WO2005044824A3 - Processes for the preparation of highly pure 3-(2-substituted vinyl) cephalosporin - Google Patents
Processes for the preparation of highly pure 3-(2-substituted vinyl) cephalosporin Download PDFInfo
- Publication number
- WO2005044824A3 WO2005044824A3 PCT/IB2004/003571 IB2004003571W WO2005044824A3 WO 2005044824 A3 WO2005044824 A3 WO 2005044824A3 IB 2004003571 W IB2004003571 W IB 2004003571W WO 2005044824 A3 WO2005044824 A3 WO 2005044824A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- highly pure
- preparation
- cephalosporin
- processes
- substituted vinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006538976A JP2007510709A (en) | 2003-11-07 | 2004-11-01 | Method for producing high purity 3- (2-substituted vinyl) cephalosporin |
EP04798757A EP1689755A2 (en) | 2003-11-07 | 2004-11-01 | Processes for the preparation of highly pure 3-(2-substituted vinyl) cephalosporin |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1368/DEL/2003 | 2003-11-07 | ||
IN1368DE2003 | 2003-11-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005044824A2 WO2005044824A2 (en) | 2005-05-19 |
WO2005044824A3 true WO2005044824A3 (en) | 2005-07-14 |
Family
ID=34566866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2004/003571 WO2005044824A2 (en) | 2003-11-07 | 2004-11-01 | Processes for the preparation of highly pure 3-(2-substituted vinyl) cephalosporin |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1689755A2 (en) |
JP (1) | JP2007510709A (en) |
CN (1) | CN1902207A (en) |
AR (1) | AR046229A1 (en) |
WO (1) | WO2005044824A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7459550B2 (en) | 2003-07-04 | 2008-12-02 | Orchid Chemicals & Pharmaceuticals Ltd. | Process for the preparation of Cefditoren |
WO2006024900A1 (en) * | 2004-08-31 | 2006-03-09 | Ranbaxy Laboratories Limited | Highly pure cefditoren pivoxil |
US20090111997A1 (en) * | 2005-11-23 | 2009-04-30 | Aaron Cote | Method of Generating Amorphous Solid for Water-Insoluble Pharmaceuticals |
CN101560216B (en) * | 2009-05-27 | 2011-06-15 | 上海交通大学 | Method for preparing cefditoren pivoxil |
KR101561963B1 (en) * | 2013-05-23 | 2015-10-22 | 영진약품공업 주식회사 | Novel crystalline from of cefditoren pivoxyl and preparation method thereof |
CN106117244B (en) * | 2016-06-24 | 2018-10-19 | 瑞阳制药有限公司 | The process for purification of Cefditoren pivoxil Cephalosporins |
CN106243128B (en) * | 2016-07-30 | 2018-09-04 | 济南康和医药科技有限公司 | A kind of process for purification of Cefditoren pivoxil Cephalosporins |
CN107422056B (en) * | 2017-08-17 | 2020-04-24 | 山东裕欣药业有限公司 | Gas chromatography detection method of iodomethyl pivalate and preparation method thereof |
CN109053768A (en) * | 2018-08-07 | 2018-12-21 | 中国医药集团总公司四川抗菌素工业研究所 | A kind of preparation method of unformed cefditoren |
CN109336904B (en) * | 2018-11-21 | 2020-06-09 | 山东罗欣药业集团股份有限公司 | Preparation method of cefditoren pivoxil |
CN110251467A (en) * | 2019-06-26 | 2019-09-20 | 北京济美堂医药研究有限公司 | A kind of preparation method of amorphous state Cefditoren pivoxil Cephalosporins composition |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998012200A1 (en) * | 1996-09-20 | 1998-03-26 | Meiji Seika Kaisha Ltd. | A crystalline substance of cefditoren pivoxyl and the production of the same |
EP1051978A1 (en) * | 1998-01-07 | 2000-11-15 | Meiji Seika Kaisha, Ltd. | Crystallographically stable amorphous cephalosporin compositions and process for producing the same |
JP2001131071A (en) * | 1999-10-29 | 2001-05-15 | Meiji Seika Kaisha Ltd | Amorphous substance and medical composition containing amorphous substance |
-
2004
- 2004-11-01 CN CNA2004800397561A patent/CN1902207A/en active Pending
- 2004-11-01 JP JP2006538976A patent/JP2007510709A/en not_active Withdrawn
- 2004-11-01 WO PCT/IB2004/003571 patent/WO2005044824A2/en not_active Application Discontinuation
- 2004-11-01 EP EP04798757A patent/EP1689755A2/en not_active Withdrawn
- 2004-11-05 AR ARP040104059A patent/AR046229A1/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998012200A1 (en) * | 1996-09-20 | 1998-03-26 | Meiji Seika Kaisha Ltd. | A crystalline substance of cefditoren pivoxyl and the production of the same |
US6294669B1 (en) * | 1996-09-20 | 2001-09-25 | Meiji Seika Kaisha Ltd. | Crystalline substance of cefditoren pivoxyl and the production of the same |
US20020002279A1 (en) * | 1996-09-20 | 2002-01-03 | Kiyoshi Yasui | Crystalline substance of cefditoren pivoxyl and the production of the same |
EP1051978A1 (en) * | 1998-01-07 | 2000-11-15 | Meiji Seika Kaisha, Ltd. | Crystallographically stable amorphous cephalosporin compositions and process for producing the same |
US6342493B1 (en) * | 1998-01-07 | 2002-01-29 | Meiji Seika Kaisha Ltd. | Crystallographically stable amorphous cephalosporin compositions and process for producing the same |
US20020037322A1 (en) * | 1998-01-07 | 2002-03-28 | Masahiro Onodera | Composition comprising a crystallographically stable, amorphous cephalosporin and processes for the preparation thereof |
JP2001131071A (en) * | 1999-10-29 | 2001-05-15 | Meiji Seika Kaisha Ltd | Amorphous substance and medical composition containing amorphous substance |
Also Published As
Publication number | Publication date |
---|---|
WO2005044824A2 (en) | 2005-05-19 |
AR046229A1 (en) | 2005-11-30 |
JP2007510709A (en) | 2007-04-26 |
EP1689755A2 (en) | 2006-08-16 |
CN1902207A (en) | 2007-01-24 |
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