WO2012150537A3 - Nuevas formas sólidas de antibióticos - Google Patents

Nuevas formas sólidas de antibióticos Download PDF

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Publication number
WO2012150537A3
WO2012150537A3 PCT/IB2012/052139 IB2012052139W WO2012150537A3 WO 2012150537 A3 WO2012150537 A3 WO 2012150537A3 IB 2012052139 W IB2012052139 W IB 2012052139W WO 2012150537 A3 WO2012150537 A3 WO 2012150537A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid forms
novel solid
antibiotics
hydrates
cocrystals
Prior art date
Application number
PCT/IB2012/052139
Other languages
English (en)
French (fr)
Other versions
WO2012150537A2 (es
Inventor
Hugo MORALES ROJAS
Jorge Guillermo DOMÍNGUEZ CHÁVEZ
Dea HERRERA RUIZ
Herbert HÖPFL
Juan Manuel MARTÍNEZ ALEJO
Juan Pablo SENOSIAIN PELÁEZ
Original Assignee
Laboratorios Senosiain S.A. De C.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Senosiain S.A. De C.V. filed Critical Laboratorios Senosiain S.A. De C.V.
Priority to CA2834818A priority Critical patent/CA2834818A1/en
Priority to US14/115,335 priority patent/US9290492B2/en
Publication of WO2012150537A2 publication Critical patent/WO2012150537A2/es
Publication of WO2012150537A3 publication Critical patent/WO2012150537A3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Abstract

La presente invención se refiere a nuevas formas sólidas de fluoroquinolonas, en particular a cocristales complejos y a los solvatos, hidratos y polimorfos de los mismos. Estas sustancias son útiles para preparar una composición farmacéutica que contiene al mismo como ingrediente activo útil como antibiótico. Dichos compuestos presentan una estabilidad de almacenamiento constante y superior a sales e hidratos del mismo.
PCT/IB2012/052139 2011-05-04 2012-04-27 Nuevas formas sólidas de antibióticos WO2012150537A2 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2834818A CA2834818A1 (en) 2011-05-04 2012-04-27 Novel solid forms of antibiotics
US14/115,335 US9290492B2 (en) 2011-05-04 2012-04-27 Solid forms of antibiotics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXMX/A/2011/004759 2011-05-04
MX2011004759A MX2011004759A (es) 2011-05-04 2011-05-04 Nuevas formas solidas de antibioticos.

Publications (2)

Publication Number Publication Date
WO2012150537A2 WO2012150537A2 (es) 2012-11-08
WO2012150537A3 true WO2012150537A3 (es) 2013-01-10

Family

ID=47108089

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/052139 WO2012150537A2 (es) 2011-05-04 2012-04-27 Nuevas formas sólidas de antibióticos

Country Status (4)

Country Link
US (1) US9290492B2 (es)
CA (1) CA2834818A1 (es)
MX (1) MX2011004759A (es)
WO (1) WO2012150537A2 (es)

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* Cited by examiner, † Cited by third party
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CN110354132A (zh) 2012-06-04 2019-10-22 药品循环有限责任公司 布鲁顿酪氨酸激酶抑制剂的晶形
CN106573002A (zh) 2014-08-07 2017-04-19 药品循环有限责任公司 布鲁顿氏酪氨酸激酶抑制剂的新型制剂
CN104447537B (zh) * 2014-11-17 2016-08-24 河南大学 一种含乙基喹啉环的3,3′-亚甲基-双氟喹诺酮衍生物及其制备方法和应用
CN104530091B (zh) * 2014-12-23 2017-01-11 河南大学 一种手性3,3′-亚甲基-双噁嗪(噻嗪)并氟喹诺酮衍生物及其制备方法和应用
TW202315634A (zh) 2015-03-03 2023-04-16 美商製藥公司 布魯東氏（ｂｒｕｔｏｎ’ｓ）酪胺酸激酶抑制劑之醫藥調配物
MA41828A (fr) * 2015-03-27 2018-01-30 Pharmacyclics Llc Co-cristaux d'un inhibiteur de la tyrosine kinase de bruton
CN108653286B (zh) * 2017-04-01 2020-01-10 北京福元医药股份有限公司 一种莫西沙星药物制剂
CN113194932A (zh) 2018-12-18 2021-07-30 东丽株式会社 氧化铈的纳米粒子、核酸的分解方法、多肽的分解方法、氧化铈的纳米粒子的制造方法、氧化剂、抗氧化剂、抗霉剂及抗病毒剂
CN113264878B (zh) * 2019-11-11 2022-05-27 山东畜牧兽医职业学院 一种用于畜牧业治疗耐药性微生物菌的化合物的制备方法
CN113233976B (zh) * 2021-05-08 2021-11-16 广州萃普生物科技有限公司 一种没食子酸和氨基乙酸共晶及含有该共晶的美白膏霜

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2127036A1 (es) * 1994-03-21 1999-04-01 Ind Quimica Agropecuaria S A Aducto de norfloxacina soluble en agua.
WO2009136408A1 (en) * 2008-04-09 2009-11-12 Institute Of Life Sciences Synergistic pharmaceutical cocrystals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72483C2 (en) 1998-11-10 2005-03-15 Moxifloxacin-containing pharmaceutical preparation and method for its manufacture
ES2332367T5 (es) 2003-04-09 2013-12-17 Dr. Reddy's Laboratories Ltd. Forma cristalina III de clorhidrato de moxifloxacina anhidro y su procedimiento de preparación
US20070287194A1 (en) 2004-03-12 2007-12-13 S.S.C.I., Inc Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound
IT1398952B1 (it) 2010-03-19 2013-03-28 F S I Fabbrica Italiana Sint Processo di preparazione della moxifloxacina e suoi sali

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2127036A1 (es) * 1994-03-21 1999-04-01 Ind Quimica Agropecuaria S A Aducto de norfloxacina soluble en agua.
WO2009136408A1 (en) * 2008-04-09 2009-11-12 Institute Of Life Sciences Synergistic pharmaceutical cocrystals

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S BASAVOJU ET AL.: "Pharmaceutical cocrystal and salts of norfloxacin", CRYSTAL GROWTH & DESIGN 2006, vol. 6, no. 12, 2006, pages 2699 - 2708 *

Also Published As

Publication number Publication date
MX2011004759A (es) 2012-11-21
US20140088116A1 (en) 2014-03-27
WO2012150537A2 (es) 2012-11-08
CA2834818A1 (en) 2012-11-08
US9290492B2 (en) 2016-03-22

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