WO2011047789A9 - Bioabbaubares hydrogel - Google Patents

Bioabbaubares hydrogel Download PDF

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Publication number
WO2011047789A9
WO2011047789A9 PCT/EP2010/006125 EP2010006125W WO2011047789A9 WO 2011047789 A9 WO2011047789 A9 WO 2011047789A9 EP 2010006125 W EP2010006125 W EP 2010006125W WO 2011047789 A9 WO2011047789 A9 WO 2011047789A9
Authority
WO
WIPO (PCT)
Prior art keywords
hydrogel
biodegradable hydrogel
polyurethane
basis
producing
Prior art date
Application number
PCT/EP2010/006125
Other languages
English (en)
French (fr)
Other versions
WO2011047789A1 (de
WO2011047789A8 (de
Inventor
Heike Heckroth
Christoph Eggert
Harmut Nefzger
Jörg Hofmann
Edward Browne
Klaus Lorenz
Original Assignee
Bayer Materialscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Materialscience Ag filed Critical Bayer Materialscience Ag
Priority to IN3446DEN2012 priority Critical patent/IN2012DN03446A/en
Priority to CN2010800471620A priority patent/CN102573947A/zh
Priority to BR112012009266A priority patent/BR112012009266A2/pt
Priority to EP10765758A priority patent/EP2490728A1/de
Priority to AU2010310208A priority patent/AU2010310208A1/en
Priority to CA2780919A priority patent/CA2780919A1/en
Priority to JP2012534567A priority patent/JP2013508482A/ja
Priority to US13/502,397 priority patent/US20120244107A1/en
Publication of WO2011047789A1 publication Critical patent/WO2011047789A1/de
Publication of WO2011047789A9 publication Critical patent/WO2011047789A9/de
Publication of WO2011047789A8 publication Critical patent/WO2011047789A8/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4866—Polyethers having a low unsaturation value
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2210/00—Compositions for preparing hydrogels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicinal Preparation (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Hydrogel auf Basis von Polyurethan oder Polyurethanharnstoff, das in der Polymerkette hydrolysierbare funktionelle Gruppen aufweist, ein Verfahren zur Herstellung des Hydrogels sowie die Verwendung des Hydrogels als Adhäsionsbarrieren.
PCT/EP2010/006125 2009-10-21 2010-10-07 Bioabbaubares hydrogel WO2011047789A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IN3446DEN2012 IN2012DN03446A (de) 2009-10-21 2010-10-07
CN2010800471620A CN102573947A (zh) 2009-10-21 2010-10-07 可生物降解的水凝胶
BR112012009266A BR112012009266A2 (pt) 2009-10-21 2010-10-07 hidrogel biodegradável
EP10765758A EP2490728A1 (de) 2009-10-21 2010-10-07 Bioabbaubares hydrogel
AU2010310208A AU2010310208A1 (en) 2009-10-21 2010-10-07 Biodegradable hydrogel
CA2780919A CA2780919A1 (en) 2009-10-21 2010-10-07 Biodegradable hydrogel
JP2012534567A JP2013508482A (ja) 2009-10-21 2010-10-07 生分解性ヒドロゲル
US13/502,397 US20120244107A1 (en) 2009-10-21 2010-10-07 Biodegradable hydrogel

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09013258 2009-10-21
EP09013258.0 2009-10-21

Publications (3)

Publication Number Publication Date
WO2011047789A1 WO2011047789A1 (de) 2011-04-28
WO2011047789A9 true WO2011047789A9 (de) 2011-07-21
WO2011047789A8 WO2011047789A8 (de) 2012-05-03

Family

ID=41723105

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/006125 WO2011047789A1 (de) 2009-10-21 2010-10-07 Bioabbaubares hydrogel

Country Status (10)

