WO2016147503A1 - Mems圧力センサとその位置決め方法 - Google Patents
Mems圧力センサとその位置決め方法 Download PDFInfo
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- WO2016147503A1 WO2016147503A1 PCT/JP2015/084799 JP2015084799W WO2016147503A1 WO 2016147503 A1 WO2016147503 A1 WO 2016147503A1 JP 2015084799 W JP2015084799 W JP 2015084799W WO 2016147503 A1 WO2016147503 A1 WO 2016147503A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02444—Details of sensor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
- A61B5/6833—Adhesive patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/684—Indicating the position of the sensor on the body
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
- G01L19/00—Details of, or accessories for, apparatus for measuring steady or quasi-steady pressure of a fluent medium insofar as such details or accessories are not special to particular types of pressure gauges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0247—Pressure sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/028—Microscale sensors, e.g. electromechanical sensors [MEMS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6824—Arm or wrist
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/684—Indicating the position of the sensor on the body
- A61B5/6842—Indicating the position of the sensor on the body by marking the skin
Definitions
- the present invention relates to a micro electro mechanical systems (hereinafter referred to as MEMS) pressure sensor device, a pressure measurement system using the pressure sensor device, and a MEMS pressure sensor positioning method.
- MEMS micro electro mechanical systems
- Patent Document 1 discloses a measurement system that measures, for example, the pulse pressure of the radial artery using an optical sensor.
- an optical probe including a light emitting element that emits light to a blood vessel through the skin and a light receiving element that receives reflected light from the blood vessel or transmitted light through the blood vessel through the skin.
- An optical probe circuit including a touch element, a drive circuit that drives a light emitting element based on an input drive signal, and a detection circuit that converts light received by the light receiving element into an electrical signal and outputs the signal is used.
- the self-excited oscillation signal is generated from the detection circuit by directly synchronizing and feeding back the electrical signal as a drive signal to the drive circuit. It is characterized by comprising measurement means for measuring as a pulse wave signal, and control means for controlling the operating point of at least one of the detection circuit and the drive circuit so that the level of the self-excited oscillation signal is substantially maximized. .
- FIG. 1 is a schematic view showing a configuration example of a pulse wave sphygmomanometer system according to a conventional example
- FIG. 1 (a) is a longitudinal sectional view seen from the side of a MEMS pressure sensor 220
- FIG. 1 (b) is a wrist
- FIG. 2 is a longitudinal sectional view showing a measurement state when the MEMS pressure sensor 220 of FIG. 1 is brought into close contact with the radial artery portion 7 of the wrist 8 (for example, Patent Literature 1). 2).
- a MEMS pressure sensor 220 is connected to a pulse wave sphygmomanometer main body 210 via connectors 211a and 211b by cables and measures blood pressure by a known method based on a vascular pulse wave signal.
- the voltage signal obtained by pressure / voltage conversion of the pressure fluctuation of the radial artery pressure detected by the MEMS pressure sensor 220 is obtained.
- the blood pressure of the measurement subject can be measured by converting the blood pressure into a blood pressure using a method in which the voltage signal is associated with the standard blood pressure value measured in advance.
- the diameter of the pressure detecting cavity hole 220h of the MEMS pressure sensor 220 is as small as about 1 mm, there are the following problems. (1) The amplitude of the signal waveform from the MEMS pressure sensor 220 is small, contains a lot of noise, the signal quality is extremely poor, and the signal-to-noise power ratio (S / N ratio) is extremely small. (2) Since the site of the radial artery portion 7 is very narrow, the position range where the detection portion of the MEMS pressure sensor 220 is placed is extremely narrow.
- the object of the present invention is to solve the above-described problems, and the detection part of the MEMS pressure sensor can be accurately positioned, for example, at the site of the radial artery part 7 as compared with the conventional example. It is to provide a MEMS pressure sensor capable of obtaining a / N ratio, a pressure measurement system using the same, and a positioning method of the MEMS pressure sensor.
- the MEMS pressure sensor according to the first invention is The diaphragm has a first space on the pressure detection surface side, and has a diaphragm for detecting pressure using the pressure detection surface facing the first space, and outputs an electrical signal corresponding to the detected pressure.
