WO2016058193A1 - 治疗亚健康的中药组合物及其制备方法 - Google Patents

治疗亚健康的中药组合物及其制备方法 Download PDF

Info

Publication number
WO2016058193A1
WO2016058193A1 PCT/CN2014/088931 CN2014088931W WO2016058193A1 WO 2016058193 A1 WO2016058193 A1 WO 2016058193A1 CN 2014088931 W CN2014088931 W CN 2014088931W WO 2016058193 A1 WO2016058193 A1 WO 2016058193A1
Authority
WO
WIPO (PCT)
Prior art keywords
parts
weight
chinese medicine
drug solution
medicine composition
Prior art date
Application number
PCT/CN2014/088931
Other languages
English (en)
French (fr)
Inventor
张贯京
陈兴明
葛新科
王海荣
张少鹏
方静芳
程金兢
梁艳妮
周荣
徐之艳
周亮
徐菊红
付石柱
梁昊原
王家永
毛侃琅
蒋兴菊
杨青蓝
刘义
肖应芬
何晓霞
吴彬霞
郑慧华
唐小浪
张世导
李潇云
侯云超
赵学明
赵雪竹
刘国勇
Original Assignee
深圳市前海安测信息技术有限公司
深圳市易特科信息技术有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市前海安测信息技术有限公司, 深圳市易特科信息技术有限公司 filed Critical 深圳市前海安测信息技术有限公司
Publication of WO2016058193A1 publication Critical patent/WO2016058193A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Definitions

