WO2006111641A3 - Dispositif et procede d'analyse multiparametrique d'elements microscopiques - Google Patents
Dispositif et procede d'analyse multiparametrique d'elements microscopiques Download PDFInfo
- Publication number
- WO2006111641A3 WO2006111641A3 PCT/FR2006/000819 FR2006000819W WO2006111641A3 WO 2006111641 A3 WO2006111641 A3 WO 2006111641A3 FR 2006000819 W FR2006000819 W FR 2006000819W WO 2006111641 A3 WO2006111641 A3 WO 2006111641A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- rays
- measuring space
- microscopic elements
- interacting
- analyzing
- Prior art date
Links
- 238000001914 filtration Methods 0.000 abstract 2
- 238000009792 diffusion process Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1493—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6419—Excitation at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06743693A EP1875197A2 (fr) | 2005-04-21 | 2006-04-14 | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
CN2006800208234A CN101194159B (zh) | 2005-04-21 | 2006-04-14 | 微观元素多参数分析设备和方法 |
US11/912,055 US7777869B2 (en) | 2005-04-21 | 2006-04-14 | Device and method for multiparametric analysis of microscopic elements |
JP2008507118A JP2008537136A (ja) | 2005-04-21 | 2006-04-14 | 微視的要素のマルチパラメトリック分析のための装置及び方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0504005 | 2005-04-21 | ||
FR0504005A FR2884920B1 (fr) | 2005-04-21 | 2005-04-21 | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006111641A2 WO2006111641A2 (fr) | 2006-10-26 |
WO2006111641A3 true WO2006111641A3 (fr) | 2007-01-04 |
Family
ID=34955254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2006/000819 WO2006111641A2 (fr) | 2005-04-21 | 2006-04-14 | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
Country Status (7)
Country | Link |
---|---|
US (1) | US7777869B2 (fr) |
EP (1) | EP1875197A2 (fr) |
JP (1) | JP2008537136A (fr) |
KR (1) | KR20080007473A (fr) |
CN (1) | CN101194159B (fr) |
FR (1) | FR2884920B1 (fr) |
WO (1) | WO2006111641A2 (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010111514A1 (fr) * | 2009-03-25 | 2010-09-30 | Los Alamos National Security, Llc | Détection ante-mortem rapide d'agents infectieux |
CN102362179A (zh) * | 2009-03-25 | 2012-02-22 | 洛斯阿拉莫斯国家安全有限责任公司 | 用于荧光光谱测定的光纤光学组件 |
FR2956207B1 (fr) * | 2010-02-10 | 2012-05-04 | Horiba Abx Sas | Dispositif et procede de mesures multiparametriques de microparticules dans un fluide |
US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
FR2971337B1 (fr) * | 2011-02-04 | 2013-03-01 | Horiba Abx Sas | Dispositif et procede de mesures multiparametriques de microparticules dans un fluide |
GB2492950A (en) * | 2011-07-11 | 2013-01-23 | Cambridge Consultants | Measuring a luminescent property of a sample using a dual-modulated excitation beam |
CA2853093C (fr) * | 2011-10-21 | 2020-01-14 | Acea Biosciences, Inc. | Systeme et procede permettant de detecter une lumiere induite par plusieurs sources d'excitation dans un canal de circulation |
CN104169719B (zh) | 2011-12-29 | 2017-03-08 | 思迪赛特诊断有限公司 | 用于检测生物样品中病原体的方法和*** |
EP2999988A4 (fr) | 2013-05-23 | 2017-01-11 | S.D. Sight Diagnostics Ltd. | Procédé et système d'imagerie de prélèvement cellulaire |
IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for obtaining a monolayer of cells, for use specifically for diagnosis |
WO2015029032A1 (fr) | 2013-08-26 | 2015-03-05 | Parasight Ltd. | Systèmes, procédés et produits programmes d'ordinateur de microscopie numérique |
