WO2006133672A3 - Verfahren und vorrichtung zur detektion von analyten in fluiden medien - Google Patents
Verfahren und vorrichtung zur detektion von analyten in fluiden medien Download PDFInfo
- Publication number
- WO2006133672A3 WO2006133672A3 PCT/DE2006/000979 DE2006000979W WO2006133672A3 WO 2006133672 A3 WO2006133672 A3 WO 2006133672A3 DE 2006000979 W DE2006000979 W DE 2006000979W WO 2006133672 A3 WO2006133672 A3 WO 2006133672A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fluid media
- cantilever probe
- pillar
- column
- detecting analytes
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N9/00—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity
- G01N9/002—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity using variation of the resonant frequency of an element vibrating in contact with the material submitted to analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/04—Wave modes and trajectories
- G01N2291/042—Wave modes
- G01N2291/0427—Flexural waves, plate waves, e.g. Lamb waves, tuning fork, cantilever
Landscapes
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Length Measuring Devices With Unspecified Measuring Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Abstract
Die Erfindung betrifft Verfahren und eine Vorrichtung zur Detektion von Analyten in fluiden Medien mittels einer Cantileversonde. Sie betrifft weiterhin die Verwendung des Verfahrens bzw. der Vorrichtung. Um ein derartiges Verfahren bzw. eine derartige Vorrichtung mit höherer Meßempfindlichkeit zu schaffen, wird im Rahmen der Erfindung vorgeschlagen, daß eine säulen- oder pfeilerartige Cantileversonde verwendet wird, deren Mantelfläche von einem Luftspalt umgeben ist und deren Deckel dem fluiden Medium ausgesetzt ist und die sensitive Fläche darstellt. Durch Verwendung der säulen- oder pfeilerartigen Cantileversonde, also einen einseitig eingespannten mechanischen Schwinger, dessen Eigenschwingung durch Materialablagerung aus einem fluiden Medium auf dem Deckel des säulen- oder pfeilerartigen Cantilevers gedämpft wird und somit seine Resonanzfrequenz, Dämpfung bzw. Amplitude durch die Massenzunahme verändert, wird die Meßempfindlichkeit gegenüber bekannten Verfahren deutlich erhöht.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE200510027788 DE102005027788B4 (de) | 2005-06-15 | 2005-06-15 | Verfahren und Vorrichtung zur Detektion von Analyten in flüssigen Medien |
DE102005027788.8 | 2005-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006133672A2 WO2006133672A2 (de) | 2006-12-21 |
WO2006133672A3 true WO2006133672A3 (de) | 2007-02-15 |
Family
ID=36940172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2006/000979 WO2006133672A2 (de) | 2005-06-15 | 2006-06-07 | Verfahren und vorrichtung zur detektion von analyten in fluiden medien |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE102005027788B4 (de) |
WO (1) | WO2006133672A2 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102021134179A1 (de) | 2021-12-21 | 2023-06-22 | Truedyne Sensors AG | Messanordnung mit einem mikromechanischen Oszillator |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19838284C1 (de) * | 1998-08-24 | 2000-05-04 | Lorenz Walder | Vorrichtung zur Bestimmung der Dichte einer Flüssigkeit |
WO2000066266A1 (en) * | 1999-05-03 | 2000-11-09 | Cantion A/S | Sensor for microfluid handling system |
US20050103097A1 (en) * | 2002-01-24 | 2005-05-19 | Carsten Faltum | Sensor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020115198A1 (en) * | 2000-09-20 | 2002-08-22 | Nerenberg Michael I. | Microfabricated ultrasound array for use as resonant sensors |
AU2003299534A1 (en) * | 2002-08-29 | 2004-05-13 | Bioscale, Inc. | Resonant sensor and sensing system |
-
2005
- 2005-06-15 DE DE200510027788 patent/DE102005027788B4/de not_active Expired - Fee Related
