WO2012045019A9 - Déficit en gène brca et méthodes d'utilisation associées - Google Patents

Déficit en gène brca et méthodes d'utilisation associées Download PDF

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Publication number
WO2012045019A9
WO2012045019A9 PCT/US2011/054369 US2011054369W WO2012045019A9 WO 2012045019 A9 WO2012045019 A9 WO 2012045019A9 US 2011054369 W US2011054369 W US 2011054369W WO 2012045019 A9 WO2012045019 A9 WO 2012045019A9
Authority
WO
WIPO (PCT)
Prior art keywords
methods
brca deficiency
brca
deficiency
Prior art date
Application number
PCT/US2011/054369
Other languages
English (en)
Other versions
WO2012045019A2 (fr
Inventor
Kirsten Timms
Darl Flake
Jennifer Potter
Jerry Lanchbury
Original Assignee
Myriad Genetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myriad Genetics, Inc. filed Critical Myriad Genetics, Inc.
Priority to CA2813257A priority Critical patent/CA2813257A1/fr
Publication of WO2012045019A2 publication Critical patent/WO2012045019A2/fr
Publication of WO2012045019A9 publication Critical patent/WO2012045019A9/fr
Priority to US13/852,129 priority patent/US20140024028A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
PCT/US2011/054369 2010-10-01 2011-09-30 Déficit en gène brca et méthodes d'utilisation associées WO2012045019A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2813257A CA2813257A1 (fr) 2010-10-01 2011-09-30 Deficit en gene brca et methodes d'utilisation associees
US13/852,129 US20140024028A1 (en) 2011-09-30 2013-03-28 Brca deficiency and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38869210P 2010-10-01 2010-10-01
US61/388,692 2010-10-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/852,129 Continuation US20140024028A1 (en) 2011-09-30 2013-03-28 Brca deficiency and methods of use

Publications (2)

Publication Number Publication Date
WO2012045019A2 WO2012045019A2 (fr) 2012-04-05
WO2012045019A9 true WO2012045019A9 (fr) 2012-07-19

Family

ID=45893782

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/054369 WO2012045019A2 (fr) 2010-10-01 2011-09-30 Déficit en gène brca et méthodes d'utilisation associées

Country Status (2)

Country Link
CA (1) CA2813257A1 (fr)
WO (1) WO2012045019A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2669682B1 (fr) * 2012-05-31 2017-04-19 Heinrich-Heine-Universität Düsseldorf Nouveaux biomarqueurs pronostiques et prédictifs (marqueurs tumoraux) pour le cancer du sein chez l'homme
CN105793437B (zh) * 2013-09-23 2020-12-15 芝加哥大学 关于dna损伤制剂用于癌症治疗的方法和组合物
US20170058351A1 (en) * 2013-11-28 2017-03-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Methods for Molecular Classification of BRCA-Like Breast and/or Ovarian Cancer

Also Published As

Publication number Publication date
CA2813257A1 (fr) 2012-04-05
WO2012045019A2 (fr) 2012-04-05

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