WO2015152255A1 - 支持装置及び検査方法 - Google Patents
支持装置及び検査方法 Download PDFInfo
- Publication number
- WO2015152255A1 WO2015152255A1 PCT/JP2015/060156 JP2015060156W WO2015152255A1 WO 2015152255 A1 WO2015152255 A1 WO 2015152255A1 JP 2015060156 W JP2015060156 W JP 2015060156W WO 2015152255 A1 WO2015152255 A1 WO 2015152255A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- support device
- plane
- columnar member
- columnar
- state
- Prior art date
Links
- 0 C*C1I(*)CCC1 Chemical compound C*C1I(*)CCC1 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
- B01J2219/00662—Two-dimensional arrays within two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/021—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes
- G01N2035/023—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes forming cuvettes in situ, e.g. from plastic strip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0418—Plate elements with several rows of samples
- G01N2035/042—Plate elements with several rows of samples moved independently, e.g. by fork manipulator
Definitions
- the present invention relates to a technical field of a support device capable of supporting a support object such as a biochip and an inspection method using such a support device.
- Patent Document 1 discloses a bioreaction device chip that functions as a well plate.
- a DNA chip is formed on the bottom surface of each well.
- a sample for example, body fluid
- the reaction of the DNA chip with respect to the sample is optically detected by a measuring device such as a scanner.
- the molecular diagnosis of the sample is performed by analyzing the measurement result by the measuring device.
- the measuring device in particular, an observation system such as an objective lens provided in the measuring device
- the DNA chip since the DNA chip is formed on the bottom surface of the well, a technical problem arises that the approach of the measuring device to the DNA chip may be hindered by the side walls constituting the well.
- the DNA chip is preferably formed in a structure such as a well.
- Such a technical problem is not only in the case where a DNA chip is formed on the bottom surface of the well, but also in forming the space while holding an arbitrary holding object (for example, a sample) in the space. The same may occur when it is desired to bring an arbitrary target object (for example, a measuring device) close to a predetermined surface (for example, a surface on which a DNA chip is formed).
- the present invention relates to a support device capable of holding an arbitrary object to be held in a space and allowing an arbitrary object to be approached to a predetermined surface forming the space, and an inspection method using such a support device. It is an issue to provide.
- a support device that solves the above problem includes a columnar first member and an inner surface that can face at least part of the outer surface of the first member, and the first member is disposed in a cylinder defined by the inner surface.
- a cylindrical second member into which at least a part is inserted, and the state of the first and second members can transition from the first state to the second state, and the first state is A predetermined space surrounded by at least a part of the inner surface of the second member and an end surface on one side of the first member different from the outer surface is secured, and the second state includes the first Including a state in which the second member moves relative to the first member toward the other side opposite to the one side with respect to the positions of the first and second members in one state. .
- An inspection method for solving the above-described problem includes a columnar first member and an inner surface that can face at least a part of the outer surface of the first member, and the first member is disposed in a cylinder defined by the inner surface.
- At least one of the first and second members is moved so that the second member moves relative to the first member toward the other side opposite to the one side, At least one of the first and second members After moving towards, approach the measuring device on the end face of one side of the first member.
- the top view of the first columnar member observed from the + Z side, the IV-IV ′ sectional view of the first columnar member, the side view of the first columnar member observed from the + Y side, and the IV-IV of the first columnar member 'It is a sectional view enlarging the vicinity of the welding member in the sectional view.
- a plan view of the second columnar member observed from the + Z side, a VV ′ sectional view of the second columnar member, a side view of the second columnar member observed from the + Y side, and a first view observed from the ⁇ Z side It is a top view of one columnar member.
- the plan view of the cylindrical member observed from the + Z side, the VI-VI ′ sectional view of the cylindrical member, the side view of the cylindrical member observed from the + Y side, and the VI-VI ′ sectional view of the cylindrical member It is sectional drawing which expanded the inner surface vicinity.
- FIG. 10A is a plan view and a cross-sectional view of XVIII-XVIII ′ showing a support device of a ninth embodiment, which is observed from the + Z side. It is sectional drawing which shows the cross section along the XZ plane of the 1st columnar member with which a columnar member is provided, and a 2nd columnar member.
- Plan view of movable member observed from + Z side, sectional view of movable member XX (1) -XX (1) ', sectional view of movable member XX (2) -XX (2)', and projection formed It is an enlarged view of the 1st surface made.
- Plan view of rubber film observed from + Z side, rubber film fixed to columnar member is shown together with columnar member, cross-sectional view along XZ plane, rubber film fixed to columnar member is shown together with columnar member, + Z side
- movement (mainly operation
- each of the X-axis direction and the Y-axis direction is a horizontal direction (that is, a predetermined direction in the horizontal plane), and the Z-axis direction is a vertical direction (that is, a direction orthogonal to the horizontal plane). Yes, in the vertical direction).
- Support device 1 of the first embodiment The support device 1 according to the first embodiment will be described with reference to FIGS. Below, for convenience of explanation, the configuration of the support device 1 of the first embodiment, the method of manufacturing the support device 1 of the first embodiment, and the method of using the support device 1 of the first embodiment will be described in order.
- FIG. 1 is a plan view showing the support device 1 of the first embodiment observed from the + Z side.
- FIG. 2 is a side view showing the support device 1 of the first embodiment observed from the + Y side.
- 3 is a cross-sectional view taken along the line II ′ of the support device 1 shown in FIG.
- the support device 1 includes a base member 11.
- the base member 11 is made of a resin material.
- the base member 11 is comprised from the material which has translucency.
- the base member 11 is made of a material having thermoplasticity.
- An example of such a material (resin material) is an acrylic resin such as PMMA (Poly Methyl Methacrylate).
- the base member 11 is a plate-like member having a polygonal shape in plan view.
- the base member 11 includes a first surface 111, a second surface 112, a third surface 113, a fourth surface 114, a fifth surface 115, and a sixth surface 116.
- the first surface 111 is a surface parallel to the XZ plane.
- the shape of the first surface 111 is a rectangle.
- the 1st surface 111 may be called the 1st side 111 as needed.
- the second surface 112 is a surface parallel to the XZ plane.
- the second surface 112 is a surface parallel to the first surface 111.
- the second surface 112 is a surface located on the + Y side with respect to the first surface 111.
- the shape of the second surface 112 is a rectangle.
- the shape of the second surface 112 is the same as the shape of the first surface 111.
- the 2nd surface 112 may be called the 2nd side surface 112 as needed.
- the third surface 113 is a surface parallel to the YZ plane.
- the third surface 113 includes an outer edge of the first surface 111 (especially an outer edge parallel to the Z axis located on the + X side) and an outer edge of the second surface 112 (especially an outer edge located on the + X side and parallel to the Z axis). ).
- the shape of the third surface 113 is a rectangle.
- the 3rd surface 113 may be called the 3rd side surface 113 as needed.
- the fourth surface 114 is a surface parallel to the YZ plane.
- the fourth surface 114 is a surface parallel to the third surface 113.
- the fourth surface 114 is a surface located on the ⁇ X side with respect to the third surface 113.
- the fourth surface 113 includes an outer edge of the first surface 111 (particularly, an outer edge located on the ⁇ X side and parallel to the Z axis) and an outer edge of the second surface 112 (particularly located on the ⁇ X side and parallel to the Z axis). The outer edge).
- the shape of the fourth surface 114 is a rectangle.
- the shape of the fourth surface 114 is the same as the shape of the third surface 113.
- the 4th surface 114 may be called the 4th side surface 114 as needed.
- the fifth surface 115 is a surface parallel to the XY plane.
- the fifth surface 115 is a surface that connects the outer edges of the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114 (particularly, the outer edge that is located on the + Z side and is parallel to the ZY plane).
- the fifth surface 115 is a surface perpendicular to the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114.
- the shape of the fifth surface 115 is a rectangle.
- the fifth surface 115 is a surface on which lapping is performed. Note that the fifth surface 115 may be referred to as the upper surface 115 as necessary.
- the fifth surface 115 includes an upper surface 115a and a lower surface 115b.
- the upper surface 115 a is a surface located near the outer edge of the fifth surface 115.
- the upper surface 115a is a surface located on the + Z side with respect to the lower surface 115b.
- the upper surface 115a is a surface whose height (for example, the height with the sixth surface 116 as a reference position) is larger than the height of the lower surface 115b.
- the upper surface 115a is a surface on which a columnar member 12 described later is not formed.
- the lower surface 115b is a surface surrounded by the upper surface 115a on the XY plane.
- the lower surface 115b is a surface located on the ⁇ Z side with respect to the upper surface 115a.
- the lower surface 115b is a surface whose height (for example, the height with the sixth surface 116 as a reference position) is smaller than the height of the upper surface 115a.
- the lower surface 115b is a surface on which a columnar member 12 described later is formed. In the side view of the support device 1 shown in FIG. 2, for convenience of explanation, the lower surface 115b and the columnar members 12 formed on the lower surface 115b are indicated by dotted lines.
- the sixth surface 116 is a surface parallel to the XY plane.
- the sixth surface 116 is a surface parallel to the fifth surface.
- the sixth surface 116 is a surface located on the ⁇ Z side with respect to the fifth surface 115.
- the sixth surface 116 is a surface that connects the outer edges of the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114 (particularly, the outer edge located on the ⁇ Z side and parallel to the XY plane).
- the sixth surface 116 is a surface that is perpendicular to each of the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114.
- the shape of the sixth surface 116 is a rectangle.
- the sixth surface 116 is a surface on which lapping is performed. Note that the sixth surface 116 may be referred to as a lower surface 116 as necessary.
- a hole 116a is formed in the sixth surface 116 (see FIG. 3).
- the hole 116a is a hole extending from the sixth surface 116 toward the + Z side.
- the hole 116 a may not be a through hole penetrating the base member 11 from the sixth surface 116 toward the fifth surface 115.
- the hole 116a is formed mainly for the purpose of reducing the weight of the base member 11 or reducing the manufacturing cost of the base member 11.
- the base member 11 is further formed with a first through-hole portion 117a and a second through-hole portion 117b.
- Each of the first through-hole portion 117 a and the second through-hole portion 117 b is a hole that penetrates the base member 11 from the upper surface 115 a of the fifth surface 115 toward the sixth surface 116. Therefore, each of the upper surface 115a and the sixth surface 116 is formed with respective openings of the first through-hole portion 117a and the second through-hole portion 117b.
- the first through hole portion 117a and the second through hole portion 117b are formed such that a line connecting the center of the first through hole portion 117a and the center of the second through hole portion 117b is parallel to the X axis. .
- the shape of the outer edge of the first through hole 117a on the XY plane is different from the shape of the outer edge of the second through hole 117b on the XY plane.
- the shape of the outer edge of the first through hole portion 117 a is circular
- the shape of the outer edge of the second through hole portion 117 b is an ellipse whose major axis extends along the X axis. It has become.
- the first through-hole portion 117a and the second through-hole portion 117b are mainly used for positioning the support device 1 in a dispensing device DP and a measuring device MS (see FIG. 23) described later.
- a positioning pin formed on the stage of the dispensing device DP or the measuring device MS is inserted into the first through hole 117a and the second through hole 117b, so that the first through hole 117a and the second through hole are inserted.
- the portion 117b is used for alignment of the support device 1.
- the groove part 118a and 118b are further formed in the base member 11.
- the groove 118 a is formed on the first surface 111.
- the groove 118b is formed in the second surface 112.
- the grooves 118a and 118b are formed at symmetrical positions.
- Each of the groove portions 118a and 118b includes a plurality of grooves that extend along the X axis and are aligned along the Y axis (for example, grooves having a bottom portion formed in a V-shaped cross section).
- the length along the X axis of each of the groove portions 118 a and 118 b is 1 ⁇ 2 or more of the length along the X axis of at least one of the first surface 111 and the second surface 112.
- the groove portions 118a and 118b are mainly used as an area for holding the support device 1 by a transport device AM (see FIG. 23) that transports the support device 1 from a dispensing device DP described later to the measurement device MS.
- the support device 1 further includes a plurality of columnar members 12.
- Each columnar member 12 has a columnar shape extending along the Z-axis. The shape of the outer edge of each columnar member 12 on the XY plane is a circle.
- the plurality of columnar members 12 are formed on the lower surface 115 b of the base member 11.
- the plurality of columnar members 12 are formed in a matrix. In the example shown in FIGS. 1 to 3, 24 columnar members 12 are formed in a matrix of 4 rows ⁇ 6 columns.
- Each columnar member 12 is made of a resin material. Each columnar member 12 is made of a translucent material. Each columnar member 12 is made of a thermoplastic material. Each columnar member 12 is made of the same material as that of the base member 11. Each columnar member 12 is made of a material that can relatively improve the uprightness of each columnar member 12 (for example, the characteristic that the columnar member 12 along the direction intersecting the Z axis represents resistance to distortion). . As an example of such a material, acrylic resin such as PMMA described above is exemplified.
- Each columnar member 12 includes a first columnar member 121 and a second columnar member 122.
- the first columnar member 121 is formed on the lower surface 115 b of the base member 11.
- the first columnar member 121 is a columnar member extending from the lower surface 115b toward the + Z side.
- the shape of the outer edge of the first columnar member 121 on the XY plane is a circle.
- the first columnar member 121 is integrated with the base member 11.
- the first columnar member 121 is integrally formed with the base member 11. Inside the first column member 121, a hole 121l extending along the Z-axis is formed.
- the hole portion 121 l forms an opening in the sixth surface 116 of the base member 11.
- the hole 121l is formed mainly for the purpose of reducing the weight of the first pillar member 11.
- the configuration of the first columnar member 121 will be described in detail later (see FIG. 4), and detailed description thereof will be omitted here.
- the second columnar member 122 is formed on the first columnar member 121.
- the second columnar member 122 is a columnar member extending from the first columnar member 121 toward the + Z side.
- the shape of the outer edge of the second columnar member 122 on the XY plane is a circle.
- the second columnar member 122 is fixed to the first columnar member 121 by welding (for example, ultrasonic welding).
- the second columnar member 122 is a member that supports a desired support object. As an example of a desired support object, a biochip 14 used for molecular diagnosis is exemplified.
- the support device 1 further includes a plurality of cylindrical members 13.
- Each tubular member 13 is a tubular member extending along the Z axis.
- the shapes of the outer edges in the inner and outer directions of the cylindrical member 13 on the XY plane are circular. That is, the shape of the cylindrical member 13 on the XY plane is a ring shape.
- Each cylindrical member 13 is used as a set with one columnar member 12 corresponding to each cylindrical member 13. For this reason, the support device 1 includes 24 cylindrical members 13.
- Each cylindrical member 13 corresponds to each cylindrical member 13 such that at least a part of one columnar member 12 corresponding to each cylindrical member 13 is accommodated or inserted into a cavity inside each cylindrical member 13. Is fitted into one columnar member 12.
- the cylindrical member 13 currently fitted by the columnar member 12 is shown with the dotted line for convenience of explanation.
- Each cylindrical member 13 is made of a resin material. Each cylindrical member 13 is made of an elastic material. Each tubular member 13 is made of a material having higher elasticity than the material constituting each columnar member 12. Each tubular member 13 is made of a material that is more likely to be distorted or bent than the material constituting each columnar member 12. Each tubular member 13 is made of a material different from the material constituting each columnar member 12. An example of such a material is LDPE (Low Density PolyEthylene).
- FIGS. 1-3 the support apparatus 1 demonstrated using FIGS. 1-3 is an example. Therefore, a part of the configuration of the support device 1 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the support device 1 will be described.
- the base member 11 may be made of a resin other than acrylic resin.
- the base member 11 may be made of PC (Poly Carbonate).
- the base member 11 may be made of COC (Cycloolefin Copolymer).
- the base member 11 may be made of PS (Polystyrene: polystyrene).
- the base member 11 may be made of a material other than resin.
- the base member 11 may be comprised from the material which does not have translucency.
- the base member 11 may be comprised from the material which does not have thermoplasticity.
- the base member 11 may not be a plate-like member having a polygonal shape in plan view.
- At least a part of the first surface 111 may be a surface that is inclined with respect to the XZ plane (in other words, intersects, the same applies hereinafter). At least a part of the first surface 111 may be a curved surface.
- the shape of the first surface 111 may be a shape different from a rectangle (for example, an arbitrary polygon, a circle, or an ellipse).
- At least a part of the second surface 112 may be a surface that is inclined with respect to the XZ plane. At least a part of the second surface 112 may be a curved surface. At least a part of the second surface 112 may be a surface that is inclined with respect to the first surface 111.
- the shape of the second surface 112 may be a shape different from a rectangle (for example, an arbitrary polygon, a circle, or an ellipse). The shape of the second surface 112 may be different from the shape of the first surface 111.
- At least a part of the third surface 113 may be a surface that is inclined with respect to the YZ plane. At least a part of the third surface 113 may be a curved surface.
- the shape of the third surface 113 may be a shape different from a rectangle (for example, an arbitrary polygon, a circle, or an ellipse).
- At least a part of the fourth surface 113 may be a surface inclined with respect to the YZ plane. At least a part of the fourth surface 114 may be a curved surface. At least a part of the fourth surface 114 may be a surface that is inclined with respect to the third surface 113.
- the shape of the fourth surface 114 may be a shape different from a rectangle (for example, an arbitrary polygon, a circle, or an ellipse). The shape of the fourth surface 114 may be different from the shape of the third surface 113.
- At least a part of the fifth surface 115 may be a surface that is inclined with respect to the XY plane. At least a part of the fifth surface 115 may be a curved surface. At least a part of the fifth surface 115 may be a surface that is inclined at an arbitrary angle with respect to at least one of the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114. .
- the shape of the fifth surface 115 may be a shape different from a rectangle (for example, an arbitrary polygon, circle, or ellipse).
- the fifth surface 115 may be a surface that is not lapped.
- the fifth surface 115 may not include at least one of the upper surface 115a and the lower surface 115b.
- the columnar member 12 may be formed on at least a part of the fifth surface 115.
- the upper surface 115a may be a surface located at a position different from the vicinity of the outer edge of the fifth surface 115. At least a part of the upper surface 115a may be a surface on which the columnar member 12 is formed. At least a part of the lower surface 115b may be a surface that is not surrounded by the upper surface 115a on the XY plane. At least a part of the lower surface 115b may be a surface on which the columnar member 12 is not formed.
- At least a part of the sixth surface 116 may be a surface that is inclined with respect to the XY plane. At least a part of the sixth surface 116 may be a curved surface. At least a part of the sixth surface 116 may be a surface that is inclined with respect to the fifth surface 115. At least a part of the sixth surface 116 may be a surface that is inclined at an arbitrary angle with respect to at least one of the first surface 111, the second surface 112, the third surface 113, and the fourth surface 114. .
- the shape of the sixth surface 116 may be a shape different from a rectangle (for example, an arbitrary polygon, a circle, or an ellipse).
- the sixth surface 116 may be a surface that has not been lapped.
- the hole 116a may not be formed in the sixth surface 116.
- the hole 116a may not be a hole extending from the sixth surface 116 toward the + Z side.
- the hole 116a may be a hole extending from the sixth surface 116 in any direction.
- the hole 116 a may be a through hole that penetrates the base member 11 from the sixth surface 116 toward the fifth surface 115.
- the first through hole 117a and the second through hole 117b may not be formed in the base member 11. In this case, it is preferable to employ another method that does not use the first through-hole portion 117a and the second through-hole 117b for the alignment of the support device 1.
- At least one of the first through-hole portion 117a and the second through-hole 117b may be formed at any location of the base member 11. At least one of the first through hole 117a and the second through hole 117b may not be a hole that penetrates the base member 11 from the upper surface 115a of the fifth surface 115 toward the sixth surface 116. At least one of the first through-hole portion 117a and the second through-hole 117b may be a hole portion, a concave portion, or a hollow portion in which an opening is formed on the upper surface 115a (or the other surface of the base member 11).
- At least one of the first through-hole portion 117a and the second through-hole 117b may be a hole portion, a concave portion, or a hollow portion in which an opening is formed on the sixth surface 116 (or the other surface of the base member 11).