  • the invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating sub-health and a preparation method thereof.
  • Sub-health refers to a state of low physiological function between health and disease, which is manifested by symptoms of decreased vitality, decreased function and adaptability within a certain period of time.
  • the main object of the present invention is to solve the technical problems of slow onset, poor therapeutic effect, inability to cure sub-health, and high treatment cost of the existing sub-health drugs.
  • the present invention provides a traditional Chinese medicine composition for treating sub-health, wherein the components and parts by weight of the sub-healthy Chinese medicine composition are:
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • Ai Ye 25 ⁇ 30wt parts, Pueraria 55 ⁇ 60wt parts, white peony 45 ⁇ 50wt parts, mint 15 ⁇ 20wt parts, ⁇ 10 ⁇ 15wt parts, jujube 30 ⁇ 40wt parts, acanthopanax 45 ⁇ 50 Parts by weight, 55 ⁇ 60 parts by weight of cassia twig, 25 ⁇ 30 parts by weight of scutellaria, 25 ⁇ 30 parts by weight of dodder, 25 ⁇ 30 parts by weight of ginseng leaves and 15 ⁇ 20 parts by weight of chuanxiong.
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • the present invention also provides a method for preparing the above-mentioned traditional Chinese medicine composition for treating sub-health, comprising the following steps:
  • the components are ground into a powder and then placed in a cotton bag;
  • the drug solution A, the drug solution B, and the drug solution C are mixed to prepare a drug solution D for use.
  • the method for preparing the sub-healthy Chinese medicine composition further comprises the following steps:
  • the drug solution D is placed in a centrifuge at 3500 ⁇ 5000 Centrifuge at rpm for 30 to 60 minutes to obtain a liquid E that is divided into a pale yellow transparent layer and a dark layer;
  • the dark layer liquid in the liquid E is taken out and sealed and packaged for use.
  • the method for preparing the sub-healthy Chinese medicine composition further comprises the following steps:
  • the drug solution D is directly decocted in a container, and the drug solution D is volatilized to obtain a drug solution E', the drug solution E' capacity is 2/3 of the capacity of the drug solution D;
  • the drug solution E' is taken out and sealed and packaged for use.
  • the cotton bag is placed in normal temperature water to soak, and boil the water at room temperature, and then boiled, and the liquid medicine A is poured out into the standby step, the amount of the normal temperature water is 7 of the total weight of each component. ⁇ 10 times, the soaking time is 25 ⁇ 35 minutes, the normal temperature water is boiled by martial arts and then transferred to a simmering simmer, wherein the simmering time is 5-8 minutes.
  • the soaking time is 30 minutes and the simmering time is 5 minutes.
  • the normal temperature water is added to the cotton bag, and the water is boiled at room temperature, and then boiled, and the liquid B is poured out into the standby step, and the amount of the normal temperature water is 7 to 10 times the total weight of each component.
  • the normal temperature water is boiled by martial arts and then tempered to a simmer, wherein the simmering time is 10 to 12 minutes.
  • the simmering time is 10 minutes.
  • the water bag is soaked in a normal temperature water and boiled at room temperature, and then boiled, and the liquid C is poured out into a standby step, wherein the amount of the normal temperature water is 7 to 10 of the total weight of each component. Times, the room temperature water is boiled to a simmer and boiled, and the simmering time is 15 to 18 minutes.
  • the simmering time is 15 minutes.
  • the invention relates to a traditional Chinese medicine composition for treating sub-health and a preparation method thereof, wherein the traditional Chinese medicine composition adopts a common traditional Chinese medicine, has low cost and quick onset, and is usually effective within one month, and the traditional Chinese medicine composition is used for treating sub-health.
  • the efficiency is 100%, the cure rate is 95%, the treatment effect is exact, and the curative effect can be achieved.
  • the preparation method is simple, high in efficiency, and is also beneficial for preservation and extraction of active ingredients of the medicine.
  • the invention provides a traditional Chinese medicine composition for treating sub-health, wherein the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • Ai Ye Antibacterial, antiviral, antiasthmatic, antitussive, expectorant, antiallergic and immune function.
  • Pueraria sweet and slightly spicy, fragrant, cool, and the main spleen and stomach. There is a release of muscles, sun rash, antipyretic effect.
  • spleen deficiency diarrhea fever thirst, attending exogenous fever, strong head and neck pain, measles opacity, warmth thirst, diabetes, alcoholism, chest pain and other symptoms.
  • White peony nourishing blood and softening the liver, slowing the pain, and collecting the sweat.
  • Mint It has the effect of dispelling wind and cooling, clearing the head, sharpening the throat, diarrhea and relieving depression.
  • ⁇ It is used for urination, edema, etc. For spleen deficiency diarrhea, bring down. It is used to sip cough, phlegm and dampness, and shoulder pain. For palpitations, insomnia and other symptoms.
  • Jujube spleen and stomach, strengthen human immunity, qi and nourish blood, strengthen muscle strength, increase body weight, relieve medicinal properties, calm and soothe the nerves, nourish blood and soothe the nerves, resist allergies, fight cancer and protect the liver.
  • Acanthopanax senticosus It has anti-aging, anti-fatigue, anti-cancer, and pharmacological effects such as regulating nerve, endocrine, cardiovascular function and improving body resistance. Therapeutic dysfunction, impotence, premature ejaculation and other symptoms.
  • Guizhi It treats cold and cold, has the effect of reconciling the camp, and relieving muscle and antiperspirant. It can also warm, chill, and promote blood circulation. Treatment of shoulder and arm pain caused by wind and cold obstruction, poor blood and blood.
  • Astragalus Sexually sweet, slightly warm. Return to the lungs, spleen, liver, kidney. It is beneficial to the effect of gas-solid table, sweating and solidification, sore muscles, and water swelling. For the treatment of qi deficiency, moderate gas subsidence, prolonged diarrhea, rectal prolapse, blood in the stool, dysfunction, self-sweating, sputum, ulceration, long-term collapse, blood deficiency, stagnation, internal heat, thirst, chronic nephritis, proteinuria, diabetes, etc.
  • Dodder sweet, warm, nourishing liver and kidney, solid and urinary, fetus, eyesight, diarrhea.
  • Ginseng leaves taste bitter, sweet, cold, return to the lungs, stomach two classics, with "clear lungs, Shengjin, thirst quenching", “compensation with the table, Shengweijin, sputum heat, reduce the virtual fire, benefit the limbs", " Shengjin Runzao, Yifei and Liver, cultivated vitality and other functions.
  • Chuanxiong blood circulation, hurricane pain. Used to calm nerves, head wind headache, symptoms, abdominal pain, chest pain, tingling, swelling, pain, rheumatism and pain.
  • sub-health is also called Chinese medicine biased constitution
  • Chinese medicine dialectic is heart and spleen deficiency, lack of blood and blood, liver qi stagnation
  • treatment is spleen and qi, nourishing the heart and calming the nerves, sparse Liver qi.
  • traditional meaning of the traditional Chinese medicine composition for treating sub-health is as follows: the combination of evacuation and benefit.
