WO2002020464A3 - Benzene tricarboxylic acid amides as insulin receptor activators - Google Patents
Benzene tricarboxylic acid amides as insulin receptor activators Download PDFInfo
- Publication number
- WO2002020464A3 WO2002020464A3 PCT/US2001/028084 US0128084W WO0220464A3 WO 2002020464 A3 WO2002020464 A3 WO 2002020464A3 US 0128084 W US0128084 W US 0128084W WO 0220464 A3 WO0220464 A3 WO 0220464A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- acid amides
- insulin receptor
- tricarboxylic acid
- benzene tricarboxylic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/51—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK01968657T DK1315695T3 (en) | 2000-09-07 | 2001-09-06 | Bone centric carboxylic acid amides as activators of insulin receptors |
CA002421581A CA2421581A1 (en) | 2000-09-07 | 2001-09-06 | Benzene tricarboxylic acid amides as insulin receptor activators |
DE60111948T DE60111948T2 (en) | 2000-09-07 | 2001-09-06 | BENZOLIC ACETIC ACID AMIDES AS INSULIN RECEPTOR ACTIVATORS |
AU8889101A AU8889101A (en) | 2000-09-07 | 2001-09-06 | Benzene tricarboxylic acid derivatives as insulin receptor activators |
JP2002525087A JP2004508348A (en) | 2000-09-07 | 2001-09-06 | Benzenetricarboxylic acid-derived counterparts as insulin receptor activators |
EP01968657A EP1315695B1 (en) | 2000-09-07 | 2001-09-06 | Benzene tricarboxylic acid amides as insulin receptor activators |
AT01968657T ATE299491T1 (en) | 2000-09-07 | 2001-09-06 | BENZOLETRICARBONONIC ACID AMIDES AS ACTIVATORS OF THE INSULIN RECEPTOR |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23073800P | 2000-09-07 | 2000-09-07 | |
US60/230,738 | 2000-09-07 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2002020464A2 WO2002020464A2 (en) | 2002-03-14 |
WO2002020464A3 true WO2002020464A3 (en) | 2002-06-20 |
WO2002020464A8 WO2002020464A8 (en) | 2003-07-10 |
Family
ID=22866366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/028084 WO2002020464A2 (en) | 2000-09-07 | 2001-09-06 | Benzene tricarboxylic acid amides as insulin receptor activators |
Country Status (12)
Country | Link |
---|---|
US (1) | US6600069B2 (en) |
EP (1) | EP1315695B1 (en) |
JP (1) | JP2004508348A (en) |
AR (1) | AR030620A1 (en) |
AT (1) | ATE299491T1 (en) |
AU (1) | AU8889101A (en) |
CA (1) | CA2421581A1 (en) |
DE (1) | DE60111948T2 (en) |
DK (1) | DK1315695T3 (en) |
ES (1) | ES2241867T3 (en) |
TW (1) | TWI283660B (en) |
WO (1) | WO2002020464A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1391474B1 (en) * | 2008-10-02 | 2011-12-23 | Università Degli Studi Di Roma La Sapienza | CARBONYL DERIVATIVES AT C3 SYMMETRY, THEIR PREPARATION AND THEIR USE |
KR101121954B1 (en) | 2010-05-13 | 2012-03-09 | 아주대학교산학협력단 | Composition for preventing or treating diabetes comprising 1,2,3-Benzentricarboxylic acid |
JP6255210B2 (en) * | 2013-10-24 | 2017-12-27 | アーゼッド・エレクトロニック・マテリアルズ(ルクセンブルグ)ソシエテ・ア・レスポンサビリテ・リミテ | Resist underlayer film forming composition |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4089974A (en) * | 1977-06-13 | 1978-05-16 | American Cyanamid Company | 5-Carboxy-phenylenebis(carbonylimino)benzene carboxylic and dicarboxylic acids and salts |
US4123455A (en) * | 1977-06-13 | 1978-10-31 | American Cyanamid Company | Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts |
DE3327191A1 (en) * | 1982-08-07 | 1984-02-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Process for compacting anodically oxidised aluminium surfaces |
DE4229182A1 (en) * | 1992-09-02 | 1994-03-03 | Basf Ag | New metal chelate cpds., used in organic ferromagnets - prepd. from aromatic tri:carboxylic acid, aromatic or hetero-aromatic amine and metal salt, giving lightweight magnet |
WO1996014324A1 (en) * | 1994-11-07 | 1996-05-17 | American Home Products Corporation | Smooth muscle cell proliferation inhibitors |
EP0741128A2 (en) * | 1995-05-05 | 1996-11-06 | F. Hoffmann-La Roche Ag | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls |
JPH08333324A (en) * | 1995-06-08 | 1996-12-17 | Terumo Corp | Benzene derivative and pharmaceutical preparation containing the same |
JPH09258359A (en) * | 1996-01-19 | 1997-10-03 | Fuji Photo Film Co Ltd | Silver halide photographic sensitive material and its processing method |
US5750573A (en) * | 1994-01-21 | 1998-05-12 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
US5973076A (en) * | 1995-05-31 | 1999-10-26 | New Japan Chemical Co., Ltd. | Polybutene-1 resin composition and a method of accelerating the crystal transformation thereof |
FR2796942A1 (en) * | 1999-07-29 | 2001-02-02 | Telik Inc | NEW NAPHYLSULPHONIC ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046805A (en) | 1976-05-10 | 1977-09-06 | American Cyanamid Company | Substituted-hydroxy-naphthalenedisulfonic acid compounds |
