WO2006121799A3 - Detection d'analytes fondee sur des cristaux liquides - Google Patents

Detection d'analytes fondee sur des cristaux liquides Download PDF

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Publication number
WO2006121799A3
WO2006121799A3 PCT/US2006/017261 US2006017261W WO2006121799A3 WO 2006121799 A3 WO2006121799 A3 WO 2006121799A3 US 2006017261 W US2006017261 W US 2006017261W WO 2006121799 A3 WO2006121799 A3 WO 2006121799A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid crystal
analyte detection
crystal based
detection
based analyte
Prior art date
Application number
PCT/US2006/017261
Other languages
English (en)
Other versions
WO2006121799A2 (fr
Inventor
Barbara Israel
Doug Hansmann
Nicholas Abbott
Original Assignee
Platypus Technologies Llc
Barbara Israel
Doug Hansmann
Nicholas Abbott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Platypus Technologies Llc, Barbara Israel, Doug Hansmann, Nicholas Abbott filed Critical Platypus Technologies Llc
Priority to CA002606916A priority Critical patent/CA2606916A1/fr
Priority to EP06759092A priority patent/EP1888781A4/fr
Priority to AU2006244486A priority patent/AU2006244486A1/en
Publication of WO2006121799A2 publication Critical patent/WO2006121799A2/fr
Publication of WO2006121799A3 publication Critical patent/WO2006121799A3/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention se rapporte au domaine de la détection des analytes, et en particulier à la détection d'analytes au moyen d'une procédure d'analyse basée sur des cristaux liquides. Dans la présente invention, la liaison à des analytes dans une région de détection est identifiée par des changements dans l'orientation des cristaux liquides provoqués par l'orientation indépendante de la liaison aux analytes elle-même due à toute topographie associée à la région de détection.
PCT/US2006/017261 2005-05-06 2006-05-05 Detection d'analytes fondee sur des cristaux liquides WO2006121799A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002606916A CA2606916A1 (fr) 2005-05-06 2006-05-05 Detection d'analytes fondee sur des cristaux liquides
EP06759092A EP1888781A4 (fr) 2005-05-06 2006-05-05 Détection d'analytes fondée sur des cristaux liquides
AU2006244486A AU2006244486A1 (en) 2005-05-06 2006-05-05 Liquid crystal based analyte detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67842605P 2005-05-06 2005-05-06
US60/678,426 2005-05-06

Publications (2)

Publication Number Publication Date
WO2006121799A2 WO2006121799A2 (fr) 2006-11-16
WO2006121799A3 true WO2006121799A3 (fr) 2007-01-25

Family

ID=37397105

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/017261 WO2006121799A2 (fr) 2005-05-06 2006-05-05 Detection d'analytes fondee sur des cristaux liquides

Country Status (5)

Country Link
US (1) US20070042505A1 (fr)
EP (1) EP1888781A4 (fr)
AU (1) AU2006244486A1 (fr)
CA (1) CA2606916A1 (fr)
WO (1) WO2006121799A2 (fr)