- a MEMS pressure sensor The first film sheet that supports the MEMS pressure sensor and is placed in contact with the part to be measured, the pressure detection surface communicating with the first space and larger than the first space.
- the apparatus Before placing on the measuring section, the apparatus further comprises a second film sheet for placing the portion to be measured so that the portion of the portion to be measured is positioned in the third space.
- the first space, the second space, and the third space are hermetically sealed when the MEMS pressure sensor device is placed on the measured part via the second film sheet.
- the pressure of the measured part is transmitted to the diaphragm of the MEMS pressure sensor through the first space, the second space, and the third space, and the MEMS pressure sensor detects the pressure. It is characterized by performing.
- the first space, the second space, and the third space each have a bottom surface substantially parallel to the pressure detection surface of the diaphragm and are substantially coaxial with each other. It is characterized by having a cylindrical shape or an elliptical cylindrical shape.
- the diameter of the bottom surface of the third space is larger than the diameter of the bottom surface of the second space.
- the diameter of the bottom surface of the second space is larger than the diameter of the bottom surface of the first space.
- the first and second film sheets are adhesive sheets.
- the pressure measurement system is: The MEMS pressure sensor device; And a pressure measuring unit that calculates and outputs a pressure value by referring to a relationship between an electric signal level measured in advance and a pressure value based on an electric signal from the MEMS pressure sensor device.
- the third space of the MEMS pressure sensor device is provided in close proximity to the blood vessel of the measurement target portion so as to detect pressure,
- the pressure measuring unit calculates and outputs a pulse pressure value that is the pressure value.
- a positioning method of the MEMS pressure sensor device is as follows.
- the diaphragm has a first space on the pressure detection surface side, and has a diaphragm for detecting pressure using the pressure detection surface facing the first space, and outputs an electrical signal corresponding to the detected pressure.
- a method for positioning a MEMS pressure sensor device comprising: a first film sheet having a second space having a size in a direction parallel to Using the second film sheet having a third space having a size in a direction parallel to the pressure detection surface, the second film is so positioned that the part to be measured is located in the third space. Placing the sheet on the portion of the measured part; Next, the MEMS pressure sensor device having the first film sheet is placed on the second film sheet so that the second space is positioned in the third space, thereby the MEMS pressure sensor device. Positioning to the part to be measured.
- the detection part of the MEMS pressure sensor is accurately positioned at the site of the radial artery part 7 as compared with the conventional example. Therefore, a larger S / N ratio can be obtained as compared with the conventional example.
- FIG. 3 is a longitudinal sectional view showing a measurement state when the MEMS pressure sensor 220 of FIG. 1 is brought into close contact with the radial artery portion 7 of the wrist 8.
- FIG. It is a longitudinal cross-sectional view which shows the structure of the pressure sensor part 40 which concerns on Embodiment 1 of this invention. It is a bottom view of the pressure sensor part 40 of FIG. 3A.
- FIG. 3A It is a block diagram which shows the structure of the pulse pressure measurement system 100 using the pressure sensor part 40 of FIG. 3A. It is a perspective view which shows the pressure sensor part 40 which attached the pressure sensor part 40 of FIG. 3A to the radial artery part 7 of the to-be-measured person 6.
- FIG. It is a longitudinal cross-sectional view which shows the structure of 40 A of pressure sensor parts which concern on Embodiment 2 of this invention. It is a longitudinal cross-sectional view which shows pressure sensor part 40A which attached 40 A of pressure sensor parts of FIG. 6 to the radial artery part 7 of the to-be-measured person 6.
- FIG. 1 is a photograph of a signal waveform of an experimental result when measuring a pulse wave signal of a radial artery using the MEMS pressure sensor 220 of FIG. 1 according to a conventional example, and (a) is an output signal waveform of the MEMS pressure sensor 220.
- FIG. Yes (b) is a signal waveform when the output signal is passed through a low-pass filter.
- 6 is a photograph of a signal waveform of an experimental result when measuring a pulse wave signal of a radial artery using the MEMS pressure sensor 40A of FIG. 6 according to the second embodiment, and (a) is an output of the MEMS pressure sensor 40A.
- (B) is a signal waveform when the output signal is passed through a low-pass filter.
- FIG. 3A is a longitudinal sectional view showing the configuration of the pressure sensor unit 40 according to Embodiment 1 of the present invention
- FIG. 3B is a bottom view of the pressure sensor unit 40 of FIG. 3A.
