민이 수중유형에 안정화된 화장료를 제조하고자 하였다. 그러나 칼라민을 수중유형에 안정화시키는 과정에서 폴리머의 겔화 현상이 문제점으로 대두되었으며, 이를 해결하기 위해 폴리머와 칼라민을 서로 다른 상에 분산시키는 방법을 고안하였다.The present inventors tried to prepare a cosmetic stabilized with a high content of colorini in water type in order to obtain improved feeling than the conventional water-in-oil type colorin cosmetic. However, in the process of stabilizing the calamine in water, the gelation phenomenon of the polymer became a problem. To solve this problem, a method of dispersing the polymer and the calamine in different phases was devised.
즉, 종래의 방법처럼 칼라민을 외상인 수상에 강제적으로 분산하는 것이 아니라, 내상인 유상에 안정화시키는 방법으로서 소르비탄계 계면활성제 및 당류계 계면활성제를 일정 비율로 배합하여 함께 사용하면 이 문제를 해결할 수 있음을 발견하고 본 발명을 완성하게 되었다.That is, as a method of stabilizing the oil phase which is the inner phase, instead of forcibly dispersing the calamine into the traumatic water phase as in the conventional method, when a combination of the sorbitan surfactant and the sugar surfactant is used at a certain ratio and used together, The present invention has been completed.
따라서, 본 발명의 목적은 고함량 칼라민을 내상에 안정화한 수중유형 화장료 조성물을 제공하는 것이다.Accordingly, it is an object of the present invention to provide an underwater-type cosmetic composition which stabilizes a high-content coloramine in the interior.
상기 목적을 달성하기 위하여, 본 발명은 칼라민, 소르비탄계 계면활성제 및 당류계 계면활성제를 함유하여 칼라민을 내상에 안정화시킴으로써, 고함량 칼라민이 안정화된 수중유형 화장료 조성물을 제공한다.In order to achieve the above object, the present invention provides a water-in-oil cosmetic composition stabilized with a high content of calamine by stabilizing the calamine in the inner phase by containing a calamine, a sorbitan surfactant and a sugar-based surfactant.
또한, 본 발명은 내상에 고함량의 칼라민을 함유하는 수중유형 화장료 조성물의 제조에 있어서, 내상 안정화제로서 소르비탄계 계면활성제 및 당류계 계면활성제의 혼합물의 용도를 제공한다. 또한, 본 발명은 수중유형 화장료 조성물의 내상에 고함량 칼라민을 안정화하는 방법을 제공한다. 나아가, 본 발명은 본 발명에 따른 내상에 고함량의 칼라민이 안정화된 수중유형 화장료 조성물을 피부에 적용하여 칼라민의 기능적 활성을 극대화하는 방법을 제공한다.The present invention also provides the use of a mixture of a sorbitan surfactant and a saccharide surfactant as an internal stabilizer in the preparation of an underwater-type cosmetic composition containing a high content of calamine in the inner layer. The present invention also provides a method for stabilizing high-content calamine in the in-vivo type cosmetic composition. Further, the present invention provides a method for maximizing the functional activity of a calamine by applying a high-calorie-stabilized water-in-oil type cosmetic composition according to the present invention to the skin.
본 발명에 따른 화장료 조성물은 소르비탄계 계면활성제 및 당류계 계면활성제를 함께 사용함으로써 칼라민 함유 수중유 제형의 안정도 및 장기 안정도를 높일 수 있다. 또한 고함량 칼라민을 수중유형의 내상에 안정화할 수 있게 됨으로써, 뻑뻑한 발림성 등 좋지 않은 사용감을 개선하고 피부 흡수력을 높일 수 있다.The cosmetic composition according to the present invention can increase the stability and long-term stability of a calamine-containing oil-in-water preparation by using a combination of a sorbitan surfactant and a sugar surfactant. In addition, since the high-content calamine can be stabilized to the inner phase of the water type, it is possible to improve the feeling of bad feeling such as stiffness and the skin absorbency.
도 1은 실시예 1 및 비교예 1 내지 5를 제조 후 2주 동안 45℃에서 보관한 후 수상과 유상의 분리 정도를 관찰하기 위해 조성물 외관을 촬영한 사진이다.FIG. 1 is a photograph of the appearance of a composition for observing the degree of separation between water phase and oil phase after storing Example 1 and Comparative Examples 1 to 5 at 45.degree. C. for 2 weeks after production.
도 2는 실시예 1의 조성으로 수중유형에 안정화한 크림상의 외관을 촬영한 사진이다. 도 2의 오른쪽 하단 작은 사진은 해당 크림을 피부에 펴 바른 모습으로, 파우더 입자가 전혀 뭉침 없이 고르게 분산되어 있는 것을 확인할 수 있다.Fig. 2 is a photograph of the appearance of a cream-like appearance stabilized in an underwater type with the composition of Example 1. Fig. In the lower right side of Fig. 2, the cream is spread on the skin, and powder particles are uniformly dispersed without clumping at all.
본 발명은 칼라민, 소르비탄계 계면활성제 및 당류계 계면활성제를 함유하여 고함량 칼라민을 내상에 안정화한 수중유형 화장료 조성물에 관한 것이다.The present invention relates to an underwater type cosmetic composition containing a calamine, a sorbitan surfactant and a sugar surfactant and stabilizing a high-content calamine in the inner phase.
이하, 본 발명을 보다 구체적으로 설명한다.Hereinafter, the present invention will be described more specifically.
칼라민Calamine
화장료에서 효능 성분으로 함유되는 칼라민은 담홍색을 띠는 고운 분말 원료로서, 여드름 피부 개선과 피부 진정의 목적으로 주로 사용된다. 또한 유중수형 화장료에 포함되어 미백 효과와 보습 효과를 나타내는 것으로도 알려져 있다.Calamine, which is contained as an effective ingredient in cosmetics, is a fine powder with a light pink color. It is mainly used for improving acne skin and soothing skin. It is also known to exhibit whitening effect and moisturizing effect by being included in a water-in-oil type cosmetic material.
본 발명에서는 이러한 효능을 지닌 칼라민을 고함량 함유하되, 유중수형이 아닌 수중유형의 내상에 안정화한 화장료 조성물을 제공한다.The present invention provides a cosmetic composition which contains a high content of calamine having such an effect and which is stabilized in the in-water type, which is not a water-in-oil type.
본 발명에 따른 화장료 조성물에서 상기 칼라민은 조성물 총 중량에 대하여 0.01 내지 15 중량% 포함할 수 있고, 바람직하게는 5 내지 15 중량% 포함할 수 있다. 상기 칼라민이 15 중량%를 초과할 경우 분산 안정도가 저하될 수 있으며, 상기 칼라민이 0.01 중량% 미만일 경우 칼라민에 의한 피부 영향 효과가 미미할 수 있다.In the cosmetic composition according to the present invention, the calamine may be contained in an amount of 0.01 to 15% by weight, preferably 5 to 15% by weight based on the total weight of the composition. If the content of the columbium is more than 15% by weight, the dispersion stability may be lowered. If the content of the columbium is less than 0.01% by weight, the effect of the skin due to the coloramine may be insignificant.