  • Astragalus ginseng leaves, acanthopanax senticosus, white peony root, jujube tonic qi and blood; dodder silk warming kidney yang; puerarin, mint lightly evacuated, cassia twig, wormwood, chuanxiong warm and blood circulation, dredge meridians. All kinds of medicines are used together, the evil spirits go, the qi and blood are supplemented; the meridians are profitable, and the whole body is Tongtai.
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • Ai Ye 25 ⁇ 30wt parts, Pueraria 55 ⁇ 60wt parts, white peony 45 ⁇ 50wt parts, mint 15 ⁇ 20wt parts, ⁇ 10 ⁇ 15wt parts, jujube 30 ⁇ 40wt parts, acanthopanax 45 ⁇ 50 Parts by weight, 55 ⁇ 60 parts by weight of cassia twig, 25 ⁇ 30 parts by weight of scutellaria, 25 ⁇ 30 parts by weight of dodder, 25 ⁇ 30 parts by weight of ginseng leaves and 15 ⁇ 20 parts by weight of chuanxiong.
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • Ai Ye 27 ⁇ 32 parts by weight, Pueraria 57 ⁇ 62 parts by weight, white peony 47 ⁇ 52 parts by weight, mint 17 ⁇ 22 parts by weight, ⁇ 12 ⁇ 17 parts by weight, jujube 34 ⁇ 44 parts by weight, acanthopanax 47 ⁇ 52 Parts by weight, 57 ⁇ 62 parts by weight of cassia twig, 27 ⁇ 32 parts by weight of scutellaria, 27 ⁇ 32 parts by weight of dodder, 27 ⁇ 32 parts by weight of ginseng leaves and 17 ⁇ 22 parts by weight of chuanxiong.
  • the components and parts by weight of the traditional Chinese medicine composition for treating sub-health are:
  • the invention also provides a preparation method of the above traditional Chinese medicine composition for treating sub-health, comprising the following steps:
  • Each component was ground into a powder and then placed in a cotton bag.
  • the above components are ground into a powder by a grinding device, and the cotton bag is preferably a gauze bag.
  • the simmering time is preferably 10 minutes.
  • the simmering time is preferably 15 minutes.
  • the drug solution D Places the drug solution D in a centrifuge at 3500 ⁇ 5000 Centrifuge at rpm for 30 to 60 minutes to obtain a liquid E which is divided into a pale yellow transparent layer and a dark layer; the dark layer liquid in the liquid E is taken out and sealed and packaged for use.
  • the drug solution D is directly placed in a container to be boiled, and the drug solution D is volatilized to obtain a drug solution E'.
  • the volume of the drug solution E' is 2/3 of the volume of the drug solution D; the drug solution E' is taken out and sealed and packaged for use.
  • the above packaging method adopts a bagging method, and the bag is sealed after sealing.
  • the above preparation method is simple, high in efficiency, and is favorable for preservation and extraction of active ingredients of the medicine.
  • the present invention also provides a method for preparing a traditional Chinese medicine composition for treating sub-health, comprising the following steps:
  • Ai leaves, puerarin, white peony root, medlar, jujube, acanthopanax senticosus, cassia twig, scutellaria, medlar, ginseng leaves and chuanxiong are ground into powder and then put into a cotton bag.
  • the mint is not added in this step, and the above components are ground into a powder by a grinding device, and the cotton bag is preferably a gauze bag.
  • the simmering time is preferably 10 minutes.
  • the drug solution D can also be purified and concentrated by centrifugation or distillation, and will not be described herein.
  • the gauze bag containing the powdered traditional Chinese medicine component is placed in a casserole containing 3.045 to 4.350 of normal temperature water for 30 minutes, preferably 3.2 kg of normal temperature water, wherein the medicinal material absorbs about 800 g of water;
  • the liquid D prepared above is poured into a bathtub or a bathtub.
  • the water temperature is generally controlled at about 40 degrees Celsius, and the maximum temperature is not more than 42 degrees Celsius.
  • the patient is placed in a bathtub or a bathtub and immersed in the whole body.
  • the medicated bath is once a day, about 30 minutes each time. Under normal circumstances, it is not less than three times a week. It only takes one month to be effective.
  • the drug solution D is purified and concentrated:
  • all the dark layer liquid in the above prepared liquid E is poured into a bathtub or a bathtub.
  • the water temperature is generally controlled at about 40 degrees Celsius, and the maximum temperature is not more than 42 degrees Celsius.
  • the patient is placed in a bathtub or a bathtub. Immerse the whole body.
  • the medicated bath is once a day, about 30 minutes each time. Under normal circumstances, it is not less than three times a week. It only takes one month to be effective.
  • the drug solution D is purified and concentrated:
  • the volume of the drug solution E' is 2/3 of the capacity of the drug solution D, assuming that the normal temperature water added each time is 3.2 Kg. Finally, the drug solution E' is about 5.5. Kg, 5500ml, is bagged in 500ml, a total of 11 bags, and then sealed for use.
  • the drug solution E' obtained by the evaporation method has a lower concentration of the dark layer liquid of the drug solution E obtained by the centrifugation method of the above-mentioned Example 2, and the preparation time is long, but the utilization rate of the drug is high.
  • the water temperature is generally controlled at about 40 degrees Celsius, and the maximum temperature is not more than 42 degrees Celsius.
  • the patient is placed in a bathtub or a bathtub and immersed in the whole body.
  • the medicated bath is once a day, about 30 minutes each time. Under normal circumstances, it is not less than three times a week. It only takes one month to be effective.
  • the medicated bath prepared by using the traditional Chinese medicine composition of the above examples is used for medicated bath treatment, and the medicated bath treatment method has the following advantages:
  • the drug directly enters the blood through the skin, ensuring the drug's medicinal properties, so it is quicker than the internal drug, and does not have to adhere to it every day. Under normal circumstances, it can be used three times a week, just one month. See the obvious effect.
  • the use of skin secretion, absorption, penetration and other functions can enable drugs through the skin surface absorption, stratum corneum penetration and dermal layer transport, into the blood circulation directly to the lesions, to ensure the full absorption of drugs, but also to avoid the drug on the stomach Intestinal damage.
  • Case 1 Zhao, male, 50 years old, the body has always been bad, the patient complained of general malaise, dizziness, fatigue, insomnia and more dreams, after repeated treatment of medication is invalid.
  • the six veins were weak, and the shuang was slightly chord.
  • the patient was pale and the tongue was slightly slippery.
  • the traditional Chinese medicine composition of the present invention is used for one week of bathing, and the patient is diagnosed on November 1st. After consciously taking the medicine, the cold feeling is improved, the mental recovery is resumed, and the dizziness is relieved; the medication is continued for one week, and the diagnosis is made on November 7th, and the condition is greatly reduced after the self-reporting medicine.
  • the spirit is better, the head is not dizzy; after a week of medication, there is no discomfort so far.
  • Case 5 Lumou, female, 29 years old, checked by the hospital for blood pressure, heart rate, triglyceride, cholesterol, blood sugar, all indicators are normal, patients feel loss of appetite, insomnia, dreams, doubts, fatigue, headache, body weight The waist and knees are sore and the diagnosis is sub-health.
  • the symptoms basically disappeared after one week, and various adverse symptoms completely disappeared after 15 days.
  • the effective rate of the traditional Chinese medicine composition for treating sub-health is 100%, and the cure rate is 95%.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

