WO2005074699A3 - Verfahren zur herstellung fester dispersionen - Google Patents

Verfahren zur herstellung fester dispersionen Download PDF

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Publication number
WO2005074699A3
WO2005074699A3 PCT/AT2005/000039 AT2005000039W WO2005074699A3 WO 2005074699 A3 WO2005074699 A3 WO 2005074699A3 AT 2005000039 W AT2005000039 W AT 2005000039W WO 2005074699 A3 WO2005074699 A3 WO 2005074699A3
Authority
WO
WIPO (PCT)
Prior art keywords
sugar
production
solid dispersions
extruder
mixtures
Prior art date
Application number
PCT/AT2005/000039
Other languages
English (en)
French (fr)
Other versions
WO2005074699A2 (de
Inventor
Thomas Tritthart
Original Assignee
Thomas Tritthart
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Tritthart filed Critical Thomas Tritthart
Publication of WO2005074699A2 publication Critical patent/WO2005074699A2/de
Publication of WO2005074699A3 publication Critical patent/WO2005074699A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/12—Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/72—Encapsulation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/20—Extruding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Colloid Chemistry (AREA)

Abstract

Beschrieben wird ein Verfahren zur Einkapselung von Substanzen in einer Matrix, enthaltend Zucker, Zuckeralkohole, Zuckerersatzstoffe oder Mischungen davon, mittels Extrusion durch einen Extruder mit einer oder mehreren Temperaturzonen, welches dadurch gekennzeichnet ist, dass die Matrix mit den zu verkapselnden Substanzen bei einer Temperatur extrudiert werden, bei der die Zucker, Zuckeralkohole, Zuckerersatzstoffe oder Mischungen davon den Extruder in teilweise geschmolzenem Zustand verlassen.
PCT/AT2005/000039 2004-02-04 2005-02-04 Verfahren zur herstellung fester dispersionen WO2005074699A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0015804A AT500101A1 (de) 2004-02-04 2004-02-04 Verkapselungsprozess
ATA158/2004 2004-02-04

Publications (2)

Publication Number Publication Date
WO2005074699A2 WO2005074699A2 (de) 2005-08-18
WO2005074699A3 true WO2005074699A3 (de) 2005-10-06

Family

ID=34831624

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT2005/000039 WO2005074699A2 (de) 2004-02-04 2005-02-04 Verfahren zur herstellung fester dispersionen

Country Status (2)

Country Link
AT (1) AT500101A1 (de)
WO (1) WO2005074699A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1969953A1 (de) * 2007-03-13 2008-09-17 Friesland Brands B.V. Allergenfreie, proteinfreie oder zumindest milchfreie pulverförmige Nährstoffzusammensetzungen und deren Verwendung in Nahrungsmitteln
FR3007290B1 (fr) * 2013-06-25 2015-06-26 Expressions Aromatiques Procede de fabrication de granules contenant un principe actif, a dluo et charge en principe actif optimisees
DE102014104676A1 (de) 2014-04-02 2015-10-08 Heraeus Medical Gmbh Fosfomycin-Zubereitung, ein Verfahren zur Herstellung der Zubereitung und ein die Zubereitung enthaltendes Polymethylmethacrylat-Knochenzementpulver
CN114041519A (zh) * 2021-11-25 2022-02-15 浙江华康药业股份有限公司 一种制备可直接压片木糖醇颗粒的方法
CN114601142B (zh) * 2022-03-31 2023-12-22 鲜之然(天津)生物技术有限公司 猪骨调味粉的制作方法和应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0435450A2 (de) * 1989-11-22 1991-07-03 SPI POLYOLS, Inc. Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol
US5370881A (en) * 1987-04-20 1994-12-06 Fuisz Technologies Ltd. Water-soluble delivery systems for hydrophobic liquids
US5472733A (en) * 1994-11-14 1995-12-05 Warner-Lambert Company Dry extrusion cooking of sugar or sugarless products
US5679398A (en) * 1990-12-14 1997-10-21 Roquette Freres Partially melt co-crystallized xylitol/sorbitol and a process for obtaining the same
WO2000025606A1 (en) * 1998-11-04 2000-05-11 Firmenich Sa Solid delivery systems for aroma ingredients
EP1013176A1 (de) * 1998-12-22 2000-06-28 Gergely, Gerhard Zucker- und/oder zuckeralkoholhältiges Matrixmaterial und Verfahren zu seiner Herstellung
WO2001080822A2 (en) * 2000-04-20 2001-11-01 Ethypharm Effervescent granules and methods for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178850A (en) * 1988-06-30 1993-01-12 Ici Americas Inc. Crystalline sugar alcohol containing uniformly dispersed liquid pharmaceutical compound

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370881A (en) * 1987-04-20 1994-12-06 Fuisz Technologies Ltd. Water-soluble delivery systems for hydrophobic liquids
EP0435450A2 (de) * 1989-11-22 1991-07-03 SPI POLYOLS, Inc. Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol
US5679398A (en) * 1990-12-14 1997-10-21 Roquette Freres Partially melt co-crystallized xylitol/sorbitol and a process for obtaining the same
US5472733A (en) * 1994-11-14 1995-12-05 Warner-Lambert Company Dry extrusion cooking of sugar or sugarless products
WO2000025606A1 (en) * 1998-11-04 2000-05-11 Firmenich Sa Solid delivery systems for aroma ingredients
EP1013176A1 (de) * 1998-12-22 2000-06-28 Gergely, Gerhard Zucker- und/oder zuckeralkoholhältiges Matrixmaterial und Verfahren zu seiner Herstellung
WO2001080822A2 (en) * 2000-04-20 2001-11-01 Ethypharm Effervescent granules and methods for their preparation

Also Published As

Publication number Publication date
WO2005074699A2 (de) 2005-08-18
AT500101A1 (de) 2005-10-15

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