- the first through-hole portion 117a and the second through-hole portion 117b may be formed so that a line connecting the center of the first through-hole portion 117a and the center of the second through-hole portion 117b intersects the X axis.
- the shape of the outer edge of the first through hole 117a on the XY plane may be any shape (for example, any polygon or ellipse) different from a circle.
- the shape of the outer edge of the second through-hole portion 117b on the XY plane may be an arbitrary shape (for example, an arbitrary polygonal shape or a circular shape) different from an ellipse whose major axis extends along the X axis.
- the base member 11 may not have at least one of the groove portions 118a and 118b.
- the groove 118 a may be formed on the other surface of the base member 11 different from the first surface 111.
- the groove 118b may be formed on the other surface of the base member 11 different from the second surface 112.
- the grooves 118a and 118b may not be formed at symmetrical positions.
- the length along the X axis of at least one of the groove portions 118 a and 118 b may be less than 1 ⁇ 2 of the length along the X axis of at least one of the first surface 111 and the second surface 112.
- the support device 1 may include less than 24 (for example, 6) columnar members 12.
- the support device 1 may include 25 or more (for example, 96 or 384) columnar members 12.
- the support device 1 may include a single columnar member 12.
- the one or more columnar members 12 may be formed on the other surface of the base member 11 different from the lower surface 115b.
- the one or more columnar members 12 may be columnar members extending in an arbitrary direction from an arbitrary surface.
- the plurality of columnar members 12 may be formed to be distributed in an arbitrary distribution manner different from the matrix-like distribution manner.
- the shape of the outer edge of the columnar member 12 on the XY plane may be a shape (for example, an arbitrary polygon or ellipse) different from a circle.
- Each columnar member 12 may be made of a resin other than an acrylic resin such as PMMA.
- each columnar member 12 may be composed of the PC described above.
- Each columnar member 12 may be composed of the above-described COC.
- Each columnar member 12 may be composed of the above-described PS.
- Each columnar member 12 may be composed of PPE (modified PolyPhenylene Ether).
- Each columnar member 12 may be made of a material other than resin.
- Each columnar member 12 may be made of a material that does not have translucency.
- Each columnar member 12 may be made of a material that does not have thermoplasticity.
- Each columnar member 12 may be made of a material different from the material constituting the base member 11.
- the columnar member 12 may not include at least one of the first columnar member 121 and the second columnar member 122.
- the first columnar member 121 and the second columnar member 122 may be integrated.
- the first columnar member 121 and the second columnar member 122 may be integrally formed.
- the first columnar member 121 may be formed on the other surface of the base member 11 different from the lower surface 115b.
- the first columnar member 121 may be a columnar member extending in an arbitrary direction from an arbitrary surface.
- the shape of the outer edge of the first columnar member 121 on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the first columnar member 121 may not be integrated with the base member 11.
- the first columnar member 121 may be molded separately from the base member 11. Inside the first pillar member 121, the hole 121l may not be formed. Inside the first column member 121, a hole 121l extending along a direction different from the direction along the Z-axis may be formed. The hole 121l may not form an opening.
- the hole 121l may form an opening on the other surface of the base member 11 different from the sixth surface 116.
- the second columnar member 122 may be a columnar member extending from the first columnar member 121 in an arbitrary direction.
- the shape of the outer edge of the second columnar member 122 on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the second columnar member 122 may be fixed to the first columnar member 121 by a method different from welding (for example, ultrasonic welding).
- the support device 1 may include less than 24 (for example, 6) cylindrical members 13.
- the support device 1 may include 25 or more (for example, 96 or 384) cylindrical members 13.
- the support device 1 may include a single cylindrical member 13.
- the one or more cylindrical members 13 may be cylindrical members extending in an arbitrary direction.
- the shape of the outer edge of at least one of the inner side direction and the outer side direction of the cylindrical member 13 on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or an ellipse).
- Each cylindrical member 13 may be made of a resin other than LDPE.
- each cylindrical member 13 may be made of PTFE (PolyTetraFluoroethylene: polytetrafluoroethylene: tetrafluoroethylene resin).
- Each tubular member 13 may be made of a material that does not have elasticity.
- Each tubular member 13 may not be made of a material having higher elasticity than the material constituting each columnar member 12.
- Each tubular member 13 may not be made of a material that is more likely to be distorted or bent than the material constituting each columnar member 12.
- Each tubular member 13 may be made of the same material as that constituting each columnar member 12.
- FIG. 4A is a plan view of the first columnar member 121 observed from the + Z side.
- FIG. 4B is a cross-sectional view taken along the line IV-IV ′ of the first columnar member 121 shown in FIG.
- FIG. 4C is a side view of the first columnar member 121 observed from the + Y side.
- FIG. 4D is an enlarged sectional view of the vicinity of the welding member 121b in the IV-IV ′ sectional view of the first columnar member 121 shown in FIG.
- the first columnar member 121 includes a first upper surface 121a, a welding member 121b, a first outer surface 121c, a second upper surface 121d, and a second outer surface 121e.
- the first upper surface 121a is a surface parallel to the XY plane.
- the first upper surface 121 a is a surface located on the most + Z side among the surfaces constituting the first columnar member 121.
- the first upper surface 121a is a surface facing the + Z side.
- the shape of the outer edge of the first upper surface 121a on the XY plane is a square.
- the welding member 121b is formed on the first upper surface 121a.
- the welding member 121b is a member integrated with the first upper surface 121a.
- the welding members 121b are distributed in a distribution manner that forms a ring shape on the first upper surface 121a.
- the shape of the outer edge of the welding member 121b on the XZ plane is a triangle (see FIG. 4D).
- the center of the welding member 121b distributed in the ring-shaped distribution mode that is, the center of the ring shape on the XY plane
- the welding member 121b is melted by being irradiated with ultrasonic waves when the first columnar member 121 and the second columnar member 122 are fixed. As a result, the first columnar member 121 and the second columnar member 122 are fixed by the welding member 121b acting as an adhesive.
- the first outer surface 121c is a surface extending from the outer edge of the first upper surface 121a toward the -Z side.
- the first outer surface 121c faces away from the center line of the first columnar member 121 parallel to the Z-axis (specifically, the line passing through the center of the first upper surface 121a on the XY plane and parallel to the Z-axis). ing.
- a direction away from the center line of the first columnar member 121 parallel to the Z axis is referred to as an “outward direction” and approaches the center line of the first columnar member 121 parallel to the Z axis.
- the direction is referred to as “inward direction”.
- the first outer surface 121c is a surface that is inclined with respect to the Z-axis.
- the first outer surface 121c is inclined with respect to the Z axis so that the diameter of the first outer surface 121c on the XY plane increases toward the ⁇ Z side.
- the first outer surface 121c is inclined with respect to the Z axis so as to expand outward as it goes toward the -Z side.
- the shape of the first outer surface 121c is a tapered shape.
- the shape of the outer edge of the first outer surface 121c on the XY plane is a square.
- the center of the first outer surface 121c on the XY plane (that is, the center of the square) coincides with the center of the first upper surface 121a on the XY plane.
- the second upper surface 121d is a surface extending outward from the -Z side outer edge of the first outer surface 121c.
- the second upper surface 121d is a surface facing the + Z side.
- the second upper surface 121d is a surface parallel to the XY plane.
- the shape of the outer edge in the inner direction of the second upper surface 121d on the XY plane is a square.
- the shape of each outer edge of the second upper surface 121d in the outer direction on the XY plane is a circle.
- the center of the second upper surface 121d on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 121a on the XY plane.
- the second outer surface 121e is a surface extending from the outer edge of the second upper surface 121c in the outward direction toward the ⁇ Z side.
- the second outer surface 121e is a surface facing the outer direction.
- the second outer surface 121e is a surface parallel to the Z axis.
- the shape of the outer edge of the second outer surface 121e on the XY plane is a circle.
- the center of the second outer surface 121e on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 121a on the XY plane.
- the third outer surface 121f is a surface extending from the ⁇ Z side outer edge of the second outer surface 121e toward the ⁇ Z side.
- the third outer surface 121f is a surface facing the outer direction.
- the third outer surface 121f is a surface that is inclined with respect to the Z-axis.
- the third outer surface 121f is inclined with respect to the Z axis so that the diameter of the third outer surface 121f on the XY plane increases toward the ⁇ Z side.
- the third outer surface 121f is inclined with respect to the Z axis so as to expand outward as it goes toward the ⁇ Z side.
- the shape of the third outer surface 121f is a tapered shape.
- the diameter of the third outer surface 121f on the XY plane is equal to or larger than the diameter of the second outer surface 121e on the XY plane.
- the shape of the outer edge of the third outer surface 121f on the XY plane is a circle.
- the center of the third outer surface 121f on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 121a on the XY plane.
- the fourth outer surface 121g is a surface extending from the ⁇ Z side outer edge of the third outer surface 121f toward the ⁇ Z side.
- the fourth outer surface 121g is a surface extending from the fifth surface 115 (particularly, the lower surface 115b) of the base member 11 toward the + Z side.
- the fourth outer surface 121g is a surface facing the outer direction.
- the fourth outer surface 121g is a surface parallel to the Z axis.
- the shape of the outer edge of the fourth outer surface 121g on the XY plane is a circle.
- the center of the fourth outer surface 121g on the XY plane that is, the center of the circle) coincides with the center of the first upper surface 121a on the XY plane.
- the first lower surface 121h is a surface parallel to the XY plane.
- the first lower surface 121h is a surface facing the ⁇ Z side.
- the first lower surface 121h is a surface located closer to the ⁇ Z side than the first upper surface 121a.
- the shape of the outer edge of the first lower surface 121h on the XY plane is a circle.
- the center of the first lower surface 121h on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 121a on the XY plane.
- the first inner surface 121i is a surface extending from the outer edge of the first lower surface 121h toward the -Z side.
- the first inner surface 121i is a surface facing the inner direction.
- the first inner surface 121i is a surface that is inclined with respect to the Z-axis.
- the first inner surface 121i is inclined with respect to the Z axis so that the diameter of the first inner surface 121i on the XY plane increases toward the ⁇ Z side.
- the first inner surface 121i is inclined with respect to the Z axis so as to expand outward as it goes toward the -Z side.
- the shape of the first inner surface 121i is a tapered shape.
- the shape of the outer edge of the first inner surface 121i on the XY plane is a circle.
- the center of the first inner surface 121i on the XY plane that is, the center of the circle) coincides with the center of the first lower surface 121h on the XY plane.
- the second lower surface 121j is a surface extending outward from the outer edge on the ⁇ Z side of the first inner surface 121i.
- the second lower surface 121j is a surface facing the ⁇ Z side.
- the second lower surface 121j is a surface parallel to the XY plane.
- the shape of the outer edge in the inner direction and the outer direction of the second lower surface 121j on the XY plane is a circle.
- the center of the second lower surface 121j on the XY plane (that is, the center of the circle) coincides with the center of the first lower surface 121h on the XY plane.
- the second inner surface 121k is a surface extending from the outer edge of the second lower surface 121j toward the ⁇ Z side.
- the second inner surface 121k is a surface extending from the sixth surface 116 of the base member 11 toward the + Z side.
- the second inner surface 121k is a surface facing the inner direction.
- the second inner surface 121k is a surface that is inclined with respect to the Z-axis.
- the second inner surface 121k is inclined with respect to the Z axis so that the diameter of the second inner surface 121k on the XY plane increases toward the ⁇ Z side.
- the second inner surface 121k is inclined with respect to the Z axis so as to expand outward as it goes toward the ⁇ Z side.
- the shape of the second outer surface 121k is a tapered shape.
- the shape of the outer edge of the second inner surface 121k on the XY plane is a circle.
- the center of the second inner surface 121k on the XY plane (that is, the center of the circle) coincides with the center of the first lower surface 121h on the XY plane.
- the first columnar member 121 has a hole 121l surrounded by the first lower surface 121h, the first inner surface 121i, the second lower surface 121j, and the second inner surface 121k.
- the 1st columnar member 121 demonstrated using FIG. 4 (a) to FIG.4 (d) is an example. Therefore, a part of the configuration of the first columnar member 121 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the first columnar member 121 will be described.
- the first columnar member 121 includes a first upper surface 121a, a welding member 121b, a first outer surface 121c, a second upper surface 121d, a second outer surface 121e, a third outer surface 121f, a fourth outer surface 121g, a first lower surface 121h, and a first inner surface 121i.
- At least one of the second lower surface 121j and the second inner surface 121k may not be provided.
- At least a part of the first upper surface 121a may be a surface inclined with respect to the XY plane. At least a part of the first upper surface 121a may be a curved surface. The first upper surface 121 a may not be a surface located on the most + Z side among the surfaces constituting the first columnar member 121.
- the shape of the outer edge of the first upper surface 121a on the XY plane may be a shape different from a square (for example, an arbitrary polygon, circle, or ellipse).
- the welding member 121b may be a member that is not integrated with the first upper surface 121a.
- the welding member 121b may be a member formed separately from the first upper surface 121a.
- the welding member 121b may be distributed on the first upper surface 121a in a distribution manner different from the ring shape.
- the shape of the welding member 121b on the XZ plane may be a shape different from a triangle (for example, an arbitrary polygon, a circle, or an ellipse).
- the center of the welding member 121b may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the first outer surface 121c may be a surface parallel to the Z axis. At least a part of the first outer surface 121c may be a curved surface. At least a part of the first outer surface 121c may not be tapered.
- the shape of the first outer surface 121c on the XY plane may be a shape different from a square (for example, an arbitrary polygon, a circle, or an ellipse).
- the center of the first outer surface 121c on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the second upper surface 121d may be a surface that is inclined with respect to the XY plane. At least a part of the second upper surface 121d may be a curved surface.
- the shape of the outer edge in the inner direction of the second upper surface 121d on the XY plane may be a shape different from a square (for example, an arbitrary polygon, circle, or ellipse).
- the shape of the outer edge of the second upper surface 121d in the outer direction on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or an ellipse).
- the center of the second upper surface 121d on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the second outer surface 121e may be a surface inclined with respect to the Z axis. At least a part of the second outer surface 121e may be a curved surface.
- the shape of the outer edge of the second outer surface 121e on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the center of the second outer surface 121e on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the third outer surface 121f may be a surface parallel to the Z axis. At least a part of the third outer surface 121f may be a curved surface. The shape of at least a part of the third outer surface 121f may not be a tapered shape. The diameter of at least a part of the third outer surface 121f on the XY plane may be smaller than the diameter of at least a part of the second outer surface 121e on the XY plane. The shape of the outer edge of the third outer surface 121f on the XY plane may be a shape different from a circle (for example, an arbitrary polygon). The center of the third outer surface 121f on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the fourth outer surface 121g may be a surface inclined with respect to the Z axis. At least a part of the fourth outer surface 121g may be a curved surface.
- the shape of the outer edge of the fourth outer surface 121g on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the center of the fourth outer surface 121g on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the first lower surface 121h may be a surface inclined with respect to the XY plane. At least a part of the first lower surface 121h may be a curved surface.
- the shape of the outer edge of the first lower surface 121h on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or an ellipse).
- the center of the first lower surface 121h on the XY plane may not coincide with the center of the first upper surface 121a on the XY plane.
- At least a part of the first inner surface 121i may be a surface parallel to the Z axis. At least a part of the first inner surface 121i may be a curved surface. The shape of at least a part of the first inner surface 121i may not be a tapered shape. The shape of the outer edge of the first inner surface 121i on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse). The center of the first inner surface 121i on the XY plane may not coincide with the center of the first lower surface 121h on the XY plane.
- At least a part of the second lower surface 121j may be a surface that is inclined with respect to the XY plane. At least a part of the second lower surface 121j may be a curved surface.
- the inner diameter of the second lower surface 121j on the XY plane may be less than the diameter of at least a part of the first inner surface 121i on the XY plane.
- the outer diameter of the second lower surface 121j on the XY plane may be equal to or smaller than the diameter of at least a part of the first inner surface 121i on the XY plane.
- the shape of the outer edge in the inner direction and the outer direction of the second lower surface 121j on the XY plane may be a shape (for example, an arbitrary polygon) different from the circle.
- the center of the second lower surface 121j on the XY plane may not coincide with the center of the first lower surface 121h on the XY plane.
- At least a part of the second inner surface 121k may be a surface parallel to the Z axis. At least a part of the second inner surface 121k may be a curved surface. The shape of at least a part of the second outer surface 121k may not be a tapered shape. The shape of the outer edge of the second inner surface 121k on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse). The center of the second inner surface 121k on the XY plane may not coincide with the center of the first lower surface 121h on the XY plane.
- FIG. 5A is a plan view of the second columnar member 122 observed from the + Z side.
- FIG. 5B is a VV ′ cross-sectional view of the second columnar member 122 shown in FIG.
- FIG. 5C is a side view of the second columnar member 122 observed from the + Y side.
- FIG. 5D is a plan view of the first columnar member 121 observed from the ⁇ Z side.
- the second columnar member 122 includes a first upper surface 122a, a second upper surface 122b, a first outer surface 122c, four holes 122d, A lower surface 122e, a first inner surface 122f, and a second lower surface 122g are provided.
- the first upper surface 122 a is a surface located on the most + Z side among the surfaces constituting the second columnar member 122.
- the first upper surface 122a is a surface facing the + Z side.
- the first upper surface 122a is a surface parallel to the XY plane.
- the shape of the outer edge of the first upper surface 122a on the XY plane is a square.
- the second upper surface 122b is a surface disposed around the first upper surface 122a.
- the second upper surface 122b is a surface that is inclined with respect to the XY plane.
- the second upper surface 122b is a surface that is inclined with respect to the first upper surface 122a.
- the second upper surface 122b faces away from the center line of the second columnar member 122 parallel to the Z axis (that is, a line passing through the center of the first upper surface 122a on the XY plane and parallel to the Z axis).
- a direction away from the center line of the second columnar member 122 parallel to the Z axis is referred to as an “outward direction” and approaches the center line of the second columnar member 122 parallel to the Z axis.
- the direction is referred to as “inward direction”.
- the second upper surface 122b is a surface facing the + Z side and facing the outer side.
- the shape of the outer edge in the inner direction of the second upper surface 122b on the XY plane is a square.
- the shape of the outer edge of the second upper surface 122b in the outer direction on the XY plane is a circle.
- the first outer surface 122c is a surface extending from the outer edge of the second upper surface 122b in the outward direction toward the ⁇ Z side.
- the first outer surface 122c is a surface facing the outer direction.
- the first outer surface 122c is a surface parallel to the Z axis.
- the shape of the outer edge of the first outer surface 122c on the XY plane is a circle.
- the center of the first outer surface 122c on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 122a on the XY plane.
- Each of the four hole portions 122d is a hole formed in the first outer surface 122c.
- the four holes 122d are formed so as to be located on the same XY plane.
- the four holes 122d are formed so as to be arranged at equal intervals on a circumference corresponding to the outer edge of the first outer surface 122c on the XY plane.
- Each of the four hole portions 122d is a hole that is recessed inward from the first outer surface 122c.
- Each of the four hole portions 122d does not penetrate the second columnar member 122.
- the four holes 122d can be fitted with four protrusions 13e included in the tubular member 13 described later.
- the first lower surface 122e is a surface extending inward from the outer edge on the ⁇ Z side of the first outer surface 122c.
- the first lower surface 122e is a surface facing the ⁇ Z side.
- the first lower surface 122e is a surface parallel to the XY plane.
- the shape of the outer edge in the outer direction of the first lower surface 122e on the XY plane is a circle.
- the shape of the outer edge in the inner direction of the first lower surface 122e on the XY plane is a square.
- the center of the first lower surface 122e on the XY plane (that is, the center of a circle or a square) coincides with the center of the first upper surface 122a on the XY plane.
- the first inner surface 122f is a surface extending from the inner edge of the first lower surface 122e toward the + Z side.
- the first inner surface 122f is a surface facing the inner direction.
- the first inner surface 122f is a surface that is inclined with respect to the Z-axis.
- the first inner surface 122f is inclined with respect to the Z axis so that the diameter of the first inner surface 122f on the XY plane increases toward the ⁇ Z side.
