WO2006050031A3 - Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur - Google Patents

Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur Download PDF

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Publication number
WO2006050031A3
WO2006050031A3 PCT/US2005/038784 US2005038784W WO2006050031A3 WO 2006050031 A3 WO2006050031 A3 WO 2006050031A3 US 2005038784 W US2005038784 W US 2005038784W WO 2006050031 A3 WO2006050031 A3 WO 2006050031A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
biological membrane
electrode assembly
medium
based hydrogel
Prior art date
Application number
PCT/US2005/038784
Other languages
English (en)
Other versions
WO2006050031A9 (fr
WO2006050031A2 (fr
Inventor
Han Chuang
Original Assignee
Sontra Medical Corp
Han Chuang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/223,957 external-priority patent/US20060094944A1/en
Application filed by Sontra Medical Corp, Han Chuang filed Critical Sontra Medical Corp
Publication of WO2006050031A2 publication Critical patent/WO2006050031A2/fr
Publication of WO2006050031A9 publication Critical patent/WO2006050031A9/fr
Publication of WO2006050031A3 publication Critical patent/WO2006050031A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150083—Means for enhancing collection by vibration, e.g. ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B2010/0003—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Pain & Pain Management (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un système de contrôle d'analyte transdermique comprenant un milieu conçu pour faire l'interface avec une membrane biologique et pour recevoir un analyte de cette membrane biologique, et un ensemble électrodes comprenant une pluralité d'électrodes. Le milieu est conçu pour réagir en continu avec l'analyte. Un signal électrique est détecté par l'ensemble électrodes, et ce signal est corrélé à une valeur d'analyte. Cette valeur peut représenter le flux d'analyte à travers la membrane biologique ou la concentration d'analyte dans un liquide organique du patient. Le milieu peut comprendre un hydrogel à base d'acétate de vinyle, un hydrogel à base d'agarose ou un hydrogel à base de diacrylate de polyéthylène glycol (PEG-DA), par exemple. La zone de surface de l'électrode peut contenir du platine pur. Le système selon l'invention peut comprendre un filtre interférentiel placé entre la membrane biologique et l'ensemble électrodes pour réduire l'interférence dans le système. Ledit système peut également comprendre un processeur programmé pour mettre en oeuvre un procédé de correction d'erreur qui corrige les dérives de capteurs.
PCT/US2005/038784 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur WO2006050031A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US97496304A 2004-10-28 2004-10-28
US10/974,963 2004-10-28
US20133405A 2005-08-11 2005-08-11
US11/201,334 2005-08-11
US11/223,957 US20060094944A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with error correction
US11/223,960 US20060094945A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis
US11/223,957 2005-09-13
US11/223,971 US8224414B2 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with hydrogel

Publications (3)

Publication Number Publication Date
WO2006050031A2 WO2006050031A2 (fr) 2006-05-11
WO2006050031A9 WO2006050031A9 (fr) 2006-06-15
WO2006050031A3 true WO2006050031A3 (fr) 2007-05-18

Family

ID=38441686

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2005/038785 WO2006050032A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel
PCT/US2005/038784 WO2006050031A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur
PCT/US2005/038786 WO2006050033A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2005/038785 WO2006050032A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2005/038786 WO2006050033A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse

Country Status (4)

Country Link
EP (1) EP1819283A4 (fr)
AU (1) AU2005302584B2 (fr)
CA (1) CA2584699C (fr)
WO (3) WO2006050032A2 (fr)

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RU2008130870A (ru) * 2005-12-27 2010-02-10 Байер Хэлткэр Ллк (Us) Система электрохимического датчика, использующая подложку с, по меньшей мере, одним отверстием, и способ ее изготовления
JP5234967B2 (ja) 2006-02-27 2013-07-10 エドワーズ ライフサイエンシーズ コーポレイション 静脈内電流測定バイオセンサのための流束制限膜
JP5508861B2 (ja) * 2007-03-07 2014-06-04 エコー セラピューティクス， インコーポレイテッド 経皮的被検体モニタリングシステム
CN105380662B (zh) * 2008-07-31 2018-06-12 希森美康株式会社 用于测定活体内成分的方法、装置及收集部件
WO2010027471A2 (fr) 2008-09-04 2010-03-11 The General Hospital Corporation Hydrogels pour l'augmentation et la réparation des cordes vocales et de tissu mou
WO2010061386A2 (fr) * 2008-11-25 2010-06-03 B.G. Negev Technologies And Applications Ltd. Composition pharmaceutique et système pour la perméabilisation de membranes foetales
EP2208458A1 (fr) * 2009-01-14 2010-07-21 Roche Diagnostics GmbH Réseau de surveillance médical
US9119578B2 (en) 2011-04-29 2015-09-01 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
EP3566649B1 (fr) 2009-03-02 2023-06-07 YourBio Health, Inc. Dispositifs de prélèvement de sang
WO2011109730A2 (fr) 2010-03-04 2011-09-09 The General Hospital Corporation Procédés et systèmes de compensation des déficiences vocales au moyen d'un implant de muqueuse adaptable permettant de rétablir et renforcer la production sonore et vocale humaine individualisée
US20120006100A1 (en) 2010-07-06 2012-01-12 Medtronic Minimed, Inc. Method and/or system for determining blood glucose reference sample times
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149155A1 (fr) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systèmes et procédés pour collecter un fluide d'un sujet
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
US9968284B2 (en) * 2011-12-02 2018-05-15 Clinitech, Llc Anti-interferent barrier layers for non-invasive transdermal sampling and analysis device
US10371610B2 (en) 2016-02-23 2019-08-06 Noul Co., Ltd. Contact-type patch, staining method using the same, and manufacturing method thereof
KR20170099739A (ko) 2016-02-23 2017-09-01 노을 주식회사 접촉식 염색 보조 패치, 그 제조 방법 및 이를 이용하는 염색 방법
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay

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Also Published As

Publication number Publication date
WO2006050032A2 (fr) 2006-05-11
EP1819283A4 (fr) 2011-08-10
EP1819283A2 (fr) 2007-08-22
CA2584699C (fr) 2015-12-08
AU2005302584B2 (en) 2011-08-11
CA2584699A1 (fr) 2006-05-11
AU2005302584A1 (en) 2006-05-11
WO2006050033A3 (fr) 2006-11-02
WO2006050032A9 (fr) 2006-11-02
WO2006050032A3 (fr) 2006-09-08
WO2006050033A2 (fr) 2006-05-11
WO2006050031A9 (fr) 2006-06-15
WO2006050031A2 (fr) 2006-05-11
WO2006050033B1 (fr) 2006-12-14
WO2006050033A9 (fr) 2007-02-01

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