본 발명에 따른 화장료 조성물에서 상기 칼라민은 상업적으로 시판되는 원료를 사용할 수 있고, 칼라민을 구성하는 성분의 배합 비율을 조절하여 통상의 방법으로 제조 가능한 변형된 칼라민을 사용할 수도 있다.In the cosmetic composition according to the present invention, the above-mentioned calamine may be a commercially available raw material, or a modified calamine which can be prepared by a conventional method by controlling the compounding ratio of components constituting the calamine.
당류계 계면활성제 및 소르비탄계 계면활성제Sugar-based surfactants and sorbitan-based surfactants
본 발명에서는 상기 칼라민을 수중유형의 내상에 안정화하기 위해 비이온성 계면활성제를 사용하며, 비이온성 계면활성제 중에서도 당류계 계면활성제 1종 이상 및 소르비탄계 계면활성제 1종 이상을 함께 사용한다.In the present invention, a nonionic surfactant is used to stabilize the calamine in the water-in-oil type, and at least one of a sugar surfactant and at least one sorbitan surfactant is used together with the nonionic surfactant.
본 발명에 따른 화장료 조성물에서 상기 당류계 계면활성제는 알킬폴리글리코시드(Alkyl polyglycoside, APGs)류 계면활성제, 당에스테르(Sugar ester)류 계면활성제, 또는 이들의 혼합물을 지칭한다.In the cosmetic composition according to the present invention, the sugar type surfactant refers to an alkyl polyglycoside (APGs) type surfactant, a sugar ester type surfactant, or a mixture thereof.
상기 알킬폴리글리코시드류 계면활성제에서 알킬폴리글리코시드는 하기 화학식 1로 표현되는 일반적인 알킬폴리글리코시드를 말한다. 또한 본 발명에서 상기 알킬폴리글리코시드류 계면활성제는 하기 화학식 1로 표현되는 알킬폴리글리코시드와 지방알코올의 혼합물을 포함해 지칭하는 것일 수 있다.The alkylpolyglycosides in the alkylpolyglycoside surfactants refer to general alkylpolyglycosides represented by the following general formula (1). In the present invention, the alkylpolyglycoside surfactant may include a mixture of an alkyl polyglycoside represented by the following formula (1) and a fatty alcohol.
[화학식 1][Chemical Formula 1]
Figure PCTKR2018014352-appb-I000001
Figure PCTKR2018014352-appb-I000001
상기 당에스테르류 계면활성제에서 당에스테르는 주로 당 지방산 에스테르로서, 글루코스와 C10-C30 지방산, 바람직하게는 C12-C26의 지방산이 에스테르 결합한 물질을 말한다. 또한 본 발명에서 상기 당에스테르류 계면활성제는 일반적인 당 지방산 에스테르와 함께, 당 및 다른 물질의 축합 반응물과 지방산이 결합하여 생성된 에스테르 화합물도 포함한다.In the sugar ester surfactants, the sugar ester is mainly a saccharide fatty acid ester, and refers to a substance in which a fatty acid of C10-C30 fatty acid, preferably C12-C26, is ester-bonded to glucose. In addition, in the present invention, the sugar ester surfactant includes an ester compound produced by bonding a fatty acid with a condensation reaction product of sugar and other substances together with a common sugar fatty acid ester.
바람직하게는, 본 발명에 따른 화장료 조성물에서 상기 알킬폴리글리코시드류 계면활성제는 C6-C30의 고급 알코올과 C10-C30 글루코시드 유도체의 혼합물로 이루어진 계면활성제 중에서 선택되는 1종 이상일 수 있다. 보다 상세하게는 C14-22알코올*C12-20알킬글루코시드(C14-22 Alcohols and C12-20 Alkyl Glucoside), 세테아릴알코올*세테아릴글루코시드(Cetearyl Alcohol and Cetearyl Glucoside), 베헤닐알코올*아라키딜글루코시드*아라키딜알코올(Behenyl Alcohol and Arachidyl Alcohol and Arachidyl Glucoside), 세테아릴알코올*코코글루코시드(Cetearyl Alcohol and Coco-Glucoside)로 이루어진 군에서 선택되는 1종 이상일 수 있다.Preferably, in the cosmetic composition according to the present invention, the alkyl polyglycoside surfactant may be at least one selected from surfactants composed of a mixture of C6-C30 higher alcohol and C10-C30 glucoside derivative. More particularly, the present invention relates to a method for producing a C14-22 alcohol * C12-20 alkyl glucoside, Cetearyl Alcohol and Cetearyl Glucoside, a behenyl alcohol * It may be at least one selected from the group consisting of arachidyl glucoside, behenyl alcohol and arachidyl alcohol and arachidyl glucoside, cetearyl alcohol and coco-glucoside.
또한 바람직하게는, 본 발명에 따른 화장료 조성물에서 상기 당에스테르류 계면활성제는 폴리글리세릴-3메칠글루코스디스테아레이트(Polyglyceryl-3 Methylglucose Distearate)일 수 있다.Also, preferably, in the cosmetic composition according to the present invention, the sugar ester surfactant may be polyglyceryl-3 methylglucose distearate.
더욱 바람직하게는, 본 발명에 따른 화장료 조성물에서 상기 당류계 계면활성제는 상기 알킬폴리글리코시드류 계면활성제로서 세테아릴알코올*세테아릴글루코시드(Cetearyl Alcohol*Cetearyl Glucoside)를 단독으로 사용하거나, 또는 상기 세테아릴알코올*세테아릴글루코시드와 상기 당에스테르류 계면활성제로서 상기 폴리글리세릴-3메칠글루코스디스테아레이트(Polyglyceryl-3 Methylglucose Distearate)를 혼합하여 함께 사용할 수 있다.More preferably, in the cosmetic composition according to the present invention, the above-mentioned saccharide-type surfactant may be prepared by using Cetearyl Alcohol * Cetearyl Glucoside alone as the alkylpolyglycoside surfactant, Alternatively, the polyglyceryl-3 methylglucose distearate may be used together with the above-mentioned cetearyl alcohol * cetearyl glucoside and the sugar ester surfactant.