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US7666661B2 (en) 2001-08-27 2010-02-23 Platypus Technologies, Llc Substrates, devices, and methods for quantitative liquid crystal assays
WO2004041061A2 (fr) * 2002-05-22 2004-05-21 Platypus Technologies, Llc Substrats, dispositifs et procedes d'analyses cellulaires
EP1654390B1 (fr) 2003-07-25 2009-11-11 Platypus Technologies, LLC Detection d'analyte a base de cristaux liquides
CA2545482A1 (fr) 2003-11-10 2005-05-26 Platypus Technologies, Llc Substrats, dispositifs et procedes de dosages cellulaires
US7531366B2 (en) * 2004-07-23 2009-05-12 Platypus Technologies, Llc Bead based assays using a liquid crystal reporter
US7662572B2 (en) 2005-08-25 2010-02-16 Platypus Technologies, Llc. Compositions and liquid crystals
US7842499B2 (en) * 2006-08-07 2010-11-30 Platypus Technologies, Llc Substrates, devices, and methods for cellular assays
JP2010509593A (ja) 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ バイオポリマーセンサーおよびその製造方法
WO2008118211A2 (fr) * 2006-11-03 2008-10-02 Trustees Of Tufts College Cristaux photoniques biopolymères et procédés de fabrication de ceux-ci
US8574461B2 (en) * 2006-11-03 2013-11-05 Tufts University Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same
EP2086749B1 (fr) 2006-11-03 2013-05-08 Trustees Of Tufts College Dispositif optique de biopolymère à nanomotifs et procédé de fabrication de celui-ci
US20100227323A1 (en) * 2007-07-30 2010-09-09 Cornell Research Foundation, Inc. Microchannel detection device and use thereof
WO2009026359A2 (fr) 2007-08-20 2009-02-26 Platypus Technologies, Llc Dispositifs améliorés pour dosages cellulaires
CA2742844C (fr) 2007-11-05 2017-02-28 Trustees Of Tufts College Fabrication de structures photoniques de fibroine de soie par impression par nanocontact
US20090260995A1 (en) * 2008-04-16 2009-10-22 Keith Warriner Polymer based biosensor
US8472683B2 (en) * 2008-05-09 2013-06-25 General Electric Company Motion correction in tomographic images
US20110135697A1 (en) * 2008-06-18 2011-06-09 Trustees Of Tufts College Edible holographic silk products
US20100084081A1 (en) * 2008-08-06 2010-04-08 Academia Sinica Method for Fabricating Organic Optoelectronic Multi-Layer Devices
TWI463714B (zh) * 2008-08-21 2014-12-01 Academia Sinica 形成有機薄膜光電元件的方法
WO2010031047A2 (fr) 2008-09-15 2010-03-18 Platypus Technologies, Llc Détection de composés en phase vapeur par des changements de propriétés physiques d'un cristal liquide
US20110200986A1 (en) * 2008-10-06 2011-08-18 National University Of Singapore Bio-assay using liquid crystals
AU2009322607B2 (en) * 2008-12-01 2015-05-14 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detection of complement fixing antibodies
WO2010088585A1 (fr) * 2009-01-30 2010-08-05 Trustees Of Boston University Détecteur chimique/biologique employant des composants chromatiques diffusés dans des surfaces apériodiques à motifs nanoscopiques
CA2789009C (fr) 2009-02-12 2017-03-21 Trustees Of Tufts College Lithographie par nano-impression de structures de fibroine de soie pour des applications biomedicales et biophotoniques
US8925373B2 (en) * 2009-04-22 2015-01-06 Wisconsin Alumni Research Foundation Microfluidic device integrating sensing element and method
JP2012533780A (ja) 2009-07-20 2012-12-27 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ タンパク質のみからなる移植可能な吸収性反射体
WO2011026101A2 (fr) 2009-08-31 2011-03-03 Trustees Of Tufts College Dispositifs à transistor à base de soie
WO2011058488A1 (fr) * 2009-11-12 2011-05-19 Koninklijke Philips Electronics N.V. Ensemble porte-puce pour un capteur à réseau de fils
WO2011060184A1 (fr) * 2009-11-12 2011-05-19 Cermed Corporation Dépistage du cancer cervical par la détection moléculaire de la néoplasie induite par le papillomavirus humain
US9372142B2 (en) * 2012-02-27 2016-06-21 Wisconsin Alumni Research Foundation Liquid crystal device and method for screening protein stabilizing agents or optimal protein concentrations to prevent unfolding
JP6548631B2 (ja) 2013-03-14 2019-07-24 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ドナー特異的抗体を検出する方法及び該方法を実施するためのシステム
WO2015054775A1 (fr) * 2013-10-17 2015-04-23 Transfert Plus, S.E.C. Électrodes, détecteurs, leurs utilisations et leurs procédés de fabrication
US10344320B2 (en) * 2015-05-06 2019-07-09 The Johns Hopkins University Capacitive liquid crystal biosensors
US10527613B2 (en) 2015-11-10 2020-01-07 The Board Of Trustees Of The Leland Stanford Junior University Biomarker detection methods and systems and kits for practicing same
US10890578B2 (en) * 2015-12-10 2021-01-12 Wisconsin Alumni Research Foundation Using liquid crystal to detect endotoxin in the presence of one or more potential masking agents
US9921442B2 (en) * 2016-01-14 2018-03-20 Omnivision Technologies, Inc. Method for forming an alignment layer of a liquid crystal display device and display device manufactured thereby
CN106501500B (zh) * 2016-09-14 2019-03-01 北京化工大学 一种可视化检测蛋白质生物标志物的液晶传感器及其检测方法
US10175547B2 (en) 2017-04-04 2019-01-08 University Of Central Florida Research Foundation, Inc. Dynamically tunable, single pixel full-color plasmonic display, method and applications
CN106947833A (zh) * 2017-04-05 2017-07-14 天津市动物疫病预防控制中心 鸡贫血病毒lamp‑lfd检测试剂盒及其检测方法与应用
WO2019046712A1 (fr) 2017-09-01 2019-03-07 3M Innovative Properties Company Procédé de test d'ajustement pour respirateur avec un système de détection
EP3675730A1 (fr) 2017-09-01 2020-07-08 3M Innovative Properties Company Système de détection pour respirateur
CN111050858B (zh) 2017-09-01 2021-09-28 3M创新有限公司 用于具有感测***的呼吸器的贴合测试方法
WO2019043580A1 (fr) * 2017-09-01 2019-03-07 3M Innovative Properties Company Élément de détection pour respirateur
CN107748160B (zh) * 2017-09-21 2020-06-02 中山大学 一种poct即用型微流控芯片及应用方法
CN109060666A (zh) * 2018-08-27 2018-12-21 陕西科技大学 一种基于纳米金信号放大检测天蚕素b的方法
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CN113252852B (zh) * 2021-06-04 2021-10-22 金科环境股份有限公司 絮凝剂性能评价与检验设备及方法
CN113866125B (zh) * 2021-09-29 2022-05-17 之江实验室 一种利用液晶传感器实现气体特异性定量检测的方法
CN114199807B (zh) * 2021-12-10 2023-09-22 南京大学 用afm-ir检测聚酰亚胺表面分子链取向结构的方法

