WO2008108323A1 - インフルエンザ治療剤 - Google Patents
インフルエンザ治療剤 Download PDFInfo
- Publication number
- WO2008108323A1 WO2008108323A1 PCT/JP2008/053738 JP2008053738W WO2008108323A1 WO 2008108323 A1 WO2008108323 A1 WO 2008108323A1 JP 2008053738 W JP2008053738 W JP 2008053738W WO 2008108323 A1 WO2008108323 A1 WO 2008108323A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- influenza
- drug
- treatment
- prevention
- disclosed
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 206010022000 influenza Diseases 0.000 title 1
- 206010064097 avian influenza Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Abstract
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES08721158T ES2372996T3 (es) | 2007-03-07 | 2008-03-03 | Fármaco para el tratamiento de gripe. |
PL08721158T PL2123271T3 (pl) | 2007-03-07 | 2008-03-03 | Lek do leczenia grypy |
US12/449,909 US20100204314A1 (en) | 2007-03-07 | 2008-03-03 | Drug for treatment of influenza |
EP08721158A EP2123271B1 (en) | 2007-03-07 | 2008-03-03 | Drug for treatment of influenza |
SI200830440T SI2123271T1 (sl) | 2007-03-07 | 2008-03-03 | Zdravilo za zdravljenje influence |
DK08721158.7T DK2123271T3 (da) | 2007-03-07 | 2008-03-03 | Lægemiddel til behandling af influenza |
CN2008800149108A CN101715343B (zh) | 2007-03-07 | 2008-03-03 | 流感治疗药 |
CA002680415A CA2680415A1 (en) | 2007-03-07 | 2008-03-03 | Neuraminic acid derivatives useful in the treatment of influenza |
AT08721158T ATE526960T1 (de) | 2007-03-07 | 2008-03-03 | Arzneimittel zur behandlung von grippe |
JP2009502568A JP5286251B2 (ja) | 2007-03-07 | 2008-03-03 | インフルエンザ治療剤 |
HK10103858.3A HK1137142A1 (en) | 2007-03-07 | 2010-04-21 | Drug for treatment of influenza |
HR20110861T HRP20110861T1 (hr) | 2007-03-07 | 2011-11-21 | Lijek za liječenje gripe |
US14/010,784 US20140018418A1 (en) | 2007-03-07 | 2013-08-27 | Methods of treating or preventing h5n1 influenza |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-056872 | 2007-03-07 | ||
JP2007056872 | 2007-03-07 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/010,784 Division US20140018418A1 (en) | 2007-03-07 | 2013-08-27 | Methods of treating or preventing h5n1 influenza |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008108323A1 true WO2008108323A1 (ja) | 2008-09-12 |
Family
ID=39738201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/053738 WO2008108323A1 (ja) | 2007-03-07 | 2008-03-03 | インフルエンザ治療剤 |
Country Status (17)
Country | Link |
---|---|
US (2) | US20100204314A1 (ja) |
EP (1) | EP2123271B1 (ja) |
JP (2) | JP5286251B2 (ja) |
KR (1) | KR101473028B1 (ja) |
CN (1) | CN101715343B (ja) |
AT (1) | ATE526960T1 (ja) |
CA (1) | CA2680415A1 (ja) |
CY (1) | CY1112201T1 (ja) |
DK (1) | DK2123271T3 (ja) |
ES (1) | ES2372996T3 (ja) |
HK (1) | HK1137142A1 (ja) |
HR (1) | HRP20110861T1 (ja) |
PL (1) | PL2123271T3 (ja) |
PT (1) | PT2123271E (ja) |
SI (1) | SI2123271T1 (ja) |
TW (1) | TWI424841B (ja) |
WO (1) | WO2008108323A1 (ja) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
ES2442024T3 (es) | 2008-07-15 | 2014-02-07 | Academia Sinica | Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados |
