WO2007074491A8 - HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS - Google Patents

HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS

Info

Publication number
WO2007074491A8
WO2007074491A8 PCT/IT2006/000860 IT2006000860W WO2007074491A8 WO 2007074491 A8 WO2007074491 A8 WO 2007074491A8 IT 2006000860 W IT2006000860 W IT 2006000860W WO 2007074491 A8 WO2007074491 A8 WO 2007074491A8
Authority
WO
WIPO (PCT)
Prior art keywords
heterotricyclic
nkl
neurokinin
receptor ligands
amide derivatives
Prior art date
Application number
PCT/IT2006/000860
Other languages
French (fr)
Other versions
WO2007074491A1 (en
WO2007074491B1 (en
Inventor
Andrea Cappelli
Germano Giuliani
Maurizio Anzini
Salvatore Vomero
Original Assignee
Univ Siena
Andrea Cappelli
Germano Giuliani
Maurizio Anzini
Salvatore Vomero
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Siena, Andrea Cappelli, Germano Giuliani, Maurizio Anzini, Salvatore Vomero filed Critical Univ Siena
Publication of WO2007074491A1 publication Critical patent/WO2007074491A1/en
Publication of WO2007074491B1 publication Critical patent/WO2007074491B1/en
Publication of WO2007074491A8 publication Critical patent/WO2007074491A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

The present invention relates to compounds of formula 1, method of preparation and uses thereof.
PCT/IT2006/000860 2005-12-28 2006-12-20 HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS WO2007074491A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75494005P 2005-12-28 2005-12-28
US60/754,940 2005-12-28

Publications (3)

Publication Number Publication Date
WO2007074491A1 WO2007074491A1 (en) 2007-07-05
WO2007074491B1 WO2007074491B1 (en) 2007-08-16
WO2007074491A8 true WO2007074491A8 (en) 2007-09-20

Family

ID=37891438

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2006/000860 WO2007074491A1 (en) 2005-12-28 2006-12-20 HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS

Country Status (1)

Country Link
WO (1) WO2007074491A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2729147B1 (en) 2011-07-04 2017-09-06 IRBM - Science Park S.p.A. Nk-1 receptor antagonists for treating corneal neovascularisation
US9527835B2 (en) 2014-02-13 2016-12-27 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
SG10201806849WA (en) 2014-02-13 2018-09-27 Incyte Corp Cyclopropylamines as lsd1 inhibitors
TW201613860A (en) 2014-02-13 2016-04-16 Incyte Corp Cyclopropylamines as LSD1 inhibitors
EP3626714A1 (en) 2014-02-13 2020-03-25 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
TWI687419B (en) 2014-07-10 2020-03-11 美商英塞特公司 Imidazopyridines and imidazopyrazines as LSD1 inhibitors
US9758523B2 (en) 2014-07-10 2017-09-12 Incyte Corporation Triazolopyridines and triazolopyrazines as LSD1 inhibitors
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
US9695167B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
PE20180455A1 (en) 2015-04-03 2018-03-05 Incyte Corp HETEROCYCLIC COMPOUNDS AS LSD1 INHIBITORS
SG10202001219UA (en) 2015-08-12 2020-03-30 Incyte Corp Salts of an lsd1 inhibitor
CA3021678A1 (en) 2016-04-22 2017-10-26 Incyte Corporation Formulations of an lsd1 inhibitor
US20210015834A1 (en) 2018-02-26 2021-01-21 Ospedale San Raffaele S.R.L. Nk-1 antagonists for use in the treatment of ocular pain
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same
WO2021180885A1 (en) 2020-03-11 2021-09-16 Ospedale San Raffaele S.R.L. Treatment of stem cell deficiency

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0318727D0 (en) * 2003-08-08 2003-09-10 Smithkline Beecham Corp Novel compounds
RU2384571C2 (en) * 2004-04-28 2010-03-20 Такеда Фармасьютикал Компани Лимитед Condensed quinoline derivative and use thereof

Also Published As

Publication number Publication date
WO2007074491A1 (en) 2007-07-05
WO2007074491B1 (en) 2007-08-16

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