WO2004023159A1 - ガラス線量計の線量分布読取方法およびその装置 - Google Patents
ガラス線量計の線量分布読取方法およびその装置 Download PDFInfo
- Publication number
- WO2004023159A1 WO2004023159A1 PCT/JP2002/013225 JP0213225W WO2004023159A1 WO 2004023159 A1 WO2004023159 A1 WO 2004023159A1 JP 0213225 W JP0213225 W JP 0213225W WO 2004023159 A1 WO2004023159 A1 WO 2004023159A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dose
- glass
- fluorescent
- glass element
- dosimeter
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/02—Dosimeters
- G01T1/10—Luminescent dosimeters
- G01T1/105—Read-out devices
Definitions
- the present invention is a two-dimensional camera using, t background art relate dose distributions reading method and apparatus for a glass wire meter reading secondary source or a three-dimensional dose and dose distribution of the glass dosimeter simultaneously
- a radio-mix film called a gak-ku mix
- This film does not use a photosensitizing effect like a silver halide film, but uses a discoloration effect (changes to blue) that is proportional to the amount of ionizing radiation, and is used in a dark room.
- this radiochromic film is not suitable for accurate dosimetry due to the problem that its sensitivity changes with storage temperature. Furthermore, the unit cost of the film is expensive and cannot be reused, which is economically disadvantageous.
- a glass dosimeter has been conventionally known as having high measurement accuracy and excellent cost.
- the glass dosimeter is provided with a fluorescent glass element made of phosphate glass containing silver ions.
- the fluorescent glass element When the fluorescent glass element is activated by exposure to ionizing radiation and is excited by ultraviolet light, Fluorescence is generated from a predetermined glass surface. Since the fluorescence intensity at this time is proportional to the radiation dose, the radiation dose can be obtained from the fluorescence intensity.
- the above-mentioned glass dosimeters can be reset by heat treatment, so that they can be reused and can be accurately measured even at high doses. Is considered.
- a fluorescent glass element is installed at the irradiation position of a radiotherapy device such as gamma knife or cyber knife (the position where the lesion should come during treatment). Then, irradiation may be performed to confirm whether a predetermined dose is applied to the irradiation position determined from prior examinations such as CT and MRI.
- a specific example of a conventional glass dosimeter is disclosed in Japanese Patent Application Laid-Open No. 3-102283. This is based on the radiation quality and incident direction of the personal dosimeter from the viewpoint of radiation accident analysis.
- the purpose of this study is to detect fluorescence by changing the fluorescence detection position (or area) with a diagram. The direction of incidence is estimated by using a dosimeter element with a slit (portion without a filter) in the center as shown in Fig. 26 of the same publication.
- the fluorescence intensity distribution obtained with a dosimeter with this structure is a one-dimensional distribution), and it is assumed that whole-body exposure is assumed instead of narrow beam irradiation. However, accurate dose distribution measurement is not possible.
- Japanese Patent No. 30142425 As a radiation dose reader capable of detecting a fluorescence intensity distribution, there is one disclosed in Japanese Patent No. 30142425.
- This device is used in a dose reader for estimating the direction of radiation incidence from the position of the fluorescence peak in a glass element equipped with a filter, as in Japanese Patent Application Laid-Open No. 3-102283. It uses an area sensor such as a CCD.
- the CCD camera did not provide sufficient sensitivity, so the detector was brought into close contact with the glass element (Claim 1 of the same gazette). Therefore, it is difficult to grasp a detailed fluorescence intensity distribution corresponding to a CCD pixel.
- Japanese Patent No. 3,057,168 discloses a technique for correcting fluorescence intensity fluctuation due to output fluctuation of an ultraviolet excitation light source in a fluorescent glass dosimeter measuring device using a nitrogen gas laser as a light source.
- this technology has been It relates to the correction of fluctuations in the total amount of ultraviolet light.
- the conventional glass dosimeter detects only the total amount of fluorescence intensity using a photomultiplier tube, etc.
- the three-dimensional dose distribution could not be read, and the irradiation range and radiation dose from the radiation therapy equipment could not be determined.
- a filter must be used in combination with the fluorescent glass element, and the dose distribution by narrow beam irradiation, which is the object of the present invention, cannot be read.
- the fluorescent glass element is usually in the form of a thin plate or film, it is difficult to reliably set the element on a plane including the beam concentration point. Therefore, there has been a strong demand for the development of a technology that can determine the dose and the dose distribution at the beam convergence point and the surrounding area by reading the three-dimensional dose distribution.
- An object of the present invention is to read a two-dimensional or three-dimensional dose and a dose distribution of a glass dosimeter so that it is possible to check with high accuracy whether a predetermined amount of radiation has been irradiated at a predetermined position,
- An object of the present invention is to provide a method and an apparatus for reading a dose distribution of a glass dosimeter, which contribute to improving the reliability of radiotherapy.
- a glass dosimeter that excites a fluorescent glass element irradiated with radiation with ultraviolet rays and reads a radiation dose based on the intensity of fluorescence generated from a fluorescence detection surface of the fluorescent glass element at that time.
- the radiation dose reading method according to claim 1, wherein a two-dimensional camera is used as a detector for detecting the fluorescence intensity from the fluorescent glass element.
- a fluorescence intensity measurement step for measuring the fluorescence intensity for each predetermined pixel segment comprising one or more pixels, and a step for converting the fluorescence intensity measured for each pixel segment into a dose. And outputting a dose and a dose distribution for each pixel section.
- the invention according to the first aspect is grasped from the viewpoint of an apparatus, and a fluorescent glass element which has been irradiated with radiation is excited with ultraviolet light,
- a fluorescence intensity measurement unit that measures the fluorescence intensity for each pixel segment composed of one or more pixels set in advance, a dose calculation unit that converts the fluorescence intensity measured for each pixel segment into a dose, A dose distribution output unit that outputs a dose and a dose distribution for each pixel division.
