WO2002018566A3 - Regulation of human l-asparaginase-like enzyme - Google Patents

Regulation of human l-asparaginase-like enzyme Download PDF

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Publication number
WO2002018566A3
WO2002018566A3 PCT/EP2001/009607 EP0109607W WO0218566A3 WO 2002018566 A3 WO2002018566 A3 WO 2002018566A3 EP 0109607 W EP0109607 W EP 0109607W WO 0218566 A3 WO0218566 A3 WO 0218566A3
Authority
WO
WIPO (PCT)
Prior art keywords
asparaginase
human
enzyme
regulation
reagents
Prior art date
Application number
PCT/EP2001/009607
Other languages
French (fr)
Other versions
WO2002018566A2 (en
Inventor
Timothy J Smith
Original Assignee
Bayer Ag
Timothy J Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Timothy J Smith filed Critical Bayer Ag
Priority to AU2001282109A priority Critical patent/AU2001282109A1/en
Publication of WO2002018566A2 publication Critical patent/WO2002018566A2/en
Publication of WO2002018566A3 publication Critical patent/WO2002018566A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human L-asparaginase-like enzyme and reagents which bind to human L-asparaginase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and CNS disorders.
PCT/EP2001/009607 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme WO2002018566A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001282109A AU2001282109A1 (en) 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22905500P 2000-08-31 2000-08-31
US60/229,055 2000-08-31

Publications (2)

Publication Number Publication Date
WO2002018566A2 WO2002018566A2 (en) 2002-03-07
WO2002018566A3 true WO2002018566A3 (en) 2003-01-30

Family

ID=22859671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009607 WO2002018566A2 (en) 2000-08-31 2001-08-21 Regulation of human l-asparaginase-like enzyme

Country Status (2)

Country Link
AU (1) AU2001282109A1 (en)
WO (1) WO2002018566A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016334A2 (en) * 1999-09-01 2001-03-08 Incyte Genomics, Inc. Human hydrolytic enzymes
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016334A2 (en) * 1999-09-01 2001-03-08 Incyte Genomics, Inc. Human hydrolytic enzymes
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI [online] 1 October 2000 (2000-10-01), XP002213531, Database accession no. Q9NXJ2 *
DATABASE EBI [online] 22 February 2000 (2000-02-22), WATANABE ET AL: "NEDO human cDNA sequencing project", XP002213530, Database accession no. AK000219 *
DATABASE EBI [online] 22 October 2001 (2001-10-22), XP002213532, Database accession no. AAM40221 *
DATABASE EBI [online] 22 October 2001 (2001-10-22), XP002213533, Database accession no. AAI61163 *

Also Published As

Publication number Publication date
AU2001282109A1 (en) 2002-03-13
WO2002018566A2 (en) 2002-03-07

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