본 발명에 사용되는 상기 당류계 계면활성제는 수중유(O/W) 유화 입자를 안정화하는 역할을 한다. 특히, 본 발명에 사용될 수 있는 상기 세테아릴알코올*세테아릴글루코시드(Cetearyl Alcohol*Cetearyl Glucoside)는 세타아릴알코올이 포함되어 지방알코올의 함량이 더 높은 계면활성제로서, 여기에 포함된 지방알코올은 세테아릴글루코시드가 형성한 O/W 계면막 주위에 액정을 형성하면서 계면막을 더 단단하게 유지시키는 역할을 한다. 이로 인해 가혹한 조건에서나 장기간 보관 시에도 유화 안정도를 우수하게 유지시켜줌으로써, 본 발명에서 칼라민이 응집되거나 분리되는 것을 방지하는 중요한 성분이 될 수 있다.The sugar-based surfactant used in the present invention serves to stabilize oil-in-water (O / W) emulsified particles. In particular, the cetearyl alcohol * Cetearyl Glucoside, which can be used in the present invention, is a surfactant having a higher content of fatty alcohols including cetearyl alcohol, and the fatty alcohol Plays a role of keeping the interface film harder while forming liquid crystals around the O / W interface film formed by cetearyl glucoside. Therefore, it is possible to maintain the emulsion stability even under harsh conditions or for a long period of storage, and thus it can be an important component for preventing the aggregation or separation of chromamine in the present invention.
본 발명에 따른 화장료 조성물에서 상기 당류계 계면활성제는 조성물 총 중량에 대하여 0.1 내지 8 중량% 포함할 수 있고, 바람직하게는 1 내지 5 중량% 포함할 수 있다. 상기 당류계 계면활성제가 8 중량%를 초과할 경우 제형이 형성되지 않을 수 있으며, 0.1 중량% 미만일 경우 계면활성제로서의 역할이 미미하다.In the cosmetic composition according to the present invention, the saccharide-based surfactant may be contained in an amount of 0.1 to 8% by weight, preferably 1 to 5% by weight, based on the total weight of the composition. If the amount of the sugar-based surfactant exceeds 8% by weight, the formulation may not be formed, and if it is less than 0.1% by weight, the surfactant may have a small role.
본 발명에 따른 화장료 조성물에서 소르비탄계 계면활성제는 소르비탄 에스테르(Sorbitan Ester), 그리고 소르비탄 에스테르와 산화에틸렌의 부가중합체를 포함한다. 소르비탄 에스테르는 통상 당류계 계면활성제로 분류되기도 하나, 본 발명에서는 소르비탄 에스테르 및/또는 이의 중합체 성분이 본 발명에 따른 화장료 조성물의 제형 안정도에 큰 영향을 끼치므로 이를 중요히 여겨 따로 분류하였다.In the cosmetic composition according to the present invention, the sorbitan surfactant includes a sorbitan ester and an addition polymer of sorbitan ester and ethylene oxide. The sorbitan esters are usually classified as sugar type surfactants, but the sorbitan esters and / or the polymer components of the sorbitan esters are classified as important because they greatly affect the formulation stability of the cosmetic composition according to the present invention.
본 발명에 따른 화장료 조성물에서 상기 소르비탄계 계면활성제는 소르비탄 지방산 에스테르를 사용하는 것이 바람직하며, 소르비탄올리베이트(Sorbitan Olivate), 소르비탄스테아레이트(Sorbitan Stearate), 소르비탄이소스테아레이트(Sorbitan Isostearate), 소르비탄트리스테아레이트(Sorbitan Tristearate), 소르비탄세스퀴스테아레이트(Sorbitan Sesquistearate), 소르비탄팔미테이트(Sorbitan Palmitate), 소르비탄라우레이트(Sorbitan Laurate), 소르비탄올리에이트(Sorbitan Oleate), 소르비탄세스퀴올리에이트(Sorbitan Sesquioleate), 소르비탄트리올리에이트(Sorbitan Trioleate), 소르비탄스테아레이트/소르비틸라우레이트(Sorbitan Stearate and Sorbityl Laurate), 폴리소르베이트 20(Polysorbate 20), 폴리소르베이트 40, 폴리소르베이트 60, 폴리소르베이트 65, 폴리소르베이트 80, 및 폴리소르베이트 85로 이루어진 군에서 1종 이상을 포함할 수 있다. In the cosmetic composition according to the present invention, the sorbitan surfactant is preferably a sorbitan fatty acid ester, and it is preferable to use a sorbitan fatty acid ester such as sorbitan olivate, sorbitan stearate, sorbitan isostearate Sorbitan isostearate, sorbitan tristearate, sorbitan sesquistearate, sorbitan palmitate, sorbitan laurate, sorbitan oleate, ), Sorbitan sesquioleate, sorbitan trioleate, sorbitan stearate and sorbitol laurate, polysorbate 20, poly < RTI ID = 0.0 > Consisting of sorbate 40, polysorbate 60, polysorbate 65, polysorbate 80, and polysorbate 85 In may include more than one species.
본 발명에 사용되는 상기 소르비탄계 계면활성제는 수중유형의 내상에 칼라민 파우더가 잘 분산되도록 분산성을 증대시키는 역할을 한다. 특히, 소르비탄 에스테르에 계면활성력이 매우 우수한 폴리에틸렌글리콜(Polyethylene Glycol, PEG)을 접목한 계면활성제인 폴리소르베이트(Polysorbate)를 조합하여 사용하면, 고함량의 칼라민을 수중유형의 내상에 안정화하는 데 있어 매우 효과적일 수 있다.The sorbitan surfactant used in the present invention has the function of increasing the dispersibility so that the calamine powder is well dispersed in the water-in-oil type. Particularly, when a combination of sorbitan ester and polysorbate, which is a surface active agent grafted with polyethylene glycol (PEG) having a very high surfactant activity, is used in combination, a high content of calamine is stabilized in the in- It can be very effective in doing so.
본 발명에 따른 화장료 조성물에서 상기 소르비탄계 계면활성제는 조성물 총 중량에 대하여 0.01 내지 5 중량% 포함할 수 있고, 바람직하게는 0.5 내지 4 중량% 포함할 수 있다. 상기 소르비탄계 계면활성제가 5 중량%를 초과할 경우 제형 형성에 방해될 수 있으며, 0.01 중량% 미만일 경우에는 분산성 개선 능력을 기대하기 어렵다.In the cosmetic composition according to the present invention, the sorbitan surfactant may be contained in an amount of 0.01 to 5% by weight, preferably 0.5 to 4% by weight based on the total weight of the composition. If the content of the sorbitan surfactant is more than 5% by weight, it may interfere with the formation of the formulations, and if it is less than 0.01% by weight, it is difficult to expect the dispersibility improving ability.