一种治疗亚健康的中药组合物及其制备方法，该治疗亚健康的中药组合物的组分及重量份为：艾叶25－35重量份，葛根55－65重量份，白芍45－55重量份，薄荷15－25重量份，茯苓10－20重量份，大枣30－50重量份，刺五加45－55重量份，桂枝55－65重量份，黄芪25－35重量份，菟丝子25－35重量份，人参叶25－35重量份以及川芎15－25重量份。

Description

治疗亚健康的中药组合物及其制备方法
技术领域
本发明涉及中药领域，尤其涉及一种治疗亚健康的中药组合物及其制备方法。
背景技术
亚健康是指介于健康和疾病之间的一种生理功能低下的状态，表现为一定时间内活力下降、功能和适应能力减退的症状。
现有的一些治疗亚健康的药物，往往起效慢、疗效不确切，无法完全治愈亚健康，或者使用价格十分昂贵的原材料来达到治疗效果的目的，由此导致治疗成本高，普通的家庭难以承受，只能“望药兴叹”。
发明内容
本发明的主要目的在于解决现有的治疗亚健康的药物的起效慢、治疗效果差、无法根治亚健康以及治疗成本高的技术问题。
为实现上述目的，本发明提供一种治疗亚健康的中药组合物，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶25~35重量份，葛根55~65重量份，白芍45~55重量份，薄荷15~25重量份，茯苓10~20重量份，大枣30~50重量份，刺五加45~55重量份，桂枝55~65重量份，黄芪25~35重量份，菟丝子25~35重量份，人参叶25~35重量份以及川芎15~25重量份。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶25~30重量份，葛根55~60重量份，白芍45~50重量份，薄荷15~20重量份，茯苓10~15重量份，大枣30~40重量份，刺五加45~50重量份，桂枝55~60重量份，黄芪25~30重量份，菟丝子25~30重量份，人参叶25~30重量份以及川芎15~20重量份。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶30~35重量份，葛根60~65重量份，白芍50~55重量份，薄荷20~25重量份，茯苓15~20重量份，大枣40~50重量份，刺五加50~55重量份，桂枝60~65重量份，黄芪30~35重量份，菟丝子30~35重量份，人参叶30~35重量份以及川芎15~25重量份。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶30重量份，葛根60重量份，白芍50重量份，薄荷20重量份，茯苓15重量份，大枣40重量份，刺五加50重量份，桂枝60重量份，黄芪30重量份，菟丝子30重量份，人参叶30重量份以及川芎20重量份。
此外，为实现上述目的，本发明还提供一种上述治疗亚健康的中药组合物的制备方法，包括如下步骤：
将各组分研磨成粉状后装入棉袋中；
将棉袋置入常温水中浸泡，并煮沸常温水，然后再煎煮，并将药液A倒出备用；
加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液B倒出备用；
再次加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液C倒出备用；
将所述药液A、药液B以及药液C混合制得药液D备用。
优选地，所述治疗亚健康的中药组合物的制备方法还包括如下步骤：
将所述药液D置于离心机中，在3500~5000 rpm转速下离心30~60分钟，得到分为淡黄色透明层和深色层的药液E；
将药液E中深色层液体取出，密封包装备用。
优选地，所述治疗亚健康的中药组合物的制备方法还包括如下步骤：
将所述药液D直接放在容器中煎煮，让药液D挥发得到药液E’，所述药液E’容量为所述药液D容量的2/3；
取出药液E’，密封包装备用。
优选地，所述将棉袋置入常温水中浸泡，并煮沸常温水，然后再煎煮，并将药液A倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，浸泡时间为25~35分钟，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为5~8分钟。
优选地，所述浸泡时间为30分钟，所述文火煎煮时间为5分钟。
优选地，所述加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液B倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为10~12分钟。
优选地，所述文火煎煮时间为10分钟。
优选地，所述再次加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液C倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为15~18分钟。
优选地，所述文火煎煮时间为15分钟。
本发明的治疗亚健康的中药组合物及其制备方法，所述中药组合物采用普通的中药药材，成本低，起效快，通常一个月内明显见效，采用该中药组合物治疗亚健康的有效率为100%，治愈率达到95%，治疗效果确切，可以达到根治的疗效。所述制备方法简单、效率高、且还有利于药物有效成分的保存及提取。
具体实施方式
应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
本发明提供一种治疗亚健康的中药组合物，述治疗亚健康的中药组合物的组分及重量份为：
艾叶25~35重量份，葛根55~65重量份，白芍45~55重量份，薄荷15~25重量份，茯苓10~20重量份，大枣30~50重量份，刺五加45~55重量份，桂枝55~65重量份，黄芪25~35重量份，菟丝子25~35重量份，人参叶25~35重量份以及川芎15~25重量份。
其中，该治疗亚健康的中药组合物的各组分的方解为：
艾叶：抗菌、抗病毒、平喘、镇咳、祛痰、抗过敏以及增强免疫功能。