- the two-dimensional dose and the dose distribution of the glass dosimeter can be simultaneously read by using the two-dimensional force meter. Therefore, it is possible to confirm the irradiation position and irradiation amount of the radiation with high accuracy, and it is possible to enhance the reliability of the radiation treatment.
- a glass dosimeter that excites a fluorescent glass element irradiated with radiation with ultraviolet light and reads a radiation dose based on the intensity of fluorescence generated from a fluorescence detection surface of the fluorescent glass element at that time.
- the radiation dose reading method according to claim 1, wherein the fluorescent glass A two-dimensional camera is used as a detector for detecting the fluorescence intensity from the element, and the incident position of ultraviolet light is changed in the thickness direction of the fluorescent glass element from a side surface other than the fluorescence detection surface of the fluorescent glass element.
- the invention according to the second aspect is grasped from the viewpoint of an apparatus, and a fluorescent glass element which has been irradiated with radiation is excited with ultraviolet light.
- a radiation dose reading device for a glass dosimeter that reads a radiation dose based on the fluorescence intensity generated from the fluorescence detection surface of the fluorescent glass element, wherein the two-dimensional detector serves as a detector that detects the fluorescence intensity from the fluorescent glass element.
- a thin-layered ultraviolet ray is irradiated from the side surface other than the fluorescence detection surface of the fluorescent glass element in the thickness direction of the fluorescent glass element by changing the incident position of the ultraviolet ray, and the fluorescence intensity at each irradiation position is described above.
- a three-dimensional dose and a three-dimensional dose distribution of the fluorescent glass element are obtained by combining a fluorescence intensity measurement unit that measures using a two-dimensional camera and a plurality of data measured by changing the incident position of the ultraviolet light. Power And a three-dimensional data output unit that.
- the fluorescence intensity of each pixel section is measured using a two-dimensional camera, and at the same time, the ultraviolet light is incident in the thickness direction of the fluorescent glass element. Change the position By obtaining a plurality of measured values for each pixel section, it is possible to read the three-dimensional dose and dose distribution of the glass dosimeter. Therefore, it is possible to accurately understand the dose and dose distribution at the beam concentration point and its surrounding area. This makes it possible to accurately confirm the irradiation position and irradiation amount of the radiation, and to enhance the reliability of the radiation treatment.
- block glass is used as the fluorescent glass element
- the fluorescent intensity measuring step includes the step of: The layered ultraviolet light is scanned vertically on the glass block to measure the fluorescence intensity at each irradiation position.
- the fluorescent intensity measuring step includes the step of: Irradiate layered ultraviolet light to each thin glass and measure the fluorescence intensity of each thin glass.
- the three-dimensional dose and the It is possible to read the distribution.
- the incident position of the ultraviolet ray is changed by moving the fluorescent glass element.
- the invention according to the 5th aspect is captured from the viewpoint of the device, and the invention according to the 11th aspect is provided.
- the fluorescent glass element when changing the incident position of the ultraviolet ray, the fluorescent glass element is moved, so that the optical path of the exciting ultraviolet ray does not change. Therefore, it is possible to suppress the optical path from being changed over time. Further, since the fluorescence generation position does not change, there is no need to move the focal point of the two-dimensional camera, and stable measurement is possible.
- a glass dosimeter which excites a fluorescent glass element irradiated with radiation with ultraviolet light and reads a radiation dose based on the intensity of fluorescence generated from a fluorescence detection surface of the fluorescent glass element at that time.
- a radiation dose reading method wherein a two-dimensional camera is used as a detector for detecting the intensity of fluorescence from the fluorescent glass element, and a plurality of thin glass sheets stacked as the fluorescent glass element are used.
- a fluorescence intensity measurement step for measuring the fluorescence intensity for each pixel segment using the two-dimensional camera for each of the thin glass sheets, and a measurement value storage for storing the measurement value for each thin glass.
- the invention according to the sixth aspect is considered from the viewpoint of an apparatus, and in the invention according to the ninth aspect, the measurement value for each thin glass is provided.
- Measurement value storage unit that stores the measurement values, and sequentially reads or combines the stored measurement values in the stacking order Accordingly, a three-dimensional data output unit for outputting a three-dimensional dose and a three-dimensional dose distribution of the fluorescent glass element is provided.
- the fluorescence intensity of each pixel segment is measured using a two-dimensional camera, and at the same time, the measurement value of each thin glass is obtained, and the measured value is obtained.
- the three-dimensional dose and dose distribution in the glass dosimeter can be read by sequentially reading or synthesizing in the stacking order. Therefore, as in the second and eleventh inventions, it is possible to accurately grasp the dose and dose distribution at the beam concentration point and the surrounding area, and to determine the irradiation position and irradiation amount of the radiation. It can be confirmed accurately.
- by reading one thin glass at a time it is possible to read the three-dimensional dose distribution even if there is no means to change the incident position of the ultraviolet rays, so that the device can be downsized. .
- the intensity of the ultraviolet light is measured using a reference glass dosimeter in which the fluorescent glass element is uniformly irradiated with radiation. Based on the UV intensity distribution measurement step for reading the distribution and the UV intensity distribution obtained from the reference glass dosimeter, the dose and the dose distribution for each pixel section of the glass dosimeter to be measured Includes a first compensation step to compensate for
- the invention according to the seventh aspect is viewed from the viewpoint of a device, and in any one of the ninth to twelve aspects, A reference glass dosimeter that uniformly irradiates the fluorescent glass element with radiation; and a measuring object based on the intensity distribution of ultraviolet light obtained from the reference glass dosimeter. It has a correction unit that corrects the dose and dose distribution for each pixel section of the glass dosimeter.