- the MEMS pressure sensor 1 is fixed using a plurality of solder balls 31.
- a space 30 corresponding to the thickness of the solder ball 31 is formed.
- the MEMS pressure sensor 1 has, for example, a rectangular flat plate shape having a width d3, and has a diaphragm 2 that is a pressure detection surface 2a having, for example, a circular or elliptical shape at the center thereof.
- the space 30 is formed on the surface 2b side of the diaphragm 2 facing the pressure detection surface 2a.
- the diaphragm 2 has a thickness t3 that is thinner than the thickness t2 of the MEMS pressure sensor 1 in the vicinity of the uppermost portion of the MEMS pressure sensor 1, and is a space that is, for example, a cylindrical or elliptical cylindrical hole below the diaphragm 2. 21 is formed.
- the space 21 is sealed with respect to the diaphragm 2, but the lower direction is open, and the space 21 and the space 30 are not communicated with each other.
- the MEMS pressure sensor 1 has a space 21 having a height t2 on the pressure detection surface 2a side of the diaphragm 2, and detects pressure using the pressure detection surface 2a facing the space 21, and the electric pressure corresponding to the detected pressure is detected.
- the signal is output through a cable 41 inserted through the dielectric substrate 10.
- a pad 11 having a thickness t3 which is, for example, a double-sided adhesive sheet is attached to a part of the lower surface 10a of the dielectric substrate 10 and a part of the side surface 1a and the lower surface 1b of the MEMS pressure sensor 1.
- the pressure sensor 1 and the dielectric substrate 10 are supported.
- the pad 11 is supported by a bottom surface 11b (having a hole of a downward space 22 described later in the center) of the space in the center of the thickness (t3-t4) of the upper part.
- the pad 11 is placed so that the bottom surface 11a of the pad 11 is in contact with the measured portion, for example, the radial artery portion 7 (see FIG.
- the space 22 is a through-hole having a size in a direction parallel to the pressure detection surface 2a, which is larger than the space 21.
- each of the space 21 and the space 22 has a bottom surface substantially parallel to the pressure detection surface 2a of the diaphragm 2, and has a substantially cylindrical shape or an elliptical cylinder shape that is coaxial with each other, or a square shape, for example. It has a shape such as a square shape or a rectangular shape.
- the diameter d2 of the bottom surface of the space 22 is configured to be larger than the diameter d1 of the bottom surface of the space 21.
- the pressure sensor unit 40 configured as described above When the pressure sensor unit 40 configured as described above is placed in contact with the measurement target portion, for example, the radial artery portion 7 (see FIG. 5) of the wrist 8 of the measurement subject, the space 21 and the space 22 are placed. Is sealed to form a sealed space, and the pressure of the part to be measured is transmitted to the diaphragm 2 of the MEMS pressure sensor 1 through the space 21 and the space 22, and the MEMS pressure sensor 1 detects the pressure. A pressure detection signal of the MEMS pressure sensor 1 is output via the cable 41.
- FIG. 4 is a block diagram showing a configuration of the pulse pressure measurement system 100 using the pressure sensor unit 40 of FIG. 3A.
- the pressure detection signal from the pressure sensor unit 40 placed so that the space 22 of the pressure sensor unit 40 is close to the measurement subject 6, for example, the radial artery unit 7 so as to detect pressure is a cable 41, a connector
- the signal is input to the signal amplifier 43 of the signal relay unit 120 via 42a and 42b.
- the signal amplifier 43 amplifies the input pressure detection signal and inputs the amplified pressure detection signal to the A / D converter 53 of the pulse pressure measuring unit main body 110 via the cable 44.
- the pulse pressure measuring unit main body 110 includes, for example, a device controller 50 including a blood vessel pulse pressure measurement processing module 51 and an internal memory 50m, a display unit 52 such as a liquid crystal display, and an A / D converter 53. It is prepared for.
- the A / D converter 53 A / D converts the input pressure detection signal into digital data, and then outputs it to the device controller 50.
- the apparatus controller 50 executes the processing of the blood vessel pulse pressure measurement processing module 51, thereby preliminarily measuring and storing the signal level versus pressure value calibration table (the electric signal level and pressure value of the pressure detection signal) in the internal memory 50m.