본 발명에 따른 화장료 조성물에서 상기 당류계 계면활성제와 상기 소르비탄계 계면활성제는 각 1종 이상이 함께 사용되는 것이 바람직하며, 당류계 계면활성제만 사용하거나 소르비탄계 계면활성제만 사용하는 경우 조성물의 수중유형 제형이 잘 형성되지 않거나 안정도가 현저히 떨어질 수 있다. 가장 바람직하게는 상기 당류계 계면활성제 및 상기 소르비탄계 계면활성제의 혼합비율이 중량 기준으로 2.5 : 0.6 내지 2.5일 때 우수한 제형 안정성 및 장기 안정성을 나타낼 수 있다.In the cosmetic composition according to the present invention, it is preferable that one or more of the above-mentioned saccharide surfactant and the above-mentioned sorbitan surfactant are used together, and when only a saccharide surfactant is used or only a sorbitan surfactant is used, The underwater type formulation may not be well formed or the stability may be significantly deteriorated. Most preferably, when the mixing ratio of the saccharide-based surfactant and the sorbitan-based surfactant is 2.5: 0.6 to 2.5 based on the weight, excellent formulation stability and long-term stability can be exhibited.
또한 본 발명에 따른 화장료 조성물에서 상기 소르비탄계 계면활성제 대신 다른 비이온성 계면활성제를 사용하거나, 음이온성 계면활성제를 사용하는 것은 바람직하지 않을 수 있다. 예를 들어 범용적으로 사용되는 비이온성 계면활성제인 피이지-100 스테아레이트(PEG-100 Stearate)나 글리세릴모노스테아레이트(Glyceryl MonoStearate)를 사용하는 경우, 또는 음이온성 계면활성제인 글리세릴스테아레이트시트레이트(Glyceryl Stearate Citrate)나 포타슘세틸포스페이트(Potassium Cetyl Phosphate) 등을 사용하는 경우, 당류계 계면활성제 및 소르비탄계 계면활성제의 혼합 사용 없이 이들만으로는 수중유형의 내상에 칼라민을 안정화하기 어려우며, 제조 시 제형이 형성되지 않고 바로 분리되거나 제형이 형성되더라도 장기 안정도를 떨어뜨릴 수 있다.It may be undesirable to use other nonionic surfactants instead of the sorbitan surfactants or to use anionic surfactants in the cosmetic composition according to the present invention. For example, when using PEG-100 Stearate or Glyceryl MonoStearate, which is a non-ionic surfactant commonly used, or when an anionic surfactant such as glyceryl stearate In the case of using Glyceryl Stearate Citrate or Potassium Cetyl Phosphate, it is difficult to stabilize the calamine in the water-in-oil type alone without mixing the sugar surfactant and the sorbitan surfactant, The long-term stability may be lowered even if the formulation is not formed at the time of manufacture and is immediately separated or the formulation is formed.
그 밖의 성분Other components
본 발명에 따른 화장료 조성물은 칼라민과 상기 당류계 및 소르비탄계 계면활성제 외에도 오일, 폴리올, 점증제 및 물 등을 더 포함할 수 있다.The cosmetic composition according to the present invention may further comprise an oil, a polyol, an aging agent, water, etc., in addition to the calamine and the saccharide-based or sorbitan-based surfactant.
본 발명에 따른 화장료 조성물에서 오일은 적정한 보습력을 부여하기 위해 예를 들어 에스테르계, 하이드로카본(hydrocarbon)계 오일을 조성물 총 중량에 대하여 10 중량% 내외로 포함할 수 있다. 또한 폴리올을 조성물 총 중량에 대하여 5 내지 15 중량% 포함할 수 있다. In the cosmetic composition according to the present invention, the oil may contain, for example, an ester-based or hydrocarbon-based oil in an amount of about 10% by weight or more based on the total weight of the composition in order to impart adequate moisture. Also, the polyol may be contained in an amount of 5 to 15% by weight based on the total weight of the composition.
또한 점증제로는 예를 들어 하이드록시에칠아크릴레이트/소듐아크릴로일디메칠타우레이트코폴리머(Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer), 암모늄아크릴로일디메칠타우레이트/VP코폴리머(Ammonium Acryloyldimethyltaurate/VP Copolymer), 폴리아크릴레이트크로스폴리머-6(Polyacrylate Crosspolymer-6), 폴리아크릴레이트(Polyacrylate-13), 또는 소듐폴리아크릴레이트(Sodium Poylacrylate)와 같은 폴리아크릴레이트류 등을 사용할 수 있으며, 조성물 총 중랑에 대하여 0.1 내지 3 중량% 포함할 수 있다.Examples of the thickening agent include hydroxyethyl methacrylate / sodium acryloyldimethyl taurate copolymer, ammonium acryloyldimethyltaurate / VP copolymer, and the like. Polyacrylates such as Polyacrylate Crosspolymer-6, Polyacrylate-13, and Sodium Poylacrylate may be used. The composition may be used in a total amount of the composition 0.1 to 3 % By weight.
본 발명에 따른 화장료 조성물에서 점증제로 폴리아크릴레이트류를 사용할 경우, 카보머 계열의 점증제를 사용하는 것보다 수중유형의 제형 안정도에 더 유리할 수 있다. 수중유형에서 카보머 계열의 점증제를 사용할 경우, 전하의 영향을 쉽게 받아 칼라민과 같은 파우더와 더 쉽게 엉겨버리는 현상이 발생하여 품질을 떨어뜨릴 수 있기 때문이다.When polyacrylates are used as an incremental agent in the cosmetic composition according to the present invention, it may be more advantageous in formulation stability of an underwater type than using a carbomer-based thickener. When using a carbomer-based thickener in an underwater type, it is easily influenced by electric charges and becomes more easily entangled with a powder such as a calamine, which may deteriorate the quality.
또한 본 발명에 따른 화장료 조성물은 상기 성분 이외에도 일반적으로 화장료 제조 시 통상적으로 사용되는 보습제, 색소, 향, 방부제 및 기타 첨가제 중에서 선택된 1종 이상을 추가로 포함할 수 있다.In addition, the cosmetic composition according to the present invention may further include at least one selected from the group consisting of moisturizers, pigments, fragrances, preservatives and other additives commonly used in cosmetics, in addition to the above components.
본 발명에 따른 수중유형 화장료 조성물에서, 상기 수중유형은 oil-in-water(O/W) 형태로 외상(연속상)이 수상, 내상(비연속상)이 유상인 유화 제형이며, 주요 피부 효능 성분인 칼라민은 내상에 함유되도록 제조된다.In the underwater-type cosmetic composition according to the present invention, the water-in-oil type is an oil-in-water (O / W) type emulsion form in which the external phase (continuous phase) The colocalimin is prepared to be contained in the intestine.
예를 들어, 본 발명에 따른 수중유형 화장료 조성물은 수상 성분과 유상 성분을 각각 가온 용해한 다음, 수상 파트에 유상 파트를 넣고 유화하되, 칼라민은 유상 성분에 포함하여 분산한다. 그리고, 상기 유화된 내용물을 냉각한 후 점증제를 추가 및 분산하는 과정을 거쳐 제조될 수 있다. For example, the water-in-oil type cosmetic composition according to the present invention is prepared by dissolving a water-based component and an oil-based component at room temperature, emulsifying the oil-based part in an aqueous phase, and dispersing it in an oil-based component. Then, the emulsified contents may be cooled, and then the thickening agent may be added and dispersed.