- the intensity distribution of the ultraviolet light as the excitation light is obtained, and the dose and the dose for each pixel section of the glass dosimeter to be measured are determined based on the intensity distribution. Dose distribution is corrected. Therefore, the influence of the ultraviolet intensity distribution can be reliably excluded from each pixel section, and more accurate fluorescence intensity measurement is possible. Therefore, the dose and the dose distribution for each pixel section can be read with high accuracy, and the reliability is further improved.
- a time variation detecting step for detecting a time variation of the intensity of the ultraviolet light is detected.
- the method includes a second correction step for removing the influence of the time variation from the dose and the dose distribution for each pixel section.
- the invention according to the eighth aspect is considered from the viewpoint of an apparatus, and in any one of the ninth to thirteenth aspects, the intensity of the ultraviolet light is A time fluctuation detecting unit for detecting a time fluctuation is provided, and a second correction unit for removing an influence of the time fluctuation detected by the time fluctuation detecting unit from a dose and a dose distribution for each pixel section is provided. .
- the time variation of the intensity of the ultraviolet excitation light is obtained, and the dose and dose distribution for each pixel section of the glass dosimeter are determined so as to eliminate the influence. Is corrected. Therefore, as in the seventh and thirteenth inventions, each pixel Measurement accuracy of dose and dose distribution for each category can be improved.
- FIG. 1 is a diagram showing an apparatus configuration of a first embodiment according to the present invention.
- FIG. 2 is a functional block diagram illustrating a configuration of the image processing apparatus according to the first embodiment.
- FIG. 3 is a diagram showing a device configuration according to the second embodiment of the present invention.
- FIG. 4 is a functional block diagram illustrating a configuration of the image processing apparatus according to the second embodiment.
- FIG. 5 is a diagram showing an apparatus configuration of the third embodiment according to the present invention.
- FIG. 6 is a functional block diagram illustrating a configuration of the image processing apparatus according to the third embodiment.
- FIG. 7 is a configuration diagram of a main part of a fourth embodiment according to the present invention.
- FIG. 8 is a diagram showing a device configuration of a fifth embodiment according to the present invention.
- FIG. 9 is a diagram showing a sensitivity curve of a glass dosimeter according to the seventh embodiment of the present invention.
- FIG. 1 is a diagram illustrating an example of the device configuration of the present embodiment
- FIG. 2 is a functional block diagram illustrating the configuration of the image processing device of the present embodiment.
- 1 is a glass dosimeter
- 2 is an ultraviolet excitation light source
- 3 is a two-dimensional camera
- 4 is an image processing device
- 5 is a display device
- the glass dosimeter 1 has a fluorescent glass element.
- the fluorescent glass element is made of thin glass, and has a size of 30 mm x 30 mm x lmm, at most about 10 mm x 10 mm x lmm.
- a diaphragm is installed with a minimum width of 1 mm so as to mask the entire periphery of the fluorescent detection surface of the fluorescent glass element. This is to avoid that the edge portion becomes bright due to the scattered light from the edge portion of the glass element, and does not affect the measured value.
- the diaphragm doubles as an excitation mask and a fluorescence detection mask.
- a xenon flash lamp is used as the ultraviolet excitation light source 2. Since the xenon flash lamp contains light up to UV light and infrared light, a UV transmission filter (here, 33 ⁇ ⁇ ⁇ ⁇ ! ⁇ 370 nm only) is transmitted on the excitation light incident side. 2a is installed, and a filter that cuts ultraviolet light from the ultraviolet excitation light source 2 (in this case, ultraviolet light of about 380 nm or less) is placed on the fluorescence detection side, that is, the entrance of the two-dimensional camera 3. 3a and the fluorescent light from the fluorescent glass element (wavelength: about 600 to 70011111, or 3b, which is a penetrator (interference filter) that transmits only 600 nm or more.
- a UV transmission filter here, 33 ⁇ ⁇ ⁇ ⁇ ! ⁇ 370 nm only
- the purpose of the interference filter 3b is to efficiently transmit only the fluorescent light (RPL) generated from the fluorescent glass element, and the purpose of the ultraviolet cut filter 3a is to prevent interference. Used to prevent the generation of fluorescence when the filter 3b or lens is exposed to ultraviolet light.
- the excitation ultraviolet light from the ultraviolet excitation light source 2 is irradiated from the fluorescence detection surface side of the fluorescent glass element, and reading is performed by the two-dimensional camera 3 arranged in the orthogonal direction on the same surface. Have been.
- a cooled CCD camera (such as a 1344 ⁇ 1024 pixel) is used. Since this cooled CCD camera has low noise and high resolution, it can perform highly accurate distribution measurement, and is particularly suitable for measuring a high dose. This is because CCD cameras cannot be time-resolved, but when measuring high doses, the resolution is extremely small and poses no problem, so time-resolved measurement is not necessary.
- II cameras When low doses are included, II cameras (640 x 480 pixels, etc.) are used. At low doses, time-resolved measurements are needed to remove pre-dose (II cameras can be time-resolved).
- the time-resolved measurement is basically the same as the technology described in Japanese Patent Publication No. 4-772274 and Japanese Patent Publication No. 4-718144.
- the size of the fluorescent glass element is large compared to the two-dimensional force camera 3 and a detailed distribution measurement is required or when measuring a low dose, the fluorescent glass element is divided into multiple screens and read. It should be synthesized.
- the image processing device 4 is a device that measures the fluorescence intensity for each pixel section in the two-dimensional camera and performs predetermined data processing, and the display device 5 displays and outputs the dose and the dose distribution for each pixel section. Device.
- the image processing device 4 used in the present embodiment is configured as shown in FIG. That is, the image processing device 4 includes an image data receiving unit 41 for receiving image data from the two-dimensional camera 3, a data processing unit 42 for performing predetermined data processing, and a data storage unit 43. And a processing data output unit 44 for processing the processing data on the display device.