- the digital data of the pressure detection signal is converted into a pulse pressure value and output to the display unit 52 for display.
- the apparatus controller 50 calculates the vascular pulse wave signal by executing the above vascular pulse pressure measurement process in real time and displays it on the display unit 52.
- FIG. 5 is a perspective view showing the pressure sensor unit 40 in which the pressure sensor unit 40 of FIG. 3A is attached to the radial artery portion 7 of the person 6 to be measured. As apparent from FIG. 5, the pressure sensor 40 is attached to the radial artery 7 of the person to be measured 6 to measure the pulse pressure.
- the inventors made a prototype of the pressure sensor unit 40 and the pulse pressure measurement system 100 according to the embodiment of the present invention.
- the design result that the diameter d1 of the diaphragm 2 (space 21) of the MEMS pressure sensor 1 of the pressure sensor unit 40 is most preferably about 1 mm was obtained.
- the length d4 of one side of the dielectric substrate 10 and the pad 11 is 3 to 4 mm
- the diameter d2 of the space 22 is 2 to 3 mm.
- the thickness t2 of the MEMS pressure sensor 1 was 400 ⁇ m
- the thickness of the lower portion of the pad 11 was 0.5 to 1 mm.
- the pressure sensor unit 40 When the pressure sensor unit 40 according to the present embodiment configured as described above is placed on the measurement target, the space 21 and the space 22 are sealed to form a sealed space, and the pressure of the measurement target is changed to the space 21 and the space.
- the pressure is transmitted to the diaphragm 2 of the MEMS pressure sensor 1 through 22 and the MEMS pressure sensor 1 detects the pressure. Therefore, even if the position of the MEMS pressure sensor 1 is deviated from the measurement position, the pressure of the part to be measured can be accurately measured.
- non-invasive blood pressure pulse waves can be measured over a long period of time.
- FIG. FIG. 6 is a longitudinal sectional view showing a configuration of a pressure sensor unit 40A according to Embodiment 2 of the present invention.
- the pressure sensor unit 40 ⁇ / b> A according to the second embodiment is different from the pressure sensor unit 40 of FIG. 3A in the following points.
- (1) The bottom surface portion of the pad 11 was deleted, and the film sheet 12 having a thickness t4 was adhered.
- the film sheet 12 forms a space 22 in the center thereof by the pressure detecting cavity 12h.
- a film sheet 13 that adheres to the radial artery portion 7 of the wrist 8 in advance is further provided.
- the film sheet 13 forms a space 23 having a size in a direction parallel to the pressure detection surface by a pressure detection cavity 13h at the center thereof.
- the diameter d5 of the pressure detection cavity 13h is larger than the diameter d2 of the pressure detection cavity 12h of the film sheet 12.
- the sealed spaces described in the first embodiment are configured by the spaces 21, 22, and 23.
- a mark 10C indicating the center is preferably drawn at the center of the upper surface of the dielectric substrate 10 of the pressure sensor 40A.
- the pressure sensor part 40A is provided on the radial artery part 7 of the wrist 8 of the person to be measured in order to detect vascular pulsation with a higher S / N ratio. It is necessary to place it accurately.
- the following procedure is used as shown in FIG. (Step A) First, the film sheet 13 is affixed to the position of the radial artery portion 7 (preferably the place where the position where the pulse can be taken first is confirmed and marked) is preferred.
- the film sheet 13 is positioned so that the adhesive lower surface 13b of the film sheet 13 adheres to the skin surface of the radial artery part 7 and the central part of the pressure detection cavity 13h of the film sheet 13 is located in the radial artery part 7. And paste it.
- the film sheet 12 of the pressure sensor unit 40 ⁇ / b> A is attached to the upper surface 13 a of the film sheet 13.
- the mark 10C is positioned at the center of the pressure detection cavity hole 13h, that is, the center of the pressure detection cavity hole 12h of the film sheet 12 is positioned at the center of the pressure detection cavity hole 13h.
- the pressure sensor portion 40A having the film sheet 12 is positioned.
- FIG. 7 is a longitudinal sectional view showing the pressure sensor unit 40A in which the pressure sensor unit 40A of FIG. 6 is attached to the radial artery portion 7 of the person to be measured 6. That is, FIG. 7 shows a state after step B.