- the first inner surface 122f is inclined with respect to the Z axis so as to expand outward as it goes toward the ⁇ Z side.
- the shape of the first inner surface 122f is a tapered shape.
- the shape of the outer edge of the first inner surface 122f on the XY plane is a square.
- the center of the first inner surface 122f on the XY plane coincides with the center of the first upper surface 122a on the XY plane.
- the second lower surface 122g is a surface extending inward from the outer edge on the + Z side of the first inner surface 122f.
- the second lower surface 122g is a surface facing the ⁇ Z side.
- the second lower surface 122g is a surface parallel to the XY plane.
- the shape of the outer edge of the second lower surface 122g on the XY plane is a square.
- the center of the second lower surface 122g on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 122a on the XY plane.
- the second columnar member 122 described with reference to FIGS. 5A to 5B is an example. Therefore, a part of the configuration of the second columnar member 122 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the second columnar member 122 will be described.
- the second columnar member 122 includes at least one of a first upper surface 122a, a second upper surface 122b, a first outer surface 122c, four holes 122d, a first lower surface 122e, a first inner surface 122f, and a second lower surface 122g. It does not have to be.
- At least a part of the first upper surface 122a may be a surface inclined with respect to the XY plane. At least a part of the first upper surface 122a may be a curved surface.
- the first upper surface 122 a may not be a surface located on the most + Z side among the surfaces constituting the second columnar member 122.
- the first upper surface 122a may be a surface facing a direction different from the + Z side.
- the shape of the outer edge of the first upper surface 122a on the XY plane may be a shape different from a square (for example, an arbitrary polygon, a circle, or an ellipse).
- At least a part of the second upper surface 122b may be a surface parallel to the XY plane. At least a part of the second upper surface 122b may be a surface parallel to the first upper surface 122a.
- the second upper surface 122b may be a surface facing a direction different from the outer direction.
- the shape of the outer edge in the inner direction of the second upper surface 122b on the XY plane may be a shape different from a square (for example, an arbitrary polygon, circle, or ellipse).
- the shape of the outer edge of the second upper surface 122b in the outer direction on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or an ellipse).
- At least a part of the first outer surface 122c may be a surface inclined with respect to the Z axis. At least a part of the first outer surface 122c may be a curved surface.
- the shape of the outer edge of the first outer surface 122c on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the center of the first outer surface 122c on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least one of the four hole portions 122d may be formed to be located on another XY plane different from the XY plane where the other hole portions 122d are located.
- the four holes 122d may be formed so as to be different or arranged at an arbitrary interval on a circumference corresponding to the outer edge of the first outer surface 122c on the XY plane. At least one of the four hole portions 122d may penetrate the second columnar member 122.
- the second columnar member 122 may include three or less or five or more holes 122d.
- the second columnar member 122 may include four or any number of protrusions in addition to or instead of the four holes 122d.
- the cylindrical member 13 to be described later includes four or any number of holes that can be fitted to the protrusions included in the second columnar member 122 in addition to or instead of the four protrusions 13e. Also good.
- At least a part of the first lower surface 122e may be a surface that is inclined with respect to the XY plane.
- the outer diameter of the first lower surface 122e on the XY plane may be different from the diameter of at least a part of the first outer surface 122c on the XY plane.
- the inner diameter of the first lower surface 122e on the XY plane may be greater than or equal to the diameter of at least a part of the first outer surface 122c on the XY plane.
- the shape of the outer edge in the outer direction of the first lower surface 122e on the XY plane may be a shape different from a circle (for example, an arbitrary polygon).
- the shape of the outer edge in the inner direction of the first lower surface 122e on the XY plane may be a shape different from a square (for example, an arbitrary circle or polygon).
- the center of the first lower surface 122e on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least a part of the first inner surface 122f may be a surface parallel to the Z axis. At least a part of the first inner surface 122f may be a curved surface. The shape of at least a part of the first inner surface 122f may not be a tapered shape. The shape of the outer edge of the first inner surface 122f on the XY plane may be a shape different from a square (for example, an arbitrary polygon, circle, or ellipse). The center of the first inner surface 122f on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least a part of the second lower surface 122g may be a surface that is inclined with respect to the XY plane. At least a part of the second lower surface 122g may be a curved surface.
- the shape of the second lower surface 122g on the XY plane may be a shape different from a square (for example, an arbitrary polygon, a circle, or an ellipse).
- the center of the second lower surface 122g on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- FIG. 6A is a plan view of the cylindrical member 13 observed from the + Z side.
- FIG. 6B is a cross-sectional view taken along the line VI-VI ′ of the cylindrical member 13 shown in FIG.
- FIG. 6C is a side view of the cylindrical member 122 observed from the + Y side.
- FIG. 6D is an enlarged cross-sectional view of the vicinity of the first inner surface 13b in the VI-VI ′ cross-sectional view of the cylindrical member 13 shown in FIG.
- the tubular member 13 includes a first upper surface 13a, a first inner surface 13b, a first outer surface 13c, a first lower surface 13d, and four protrusions. 13e.
- the first upper surface 13 a is a surface located on the most + Z side among the surfaces constituting the cylindrical member 13.
- the first upper surface 13a is a surface facing the + Z side.
- the first upper surface 13a is a surface parallel to the XY plane.
- the shape of the outer edge in the inner direction and the outer direction of the first upper surface 13a on the XY plane is a circle.
- a direction away from the center line of the cylindrical member 13 parallel to the Z axis that is, a line passing through the center of the first upper surface 13a on the XY plane and parallel to the Z axis
- the direction is referred to as “direction” and the direction approaching the center line of the cylindrical member 13 parallel to the Z axis is referred to as “inward direction”.
- the first inner surface 13b is a surface extending from the outer edge in the inner direction of the first upper surface 13a toward the -Z side.
- the first inner surface 13b is a surface facing the inner direction.
- the shape of the first inner surface 13b on the XY plane is a circle.
- the first inner surface 13b includes a first inner surface portion 13b-1 and a second inner surface portion 13b-2.
- the first inner surface portion 13b-1 is a surface extending from the outer edge of the first upper surface 13a toward the -Z side.
- the first inner surface portion 13b-1 is a surface inclined with respect to the Z axis.
- the first inner surface portion 13b-1 is inclined with respect to the Z axis so that the diameter of the first inner surface portion 13b-1 on the XY plane decreases toward the ⁇ Z side.
- the first inner surface portion 13b-1 is inclined with respect to the Z axis so as to shrink toward the inner side as it goes toward the -Z side.
- the shape of the first inner surface portion 13b-1 is a tapered shape.
- the second inner surface portion 13b-2 is a surface extending from the -Z side outer edge of the first inner surface portion 13b-1 toward the -Z side.
- the second inner surface portion 13b-2 is a surface parallel to the Z axis.
- the first outer surface 13c is a surface extending from the outer edge of the first upper surface 13a toward the -Z side.
- the first outer surface 13c is a surface facing the outer side direction.
- the first outer surface 13c is a surface parallel to the Z axis.
- the shape of the outer edge of the first outer surface 13c on the XY plane is a circle.
- the first lower surface 13 d is a surface located on the most ⁇ Z side among the surfaces constituting the cylindrical member 13.
- the first lower surface 13d is a surface extending outward from the ⁇ Z side outer edge of the first inner surface 13b.
- the first lower surface 13d is a surface extending inward from the outer edge on the outer edge-Z side of the first outer surface 13c.
- the first lower surface 13d is a surface facing the ⁇ Z side.
- the first lower surface 13d is a surface parallel to the XY plane.
- the shape of the outer edge in the outer direction and the inner direction of the first lower surface 13d on the XY plane is a circle.
- Each of the four protrusions 13e is a protrusion formed on the first inner surface 13b.
- Each of the four protrusions 13e is a protrusion formed on the second inner surface portion 13b-2.
- Each of the four protrusions 13e is a protrusion protruding inward from the first inner surface 13b.
- the four protrusions 13e are formed so as to be positioned on the same XY plane.
- the four protrusions 13e are formed so as to be arranged at equal intervals on a circumference corresponding to the outer edge of the first inner surface 13b on the XY plane.
- Each of the four protrusions 13e can be fitted into each of four holes 122d provided in the second columnar member 122.
- FIG. 6 (a) to FIG.6 (d) is an example. Therefore, a part of the configuration of the cylindrical member 13 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the cylindrical member 13 will be described.
- the cylindrical member 13 may not include at least one of the first upper surface 13a, the first inner surface 13b, the first outer surface 13c, the first lower surface 13d, and the four protruding portions 13e.
- the first upper surface 13 a may not be a surface located on the most + Z side among the surfaces constituting the cylindrical member 13.
- the first upper surface 13a may be a surface facing a direction different from the + Z side.
- At least a part of the first upper surface 13a may be a surface inclined with respect to the XY plane.
- At least a part of the first upper surface 13a may be a curved surface.
- the shape of the outer edge of at least one of the inner and outer directions of the first upper surface 13a on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the shape of the outer edge of the first inner surface 13b on the XY plane may be a shape different from a circle (for example, an arbitrary polygon).
- the first inner surface 13b may not include at least one of the first inner surface portion 13b-1 and the second inner surface portion 13b-2.
- At least a part of the first inner surface portion 13b-1 may be a surface parallel to the Z axis.
- At least a part of the first inner surface portion 13b-1 may be a curved surface.
- the shape of at least a part of the first inner surface portion 13b-1 may not be a tapered shape.
- At least a part of the second inner surface portion 13b-2 may be a surface inclined with respect to the Z axis.
- At least a part of the second inner surface portion 13b-2 may be a curved surface.
- At least a part of the first outer surface 13c may be a surface inclined with respect to the Z axis. At least a part of the first outer surface 13c may be a curved surface.
- the shape of the outer edge of the first outer surface 13c on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the first lower surface 13d may not be a surface located on the most ⁇ Z side among the surfaces constituting the cylindrical member 13. At least a part of the first lower surface 13d may be a surface that is inclined with respect to the XY plane. At least a part of the first lower surface 13d may be a curved surface.
- the shape of the outer edge of at least one of the inner and outer directions of the first lower surface 13d on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- At least one of the four protrusions 13e may be a protrusion formed on the first inner surface portion 13b-1. At least one of the four protrusions 13e may be formed so as to be located on another XY plane different from the XY plane where the other protrusions 13e are located. The four protrusions 13e may be formed so as to be different or arranged at arbitrary intervals on a circumference corresponding to the outer edge of the first inner surface 13b on the XY plane.
- the cylindrical member 13 may include three or less or five or more protrusions 13e.
- FIG. 7 shows the first columnar member 121 and the second columnar member 121 in a state where the four protrusions 13e and the four holes 122d are fitted (hereinafter, this state is referred to as “initial state” as appropriate).
- 4 is a cross-sectional view showing a cross section of a columnar member 122 and a cylindrical member 13 along an XZ plane.
- the first outer surface 122 c of the second columnar member 122 is located outward from the second outer surface 121 e of the first columnar member 121.
- the diameter of the first outer surface 122c on the XY plane is larger than the diameter of the second outer surface 121e on the XY plane.
- the distance between the first outer surface 122c and the second outer surface 121e on the XY plane is the size of each protrusion 13e on the XY plane (that is, the distance from the second inner surface portion 13b-2 to the top of the protrusion 13e). Bigger than).
- the first lower surface 122e of the second columnar member 122 is located on the + Z side with respect to the second upper surface 121d of the first columnar member 121.
- the first lower surface 122e and the second upper surface 121d are not in contact with each other.
- the first inner surface 122f of the second columnar member 122 can be fitted to at least a part of the first outer surface 121c of the first columnar member 121 (or when the first columnar member 121 and the second columnar member 122 are fixed) (or , Contactable or opposable surface).
- the inclination angle of the first inner surface 122f with respect to the Z axis is the same as the inclination angle of the first outer surface 121c with respect to the Z axis.
- the shape of the outer edge of the first inner surface 122f on the XY plane is the same as the shape of the outer edge of the first outer surface 121c on the XY plane.
- the diameter of the first inner surface 122f on the XY plane is the same as the diameter of the first outer surface 121c on the XY plane ( However, an error due to a margin that can be fitted or fitting accuracy may be considered).
- the second lower surface 122g of the second columnar member 122 can be fitted (or contactable) with the first upper surface 121a of the first columnar member 121 when the first columnar member 121 and the second columnar member 122 are fixed. It is a surface that can be opposed).
- the shape of the outer edge of the second lower surface 122g on the XY plane is the same as the shape of the outer edge of the first upper surface 121a on the XY plane.
- the diameter of the second lower surface 122g on the XY plane is the same as the diameter of the first upper surface 121a on the XY plane (however, an error caused by a margin capable of fitting or fitting accuracy may be considered). is there.
- the first inner surface 13b of the cylindrical member 13 is a surface that can be fitted (or can be contacted or opposed) with the first outer surface 122c of the second columnar member 122 when the cylindrical member 13 is fitted into the columnar member 12. is there. That is, when the tubular member 13 is fitted into the columnar member 12, the inside of the cylinder defined by the first inner surface 13b while at least a part of the first inner surface 13b is fitted to at least a part of the first outer surface 122c.
- the second columnar member 122 is fitted into the second.
- the first inner surface 13b extends over the entire circumferential direction of the first inner surface 13b and the first outer surface 122c (that is, the direction along the Z axis). At least one fitting surface is secured to which the first outer surface 122c is fitted.
- the cylindrical member 13 is made of an elastic material.
- the first inner surface 13b is connected to the first columnar member 122 from the second columnar member 122.
- a stress acting in the outward direction is applied.
- the 1st inner surface 13b is a surface which can be extended so that the diameter may be expanded with the stress added from such a 2nd columnar member 122, and the elasticity which the cylindrical member 13 has.
- the first inner surface 13b and the first outer surface 122c are relatively closely adhered to each other as compared with the case where the first inner surface 13b is a surface that cannot extend so as to increase its diameter.
- the cylindrical member 13 is attached to the columnar member 12.
- the diameter of the inner surface 13c on the XY plane is equal to or smaller than the diameter of the first outer surface 122c on the XY plane.
- the shape of the outer edge of the first inner surface 122f on the XY plane is the same as or similar to the shape of the outer edge of the first outer surface 121c on the XY plane.
- the first inner surface portion 13b-1 of the cylindrical member 13 does not face (or contact) the first outer surface 122c of the second columnar member 122.
- the second inner surface portion 13b-2 of the cylindrical member 13 is fitted (or contacted or opposed) to at least a part of the first outer surface 122c.
- the boundary line between the first inner surface portion 13b-1 and the second inner surface portion 13b-2 coincides with the boundary line between the second upper surface 122b and the first outer surface 122c.
- the distance D from the first upper surface 122a of the second columnar member 122 to the first upper surface 13a of the cylindrical member 13 (however, the direction from the first upper surface 122a toward the + Z side is defined as a positive direction) is The predetermined distance D1 or more.
- the predetermined distance D1 is a distance at which a space SP1 surrounded by the first upper surface 122a and the second upper surface 122b of the second columnar member 122 and the first inner surface portion 13b-1 of the tubular member 13 can be secured.
- the predetermined distance D1 sets the volume (volume) of the space SP1 surrounded by the first upper surface 122a and the second upper surface 122b of the second columnar member 122 and the first inner surface portion 13b-1 of the cylindrical member 13 to be a predetermined amount or more.
- the initial state described with reference to FIG. 7 is an example. Therefore, a state different from the initial state shown in FIG. 7 may be adopted as the initial state. Hereinafter, an example of modification of the initial state will be described.
- At least a part of the first outer surface 122c of the second columnar member 122 may be located inward of at least a part of the second outer surface 121e of the first columnar member 121. At least a part of the first outer surface 122c and at least a part of the second outer surface 121e may be aligned along the Z axis.
- the diameter of at least a part of the first outer surface 122c on the XY plane may be equal to or smaller than the diameter of at least a part of the second outer surface 121e on the XY plane.
- the distance between at least a part of the first outer surface 122c along the X axis and at least a part of the second outer surface 121e may be equal to or smaller than the size of each protrusion 13e along the X axis.
- At least part of the first lower surface 122e of the second columnar member 122 may be in contact with at least part of the second upper surface 121d of the first columnar member 121.
- At least a part of the first inner surface 122f of the second columnar member 122 may not be fitted (or contacted or opposed) with at least a part of the first outer surface 121c of the first columnar member 121.
- the inclination angle of at least part of the first inner surface 122f with respect to the Z axis may be different from the inclination angle of at least part of the first outer surface 121c with respect to the Z axis.
- the shape of at least part of the outer edge of the first inner surface 122f on the XY plane may be different from the shape of at least part of the outer edge of the first outer surface 121c on the XY plane.
- At least a part of the second lower surface 122g of the second columnar member 122 may not be fitted (or contacted or opposed) with at least a part of the first upper surface 121a of the first columnar member 121.
- the shape of at least part of the outer edge of the second lower surface 122g on the XY plane may be different from the shape of at least part of the outer edge of the first upper surface 121a on the XY plane.
- the first inner surface 13b may be a surface that cannot extend so as to increase its diameter. Regardless of the presence or absence of stress applied from the second columnar member 122, the cylindrical member 13 may have such rigidity that the diameter of the first inner surface 13b is maintained.
- the diameter of at least a part of the inner surface 13c on the XY plane may be equal to or larger than the diameter of at least a part of the first outer surface 122c on the XY plane.
- the shape of at least a portion of the outer edge of the first inner surface 122f on the XY plane may not be the same as or similar to the shape of the outer edge of at least a portion of the first outer surface 121c on the XY plane.
- At least a part of the first inner surface portion 13b-1 of the cylindrical member 13 may be fitted (or contacted or opposed) to at least a part of the outer surface 122c of the second columnar member 122.
- at least a part of the second inner surface portion 13b-2 of the cylindrical member 13 may not be fitted (or contacted or opposed) to the outer surface 122c.
- at least a part of the boundary line between the first inner surface portion 13b-1 and the second inner surface portion 13b-2 coincides with the boundary line between the second upper surface 122b and the first outer surface 122c. It does not have to be.
- FIGS. 8A to 8D are cross-sectional views showing a cross section along the XZ plane of the support device 1 when each step of manufacturing the support device 1 of the first embodiment is performed. is there.
- the base member 11 integrated with the 24 first columnar members 121, the 24 second columnar members 122, and the 24 tubular members 13 are separately provided. Manufactured.
- Each of the base member 11, each 2nd columnar member 122, and each cylindrical member 13 is manufactured by the injection molding method, for example.
- each of the base member 11, each 2nd columnar member 122, and each cylindrical member 13 may be manufactured by the arbitrary manufacturing methods different from the injection molding method, for example.
- the first columnar member 121 and the second columnar member 122 are separately manufactured.
- the second outer surface 121e having a relatively small diameter is sandwiched between the third outer surface 121f, the fourth outer surface 121g, and the first outer surface 122c having a relatively large diameter along the Z axis. Yes.
- the columnar member 12 in which the first columnar member 121 and the second columnar member 122 are integrated is manufactured, the columnar member 12 may be removed from the mold depending on the structure of the mold. It can be difficult.
- the second outer surface 121e having a relatively small diameter is sandwiched between two surfaces having a relatively large diameter along the Z axis. It will not be. Therefore, the possibility that it is difficult to remove the first columnar member 121 and the second columnar member 122 from the mold is relatively reduced. That is, the columnar member 12 can be manufactured relatively easily.
- the base member 11 integrated with the 24 first columnar members 121, the 24 second columnar members 122, and the 24 cylindrical members 13 are combined, whereby the support device 1 is Manufactured.
- 8A to 8D for simplification of the drawing, one first columnar member 121, one second columnar member 122, and one cylindrical member 13 are included. Focus on the combination and proceed with the explanation.
- the second columnar member 122 is stacked on the first columnar member 121.
- the second columnar member 122 is fitted to the first columnar member 121 such that the first upper surface 121a of the first columnar member 121 and the second lower surface 122g of the second columnar member 122 are fitted (or contacted or opposed).
- the second columnar member 122 is stacked on the first columnar member 121 such that the first outer surface 121c of the first columnar member 121 and the first inner surface 122f of the second columnar member 122 are fitted (or contacted or opposed).
