WO2008148917A3 - Production method for a micrometric fluid focusing device - Google Patents

Production method for a micrometric fluid focusing device Download PDF

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Publication number
WO2008148917A3
WO2008148917A3 PCT/ES2008/000413 ES2008000413W WO2008148917A3 WO 2008148917 A3 WO2008148917 A3 WO 2008148917A3 ES 2008000413 W ES2008000413 W ES 2008000413W WO 2008148917 A3 WO2008148917 A3 WO 2008148917A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
production method
focusing device
enables
fluid focusing
Prior art date
Application number
PCT/ES2008/000413
Other languages
Spanish (es)
French (fr)
Other versions
WO2008148917A2 (en
Inventor
Estepa Antonio Luque
Reboul Jose Manuel Quero
Sanchez Francisco Antonio Perdigones
Calvo Alfonso Miguel Ganan
Original Assignee
Univ Sevilla
Estepa Antonio Luque
Reboul Jose Manuel Quero
Perdigones Sanchez Francisco A
Calvo Alfonso Miguel Ganan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sevilla, Estepa Antonio Luque, Reboul Jose Manuel Quero, Perdigones Sanchez Francisco A, Calvo Alfonso Miguel Ganan filed Critical Univ Sevilla
Publication of WO2008148917A2 publication Critical patent/WO2008148917A2/en
Publication of WO2008148917A3 publication Critical patent/WO2008148917A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0433—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of gas surrounded by an external conduit of liquid upstream the mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B05B7/0884—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point the outlet orifices for jets constituted by a liquid or a mixture containing a liquid being aligned
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00119—Arrangement of basic structures like cavities or channels, e.g. suitable for microfluidic systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00—Manufacture or treatment of microstructural devices or systems
    • B81C2201/01—Manufacture or treatment of microstructural devices or systems in or on a substrate
    • B81C2201/0174—Manufacture or treatment of microstructural devices or systems in or on a substrate for making multi-layered devices, film deposition or growing
    • B81C2201/019—Bonding or gluing multiple substrate layers

Abstract

The invention relates to a production method for a device intended to disperse or 'focus' a fluid in a precise, controlled manner at a micrometer scale, using the flow focusing technique and devices produced in accordance with said method. According to the invention, the method enables the simple production of a device that can produce coaxial flows of fluids (three-dimensional encapsulation). The production process, which is based on standard techniques used in microsystem technology (microelectromechanical systems or MEMS), enables the low-cost mass production of dispersion devices having micrometer precision and a very reduced size. The device produced can be easily built into two-dimensional matrices and coaxial flows can be created in the direction perpendicular to the matrix
PCT/ES2008/000413 2007-06-06 2008-06-05 Production method for a micrometric fluid focusing device WO2008148917A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200701626 2007-06-06
ES200701626A ES2310967B2 (en) 2007-06-06 2007-06-06 MANUFACTURING METHOD FOR M ICROMETRIC SCALE FLUID FOCUSING DEVICE

Publications (2)

Publication Number Publication Date
WO2008148917A2 WO2008148917A2 (en) 2008-12-11
WO2008148917A3 true WO2008148917A3 (en) 2009-01-29

Family

ID=40094229

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2008/000413 WO2008148917A2 (en) 2007-06-06 2008-06-05 Production method for a micrometric fluid focusing device

Country Status (2)

Country Link
ES (1) ES2310967B2 (en)
WO (1) WO2008148917A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9091434B2 (en) 2008-04-18 2015-07-28 The Board Of Trustees Of The University Of Alabama Meso-scaled combustion system
CN104865002B (en) * 2015-05-05 2017-04-12 苏州曼普拉斯传感科技有限公司 MEMS pressure sensor device and packaging method thereof
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2199048A1 (en) * 2002-02-04 2004-02-01 Univ Sevilla Capillary jets and micro/nanometric particles production device uses electrohydrodynamic force, fluid-dynamic force and specific geometry to produce micro or nano capsules which are disintegrated to form drops of micro or nano size
US20040233424A1 (en) * 2003-05-21 2004-11-25 National Cheng Kung University Chip-based microfluidic particle detector with three dimensional focusing mechanisms
US20040266022A1 (en) * 2003-06-26 2004-12-30 Narayanan Sundararajan Hydrodynamic Focusing Devices
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
ES2273572A1 (en) * 2005-05-04 2007-05-01 Universidad De Sevilla Method of preparing micro- and nanometric particles with labile products

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2199048A1 (en) * 2002-02-04 2004-02-01 Univ Sevilla Capillary jets and micro/nanometric particles production device uses electrohydrodynamic force, fluid-dynamic force and specific geometry to produce micro or nano capsules which are disintegrated to form drops of micro or nano size
US20040233424A1 (en) * 2003-05-21 2004-11-25 National Cheng Kung University Chip-based microfluidic particle detector with three dimensional focusing mechanisms
US20040266022A1 (en) * 2003-06-26 2004-12-30 Narayanan Sundararajan Hydrodynamic Focusing Devices
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
ES2273572A1 (en) * 2005-05-04 2007-05-01 Universidad De Sevilla Method of preparing micro- and nanometric particles with labile products

Also Published As

Publication number Publication date
ES2310967A1 (en) 2009-01-16
WO2008148917A2 (en) 2008-12-11
ES2310967B2 (en) 2009-07-21

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