US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
WO2011130332A1 (en) | 2010-04-12 | 2011-10-20 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
CN104777301B (zh) * | 2010-05-10 | 2018-04-20 | 中央研究院 | 具有抗流感活性的扎那米韦膦酸酯同类物及流感病毒的奥司他韦易感性的测定 |
EP2792676A4 (en) * | 2011-12-16 | 2015-10-07 | Daiichi Sankyo Co Ltd | PROCESS FOR PREPARING NEURAMINE ACID DERIVATIVES |
US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
US9914956B2 (en) | 2012-08-18 | 2018-03-13 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
CA2923579C (en) | 2013-09-06 | 2023-09-05 | Academia Sinica | Human inkt cell activation using glycolipids with altered glycosyl groups |
US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
AU2015206370A1 (en) | 2014-01-16 | 2016-07-07 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
CN106415244B (zh) | 2014-03-27 | 2020-04-24 | 中央研究院 | 反应性标记化合物及其用途 |
EP3149037A4 (en) | 2014-05-27 | 2018-01-10 | Academia Sinica | Anti-her2 glycoantibodies and uses thereof |
KR20230033737A (ko) | 2014-05-27 | 2023-03-08 | 아카데미아 시니카 | 증진된 항체 효능을 위한 범용 당형태에 관한 조성물 및 방법 |
KR20220151036A (ko) | 2014-05-27 | 2022-11-11 | 아카데미아 시니카 | 항-cd20 글리코항체 및 이의 용도 |
US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
KR102494193B1 (ko) | 2014-05-28 | 2023-01-31 | 아카데미아 시니카 | 항-tnf-알파 글리코항체 및 이의 용도 |
WO2016040369A2 (en) | 2014-09-08 | 2016-03-17 | Academia Sinica | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS |
US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
CA2972072A1 (en) | 2015-01-24 | 2016-07-28 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
JP2019515876A (ja) | 2016-03-08 | 2019-06-13 | アカデミア シニカAcademia Sinica | N−グリカンおよびそのアレイのモジュール合成のための方法 |
JP7213549B2 (ja) | 2016-08-22 | 2023-01-27 | シーエイチオー ファーマ インコーポレイテッド | 抗体、結合性断片、および使用の方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10109981A (ja) | 1996-08-13 | 1998-04-28 | Sankyo Co Ltd | ノイラミン酸化合物 |
JPH10330373A (ja) * | 1996-07-22 | 1998-12-15 | Sankyo Co Ltd | ノイラミン酸誘導体 |
JP2002012590A (ja) | 2000-04-25 | 2002-01-15 | Sankyo Co Ltd | ノイラミン酸化合物の水和物及び結晶 |
US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
US6844363B2 (en) | 2000-04-25 | 2005-01-18 | Sankyo Company, Limited | Hydrates of a neuraminic acid compound and crystalline forms thereof |
JP2007056872A (ja) | 2005-08-22 | 2007-03-08 | Delphi Technologies Inc | カムシャフトとタイミングギアとの間のタイミングを制御するためのフェーザ |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0823428B1 (en) * | 1996-07-22 | 2002-01-02 | Sankyo Company Limited | Neuraminic acid derivatives, their preparation and their medical use |
-
2008
- 2008-03-03 ES ES08721158T patent/ES2372996T3/es active Active
- 2008-03-03 CA CA002680415A patent/CA2680415A1/en not_active Abandoned
- 2008-03-03 AT AT08721158T patent/ATE526960T1/de active
- 2008-03-03 US US12/449,909 patent/US20100204314A1/en not_active Abandoned
- 2008-03-03 PL PL08721158T patent/PL2123271T3/pl unknown
- 2008-03-03 DK DK08721158.7T patent/DK2123271T3/da active
- 2008-03-03 EP EP08721158A patent/EP2123271B1/en not_active Not-in-force
- 2008-03-03 KR KR1020097018422A patent/KR101473028B1/ko active IP Right Grant