- the shape of the outer edges of the first upper surface 121a and the second lower surface 122g and the first outer surface 121c and the first inner surface 122f on the XY plane is square as described above. For this reason, when the second columnar member 122 is stacked on the first columnar member 121, the rotation of the second columnar member 122 around the Z axis with respect to the first columnar member 121 is suppressed. Furthermore, even after the second columnar member 122 is stacked on the first columnar member 121, the rotation of the second columnar member 122 around the Z axis with respect to the first columnar member 121 is suppressed.
- the welding member 121b is used as an adhesive for fixing the first columnar member 121 and the second columnar member 122, the welding member 121b is added to or in place of the first upper surface 121a. It may be formed on at least one of the lower surface 122g, the first outer surface 121c, and the first inner surface 122f.
- the cylindrical member 13 is fitted into the columnar member 12.
- the cylindrical member 13 is gradually fitted into the columnar member 12 so as to move from the + Z side toward the ⁇ Z side.
- the cylindrical member 13 is gradually fitted into the columnar member 12 by being pushed from the + Z side toward the ⁇ Z side using a tool (not shown).
- the columnar member 12 is substantially inserted into the cylinder of the cylindrical member 13 from the ⁇ Z side toward the + Z side when the cylindrical member 13 is pushed.
- the first inner surface 13b (for example, at least a part of the second inner surface part 13b-2) is fitted (or contacted or opposed) to at least a part of the first outer surface 122c.
- the second columnar member 122 is gradually fitted into the cylinder defined by the inner surface 13b.
- the cylindrical member 13 is made of a material having elasticity.
- the first inner surface 13b (and the first outer surface 13c) is directed outward so that the diameter of the first inner surface 13b is enlarged in the fitting surface where the first inner surface 13b and the outer surface 122c are fitted.
- the cylindrical member 13 is fitted into the columnar member 12 while expanding toward the top.
- the cylindrical member 13 has the four protrusions 13 e of the cylindrical member 13 and the four holes 122 d of the second columnar member 122 positioned on the same XY plane. Move towards the -Z side until it happens.
- the cylindrical member 13 moves until the four protrusions 13e and the four holes 122d are positioned on the same XY plane, the four protrusions 13e and the four holes 122d are fitted into each other. .
- the positional relationship between the columnar member 12 and the cylindrical member 13 is fixed by the fitting between the four protrusions 13e and the four holes 122d. As a result, the support device 1 is completed.
- “Fixing the positional relationship between the columnar member 12 and the cylindrical member 13” means that the cylindrical member 13 is moved relative to the columnar member 12, and the four protruding portions 13e and the four hole portions 122d are fitted. It means a state that is suppressed as compared to the case where they are not matched.
- “fixing the positional relationship between the columnar member 12 and the cylindrical member 13” means suppressing the rotation of the cylindrical member 13 around the Z axis with respect to the second columnar member 122 (or the columnar member 12). It may be.
- “Fixing the positional relationship between the columnar member 12 and the cylindrical member 13” means suppressing the movement of the cylindrical member 13 along the Z-axis with respect to the second columnar member 122 (or the columnar member 12). May be.
- the positional relationship between the columnar member 12 and the cylindrical member 13 is such that the first outer surface 122c of the second columnar member 122 and the cylinder in addition to or instead of the fitting of the four protrusions 13e and the four holes 122d. It may be fixed by the frictional force between the first member 13 and the first inner surface 13b. As described above, considering that the first inner surface 13b and the first outer surface 122c are relatively closely attached to each other, the first outer surface 122c of the second columnar member 122 and the first inner surface 13b of the cylindrical member 13 are used. The positional relationship between the columnar member 12 and the cylindrical member 13 can be fixed accordingly by the frictional force between the columnar member 12 and the cylindrical member 13.
- FIGS. 9A to 9E are cross-sectional views showing a cross section along the XZ plane of the support device 1 when the support device 1 of the first embodiment is used.
- a space SP1 surrounded by the first upper surface 122a, the second upper surface 122b, and the first inner surface portion 13b-1 (particularly, a space SP1 having a volume of a predetermined amount or more).
- An arbitrary holding object can be held in the space SP1.
- a desired liquid which is an example of a holding object, is dispensed into the space SP1, the desired liquid is held in the space SP1.
- the support device 1 can function as a so-called well plate.
- the cylindrical member 13 is made of an elastic material, the first inner surface 13b and the first outer surface 122c are relatively strongly in close contact with each other as described above.
- the space SP1 is secured on the + Z side with respect to the contact surface (that is, the fitting surface) between the first inner surface 13b and the first outer surface 122c.
- maintained in space SP1 is the 1st inner surface 13b. From the gap between the first outer surface 122c and the first outer surface 122c. That is, in the first embodiment, the water tightness of the space SP1 is ensured appropriately or suitably. Therefore, even when a desired liquid, which is an example of a holding object, is injected into the space SP1, the space SP1 can suitably hold the desired liquid.
- each cylindrical member 13 provided in the support device 1 is movable toward the ⁇ Z side.
- each cylindrical member 13 is movable toward the ⁇ Z side by being pushed down toward the ⁇ Z side by the jig 15.
- the jig 15 includes a bottom portion 15a and a tube portion 15b.
- the bottom 15a is a plate-like or disk-like member in plan view.
- the cylindrical portion 15b is a cylindrical member having one end (the end portion on the + Z side in the example shown in FIG. 9B) attached to the bottom portion 15a.
- the cylindrical portion 15 b is a member whose other end (in the example shown in FIG. 9B, the end portion on the ⁇ Z side) can contact the first upper surface 13 a of the cylindrical member 13.
- the inner diameter of the cylindrical portion 15 b on the XY plane is the same as the inner diameter of the first upper surface 13 a of the cylindrical member 13. In the jig 15, a space SP15 surrounded by the bottom portion 15a and the cylindrical portion 15b is secured.
- each projection 13e of the cylindrical member 13 and each hole 122d of the second columnar member 122 is released.
- each projection 13e is caused by the stress received from the first outer surface 122c of the second columnar member 122, as shown in FIG. Extruded outward.
- the cylindrical member 13 is distorted.
- the cylindrical member 13 is distorted so that a part of the first inner surface 13b not facing the first outer surface 122c is inclined inward.
- the shape of the first inner surface portion 13b-1 not facing the first outer surface 122c in the initial state in the first inner surface 13b is a tapered shape. Therefore, even when the tubular member 13 is distorted by the disengagement between the protrusions 13e and the holes 122d, the first inner surface 13b and the first outer surface 122c that are inclined toward the inner side. Will not be too close together. In other words, the frictional force between the first inner surface 13b and the first outer surface 122c inclined toward the inner direction does not become excessively strong.
- the tubular member 13 is distorted due to the disengagement between the projections 13e and the holes 122d.
- the cylindrical member 13 can move relatively smoothly toward the -Z side.
- each projection 13e is at a certain point in time than the first lower surface 122e of the second columnar member 122 ⁇ . It will be located on the Z side.
- the surface on which the protrusions 13e face each other along the XY plane changes from the first outer surface 122c of the second columnar member 122 to the second outer surface 121e of the first columnar member 121.
- the second outer surface 121e is positioned inward of the first outer surface 122c, and the distance between the first outer surface 122c and the second outer surface 121e along the XY plane is each protrusion along the XY plane.
- each protrusion 13e does not contact the second outer surface 121e.
- the frictional force between the cylindrical member 13 and the second columnar member 122 is reduced as compared with the case where each protrusion 13e is in contact with the first outer surface 122c. That is, the frictional force that hinders the movement of the cylindrical member 13 toward the ⁇ Z side is reduced. For this reason, the cylindrical member 13 can move relatively smoothly toward the ⁇ Z side.
- each protrusion 13e gradually contacts the third outer surface 121f having a tapered shape.
- the frictional force that hinders the movement of the tubular member 13 toward the ⁇ Z side is gradually increased as compared with the case where each protrusion 13e is not in contact with the third outer surface 121f. Accordingly, the movement of the cylindrical member 13 toward the ⁇ Z side is gradually suppressed. Therefore, the third outer surface 121f can act as a suppressing portion that suppresses the movement of the tubular member 13 toward the ⁇ Z side.
- each protrusion 13e comes into contact with the fourth outer surface 121g.
- the movement of the tubular member 13 toward the ⁇ Z side is prevented as compared with the case where each protrusion 13e is not in contact with the fourth outer surface 121g (for example, the case where it is in contact with the third outer surface 121f).
- the friction force is further increased. Therefore, the movement of the cylindrical member 13 toward the ⁇ Z side is further suppressed.
- the fourth outer surface 121g can act as a suppressing portion that suppresses the movement of the tubular member 13 toward the ⁇ Z side or a stop portion that stops the movement of the tubular member 13 toward the ⁇ Z side.
- the state in which the movement of the tubular member 13 toward the ⁇ Z side due to the protrusion 13e coming into contact with the fourth outer surface 121g is referred to as a “final state”.
- the first upper surface 122a of the second columnar member 122 is located on the + Z side with respect to the first upper surface 13a of the tubular member 13.
- the distance D from the first upper surface 122a to the first upper surface 13a is equal to or less than the predetermined distance D2.
- the length along the Z axis of the first inner surface 13b and the first outer surface 13c of the cylindrical member 13 is such that the distance D from the first upper surface 122a to the first upper surface 13a in the final state is equal to or less than the predetermined distance D2. Is the length that can be done.
- the third outer surface 121f and the fourth outer surface 121g are formed at positions where the distance D from the first upper surface 122a to the first upper surface 13a in the final state can be set to a predetermined distance D2 or less. Since the direction from the first upper surface 122a toward the + Z side is defined as a positive direction, in the example shown in FIG. 9E, the distance D from the first upper surface 122a to the first upper surface 13a is a negative distance. It has become.
- the space 15 is secured in the jig 15, so that the bottom 15 a of the jig 15 is placed on the first upper surface 122 a of the second columnar member 122. There is no contact. Alternatively, the bottom portion 15a of the jig 15 does not come into contact with the support object supported by the first upper surface 122a. For this reason, the 1st upper surface 122a (or support object) is protected suitably.
- the first upper surface 122a is positioned on the + Z side with respect to the first upper surface 13a. That is, the first upper surface 122 a is exposed from the cylindrical member 13. The first upper surface 122a is exposed from the inside of the cylindrical member 13. Therefore, any approaching object that should approach the first upper surface 122a (or the support object supported by the first upper surface 122a) approaches the first upper surface 122a without contacting the cylindrical member 13. Can do. That is, the cylindrical member 13 hardly or completely prevents the approaching object from approaching the first upper surface 122a (or the supporting object).
- FIGS. 10A to 10C are cross-sectional views showing a cross section along the XZ plane of the support device 1 when using the support device 1 of the first embodiment for supporting the biochip 14. .
- FIG. 10A shows an example in which the entire first upper surface 122a becomes the support region 122a-1.
- the biochip 14 may be attached to the support region 122a-1 using an adhesive such as a thermosetting resin.
- the support device 1 is in an initial state.
- the support device 1 may be in a state where the cylindrical member 13 is not fitted into the columnar member 12 at the time when the biochip 14 is attached. In this case, the cylindrical member 13 may be fitted into the columnar member 12 after the biochip 14 is attached.
- the object to be held is held against the space SP ⁇ b> 1 secured by the first upper surface 122 a and the second upper surface 122 b of the second columnar member 122 and the first inner surface 13 b of the cylindrical member 13.
- a liquid sample that is, a sample to be subjected to molecular diagnosis
- LQ which is an example of the object
- the support device 1 is in an initial state. Therefore, the support device 1 can suitably hold the sample LQ dispensed for reacting with the biochip 14 by using the space SP1. As a result, the reaction of the biochip 14 with respect to the sample LQ is promoted.
- the reaction of the biochip 14 to the sample LQ is optically detected by the measuring apparatus MS.
- the objective lens LS (see FIG. 24) provided in the measurement apparatus MS approaches the biochip 14 until the distance between the biochip 14 and the lens surface of the objective lens LS is equal to or less than the observable distance.
- the cylindrical member 14 is an arbitrary member between the time when the sample LQ is dispensed (or the time when the biochip 14 reacts with the sample LQ) and the time when the objective lens LS approaches the biochip 14. At this point, move to the -Z side.
- the support device 1 at any time after the sample LQ is dispensed (or after the biochip 14 reacts with the sample LQ) until the objective lens LS approaches the biochip 14. Transition from the initial state to the final state. For this reason, the objective lens LS can approach the biochip 14 without contacting the cylindrical member 13. In other words, the cylindrical member 13 hardly or completely obstructs the approach of the objective lens LS to the biochip 14.
- the distance from the first upper surface 122a to the first upper surface 13a in the final state In consideration of approaching the biochip 14 until the distance between the biochip 14 and the lens surface of the objective lens LS is equal to or less than the observable distance, the distance from the first upper surface 122a to the first upper surface 13a in the final state.
- the “predetermined distance D2” that defines D an arbitrary value less than or equal to the observable distance may be set.
- the measuring device MS irradiates the biochip 14 with illumination light in order to detect the reaction of the biochip 14. At least a part of the illumination light can be reflected by at least one of the upper surface of the biochip 14, the first upper surface 122a, and the second upper surface 122b. This reflected light can act as noise when the measurement device MS detects the reaction of the biochip 14. Therefore, it is preferable that the reflected light does not enter the objective lens LS as much as possible.
- the second upper surface 122b faces outward. Therefore, even if the illumination light is reflected by the second upper surface 122b, the reflected light from the second upper surface 122b propagates outward.
- the reflected light from the second upper surface 122b is less likely to enter the objective lens LS than when the second upper surface 122b is not directed outward.
- the first upper surface 122a of the second columnar member 122 is located on the + Z side with respect to the first upper surface 13a of the tubular member 13. Therefore, the reflected light from at least one of the upper surface of the biochip 14, the first upper surface 122a, and the second upper surface 122b is reflected by the first inner surface 13b of the cylindrical member 13 and enters the objective lens LS. Things are relatively less likely to occur. As described above, since the reflected light does not easily enter the objective lens LS, noise at the time of detecting the reaction of the biochip 14 by the measuring device MS is reduced.
- the support device 1 holds an arbitrary holding object (for example, the sample LQ) in the space SP1, and supports the supporting object (for example, the biochip 14) supported by the supporting device 1.
- An arbitrary target object for example, the objective lens LS
- the support device 1 holds an arbitrary holding object (for example, the sample LQ) in the space SP1, and supports the supporting object (for example, the biochip 14) supported by the supporting device 1.
- An arbitrary target object for example, the objective lens LS
- FIG. 9 (a) to FIG.9 (e) and FIG.10 (a) to FIG.10 (c) is an example. Therefore, a part of the usage method of the support device 1 may be appropriately modified. Hereinafter, an example of modification of the method of using the support device 1 will be described.
- the water tightness of the space SP1 is ensured by the close contact between the first inner surface 13b and the first outer surface 122c.
- the watertightness of the space SP1 may be ensured by the close contact between the hole 122d and the protrusion 13e in addition to or instead of the close contact between the first inner surface 13b and the first outer surface 122c.
- the hole 122d is continuously formed on the circumference corresponding to the outer edge of the first outer surface 122c on the XY plane. It may be.
- the protrusion 13e When the water tightness of the space SP1 is secured by the close contact between the hole 122d and the protrusion 13e, the protrusion 13e is continuously formed on the circumference corresponding to the outer edge of the first inner surface 13b on the XY plane. It may be. When the water tightness of the space SP1 is secured by the close contact between the hole 122d and the protrusion 13e, the first inner surface 13b and the first outer surface 122c may not be relatively firmly attached. When the water tightness of the space SP1 is ensured by the close contact between the hole 122d and the protrusion 13e, the first inner surface 13b and the first outer surface 122c may not be fitted or in contact with each other.
- the space SP15 secured in the jig 15 is a biochip in which the bottom surface 15a of the jig 15 is supported by the first upper surface 122a (or the first upper surface 122a) mainly when the cylindrical member 13 is pushed down to the ⁇ Z side. It is ensured for the purpose of preventing contact with a support object such as 14. However, when the bottom portion 15a of the jig 15 does not contact the first upper surface 122a (or the support object) when the cylindrical member 13 is pushed down to the ⁇ Z side, the space SP15 may not be secured. Good. In this case, for example, the jig 15 may not include the cylindrical portion 15b.
- the jig 15 can push down the cylindrical member 13 toward the ⁇ Z side, and when the cylindrical member 13 is pushed down to the ⁇ Z side, the first upper surface 122a (or the support object). Any structure may be used as long as it does not come into contact with ().
- the movement of the tubular member 13 toward the ⁇ Z side is caused by the protrusion 13e contacting the third outer surface 121f in addition to or instead of being stopped when the protrusion 13e contacts the fourth outer surface 121g. It may be stopped.
- the state where the movement toward the ⁇ Z side of the cylindrical member 13 is stopped by the protrusion 13e coming into contact with the third outer surface 121f may be the “final state”.
- the third outer surface 121f can act as a stop portion that stops the movement of the cylindrical member 13 toward the ⁇ Z side.
- the first upper surface 122a may be positioned on the ⁇ Z side with respect to the first upper surface 13a.
- the first upper surface 122 a may not be exposed from the tubular member 13.
- the distance D from the first upper surface 122a to the first upper surface 13a is not more than the predetermined distance D2. Therefore, any approaching object that should approach the first upper surface 122a (or the support object supported by the first upper surface 122a) approaches the first upper surface 122a without contacting the cylindrical member 13. Can do.
- each columnar member 12 included in the support device 1 may be movable toward the + Z side. Good. Even when each columnar member 12 moves toward the + Z side, the state of the support device 1 transitions from the initial state to the final state.
- the first columnar member 121 may not be integrated with the base member 11 or may not be integrally molded.
- the tubular member 13 may be integrated with the base member 11 or may be integrally formed.
- FIGS. 11 (a) to 11 (d) are cross-sectional views showing cross sections along the XZ plane of the first columnar member 121, the second columnar member 222, and the cylindrical member 23 provided in the support device 2 of the second embodiment.
- the support apparatus 2 of 2nd Embodiment mainly differs in the structure of the 2nd columnar member 222 and the cylindrical member 23 compared with the support apparatus 1 of 1st Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 1 of the first embodiment.
- the detailed description is abbreviate
- the support device 2 of the second embodiment includes a second columnar member 222 instead of the second columnar member 122 of the first embodiment.
- the second columnar member 222 includes a first upper surface 122a, a second upper surface 122b, a first outer surface 122c, four holes 122d, a first lower surface 122e, and a second lower surface. 122g.
- the second columnar member 222 includes a first inner surface 222f-1, a third lower surface 222f-2, and a second inner surface 222f-3 instead of the first inner surface 122f.
- the first inner surface 222f-1 is a surface extending from the outer edge of the first lower surface 122e toward the + Z side.
- the first inner surface 222f-1 is a surface facing the inner direction.
- the first inner surface 222f-1 is a surface parallel to the Z axis.
- the shape of the outer edge of the first inner surface 222f-1 on the XY plane is a circle.
- the center of the first inner surface 222f-1 on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 122a on the XY plane.
- the third lower surface 222f-2 is a surface extending inward from the outer edge on the + Z side of the first inner surface 222f-1.
- the third lower surface 222f-2 is a surface facing the -Z side.
- the third lower surface 222f-2 is a surface parallel to the XY plane.
- the shape of the outer edge of the third lower surface 222f-2 on the XY plane in the outer direction is a circle.
- the shape of the outer edge in the inner direction of the third lower surface 222f-2 on the XY plane is a square.
- the center of the third lower surface 222f-2 on the XY plane (that is, the center of a circle or a square) coincides with the center of the first upper surface 122a on the XY plane.
- the second inner surface 222f-3 is a surface extending from the outer edge in the inner direction of the third lower surface 222f-2 toward the + Z side.
- the second inner surface 222f-3 is a surface facing the inner direction.
- the second inner surface 222f-3 is a surface inclined with respect to the Z axis.
- the second inner surface 222f-3 is inclined with respect to the Z axis so that the diameter of the second inner surface 222f-3 on the XY plane increases toward the ⁇ Z side.