-
2006
- 2006-06-07 WO PCT/DE2006/000979 patent/WO2006133672A2/de active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19838284C1 (de) * | 1998-08-24 | 2000-05-04 | Lorenz Walder | Vorrichtung zur Bestimmung der Dichte einer Flüssigkeit |
WO2000066266A1 (en) * | 1999-05-03 | 2000-11-09 | Cantion A/S | Sensor for microfluid handling system |
US20050103097A1 (en) * | 2002-01-24 | 2005-05-19 | Carsten Faltum | Sensor |
Non-Patent Citations (2)
Title |
---|
B.ILIC ET AL: "Single cell detection with micromechanical oscillators", JOURNAL OF VACUUM SCIENCE AND TECHNOLOGY B, vol. 19, no. 6, December 2001 (2001-12-01), pages 2825 - 2828, XP002398539 * |
CHRISTIANE ZIEGLER: "Cantilever-based biosensors", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 379, no. 7-8, December 2004 (2004-12-01), pages 946 - 959, XP002398538 * |
Also Published As
Publication number | Publication date |
---|---|
DE102005027788A1 (de) | 2007-01-04 |
WO2006133672A2 (de) | 2006-12-21 |
DE102005027788B4 (de) | 2008-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101371132B (zh) | 自励、自感知压电悬臂梁传感器 | |
Thiruvenkatanathan et al. | Limits to mode-localized sensing using micro-and nanomechanical resonator arrays | |
Roy et al. | Fluid density sensing using piezoelectric micromachined ultrasound transducers | |
US7694552B2 (en) | High quality factor resonators for liquid immersion biological and chemical sensors | |
WO2006112878A3 (en) | Apparatus and method for providing a fluid cut measurement of a multi-liquid mixture compensated for entrained gas | |
WO2003104767A3 (en) | PHOTOACOUSTIC SPECTROSCOPY REINFORCED WITH QUARTZ | |
WO2008110746A3 (en) | Measuring apparatus | |
Truax et al. | Mass-sensitive detection of gas-phase volatile organics using disk microresonators | |
WO2006021691A8 (fr) | Procede et dispositif de determination de biomasse dans un milieu, notamment d’un milieu contenant des cellules biologiques, et appareil de mesure mettant en oeuvre ce procede | |
ATE487132T1 (de) | Vorrichtung mit piezoakustischem resonatorelement und deren verwendung zur ausgabe eines signals in abhängigkeit einer resonanzfrequenz | |
JP2010002413A (ja) | 圧電センサ及び感知装置 | |
CN109374729A (zh) | 一种声学微质量传感器及检测方法 | |
Pratap et al. | Fluid spectroscopy with piezoelectric ultrasound mems transducers | |
WO2007087936A3 (de) | Vorrichtung und verfahren zur detektion einer substanz in einer flüssigkeit | |
WO2005118143A3 (en) | Methods and apparatus for label-independent monitoring of biological interactions on sensitized substrates | |
Hu et al. | Design, fabrication and characterization of a piezoelectric MEMS diaphragm resonator mass sensor | |
Wang et al. | A micro-machined thin film electro-acoustic biosensor for detection of pesticide residuals | |
CN108801438B (zh) | 一种基于光学干涉的振动位移测量装置 | |
WO2006133672A3 (de) | Verfahren und vorrichtung zur detektion von analyten in fluiden medien | |
Riesch et al. | A novel sensor system for liquid properties based on a micromachined beam and a low-cost optical readout | |
Quang-Khang et al. | Acoustic emission sensor using liquid-on-beam structure | |
US8302478B2 (en) | Magnetostrictive substance detection system and method | |
Passian et al. | Piezoresistive detection of acoustic waves | |
US10119856B2 (en) | Method for detecting a perturbation by hysteretic cycle using a nonlinear electromechanical resonator and device using the method | |
US7657947B2 (en) | Method and device for the contactless excitation of torsional vibrations in a one-sidedly clamped-in spring cantilever of an atomic force microscope |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
122 | Ep: pct application non-entry in european phase |
Ref document number: 06753253 Country of ref document: EP Kind code of ref document: A2 |