WO2003104404A8 - Cancer-linked gene as target for chemotherapy - Google Patents

Cancer-linked gene as target for chemotherapy

Info

Publication number
WO2003104404A8
WO2003104404A8 PCT/US2003/017772 US0317772W WO03104404A8 WO 2003104404 A8 WO2003104404 A8 WO 2003104404A8 US 0317772 W US0317772 W US 0317772W WO 03104404 A8 WO03104404 A8 WO 03104404A8
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
disclosed
target
antibodies
chemotherapy
Prior art date
Application number
PCT/US2003/017772
Other languages
French (fr)
Other versions
WO2003104404A3 (en
WO2003104404A2 (en
Inventor
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003237414A priority Critical patent/AU2003237414A1/en
Publication of WO2003104404A2 publication Critical patent/WO2003104404A2/en
Publication of WO2003104404A8 publication Critical patent/WO2003104404A8/en
Publication of WO2003104404A3 publication Critical patent/WO2003104404A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Abstract

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences as well as the polypeptide sequences, especially for diagnosing prostate cancer.
PCT/US2003/017772 2002-06-06 2003-06-05 Cancer-linked gene as target for chemotherapy WO2003104404A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003237414A AU2003237414A1 (en) 2002-06-06 2003-06-05 Cancer-linked gene as target for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38665102P 2002-06-06 2002-06-06
US60/386,651 2002-06-06

Publications (3)

Publication Number Publication Date
WO2003104404A2 WO2003104404A2 (en) 2003-12-18
WO2003104404A8 true WO2003104404A8 (en) 2004-05-21
WO2003104404A3 WO2003104404A3 (en) 2006-04-13

Family

ID=29736194

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/017772 WO2003104404A2 (en) 2002-06-06 2003-06-05 Cancer-linked gene as target for chemotherapy

Country Status (2)

Country Link
AU (1) AU2003237414A1 (en)
WO (1) WO2003104404A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005001092A2 (en) * 2003-05-20 2005-01-06 Wyeth Compositions and methods for diagnosing and treating cancers
EP2177630A1 (en) * 2008-10-02 2010-04-21 Institut Gustave Roussy Methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329505B1 (en) * 1997-02-25 2001-12-11 Corixa Corporation Compositions and methods for therapy and diagnosis of prostate cancer

Also Published As

Publication number Publication date
AU2003237414A8 (en) 2003-12-22
AU2003237414A1 (en) 2003-12-22
WO2003104404A3 (en) 2006-04-13
WO2003104404A2 (en) 2003-12-18

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