- the data processing section 42 includes a pixel section setting section 4 21 that treats a plurality of pixels as one pixel section, and a fluorescence intensity measurement section 4 22 that measures the fluorescence intensity of each pixel section.
- a dose calculation unit that calculates the dose for each pixel segment, a dose distribution creation unit that creates a two-dimensional dose distribution, and a plurality of two-dimensional data.
- a reference glass dosimeter (not shown) that has been irradiated with radiation and a glass dosimeter 1 to be measured are prepared, and each is irradiated with excitation ultraviolet light from an ultraviolet excitation light source 2. Then, the generated fluorescent light is taken into the two-dimensional camera 3, and a fluorescent image is obtained by the two-dimensional camera 3. This image data is taken into the image processing device 4, and the fluorescence intensity of each preset pixel section is measured (fluorescence intensity measurement step).
- the measurement of the fluorescence intensity is performed by exposing it to excitation light for a certain period of time (for example, about 10 seconds), receiving the fluorescence generated during that time, and performing two-dimensional measurement.
- the charge stored in camera 3 is being read.
- irradiation of excitation ultraviolet light and measurement of the fluorescence intensity on the glass fluorescent element are performed in a dark environment (in the housing constituting the dark box).
- the fluorescence intensity measured for each pixel section is converted into a dose. Specifically, the dose in each pixel section is calculated by calculating the ratio between the reference glass dosimeter that has been irradiated with radiation and the glass dosimeter 1 to be measured. Subsequently, the dose and the dose distribution for each pixel section are displayed on the display device 5 (dose distribution output step).
- the display mode of the display device 5 is as follows. There is
- Dose values at each spot of the two-dimensional distribution are not shown in a matrix form.
- noise reduction processing such as Gaussian filtering or Fast Fourier Transform (FFT) on the display.
- FFT Fast Fourier Transform
- the two-dimensional camera 3 can be used to simultaneously read the two-dimensional dose and the dose distribution of the glass dosimeter. Therefore, the irradiation position and irradiation amount of radiation can be confirmed with high accuracy, which can greatly contribute to the improvement of the reliability of radiation treatment.
- excitation ultraviolet light is irradiated from the fluorescence detection surface side of the fluorescent glass element, and reading is performed by a two-dimensional camera arranged in a direction orthogonal to the same plane. No optical system is required to maintain the structure, and the configuration can be simplified easily.
- FIG. 3 is a diagram illustrating an example of the device configuration of the present embodiment
- FIG. 4 is a functional block diagram illustrating the configuration of the image processing device 4 of the present embodiment.
- 1a is a reference glass dosimeter irradiated with radiation as a reference
- 1b is a glass dosimeter to be measured.
- the reference glass dosimeter 1 a is obtained by reference irradiation with Yo I Do ⁇ rays 137 C s on the entire fluorescent glass element.
- These glass dosimeters 1 a and 1 b are placed on a glass transport table 7.
- the glass transport table 7 moves the glass dosimeters 1 a and 1 b directly below the two-dimensional camera 3.
- a camera controller 8 is electrically connected to the two-dimensional camera 3 and the image processing device 4.
- the image processing device 4 used in the present embodiment is configured as shown in FIG.
- the data processing unit shown in Fig. 2 and the intensity distribution measuring unit 426 which measures the intensity distribution of ultraviolet light using a reference glass dosimeter which uniformly irradiates the fluorescent glass element with radiation were added.
- a first correction unit 427 is provided for correcting the dose and dose distribution for each pixel section of the glass dosimeter to be measured based on the ultraviolet intensity distribution.
- the other configuration is the same as that of the image processing apparatus shown in FIG. 2, and the description is omitted.
- the dose distribution of the glass dosimeter according to the second embodiment was read.
- the operation of the taking method and the apparatus will be described.
- the reference glass dosimeter 1a and the glass dosimeter 1 to be measured are prepared, and the glass transport table 7 is moved to irradiate the glass with the excitation ultraviolet light from the ultraviolet excitation light source 2 to each of them.
- the generated fluorescence is taken into the two-dimensional camera 3, and a fluorescence image is obtained by the two-dimensional camera 3.
- These image data are taken into the image processing device 4 and the fluorescence intensity of each pixel section is measured (fluorescence intensity measurement step).
- the intensity distribution obtained from the reference glass dosimeter 1a is the intensity distribution of the ultraviolet excitation light source 2 itself because the y-ray irradiation is uniformly performed on the entire fluorescent glass element.
- (Ultraviolet intensity distribution measurement step) To determine the ratio between the ultraviolet intensity distribution obtained from the reference glass dosimeter 1a and the distribution obtained from the measurement target glass dosimeter lb.
- the influence of the intensity distribution of the ultraviolet excitation light source 2 is determined, and the image processing device 4 corrects the dose distribution in the glass dosimeter 1b so as to remove the influence (
- the fluorescence intensity corrected for each pixel segment is converted into a dose (dose conversion step), and the reference glass dosimeter 1a and the glass dosimeter to be measured are converted.
- dose conversion step the fluorescence intensity corrected for each pixel segment is converted into a dose
- the reference glass dosimeter 1a and the glass dosimeter to be measured are converted.
- the intensity distribution of the ultraviolet excitation light source 2 is obtained using the reference glass dosimeter 1a, and based on that, Thus, the dose and the dose distribution in the glass dosimeter 1 to be measured can be corrected.
- the intensity distribution of the excitation light source 2 that affects the two-dimensional distribution measurement itself, it is possible to eliminate the variation of the excitation light in each pixel section of the glass dosimeter 1b.
- the fluorescence intensity can be measured more accurately.