US4051176A (en) | 1976-05-10 | 1977-09-27 | American Cyanamid Company | Ureidophenylenebis(carbonylimino)dinaphthalenetrisulfonic acid compounds |
US4129591A (en) | 1976-10-27 | 1978-12-12 | American Cyanamid Company | Ureida-phenylenebis(substituted imino)multianionic substituted dinaphthalene sulfonic acids and salts |
US4102917A (en) | 1977-06-01 | 1978-07-25 | American Cyanamid Company | Substituted phenyl naphthalenesulfonic acids |
US4120895A (en) | 1977-06-29 | 1978-10-17 | American Cyanamid Company | S-phenenyltris (iminocarbonyl) triisophthalic acid salts |
US4120891A (en) | 1977-07-01 | 1978-10-17 | American Cyanamid Company | Ureylene naphthalene sulfonic acids |
US4118585A (en) | 1977-07-01 | 1978-10-03 | American Cyanamid Company | Anionic benzene tetrakis carbonylimino isophthalic acid salts |
US4132730A (en) | 1977-07-29 | 1979-01-02 | American Cyanamid Company | Ureylene naphthalene sulfonic acids |
US4229371A (en) * | 1977-07-29 | 1980-10-21 | American Cyanamid Company | Ureylene naphthalene sulfonic acid intermediates |
EP1277790A3 (en) | 1998-03-04 | 2004-07-28 | Ciba SC Holding AG | Nucleators for crystallizable thermoplastic polymers |
-
2001
- 2001-09-06 DK DK01968657T patent/DK1315695T3/en active
- 2001-09-06 DE DE60111948T patent/DE60111948T2/en not_active Expired - Fee Related
- 2001-09-06 WO PCT/US2001/028084 patent/WO2002020464A2/en active IP Right Grant
- 2001-09-06 JP JP2002525087A patent/JP2004508348A/en not_active Withdrawn
- 2001-09-06 US US09/949,165 patent/US6600069B2/en not_active Expired - Fee Related
- 2001-09-06 EP EP01968657A patent/EP1315695B1/en not_active Expired - Lifetime
- 2001-09-06 AR ARP010104240A patent/AR030620A1/en unknown
- 2001-09-06 TW TW090122095A patent/TWI283660B/en not_active IP Right Cessation
- 2001-09-06 CA CA002421581A patent/CA2421581A1/en not_active Abandoned
- 2001-09-06 AT AT01968657T patent/ATE299491T1/en not_active IP Right Cessation
- 2001-09-06 ES ES01968657T patent/ES2241867T3/en not_active Expired - Lifetime
- 2001-09-06 AU AU8889101A patent/AU8889101A/en not_active Withdrawn
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4089974A (en) * | 1977-06-13 | 1978-05-16 | American Cyanamid Company | 5-Carboxy-phenylenebis(carbonylimino)benzene carboxylic and dicarboxylic acids and salts |
US4123455A (en) * | 1977-06-13 | 1978-10-31 | American Cyanamid Company | Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts |
DE3327191A1 (en) * | 1982-08-07 | 1984-02-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Process for compacting anodically oxidised aluminium surfaces |
DE4229182A1 (en) * | 1992-09-02 | 1994-03-03 | Basf Ag | New metal chelate cpds., used in organic ferromagnets - prepd. from aromatic tri:carboxylic acid, aromatic or hetero-aromatic amine and metal salt, giving lightweight magnet |
US5750573A (en) * | 1994-01-21 | 1998-05-12 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
WO1996014324A1 (en) * | 1994-11-07 | 1996-05-17 | American Home Products Corporation | Smooth muscle cell proliferation inhibitors |
EP0741128A2 (en) * | 1995-05-05 | 1996-11-06 | F. Hoffmann-La Roche Ag | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls |
US5973076A (en) * | 1995-05-31 | 1999-10-26 | New Japan Chemical Co., Ltd. | Polybutene-1 resin composition and a method of accelerating the crystal transformation thereof |
JPH08333324A (en) * | 1995-06-08 | 1996-12-17 | Terumo Corp | Benzene derivative and pharmaceutical preparation containing the same |
JPH09258359A (en) * | 1996-01-19 | 1997-10-03 | Fuji Photo Film Co Ltd | Silver halide photographic sensitive material and its processing method |
FR2796942A1 (en) * | 1999-07-29 | 2001-02-02 | Telik Inc | NEW NAPHYLSULPHONIC ACIDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
Non-Patent Citations (3)
Title |
---|
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002193995, retrieved from STN Database accession no. 127:364123/DN, HCAPLUS * |
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002193996, retrieved from STN Database accession no. 126:152810/DN, HCAPLUS * |
HARRIS, WESLEY R. ET AL., J. AM. CHEM. SOC., vol. 103, 1981, pages 2667 - 2675, XP002193994 * |
Also Published As
Publication number | Publication date |
---|---|
JP2004508348A (en) | 2004-03-18 |
AR030620A1 (en) | 2003-08-27 |
AU8889101A (en) | 2002-03-22 |
US20020103183A1 (en) | 2002-08-01 |
ATE299491T1 (en) | 2005-07-15 |
TWI283660B (en) | 2007-07-11 |
EP1315695A2 (en) | 2003-06-04 |
WO2002020464A8 (en) | 2003-07-10 |
DE60111948D1 (en) | 2005-08-18 |
DK1315695T3 (en) | 2005-08-08 |
CA2421581A1 (en) | 2002-03-14 |
EP1315695B1 (en) | 2005-07-13 |
WO2002020464A2 (en) | 2002-03-14 |
US6600069B2 (en) | 2003-07-29 |
ES2241867T3 (en) | 2005-11-01 |
DE60111948T2 (en) | 2006-04-20 |
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