- the shape of the second inner surface 222f-3 is a tapered shape.
- the shape of the outer edge of the second inner surface 222f-3 on the XY plane is a square.
- the center of the second inner surface 222f-3 on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 122a on the XY plane.
- each of the four holes 122d is formed at a position closer to the first lower surface 122e than to the second upper surface 122b.
- Each of the four hole portions 122d has a distance between the four hole portions 122d along the Z axis and the first lower surface 122e between the four hole portions 122d along the Z axis and the second upper surface 122b. It is formed at a position that becomes smaller.
- Each of the four hole portions 122d is formed in a partial region of the first outer surface 122c facing the first inner surface 222f-1 along the XY plane.
- Each of the four holes 122d is formed in a partial region of the first outer surface 122c located on the ⁇ Z side with respect to the third lower surface 222f-2.
- the support device 2 of the second embodiment includes a cylindrical member 23 instead of the cylindrical member 13 of the first embodiment. Similar to the cylindrical member 13, the cylindrical member 23 includes a first upper surface 13a, a first inner surface 13b, a first outer surface 13c, a first lower surface 13d, and four protrusions 13e.
- the second member 23 includes a first portion 23-1 and a second portion 23-2.
- the first portion 23-1 is a part of the second member 23 including a region where the four protrusions 13e are formed.
- the second portion 23-2 is another part of the second member 23 that does not include the region where the four protrusions 13e are formed.
- the first part 23-1 is a part of the second member 23 located on the ⁇ Z side with respect to the second part 23-2.
- the second portion 23-2 is another portion of the second member 23 located on the + Z side with respect to the first portion 23-1.
- the first part 23-1 and the second part 23-2 are divided into relative parts derived from the presence / absence of the area where the four protrusions 13e are formed and the relative positional relationship along the Z axis. If it is a simple division, it is sufficient.
- the thickness of at least a part of the first portion 23-1 is the thickness of the second portion 23-2 (that is, along the direction orthogonal to the Z axis). Thinner than the length).
- the depression 23c-1 is formed on the first outer surface 13c of the first portion 23-1, so that the thickness of the first portion 23-1 is equal to the thickness of the second portion 23-2. It is thinner than that.
- the recess 23c-1 is a recess (or a hole or a recess) that is recessed inward from the first outer surface 13c.
- the support apparatus 2 of 2nd Embodiment is provided with the 1st columnar member 121 similarly to the support apparatus 1 of 1st Embodiment.
- FIG.11 (c) has shown the initial state of the support apparatus 2 of 2nd Embodiment.
- the second inner surface 222f-3 of the second columnar member 222 has at least the first outer surface 121c of the first columnar member 121 when the first columnar member 121 and the second columnar member 222 are fixed. It is a surface that can be fitted with (or can be contacted with or opposed to) a part.
- the inclination angle of the second inner surface 222f-3 with respect to the Z axis is the same as the inclination angle of the first outer surface 121c with respect to the Z axis.
- the shape of the outer edge of the second inner surface 222f-3 on the XY plane is the same as the shape of the outer edge of the first outer surface 121c on the XY plane.
- the diameter of the second inner surface 222f-3 on the XY plane is the same as that of the first outer surface 121c on the XY plane. It is the same as the diameter (however, a margin that can be fitted or an error caused by fitting accuracy may be considered).
- the first inner surface 222f-1 of the second columnar member 222 is not in contact (or fitted) with the first outer surface 121c of the first columnar member 121. However, the first inner surface 222f-1 of the second columnar member 222 faces the first outer surface 121c along the XY plane.
- a space SP2 is secured between the first inner surface 222f-1 and the first outer surface 121c.
- a space SP2 is secured among the first inner surface 222f-1, the first outer surface 121c, and the third lower surface 222f-2.
- the space SP2 is secured in the inner direction of the first outer surface 121c.
- each cylindrical member 23 included in the support device 2 is movable toward the ⁇ Z side with reference to the support device 2 in such an initial state.
- the fitting between each projection 13e of the cylindrical member 13 and each hole 122d of the second columnar member 122 is released.
- At least a part of the second columnar member 222 surrounded by the first outer surface 122c, the first lower surface 122e, and the first inner surface 222f-1 is such that at least a part of the second columnar member 222 enters the space SP2. Then, it bends inward. As a result, the frictional force between each protrusion 13e or the first inner surface 13b and the first outer surface 122c is smaller than when at least a part of the second columnar member 222 is not bent inward. . That is, the frictional force that hinders the movement of the cylindrical member 23 toward the ⁇ Z side is reduced. Therefore, the cylindrical member 23 can move relatively smoothly toward the ⁇ Z side.
- each protrusion 13e is pushed outward by the stress received from the first outer surface 122c.
- the first portion 23-1 including the region where the four protrusions 13e are formed is pushed outward by the stress received from the first outer surface 122c.
- the depression 23c-1 is formed in the first outer surface 13c of the first portion 23-1 (that is, the first portion 23-1 is relatively thin), and therefore, as shown in FIG. As described above, at least a part of the first portion 23-1 bends in the outward direction.
- the frictional force between each protrusion 13e or the first inner surface 13b and the first outer surface 122c is smaller than when at least a part of the first portion 23-1 is not bent outward. Become. That is, the frictional force that hinders the movement of the cylindrical member 23 toward the ⁇ Z side is reduced. Therefore, the cylindrical member 23 can move relatively smoothly toward the ⁇ Z side.
- the support device 2 according to the second embodiment further improves the tubular member 23 toward the ⁇ Z side while enjoying the various effects that the support device 1 according to the first embodiment can enjoy. It can be moved smoothly.
- At least a part of the first inner surface 222f-1 may be a surface inclined with respect to the Z axis. At least a part of the first inner surface 222f-1 may be a curved surface.
- the shape of the outer edge of the first inner surface 222f-1 on the XY plane may be a shape different from a circle (for example, an arbitrary polygon).
- the center of the first inner surface 222f-1 on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least a part of the third lower surface 222f-2 may be a surface inclined with respect to the XY plane. At least a part of the third lower surface 222f-2 may be a curved surface.
- the shape of the outer edge of the third lower surface 222f-2 on the XY plane in the outer direction may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the shape of the outer edge in the inner direction of the third lower surface 222f-2 on the XY plane may be a shape different from a square (for example, an arbitrary polygon, circle, or ellipse).
- the center of the third lower surface 222f-2 on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least a part of the second inner surface 222f-3 may be a surface parallel to the Z axis. At least a part of the second inner surface 222f-3 may be a curved surface. The shape of at least a part of the second inner surface 222f-3 may not be a tapered shape. The shape of the outer edge of the second inner surface 222f-3 on the XY plane may be a shape different from a square (for example, an arbitrary circle or polygon). The center of the second inner surface 222f-3 on the XY plane may not coincide with the center of the first upper surface 122a on the XY plane.
- At least one of the four holes 122d may be formed at a position closer to the second upper surface 122b than the first lower surface 122e. At least one of the four holes 122d has a distance between the at least one hole 122d along the Z axis and the first lower surface 122e from the at least one hole 122d along the Z axis. It may be formed at a position that is at least the distance between the two upper surfaces 122b.
- At least one of the four holes 122d may be formed in another partial region of the first outer surface 122c that does not face the first inner surface 222f-1 along the XY plane. At least one of the four holes 122d may be formed in another partial region of the first outer surface 122c located on the + Z side with respect to the third lower surface 222f-2.
- the second member 23 may not include at least one of the first portion 23-1 and the second portion 23-2.
- the thickness of the first portion 23-1 may be greater than or equal to the thickness of the second portion 23-2.
- the recess 23c-1 may not be formed on the first outer surface 13c of the first portion 23-1.
- At least a part of the second inner surface 222f-3 of the second columnar member 222 is fitted to the first outer surface 121c of the first columnar member 121 when the first columnar member 121 and the second columnar member 222 are fixed ( Alternatively, it may not be in contact or opposite.
- the inclination angle of at least a part of the second inner surface 222f-3 with respect to the Z axis may be different from the inclination angle of the first outer surface 121c with respect to the Z axis.
- the shape of the outer edge of at least a part of the second inner surface 222f-3 on the XY plane may be different from the shape of the outer edge of the first outer surface 121c on the XY plane.
- At least a part of the first inner surface 222f-1 of the second columnar member 222 may be in contact (or fitted) with the first outer surface 121c of the first columnar member 121. In the initial state, the space SP2 may not be ensured between the first inner surface 222f-1 and the first outer surface 121c.
- FIGS. 12 (a) to 12 (d) are cross-sectional views showing cross sections along the XZ plane of the first columnar member 321, the second columnar member 121, and the cylindrical member 13 provided in the support device 3 of the third embodiment. It is.
- the support apparatus 3 of 3rd Embodiment differs in the structure of the 1st columnar member 321 mainly compared with the support apparatus 1 of 1st Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 1 of the first embodiment.
- the support device 3 of the third embodiment includes a first columnar member 321 instead of the first columnar member 121 of the first embodiment.
- the first columnar member 321 includes a first upper surface 121a, a welding member 121b, a first outer surface 121c, a second upper surface 121d, a second outer surface 121e, and a first lower surface 121h.
- a first inner surface 121i, a second lower surface 121j, and a second inner surface 121k is a first inner surface 121i, a second lower surface 121j, and a second inner surface 121k.
- the first columnar member 321 of the third embodiment does not include the third outer surface 121f and the fourth outer surface 121g. Therefore, in the third embodiment, the second outer surface 121e is a surface extending from the fifth surface 115 (particularly, the lower surface 115b) of the base member 11 toward the + Z side.
- the support apparatus 3 of 3rd Embodiment is equipped with the 2nd columnar member 122 and the cylindrical member 13 similarly to the support apparatus 1 of 1st Embodiment.
- FIG.12 (b) has shown the initial state of the support apparatus 3 of 3rd Embodiment.
- the initial state of the support device 3 of the third embodiment is that of the support device 1 of the first embodiment, except that the first columnar member 321 does not include the third outer surface 121f and the fourth outer surface 121g. It is the same as the initial state. For this reason, the description of the initial state of the support device 3 of the third embodiment is omitted.
- each cylindrical member 13 included in the support device 3 is movable toward the ⁇ Z side with reference to the support device 3 in such an initial state.
- the fitting between each projection 13e of the cylindrical member 13 and each hole 122d of the second columnar member 122 is released.
- each protrusion 13e is at a certain point more than the first lower surface 122e of the second columnar member 122. It will be located on the Z side. For this reason, as in the first embodiment, the frictional force that hinders the movement of the cylindrical member 13 toward the ⁇ Z side is reduced. For this reason, the cylindrical member 13 can move relatively smoothly toward the ⁇ Z side.
- the first columnar member 321 does not include the third outer surface 121f and the fourth outer surface 121g. For this reason, as shown in FIG. 12D, even if the cylindrical member 13 further moves toward the ⁇ Z side, each protrusion 13e and the first inner surface 13b do not contact the first columnar member 321. Absent. That is, in the third embodiment, after each protrusion 13e moves to the ⁇ Z side with respect to the first lower surface 122e, the cylindrical member 13 can move more smoothly toward the ⁇ Z side.
- the movement of the tubular member 13 toward the ⁇ Z side is stopped when the first lower surface 13 d of the tubular member 13 hits the lower surface 115 b of the base member 11. .
- the movement of the tubular member 13 toward the ⁇ Z side may be stopped by other methods.
- the support device 3 according to the third embodiment further improves the tubular member 23 toward the ⁇ Z side while enjoying the various effects that the support device 1 according to the first embodiment can enjoy. It can be moved smoothly.
- FIGS. 13A to 13C are cross-sectional views showing cross sections along the XZ plane of the first columnar member 321, the second columnar member 422, and the cylindrical member 43 provided in the support device 4 of the fourth embodiment. It is.
- the support apparatus 4 of 4th Embodiment differs in the structure of the 1st columnar member 321, the 2nd columnar member 422, and the cylindrical member 43 compared with the support apparatus 1 of 1st Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 1 of the first embodiment.
- the support device 4 of the fourth embodiment includes a second columnar member 422 instead of the second columnar member 122 of the first embodiment. Similar to the second columnar member 122, the second columnar member 422 includes a first upper surface 122a, a second upper surface 122b, a first outer surface 122c, a first lower surface 122e, a first inner surface 122f, and a second lower surface 122g. And. Particularly in the fourth embodiment, the second columnar member 422 does not include the four holes 122d.
- the support device 4 of the fourth embodiment includes a cylindrical member 43 instead of the cylindrical member 13 of the first embodiment. Similar to the cylindrical member 13, the cylindrical member 43 includes a first upper surface 13a, a first inner surface 13b, a first outer surface 13c, and a first lower surface 13d.
- the cylindrical member 43 does not include the four protrusions 13e.
- the cylindrical member 43 includes a second inner surface 43f and a second upper surface 43g.
- the second inner surface 43f is a surface extending toward the ⁇ Z side from the inner edge of the first lower surface 13d.
- the second inner surface 43f is a surface located in the inner side direction than the first inner surface 13b.
- the second inner surface 43f is a surface facing the inner direction.
- the second inner surface 43f is a surface parallel to the Z axis.
- the shape of the outer edge of the second inner surface 43f on the XY plane is a circle.
- the center of the second inner surface 43f on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 13a on the XY plane.
- the second upper surface 43g is a surface extending outward from the outer edge on the + Z side of the second inner surface 43f.
- the second upper surface 43g is a surface extending inward from the outer edge on the ⁇ Z side of the first inner surface 13b (particularly, the second inner surface portion 13b-2).
- the second upper surface 43g is a surface facing the + Z side.
- the second upper surface 43g is a surface parallel to the XY plane.
- the shape of the outer edge in the inner direction and the outer direction of the second upper surface 43g on the XY plane is a circle.
- the center of the second upper surface 43g on the XY plane (that is, the center of the circle) coincides with the center of the first upper surface 13a on the XY plane.
- the support apparatus 4 of 4th Embodiment is provided with the 1st columnar member 321 similarly to the support apparatus 3 of 3rd Embodiment.
- FIG.13 (c) has shown the initial state of the support apparatus 4 of 4th Embodiment.
- at least a part of the second inner surface 43f of the cylindrical member 43 is a surface that can be fitted (or can be contacted or opposed) to at least a part of the second outer surface 121e of the first columnar member 321. It is.
- the shape of the outer edge of the second inner surface 43f on the XY plane is the same as the shape of the outer edge of the second outer surface 121e on the XY plane.
- the diameter of the second inner surface 43f on the XY plane is the same as the diameter of the second outer surface 121e on the XY plane ( However, a margin that can be fitted or an error caused by fitting accuracy may be considered).
- the positional relationship between the columnar member 42 and the cylindrical member 43 in the initial state is the friction between the first outer surface 122 c of the second columnar member 422 and the first inner surface 13 b of the cylindrical member 43. It is fixed by at least one of the force and the frictional force between the second inner surface 43 f of the cylindrical member 43 and the second outer surface 121 e of the first columnar member 321.
- the second upper surface 43g of the cylindrical member 43 may or may not be in contact with the first lower surface 122e of the second columnar member 422.
- each cylindrical member 43 provided in the support device 4 is movable toward the ⁇ Z side with reference to the support device 4 in such an initial state. Therefore, the support device 4 of the fourth embodiment can enjoy various effects that can be enjoyed by the support device 1 of the first embodiment described above.
- the second columnar member 422 may not include at least one of the second inner surface 43f and the second upper surface 43g.
- At least a part of the second inner surface 43f may be a surface inclined with respect to the Z axis. At least a part of the second inner surface 43f may be a curved surface. At least a part of the second inner surface 43f may be a surface located in the outer side direction than the first inner surface 13b.
- the shape of at least a part of the second inner surface 43f on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or an ellipse).
- the center of the second inner surface 43f on the XY plane may not coincide with the center of the first upper surface 13a on the XY plane.
- At least a part of the second upper surface 43g may be a surface inclined with respect to the XY plane.
- the shape of the outer edge of at least one of the inner and outer directions of the second upper surface 43g on the XY plane may be a shape different from a circle (for example, an arbitrary polygon or ellipse).
- the center of the second upper surface 43g on the XY plane may not coincide with the center of the first upper surface 13a on the XY plane.
- the second inner surface 43f of the cylindrical member 43 may not be fitted (or contacted or opposed) to the second outer surface 121e of the first columnar member 321.
- the shape of at least a part of the second inner surface 43f on the XY plane may be the same as the shape of at least a part of the second outer surface 121e on the XY plane.
- FIG. 14A is a plan view of the first columnar member 521 provided in the support device 5 of the fifth embodiment observed from the + Z side.
- FIG. 14B is a sectional view taken along line XIV-XIV ′ of the first columnar member 521 shown in FIG. 14C to 14D are cross-sectional views showing cross sections along the XZ plane of the first columnar member 521, the second columnar member 422, and the cylindrical member 43 provided in the support device 5 of the fifth embodiment. It is.
- the support apparatus 5 of 5th Embodiment mainly differs in the structure of the 1st columnar member 521 compared with the support apparatus 4 of 4th Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 4 of the fourth embodiment.
- the detailed description is abbreviate
- the support device 5 of the fifth embodiment includes a first columnar member 521 instead of the first columnar member 321 of the fourth embodiment. Similar to the first columnar member 321, the first columnar member 521 includes a first upper surface 121a, a welding member 121b, a first outer surface 121c, a second upper surface 121d, a second outer surface 121e, and a first lower surface 121h. , A first inner surface 121i, a second lower surface 121j, and a second inner surface 121k.
- the first columnar member 521 includes two protrusions 521m.
- Each of the two protrusions 521m is a protrusion formed on the second outer surface 121e.
- Each of the two protrusions 521m is a protrusion protruding outward from the second outer surface 121e.
- the two protrusions 521m are formed so as to be positioned on the same XY plane.
- the two protrusions 521m are formed so as to be arranged at equal intervals on a circumference corresponding to the outer edge of the second outer surface 121e on the XY plane.
- the support apparatus 5 of 5th Embodiment is provided with the 2nd columnar member 422 and the cylindrical member 43 similarly to the support apparatus 4 of 4th Embodiment.
- each of the two protrusions 521m is a member that can contact the first lower surface 13d of the cylindrical member 43.
- Each of the two protrusions 521m is a member that can support the first lower surface 13d from the ⁇ Z side. As a result, the two protrusions 521m can fix the positional relationship between the columnar member 52 and the cylindrical member 43 in the initial state.
- the positional relationship between the columnar member 52 and the cylindrical member 43 is the second
- the first outer surface 122c of the columnar member 422 and the first inner surface 13b of the cylindrical member 43 may not be fixed by a frictional force. In this case, the first outer surface 122c and the first inner surface 13b may not be fitted (or contacted or opposed).
- the positional relationship between the columnar member 52 and the cylindrical member 43 is not fixed by the frictional force between the second inner surface 43f of the cylindrical member 43 and the second outer surface 121e of the first columnar member 321. Also good. In this case, the second inner surface 43f and the second outer surface 121e may not be fitted (or contacted or opposed).
- each cylindrical member 43 provided in the support device 5 is movable toward the ⁇ Z side with reference to the support device 5 in such an initial state.
- the first lower surface 13d of the cylindrical member 43 gets over the two projecting portions 521m and becomes ⁇ Z Move towards the side.
- the cylindrical member 23 can move relatively smoothly toward the ⁇ Z side as compared with the case where the outer end surfaces of the two protrusions 521m are in contact with the first inner surface 13b.
- at least one of the two protruding portions 521m may be in contact with the first inner surface 13b at the end face in the outer direction.
- the support device 5 of the fifth embodiment can enjoy various effects that can be enjoyed by the support device 4 of the fourth embodiment described above.
- the 1st columnar member 521 demonstrated using FIG. 14 (a) to FIG.14 (d) is an example. Therefore, a part of the configuration of the first columnar member 521 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the first columnar member 521 will be described.
- One of the two protrusions 521m may be formed on another XY plane different from the XY plane on which the other protrusion 521m is positioned.
- the two protrusions 521m may be formed so as to be different or arranged at an arbitrary interval on a circumference corresponding to the outer edge of the second outer surface 121e on the XY plane.
