WO2007054965A3 - Process for preparation of tetrazoles from aromatic cyano derivatives - Google Patents

Process for preparation of tetrazoles from aromatic cyano derivatives Download PDF

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Publication number
WO2007054965A3
WO2007054965A3 PCT/IN2006/000346 IN2006000346W WO2007054965A3 WO 2007054965 A3 WO2007054965 A3 WO 2007054965A3 IN 2006000346 W IN2006000346 W IN 2006000346W WO 2007054965 A3 WO2007054965 A3 WO 2007054965A3
Authority
WO
WIPO (PCT)
Prior art keywords
tetrazoles
preparation
cyano derivatives
aromatic cyano
formula
Prior art date
Application number
PCT/IN2006/000346
Other languages
French (fr)
Other versions
WO2007054965A2 (en
Inventor
Pandurang Balwant Deshpande
Parvenkumar Luthra
Anandkumar Pandey
Original Assignee
Alembic Ltd
Pandurang Balwant Deshpande
Parvenkumar Luthra
Anandkumar Pandey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alembic Ltd, Pandurang Balwant Deshpande, Parvenkumar Luthra, Anandkumar Pandey filed Critical Alembic Ltd
Publication of WO2007054965A2 publication Critical patent/WO2007054965A2/en
Publication of WO2007054965A3 publication Critical patent/WO2007054965A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

The present invention relates to process for preparation of tetrazoles of formula (I) from aromatic cyano derivatives of formula (II) comprising of treating the cyano compound of formula (II) with trialkyltin halide and metal azide in presence of base.
PCT/IN2006/000346 2005-09-23 2006-09-08 Process for preparation of tetrazoles from aromatic cyano derivatives WO2007054965A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1177/MUM/2005 2005-09-23
IN1177MU2005 2005-09-23

Publications (2)

Publication Number Publication Date
WO2007054965A2 WO2007054965A2 (en) 2007-05-18
WO2007054965A3 true WO2007054965A3 (en) 2007-11-01

Family

ID=38023679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000346 WO2007054965A2 (en) 2005-09-23 2006-09-08 Process for preparation of tetrazoles from aromatic cyano derivatives

Country Status (1)

Country Link
WO (1) WO2007054965A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865912B2 (en) 2010-10-06 2014-10-21 Glaxosmithkline Llc Benzimidazole derivatives as PI3 kinase inhibitors

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8258312B2 (en) 2007-06-27 2012-09-04 Mylan Laboratories Ltd Process for preparing pure valsartan
WO2009125416A2 (en) 2008-04-07 2009-10-15 Hetero Research Foundation Process for preparation of valsartan intermediate
EP2321281A4 (en) 2008-09-02 2011-09-28 Elder Pharmaceuticals Ltd Anti inflammatory compounds
US8623928B2 (en) 2009-11-12 2014-01-07 National Research Council Of Canada Polymers of intrinsic microporosity containing tetrazole groups
US11655220B2 (en) 2020-10-22 2023-05-23 Hetero Labs Limited Process for the preparation of angiotensin II receptor blockers

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003089417A1 (en) * 2002-04-15 2003-10-30 Dr. Reddy's Laboratories Limited Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl) -n-pentanoyl-n- [2’-(1h-tetrazol-5-yl-)- biphenyl-4-yl methyl] amine (valsartan)
WO2005051929A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Conversion of aromatic nitriles into tetrazoles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003089417A1 (en) * 2002-04-15 2003-10-30 Dr. Reddy's Laboratories Limited Novel crystalline forms of (s)-n-(1-carboxy-2-methyl-prop-1-yl) -n-pentanoyl-n- [2’-(1h-tetrazol-5-yl-)- biphenyl-4-yl methyl] amine (valsartan)
WO2005051929A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Conversion of aromatic nitriles into tetrazoles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ELLINGBOE JOHN W ET AL: "Metabolites of the Angiotensin II Antagonist Tasosartan: The Importance of a Second Acidic Group", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 41, no. 22, 1998, pages 4251 - 4260, XP002389948, ISSN: 0022-2623 *
LE BOURDONNEC B ET AL: "Comparison of 3D structures and AT1 binding properties of pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones with parent antihypertensive drug irbesartan", JOURNAL OF MEDICINAL CHEMISTRY 10 OCT 2002 UNITED STATES, vol. 45, no. 21, 10 October 2002 (2002-10-10), pages 4794 - 4798, XP002440584, ISSN: 0022-2623 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865912B2 (en) 2010-10-06 2014-10-21 Glaxosmithkline Llc Benzimidazole derivatives as PI3 kinase inhibitors
US9156797B2 (en) 2010-10-06 2015-10-13 Glaxosmithkline Llc Benzimidazole derivatives as PI3 kinase inhibitors

Also Published As

Publication number Publication date
WO2007054965A2 (en) 2007-05-18

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