US10261080B2 (en) | 2013-11-19 | 2019-04-16 | Acea Biosciences, Inc. | Optical detection system for flow cytometer, flow cytometer system and methods of use |
EP3071951B1 (fr) | 2013-11-19 | 2019-10-30 | ACEA Biosciences, Inc. | Moteur optique pour cytomètre en flux, système de cytomètre en flux et procédés d'utilisation |
AU2015223493A1 (en) * | 2014-02-28 | 2016-10-27 | Life Technologies Corporation | Systems, methods, and apparatuses for optical systems in flow cytometers |
US9869628B2 (en) | 2014-06-25 | 2018-01-16 | Acea Biosciences, Inc. | Methods of collecting cells from multi-well plates for use in flow cytometry |
CN107077732B (zh) | 2014-08-27 | 2020-11-24 | 思迪赛特诊断有限公司 | 用于对数字显微镜计算聚焦变化的***及方法 |
JP6352750B2 (ja) * | 2014-09-26 | 2018-07-04 | シスメックス株式会社 | 血液分析装置および血液分析方法 |
JP6370659B2 (ja) * | 2014-09-26 | 2018-08-08 | シスメックス株式会社 | 血液分析装置および血液分析方法 |
EP3859425B1 (fr) | 2015-09-17 | 2024-04-17 | S.D. Sight Diagnostics Ltd. | Méthodes et appareil de détection d'entité dans un échantillon corporel |
CA3018536A1 (fr) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinction entre les composants d'un echantillon de sang |
EP3455610B1 (fr) | 2016-05-11 | 2023-01-04 | S.D. Sight Diagnostics Ltd. | Porte-échantillon pour mesures optiques |
AU2017263807B2 (en) | 2016-05-11 | 2023-02-02 | S.D. Sight Diagnostics Ltd | Performing optical measurements on a sample |
US10990797B2 (en) | 2016-06-13 | 2021-04-27 | Nanolive Sa | Method of characterizing and imaging microscopic objects |
CN109964133A (zh) * | 2016-10-31 | 2019-07-02 | 惠普发展公司,有限责任合伙企业 | 同位素的电参数 |
USD869676S1 (en) | 2017-03-28 | 2019-12-10 | Becton, Dickinson And Company | Particle sorting module |
USD868991S1 (en) | 2017-03-28 | 2019-12-03 | Becton, Dickinson And Company | Register block |
EP3710810B1 (fr) | 2017-11-14 | 2023-09-06 | S.D. Sight Diagnostics Ltd. | Porte-échantillon pour mesures optiques |
EP3514600A1 (fr) * | 2018-01-19 | 2019-07-24 | Leica Instruments (Singapore) Pte. Ltd. | Procédé de normalisation d'intensité de fluorescence |
USD876668S1 (en) | 2018-01-30 | 2020-02-25 | Becton, Dickinson And Company | Particle sorting module mount |
USD864415S1 (en) | 2018-01-30 | 2019-10-22 | Becton, Dickinson And Company | Particle sorting system |
USD872296S1 (en) | 2018-01-30 | 2020-01-07 | Becton, Dickinson And Company | Particle sorting module |
USD882817S1 (en) | 2018-01-30 | 2020-04-28 | Becton, Dickinson And Company | Sample container |
DE102018114697B4 (de) * | 2018-06-19 | 2023-02-16 | Krohne Messtechnik Gmbh | Messvorrichtung und Verfahren zur zeitaufgelösten Messung eines Messsignals |
KR102122020B1 (ko) * | 2018-09-04 | 2020-06-12 | 경북대학교 산학협력단 | 혈구 분석 장치, 이를 이용한 혈구 분석 방법 |
US20210396642A1 (en) * | 2020-06-18 | 2021-12-23 | Wyatt Technology Corporation | Calculating molar mass values of components of and molar mass concentration values of conjugate molecules/particles |
KR102435974B1 (ko) * | 2020-09-28 | 2022-08-24 | (주)티에스테크 | 멀티 측정모듈을 이용한 미세먼지 측정 장치 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4735504A (en) * | 1983-10-31 | 1988-04-05 | Technicon Instruments Corporation | Method and apparatus for determining the volume & index of refraction of particles |
WO1992008120A1 (fr) * | 1990-10-29 | 1992-05-14 | Macquarie University | Cytometrie en flux a laser impulsionnel |
US5270548A (en) * | 1992-07-31 | 1993-12-14 | The United States Of America As Represented By The United States Department Of Energy | Phase-sensitive flow cytometer |