- the sealed spaces 21, 22, and 23 for detecting pulsation by the MEMS sensor can be reliably formed in the two-step pasting step.
- the pressure sensor unit 40A of the second embodiment is similar to the pressure sensor unit 40 according to the first embodiment, and when the pressure sensor unit 40A is placed on the measurement target, the spaces 21, 22, and 23 are sealed. A space is formed, and the pressure of the part to be measured is transmitted to the diaphragm 2 of the MEMS pressure sensor 1 through the spaces 21, 22 and 23, and the MEMS pressure sensor 1 detects the pressure. Therefore, even if the position of the MEMS pressure sensor 1 is deviated from the measurement position, the pressure of the part to be measured can be accurately measured. In addition, since it is not necessary to apply pressure to the part to be measured, for example, non-invasive blood pressure pulse waves can be measured over a long period of time.
- FIG. 8 is a photograph of a signal waveform of an experimental result when measuring the pulse wave signal of the radial artery using the MEMS pressure sensor 220 of FIG. 1 according to the conventional example, and FIG. FIG. 8B is a signal waveform when the output signal is passed through the low-pass filter.
- 9 is a photograph of a signal waveform of an experimental result when the pulse wave signal of the radial artery is measured using the MEMS pressure sensor unit 40A of FIG. 6 according to the second embodiment, and FIG. It is an output signal waveform of the MEMS pressure sensor unit 40A, and FIG. 9B is a signal waveform when the output signal is passed through the low-pass filter.
- the signal waveform of the second embodiment has a significantly higher S / N ratio in both the output waveform of the sensor and the signal waveform after low-pass compared to the signal waveform of the conventional example. Can be measured.
- the pulse pressure measurement system and the blood pressure measurement system have been described.
- the pressure measurement system measures the pulse pressure of animals other than humans and general pressure. And can be applied to a blood pressure measurement system.
- the pressure sensor units 40 and 40A can be used as a pressure sensor device, and can detect not only the pulse pressure of blood vessels but also the pulse pressures of animals other than humans and general pressures.
- each cavity hole is not limited to a cylindrical shape, and may be an elliptical cylindrical shape.
- the MEMS pressure sensor device when the MEMS pressure sensor device is placed on the measurement target portion, a sealed space is formed, and the pressure of the measurement target portion passes through two or three spaces.
- the MEMS pressure sensor is transmitted to the diaphragm and detects the pressure. Therefore, even if the position of the MEMS pressure sensor is deviated from the measurement position, the pressure of the part to be measured can be accurately measured.
- non-invasive blood pressure pulse waves can be measured over a long period of time.
- the detection part of the MEMS pressure sensor can be accurately positioned at the radial artery part as compared with the conventional example, and a large S / N ratio can be obtained as compared with the conventional example. it can.
- a / D converter 100: Pulse pressure measurement system, 110 ... pulse pressure measuring unit main body, 120 ... signal relay part, 210 ... pulse wave sphygmomanometer body, 211a, 211b ... connectors, 220 ... MEMS pressure sensor, 220h: Pressure detection cavity hole.