상기의 방법으로 제조된 본 발명에 따른 수중유형 화장료 조성물은 45℃의 고온 조건 및 9,000rpm의 고속 혼합 시에도 입자가 석출되거나 제형이 분리되지 않으며, 12개월 이상 장기 안정도를 유지할 수 있다.The water-in-oil type cosmetic composition according to the present invention produced by the above-mentioned method can keep long-term stability for 12 months or longer without precipitation of particles or separation of formulations even at high temperature of 45 ° C and high-speed mixing at 9,000 rpm.
또한 상기 방법에 따라 안정화된 본 발명의 화장료 조성물은 발림성 등의 사용감을 개선하고 피부 흡수력을 향상시킬 수 있다.In addition, the cosmetic composition of the present invention stabilized in accordance with the above method can improve feeling of use such as spreadability and improve skin absorbency.
본 발명에 따른 수중유형 화장료 조성물은 특별한 제한은 없으나, 에센스, 로션, 크림, 밤 형태로 제형화되어 피부 또는 점막에 도포되거나 분무될 수 있으며, 보습, 미백, 단기적 피부톤 개선 및 보정, 트러블케어, 진정, 또는 민감성 피부 개선 등을 위한 화장료에 이용될 수 있다.The underwater type cosmetic composition according to the present invention may be formulated into an essence, lotion, cream, or night form to be applied or sprayed on the skin or mucous membranes, without any particular limitation, and may be moisturized, whitened, Sedative, or sensitive skin, and the like.
이하, 실시예 및 비교예를 통해 본 발명을 더욱 상세히 설명한다. 그러나, 하기 실시예 및 비교예는 본 발명의 이해를 돕기 위한 것일 뿐, 본 발명에 따른 실시예들은 여러 가지 다른 형태로 변형될 수 있으며, 본 발명의 범위가 이에 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail by way of examples and comparative examples. However, it should be understood that the following examples and comparative examples are provided only for the understanding of the present invention, and the embodiments according to the present invention may be modified in various forms, and the scope of the present invention is not limited thereto.
[실시예 및 비교예: 수중유형 화장료 조성물의 제조][Examples and Comparative Examples: Preparation of an underwater type cosmetic composition]
하기 표 1 및 표 2에 기재된 각 성분과 함량에 따라, 다음의 제조방법으로, 실시예 1~7 및 비교예 1~5의 수중유형 화장료 조성물을 제조하였다.The water-in-oil type cosmetic compositions of Examples 1 to 7 and Comparative Examples 1 to 5 were prepared by the following production methods according to the contents and contents shown in Tables 1 and 2 below.
제조 시 칼라민은 제품명 "Calamine((주)주환 바이오 셀 제조)"을 사용하였고, 당류계 계면활성제는 세테아릴알코올*세테아릴글루코시드(Montanov 68, 프랑스의 Seppic사 제조) 및/또는 폴리글리세릴-3메칠글루코스디스테아레이트(Tego care 450, Evonik사 제조)를 실시예에 사용하였으며, 소르비탄계 계면활성제는 소르비탄올리베이트(Olivem 1000, B&T사 제조) 및/또는 폴리소르베이트 60(TWEEN #60 V, CRODA사 제조)을 사용하였다.Calamin (manufactured by Jufa Biocell Co., Ltd.) was used as the calamine, and cetearyl alcohol * cetearyl glucoside (Montanov 68, Seppic Co., France) and / or Polyglyceryl-3 methylglucoside distearate (Tego care 450, manufactured by Evonik) was used in the examples. The sorbitan surfactant was sorbitan olivate (Olivem 1000, manufactured by B & T) and / or polysorbate 60 (TWEEN # 60 V, manufactured by CRODA) was used.
제조방법Manufacturing method
하기 표 1 및 표 2에 따라 원료를 계량한 후,After weighing the raw materials according to the following Tables 1 and 2,
(1) 정제수와 폴리올 등의 수상 성분을 비커에 섞고 75℃ 이상 가온 용해한다.(1) Mix the water components such as purified water and polyol into a beaker and dissolve at a temperature of 75 ° C or higher.
(2) 오일과 계면활성제 등의 유상 성분을 75℃ 이상 가온 용해한다.(2) Dissolve the oily components such as oil and surfactant at over 75 ℃.
(3) 칼라민을 수상 파트가 아닌, 유상 파트에 넣어 분산한다.(3) The calamine is dispersed in the oil-based part, not in the water-based part.
(4) 수상 파트에 유상 파트를 넣고 호모믹싱하여 유화한다.(4) Put the oil part in the water part and emulsify by homomixing.
(5) (4)에서 유화된 내용물을 일정 시간 동안 식힌 후 재분산한다. 점도가 일정 이상 형성된 후 전단(shear)을 가하면, 칼라민의 분산이 더 용이하다.(5) The emulsified contents in (4) are cooled for a certain period of time and then redispersed. When shear is applied after the viscosity is formed above a certain level, dispersion of the calamine is easier.
(6) 점증제를 추가하여 호모분산한다. (6) Homogenous addition by adding thickener.
