WO2012034871A3 - Verfahren zum herstellen von wirkstoff-beads - Google Patents
Verfahren zum herstellen von wirkstoff-beads Download PDFInfo
- Publication number
- WO2012034871A3 WO2012034871A3 PCT/EP2011/065186 EP2011065186W WO2012034871A3 WO 2012034871 A3 WO2012034871 A3 WO 2012034871A3 EP 2011065186 W EP2011065186 W EP 2011065186W WO 2012034871 A3 WO2012034871 A3 WO 2012034871A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bead
- active ingredient
- producing
- gravity
- vacuum
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011800441102A CN103209689A (zh) | 2010-09-14 | 2011-09-02 | 用于制造活性成分珠粒料的方法 |
EP11757229.7A EP2616049A2 (de) | 2010-09-14 | 2011-09-02 | Verfahren zum herstellen von wirkstoff-beads |
US13/822,697 US20130277872A1 (en) | 2010-09-14 | 2011-09-02 | Process for the production of active substance beads |
JP2013528594A JP2013537207A (ja) | 2010-09-14 | 2011-09-02 | 活性物質ビーズの製造方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102010040687A DE102010040687A1 (de) | 2010-09-14 | 2010-09-14 | Verfahren zum Herstellen von Wirkstoff-Beads |
DE102010040687.2 | 2010-09-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012034871A2 WO2012034871A2 (de) | 2012-03-22 |
WO2012034871A3 true WO2012034871A3 (de) | 2012-09-07 |
Family
ID=44651711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2011/065186 WO2012034871A2 (de) | 2010-09-14 | 2011-09-02 | Verfahren zum herstellen von wirkstoff-beads |
Country Status (6)
Country | Link |
---|---|
US (1) | US20130277872A1 (de) |
EP (1) | EP2616049A2 (de) |
JP (1) | JP2013537207A (de) |
CN (1) | CN103209689A (de) |
DE (1) | DE102010040687A1 (de) |
WO (1) | WO2012034871A2 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ624195A (en) | 2012-01-31 | 2015-07-31 | Rogosin Inst | Improved method for manufacture of macrobeads |
US10697972B2 (en) | 2016-01-12 | 2020-06-30 | Bioatla, Llc | Diagnostics using conditionally active antibodies |
EP3403098B1 (de) | 2016-01-12 | 2021-09-22 | BioAtla, Inc. | Diagnostika mit bedingt aktiven antikörpern |
DE102017106867B4 (de) | 2017-03-30 | 2021-12-02 | Hamilton Bonaduz Ag | Verfahren zur Herstellung einer Portionseinheit |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5185269A (en) * | 1990-02-13 | 1993-02-09 | Source Scientific Systems, Inc. | Immunobead aspirator and method of use |
USRE38027E1 (en) * | 1994-01-13 | 2003-03-11 | The Rogosin Institute | Preparation of agarose coated, solid agarose-collagen beads containing secretory cells |
US7297331B2 (en) * | 1996-04-03 | 2007-11-20 | The Rogosin Institute | Beads containing restricted cancer cells producing material suppressing cancer cell proliferation |
WO2010099893A2 (de) * | 2009-03-06 | 2010-09-10 | Wolfgang Folger | Vorrichtungen und verfahren zur herstellung von eisperlen aus einem wässrigen gemisch |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4200613A (en) * | 1977-06-03 | 1980-04-29 | Ramco Laboratories Inc. | Radioimmunoassay apparatus |
FI86777C (fi) * | 1990-12-31 | 1992-10-12 | Medix Biochemica Ab Oy | Foerfarande foer diagnosticering av bristningen av fosterhinnorna samt reagensfoerpackning foer anvaendning daervid |
CA2121129A1 (en) * | 1991-10-29 | 1993-05-13 | Patrick Soon-Shiong | Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release |
