WO2010130260A9 - Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide - Google Patents
Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide Download PDFInfo
- Publication number
- WO2010130260A9 WO2010130260A9 PCT/DK2010/050101 DK2010050101W WO2010130260A9 WO 2010130260 A9 WO2010130260 A9 WO 2010130260A9 DK 2010050101 W DK2010050101 W DK 2010050101W WO 2010130260 A9 WO2010130260 A9 WO 2010130260A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dimethyl
- morpholin
- phenyl
- butyramide
- stable forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2761383A CA2761383A1 (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
AU2010246724A AU2010246724B2 (en) | 2009-05-11 | 2010-05-11 | Stable forms of N-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl- butyramide |
MA34435A MA33351B1 (en) | 2009-05-11 | 2010-05-11 | Stable form n (2.6 dimethyl 4-morpholine 4-phenyl) |
EP10719726A EP2430008A2 (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
BRPI1013930A BRPI1013930A2 (en) | 2009-05-11 | 2010-05-11 | "compound, pharmaceutical composition, method for treating a disease, use of a compound, and process for making a compound." |
JP2012510116A JP2012526152A (en) | 2009-05-11 | 2010-05-11 | Stable form of N- (2,6-dimethyl-4-morpholin-4-yl-phenyl) -3,3-dimethyl-butyramide |
CN2010800321765A CN102459208A (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
NZ596738A NZ596738A (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
SG2011082492A SG175968A1 (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
EA201171381A EA201171381A1 (en) | 2009-05-11 | 2010-05-11 | STABLE FORMS N- (2,6-DIMETHYL-4-MORFOLIN-4-ILPHENYL) -3,3-DIMETYLBUTYRAMIDE |
MX2011011885A MX2011011885A (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dime thyl-butyramide. |
IL216148A IL216148A0 (en) | 2009-05-11 | 2011-11-03 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
TNP2011000557A TN2011000557A1 (en) | 2009-05-11 | 2011-11-04 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
ZA2011/08112A ZA201108112B (en) | 2009-05-11 | 2011-11-04 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200900597 | 2009-05-11 | ||
DKPA200900597 | 2009-11-05 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2010130260A2 WO2010130260A2 (en) | 2010-11-18 |
WO2010130260A3 WO2010130260A3 (en) | 2011-06-16 |
WO2010130260A9 true WO2010130260A9 (en) | 2012-10-18 |
Family
ID=42237259
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK2010/050101 WO2010130260A2 (en) | 2009-05-11 | 2010-05-11 | Stable forms of n-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP2430008A2 (en) |
JP (1) | JP2012526152A (en) |
KR (1) | KR20120022934A (en) |
CN (1) | CN102459208A (en) |
AR (1) | AR076556A1 (en) |
AU (1) | AU2010246724B2 (en) |
BR (1) | BRPI1013930A2 (en) |
CA (1) | CA2761383A1 (en) |
CL (1) | CL2011002814A1 (en) |
CO (1) | CO6460741A2 (en) |
CR (1) | CR20110590A (en) |
DO (1) | DOP2011000351A (en) |
EA (1) | EA201171381A1 (en) |
GE (1) | GEP20146006B (en) |
IL (1) | IL216148A0 (en) |
MA (1) | MA33351B1 (en) |
MX (1) | MX2011011885A (en) |
NZ (1) | NZ596738A (en) |
SG (1) | SG175968A1 (en) |
TN (1) | TN2011000557A1 (en) |
TW (1) | TW201041857A (en) |
WO (1) | WO2010130260A2 (en) |
ZA (1) | ZA201108112B (en) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI349666B (en) * | 2004-03-12 | 2011-10-01 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivatives |
CN101563085A (en) * | 2006-08-23 | 2009-10-21 | 威朗国际制药公司 | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US20100256145A1 (en) * | 2007-08-01 | 2010-10-07 | H. Lundbeck A/S | Use of kcnq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted |
-
2010
- 2010-05-06 TW TW099114459A patent/TW201041857A/en unknown
- 2010-05-10 AR ARP100101588A patent/AR076556A1/en unknown
- 2010-05-11 WO PCT/DK2010/050101 patent/WO2010130260A2/en active Application Filing
- 2010-05-11 BR BRPI1013930A patent/BRPI1013930A2/en not_active IP Right Cessation
- 2010-05-11 CN CN2010800321765A patent/CN102459208A/en active Pending
- 2010-05-11 EA EA201171381A patent/EA201171381A1/en unknown
- 2010-05-11 MX MX2011011885A patent/MX2011011885A/en not_active Application Discontinuation
- 2010-05-11 AU AU2010246724A patent/AU2010246724B2/en not_active Ceased
- 2010-05-11 MA MA34435A patent/MA33351B1/en unknown
- 2010-05-11 KR KR1020117026958A patent/KR20120022934A/en not_active Application Discontinuation
- 2010-05-11 NZ NZ596738A patent/NZ596738A/en not_active IP Right Cessation
- 2010-05-11 CA CA2761383A patent/CA2761383A1/en not_active Abandoned
- 2010-05-11 EP EP10719726A patent/EP2430008A2/en not_active Withdrawn
- 2010-05-11 SG SG2011082492A patent/SG175968A1/en unknown
- 2010-05-11 JP JP2012510116A patent/JP2012526152A/en active Pending
- 2010-05-11 GE GEAP201012498A patent/GEP20146006B/en unknown
-
2011
- 2011-11-03 IL IL216148A patent/IL216148A0/en unknown
- 2011-11-04 TN TNP2011000557A patent/TN2011000557A1/en unknown
- 2011-11-04 ZA ZA2011/08112A patent/ZA201108112B/en unknown
- 2011-11-10 CL CL2011002814A patent/CL2011002814A1/en unknown
- 2011-11-11 DO DO2011000351A patent/DOP2011000351A/en unknown
- 2011-11-11 CO CO11153611A patent/CO6460741A2/en not_active Application Discontinuation
- 2011-11-11 CR CR20110590A patent/CR20110590A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2010130260A2 (en) | 2010-11-18 |
MX2011011885A (en) | 2011-12-06 |
AU2010246724A1 (en) | 2011-12-08 |
BRPI1013930A2 (en) | 2019-09-24 |
SG175968A1 (en) | 2011-12-29 |
GEP20146006B (en) | 2014-01-10 |
CO6460741A2 (en) | 2012-06-15 |
DOP2011000351A (en) | 2012-01-31 |
MA33351B1 (en) | 2012-06-01 |
EP2430008A2 (en) | 2012-03-21 |
JP2012526152A (en) | 2012-10-25 |
TN2011000557A1 (en) | 2013-05-24 |
AU2010246724B2 (en) | 2013-03-21 |
KR20120022934A (en) | 2012-03-12 |
WO2010130260A3 (en) | 2011-06-16 |
CA2761383A1 (en) | 2010-11-18 |
NZ596738A (en) | 2013-04-26 |
AR076556A1 (en) | 2011-06-22 |
TW201041857A (en) | 2010-12-01 |
CR20110590A (en) | 2012-02-22 |
ZA201108112B (en) | 2013-01-30 |
CN102459208A (en) | 2012-05-16 |
EA201171381A1 (en) | 2012-05-30 |
CL2011002814A1 (en) | 2012-04-13 |
IL216148A0 (en) | 2012-01-31 |
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