葛根：味甘微辛，气清香，性凉，主入脾胃经。有发表解肌，升阳透疹，解热生津之功效。用于治疗脾虚泄泻、热病口渴、主治外感发热，头颈痛强，麻疹透发不畅，温病口渴，消渴，酒毒，胸痹心痛等病症。
白芍：养血柔肝，缓中止痛，敛阴收汗。
薄荷：具有疏风散热，清头目，利咽喉，透疹，解郁的功效。
茯苓：用于小便不利，水肿等。用于脾虚泄泻，带下。用于痰饮咳嗽，痰湿入络，肩背酸痛。用于心悸，失眠等症。
大枣：健脾益胃、增强人体免疫力、补气养血、增强肌力、增加体重、缓和药性、镇静安神、养血安神、抗过敏、抗癌、保护肝脏。
刺五加：具有抗衰老、抗疲劳、抗癌，和调节神经、内分泌、心血管功能，提高机体抵抗能力等药理作用。治疗性功能减退、阳痿早泄等症。
桂枝：治疗风寒感冒，有调和营卫，解肌止汗的作用。还能温经、祛风寒、活血通络。治疗因风寒阻络、气血不畅所致的肩臂疼痛。
黄芪：性味甘，微温。归经、归肺、脾、肝、肾经。有益气固表、敛汗固脱、托疮生肌、利水消肿之功效。用于治疗气虚乏力，中气下陷，久泻脱肛，便血崩漏，表虚自汗，痈疽难溃，久溃不敛，血虚萎黄，内热消渴，慢性肾炎，蛋白尿，糖尿病等。
菟丝子：味甘，性温，滋补肝肾，固精缩尿，安胎，明目，止泻。
人参叶：味苦、甘、寒，归肺、胃二经，具有“清肺，生津，止渴”、“补中带表，生胃津，祛暑气，降虚火，利四肢头目”、“生津润燥，益肺和肝，培补元气”等功能。 能提高神经在活动过程的灵活性。可改善睡眠和情绪，提高脑力、体力等人体机能，有显著的抗疲劳、利尿和抗辐射作用。
川芎：活血行气，祛风止痛。用于安抚神经，正头风头痛，症瘕腹痛，胸胁刺痛，跌扑肿痛，风湿痹痛。
本发明治疗亚健康的中药组合物的药理为：亚健康也叫中医偏颇体质，中医辩证为心脾二虚，气血不足，肝气郁滞，治法为健脾益气，养心安神，疏肝理气。本发明治疗亚健康的中药组合物的方义为：疏散补益相结合。黄芪、人参叶、刺五加、白芍、大枣补益气血；菟丝子温补肾阳；葛根、薄荷轻利疏散，桂枝、艾叶、川芎温经活血，疏通经脉。诸药合用，外邪去，气血得补；经脉通利，周身通泰。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶25~30重量份，葛根55~60重量份，白芍45~50重量份，薄荷15~20重量份，茯苓10~15重量份，大枣30~40重量份，刺五加45~50重量份，桂枝55~60重量份，黄芪25~30重量份，菟丝子25~30重量份，人参叶25~30重量份以及川芎15~20重量份。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶27~32重量份，葛根57~62重量份，白芍47~52重量份，薄荷17~22重量份，茯苓12~17重量份，大枣34~44重量份，刺五加47~52重量份，桂枝57~62重量份，黄芪27~32重量份，菟丝子27~32重量份，人参叶27~32重量份以及川芎17~22重量份。
优选地，所述治疗亚健康的中药组合物的组分及重量份为：
艾叶30~35重量份，葛根60~65重量份，白芍50~55重量份，薄荷20~25重量份，茯苓15~20重量份，大枣40~50重量份，刺五加50~55重量份，桂枝60~65重量份，黄芪30~35重量份，菟丝子30~35重量份，人参叶30~35重量份以及川芎15~25重量份。
本发明还提供一种上述治疗亚健康的中药组合物的制备方法，包括如下步骤：
（1）将各组分研磨成粉状后装入棉袋中。其中，上述组分通过研磨装置研磨成粉状，棉袋优选为纱布袋。
（2）将棉袋置入各组分总重量的7~10倍用量的常温水中浸泡25~35分钟，并采用武火煮沸常温水，然后再调至文火煎煮5~8分钟，并将药液A倒出备用。其中，采用常用的煎熬中药的容器（砂锅或搪瓷容器）盛放常温水，棉袋放入该容器中并浸泡在常温水中，浸泡时间优选为30分钟，文火煎煮时间优选为5分钟。
（3）加入各组分总重量的7~10倍用量的常温水浸泡棉袋，并用武火煮沸常温水，然后再调至文火煎煮10~12分钟，将药液B倒出备用。其中，文火煎煮时间优选为10分钟。
（4）再加入各组分总重量的7~10倍用量的常温水浸泡棉袋，并用武火煮沸常温水，然后再调至文火煎煮15~18分钟，将药液C倒出备用。其中，文火煎煮时间优选为15分钟。
（5）将药液A、药液B和药液C混合制得药液D备用。
（6）将药液D置于离心机中，在3500~5000 rpm转速下离心30~60分钟，得到分为淡黄色透明层和深色层的药液E；将药液E中的深色层液体取出，密封包装备用。或者，将药液D直接放在容器中煎煮，让药液D挥发得到药液E’，药液E’容量为药液D容量的2/3；取出药液E’，密封包装备用。其中，上述包装方式采用装袋方式，装袋后封口密封。
上述制备方法简单、效率高、有利于药物有效成分的保存及提取。
另外，本发明还提供一种上述治疗亚健康的中药组合物的制备方法，包括如下步骤：
（1）将艾叶、葛根、白芍、茯苓、大枣、刺五加、桂枝、黄芪、菟丝子、人参叶以及川芎研磨成粉状后装入棉袋中。其中，薄荷在此步骤中不加入，上述组分通过研磨装置研磨成粉状，棉袋优选为纱布袋。
（2）将棉袋置入各组分（含薄荷）总重量的7~10倍用量的常温水中浸泡25~35分钟，并采用武火煮沸常温水，然后再调至文火煎煮5~8分钟，并将药液A倒出备用。其中，采用常用的煎熬中药的容器（砂锅或搪瓷容器）盛放常温水，棉袋放入该容器中并浸泡在常温水中，浸泡时间优选为30分钟，文火煎煮时间优选为5分钟。
（3）加入各组分（含薄荷）总重量的7~10倍用量的常温水浸泡棉袋，并用武火煮沸常温水，然后再调至文火煎煮10~12分钟，将药液B倒出备用。其中，文火煎煮时间优选为10分钟。
（4）再加入各组分（含薄荷）总重量的7~10倍用量的常温水浸泡棉袋，并用武火煮沸常温水，加入薄荷，然后再调至文火煎煮15~18分钟，将药液C倒出备用。其中，文火煎煮时间优选为15分钟。
（5）将药液A、药液B和药液C混合制得药液D备用。药液D也可以采用离心或者蒸馏的方式进行提纯浓缩，在此不作赘述。
以下通过实施例对本发明的治疗亚健康的中药组合物、制备方法及其使用方法做详细说明：
实施例1
将艾叶30g，葛根60g，白芍50g，薄荷20g，茯苓15g，大枣40g，刺五加50g，桂枝60g，黄芪30g，菟丝子30g，人参叶30g以及川芎20g（共计435g）通过研磨装置碾磨成粉末状后装入纱布袋中；
