WO2002079377A3 - Antibodies that immunospecifically bind to trail receptors - Google Patents
Antibodies that immunospecifically bind to trail receptors Download PDFInfo
- Publication number
- WO2002079377A3 WO2002079377A3 PCT/US2001/042996 US0142996W WO02079377A3 WO 2002079377 A3 WO2002079377 A3 WO 2002079377A3 US 0142996 W US0142996 W US 0142996W WO 02079377 A3 WO02079377 A3 WO 02079377A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antibodies
- immunospecifically bind
- relates
- trail receptors
- trail
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001297702A AU2001297702A1 (en) | 2000-11-08 | 2001-11-07 | Antibodies that immunospecifically bind to trail receptors |
EP01273517A EP1339426A4 (en) | 2000-11-08 | 2001-11-07 | Antibodies that immunospecifically bind to trail receptors |
CA002426710A CA2426710A1 (en) | 2000-11-08 | 2001-11-07 | Antibodies that immunospecifically bind to trail receptors |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24661200P | 2000-11-08 | 2000-11-08 | |
US60/246,612 | 2000-11-08 | ||
US24884700P | 2000-11-16 | 2000-11-16 | |
US60/248,847 | 2000-11-16 | ||
US25290400P | 2000-11-27 | 2000-11-27 | |
US60/252,904 | 2000-11-27 | ||
US29501801P | 2001-06-04 | 2001-06-04 | |
US60/295,018 | 2001-06-04 | ||
US32735901P | 2001-10-09 | 2001-10-09 | |
US60/327,359 | 2001-10-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002079377A2 WO2002079377A2 (en) | 2002-10-10 |
WO2002079377A3 true WO2002079377A3 (en) | 2003-03-13 |
Family
ID=27540243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/042996 WO2002079377A2 (en) | 2000-11-08 | 2001-11-07 | Antibodies that immunospecifically bind to trail receptors |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1339426A4 (en) |
AU (1) | AU2001297702A1 (en) |
CA (1) | CA2426710A1 (en) |
WO (1) | WO2002079377A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
AU2002256895B2 (en) | 2001-05-18 | 2008-09-18 | Kirin Beer Kabushiki Kaisha | Anti-TRAIL-R antibodies |
EP1531162A1 (en) * | 2003-11-14 | 2005-05-18 | Heinz Vollmers | Adenocarcinoma specific antibody SAM-6, and uses thereof |
US8129124B2 (en) | 2005-02-02 | 2012-03-06 | The Uab Research Foundation | Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists |
US7915245B2 (en) | 2007-02-01 | 2011-03-29 | The Board Of Regents Of The University Of Texas System | Methods and compositions of trail-death receptor agonists/activators |
CN105451767B (en) * | 2013-03-15 | 2019-10-18 | 泽恩格尼亚股份有限公司 | Multivalence and monovalent polyspecific compound and application thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763223A (en) * | 1995-06-29 | 1998-06-09 | Immunex Corporation | DNA encoding a cytokine that induces apoptosis |
WO1999012963A2 (en) * | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors: trail |
US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1012274B2 (en) * | 1997-01-28 | 2011-06-15 | Human Genome Sciences, Inc. | Death domain containing receptor 4 (dr4: death receptor 4), member of the tnf-receptor superfamily and binding to trail (ap0-2l) |
ES2368823T3 (en) * | 1998-01-26 | 2011-11-22 | Genentech, Inc. | ANTIBODIES OF DEATH RECEIVER 4 (DR4) AND USES OF THE SAME. |
PT1086138E (en) * | 1998-06-12 | 2010-01-04 | Genentech Inc | Monoclonal antibodies, cross-reactive antibodies and method for producing the same |
WO2002002641A1 (en) * | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
GB0020685D0 (en) * | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
-
2001
- 2001-11-07 EP EP01273517A patent/EP1339426A4/en not_active Withdrawn
- 2001-11-07 AU AU2001297702A patent/AU2001297702A1/en not_active Abandoned
- 2001-11-07 WO PCT/US2001/042996 patent/WO2002079377A2/en not_active Application Discontinuation
- 2001-11-07 CA CA002426710A patent/CA2426710A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763223A (en) * | 1995-06-29 | 1998-06-09 | Immunex Corporation | DNA encoding a cytokine that induces apoptosis |
US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
WO1999012963A2 (en) * | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors: trail |
Non-Patent Citations (1)
Title |
---|
See also references of EP1339426A4 * |
Also Published As
Publication number | Publication date |
---|---|
EP1339426A4 (en) | 2004-06-30 |
AU2001297702A1 (en) | 2002-10-15 |
WO2002079377A2 (en) | 2002-10-10 |
EP1339426A2 (en) | 2003-09-03 |
CA2426710A1 (en) | 2002-10-10 |
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