WO2012045019A9 - Brca deficiency and methods of use - Google Patents

Brca deficiency and methods of use Download PDF

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Publication number
WO2012045019A9
WO2012045019A9 PCT/US2011/054369 US2011054369W WO2012045019A9 WO 2012045019 A9 WO2012045019 A9 WO 2012045019A9 US 2011054369 W US2011054369 W US 2011054369W WO 2012045019 A9 WO2012045019 A9 WO 2012045019A9
Authority
WO
WIPO (PCT)
Prior art keywords
methods
brca deficiency
brca
deficiency
Prior art date
Application number
PCT/US2011/054369
Other languages
French (fr)
Other versions
WO2012045019A2 (en
Inventor
Kirsten Timms
Darl Flake
Jennifer Potter
Jerry Lanchbury
Original Assignee
Myriad Genetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myriad Genetics, Inc. filed Critical Myriad Genetics, Inc.
Priority to CA2813257A priority Critical patent/CA2813257A1/en
Publication of WO2012045019A2 publication Critical patent/WO2012045019A2/en
Publication of WO2012045019A9 publication Critical patent/WO2012045019A9/en
Priority to US13/852,129 priority patent/US20140024028A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
PCT/US2011/054369 2010-10-01 2011-09-30 Brca deficiency and methods of use WO2012045019A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2813257A CA2813257A1 (en) 2010-10-01 2011-09-30 Brca deficiency and methods of use
US13/852,129 US20140024028A1 (en) 2011-09-30 2013-03-28 Brca deficiency and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38869210P 2010-10-01 2010-10-01
US61/388,692 2010-10-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/852,129 Continuation US20140024028A1 (en) 2011-09-30 2013-03-28 Brca deficiency and methods of use

Publications (2)

Publication Number Publication Date
WO2012045019A2 WO2012045019A2 (en) 2012-04-05
WO2012045019A9 true WO2012045019A9 (en) 2012-07-19

Family

ID=45893782

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/054369 WO2012045019A2 (en) 2010-10-01 2011-09-30 Brca deficiency and methods of use

Country Status (2)

Country Link
CA (1) CA2813257A1 (en)
WO (1) WO2012045019A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2669682B1 (en) * 2012-05-31 2017-04-19 Heinrich-Heine-Universität Düsseldorf Novel prognostic and predictive biomarkers (tumor markers) for human breast cancer
CN105793437B (en) * 2013-09-23 2020-12-15 芝加哥大学 Methods and compositions relating to DNA damaging agents for cancer treatment
US20170058351A1 (en) * 2013-11-28 2017-03-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Methods for Molecular Classification of BRCA-Like Breast and/or Ovarian Cancer

Also Published As

Publication number Publication date
WO2012045019A2 (en) 2012-04-05
CA2813257A1 (en) 2012-04-05

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