将装有粉末状中药组分的纱布袋置入盛有3.045~4.350的常温水的砂锅中浸泡30分钟，优选地加入3.2Kg的常温水，其中，药材大约会吸收800g左右的水；
先用武火将常温水煮沸，然后再调至文火煎煮5分钟后，关火并将药液A倒出备用；
向砂锅中加入3.045~4.350的常温水，优选地加入3.2Kg的常温水，用武火将常温水煮沸，文火煎煮10分钟后，关火并将药液B倒出备用，3.2Kg的常温水基本不会被药物吸收；
再向砂锅中加入3.045~4.350的常温水，优选地加入3.2Kg的常温水，用武火将常温水煮沸，文火煎煮15分钟后，关火并将药液C倒出备用，将药液A、药液B和药液C混合均匀得到药液D备用，约为8.8Kg；
使用时，将上述制备的药液D全部倒入浴缸或澡盆，加入适量热水后，水温一般控制在40摄氏度左右，最高不要超过42摄氏度，患者卧入浴缸或澡盆并浸没全身。药浴每天一次，每次30分钟左右即可，一般情况下每周不低于三次，只需坚持一个月就可明显见效。治疗过程中，煮好药液之后药包（装有药材的纱布袋）不要丢弃，药浴时还可以使用其擦洗身体，尤其是病变患处，可以增加局部的药物浓度。
实施例2
在上述实施例1制备得到的8.8Kg的药液D基础上，为了便于药液的包装和封存，对药液D进行提纯浓缩：
将药液D趁热置于离心机中，在3500~5000 rpm转速下离心30~60分钟，得到分为淡黄色透明层和深色层的药液E，将药液E中的深色层液体取出，假设每次加入的常温水为3.2Kg，则最后得到药液E中的深色层液体约为4.4 Kg，即4400ml，以500ml为一份装袋，共9包，然后封口备用。
使用时，将上述制备的药液E中的深色层液体全部倒入浴缸或澡盆，加入适量热水后，水温一般控制在40摄氏度左右，最高不要超过42摄氏度，患者卧入浴缸或澡盆并浸没全身。药浴每天一次，每次30分钟左右即可，一般情况下每周不低于三次，只需坚持一个月就可明显见效。治疗过程中，煮好药液之后药包（装有药材的纱布袋）不要丢弃，药浴时还可以使用其擦洗身体，尤其是病变患处，可以增加局部的药物浓度。
实施例3
在上述实施例1制备得到的8.8Kg的药液D基础上，为了便于药液的包装和封存，对药液D进行提纯浓缩：
将药液D直接放在容器中煎煮，让药液D挥发得到药液E’，药液E’容量为药液D容量的2/3，假设每次加入的常温水为3.2Kg，则最后得到药液E’约为5.5 Kg，即5500ml，以500ml为一份装袋，共11包，然后封口备用。
本实施例通过蒸发方法得到的药液E’比上述实施例2通过离心方法得到的药液E的深色层液体的浓度低，制备时间久，但其对药物的利用率高。
使用时，将上述制备的药液E’全部倒入浴缸或澡盆，加入适量热水后，水温一般控制在40摄氏度左右，最高不要超过42摄氏度，患者卧入浴缸或澡盆并浸没全身。药浴每天一次，每次30分钟左右即可，一般情况下每周不低于三次，只需坚持一个月就可明显见效。治疗过程中，煮好药液之后药包（装有药材的纱布袋）不要丢弃，药浴时还可以用它擦洗身体，尤其是病变患处，可以增加局部的药物浓度。
使用上述实施例的中药组合物制备的药液进行药浴治疗，该药浴治疗方式具有如下优点：
1、通过提供舒适的外部环境，促进血液循环，使得经络畅通，进而消除身体疲劳，缓解精神紧张；再加上药物对身体内部机能的调整，通过内外结合的方式，全面的改善人体失眠、心绪不宁、注意力不集中、精神萎靡、食欲不振、健忘等亚健康症状。
2、通过药浴的方式使得药物直接通过皮肤进入血液，保证了药物的药性，故较之内服药见效快，且不必每天坚持，一般情况下每周三次即可，只需坚持一个月就可看到明显效果。
3、利用皮肤的分泌、吸收、渗透等功能，能够使药物通过皮肤表层吸收、角质层渗透和真皮层转运，进入血液循环直达病灶，保证了药物的充分吸收，也避免了药物内服时对胃肠的损伤。
本具体实施方式中的治疗亚健康的中药组合物的疗效通过下述的典型病例做进一步说明：
病例1：赵某，男，50岁，身体平时一直不好，病人自诉感觉全身不适，头晕乏力，失眠多梦，经多次医治用药无效。10月20日来诊，六脉弱，双关稍弦，观病人面色苍白，舌苔稍滑。使用本发明的中药组合物泡浴一周，11月1日来诊，自觉用药后，冷感好转，精神恢复，头晕减轻；继续用药一周，11月7日来诊，自诉药后病情大减，精神好转，头不晕；继续用药一周后，至今无不适感。
病例2：贺某，女，42岁，平时易疲劳，记忆力较差，注意力不集中，经常易患感冒咳嗽，使用本发明的中药组合物泡浴3次，症状明显改善，后继续用药10次后，感觉神清气爽，精神倍增。
病例3：范某，男，56岁，江苏人，自诉精神压力大，平时失眠多梦，腰酸腿软，有抑郁情绪及肾虚，眼老花严重脱发。此种状况持续了3年，期间有经过中西医各方面的治疗，疗效不佳。诊见：神疲、面色无华，发须花白，寸脉弦，尺脉弱，舌体小，少苔。使用本发明的中药组合物泡浴1周后，睡眠有所改善，腰腿酸软有轻微好转，使用本发明的中药组合物泡浴1个月后，睡眠明显好转，精神也较之以前饱满，腰酸腿软明显改善。
病例4：张某，38岁，深圳某公司老板，平时忙于工作，几乎从不健身。近一年来，因工作压力大，记忆力明显减退，疲乏无力，失眠多梦， 期间有经过西医治疗，疗效不佳。诊见：脸色晦暗，气短乏力，声音低沉，脉滑，尺脉稍弱，舌微黄腻。使用本发明的中药组合物泡浴当天，自诉疲劳当即减轻，使用本发明的中药组合物泡浴1月后，脸色逐渐转红润，声音洪亮，精神饱满。
病例5：吕某，女，29岁，经医院检查血压、心率、甘油三脂、胆固醇、血糖各项指标均正常，患者感觉食欲不振、失眠多梦、多疑虑、乏力、头痛、体形偏胖、腰膝酸软，诊断为亚健康。使用本发明的中药组合物泡浴，一周后症状基本消失，15天后各种不良症状完全消失。
利用本发明的中药组合物治疗亚健康，经过120例亚健康患者的治疗，该中药组合物治疗亚健康的有效率为100%，治愈率达到95%。
以上仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书内容所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。