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US6284197B1 (en) * 1998-06-05 2001-09-04 The Regents Of The University Of California Optical amplification of molecular interactions using liquid crystals
US20030032046A1 (en) * 2000-11-08 2003-02-13 David Duffy Peelable and resealable devices for biochemical assays

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US7666661B2 (en) * 2001-08-27 2010-02-23 Platypus Technologies, Llc Substrates, devices, and methods for quantitative liquid crystal assays
WO2004041061A2 (fr) * 2002-05-22 2004-05-21 Platypus Technologies, Llc Substrats, dispositifs et procedes d'analyses cellulaires
EP1654390B1 (fr) * 2003-07-25 2009-11-11 Platypus Technologies, LLC Detection d'analyte a base de cristaux liquides

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US6284197B1 (en) * 1998-06-05 2001-09-04 The Regents Of The University Of California Optical amplification of molecular interactions using liquid crystals
US20030032046A1 (en) * 2000-11-08 2003-02-13 David Duffy Peelable and resealable devices for biochemical assays

Non-Patent Citations (1)

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Title
See also references of EP1888781A4 *

Also Published As

Publication number Publication date
EP1888781A4 (fr) 2009-01-21
EP1888781A2 (fr) 2008-02-20
WO2006121799A2 (fr) 2006-11-16
AU2006244486A1 (en) 2006-11-16
US20070042505A1 (en) 2007-02-22
CA2606916A1 (fr) 2006-11-16

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