WO2002026996A3 - Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol - Google Patents

Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol Download PDF

Info

Publication number
WO2002026996A3
WO2002026996A3 PCT/EP2001/011012 EP0111012W WO0226996A3 WO 2002026996 A3 WO2002026996 A3 WO 2002026996A3 EP 0111012 W EP0111012 W EP 0111012W WO 0226996 A3 WO0226996 A3 WO 0226996A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
specific phospholipase
human phosphatidylinositol
regulation
reagents
Prior art date
Application number
PCT/EP2001/011012
Other languages
English (en)
Other versions
WO2002026996A2 (fr
Inventor
Zhimin Zhu
Original Assignee
Bayer Ag
Zhimin Zhu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Zhimin Zhu filed Critical Bayer Ag
Priority to AU2002210514A priority Critical patent/AU2002210514A1/en
Publication of WO2002026996A2 publication Critical patent/WO2002026996A2/fr
Publication of WO2002026996A3 publication Critical patent/WO2002026996A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des réactifs qui permettent de réguler une enzyme humaine de type phospholipase C spécifique du phosphatidylinositol ainsi que des réactifs qui se lient aux produits géniques de cette enzyme, et qui peuvent jouer un rôle dans la prévention, l'amélioration ou la correction de dysfonctionnements ou de maladies comprenant, notamment, l'asthme, le cancer, des troubles du système nerveux central, et la broncho-pneumopathie chronique obstructive.
PCT/EP2001/011012 2000-09-27 2001-09-24 Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol WO2002026996A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002210514A AU2002210514A1 (en) 2000-09-27 2001-09-24 Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23555200P 2000-09-27 2000-09-27
US60/235,552 2000-09-27

Publications (2)

Publication Number Publication Date
WO2002026996A2 WO2002026996A2 (fr) 2002-04-04
WO2002026996A3 true WO2002026996A3 (fr) 2002-09-26

Family

ID=22885960

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011012 WO2002026996A2 (fr) 2000-09-27 2001-09-24 Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol

Country Status (2)

Country Link
AU (1) AU2002210514A1 (fr)
WO (1) WO2002026996A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127206D0 (en) * 2001-11-13 2002-01-02 Univ Liverpool Treatment of inflammatory conditions
AU2003242759A1 (en) * 2002-06-26 2004-01-19 Bayer Healthcare Ag Regulation of human phospholipase c-like protein
US20100284992A1 (en) * 2006-10-02 2010-11-11 The Regents Of The University Of Colorado, A Body Corporate Phospholipase C and Method of Use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (fr) * 2000-03-31 2001-10-11 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (fr) * 2000-03-31 2001-10-11 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISSPROT [online] 1 July 1989 (1989-07-01), SUH ET AL.: "1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1) (PHOSPHOLIPASE C-DELTA-1) (PLC-III).", XP002199648, Database accession no. P10688 *
DATABASE SWISSPROT [online] 1 May 2000 (2000-05-01), KIKUNO ET AL.: "KIAA1069 Protein (Fragment)", XP002199647, Database accession no. Q9UPT3 *
KIKUNO ET AL.: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.", DNA RESEARCH, vol. 6, 1999, pages 197 - 205, XP000852618 *

Also Published As

Publication number Publication date
AU2002210514A1 (en) 2002-04-08
WO2002026996A2 (fr) 2002-04-04

Similar Documents

Publication Publication Date Title
WO2002010403A3 (fr) Regulation d'une enzyme humaine de type phospholipase c a phosphatidylinositol specifique
WO2002026996A3 (fr) Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol
WO2002006453A3 (fr) Regulation de protease a serine humaine de type desc1
WO2002031160A3 (fr) Regulation de l'enzyme de type a2 phospholipase humaine
WO2002000704A3 (fr) Regulation d'une enzyme du type phospholipase c humaine
WO2002031162A3 (fr) Regulation de l'enzyme du type phospholipase a2 humaine
WO2002031125A3 (fr) Regulation de l'enzyme semblable a phospholipase a2 humaine
WO2002042435A3 (fr) Regulation de la tyrosine phosphatase humaine
WO2002020732A3 (fr) Régulation d'enzyme humaine de type map kinase phosphatase
WO2001077149A3 (fr) Regulation d'une proteine gpcr type cyslt2 humaine
WO2002031161A3 (fr) Regulation de l'enzyme humaine de type phospholipase
WO2002092798A3 (fr) Regulation d'une proteine humaine de type 2c de phosphatase acide phosphatidique
WO2002020747A3 (fr) Regulation de l'enzyme humaine du type tyrosine phosphatase
WO2002090543A3 (fr) Régulation de la protéine semblable à celle de type 2c de la phosphatase de l'acide phosphatidique humain
WO2003052088A3 (fr) Regulation de la sialyltransferase humaine
WO2002062974A3 (fr) Regulation de la proteine humaine elongase hselo1
WO2002088362A3 (fr) Regulation d'une proteine semblable a la prostaglandine-f synthase 1 humaine
WO2002033056A3 (fr) Regulation de serine-threonine kinase humaine
WO2002061058A3 (fr) Regulation de la phospholipase humaine
WO2002062975A3 (fr) Regulation de la proteine humaine du type elongase hselo1
WO2002033095A3 (fr) Regulation de serine-threonine proteine kinase humaine
WO2002055710A3 (fr) Regulation de l'acide phosphatase pourpre humain
WO2002057461A3 (fr) Regulation de la metalloprotease a zinc de type adam-ts humaine
WO2003018815A3 (fr) Regulation de la grk humaine
WO2002006455A3 (fr) Regulation de l'enzyme de type trypsine protease humaine des voies respiratoires

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP