WO2003104419A3 - Cancer-linked gene as target for chemotherapy - Google Patents

Cancer-linked gene as target for chemotherapy Download PDF

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Publication number
WO2003104419A3
WO2003104419A3 PCT/US2003/018060 US0318060W WO03104419A3 WO 2003104419 A3 WO2003104419 A3 WO 2003104419A3 US 0318060 W US0318060 W US 0318060W WO 03104419 A3 WO03104419 A3 WO 03104419A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
target
disclosed
chemotherapy
linked gene
Prior art date
Application number
PCT/US2003/018060
Other languages
French (fr)
Other versions
WO2003104419A2 (en
Inventor
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003243440A priority Critical patent/AU2003243440A1/en
Publication of WO2003104419A2 publication Critical patent/WO2003104419A2/en
Publication of WO2003104419A3 publication Critical patent/WO2003104419A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
PCT/US2003/018060 2002-06-11 2003-06-10 Cancer-linked gene as target for chemotherapy WO2003104419A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003243440A AU2003243440A1 (en) 2002-06-11 2003-06-10 Cancer-linked gene as target for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38767902P 2002-06-11 2002-06-11
US60/387,679 2002-06-11

Publications (2)

Publication Number Publication Date
WO2003104419A2 WO2003104419A2 (en) 2003-12-18
WO2003104419A3 true WO2003104419A3 (en) 2004-10-21

Family

ID=29736352

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/018060 WO2003104419A2 (en) 2002-06-11 2003-06-10 Cancer-linked gene as target for chemotherapy

Country Status (2)

Country Link
AU (1) AU2003243440A1 (en)
WO (1) WO2003104419A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007306828A (en) 2006-05-17 2007-11-29 Tokai Univ Phage-displayed single strand antibody recognizing non-reducing mannose residue

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030219382A1 (en) * 2002-03-06 2003-11-27 Young Paul E. Cancer-linked gene as target for chemotherapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030219382A1 (en) * 2002-03-06 2003-11-27 Young Paul E. Cancer-linked gene as target for chemotherapy

Also Published As

Publication number Publication date
AU2003243440A8 (en) 2003-12-22
AU2003243440A1 (en) 2003-12-22
WO2003104419A2 (en) 2003-12-18

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