Country Link
US (1) US20120244107A1 (de)
EP (1) EP2490728A1 (de)
JP (1) JP2013508482A (de)
KR (1) KR20120098638A (de)
CN (1) CN102573947A (de)
AU (1) AU2010310208A1 (de)
BR (1) BR112012009266A2 (de)
CA (1) CA2780919A1 (de)
IN (1) IN2012DN03446A (de)
WO (1) WO2011047789A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012107385A1 (de) * 2011-02-09 2012-08-16 Bayer Materialscience Ag Bioabbaubare prepolymere
ES2846300T3 (es) * 2011-12-20 2021-07-28 Adhesys Medical Gmbh Prepolímero con funcionalidad isocianato para un adhesivo de tejido biodegradable
WO2013112381A2 (en) * 2012-01-24 2013-08-01 Bvw Holding Ag New class of anti-adhesion hydrogels with healing aspects
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
CN103992458A (zh) * 2014-06-11 2014-08-20 苏州大学 一种超高强度的聚氨酯脲超分子水凝胶及其制备方法
CN104861176B (zh) * 2015-04-14 2018-08-24 青岛中科润唐新材料科技有限公司 一种可降解聚氨酯水凝胶的制备方法
CN105153437B (zh) * 2015-08-18 2017-11-28 九江学院 一种超线形可降解聚合物水凝胶及其制备方法
US11980700B2 (en) 2017-03-08 2024-05-14 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
KR102120962B1 (ko) * 2017-12-27 2020-06-10 주식회사 티앤엘 개선된 점착성을 가진 하이드로겔 드레싱
KR20220090685A (ko) 2020-12-23 2022-06-30 김진태 롤러형 마사지 장치

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770548A1 (de) 1967-06-02 1972-02-10 Gen Tire & Rubber Co Polyester und ihre Herstellung
US3939123A (en) * 1974-06-18 1976-02-17 Union Carbide Corporation Lightly cross-linked polyurethane hydrogels based on poly(alkylene ether) polyols
JP3097854B2 (ja) 1989-05-12 2000-10-10 旭硝子株式会社 ポリウレタン類の製造方法
US5032671A (en) 1990-09-04 1991-07-16 Arco Chemical Technology, Inc. Preparation of lactone polymers using double metal cyanide catalysts
US5470813A (en) 1993-11-23 1995-11-28 Arco Chemical Technology, L.P. Double metal cyanide complex catalysts
US5712216A (en) 1995-05-15 1998-01-27 Arco Chemical Technology, L.P. Highly active double metal cyanide complex catalysts
US5482908A (en) 1994-09-08 1996-01-09 Arco Chemical Technology, L.P. Highly active double metal cyanide catalysts
US5545601A (en) 1995-08-22 1996-08-13 Arco Chemical Technology, L.P. Polyether-containing double metal cyanide catalysts
US5627120A (en) 1996-04-19 1997-05-06 Arco Chemical Technology, L.P. Highly active double metal cyanide catalysts
US5714428A (en) 1996-10-16 1998-02-03 Arco Chemical Technology, L.P. Double metal cyanide catalysts containing functionalized polymers
DE19905611A1 (de) 1999-02-11 2000-08-17 Bayer Ag Doppelmetallcyanid-Katalysatoren für die Herstellung von Polyetherpolyolen
CN1146613C (zh) * 1999-09-10 2004-04-21 三井化学株式会社 可降解的聚氨酯树脂
TW200604249A (en) * 2004-03-24 2006-02-01 Commw Scient Ind Res Org Biodegradable polyurethane and polyurethane ureas
EP1771490B1 (de) * 2004-07-26 2019-01-02 Synthes GmbH Biokompatible, bioabbaubare polyurethan werkstoffe mit kontrolliertem hydrophob zu hydrophil verhältnis
DE102006050793A1 (de) 2006-10-27 2008-04-30 Bayer Materialscience Ag Neuartige Hydrogele auf Basis aliphatischer NCO-Prepolymere
US8436064B2 (en) * 2007-09-11 2013-05-07 Momentive Performance Materials Inc. Open-cell polyurethane foam and process for its manufacture
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.

Also Published As

Publication number Publication date
US20120244107A1 (en) 2012-09-27
CA2780919A1 (en) 2011-04-28
EP2490728A1 (de) 2012-08-29
IN2012DN03446A (de) 2015-10-23
JP2013508482A (ja) 2013-03-07
WO2011047789A1 (de) 2011-04-28
KR20120098638A (ko) 2012-09-05
AU2010310208A1 (en) 2012-05-10
BR112012009266A2 (pt) 2016-05-31
CN102573947A (zh) 2012-07-11
WO2011047789A8 (de) 2012-05-03

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