US20030205682A1 (en) * | 2002-05-03 | 2003-11-06 | Rakesh Kapoor | Evaluation of multicomponent mixtures using modulated light beams |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4573796A (en) * | 1984-01-06 | 1986-03-04 | The United States Of America As Represented By The United States Department Of Energy | Apparatus for eliminating background interference in fluorescence measurements |
US5303026A (en) * | 1991-02-26 | 1994-04-12 | The Regents Of The University Of California Los Alamos National Laboratory | Apparatus and method for spectroscopic analysis of scattering media |
DE69333502T2 (de) * | 1992-09-14 | 2005-04-14 | Sri International, Menlo Park | Up-converting Reporter-Molekül für biologische und andere Testverfahren unter Verwendung von Laseranregungstechniken |
JPH06186155A (ja) * | 1992-10-21 | 1994-07-08 | Toa Medical Electronics Co Ltd | 粒子分析装置 |
US5418371A (en) * | 1993-02-01 | 1995-05-23 | Aslund; Nils R. D. | Apparatus for quantitative imaging of multiple fluorophores using dual detectors |
US5986271A (en) * | 1997-07-03 | 1999-11-16 | Lazarev; Victor | Fluorescence imaging system |
US20070096039A1 (en) * | 2002-05-03 | 2007-05-03 | Rakesh Kapoor | Evaluation Of Multicomponent Mixtures Using Modulated Light Beams |
JP4598766B2 (ja) * | 2003-04-29 | 2010-12-15 | エス3アイ, エル エル シィ | 生物学的微粒子及び非生物学的微粒子を検出し且つ分類するためのマルチスペクトル光学方法及びシステム |
-
2005
- 2005-04-21 FR FR0504005A patent/FR2884920B1/fr not_active Expired - Fee Related
-
2006
- 2006-04-14 US US11/912,055 patent/US7777869B2/en not_active Expired - Fee Related
- 2006-04-14 EP EP06743693A patent/EP1875197A2/fr not_active Withdrawn
- 2006-04-14 CN CN2006800208234A patent/CN101194159B/zh not_active Expired - Fee Related
- 2006-04-14 JP JP2008507118A patent/JP2008537136A/ja active Pending
- 2006-04-14 KR KR1020077027024A patent/KR20080007473A/ko not_active Application Discontinuation
- 2006-04-14 WO PCT/FR2006/000819 patent/WO2006111641A2/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4735504A (en) * | 1983-10-31 | 1988-04-05 | Technicon Instruments Corporation | Method and apparatus for determining the volume & index of refraction of particles |
WO1992008120A1 (fr) * | 1990-10-29 | 1992-05-14 | Macquarie University | Cytometrie en flux a laser impulsionnel |
US5270548A (en) * | 1992-07-31 | 1993-12-14 | The United States Of America As Represented By The United States Department Of Energy | Phase-sensitive flow cytometer |
US20030205682A1 (en) * | 2002-05-03 | 2003-11-06 | Rakesh Kapoor | Evaluation of multicomponent mixtures using modulated light beams |
Non-Patent Citations (1)
Title |
---|
SHAPIRO H M ET AL: "COMBINED BLOOD CELL COUNTING AND CLASSIFICATION WITH FLUOROCHROME STAINS AND FLOW INSTRUMENTATION", JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, HISTOCHEMICAL SOCIETY, NEW YORK, NY, US, vol. 24, no. 1, January 1976 (1976-01-01), pages 396 - 411, XP002058391, ISSN: 0022-1554 * |
Also Published As
Publication number | Publication date |
---|---|
FR2884920A1 (fr) | 2006-10-27 |
CN101194159B (zh) | 2012-05-02 |
US20080283754A1 (en) | 2008-11-20 |
FR2884920B1 (fr) | 2007-08-10 |
WO2006111641A2 (fr) | 2006-10-26 |
CN101194159A (zh) | 2008-06-04 |
JP2008537136A (ja) | 2008-09-11 |
EP1875197A2 (fr) | 2008-01-09 |
US7777869B2 (en) | 2010-08-17 |
KR20080007473A (ko) | 2008-01-21 |
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