US5286495A (en) * | 1992-05-11 | 1994-02-15 | University Of Florida | Process for microencapsulating cells |
USRE39542E1 (en) * | 1994-01-13 | 2007-04-03 | The Rogosin Institute | Preparation of agarose coated, solid agarose-collagen beads containing secretory cells |
US5662840A (en) * | 1994-06-10 | 1997-09-02 | Fmc Corporation | Process for making gel microbeads |
US6558665B1 (en) * | 1999-05-18 | 2003-05-06 | Arch Development Corporation | Encapsulating particles with coatings that conform to size and shape of the particles |
DE19941661B4 (de) * | 1999-09-01 | 2004-06-17 | Graffinity Pharmaceuticals Ag | Vorrichtung und Verfahren zum Aufnehmen und Plazieren |
DE10237125A1 (de) * | 2002-08-13 | 2004-03-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Kryokonservierung mit einem gas- oder dampfförmigen Kühlmedium |
US20050147595A1 (en) * | 2003-09-29 | 2005-07-07 | Dagmar Meissner | Bead embedded cells |
JP4427411B2 (ja) * | 2004-07-28 | 2010-03-10 | 日立ソフトウエアエンジニアリング株式会社 | ビーズ配列装置及びビーズ配列方法 |
DE102005018949A1 (de) * | 2005-04-18 | 2006-10-19 | Ami-Agrolinz Melamine International Gmbh | Harnstoffpartikel, Verfahren zu dessen Herstellung und dessen Verwendung |
JP4520359B2 (ja) * | 2005-05-13 | 2010-08-04 | 日立ソフトウエアエンジニアリング株式会社 | 粒子捕捉装置、並びに粒子配列方法及び粒子配列装置 |
SG131015A1 (en) * | 2005-09-15 | 2007-04-26 | Millipore Corp | Method and apparatus for making porous agarose beads |
WO2007144894A1 (en) * | 2006-06-15 | 2007-12-21 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Hydrocolloid carrier beads with inert filler material |
-
2010
- 2010-09-14 DE DE102010040687A patent/DE102010040687A1/de not_active Withdrawn
-
2011
- 2011-09-02 EP EP11757229.7A patent/EP2616049A2/de not_active Withdrawn
- 2011-09-02 WO PCT/EP2011/065186 patent/WO2012034871A2/de active Application Filing
- 2011-09-02 US US13/822,697 patent/US20130277872A1/en not_active Abandoned
- 2011-09-02 CN CN2011800441102A patent/CN103209689A/zh active Pending
- 2011-09-02 JP JP2013528594A patent/JP2013537207A/ja not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5185269A (en) * | 1990-02-13 | 1993-02-09 | Source Scientific Systems, Inc. | Immunobead aspirator and method of use |
USRE38027E1 (en) * | 1994-01-13 | 2003-03-11 | The Rogosin Institute | Preparation of agarose coated, solid agarose-collagen beads containing secretory cells |
US7297331B2 (en) * | 1996-04-03 | 2007-11-20 | The Rogosin Institute | Beads containing restricted cancer cells producing material suppressing cancer cell proliferation |
WO2010099893A2 (de) * | 2009-03-06 | 2010-09-10 | Wolfgang Folger | Vorrichtungen und verfahren zur herstellung von eisperlen aus einem wässrigen gemisch |
Non-Patent Citations (1)
Title |
---|
ANONYMOUS: "www.SPÄTZLE.de - Grundrezept", 1 January 2007 (2007-01-01), pages 1 - 3, XP002676399, Retrieved from the Internet <URL:http://www.spaetzle.de/prt/prt_schaben.html> [retrieved on 20120523] * |
Also Published As
Publication number | Publication date |
---|---|
EP2616049A2 (de) | 2013-07-24 |
DE102010040687A1 (de) | 2012-03-15 |
JP2013537207A (ja) | 2013-09-30 |
CN103209689A (zh) | 2013-07-17 |
US20130277872A1 (en) | 2013-10-24 |
WO2012034871A2 (de) | 2012-03-22 |
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