WO2013095042A3 - 이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법 - Google Patents

이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법 Download PDF

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Publication number
WO2013095042A3
WO2013095042A3 PCT/KR2012/011268 KR2012011268W WO2013095042A3 WO 2013095042 A3 WO2013095042 A3 WO 2013095042A3 KR 2012011268 W KR2012011268 W KR 2012011268W WO 2013095042 A3 WO2013095042 A3 WO 2013095042A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
immediate release
imatinib mesylate
tablet composition
granule
Prior art date
Application number
PCT/KR2012/011268
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English (en)
French (fr)
Other versions
WO2013095042A2 (ko
Inventor
양윤희
최하용
박영준
Original Assignee
씨제이제일제당(주)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 씨제이제일제당(주) filed Critical 씨제이제일제당(주)
Publication of WO2013095042A2 publication Critical patent/WO2013095042A2/ko
Publication of WO2013095042A3 publication Critical patent/WO2013095042A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

본 발명은 이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법에 관한 것이며, 보다 상세하게는 이매티닙메실산염 또는 그의 약제학적으로 허용가능한 염을 유효성분으로 하고 결합제로서 수불용성 고분자를 포함하는 과립, 이 과립을 포함하는 만성골수성백혈병 치료를 위한 경구용 속방성 정제 조성물 및 그것의 제조방법에 관한 것이다.
PCT/KR2012/011268 2011-12-23 2012-12-21 이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법 WO2013095042A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0141057 2011-12-23
KR1020110141057A KR101428149B1 (ko) 2011-12-23 2011-12-23 이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법

Publications (2)

Publication Number Publication Date
WO2013095042A2 WO2013095042A2 (ko) 2013-06-27
WO2013095042A3 true WO2013095042A3 (ko) 2013-08-15

Family

ID=48669665

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/011268 WO2013095042A2 (ko) 2011-12-23 2012-12-21 이매티닙메실산염 함유 과립, 이를 포함하는 경구용 속방성 정제 조성물 및 그것의 제조방법

Country Status (2)

Country Link
KR (1) KR101428149B1 (ko)
WO (1) WO2013095042A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019229648A1 (en) * 2018-05-28 2019-12-05 Shivalik Rasayan Limited Oral compositions of imatinib mesylate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100728846B1 (ko) * 2002-04-23 2007-06-14 노파르티스 아게 약물 함유량이 높은 정제
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제
KR20100044286A (ko) * 2005-05-10 2010-04-29 노파르티스 아게 이마티닙 및 방출 지연제를 포함하는 제약 조성물
KR20110007095A (ko) * 2008-03-21 2011-01-21 엘란 파마 인터내셔널 리미티드 이마티니브의 부위-특이적 전달을 위한 조성물 및 사용방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100728846B1 (ko) * 2002-04-23 2007-06-14 노파르티스 아게 약물 함유량이 높은 정제
KR20100044286A (ko) * 2005-05-10 2010-04-29 노파르티스 아게 이마티닙 및 방출 지연제를 포함하는 제약 조성물
KR100812538B1 (ko) * 2006-10-23 2008-03-11 한올제약주식회사 약물 제어방출형 메트포르민-글리메피리드 복합제제
KR20110007095A (ko) * 2008-03-21 2011-01-21 엘란 파마 인터내셔널 리미티드 이마티니브의 부위-특이적 전달을 위한 조성물 및 사용방법

Also Published As

Publication number Publication date
WO2013095042A2 (ko) 2013-06-27
KR20130073288A (ko) 2013-07-03
KR101428149B1 (ko) 2014-08-08

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