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Abstract
Description
(1)MEMS圧力センサ220からの信号波形の振幅が小さく、雑音を多く含み、信号品質がきわめて悪く、信号対雑音電力比(S/N比)がきわめて小さい。
(2)橈骨動脈部7の部位が非常に狭いために、MEMS圧力センサ220の検知部を載置する位置範囲がきわめて狭い。
ダイアフラムの圧力検出面側に第1の空間を有し、上記第1の空間に対面する圧力検出面を用いて圧力の検出を行うダイアフラムを有し、検出した圧力に対応する電気信号を出力するMEMS圧力センサと、
上記MEMS圧力センサを支持して被測定部に接触して載置される第1のフィルムシートであって、上記第1の空間に連通しかつ上記第1の空間よりも大きな、上記圧力検出面に平行な方向のサイズを有する第2の空間を有する第1のフィルムシートとを備えるMEMS圧力センサ装置であって、
上記MEMS圧力センサ装置を上記被測定部に位置決めするために上記圧力検出面に平行な方向のサイズを有する第3の空間を有する第2のフィルムシートであって、上記MEMS圧力センサ装置を上記被測定部に載置する前に、上記被測定部の部位が上記第3の空間に位置するように載置するための第2のフィルムシートをさらに備えたことを特徴とする。
上記MEMS圧力センサ装置と、
上記MEMS圧力センサ装置からの電気信号に基づいて、予め計測された電気信号レベルと圧力値との関係を参照して圧力値を算出して出力する圧力計測部とを備えることを特徴とする。
上記圧力計測部は上記圧力値である脈圧値を算出して出力することを特徴とする。
ダイアフラムの圧力検出面側に第1の空間を有し、上記第1の空間に対面する圧力検出面を用いて圧力の検出を行うダイアフラムを有し、検出した圧力に対応する電気信号を出力するMEMS圧力センサと、
上記MEMS圧力センサを支持して被測定部に接触して載置される第1のフィルムシートであって、上記第1の空間に連通しかつ上記第1の空間よりも大きな、上記圧力検出面に平行な方向のサイズを有する第2の空間を有する第1のフィルムシートとを備えるMEMS圧力センサ装置の位置決め方法であって、
上記圧力検出面に平行な方向のサイズを有する第3の空間を有する第2のフィルムシートを用いて、上記被測定部の部位が上記第3の空間に位置するように、上記第2のフィルムシートを上記被測定部の部位上に載置するステップと、
次いで、上記第1のフィルムシートを有するMEMS圧力センサを、上記第2の空間が上記第3の空間に位置するように上記第2のフィルムシート上に載置することで、上記MEMS圧力センサ装置を上記被測定部に位置決めするステップとを含むことを特徴とする。
図3Aは本発明の実施形態1に係る圧力センサ部40の構成を示す縦断面図であり、図3Bは図3Aの圧力センサ部40の底面図である。
図6は本発明の実施形態2に係る圧力センサ部40Aの構成を示す縦断面図である。図6において、実施形態2に係る圧力センサ部40Aは、図3Aの圧力センサ部40に比較して以下の点が異なる。
(1)パッド11の底面部を削除して厚さt4のフィルムシート12を接着させた。ここで、フィルムシート12はその中央部に圧力検知用空洞孔12hにより空間22を形成する。
(2)フィルムシート12を有する圧力センサ部40Aの位置決めのために、事前に手首8の橈骨動脈部7に接着するフィルムシート13をさらに備える。フィルムシート13はその中央部に圧力検知用空洞孔13hにより、圧力検出面に平行な方向のサイズを有する空間23を形成する。ここで、フィルムシート13の橈骨動脈部7への貼付を容易にするために、圧力検知用空洞孔13hの直径d5は、フィルムシート12の圧力検知用空洞孔12hの直径d2よりも大きい。構成例では、d5=5mm、d2=3mmである。また、空間21,22,23により実施形態1において説明した密閉空間を構成する。
(3)圧力センサ部40Aの誘電体基板10の上面の中央部に中央を示すマーク10Cを好ましくは描いておく。
(ステップA)最初に橈骨動脈部7の位置(最初に脈の取れる位置を確認しマーキングした箇所が好ましい)にフィルムシート13を貼付する。ここで、フィルムシート13の接着下面13bが橈骨動脈部7の皮膚表面に接着し、フィルムシート13の圧力検知用空洞孔13hの中央部が橈骨動脈部7に位置するようにフィルムシート13を位置決めして貼付する。
(ステップB)次いで、フィルムシート13の上面13aに、圧力センサ部40Aのフィルムシート12を貼付する。ここで、マーク10Cが圧力検知用空洞孔13hの中央部に位置するように、すなわち、フィルムシート12の圧力検知用空洞孔12hの中央部が圧力検知用空洞孔13hの中央部に位置するように、フィルムシート12を有する圧力センサ部40Aを位置決めする。