- the dose and the dose distribution of the glass dosimeter 1b can be read with higher accuracy. Therefore, there is an effect that the reliability is further improved.
- the reference glass dosimeter 1a and the glass dosimeter 1b to be measured are replaced by the glass transport table 7, and one two-dimensional
- the fluorescence intensity is measured using only force meter 3. Since the two-dimensional camera 3 is expensive, adopting this configuration has the advantage of reducing the economic burden.
- the fluorescence intensity is measured by the same camera 3, the measurement can be stably performed without being affected by the difference in sensitivity between the cameras.
- the excitation light when reading the intensity distribution of the excitation light, the excitation light is not directly received by the camera, but the fluorescence from the reference glass dosimeter 1a irradiated with the reference light is received. This is intended to offset the temperature dependence of the fluorescent glass element on the generation of fluorescence.
- FIG. 5 is a diagram illustrating an example of the device configuration of the present embodiment
- FIG. 6 is a functional block diagram illustrating the configuration of the image processing device 4 of the present embodiment. (3 — 1) Device configuration
- a quartz plate 12 is placed close to the glass dosimeter 1.
- the quartz plate 12 reflects a part of the excitation ultraviolet light from the ultraviolet excitation light source 2.
- lens 1 3 faces to face with the quartz plate 1 2 lens 1 3 is installed, the lens 1 3 forces, et light portion to a high dose irradiated glass dosimeter 9 is c high dose irradiated glass dosimeter 9 that are provided to be sent
- a photodiode 10 is disposed below, and a preamplifier 11 is electrically connected to the photodiode 10. Further, the preamplifier 11 is electrically connected to the image processing device 4. These members are configured to detect a temporal change in the intensity of the ultraviolet excitation light.
- the image processing device 4 used in the present embodiment is configured as shown in FIG.
- the data processing unit shown in FIG. 2 is further provided with a time variation detecting unit 428 which detects the time variation of the ultraviolet excitation light, and the glass dose to be measured based on the time variation of the ultraviolet light.
- a second corrector 429 is provided to correct the dose and dose distribution for each pixel segment of the meter.
- the other configuration is the same as that of the image processing apparatus shown in FIG. 2, and the description is omitted.
- a reference glass dosimeter 1a which was irradiated with radiation as a reference, and a glass wire
- image data are taken into the image processing device 4 and the camera controller 8.
- the fluorescence intensity of each pixel section is measured (fluorescence intensity measurement step) (also for the glass dosimeters 1a and 1b).
- the quartz plate 7 reflects a part of the ultraviolet irradiation, and the lens 13 condenses it.
- the photo diode 10 detects the fluorescence generated by the high-dose irradiation glass dosimeter 9, and the pre-amplifier 11 converts this to an electric signal.
- the image processing device 4 captures the electric signal and the image data. At that time, the image data from the reference glass dosimeter 1a is divided by the signal from the high-dose irradiation glass dosimeter 9 when the image data of the reference glass dosimeter 1a was acquired. A time variation of the excitation light of the ultraviolet excitation light source 2 is detected. On the other hand, the image data from the glass dosimeter 1b to be measured can also be divided by the signal from the high-dose irradiated glass dosimeter 9 when the image data from the glass dosimeter 1b is acquired. Then, the time variation of the excitation light of the ultraviolet excitation light source 2 is detected (time variation detection step).
- the display unit 5 displays the dose and the dose distribution for each pixel section (dose distribution output step).
- the glass dosimeters 1a, 1a, 1a, 1b are devised so as to determine the time variation of the intensity of the ultraviolet excitation light from the ultraviolet excitation light source 2 and to eliminate the influence thereof. It is possible to correct the dose and dose distribution for each pixel segment in b. For this reason, as in the second embodiment, the measurement accuracy of the dose and the dose distribution for each pixel segment is significantly improved.
- a glass dosimeter is composed of a plurality of laminated thin glass sheets lc, and is adapted to the case where the glass dosimeter is irradiated with radiation.
- a fluorescent intensity measuring means for irradiating a layered ultraviolet ray to each thin glass and measuring the fluorescent intensity of each thin glass 1c for each pixel segment with a two-dimensional camera, and storing measured values for storing the measured values Means for sequentially reading or synthesizing the stored measurement values in the stacking order, thereby outputting a three-dimensional dose and a three-dimensional dose distribution of the glass dosimeter. It is configured to output the three-dimensional dose and three-dimensional dose distribution of the dosimeter.
- the operation and effect of the reading method and apparatus are basically the same as those of the first to third embodiments. It is like.
- thin-layer ultraviolet rays are irradiated from the side surface other than the fluorescence detection surface of the fluorescent glass element composed of a plurality of laminated thin glass plates 1c. Then, for each thin glass lc, the fluorescence intensity from the fluorescence detection surface is measured using the two-dimensional camera 3 (fluorescence intensity measurement step), and stored as data for each thin glass lc.
- the 3D dose and the 3D dose distribution of the fluorescent glass element are output by synthesizing the data obtained for each thin glass 1c (3D data output step). .
- the excitation ultraviolet rays are irradiated from the fluorescent detection surface side of the fluorescent glass element. It is also possible to do so.
- the fluorescence intensity is measured for each of the plurality of laminated thin glass plates 1c, and each data is synthesized. Accordingly, the three-dimensional dose and the dose distribution in the glass dosimeter 1 can be read. Therefore, the dose and dose distribution at the beam concentration point and the surrounding area can be accurately grasped, the irradiation position and the irradiation amount of the radiation can be confirmed accurately, and the reliability of radiation treatment can be improved.
- a block-shaped glass 1d is used as a fluorescent glass element, and a thin layer of ultraviolet light is applied to the block-shaped glass 1d.
- the irradiation position is scanned in the vertical direction, and the fluorescence intensity at each irradiation position is sequentially measured.