성분ingredient 실시예 1Example 1 실시예 2Example 2 실시예 3Example 3 실시예 4Example 4 실시예 5Example 5 실시예 6Example 6 실시예 7Example 7
유상Paid 효능 성분Efficacy component CalamineCalamine 55 1010 1515 55 55 55 1010
계면활성제Surfactants Cetearyl Alcohol*Cetearyl Glucoside Cetearyl Alcohol * Cetearyl Glucoside 2.52.5 2.52.5 2.52.5 1One 22 2.52.5 2.52.5
Polyglyceryl-3 Methylglucose DistearatePolyglyceryl-3 Methylglucose Distearate 00 00 00 1.51.5 0.50.5 00 00
Sorbitan OlivateSorbitan Olivate 0.60.6 1One 1.51.5 0.60.6 0.60.6 00 1One
Polysorbate 60Polysorbate 60 00 00 00 00 00 0.60.6 1.51.5
Glyceryl Stearate CitrateGlyceryl Stearate Citrate 00 00 00 00 00 00 00
Potassium Cetyl PhosphatePotassium Cetyl Phosphate 00 00 00 00 00 00 00
PEG-100 StearatePEG-100 Stearate 00 00 00 00 00 00 00
오일oil 스쿠알란Squalane 44 44 44 44 44 44 44
Dicaprylyl CarbonateDicaprylyl Carbonate 55 55 55 55 55 55 55
수상Awards 폴리올Polyol PropanediolPropanediol 44 44 44 44 44 44 44
GlycerinGlycerin 33 33 33 33 33 33 33
물water 정제수Purified water to 100to 100 to 100to 100 to 100to 100 to 100to 100 to 100to 100 to 100to 100 to 100to 100
점증제Incrementer Hydroxyethyl Acrylate /Sodium Acryloyldimethyl Taurate CopolymerHydroxyethyl Acrylate / Sodium Acryloyldimethyl Taurate Copolymer 1One 1One 1One 1One 1One 1One 1One
성분ingredient 비교예 1Comparative Example 1 비교예 2Comparative Example 2 비교예 3Comparative Example 3 비교예 4Comparative Example 4 비교예 5Comparative Example 5
유상Paid 효능 성분Efficacy component CalamineCalamine 55 55 55 55 55
계면활성제Surfactants Cetearyl Alcohol*Cetearyl Glucoside Cetearyl Alcohol * Cetearyl Glucoside 2.52.5 2.52.5 2.52.5 3.13.1 00
Polyglyceryl-3 Methylglucose DistearatePolyglyceryl-3 Methylglucose Distearate 00 00 00 00 00
Sorbitan OlivateSorbitan Olivate 00 00 00 00 3.13.1
Polysorbate 60Polysorbate 60 00 00 00 00 00
Glyceryl Stearate CitrateGlyceryl Stearate Citrate 0.60.6 00 00 00 00
Potassium Cetyl PhosphatePotassium Cetyl Phosphate 00 0.60.6 00 00 00
PEG-100 StearatePEG-100 Stearate 00 00 0.60.6 00 00
오일oil 스쿠알란Squalane 44 44 44 44 44
Dicaprylyl CarbonateDicaprylyl Carbonate 55 55 55 55 55
수상Awards 폴리올Polyol PropanediolPropanediol 44 44 44 44 44
GlycerinGlycerin 33 33 33 33 33
물water 정제수Purified water to 100to 100 to 100to 100 to 100to 100 to 100to 100 to 100to 100
점증제Incrementer Hydroxyethyl Acrylate /Sodium Acryloyldimethyl Taurate CopolymerHydroxyethyl Acrylate / Sodium Acryloyldimethyl Taurate Copolymer 1One 1One 1One 1One 1One
[시험예 1: 유화 안정도 평가][Test Example 1: Evaluation of emulsion stability]
상기 실시예 1 내지 7 및 비교예 1 내지 5를 제조 후 2주 동안 45℃에서 보관한 후 수상과 유상의 분리 정도를 육안으로 관찰하여 제형 형성 안정도 및 고온 안정도를 평가하였다.The above Examples 1 to 7 and Comparative Examples 1 to 5 were stored at 45 캜 for 2 weeks after the preparation, and the degree of separation of the water phase and the oil phase was visually observed to evaluate the stability of formulation stability and high temperature stability.
그 결과는 도 1 및 하기 표 3과 표 4에 나타내었다. The results are shown in Fig. 1 and Tables 3 and 4 below.
[시험예 2: 가속 안정도 평가][Test Example 2: Evaluation of acceleration stability]
상기 실시예 1 내지 7 및 비교예 1 내지 5를 저온항온기(Low temp. Incubator) LTI-1001SD(EYELA 사의 제품명)를 이용하여 -15℃ 내지 45℃, 24hrs 사이클에서, 제형 분리 정도 및 파우더 뭉침 정도를 관찰하여 제형의 가속 안정도를 평가하였다.The results of Examples 1 to 7 and Comparative Examples 1 to 5 were evaluated using a low temperature incubator LTI-1001SD (product name of EYELA) at a temperature of -15 DEG C to 45 DEG C for 24 hours, And the accelerated stability of the formulation was evaluated.
그 결과는 하기 표 3과 표 4에 나타내었다.The results are shown in Tables 3 and 4 below.
실시예 1Example 1 실시예 2Example 2 실시예 3Example 3 실시예 4Example 4 실시예 5Example 5 실시예 6Example 6 실시예 7Example 7
안정도(45℃)Stability (45 ℃) ○○ ○○ ○○ ○○ ○○ ○○ ○○
가속안정도Acceleration stability ○○ ○○ ○○ ○○ ○○ ○○ ○○
비교예 1Comparative Example 1 비교예 2Comparative Example 2 비교예 3Comparative Example 3 비교예 4Comparative Example 4 비교예 5Comparative Example 5
안정도(45℃)Stability (45 ℃) XX XX △△ △△ XX
가속안정도Acceleration stability XX XX △△ ○○ XX
* ○: 양호, △: 보통, X: 분리*: Good,: Fair: Normal, X: Separation
상기 표 3에서 확인할 수 있는 바와 같이, 칼라민을 5 내지 15 중량%로 고함량으로 함유하면서 당류계 계면활성제 및 소르비탄계 계면활성제를 함유하는 실시예 1 내지 7은 칼라민이 유상인 내상에 잘 안정화되어, 고온 안정도와 가속 안정도 모두 우수한 결과를 나타내었다. 실시예 2, 3의 경우에는 실시예 1을 기준으로 칼라민의 함량을 2배, 3배 증량함에 따라 칼라민 분산에 효과적인 소르비탄계 계면활성제를 증량하여 처방하였으며, 그 결과 칼라민의 함량이 10 내지 15 중량%에 이르는 경우에도 모두 안정도가 우수한 제형을 얻을 수 있음을 확인하였다. 이때의 당류계 계면활성제 및 상기 소르비탄계 계면활성제의 혼합비율은 중량 기준으로 2.5 : 0.6 내지 2.5인 것이 바람직하였다.또한 칼라민의 함량을 5 중량%로 고정하고 계면활성제의 종류를 바꿔 테스트한 결과, 당류계 계면활성제 1종 이상과 소르비탄계 계면활성제 1종 이상을 동시에 함유한 실시예 1 및 실시예 4 내지 7은 고온 안정도와 가속 안정도 모두 우수한 결과를 나타내었다. As can be seen from the above Table 3, Examples 1 to 7, which contain a high content of calamine in an amount of 5 to 15% by weight and contain a saccharide-based surfactant and a sorbitan-based surfactant, And both of high temperature stability and acceleration stability showed excellent results. In the case of Examples 2 and 3, the content of the calamine was increased by 2 times and 3 times, respectively, based on Example 1, and the sorbitan surfactant effective for the dispersion of the calamine was increased and prespecified. As a result, It was confirmed that a formulation having excellent stability was obtained even when it reached 15% by weight. The mixing ratio of the saccharide surfactant and the sorbitan surfactant at this time was preferably 2.5: 0.6 to 2.5 on a weight basis. Further, the content of the coloramine was fixed to 5% by weight and the kind of the surfactant was changed , Example 1 and Examples 4 to 7 each containing at least one saccharide surfactant and at least one sorbitan surfactant exhibited excellent results in both high temperature stability and acceleration stability.