Claims (15)

  1. 一种治疗亚健康的中药组合物，所述治疗亚健康的中药组合物的组分及重量份为：
    艾叶25~35重量份，葛根55~65重量份，白芍45~55重量份，薄荷15~25重量份，茯苓10~20重量份，大枣30~50重量份，刺五加45~55重量份，桂枝55~65重量份，黄芪25~35重量份，菟丝子25~35重量份，人参叶25~35重量份以及川芎15~25重量份。
  2. 如权利要求1所述的治疗亚健康的中药组合物，所述治疗亚健康的中药组合物的组分及重量份为：
    艾叶25~30重量份，葛根55~60重量份，白芍45~50重量份，薄荷15~20重量份，茯苓10~15重量份，大枣30~40重量份，刺五加45~50重量份，桂枝55~60重量份，黄芪25~30重量份，菟丝子25~30重量份，人参叶25~30重量份以及川芎15~20重量份。
  3. 如权利要求1所述的治疗亚健康的中药组合物，所述治疗亚健康的中药组合物的组分及重量份为：
    艾叶30~35重量份，葛根60~65重量份，白芍50~55重量份，薄荷20~25重量份，茯苓15~20重量份，大枣40~50重量份，刺五加50~55重量份，桂枝60~65重量份，黄芪30~35重量份，菟丝子30~35重量份，人参叶30~35重量份以及川芎15~25重量份。
  4. 如权利要求1所述的治疗亚健康的中药组合物，所述治疗亚健康的中药组合物的组分及重量份为：
    艾叶30重量份，葛根60重量份，白芍50重量份，薄荷20重量份，茯苓15重量份，大枣40重量份，刺五加50重量份，桂枝60重量份，黄芪30重量份，菟丝子30重量份，人参叶30重量份以及川芎20重量份。
  5. 一种如权利要求1所述的治疗亚健康的中药组合物的制备方法，包括如下步骤：
    将各组分研磨成粉状后装入棉袋中；
    将棉袋置入常温水中浸泡，并煮沸常温水，然后再煎煮，并将药液A倒出备用；
    加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液B倒出备用；
    再次加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液C倒出备用；
    将所述药液A、药液B以及药液C混合制得药液D备用。
  6. 如权利要求5所述的治疗亚健康的中药组合物的制备方法，还包括如下步骤：
    将所述药液D置于离心机中，在3500~5000 rpm转速下离心30~60分钟，得到分为淡黄色透明层和深色层的药液E；
    将药液E中深色层液体取出，密封包装备用。
  7. 如权利要求5所述的治疗亚健康的中药组合物的制备方法，还包括如下步骤：
    将所述药液D直接放在容器中煎煮，让药液D挥发得到药液E’，所述药液E’容量为所述药液D容量的2/3；
    取出药液E’，密封包装备用。
  8. 如权利要求5所述的治疗亚健康的中药组合物的制备方法，其中，所述将棉袋置入常温水中浸泡，并煮沸常温水，然后再煎煮，并将药液A倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，浸泡时间为25~35分钟，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为5~8分钟。
  9. 如权利要求8所述的治疗亚健康的中药组合物的制备方法，其中，所述浸泡时间为30分钟，所述文火煎煮时间为5分钟。
  10. 如权利要求5所述的治疗亚健康的中药组合物的制备方法，其中，所述加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液B倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为10~12分钟。
  11. 如权利要求10所述的治疗亚健康的中药组合物的制备方法，其中，所述文火煎煮时间为10分钟。
  12. 如权利要求5所述的治疗亚健康的中药组合物的制备方法，其中，所述再次加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液C倒出备用的步骤中，所述常温水的用量为各组分总重量的7~10倍，所述常温水采用武火煮沸后调至文火煎煮，其中，文火煎煮时间为15~18分钟。
  13. 如权利要求12所述的治疗亚健康的中药组合物的制备方法，其中，所述文火煎煮时间为15分钟。
  14. 一种如权利要求4所述的治疗亚健康的中药组合物的制备方法，包括如下步骤：
    将各组分研磨成粉状后装入棉袋中；
    将棉袋置入常温水中浸泡，并煮沸常温水，然后再煎煮，并将药液A倒出备用；
    加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液B倒出备用；
    再次加入常温水浸泡棉袋，并煮沸常温水，然后再煎煮，将药液C倒出备用；
    将所述药液A、药液B以及药液C混合制得药液D备用。
  15. 如权利要求14所述的治疗亚健康的中药组合物的制备方法，还包括如下步骤：
    将所述药液D置于离心机中，在3500~5000 rpm转速下离心30~60分钟，得到分为淡黄色透明层和深色层的药液E；
    将药液E中深色层液体取出，密封包装备用；或者，
    将所述药液D直接放在容器中煎煮，让药液D挥发得到药液E’，所述药液E’容量为所述药液D容量的2/3；
    取出药液E’，密封包装备用。
PCT/CN2014/088931 2014-10-13 2014-10-20 治疗亚健康的中药组合物及其制备方法 WO2016058193A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410537689.1 2014-10-13
CN201410537689.1A CN104367652B (zh) 2014-10-13 2014-10-13 治疗亚健康的中药组合物及其制备方法