- a thin-layered excitation ultraviolet ray 2a is incident on the block-shaped glass 1d from the side via a slit.
- the incident position is moved up and down.
- the three-dimensional dose and the dose distribution in the glass dosimeter 1 can be read. Therefore, the dose and the dose distribution at the beam concentration point and the surrounding area can be accurately grasped, the radiation irradiation position and the radiation dose can be accurately confirmed, and the reliability of the radiation treatment can be improved.
- the sixth embodiment is the same as the fourth or fifth embodiment, except that a slide mechanism for vertically moving the fluorescent glass element is provided.
- the special feature is that the fluorescent glass element is moved by operating the slide mechanism.
- a well-known drive mechanism can be used for driving the slide mechanism, as long as the incident position of the ultraviolet excitation beam with respect to the fluorescent glass element can be changed at a predetermined pitch.
- the fluorescent glass element when changing the incident position of the ultraviolet light emitted from the ultraviolet light excitation light source 2, the fluorescent glass element is moved, so that the optical path of the excitation ultraviolet light does not move. For this reason, also c Ru can and this to suppress blurring of Ruhikariro by the aging, if there is no change in the optical path of the exciting ultraviolet ray, or the position does not change the fluorescence is generated, to move the two-dimensional camera , No need to focus. Therefore, the reading operation can be performed smoothly, and stable measurement can be performed.
- the moving direction of the fluorescent glass element may be in the left-right direction, and the moving pitch may be appropriately selected, for example, according to the thickness of the thin glass.
- the present invention relates to an I MRT
- IMRT is a radiation therapy method that can vary the irradiation dose on a given irradiation surface.
- the dose set by the treatment plan to concentrate the dose on the target volume (PTV) and keep the dose to the nearby important organs (OAR) unacceptable, and the dose actually delivered It is necessary to minimize the difference between this and the actual dose measurement 'QA.
- Films are currently used. However, although the film shows the relative distribution of dose, it is difficult to read the dose value accurately, the upper limit dose is low, and the measurement of the accumulated dose is difficult. There is a need for a system that can accurately measure the temperature. In addition, there is a problem that the irradiation dose cannot be read from the back surface with the diode type distributed dose measuring device.
- the glass dosimeter of the present invention is applied to IMRT, these problems can be solved, and the dose value and its distribution can be measured accurately.
- the IMRT also needs to know the dose to surrounding organs, the following advantages of the glass dosimeter are considered to be effective.
- the dose value at the site can be accurately measured with the distribution, not the relative distribution.
- Fig. 9 is a diagram showing a sensitivity curve of the glass dosimeter according to the present embodiment, in which the horizontal axis represents the irradiation dose (Gy), and the vertical axis represents the reading dose (Gy).
- Figure 9 shows the case where a thin plate (about 1 mm) glass dosimeter is used. It can read linearly up to about 20 Gy. At about 100 Gy, the reading sensitivity is slightly reduced, but practically sufficient measurement is possible. The sensitivity decrease in the high dose range can be corrected by knowing the sensitivity characteristics in advance.
- Films can usually measure only about 7 Gy, at most up to about 3 OGy, but using a glass dosimeter in this way can measure up to high doses of 10 OGy or more. You. In the actual treatment, irradiation of several tens of Gy is performed, and at least 50 Gy or less. What can be measured by is required.
- the additional dose can be read without annealing, and the accumulated dose can be read.
- the present invention is not limited to the above embodiment.
- Excited ultraviolet rays in the form of a thin layer may be made incident through a slot.
- the cross section of the excitation light can be regulated by the slit, the volume irradiated with the excitation light is always constant even if the thickness of the glass element is different. It is not affected by processing accuracy in the glass thickness direction.
- the excitation light When reading the intensity distribution of the excitation light source 2, the excitation light may be branched and two two-dimensional cameras may be used. In this case, the reference dosimeter and the dosimeter to be measured can be measured simultaneously. Therefore, there is an advantage that the light source 2 is not affected by time fluctuations. (It is also possible to correct the sensitivity difference between two two-dimensional cameras beforehand. ).
- the dimensions of the components can be changed as appropriate, and three to five layers of thin glass can be stacked as needed for three-dimensional distribution measurement. Layered or a 5mm block is desirable. Since the irradiation error of gamma knife and cyber knife is about 1 mm at most, it is possible to sufficiently capture the center of irradiation with this thickness. Note that when thin glass sheets are laminated, they are not bonded to each other, but are formed by embedding them in a phantom in a superposed state.
- the two-dimensional camera is used as a detector for detecting the fluorescence intensity from the fluorescent glass element. Since two-dimensional and three-dimensional doses and dose distributions can be easily read, it is possible to check with high accuracy whether a predetermined amount of radiation has been applied to a predetermined position, and thereby to perform radiation therapy. This can contribute to improved reliability.