- the first columnar member 521 may include one or three or more protrusions 521m.
- FIGS. 15 (a) to 15 (d) are cross-sectional views showing cross sections along the XZ plane of the first columnar member 121, the second columnar member 622, and the cylindrical member 63 provided in the support device 6 of the sixth embodiment. It is.
- the support device 6 of 6th Embodiment differs in the structure of the 2nd columnar member 622 and the cylindrical member 63 mainly compared with the support device 1 of 1st Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 1 of the first embodiment.
- the support device 6 of the sixth embodiment includes a second columnar member 622 instead of the second columnar member 122 of the first embodiment. Similar to the second columnar member 122, the second columnar member 622 includes a first upper surface 122a, a second upper surface 122b, a first lower surface 122e, and a second lower surface 122g.
- the second columnar member 622 does not include the four holes 122d.
- the second columnar member 622 includes a first outer surface 622c instead of the first outer surface 122c included in the second columnar member 122.
- the first outer surface 622c is a surface inclined with respect to the Z axis in that it is inclined with respect to the Z axis so that the diameter of the first outer surface 622c becomes smaller toward the ⁇ Z side. It is different from the first outer surface 122c which may not be.
- Other features of the first outer surface 622c may be the same as other features of the first outer surface 122c.
- the support device 6 of the sixth embodiment includes a cylindrical member 63 instead of the cylindrical member 13 of the first embodiment. Similar to the cylindrical member 13, the cylindrical member 63 includes a first upper surface 13 a and a first lower surface 13 d.
- the cylindrical member 63 does not include the four protrusions 13e. Furthermore, the cylindrical member 63 includes a first inner surface 63b and a first outer surface 63c instead of the first inner surface 13b and the first outer surface 13c included in the cylindrical member 13.
- the first inner surface 63b is a surface inclined with respect to the Z axis in that it is inclined with respect to the Z axis so that the diameter of the first inner surface 63b becomes smaller toward the ⁇ Z side. It is different from the first inner surface 13b which may not be. Other features of the first inner surface 63b may be the same as other features of the first inner surface 13b.
- the first outer surface 63c is a surface inclined with respect to the Z axis in that it is inclined with respect to the Z axis so that the diameter of the first outer surface 63c becomes smaller toward the ⁇ Z side. It is different from the first outer surface 13c which may not be. Other features of the first outer surface 63c may be the same as other features of the first outer surface 13c.
- the support apparatus 6 of 6th Embodiment is provided with the 1st columnar member 121 similarly to the support apparatus 1 of 1st Embodiment.
- FIG.15 (c) has shown the initial state of the support apparatus 6 of 6th Embodiment.
- the first inner surface 63b of the cylindrical member 63 can be fitted (or contactable) with the first outer surface 622c of the second columnar member 622 when the cylindrical member 63 is fitted into the columnar member 62. It is a surface that can be opposed). For this reason, the inclination angle with respect to the Z axis of the first inner surface 63b is the same as the inclination angle of the first outer surface 622c with respect to the Z axis.
- the manner of fitting between the first inner surface 63b and the first outer surface 622c is the same as the manner of fitting between the first inner surface 13b and the first outer surface 122c, and thus detailed description thereof is omitted.
- the positional relationship between the columnar member 62 and the cylindrical member 63 in the initial state is fixed by the frictional force between the first outer surface 622c and the first inner surface 63b.
- the distance D from the first upper surface 122a of the second columnar member 622 to the first upper surface 13a of the cylindrical member 63 is equal to or greater than the predetermined distance D1. Accordingly, the diameter D of the first outer surface 622c and the first inner surface 63b on the XY plane and the inclination angle of the first outer surface 622c and the first inner surface 63b with respect to the Z axis are such that the distance D in the initial state is equal to or greater than the predetermined distance D1. Designed properly.
- the diameter of the first outer surface 622c and the first inner surface 63b on the XY plane and the inclination angle of the first outer surface 622c and the first inner surface 63b with respect to the Z axis are the same as the cylindrical member 63 and the columnar shape in the state shown in FIG. Appropriately designed to mate with member 62.
- each cylindrical member 63 is movable toward the ⁇ Z side with reference to the support device 6 in such an initial state.
- each of the first outer surface 622c and the first inner surface 63b is inclined with respect to the Z axis so that the diameter decreases toward the ⁇ Z side. For this reason, as shown in FIG. 15D, when each cylindrical member 63 moves toward the ⁇ Z side with reference to the support device 6 in the initial state, the first outer surface 622c and the first inner surface 63b are fitted to each other. Comes off.
- the support device 6 of the sixth embodiment further improves the tubular member 63 toward the ⁇ Z side while enjoying various effects that can be enjoyed by the support device 1 of the first embodiment described above. It can be moved smoothly.
- FIGS. 16 (a) to 16 (c) are cross-sectional views showing cross sections along the XZ plane of the first columnar member 121, the second columnar member 622, and the cylindrical member 73 provided in the support device 7 of the seventh embodiment. It is.
- the support apparatus 7 of 7th Embodiment mainly differs in the structure of the cylindrical member 73 compared with the support apparatus 6 of 6th Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 6 of the sixth embodiment.
- the support device 7 of the seventh embodiment includes a cylindrical member 73 instead of the cylindrical member 63 of the sixth embodiment.
- the cylindrical member 73 includes a first cylindrical member 73-1 and a second cylindrical member 73-2.
- the first cylindrical member 73-1 includes a first upper surface 13a-1, a first inner surface 63b-1, a first outer surface 63c-1, and a first lower surface 13d-1.
- the second cylindrical member 73-2 includes a first upper surface 13a-2, a first inner surface 63b-2, a first outer surface 63c-2, and a first lower surface 13d-2.
- the characteristics of the first upper surface 13a-1 and the first upper surface 13a-2 are the same as the characteristics of the first upper surface 13a of the sixth embodiment.
- the features of the first inner surface 63b-1 and the first inner surface 63b-2 are the same as the features of the first inner surface 63b of the sixth embodiment.
- the characteristics of the first outer surface 63c-1 and the first outer surface 63c-2 are the same as the characteristics of the first outer surface 63c of the sixth embodiment.
- the features of the first lower surface 13d-1 and the first lower surface 13d-2 are the same as the features of the first lower surface 13d of the sixth embodiment.
- FIG. 16A shows the tubular member 73 when the support device 7 is in the initial state.
- the first inner surface 63b-1 of the first cylindrical member 73-1 can be fitted to the first outer surface 63c-2 of the second cylindrical member 73-2.
- the inclination angle of the first inner surface 63b-1 with respect to the Z axis is the same as the inclination angle of the first outer surface 63c-2 with respect to the Z axis.
- the first upper surface 13a-1 of the first cylindrical member 73-1 is in contact with the second cylindrical member 73-2. It is located on the + Z side with respect to the first upper surface 13a-2.
- the first lower surface 13d-1 of the first cylindrical member 73-1 is in contact with the second cylindrical member 73-2. It is located on the + Z side with respect to the first lower surface 13d-2. Accordingly, the diameters of the first inner surface 63b-1 and the first outer surface 63c-2 on the XY plane and the inclination angles of the first inner surface 63b-1 and the first outer surface 63c-2 with respect to the Z axis are shown in FIG. Appropriately designed to realize the state.
- the diameters of the first inner surface 63b-1 and the first outer surface 63c-2 on the XY plane and the inclination angles of the first inner surface 63b-1 and the first outer surface 63c-2 with respect to the Z axis are shown in FIG. In this state, the first inner surface 63b-1 and the first outer surface 63c-2 are appropriately designed.
- the support apparatus 7 of 7th Embodiment is provided with the 1st columnar member 121 and the 2nd columnar member 622 similarly to the support apparatus 6 of 6th Embodiment.
- FIG. 16B shows an initial state of the support device 7 of the seventh embodiment.
- the first inner surface 63b-2 of the second cylindrical member 73-2 can be fitted to the first outer surface 622c of the second columnar member 622 when the cylindrical member 73 is fitted into the columnar member 62. It is a surface that can contact (or can contact).
- the manner of fitting the first inner surface 63b-2 and the first outer surface 622c in the seventh embodiment is the same as the manner of fitting the first inner surface 63b and the first outer surface 622c in the sixth embodiment. Therefore, the detailed description is abbreviate
- the distance D from the first upper surface 122a of the second columnar member 622 to the first upper surface 13a-1 of the first cylindrical member 73-1 is equal to or greater than the predetermined distance D1. Accordingly, the diameter D of the first outer surface 622c and the first inner surface 63b-2 on the XY plane and the inclination angle of the first outer surface 622c and the first inner surface 63b-2 with respect to the Z axis are such that the initial distance D is equal to or greater than the predetermined distance D1.
- the diameter of the first outer surface 622c and the first inner surface 63b-2 on the XY plane and the inclination angle of the first outer surface 622c and the first inner surface 63b-2 with respect to the Z axis are cylindrical in the state shown in FIG. It is designed appropriately so that the member 73 and the columnar member 62 are fitted. Further, the diameters of the first inner surface 63b-1 and the first outer surface 63c-2 on the XY plane and the inclination angles of the first inner surface 63b-1 and the first outer surface 63c-2 with respect to the Z axis are also shown in FIG. The cylindrical member 73 and the columnar member 62 are appropriately designed so as to fit in the state shown in FIG.
- each cylindrical member 73 is movable toward the ⁇ Z side with reference to the support device 7 in such an initial state.
- each of the first cylindrical member 73-1 and the second cylindrical member 73-2 constituting the cylindrical member 73 is movable toward the -Z side.
- each movement of the first cylindrical member 73-1 and the second cylindrical member 73-2 will be described in order.
- each of the first inner surface 63b-1 and the first outer surface 63c-2 is inclined with respect to the Z axis so that the diameter decreases toward the ⁇ Z side. Therefore, as shown in FIG. 16C, when the first cylindrical member 73-1 moves toward the ⁇ Z side with reference to the support device 7 in the initial state, the first inner surface 63b-1 and the first outer surface The fitting with 63c-2 is released. That is, when the first cylindrical member 73-1 moves toward the ⁇ Z side with reference to the support device 7 in the initial state, the first inner surface 63b-1 and the first outer surface 63c-2 do not come into contact with each other.
- the frictional force between the first inner surface 63b-1 and the first outer surface 63c-2 becomes small or zero. That is, the frictional force that hinders the movement of the first cylindrical member 73-1 toward the -Z side becomes small or zero. Therefore, the first tubular member 73-1 can move relatively smoothly toward the -Z side.
- each of the first outer surface 622c and the first inner surface 63b-2 is inclined with respect to the Z axis so that the diameter decreases toward the ⁇ Z side. Therefore, as shown in FIG. 16C, when the second cylindrical member 73-2 moves toward the ⁇ Z side with reference to the support device 7 in the initial state, the first outer surface 622c and the first inner surface 63b— 2 is disengaged. That is, when the second cylindrical member 73-2 moves toward the ⁇ Z side with respect to the support device 7 in the initial state, the first outer surface 622c and the first inner surface 63b-2 do not come into contact with each other.
- the frictional force between the first outer surface 622c and the first inner surface 63b-2 becomes small or zero. That is, the frictional force that hinders the movement of the second cylindrical member 73-2 toward the ⁇ Z side becomes small or zero. Therefore, the second cylindrical member 73-2 can move relatively smoothly toward the -Z side.
- the support device 7 according to the seventh embodiment further improves the tubular member 73 toward the ⁇ Z side while enjoying the various effects that the support device 1 according to the first embodiment can enjoy. It can be moved smoothly.
- the length (so-called height) of the cylindrical member 73 in the final state is relatively small.
- the support device 7 of the seventh embodiment as compared with the support device 6 of the sixth embodiment including the cylindrical member 63 configured by a single member, FIG. As can be seen by comparing (c), the length of the cylindrical member 73 in the final state in the Z-axis direction is reduced.
- the first upper surface 122a can be exposed from the cylindrical member 73. Specifically, the first upper surface 122a is exposed from the tubular member 73 in the final state even if the length along the Z-axis of the first columnar member 121 is reduced compared to the support device 6 of the sixth embodiment. Is possible. For this reason, size reduction of the support apparatus 7 can be achieved.
- the cylindrical member 73 is composed of two members (that is, the first cylindrical member 73-1 and the second cylindrical member 73-2).
- the cylindrical member 73 may be composed of three or more members.
- the three or more members constituting the cylindrical member 73 are combined in a manner similar to the case where the cylindrical member 73 is constituted by two members. It is done.
- FIG. 17A is a plan view of the cylindrical member 13 provided in the support device 8 according to the eighth embodiment observed from the + Z side.
- FIG. 17B is a sectional view taken along the line XVII-XVII ′ of the cylindrical member 13 shown in FIG.
- the support apparatus 8 of 8th Embodiment mainly differs in the structure of the cylindrical member 13 compared with the support apparatus 1 of 1st Embodiment.
- the description will be focused on a configuration different from the configuration of the support device 1 of the first embodiment.
- the detailed description is abbreviate
- a plurality of (24 in the example shown in FIG. 17A) cylindrical members 13 included in the support device 8 are integrated or connected.
- the 24 connecting members 13 are connected via connecting members 831 and 832.
- the connecting member 831 is a member that connects the outer surfaces 13c of two cylindrical members 13 adjacent along the X axis.
- the connecting member 832 is a member that connects the outer surfaces 13c of two cylindrical members 13 adjacent along the Y axis.
- Such a support device 8 of the eighth embodiment can enjoy various effects that can be enjoyed by the support device 1 of the first embodiment described above. Furthermore, in the eighth embodiment, since 24 cylindrical members 13 are connected, all the cylindrical members 13 included in the support device 8 are pushed down together by the same jig 15 so that all the cylindrical members 13 are pressed. The member 13 can be moved together. Furthermore, the plurality of cylindrical members 13 can be manufactured collectively by integrally molding the plurality of cylindrical members 13 together.
- FIG. 18A is a plan view showing the support device 9 of the ninth embodiment observed from the + Z side.
- FIG. 18B is a cross-sectional view of the support device 9 shown in FIG. 18A taken along the line XVIII-XVIII ′.
- the detailed description is abbreviate
- the support device 9 includes a base member 91.
- the base member 91 includes a first surface 111, a second surface 112, a third surface 113, a fourth surface 114, a fifth surface 115, and a sixth surface 116.
- the fifth surface 115 includes an upper surface 115a and a lower surface 115b.
- the base member 91 has a first through hole 117a and a second through hole 117b. Grooves 118 a and 118 b are formed in the base member 91.
- the base member 91 further includes a seventh surface 119-1.
- the seventh surface 119-1 is a surface parallel to the YZ plane.
- the seventh surface 119-1 is a surface extending from the ⁇ X side outer edge of the lower surface 115b toward the + Z side.
- the seventh surface 119-1 is a surface extending from the outer edge of the upper surface 115a toward the -Z side.
- the seventh surface 119-1 is a surface facing the + X side.
- a first hole 119a-1 and a second hole 119b-1 are formed in the seventh surface 119-1.
- the first hole 119a-1 and the second hole 119b-1 are formed so as to be aligned along the Z axis.
- the first hole 119a-1 is located on the + Z side with respect to the second hole 119b-1.
- the first hole 119a-1 and the second hole 119b-1 are holes into which a protrusion 932b-1 provided in the movable member 93 described later can be fitted.
- the base member 91 further includes an eighth surface 119-2.
- the eighth surface 119-2 is a surface parallel to the YZ plane.
- the eighth surface 119-2 is a surface extending from the outer edge on the + X side of the lower surface 115b toward the + Z side.
- the eighth surface 119-2 is a surface extending from the outer edge of the upper surface 115a toward the ⁇ Z side.
- the eighth surface 119-2 is a surface facing the -X side.
- a first hole 119a-2 and a second hole 119b-2 are formed in the eighth surface 119-2.
- the first hole 119a-2 is located on the same XY plane as the first hole 119a-1.
- the second hole 119b-2 is located on the same XY plane as the second hole 119b-1.
- the first hole 119a-2 and the second hole 119b-2 are formed so as to be aligned along the Z axis.
- the first hole 119a-2 is located on the + Z side with respect to the second hole 119b-2.
- the first hole 119a-2 and the second hole 119b-2 are holes into which a protrusion 932b-2 included in the movable member 93 described later can be fitted.
- foundation member 91 may be the same as other features of the foundation member 11 and the like.
- the support device 9 further includes a plurality of columnar members 92.
- the columnar member 92 is a member that supports a support object such as the biochip 14.
- FIG. 19 is a cross-sectional view showing a cross section taken along the XZ plane of the first columnar member 921 and the second columnar member 922 provided in the columnar member 92.
- the features of the columnar member 92 other than those described below may be the same as the features of the columnar member 12 and the like described above.
- the columnar member 92 includes a first columnar member 921 and a second columnar member 922.
- the first columnar member 921 includes a first upper surface 921a, a welding member 921b, and a first outer surface 921c.
- the features of the first upper surface 921a, the welding member 921b, and the first outer surface 921c other than the features described below are the same as the features of the first upper surface 121a, the welding member 121b, the first outer surface 121c, and the like described above. Also good.
- the first upper surface 921a is a surface parallel to the XY plane.
- the first upper surface 921a is a surface located on the most + Z side among the surfaces constituting the first columnar member 921.
- the first upper surface 921a is a surface facing the + Z side.
- the shape of the outer edge of the first upper surface 921a on the XY plane is a square.
- the welding member 921b is formed on the first upper surface 921a.
- the welding member 921b is a member integrated with the first upper surface 921a.
- the welding member 921b is melted by being irradiated with ultrasonic waves when the first columnar member 921 and the second columnar member 922 are fixed. As a result, the first columnar member 921 and the second columnar member 922 are fixed by the welding member 921b acting as an adhesive.
- the first outer surface 921c is a surface extending from the outer edge of the first upper surface 921a toward the ⁇ Z side.
- the first outer surface 921c is a surface extending from the lower surface 115b toward the + Z side.
- the first outer surface 921c is directed outward.
- the first outer surface 121c is a surface parallel to the Z axis.
- the shape of the outer edge of the first outer surface 921c on the XY plane is a square.
- the second columnar member 922 includes a first upper surface 922a, a first outer surface 922b, and a first lower surface 922c.
- the features of the first upper surface 922a, the first outer surface 922b, and the first lower surface 922c other than the features described below are the same as the features of the first upper surface 122a, the first outer surface 122c, the second lower surface 122g, and the like described above. There may be.
- the first upper surface 922a is a surface located on the most + Z side among the surfaces constituting the second columnar member 922.
- the first upper surface 922a is a surface facing the + Z side.
- the first upper surface 922a is a surface parallel to the XY plane.
- the shape of the outer edge of the first upper surface 922a on the XY plane is a square.
- the first outer surface 922b is a surface extending from the outer edge of the first upper surface 922a toward the -Z side.
- the first outer surface 922b is a surface facing the outer direction.
- the first outer surface 922b is a surface parallel to the Z axis.
- the shape of the outer edge of the first outer surface 922b on the XY plane is a square.
- the first lower surface 922c is a surface extending inward from the outer edge on the ⁇ Z side of the first outer surface 922b.
- the first lower surface 922c is a surface facing the ⁇ Z side.
- the first lower surface 922c is a surface parallel to the XY plane.
- the shape of the outer edge of the first lower surface 922c on the XY plane is a square.
- the first lower surface 922c of the second columnar member 922 can be fitted (or contactable) with the first upper surface 921a of the first columnar member 921 when the first columnar member 921 and the second columnar member 922 are fixed to each other. It is a surface that can be opposed).
- the shape of the outer edge of the first lower surface 922c on the XY plane is the same as the shape of the outer edge of the first upper surface 921a on the XY plane.
- the diameter of the first lower surface 922c on the XY plane is the same as the diameter of the first upper surface 921a on the XY plane (however, a margin that can be fitted or an error caused by fitting accuracy may be considered). is there.
- the support device 9 further includes a movable member 93.
- the movable member 93 is a member that can move along the Z-axis.
- the movable member 93 is a member capable of moving along the Z axis at least a part of a rubber film 94 described later that covers the surface of the movable member 93 by moving along the Z axis.