2…ダイアフラム、
6…被測定者、
7…橈骨動脈部、
8…手首、
10…誘電体基板、
11…パッド、
12,12A,13…フィルムシート、
21,22,30…空間、
31…半田ボール、
40,40A…圧力センサ部、
41,44…ケーブル、
42a,42b…コネクタ、
43…信号増幅器、
50…装置コントローラ、
50m…内部メモリ、
51…血管脈圧測定処理モジュール、
52…表示部、
53…A/D変換器、
100…脈圧計測システム、
110…脈圧計測部本体、
120…信号中継部、
210…脈波血圧計本体、
211a,211b…コネクタ、
220…MEMS圧力センサ、
220h…圧力検知用空洞孔。
Claims (9)
- ダイアフラムの圧力検出面側に第1の空間を有し、上記第1の空間に対面する圧力検出面を用いて圧力の検出を行うダイアフラムを有し、検出した圧力に対応する電気信号を出力するMEMS圧力センサと、
上記MEMS圧力センサを支持して被測定部に接触して載置される第1のフィルムシートであって、上記第1の空間に連通しかつ上記第1の空間よりも大きな、上記圧力検出面に平行な方向のサイズを有する第2の空間を有する第1のフィルムシートとを備えるMEMS圧力センサ装置であって、
上記MEMS圧力センサ装置を上記被測定部に位置決めするために上記圧力検出面に平行な方向のサイズを有する第3の空間を有する第2のフィルムシートであって、上記MEMS圧力センサ装置を上記被測定部に載置する前に、上記被測定部の部位が上記第3の空間に位置するように載置するための第2のフィルムシートをさらに備えたことを特徴とするMEMS圧力センサ装置。 - 上記MEMS圧力センサ装置を上記第2のフィルムシートを介して上記被測定部に載置したときに上記第1の空間、上記第2の空間及び第3の空間が密閉されて密閉空間となり、上記被測定部の圧力が上記第1の空間、上記第2の空間及び上記第3の空間を介して上記MEMS圧力センサのダイアフラムに伝達されて上記MEMS圧力センサが圧力の検出を行うことを特徴とする請求項1記載のMEMS圧力センサ装置。
- 上記第1の空間、上記第2の空間及び第3の空間はそれぞれ、上記ダイアフラムの圧力検出面に実質的に平行な底面を有し、かつ互いに同軸である実質的に円筒形状又は楕円筒形状を有することを特徴とする請求項1又は2記載のMEMS圧力センサ装置。
- 上記第3の空間の底面の直径は上記第2の空間の底面の直径よりも大きいことを特徴とする請求項1~3のうちのいずれか1つに記載のMEMS圧力センサ装置。
- 上記第2の空間の底面の直径は上記第1の空間の底面の直径よりも大きいことを特徴とする請求項1~4のうちのいずれか1つに記載のMEMS圧力センサ装置。
- 上記第1及び第2のフィルムシートは粘着性シートであることを特徴とする請求項1~5のうちのいずれか1つに記載のMEMS圧力センサ装置。
- 請求項1~6のうちのいずれか1つに記載のMEMS圧力センサ装置と、
上記MEMS圧力センサ装置からの電気信号に基づいて、予め計測された電気信号レベルと圧力値との関係を参照して圧力値を算出して出力する圧力計測部とを備えることを特徴とする圧力計測システム。 - 上記MEMS圧力センサ装置の第3の空間は上記被測定部の血管に、圧力検出可能に近接して設けられ、
上記圧力計測部は上記圧力値である脈圧値を算出して出力することを特徴とする請求項7記載の圧力計測システム。 - ダイアフラムの圧力検出面側に第1の空間を有し、上記第1の空間に対面する圧力検出面を用いて圧力の検出を行うダイアフラムを有し、検出した圧力に対応する電気信号を出力するMEMS圧力センサと、
上記MEMS圧力センサを支持して被測定部に接触して載置される第1のフィルムシートであって、上記第1の空間に連通しかつ上記第1の空間よりも大きな、上記圧力検出面に平行な方向のサイズを有する第2の空間を有する第1のフィルムシートとを備えるMEMS圧力センサ装置の位置決め方法であって、
上記圧力検出面に平行な方向のサイズを有する第3の空間を有する第2のフィルムシートを用いて、上記被測定部の部位が上記第3の空間に位置するように、上記第2のフィルムシートを上記被測定部の部位上に載置するステップと、
次いで、上記第1のフィルムシートを有するMEMS圧力センサを、上記第2の空間が上記第3の空間に位置するように上記第2のフィルムシート上に載置することで、上記MEMS圧力センサ装置を上記被測定部に位置決めするステップとを含むことを特徴とするMEMS圧力センサ装置の位置決め方法。
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