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Molecular Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Measurement Of Radiation (AREA)
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20020807768 EP1544641A1 (en) | 2002-09-02 | 2002-12-18 | Dose distribution reading method for glass dosimeter |
JP2004534081A JP4171731B2 (ja) | 2002-09-02 | 2002-12-18 | ガラス線量計の線量分布読取方法およびその装置 |
US11/068,274 US7038220B2 (en) | 2002-09-02 | 2005-02-28 | Dose distribution reading method and reader for glass dosimeter |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002/256917 | 2002-09-02 | ||
JP2002256917 | 2002-09-02 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/068,274 Continuation US7038220B2 (en) | 2002-09-02 | 2005-02-28 | Dose distribution reading method and reader for glass dosimeter |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004023159A1 true WO2004023159A1 (ja) | 2004-03-18 |
Family
ID=31972964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/013225 WO2004023159A1 (ja) | 2002-09-02 | 2002-12-18 | ガラス線量計の線量分布読取方法およびその装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US7038220B2 (ja) |
EP (1) | EP1544641A1 (ja) |
JP (1) | JP4171731B2 (ja) |
WO (1) | WO2004023159A1 (ja) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006047009A (ja) * | 2004-08-02 | 2006-02-16 | Aarutekku Kk | 放射線の積算吸収線量を測定する方法、及び平板状蛍光ガラス線量計 |
JP2008102055A (ja) * | 2006-10-20 | 2008-05-01 | Nichiyu Giken Kogyo Co Ltd | 放射線ビームの確認に用いる放射線感応シート |
JP4431701B1 (ja) * | 2009-09-04 | 2010-03-17 | 学校法人立教学院 | 熱蛍光板状体の製造方法、熱蛍光積層体の製造方法、熱蛍光板状体、及び熱蛍光積層体 |
JP4457219B1 (ja) * | 2009-10-23 | 2010-04-28 | 学校法人立教学院 | 熱蛍光積層体、熱蛍光板状体、熱蛍光積層体の製造方法、熱蛍光板状体の製造方法、及び放射線の3次元線量分布の取得方法 |
WO2010064594A1 (ja) * | 2008-12-01 | 2010-06-10 | 学校法人立教学院 | 熱蛍光積層体、熱蛍光板状体、熱蛍光積層体の製造方法、熱蛍光板状体の製造方法、及び放射線の3次元線量分布の取得方法 |
JP2013022336A (ja) * | 2011-07-25 | 2013-02-04 | Institute Of Physical & Chemical Research | 荷電粒子によるエネルギー付与用ノズルの製造方法、エネルギー付与用ノズル、エネルギー付与装置、および荷電粒子照射強度計測システム |
JP2016061735A (ja) * | 2014-09-19 | 2016-04-25 | 株式会社柴田合成 | 放射線照射範囲検出器及び放射線照射範囲検出方法 |
JP2016125813A (ja) * | 2014-12-26 | 2016-07-11 | Agcテクノグラス株式会社 | 蛍光ガラス線量計読取装置 |
JP2016198236A (ja) * | 2015-04-09 | 2016-12-01 | 公益財団法人若狭湾エネルギー研究センター | 放射線モニタリングシステム |
WO2020036232A1 (ja) * | 2018-08-17 | 2020-02-20 | 国立大学法人群馬大学 | 放射線計測体及び放射線被曝量計測装置 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4343801B2 (ja) * | 2004-09-03 | 2009-10-14 | オリンパス株式会社 | 蛍光観察用暗箱装置、蛍光観察システムおよび蛍光観察方法 |
US7652268B2 (en) * | 2006-01-31 | 2010-01-26 | Jp Laboratories, Inc | General purpose, high accuracy dosimeter reader |
KR102324365B1 (ko) * | 2019-08-27 | 2021-11-11 | 고려대학교 산학협력단 | 플라스틱 형광판을 이용한 실시간 선량 모니터링 시스템 및 방법 |
US11965776B2 (en) | 2021-08-10 | 2024-04-23 | B/E Aerospace, Inc. | System and method for quantifying an exposure dose on surfaces |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03102284A (ja) * | 1989-09-18 | 1991-04-26 | Toshiba Glass Co Ltd | ガラス線量測定方法およびその測定装置 |
JPH0560866A (ja) * | 1991-03-06 | 1993-03-12 | Toshiba Glass Co Ltd | 蛍光ガラス線量計読取装置 |
JPH05119155A (ja) * | 1991-10-25 | 1993-05-18 | Toshiba Glass Co Ltd | ガラス線量測定装置 |
JP3014225B2 (ja) * | 1992-10-27 | 2000-02-28 | 旭テクノグラス株式会社 | 放射線量読取装置 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS505595A (ja) | 1973-05-24 | 1975-01-21 | ||
JPH03102283A (ja) | 1989-09-18 | 1991-04-26 | Toshiba Glass Co Ltd | 放射線量読取装置 |
JP3057168B2 (ja) | 1995-02-08 | 2000-06-26 | 旭テクノグラス株式会社 | 蛍光ガラス線量計測定装置 |
US6307212B1 (en) * | 1999-04-01 | 2001-10-23 | The United States Of America As Represented By The Secretary Of The Navy | High resolution imaging using optically transparent phosphors |
-
2002
- 2002-12-18 EP EP20020807768 patent/EP1544641A1/en not_active Withdrawn
- 2002-12-18 JP JP2004534081A patent/JP4171731B2/ja not_active Expired - Fee Related
- 2002-12-18 WO PCT/JP2002/013225 patent/WO2004023159A1/ja active Application Filing
-
2005
- 2005-02-28 US US11/068,274 patent/US7038220B2/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03102284A (ja) * | 1989-09-18 | 1991-04-26 | Toshiba Glass Co Ltd | ガラス線量測定方法およびその測定装置 |
JPH0560866A (ja) * | 1991-03-06 | 1993-03-12 | Toshiba Glass Co Ltd | 蛍光ガラス線量計読取装置 |
JPH05119155A (ja) * | 1991-10-25 | 1993-05-18 | Toshiba Glass Co Ltd | ガラス線量測定装置 |
JP3014225B2 (ja) * | 1992-10-27 | 2000-02-28 | 旭テクノグラス株式会社 | 放射線量読取装置 |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006047009A (ja) * | 2004-08-02 | 2006-02-16 | Aarutekku Kk | 放射線の積算吸収線量を測定する方法、及び平板状蛍光ガラス線量計 |