그 중에서도 실시예 1은, 도 1의 결과를 통해, 제조 후 2주 동안 45℃에서 보관한 뒤에도 수상과 유상의 분리가 전혀 나타나지 않고, 비교예 1 내지 5에 비해 매우 안정함을 육안으로도 확인할 수 있었다. 그리고 도 2에서 확인할 수 있듯이, 실시예 1의 조성으로 수중유형에 안정화한 크림을 피부에 펴 발랐을 때, 파우더 입자가 전혀 뭉침 없이 고르게 분산되어 있는 것을 확인할 수 있었다.Among them, in Example 1, the result of Fig. 1 shows that even after storage at 45 캜 for 2 weeks after the preparation, no separation of the water phase and oil phase occurs, and it is visually confirmed that it is very stable as compared with Comparative Examples 1 to 5 I could. As can be seen from FIG. 2, when the cream stabilized in the water-in-oil type was applied onto the skin in the composition of Example 1, it was confirmed that the powder particles were uniformly dispersed without any lumps.
한편, 실시예 중에서도 당류계 계면활성제를 2종 혼합하여 사용한 실시예 4와 실시예 5를 비교했을 때, 세테아릴알코올*세테아릴글루코시드의 함량이 실시예 4보다 높은 실시예 5의 경우에, 관찰 결과 제형의 경도가 가장 높게 형성되어 장기 안정도가 더 우수할 가능성이 높을 것으로 예상되었다. 이것은 세테아릴알코올*세테아릴글루코시드에 포함된 지방알코올이 세테아릴글루코시드가 형성한 O/W 계면막 주위에 액정을 형성하면서 계면막을 더 단단하게 유지시켜줌으로써 경도를 높인 결과로 보인다.On the other hand, when Example 4 and Example 5 in which two kinds of sugar-based surfactants were used were compared among Examples, when the content of cetearyl alcohol * cetearyl glucoside was higher than that of Example 4 , It was expected that the hardness of the formulation was found to be the highest, resulting in a higher possibility that the long-term stability was more excellent. This results from the fact that the fatty alcohol contained in the cetearyl alcohol * cetearyl glucoside increases the hardness by forming a liquid crystal around the O / W interface film formed by cetearyl glucoside while keeping the interface film harder .
그러나, 상기 표 4에서 확인할 수 있는 바와 같이, 당류계 계면활성제만 단독으로 사용한 비교예 4는 가속 안정도는 양호했지만 고온 안정도가 보통인 결과를 나타내어 가속 안정도에 비해 고온 안정도가 더 취약하다는 것을 알 수 있었다. 다른 비교예의 경우는 고온 안정도와 가속 안정도가 비슷한 양상을 보였으나, 비교예 4는 고온에 노출되었을 때 더 큰 영향을 받는 경향이 있었다. 또한 비교예 4는 도 1에서 볼 수 있듯이 고온에서 제형이 점차 뭉글거리며 칼라민이 뭉치면서 가장자리에 물이 고이는 현상이 발생해 전반적으로 안정도가 매우 불안정함을 다시 확인하였다.However, as can be seen from the above Table 4, Comparative Example 4 using only a saccharide surfactant showed good stability in acceleration, but showed normal stability at a high temperature, indicating that the stability at high temperature was weaker than the acceleration stability there was. In the case of the other comparative examples, the high temperature stability and the acceleration stability were similar, but the comparative example 4 tended to be more influenced when exposed to high temperature. In Comparative Example 4, as shown in FIG. 1, it was confirmed that the stability was very unstable due to the phenomenon that the formulation gradually spreads at a high temperature and the water accumulates on the edge of the aggregate.
그리고 소르비탄계 계면활성제만 단독으로 사용한 비교예 5는 상기 표 4에서 확인할 수 있듯이 제형이 분리되어 안정화되지 못하였다. 이를 통해 당류계 계면활성제를 제외하고 소르비탄계 계면활성제만을 사용하여 제형을 만들 경우, 그 안정도가 현저히 좋아지지 않는다는 것을 알 수 있었다. 이는 소르비탄계 계면활성제가 칼라민 파우더의 분산 안전성을 도모하는 데는 큰 역할을 하고 있으나, 안정한 O/W 유화 입자를 형성하는 데에 있어 당류계 계면활성제와 함께 사용했을 때에야 비로소 그 역할을 할 수 있다는 것을 알 수 있다.In Comparative Example 5 in which only the sorbitan surfactant was used alone, the formulation could not be separated and stabilized as shown in Table 4 above. As a result, it was found that the stability was not improved remarkably when a formulation was prepared using only a sorbitan surfactant except a saccharide surfactant. This is because the sorbitan surfactant plays a major role in stabilizing the dispersion stability of the calamine powder, but it can only play a role in forming stabilized O / W emulsified particles when used with a sugar surfactant .
한편, 소르비탄계 계면활성제 대신 음이온성 계면활성제를 사용한 비교예 1 및 비교예 2는 상기 표 4 및 도 1에서 확인할 수 있듯이 바로 분리되어 제형이 안정적으로 형성되지 않았다. 45℃에 2주 가까이 노출 시, 물이 분리되면서 파우더가 엉기는 현상이 발견되었다. 그리고 소르비탄계 계면활성제 대신 PEG계 계면활성제인 피이지-100 스테아레이트를 사용한 비교예 3도 상기 표 4 및 도 1에서 확인할 수 있듯이 제형은 형성되나 고온 안정도와 가속 안정도가 좋지 않아 장기 안정도가 저하되는 것으로 나타났다.On the other hand, Comparative Example 1 and Comparative Example 2 using the anionic surfactant instead of the sorbitan surfactant did not form a stable formulation as shown in Table 4 and FIG. When exposed to 45 ° C for two weeks, the powder disintegrated as the water separated. In Comparative Example 3 using PEG-100 stearate as a PEG surfactant instead of a sorbitan surfactant, the formulation was formed as shown in Table 4 and FIG. 1, but the stability at a high temperature and the stability in acceleration were poor, .
상기 실시예 및 비교예와 시험예를 통해 당류계 계면활성제 및 소르비탄계 계면활성제를 함께 사용하여 칼라민을 내상에 안정화시키면 고함량의 칼라민을 함유하는 수중유형 화장료 조성물을 얻을 수 있음을 확인하였다. 특히 당류계 계면활성제 및 소르비탄계 계면활성제를 중량 기준으로 2.5 : 0.6 내지 2.5 비율로 사용할 때 고함량의 칼라민을 수중유형의 내상에 성공적으로 안정화시켜 장기 안정성을 확보할 수 있었다. 이로써 고함량의 칼라민이 내상에 안정화된 본 발명의 수중유형 화장료 조성물은 발림성 등의 사용감을 개선하고 피부 흡수력을 향상시킬 수 있게 되었다.It has been confirmed through the above examples, comparative examples and test examples that when a saccharide surfactant and a sorbitan surfactant are used together to stabilize the calamine in the inner phase, an underwater type cosmetic composition containing a high content of calamine can be obtained Respectively. In particular, when a saccharide surfactant and a sorbitan surfactant are used at a ratio of 2.5: 0.6 to 2.5 on a weight basis, a high content of calamine can be successfully stabilized in the water-in-oil type to ensure long-term stability. As a result, the water-in-oil type cosmetic composition of the present invention, in which a high content of calamine is stabilized in the inner phase, can improve the feeling of use such as wetting and improve the absorbency of the skin.

