WO2012169819A3 - 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법 - Google Patents

2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법 Download PDF

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WO2012169819A3
WO2012169819A3 PCT/KR2012/004523 KR2012004523W WO2012169819A3 WO 2012169819 A3 WO2012169819 A3 WO 2012169819A3 KR 2012004523 W KR2012004523 W KR 2012004523W WO 2012169819 A3 WO2012169819 A3 WO 2012169819A3
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hydroxybutyrate
monomer
polyhydroxyalkanoate containing
producing
producing polyhydroxyalkanoate
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PCT/KR2012/004523
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English (en)
French (fr)
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WO2012169819A2 (ko
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이상엽
박시재
이승환
송봉근
이태우
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한국과학기술원
한국화학연구원
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Publication of WO2012169819A2 publication Critical patent/WO2012169819A2/ko
Publication of WO2012169819A3 publication Critical patent/WO2012169819A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

본 발명은 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법에 관한 것으로, 더욱 자세하게는, 2-하이드록시부티레이트를 함유하는 폴리하이드록시알카노에이트를 대사공학을 이용한 재조합 균주로부터 제조하는 방법에 관한 것이다. 본 발명은 생분해성 신규 폴리머인 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트를 제조할 수 있는 재조합 미생물 및 상기 재조합 미생물을 배양하는 것을 특징으로 하는 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법을 제공하는 효과가 있다.
PCT/KR2012/004523 2011-06-08 2012-06-08 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법 WO2012169819A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110055113A KR101273599B1 (ko) 2011-06-08 2011-06-08 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법
KR10-2011-0055113 2011-06-08

Publications (2)

Publication Number Publication Date
WO2012169819A2 WO2012169819A2 (ko) 2012-12-13
WO2012169819A3 true WO2012169819A3 (ko) 2013-03-07

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Application Number Title Priority Date Filing Date
PCT/KR2012/004523 WO2012169819A2 (ko) 2011-06-08 2012-06-08 2-하이드록시부티레이트를 모노머로 함유하고 있는 폴리하이드록시알카노에이트의 제조방법

Country Status (2)

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KR (1) KR101273599B1 (ko)
WO (1) WO2012169819A2 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230183418A1 (en) * 2016-03-28 2023-06-15 Lg Chem,Ltd Liquid biopolymer, use thereof, and preparation method
KR102036828B1 (ko) 2017-02-28 2019-10-25 한국과학기술원 2-하이드록시이소카프로에이트-CoA 전이효소를 이용한 폴리하이드록시알카노에이트의 제조방법
WO2018159965A1 (ko) * 2017-02-28 2018-09-07 한국과학기술원 2-하이드록시이소카프로에이트-CoA 전이효소를 이용한 폴리하이드록시알카노에이트의 제조방법
KR102361618B1 (ko) * 2018-01-08 2022-02-09 주식회사 엘지화학 2-하이드록시부티레이트 및 3-하이드록시부티레이트의 공중합체 및 이의 제조방법
KR102497785B1 (ko) * 2018-01-08 2023-02-07 주식회사 엘지화학 2-하이드록시부티레이트 및 락테이트의 공중합체 제조를 위한 재조합 균주 및 방법
KR20190090602A (ko) * 2018-01-25 2019-08-02 주식회사 엘지화학 2-하이드록시부티레이트, 2-하이드록시이소발레레이트 및 락테이트의 삼중합체 제조를 위한 재조합 균주 및 방법
CN114561333B (zh) * 2022-02-23 2023-08-25 山东第一医科大学(山东省医学科学院) 一种转化支链氨基酸的工程菌及在制备治疗枫糖尿症产品中的应用
CN115851510B (zh) * 2022-10-13 2023-09-12 深圳中科翎碳生物科技有限公司 盐单胞菌及其在联产四氢嘧啶和聚羟基脂肪酸酯的应用

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
HOZUI, F. ET AL., APPL. MICROBIOL. BIOTECHNOL., vol. 85, 2010, pages 949 - 954 *
MATSUMOTO, K. ET AL., BIOMACROMOLECULES, vol. 6, 2005, pages 99 - 104 *
MATSUMOTO, K. ET AL., BIOMACROMOLECULES, vol. 7, 2006, pages 2436 - 2442 *
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KR101273599B1 (ko) 2013-06-11
KR20120136099A (ko) 2012-12-18
WO2012169819A2 (ko) 2012-12-13

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