- the movable member 93 is a member capable of protruding along the Z-axis at least a part of a rubber film 94 described later that covers the surface of the movable member 93 by moving along the Z-axis.
- the movable member 93 is a member that can move the rubber film 94 distributed among the plurality of columnar members 92 along the Z axis by moving along the Z axis.
- FIG. 20A is a plan view of the movable member 93 observed from the + Z side.
- FIG. 20B is a sectional view of the movable member 93 shown in FIG. 20A taken along the line XX (1) -XX (1) ′.
- FIG. 20C is a sectional view of the movable member 93 shown in FIG. 20A taken along the line XX (2) -XX (2) ′.
- FIG. 20D is an enlarged view of the first surface 932a-1 on which the protrusion 932a-1 is formed.
- the features of the columnar member 92 other than those described below may be the same as the features of the columnar member 12 and the like described above.
- the movable member 93 includes a side wall member 931 and a support member 932.
- the side wall member 931 is a member that can be distributed around each columnar member 92.
- the side wall member 931 is a member that can surround each columnar member 92 along the Z axis.
- the side wall member 931 is a surface extending along the Z axis so that each columnar member 92 can be surrounded along the Z axis.
- the side wall member 931 is a member extending in a plate shape from the support member 932 toward the + Z side.
- the side wall member 931 is a member extending toward the + Z side so as to be a wall surrounding each columnar member 92.
- the side wall member 931 is a member that can form a predetermined space together with the first upper surface 922 a of the second columnar member 922.
- the side wall member 931 is a member that can form a predetermined space with the first upper surface 922a of the second columnar member 922 as a bottom.
- the side wall member 931 is configured by walls or plates distributed in a grid pattern, grid pattern or grid pattern on the XY plane so as to surround the 24 columnar members 92. It is a member.
- the side wall member 931 may be referred to as a tubular member in that it can surround each columnar member. Therefore, the characteristics of the side wall member 931 (or the movable member 93) other than the characteristics described below may be the same as the characteristics of the cylindrical member 122 described above.
- the side wall member 931 includes a first inner surface 931a and a first upper surface 931b.
- the first inner surface 931a is a surface surrounding each columnar member 92 along the Z axis.
- the first inner surface 931a is a surface extending along the Z axis.
- the first inner surface 931a is a surface parallel to the Z axis.
- the first inner surface 931a is a surface extending from the support member 932 toward the + Z side.
- the first upper surface 931b is a surface that connects two adjacent first inner surfaces 931a constituting the same wall or plate.
- the first upper surface 931b is a surface facing the + Z side.
- the first upper surface 931b is a curved surface having a shape that swells toward the + Z side.
- the first upper surface 931b is a surface that has been subjected to a rounding process.
- the first upper surface 931b may be a surface having an arbitrary shape.
- the support member 932 is a member that supports the side wall member 931 from the ⁇ Z side.
- the support member 932 includes a first surface 932a-1 and a second surface 932a-2.
- the first surface 932a-1 is a surface located closest to the ⁇ X side among the surfaces constituting the support member 932.
- the first surface 932a-1 is a surface parallel to the Z axis.
- the first surface 932a-1 is a surface facing the -X side.
- the second surface 932a-2 is a surface located on the most + X side among the surfaces constituting the support member 932.
- the second surface 932a-2 is a surface parallel to the Z axis.
- the second surface 932a-2 is a surface facing the + X side.
- a protrusion 932b-1 is formed on the first surface 932a-1.
- the protrusion 932b-1 is a protrusion protruding from the first surface 932a-1 in the ⁇ X side direction.
- the protrusion 932b-1 can be fitted in each of the first hole 119a-1 and the second hole 119b-1 provided in the base member 91.
- the portion of the first surface 932a-1 where the protrusion 932b-1 is formed has a leaf spring structure. Specifically, as shown in FIG. 20D, the portion of the first surface 932a-1 where the protrusion 932b-1 is formed is a slit 932c extending along the Z axis along the Y axis. -1. As a result, the portion of the first surface 932a-1 where the protrusion 932b-1 is formed has elasticity like a leaf spring. Therefore, the protrusion 932b-1 can be easily fitted into the first hole 119a-1 and the second hole 119b-1. Further, the fitting between the protrusion 932b-1 and each of the first hole 119a-1 and the second hole 119b-1 is relatively easily released.
- a protrusion 932b-2 is formed on the second surface 932a-2.
- the protrusion 932b-2 is a protrusion protruding from the second surface 932a-2 toward the + X side direction.
- the protrusion 932b-2 can be fitted into each of the first hole 119a-2 and the second hole 119b-2 provided in the base member 91.
- the portion of the second surface 932a-2 where the protrusion 932b-2 is formed also has a leaf spring structure.
- the support device 9 further includes a rubber film 94.
- the rubber film 94 is made of an elastic material.
- the rubber film 94 is made of a material that does not transmit liquid.
- the rubber film 94 is made of a rubber material. Examples of such materials (rubber materials) include polyisoprene synthetic rubber and latex.
- the rubber film 94 is disposed on the + Z side with respect to the movable member 93.
- the rubber film 94 is disposed so as to cover the movable member 93.
- the rubber film 94 is disposed so as to cover the side wall member 931 constituting the movable member 93.
- the rubber film 94 is arranged so as not to cover the columnar member 92 (further, a support object such as the biochip 14 supported by the columnar member 92).
- the rubber film 94 is disposed such that the columnar member 92 (and further, a support object such as the biochip 14 supported by the columnar member 92) is exposed from the rubber film 94.
- the outer end of the rubber film 94 is fixed to a film fixing part (not shown) formed on the upper surface 115a.
- FIG. 21A is a plan view of the rubber film 94 observed from the + Z side.
- FIG. 21B is a cross-sectional view along the XZ plane showing the rubber film 94 fixed to the columnar member 92 together with the columnar member 92.
- FIG. 21B is a plan view of the rubber film 94 fixed to the columnar member 92 together with the columnar member 92 and observed from the + Z side.
- the rubber film 94 has a rectangular shape in plan view.
- An opening 941 for exposing the columnar member 92 from the rubber film 94 is formed in the rubber film 94.
- the number of openings 941 formed in the rubber film 94 is the same as the number of columnar members 92.
- the shape of the opening 941 is a square shape in plan view.
- the end 941a of the opening 941 is fixed to the columnar member 92.
- the end 941a of the opening 941 is the first when the first columnar member 921 and the second columnar member 922 are fixed. It is sandwiched between the first upper surface 921a of the columnar member 921 and the first lower surface 922c of the second columnar member 922.
- the first columnar member 921 and the second columnar member 922 are fixed while the end portion 941a of the opening 941 is sandwiched, whereby the end portion 941a of the opening 941 is fixed to the columnar member 92.
- FIG. 22A is a cross-sectional view showing a cross section along the XZ plane of the support device 9 in the initial state.
- FIG. 22B is a cross-sectional view showing a cross section along the XZ plane of the support device 9 in the final state. 22 (a) and 22 (b), a specific example of a method of using the support device 9 when the support device 9 supports the biochip 14 will be described.
- the protrusion 932b-1 of the movable member 932 in the initial state, is fitted into the first hole 119a-1 of the base member 91, and A state in which the protrusion 932b-2 of the movable member 932 is fitted in the first hole 119a-2 of the base member 91 is shown.
- the distance D is not less than the predetermined distance D1.
- a space SP9 surrounded by the rubber film 94 covering the side wall member 931 located around each columnar member 92 and the first upper surface 922a is secured.
- the height of the side wall member 931 is the distance D in the initial state. Is appropriately designed to be equal to or greater than the predetermined distance D1.
- a space SP9 surrounded by the rubber film 94 covering the side wall member 931 positioned around each columnar member 92 and the first upper surface 922a is secured.
- An arbitrary holding object can be held in the space SP9.
- the sample LQ is held in the space SP9.
- the rubber film 94 covering the side wall member 931 positioned around each columnar member 92 and the first upper surface 922a constitute a well (or container or tub) that can hold the sample LQ. . Therefore, in the initial state, the support device 9 can function as a so-called well plate. As a result, the reaction of the biochip 14 to the sample LQ is promoted.
- the rubber film 94 is made of a material that does not allow water to pass therethrough.
- the end 941a of the opening 941 of the rubber film 94 is fixed to the columnar member 92 on the ⁇ Z side with respect to the first upper surface 922a. Therefore, the sample LQ held in the space SP9 does not leak through the rubber film 94 itself, through the opening 941 of the rubber film 94, or through the joint surface between the rubber film 94 and the columnar member 92. Almost no. That is, in the ninth embodiment, the water tightness of the space SP9 is suitably ensured.
- the first upper surface 931b of the side wall member 931 pushes the rubber film 94 to the + Z side. Even in this case, since the first upper surface 931b is a curved surface, the tearing of the rubber film 94 is preferably suppressed. Therefore, it can be said that the water-tightness of the space SP9 is suitably secured in that the rubber film 94 is prevented from being broken.
- the movable member 93 is movable toward the ⁇ Z side with reference to the support device 9 in such an initial state.
- the support member 932 may be pulled down toward the ⁇ Z side by a jig (not shown).
- the side wall member 931 extending from the support member 932 is also pulled down toward the ⁇ Z side.
- the movable member 93 moves toward the ⁇ Z side.
- the fitting between the projection 932b-1 and the first hole 119a-1 and the fitting between the projection 932b-2 and the first hole 119a-2 are released. Thereafter, when the movable member 93 moves toward the ⁇ Z side, as shown in FIG. 22B, at a certain point, the projection 932b-1 and the second hole 119b-1 are fitted and the projection 932b-2 and the second hole 119b-2 are fitted.
- the state in which the projection 932b-1 and the second hole 119b-1 are fitted and the projection 932b-2 and the second hole 119b-2 are fitted is defined as a final state. To do.
- the distance D from the first upper surface 922a of the second columnar member 922 to the first upper surface 931b of the side wall member 931 (or the top of the rubber film 94) is equal to or less than the predetermined distance D2.
- the height of the side wall member 931 is the distance D in the final state. Is appropriately designed to be equal to or less than the predetermined distance D2.
- the first upper surface 922a is exposed from the side wall member 931 or the rubber film 94.
- the approach of the objective lens LS to the first upper surface 922a or the biochip 14 is hardly or completely inhibited by the side wall member 931 or the rubber film 94.
- the support device 9 of the ninth embodiment can suitably or appropriately enjoy at least some of the various effects that can be enjoyed by the support device 1 of the first embodiment.
- the columnar member 92, the movable member 93, and the rubber film 94 described with reference to FIGS. 18 to 22 are examples. Therefore, the structure of part of the columnar member 92, the movable member 93, and the rubber film 94 may be modified as appropriate. Hereinafter, an example of modification of a part of the configuration of the columnar member 92, the movable member 93, and the rubber film 94 will be described.
- the base member 91 may not include at least one of the seventh surface 119-1 and the eighth surface 119-2.
- At least a part of the seventh surface 119-1 may be a surface inclined with respect to the YZ plane. At least a part of the seventh surface 119-1 may be a curved surface. The seventh surface 119-1 may not have at least one of the first hole 119a-1 and the second hole 119b-1. The first hole 119a-1 and the second hole 119b-1 may be formed so as not to line up along the Z axis.
- At least a part of the eighth surface 119-2 may be a surface inclined with respect to the YZ plane. At least a part of the eighth surface 119-2 may be a curved surface. On the eighth surface 119-2, at least one of the first hole portion 119a-2 and the second hole portion 119b-2 may not be formed. The first hole 119a-2 and the second hole 119b-2 may be formed so as not to line up along the Z-axis.
- the protrusion 932b-1 does not have to be formed on the first surface 932a-1 of the movable member 93.
- the protrusion 932b-2 may not be formed on the second surface 932a-2 of the movable member 93.
- a portion of the first surface 932a-1 where the protrusion 932b-1 is formed may not have a leaf spring structure.
- the portion of the second surface 932a-2 where the protrusion 932b-2 is formed may not have a leaf spring structure.
- the support device 9 may include an arbitrary film that can hold the object to be held in addition to or instead of the rubber film 94.
- the support device 9 may include an arbitrary film that can secure the water tightness of the space that holds the object to be held in addition to or instead of the rubber film 94.
- the rubber film 94 may be made of a material different from the material having elasticity.
- the rubber film 94 may be made of a material different from the rubber material.
- the rubber film 94 may have a shape different from the rectangular shape in plan view (for example, an arbitrary polygon, circle, or ellipse in plan view).
- the shape of the opening 941 formed in the rubber film 94 may be a shape different from a square shape in plan view (for example, an arbitrary polygon, circle, or ellipse in plan view).
- the end portion 941 a of the opening 941 may be fixed to a member different from the columnar member 92. In addition to or instead of being fixed, the end 941a of the opening 941 is sandwiched between the first upper surface 921a of the first columnar member 921 and the first lower surface 922c of the second columnar member 922.
- the end portion 941a of the opening 941 is sandwiched between the first upper surface 921a of the first columnar member 921 and the first lower surface 922c of the second columnar member 922. It may be fixed to a film fixing part (not shown) formed on an arbitrary surface of the columnar member 922.
- the side wall member 931 may be referred to as a cylindrical member in that it can surround each columnar member. If it does so, also in the support apparatus 1 of 1st Embodiment mentioned above provided with the cylindrical member 13, the rubber film 94 may be comprised so that the cylindrical member 13 may be covered similarly to the support apparatus 9 of 9th Embodiment. . That is, the cylindrical member 13 may be handled as the side wall member 931 in the support device 1 of the first embodiment. The same applies to the support device 2 of the second embodiment to the support device 8 of the eighth embodiment.
- the inspection device SC uses at least one of the support device 2 of the second embodiment to the support device 9 of the ninth embodiment to perform molecular diagnosis. May be performed.
- FIG. 23 is a schematic diagram illustrating an example of the configuration of the inspection apparatus SC of the present embodiment.
- FIG. 24 is a schematic diagram illustrating an example of the configuration of the measurement apparatus MS of the present embodiment.
- the inspection device SC includes a dispensing device DP, a measuring device MS, and a transport device AM.
- the dispensing device DP performs a dispensing process for dispensing the sample LQ to each space SP1 of the support device 1 in an initial state supporting the biochip 14.
- the dispensing device DP may further perform a reaction process that promotes the reaction between the sample LQ and the biochip 14.
- the dispensing device DP may further perform a cleaning / drying process for cleaning and drying the support device 1 after the sample LQ and the biochip 14 have reacted.
- the transport device AM transports the support device 1 (typically, the support device 1 that has been subjected to the cleaning and drying process) from the dispensing device DP to the measuring device MS.
- the measuring device MS performs a measurement process for optically measuring (in other words, detecting or measuring) the reaction of the biochip 14 with respect to the sample LQ.
- the measurement apparatus MS includes, for example, a stage ST and an objective lens LS.
- the support device 1 conveyed from the dispensing device DP is mounted on the stage ST.
- the objective lens LS approaches the biochip 14 until the distance between the biochip 14 and the lens surface of the objective lens LS is equal to or less than the observable distance.
- the stage ST moves along a plane perpendicular to the optical axis of the objective lens LS (for example, the direction of the arrow in FIG. 24).
- the state of the biochip 14 is measured via the objective lens LS.
- the measurement result is output as image information to the measuring device MS or a control device (not shown).
- FIG. 25 is a flowchart showing an example of the flow of an inspection operation (mainly an operation from dispensing a sample LQ to measuring a reaction of the biochip 14) performed by the inspection apparatus SC.
- the dispensing device DP performs a dispensing process for dispensing the sample LQ to each space SP1 of the support device 1 in the initial state supporting the biochip 14 (step S1). ). Since the support device 1 is in the initial state at the time when the dispensing process is performed, the support device 1 can suitably hold the sample LQ using the space SP1. For this reason, the reaction of the biochip 14 with respect to the sample LQ is promoted.
- the dispensing device DP may perform a reaction process that further promotes the reaction between the sample LQ and the biochip 14.
- the dispensing device DP may perform a reaction process in which the support device 1 into which the sample LQ has been dispensed is vibrated or stirred.
- the dispensing device DP uses the jig 15 described above to attach the cylindrical member 13 included in the support device 1 to the ⁇ Push down toward Z (step S2). As a result, the state of the support device 1 transitions from the initial state to the final state.
- the dispensing device DP performs a cleaning and drying process for cleaning and drying the support device 1 (step S3).
- the support device 1 since the support device 1 is in the final state, the biochip 14 is exposed at the time when the cleaning and drying process is performed. Therefore, the dispensing device DP can suitably clean and dry the biochip 14.
- the transport device AM transports the support device 1 (typically, the support device 1 subjected to the cleaning and drying process) from the dispensing device DP to the measuring device MS.
- the measuring apparatus MS performs a measurement process for optically measuring (in other words, detecting or measuring) the reaction of the biochip 14 with respect to the sample LQ (step S4). Since the support device 1 is in the final state at the time when the measurement process is performed, the cylindrical member 13 hardly or completely obstructs the approach of the objective lens LS to the biochip 14. Therefore, the measuring apparatus MS can suitably perform the measurement process.
- step S2 that pushes down the cylindrical member 13 may be performed after the cleaning and drying process is performed.