Publications (1)

Publication Number Publication Date
WO2016058193A1 true WO2016058193A1 (zh) 2016-04-21

Family

ID=52547013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2014/088931 WO2016058193A1 (zh) 2014-10-13 2014-10-20 治疗亚健康的中药组合物及其制备方法

Country Status (2)

Country Link
CN (1) CN104367652B (zh)
WO (1) WO2016058193A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109329896A (zh) * 2018-09-28 2019-02-15 袁浩卿 糖浆及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103287A (zh) * 1993-11-29 1995-06-07 陕西省临潼县华清池实业公司 中草药温泉浴液的制备及使用方法
CN1424103A (zh) * 2002-12-27 2003-06-18 王�琦 一种干预亚健康的中药制剂及其制备方法
CN1444953A (zh) * 2002-03-14 2003-10-01 钟凯 一种改善亚健康的保健酒
CN102233086A (zh) * 2010-04-22 2011-11-09 张立中 一种改善亚健康提高男性精气神的保健中药

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1340313A (zh) * 2000-08-30 2002-03-20 周建洪 人参百宝鸡的配方及制作工艺
CN100350961C (zh) * 2003-07-05 2007-11-28 姚克敏 治疗胎漏、胎动不安制剂及其制备方法
CN103006806A (zh) * 2011-09-21 2013-04-03 张洪涛 四季养生浴足液套装
CN103169798A (zh) * 2012-11-13 2013-06-26 黄文珍 治疗梅尼埃病的中药组合物及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103287A (zh) * 1993-11-29 1995-06-07 陕西省临潼县华清池实业公司 中草药温泉浴液的制备及使用方法
CN1444953A (zh) * 2002-03-14 2003-10-01 钟凯 一种改善亚健康的保健酒
CN1424103A (zh) * 2002-12-27 2003-06-18 王�琦 一种干预亚健康的中药制剂及其制备方法
CN102233086A (zh) * 2010-04-22 2011-11-09 张立中 一种改善亚健康提高男性精气神的保健中药

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, no. 2, 30 April 2007 (2007-04-30), pages 103 - 106 *

Also Published As

Publication number Publication date
CN104367652B (zh) 2016-09-07
CN104367652A (zh) 2015-02-25

Similar Documents

Publication Publication Date Title
WO2016058192A1 (zh) 治疗失眠的中药组合物及其制备方法
CN107519285A (zh) 一种纯中药眼贴的配方及其制备方法
WO2016058195A1 (zh) 治疗腰椎间盘突出的中药组合物及其制备方法
CN107007724B (zh) 一种中药保健液及其制备方法
CN103316192A (zh) 一种治疗腰腿痛的中药泡脚液及制备方法
CN105056133A (zh) 一种用于治疗纤维肌痛综合症的中药丸剂及制备方法
CN101829299A (zh) 防治***病的外用贴剂及其制备方法
CN1483423A (zh) 一种治疗恶性肿瘤的中药制剂及其制备方法
WO2016058193A1 (zh) 治疗亚健康的中药组合物及其制备方法
CN105535656A (zh) 一种治疗气阴不足之小儿盗汗的中药组合物
CN105770536A (zh) 用于老年人健康调理的中药保健冲剂及制备方法
WO2016058194A1 (zh) 治疗更年期综合症的中药组合物及其制备方法
CN103989903A (zh) 一种治疗腰肌劳损的中药药膏及制备方法
WO2016058201A1 (zh) 补肾壮阳的中药组合物及其制备方法
CN104324186B (zh) 治疗更年期综合症的中药及其胶囊和膏剂的制备方法
CN103446310B (zh) 一种治疗腰腿痛的中药药浴及其制备方法
CN105381128A (zh) 一种辅助针灸治疗外周神经***中药冲剂及制备方法
CN105999110A (zh) 一种用于治疗女性慢性盆腔疼痛的中药冲剂及制备方法
CN105031235A (zh) 一种灵芝山茱萸养生酒及其制作方法
CN104856524B (zh) 一种降压保健药枕
CN102961697A (zh) 一种治疗慢性风湿性心脏病的中药配方
CN102961461A (zh) 一种治疗病毒性心肌炎的中药组合物
CN102935191B (zh) 一种用于坐骨神经痛的药物及制备方法
CN107648493A (zh) 一种黄精膏及其制备方法
CN102614484B (zh) 一种辅助治疗脑血栓和高血压的洗浴中药及其制备方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14904203

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC

122 Ep: pct application non-entry in european phase

Ref document number: 14904203

Country of ref document: EP

Kind code of ref document: A1