JP2008102055A (ja) * | 2006-10-20 | 2008-05-01 | Nichiyu Giken Kogyo Co Ltd | 放射線ビームの確認に用いる放射線感応シート |
US8704182B2 (en) | 2008-12-01 | 2014-04-22 | Rikkyo Gakuin | Thermoluminescent layered product, thermoluminescent plate, method of producing thermoluminescent layered product, method of producing thermoluminescent plate and method of acquiring three-dimensional dose distribution of radiation |
WO2010064594A1 (ja) * | 2008-12-01 | 2010-06-10 | 学校法人立教学院 | 熱蛍光積層体、熱蛍光板状体、熱蛍光積層体の製造方法、熱蛍光板状体の製造方法、及び放射線の3次元線量分布の取得方法 |
JP2011052179A (ja) * | 2009-09-04 | 2011-03-17 | Rikkyo Gakuin | 熱蛍光板状体の製造方法、熱蛍光積層体の製造方法、熱蛍光板状体、及び熱蛍光積層体 |
JP4431701B1 (ja) * | 2009-09-04 | 2010-03-17 | 学校法人立教学院 | 熱蛍光板状体の製造方法、熱蛍光積層体の製造方法、熱蛍光板状体、及び熱蛍光積層体 |
JP4457219B1 (ja) * | 2009-10-23 | 2010-04-28 | 学校法人立教学院 | 熱蛍光積層体、熱蛍光板状体、熱蛍光積層体の製造方法、熱蛍光板状体の製造方法、及び放射線の3次元線量分布の取得方法 |
JP2010127930A (ja) * | 2009-10-23 | 2010-06-10 | Rikkyo Gakuin | 熱蛍光積層体、熱蛍光板状体、熱蛍光積層体の製造方法、熱蛍光板状体の製造方法、及び放射線の3次元線量分布の取得方法 |
JP2013022336A (ja) * | 2011-07-25 | 2013-02-04 | Institute Of Physical & Chemical Research | 荷電粒子によるエネルギー付与用ノズルの製造方法、エネルギー付与用ノズル、エネルギー付与装置、および荷電粒子照射強度計測システム |
JP2016061735A (ja) * | 2014-09-19 | 2016-04-25 | 株式会社柴田合成 | 放射線照射範囲検出器及び放射線照射範囲検出方法 |
JP2016125813A (ja) * | 2014-12-26 | 2016-07-11 | Agcテクノグラス株式会社 | 蛍光ガラス線量計読取装置 |
JP2016198236A (ja) * | 2015-04-09 | 2016-12-01 | 公益財団法人若狭湾エネルギー研究センター | 放射線モニタリングシステム |
WO2020036232A1 (ja) * | 2018-08-17 | 2020-02-20 | 国立大学法人群馬大学 | 放射線計測体及び放射線被曝量計測装置 |
JPWO2020036232A1 (ja) * | 2018-08-17 | 2021-08-10 | 国立大学法人群馬大学 | 放射線計測体及び放射線被曝量計測装置 |
JP7260868B2 (ja) | 2018-08-17 | 2023-04-19 | 国立大学法人群馬大学 | 放射線計測体及び放射線被曝量計測装置 |
Also Published As
Publication number | Publication date |
---|---|
EP1544641A1 (en) | 2005-06-22 |
US20050218339A1 (en) | 2005-10-06 |
US7038220B2 (en) | 2006-05-02 |
JP4171731B2 (ja) | 2008-10-29 |
JPWO2004023159A1 (ja) | 2005-12-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7038220B2 (en) | Dose distribution reading method and reader for glass dosimeter | |
JP6955810B2 (ja) | 電離放射線ビームモニタリングシステム | |
EP1420618B1 (en) | X-Ray imaging apparatus | |
CN106030345B (zh) | X射线探测器、成像装置和校准方法 | |
JP6258916B2 (ja) | 電離放射線量の二次元分布を高い空間分解能で測定するための方法 | |
US11027152B1 (en) | Ionizing-radiation beam monitoring system | |
JPH10201750A (ja) | 放射線撮影装置 | |
Ahmed et al. | Demonstration of 2D dosimetry using Al2O3 optically stimulated luminescence films for therapeutic megavoltage x-ray and ion beams | |
Dempsey et al. | Quantitative optical densitometry with scanning‐laser film digitizers | |
EP3049826A1 (en) | Method and apparatus for radiation dosimetry utilizing fluorescent imaging with precision correction | |
Warman et al. | High-energy radiation monitoring based on radio-fluorogenic co-polymerization II: Fixed fluorescent images of collimated X-ray beams using an RFCP gel | |
JP6479772B2 (ja) | X線撮像装置及び方法 | |
CN104656120A (zh) | 校正信息生成方法以及校正信息生成装置 | |
JP5648891B2 (ja) | 放射線測定方法及び放射線測定装置 | |
JP2008194441A (ja) | 付加フィルタ及びこの付加フィルタを用いた半価層測定装置並びに半価層測定方法 | |
US20210364660A1 (en) | Multilayer scintillator detector and method for reconstructing a spatial distribution of a beam of irradiation | |
US9081101B2 (en) | Sensitive charge for passive dosimetry, dosimeter comprising such a sensitive charge and system for reading by illumination for such a sensitive charge | |
Lee et al. | Calibrating of x-ray detectors in the 8 to 111 keV energy range and their application to diagnostics on the National Ignition Facility | |
JP2007003463A (ja) | Cmr(共通モード雑音排除)概念による色素線量計の感度改善 | |
JPS63181740A (ja) | X線受像装置 | |
Winch et al. | X-ray imaging using digital cameras | |
Rosen | Advanced radiochromic film methodologies for quantitative dosimetry of small and nonstandard fields | |
WO2022098817A1 (en) | Ionizing-radiation beam monitoring system | |
CA2875075C (en) | Method and apparatus for radiation dosimetry utilizing fluorescent imaging with precision correction | |
CN113406686A (zh) | 一种离子束三维剂量分布探测装置及方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): JP US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2004534081 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 11068274 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002807768 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002807768 Country of ref document: EP |