Claims (11)

  1. 당류계 계면활성제 및 소르비탄계 계면활성제(Sorbitan Ester)를 안정화제로 함유하여, 칼라민(Calamine)을 내상에 안정화한 수중유형 화장료 조성물.A water-in-oil cosmetic composition comprising a saccharide surfactant and a sorbitan ester as a stabilizer and stabilizing calamine.
  2. 제 1항에 있어서, 상기 소르비탄계 계면활성제는 소르비탄 에스테르(Sorbitan Ester) 또는 소르비탄 에스테르와 산화 에틸렌의 부가중합체인 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater type cosmetic composition according to claim 1, wherein the sorbitan surfactant is an addition polymer of sorbitan ester or sorbitan ester and ethylene oxide.
  3. 제 2항에 있어서, 상기 소르비탄계 계면활성제는 소르비탄올리베이트(Sorbitan Olivate), 소르비탄스테아레이트(Sorbitan Stearate), 소르비탄이소스테아레이트(Sorbitan Isostearate), 소르비탄트리스테아레이트(Sorbitan Tristearate), 소르비탄세스퀴스테아레이트(Sorbitan Sesquistearate), 소르비탄팔미테이트(Sorbitan Palmitate), 소르비탄라우레이트(Sorbitan Laurate), 소르비탄올리에이트(Sorbitan Oleate), 소르비탄세스퀴올리에이트(Sorbitan Sesquioleate), 소르비탄트리올리에이트(Sorbitan Trioleate), 소르비탄스테아레이트/소르비틸라우레이트(Sorbitan Stearate and Sorbityl Laurate), 폴리소르베이트 20(Polysorbate 20), 폴리소르베이트 40, 폴리소르베이트 60, 폴리소르베이트 65, 폴리소르베이트 80, 및 폴리소르베이트 85로 이루어진 군에서 선택되는 1종 이상인 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The composition of claim 2, wherein the sorbitan surfactant is selected from the group consisting of sorbitan olivate, sorbitan stearate, sorbitan isostearate, sorbitan tristearate, ), Sorbitan sesquistearate, sorbitan palmitate, sorbitan laurate, sorbitan oleate, sorbitan sesquioleate, sorbitan sesquioleate, , Sorbitan trioleate, sorbitan stearate and sorbitol laurate, polysorbate 20, polysorbate 40, polysorbate 60, polysorbate 60, 65, polysorbate 80, and polysorbate 85, wherein the calamine is stabilized in the inner phase An underwater type cosmetic composition.
  4. 제 1항에 있어서, 상기 당류계 계면활성제는 알킬폴리글리코시드(Alkyl polyglycoside, APGs)류 계면활성제 및 당에스테르(Sugar ester)류 계면활성제 중에서 선택되는 1종 이상인 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The method according to claim 1, wherein the saccharide surfactant is at least one selected from the group consisting of alkyl polyglycoside (APGs) surfactants and sugar ester surfactants. Wherein the composition is stabilized in water.
  5. 제 4항에 있어서, 상기 알킬폴리글리코시드류 계면활성제는 C14-22알코올*C12-20알킬글루코시드(C14-22 Alcohols and C12-20 Alkyl Glucoside), 세테아릴알코올*세테아릴글루코시드(Cetearyl Alcohol and Cetearyl Glucoside), 베헤닐알코올*아라키딜글루코시드*아라키딜알코올(Behenyl Alcohol and Arachidyl Alcohol and Arachidyl Glucoside), 세테아릴알코올*코코글루코시드(Cetearyl alcohol and Coco-Glucoside)로 이루어진 군에서 선택되는 1종 이상인 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The method of claim 4, wherein the alkyl polyglycoside surfactant is selected from the group consisting of C14-22 alcohol * C12-20 alkyl glucoside (C14-22 Alcohols and C12-20 Alkyl Glucoside), cetearyl alcohol * cetearyl glucoside Cetearyl Alcohol and Cetearyl Glucoside, Behenyl Alcohol and Arachidyl Alcohol and Arachidyl Glucoside, Cetearyl Alcohol and Coco-Glucoside, Wherein at least one kind selected from the group consisting of water-in-oil and water-in-oil type is stabilized in the inner phase.
  6. 제 4항에 있어서, 상기 당에스테르류 계면활성제는 폴리글리세릴-3메칠글루코스디스테아레이트(Polyglyceryl-3 Methylglucose Distearate)인 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater-type cosmetic composition according to claim 4, wherein the sugar ester surfactant is polyglyceryl-3 methylglucose distearate.
  7. 제 1항에 있어서, 상기 칼라민의 함량은 조성물 총 중량에 대하여 0.01 내지 15 중량%임을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater type cosmetic composition according to claim 1, wherein the content of the calamine is 0.01 to 15% by weight based on the total weight of the composition.
  8. 제 1항에 있어서, 상기 당류계 계면활성제의 함량은 조성물 총 중량에 대하여 0.1 내지 8 중량%임을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater-type cosmetic composition according to claim 1, wherein the content of the saccharide-based surfactant is 0.1 to 8% by weight based on the total weight of the composition.
  9. 제 1항에 있어서, 상기 소르비탄계 계면활성제의 함량은 조성물 총 중량에 대하여 0.01 내지 5 중량%임을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater-type cosmetic composition according to claim 1, wherein the content of the sorbitan surfactant is 0.01 to 5% by weight based on the total weight of the composition.
  10. 제 1항에 있어서, 상기 당류계 계면활성제 및 상기 소르비탄계 계면활성제는 중량 기준으로 2.5 : 0.6 내지 2.5의 비율로 함유되는 것을 특징으로 하는, 칼라민을 내상에 안정화한 수중유형 화장료 조성물.The underwater-type cosmetic composition according to claim 1, wherein the saccharide-based surfactant and the sorbitan-based surfactant are contained in a ratio of 2.5: 0.6 to 2.5 based on weight.
  11. 제 1항 내지 제 9항 중 어느 한 항에 따른 칼라민을 내상에 안정화한 수중유형 화장료 조성물을 제형화하여 제조한 화장품.9. A cosmetic product produced by formulating an underwater-type cosmetic composition stabilized in the form of a colamine according to any one of claims 1 to 9.
PCT/KR2018/014352 2017-11-22 2018-11-21 Oil-in-water cosmetic composition containing high-content calamine stabilized in inner phase WO2019103453A2 (en)

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