WO2007010504A3 - Acid addition salts of isoindoles acting as adrenergic receptor antagonists - Google Patents
Acid addition salts of isoindoles acting as adrenergic receptor antagonists Download PDFInfo
- Publication number
- WO2007010504A3 WO2007010504A3 PCT/IB2006/052516 IB2006052516W WO2007010504A3 WO 2007010504 A3 WO2007010504 A3 WO 2007010504A3 IB 2006052516 W IB2006052516 W IB 2006052516W WO 2007010504 A3 WO2007010504 A3 WO 2007010504A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- acid addition
- addition salts
- isoindoles
- acting
- receptor antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Provided herein are acid addition salts of compounds of Formula (I). The acid addition salts of Formula I described herein can be used to treat benign prostatic hyperplasia (BPH) and the related symptoms thereof. Further, these compounds can be used to treat lower urinary tract symptoms (LUTS) that may or may not be associated with BPH. Process for preparing the compounds described herein, pharmaceutical compositions thereof, and the methods of treating BPH or related symptoms thereof and LUTS that may or may not be associated with BPH are also provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1940/DEL/2005 | 2005-07-22 | ||
IN1940DE2005 | 2005-07-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007010504A2 WO2007010504A2 (en) | 2007-01-25 |
WO2007010504A3 true WO2007010504A3 (en) | 2007-04-05 |
Family
ID=37517191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2006/052516 WO2007010504A2 (en) | 2005-07-22 | 2006-07-21 | Acid addition salts of isoindoles acting as adrenergic receptor antagonists |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007010504A2 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5936661A (en) * | 1982-08-26 | 1984-02-28 | Eisai Co Ltd | Carboxylic acid imide derivative, its preparation and drug containing the same |
WO2003084928A1 (en) * | 2002-04-08 | 2003-10-16 | Ranbaxy Laboratories Limited | Alpha, omega-dicarboximide derivatives as useful uro-selective α1α adrenoceptor blockers |
WO2005037282A1 (en) * | 2003-10-15 | 2005-04-28 | Ranbaxy Laboratories Limited | 1-alkylpiperazinyl-pyrrolidin-2,5-dione derivatives as adrenergic receptor antagonists |
WO2005118537A2 (en) * | 2004-05-31 | 2005-12-15 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives as adrenergic receptor antagonists |
WO2006092710A1 (en) * | 2005-03-02 | 2006-09-08 | Ranbaxy Laboratories Limited | Metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a-tetrahydro-1h-isoindole-1,3-(2h)-dione |
-
2006
- 2006-07-21 WO PCT/IB2006/052516 patent/WO2007010504A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5936661A (en) * | 1982-08-26 | 1984-02-28 | Eisai Co Ltd | Carboxylic acid imide derivative, its preparation and drug containing the same |
WO2003084928A1 (en) * | 2002-04-08 | 2003-10-16 | Ranbaxy Laboratories Limited | Alpha, omega-dicarboximide derivatives as useful uro-selective α1α adrenoceptor blockers |
WO2005037282A1 (en) * | 2003-10-15 | 2005-04-28 | Ranbaxy Laboratories Limited | 1-alkylpiperazinyl-pyrrolidin-2,5-dione derivatives as adrenergic receptor antagonists |
WO2005118537A2 (en) * | 2004-05-31 | 2005-12-15 | Ranbaxy Laboratories Limited | Arylpiperazine derivatives as adrenergic receptor antagonists |
WO2006092710A1 (en) * | 2005-03-02 | 2006-09-08 | Ranbaxy Laboratories Limited | Metabolites of 2-{3-[4-(2-isopropoxyphenyl) piperazin-1-yl]-propyl}-3a,4,7,7a-tetrahydro-1h-isoindole-1,3-(2h)-dione |
Also Published As
Publication number | Publication date |
---|---|
WO2007010504A2 (en) | 2007-01-25 |
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