- the process of pushing down the cylindrical member 13 is performed at an arbitrary time point during the period from when the sample LQ and the biochip 14 sufficiently or correspondingly react until the measurement process by the measurement apparatus MS is performed. May be.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
図1から図9を参照しながら、第1実施形態の支持装置1について説明を進める。以下では、説明の便宜上、第1実施形態の支持装置1の構成、第1実施形態の支持装置1の製造方法、及び、第1実施形態の支持装置1の使用方法について順に説明する。
初めに、図1から図6を参照しながら、第1実施形態の支持装置1の構成について説明を進める。以下では、説明の便宜上、支持装置1の全体構成、支持装置1を構成する各種部材(主として、後述する柱状部材12及び筒状部材13)の構成、及び、支持装置1を構成する各種部材の間の相対的な位置関係について順に説明する。
図1から図3を参照しながら、第1実施形態の支持装置1の全体構成について説明する。図1は、+Z側から観察される第1実施形態の支持装置1を示す平面図である。図2は、+Y側から観察される第1実施形態の支持装置1を示す側面図である。図3は、図1に示す支持装置1のI-I’断面図である。
続いて、図4(a)から図4(d)を参照しながら、第1実施形態の支持装置1が備える第1柱状部材121について更に説明する。図4(a)は、+Z側から観察される第1柱状部材121の平面図である。図4(b)は、図4(a)に示す第1柱状部材121のIV-IV’断面図である。図4(c)は、+Y側から観察される第1柱状部材121の側面図である。図4(d)は、図4(a)に示す第1柱状部材121のIV-IV’断面図のうち溶着部材121b付近を拡大した断面図である。
続いて、図5(a)から図5(d)を参照しながら、第1実施形態の支持装置1が備える第2柱状部材122について更に説明する。図5(a)は、+Z側から観察される第2柱状部材122の平面図である。図5(b)は、図5(a)に示す第2柱状部材122のV-V’断面図である。図5(c)は、+Y側から観察される第2柱状部材122の側面図である。図5(d)は、-Z側から観察される第1柱状部材121の平面図である。
続いて、図6(a)から図6(d)を参照しながら、第1実施形態の支持装置1が備える筒状部材13について更に説明する。図6(a)は、+Z側から観察される筒状部材13の平面図である。図6(b)は、図6(a)に示す筒状部材13のVI-VI’断面図である。図6(c)は、+Y側から観察される筒状部材122の側面図である。図6(d)は、図6(a)に示す筒状部材13のVI-VI’断面図のうち第1内面13b付近を拡大した断面図である。
続いて、図7を参照しながら、第1実施形態の支持装置1を構成する第1柱状部材121と第2柱状部材122と筒状部材13との間の相対的な位置関係に関する構成について説明する。図7は、4つの突起部13eと4つの穴部122dとが嵌合している状態(以降、このような状態を適宜“初期状態”と称する)での、第1柱状部材121、第2柱状部材122及び筒状部材13のXZ平面に沿った断面を示す断面図である。
続いて、図8(a)から図8(d)を参照しながら、第1実施形態の支持装置1の製造方法について説明する。図8(a)から図8(d)は、夫々、第1実施形態の支持装置1を製造する各工程が実行されている際の支持装置1のXZ平面に沿った断面を示す断面図である。
続いて、図9(a)から図9(e)を参照しながら、第1実施形態の支持装置1の使用方法について説明する。図9(a)から図9(e)は、夫々、第1実施形態の支持装置1を使用する際の支持装置1のXZ平面に沿った断面を示す断面図である。
続いて、図11(a)から図11(d)を参照しながら、第2実施形態の支持装置2について説明する。図11(a)から図11(d)は、第2実施形態の支持装置2が備える第1柱状部材121、第2柱状部材222及び筒状部材23のXZ平面に沿った断面を示す断面図である。尚、第2実施形態の支持装置2は、第1実施形態の支持装置1と比較して、主として第2柱状部材222及び筒状部材23の構成が異なる。以下では、第1実施形態の支持装置1の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図12(a)から図12(d)を参照しながら、第3実施形態の支持装置3について説明する。図12(a)から図12(d)は、第3実施形態の支持装置3が備える第1柱状部材321、第2柱状部材121及び筒状部材13のXZ平面に沿った断面を示す断面図である。尚、第3実施形態の支持装置3は、第1実施形態の支持装置1と比較して、主として第1柱状部材321の構成が異なる。以下では、第1実施形態の支持装置1の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第2実施形態の支持装置2が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図13(a)から図13(c)を参照しながら、第4実施形態の支持装置4について説明する。図13(a)から図13(c)は、第4実施形態の支持装置4が備える第1柱状部材321、第2柱状部材422及び筒状部材43のXZ平面に沿った断面を示す断面図である。尚、第4実施形態の支持装置4は、第1実施形態の支持装置1と比較して、主として第1柱状部材321、第2柱状部材422及び筒状部材43の構成が異なる。以下では、第1実施形態の支持装置1の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第3実施形態の支持装置3が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図14(a)から図14(d)を参照しながら、第5実施形態の支持装置5について説明する。図14(a)は、+Z側から観察した第5実施形態の支持装置5が備える第1柱状部材521の平面図である。図14(b)は、図14(a)に示す第1柱状部材521のXIV-XIV’断面図である。図14(c)から図14(d)は、第5実施形態の支持装置5が備える第1柱状部材521、第2柱状部材422及び筒状部材43のXZ平面に沿った断面を示す断面図である。尚、第5実施形態の支持装置5は、第4実施形態の支持装置4と比較して、主として第1柱状部材521の構成が異なる。以下では、第4実施形態の支持装置4の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第4実施形態の支持装置4が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図15(a)から図15(d)を参照しながら、第6実施形態の支持装置6について説明する。図15(a)から図15(d)は、第6実施形態の支持装置6が備える第1柱状部材121、第2柱状部材622及び筒状部材63のXZ平面に沿った断面を示す断面図である。尚、第6実施形態の支持装置6は、第1実施形態の支持装置1と比較して、主として第2柱状部材622及び筒状部材63の構成が異なる。以下では、第1実施形態の支持装置1の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第5実施形態の支持装置5が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図16(a)から図16(c)を参照しながら、第7実施形態の支持装置7について説明する。図16(a)から図16(c)は、第7実施形態の支持装置7が備える第1柱状部材121、第2柱状部材622及び筒状部材73のXZ平面に沿った断面を示す断面図である。尚、第7実施形態の支持装置7は、第6実施形態の支持装置6と比較して、主として筒状部材73の構成が異なる。以下では、第6実施形態の支持装置6の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第6実施形態の支持装置6が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図17(a)から図17(b)を参照しながら、第8実施形態の支持装置8について説明する。図17(a)は、+Z側から観察した第8実施形態の支持装置8が備える筒状部材13の平面図である。図17(b)は、図17(a)に示す筒状部材13のXVII-XVII’断面図である。尚、第8実施形態の支持装置8は、第1実施形態の支持装置1と比較して、主として筒状部材13の構成が異なる。以下では、第1実施形態の支持装置1の構成とは異なる構成に着目して説明を進める。また、第1実施形態の支持装置1から第7実施形態の支持装置7が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図18(a)から図18(b)を参照しながら、第9実施形態の支持装置9について説明する。図18(a)は、+Z側から観察される第9実施形態の支持装置9を示す平面図である。図18(b)は、図18(a)に示す支持装置9のXVIII-XVIII’断面図である。尚、第1実施形態の支持装置1から第8実施形態の支持装置8が備える各種部材と同一の部材については、同一の参照符号を付することでその詳細な説明を省略する。
続いて、図23から図25を参照しながら、上述した第1実施形態の支持装置1を用いて分子診断を行う検査装置SCについて説明する。尚、検査装置SCは、第1実施形態の支持装置1に加えて又は代えて、第2実施形態の支持装置2から第9実施形態の支持装置9の内の少なくとも一つを用いて分子診断を行ってもよい。
初めに、図23から図24を参照しながら、本実施形態の検査装置SCの構成について説明する。図23は、本実施形態の検査装置SCの構成の一例を示す模式図である。図24は、本実施形態の測定装置MSの構成の一例を示す模式図である。
続いて、図25を参照しながら、検査装置SCが行う検査動作(主として、試料を分注してからバイオチップ14の反応を測定するまでの動作)について説明する。図25は、検査装置SCが行う検査動作(主として、試料LQを分注してからバイオチップ14の反応を測定するまでの動作)の流れの一例を示すフローチャートである。
11 基礎部材
12 柱状部材
121 第1柱状部材
122 第2柱状部材
13 筒状部材
Claims (26)
- 柱状の第1部材と、
前記第1部材の外面の少なくとも一部と対向可能な内面を備え、且つ、前記内面によって規定される筒内に前記第1部材の少なくとも一部が挿入されている筒状の第2部材と
を備えており、
前記第1及び第2部材の状態は、第1状態から第2状態へと遷移可能であり、
前記第1状態は、前記第2部材の前記内面の少なくとも一部と前記外面とは異なる前記第1部材の一方側の端面とによって囲まれる所定空間が確保されている状態を含み、
前記第2状態は、前記第1状態における前記第1及び第2部材の位置を基準として、前記第1部材に対して前記第2部材が前記一方側とは逆の他方側に向かって相対的に移動している状態を含む
ことを特徴とする支持装置。 - 前記第1状態は、前記第1部材の前記一方側の端面から前記第2部材の前記一方側の端面までの距離が第1距離となる状態を含み、
前記第2状態は、前記第1部材の前記一方側の端面から前記第2部材の前記一方側の端面までの距離が前記第1距離よりも短い第2距離となる状態を含む
ことを特徴とする請求項1に記載の支持装置。 - 前記第1状態は、前記第2部材の前記一方側の端面が前記第1部材の前記一方側の端面よりも前記一方側に位置している状態を含み、
前記第2状態は、前記第2部材の前記一方側の端面が前記第2部材の前記一方側の端面よりも前記他方側に位置している状態を含む
ことを特徴とする請求項1又は2に記載の支持装置。 - 前記第1部材の前記外面の少なくとも一部と、前記第2部材の前記内面の少なくとも一部とは、前記第1及び第2部材の周方向に渡って嵌合可能であり、
前記第1状態は、前記第1部材の外面の少なくとも一部と前記第2部材の前記内面の少なくとも一部との間の嵌合面よりも前記一方側において前記所定空間が確保されている状態を含む
ことを特徴とする請求項1から3のいずれか一項に記載の支持装置。 - 前記第2部材は、前記第1部材の前記外面の少なくとも一部から受ける応力によって伸びることが可能な弾性を有しており、
前記第2部材が有する弾性に起因して前記第2部材の前記内面の少なくとも一部が前記第1部材の前記外面の少なくとも一部に密着している
ことを特徴とする請求項1から4のいずれか一項に記載の支持装置。 - 前記第2部材は、前記所定空間の水密性を確保可能な水密膜によって覆われている
ことを特徴とする請求項1から5のいずれか一項に記載の支持装置。 - 前記水密膜には、前記第1部材の前記一方側の端面を露出させることが可能な開口が形成されており、
前記開口を規定する前記水密膜の端部は、前記第1部材の前記一方側の端面よりも前記他方側において前記第1部材に固着されている
ことを特徴とする請求項6に記載の支持装置。 - 前記第1及び第2部材の少なくとも一方は、前記第1及び第2部材の状態が前記第1状態となるように前記第1及び第2部材を固定する第1固定部を備える
ことを特徴とする請求項1から7のいずれか一項に記載の支持装置。 - 前記第1固定部は、前記第1部材の前記外面及び前記第2部材の前記内面のうちの少なくとも一方に形成された第1穴部と前記第1部材の前記外面及び前記第2部材の前記内面のうちの少なくとも他方に形成され且つ前記第1穴部に嵌合可能な第1突起部とを含む
ことを特徴とする請求項8に記載の支持装置。 - 前記第1部材の外面は、前記第1穴部又は前記第1突起部が形成される第1外面部分と、前記第1外面部分よりも前記他方側に位置し且つ前記第1外面部分よりも径が小さい第2外面部分とを含む
ことを特徴とする請求項9に記載の支持装置。 - 前記第1穴部又は前記第1突起部は、前記第1部材の前記一方側の端面よりも前記第1部材の前記第2外面部分に近い位置に形成されている
ことを特徴とする請求項10に記載の支持装置。 - 前記第2部材は、前記第1穴部又は前記第1突起部が形成される第1部分と、前記第1部分とは異なる第2部分とを含み、
前記第1部分の少なくとも一部の厚さは、前記第2部分の厚さよりも薄い
ことを特徴とする請求項9から11のいずれか一項に記載の支持装置。 - 前記第2部材の前記内面は、少なくとも前記第1突起部よりも前記一方側において、前記一方側に向かうにつれて前記第2部材の前記内面の径が広がる第1テーパ形状面を含む
ことを特徴とする請求項9から12のいずれか一項に記載の支持装置。 - 前記第1固定部は、前記第1部材の前記外面に形成され且つ前記第1状態にある前記第2部材の前記他方側の端面を前記他方側から支持可能な第2突起部を含む
ことを特徴とする請求項8から13のいずれか一項に記載の支持部 - 前記第1及び第2部材の少なくとも一方は、前記第1及び第2部材の状態が前記第2状態となるように前記第1及び第2部材を固定する第2固定部を備える
ことを特徴とする請求項1から14のいずれか一項に記載の支持装置。 - 前記第1部材の前記外面は、前記他方側に向かうにつれて前記第1部材の前記外面の径が広がる第2テーパ形状面を含み、
前記第2固定部は、前記第2テーパ形状面を含む
ことを特徴とする請求項15に記載の支持装置。 - 前記第1部材は、前記第2部材の前記内面の少なくとも一部から受ける応力によって前記第1部材の前記外面の少なくとも一部の径が小さくなるように撓むことが可能な弾性を有している
ことを特徴とする請求項1から16のいずれか一項に記載の支持装置。 - 前記第1部材の前記外面の少なくとも一部の内側に空隙が形成されている
ことを特徴とする請求項1から17のいずれか一項に記載の支持装置。 - 前記第1部材の前記外面は、前記他方側に向かうにつれて前記第1部材の前記外面の径が小さくなる第3テーパ形状面を含み、
前記第2部材の前記内面は、前記他方側に向かうにつれて前記第2部材の前記内面の径が小さくなる第4テーパ形状面を含む
ことを特徴とする請求項1から18のいずれか一項に記載の支持装置。 - 前記第2部材として、(i)前記第1部材の外面の少なくとも一部に対向可能な前記内面を備える一の前記第2部材と、(ii)前記一の第2部材の外面の少なくとも一部に対向可能な前記内面を備える他の前記第2部材とを備え、
前記一の第2部材の前記外面は、前記他方側に向かうにつれて前記一の第2部材の前記外面の径が小さくなる第5テーパ形状面を含み、
前記第1状態は、前記一の第2部材の前記内面の少なくとも一部と前記第1部材の前記外面の少なくとも一部とが嵌合しており、且つ、前記一の第2部材の前記外面の少なくとも一部と前記他の第2部材の前記内面の少なくとも一部とが嵌合している状態を含み、
前記第2状態は、前記第1状態における前記第1部材並びに前記一の第2部材及び前記他の第2部材の位置を基準として、前記第1部材に対して前記一の第2部材及び前記他の第2部材の双方が前記他方側に向かって相対的に移動している状態を含む
ことを特徴とする請求項19のいずれか一項に記載の支持装置。 - 前記第2部材は、少なくとも前記他方側に向かって移動可能である
ことを特徴とする請求項1から20のいずれか一項に記載の支持装置。 - 複数の前記第1部材と、当該複数の第1部材の前記外面に夫々対向可能な前記内面を備える複数の前記第2部材とを備えている
ことを特徴とする請求項1から21のいずれか一項に記載の支持装置。 - 前記複数の第2部材が一体化されている
ことを特徴とする請求項22に記載の支持装置。 - 前記第1部材の前記一方側の端面は、第1面と、前記第1面の周囲に位置し且つ前記第1面の法線から離れる方向を向くように前記第1面に対して傾斜している第2面とを含む
ことを特徴とする請求項1から23のいずれか一項に記載の支持装置。 - 前記第1部材の前記一方側の端面は、バイオチップを支持可能な支持領域を含む
ことを特徴とする請求項1から24のいずれか一項に記載の支持装置。 - 柱状の第1部材と、前記第1部材の外面の少なくとも一部に対向可能な内面を備え、且つ、前記内面によって規定される筒内に前記第1部材の少なくとも一部が挿入されている筒状の第2部材とを備える支持装置を用いた検査方法であって、
前記第2部材の前記内面の少なくとも一部と前記外面とは異なる前記第1部材の一方側の端面とによって囲まれる所定空間が確保されている状態で、前記所定空間に検査対象試料を注入し、
前記検査対象試料が注入されている間の前記第1及び第2部材の位置を基準として、前記第1部材に対して前記第2部材が前記一方側とは逆の他方側に向かって相対的に移動するように、前記第1及び第2部材の少なくとも一方を移動させ、
前記第1及び第2部材の少なくとも一方を移動させた後に、前記第1部材の一方側の端面に測定装置を近づける
ことを特徴とする検査方法。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016511939A JPWO2015152255A1 (ja) | 2014-03-31 | 2015-03-31 | 支持装置及び検査方法 |
US15/129,606 US20170274382A1 (en) | 2014-03-31 | 2015-03-31 | Supporting device and inspection method |
EP15773954.1A EP3128331A4 (en) | 2014-03-31 | 2015-03-31 | Supporting device and inspection method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014-071244 | 2014-03-31 | ||
JP2014071244 | 2014-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2015152255A1 true WO2015152255A1 (ja) | 2015-10-08 |
Family
ID=54240574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2015/060156 WO2015152255A1 (ja) | 2014-03-31 | 2015-03-31 | 支持装置及び検査方法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20170274382A1 (ja) |
EP (1) | EP3128331A4 (ja) |
JP (2) | JPWO2015152255A1 (ja) |
WO (1) | WO2015152255A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI629104B (zh) * | 2017-09-06 | 2018-07-11 | 諾貝爾生物有限公司 | 處理生化檢體之裝置 |
CN109590036B (zh) * | 2018-12-17 | 2024-04-19 | 苏州汶颢微流控技术股份有限公司 | 一种elisa芯片及其使用方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09285459A (ja) * | 1996-04-23 | 1997-11-04 | Casio Comput Co Ltd | バイオセンサ |
JP2004061470A (ja) * | 2002-07-31 | 2004-02-26 | Yoshino Kogyosho Co Ltd | 自動注出が可能な液体収容容器 |
JP2004340754A (ja) * | 2003-05-15 | 2004-12-02 | Tdk Corp | 分析試料容器用アタッチメント、分析方法および分析装置 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL60645A (en) * | 1980-07-21 | 1984-02-29 | Cais Michael | Method and device for mass transfer and separation through selective barriers |
EP1272768A4 (en) * | 2000-02-23 | 2005-09-07 | Zyomyx Inc | MICROFLUIDIC DEVICES AND ASSOCIATED METHODS |
US20070116613A1 (en) * | 2005-11-23 | 2007-05-24 | Donat Elsener | Sample tube and system for storing and providing nucleic acid samples |
US7790117B2 (en) * | 2008-03-21 | 2010-09-07 | Scientific Plastic Products, Inc. | Filter vial |
TWI406712B (zh) * | 2011-05-18 | 2013-09-01 | Taigen Bioscience Corp | 安全處理生化檢體之裝置 |
EP2623204A1 (en) * | 2012-02-03 | 2013-08-07 | F. Hoffmann-La Roche AG | Sample handling system |
-
2015
- 2015-03-31 WO PCT/JP2015/060156 patent/WO2015152255A1/ja active Application Filing
- 2015-03-31 EP EP15773954.1A patent/EP3128331A4/en not_active Withdrawn
- 2015-03-31 US US15/129,606 patent/US20170274382A1/en not_active Abandoned
- 2015-03-31 JP JP2016511939A patent/JPWO2015152255A1/ja active Pending
-
2018
- 2018-06-13 JP JP2018112886A patent/JP2018138932A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09285459A (ja) * | 1996-04-23 | 1997-11-04 | Casio Comput Co Ltd | バイオセンサ |
JP2004061470A (ja) * | 2002-07-31 | 2004-02-26 | Yoshino Kogyosho Co Ltd | 自動注出が可能な液体収容容器 |
JP2004340754A (ja) * | 2003-05-15 | 2004-12-02 | Tdk Corp | 分析試料容器用アタッチメント、分析方法および分析装置 |
Non-Patent Citations (1)
Title |
---|
See also references of EP3128331A4 * |
Also Published As
Publication number | Publication date |
---|---|
JP2018138932A (ja) | 2018-09-06 |
JPWO2015152255A1 (ja) | 2017-04-13 |
EP3128331A1 (en) | 2017-02-08 |
EP3128331A4 (en) | 2017-08-23 |
US20170274382A1 (en) | 2017-09-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2018138932A (ja) | 支持装置及び検査方法 | |
JP5282273B2 (ja) | マイクロチップ及びマイクロチップの製造方法 | |
JP2014097485A (ja) | 液体取扱装置 | |
US20110014422A1 (en) | Microchip and Method of Manufacturing Same | |
WO2016084455A1 (ja) | 液体センサの組立方法及び液体センサ | |
JP2016217847A (ja) | 液体試料検査具 | |
EP2312322A1 (en) | Microchip | |
JP2014122831A (ja) | マイクロ流路デバイス | |
JP6583345B2 (ja) | 試料保持具、固定部材及び試料固定方法 | |
JP7251265B2 (ja) | 細胞培養器具 | |
US20100310437A1 (en) | Microchip and Method for Manufacturing the Same | |
WO2016084456A1 (ja) | 液体センサ | |
JP5395480B2 (ja) | マイクロチップ及びマイクロチップセット | |
JP6458478B2 (ja) | 採集容器用アダプタ | |
JP2006201367A (ja) | 検鏡プレート | |
JP5206191B2 (ja) | 検査対象受体及び当該検査対象受体を備えた検査装置 | |
KR101309435B1 (ko) | 바이오 칩 | |
JP2005164811A (ja) | レンズ保持構造、対物レンズ、光学顕微鏡および組立方法 | |
JP2007155628A (ja) | 測定装置および光学素子の評価方法 | |
WO2021100519A1 (ja) | 流体取扱装置 | |
US10006926B2 (en) | Specimen inspection apparatus | |
JP5549719B2 (ja) | 検査対象受体 | |
JP5838418B2 (ja) | マイクロリアクタ | |
WO2016152303A1 (ja) | マイクロ流路デバイス、並びに分析装置及び分析方法 | |
JP2008203193A (ja) | マイクロプレートの製造方法及びマイクロプレート |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 15773954 Country of ref document: EP Kind code of ref document: A1 |
|
ENP | Entry into the national phase |
Ref document number: 2016511939 Country of ref document: JP Kind code of ref document: A |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
REEP | Request for entry into the european phase |
Ref document number: 2015773954 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2015773954 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 15129606 Country of ref document: US |