- 2008-03-03 PT PT08721158T patent/PT2123271E/pt unknown
- 2008-03-03 CN CN2008800149108A patent/CN101715343B/zh active Active
- 2008-03-03 JP JP2009502568A patent/JP5286251B2/ja active Active
- 2008-03-03 WO PCT/JP2008/053738 patent/WO2008108323A1/ja active Application Filing
- 2008-03-03 SI SI200830440T patent/SI2123271T1/sl unknown
- 2008-03-07 TW TW097107984A patent/TWI424841B/zh active
-
2010
- 2010-04-21 HK HK10103858.3A patent/HK1137142A1/xx unknown
-
2011
- 2011-11-21 HR HR20110861T patent/HRP20110861T1/hr unknown
- 2011-12-30 CY CY20111101293T patent/CY1112201T1/el unknown
-
2013
- 2013-04-22 JP JP2013089202A patent/JP6012076B2/ja active Active
- 2013-08-27 US US14/010,784 patent/US20140018418A1/en not_active Abandoned
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10330373A (ja) * | 1996-07-22 | 1998-12-15 | Sankyo Co Ltd | ノイラミン酸誘導体 |
JP3209946B2 (ja) | 1996-07-22 | 2001-09-17 | 三共株式会社 | ノイラミン酸誘導体 |
US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
JPH10109981A (ja) | 1996-08-13 | 1998-04-28 | Sankyo Co Ltd | ノイラミン酸化合物 |
JP2002012590A (ja) | 2000-04-25 | 2002-01-15 | Sankyo Co Ltd | ノイラミン酸化合物の水和物及び結晶 |
US6844363B2 (en) | 2000-04-25 | 2005-01-18 | Sankyo Company, Limited | Hydrates of a neuraminic acid compound and crystalline forms thereof |
JP2007056872A (ja) | 2005-08-22 | 2007-03-08 | Delphi Technologies Inc | カムシャフトとタイミングギアとの間のタイミングを制御するためのフェーザ |
Non-Patent Citations (7)
Title |
---|
HIROKAWA SHOTEN: "Molecular Design", vol. 7, 1990, article "Development of Pharmaceuticals", pages: 163 - 198 |
LE Q MAI ET AL.: "Avian flu: isolation of drug- resistant H5N1 virus.", NATURE, vol. 437, no. 7062, 2005, pages 1108, XP008112478 * |
MOSCONA ANNE: "Oseltamivir resistance -disabling our influenza defenses.", THE NEW ENGLAND JOURNAL OF MEDICINE, vol. 353, no. 25, 2005, pages 2633 - 2636, XP008112475, DOI: doi:10.1056/NEJMp058291 * |
N. ENGL. J. MED., vol. 353, no. 25, 2005, pages 2667 - 72 |
NATURE, vol. 437, 2005, pages 1108 |
RUPERT J. RUSSE LL ET AL.: "The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.", NATURE, vol. 443, 2006, pages 45 - 49, XP002474738 * |
See also references of EP2123271A4 |
Also Published As
Publication number | Publication date |
---|---|
PL2123271T3 (pl) | 2012-03-30 |
KR20090129414A (ko) | 2009-12-16 |
EP2123271B1 (en) | 2011-10-05 |
CN101715343A (zh) | 2010-05-26 |
JPWO2008108323A1 (ja) | 2010-06-17 |
TWI424841B (zh) | 2014-02-01 |
PT2123271E (pt) | 2011-12-20 |
ATE526960T1 (de) | 2011-10-15 |
EP2123271A4 (en) | 2010-03-17 |
TW200848018A (en) | 2008-12-16 |
CN101715343B (zh) | 2012-09-26 |
EP2123271A1 (en) | 2009-11-25 |
HRP20110861T1 (hr) | 2011-12-31 |
CY1112201T1 (el) | 2015-12-09 |
JP5286251B2 (ja) | 2013-09-11 |
JP2013139483A (ja) | 2013-07-18 |
KR101473028B1 (ko) | 2014-12-15 |
SI2123271T1 (sl) | 2012-05-31 |
US20100204314A1 (en) | 2010-08-12 |
ES2372996T3 (es) | 2012-01-30 |
JP6012076B2 (ja) | 2016-10-25 |
US20140018418A1 (en) | 2014-01-16 |
DK2123271T3 (da) | 2012-01-23 |
HK1137142A1 (en) | 2010-07-23 |
CA2680415A1 (en) | 2008-09-12 |
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