WO2002004514A3 - Compositions et procedes pour le traitement et le diagnostic du cancer du poumon - Google Patents

Compositions et procedes pour le traitement et le diagnostic du cancer du poumon Download PDF

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Publication number
WO2002004514A3
WO2002004514A3 PCT/US2001/022058 US0122058W WO0204514A3 WO 2002004514 A3 WO2002004514 A3 WO 2002004514A3 US 0122058 W US0122058 W US 0122058W WO 0204514 A3 WO0204514 A3 WO 0204514A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
diagnosis
lung cancer
therapy
polypeptides
Prior art date
Application number
PCT/US2001/022058
Other languages
English (en)
Other versions
WO2002004514A2 (fr
WO2002004514A8 (fr
Inventor
Tongtong Wang
Yoshihiro Watanabe
Robert A Henderson
Jeffrey C Johnson
Marc W Retter
Margarita Durham
Darrick Carter
Gary Richard Fanger
Thomas S Vedvick
Chaitanya S Bangur
Andria Mcnabb
Aijun Wang
Neil Fanger
Ann Switzer
Patricia D Mcneill
Jonathan D Clapper
Original Assignee
Corixa Corp
Tongtong Wang
Yoshihiro Watanabe
Robert A Henderson
Jeffrey C Johnson
Marc W Retter
Margarita Durham
Darrick Carter
Gary Richard Fanger
Thomas S Vedvick
Chaitanya S Bangur
Andria Mcnabb
Aijun Wang
Neil Fanger
Ann Switzer
Patricia D Mcneill
Jonathan D Clapper
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/614,124 external-priority patent/US6630574B1/en
Priority claimed from US09/651,563 external-priority patent/US6914132B1/en
Priority claimed from US09/658,824 external-priority patent/US6746846B1/en
Priority claimed from US09/671,325 external-priority patent/US6667154B1/en
Priority claimed from US09/702,705 external-priority patent/US6504010B1/en
Priority claimed from US09/736,457 external-priority patent/US6509448B2/en
Priority claimed from US09/849,626 external-priority patent/US20020197669A1/en
Priority to AU2002218770A priority Critical patent/AU2002218770A1/en
Priority to CA002415544A priority patent/CA2415544A1/fr
Application filed by Corixa Corp, Tongtong Wang, Yoshihiro Watanabe, Robert A Henderson, Jeffrey C Johnson, Marc W Retter, Margarita Durham, Darrick Carter, Gary Richard Fanger, Thomas S Vedvick, Chaitanya S Bangur, Andria Mcnabb, Aijun Wang, Neil Fanger, Ann Switzer, Patricia D Mcneill, Jonathan D Clapper filed Critical Corixa Corp
Priority to EP01984164A priority patent/EP1343886A2/fr
Priority to JP2002509377A priority patent/JP2004512824A/ja
Publication of WO2002004514A2 publication Critical patent/WO2002004514A2/fr
Publication of WO2002004514A8 publication Critical patent/WO2002004514A8/fr
Publication of WO2002004514A3 publication Critical patent/WO2002004514A3/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/462Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622Antigen presenting cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne des compositions et des procédés pour le traitement et le diagnostic du cancer, en particulier du cancer du poumon. Les compositions typiques comprennent un ou plusieurs polypeptides de tumeur pulmonaire, des parties immunogènes de ceux-ci, des polynucléotides qui codent pour ces polypeptides, une cellules présentatrice d'antigène qui exprime ces polypeptides, et des lymphocytes T spécifiques de cellules exprimant ces polypeptides. Les compositions décrites sont utiles, par exemple, dans le diagnostic, la prévention et/ou le traitement de maladies, en particulier le cancer du poumon.
PCT/US2001/022058 2000-07-11 2001-07-10 Compositions et procedes pour le traitement et le diagnostic du cancer du poumon WO2002004514A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002509377A JP2004512824A (ja) 2000-07-11 2001-07-10 肺癌の治療および診断のための組成物および方法
EP01984164A EP1343886A2 (fr) 2000-07-11 2001-07-10 Compositions et procedes pour le traitement et le diagnostic du cancer du poumon
AU2002218770A AU2002218770A1 (en) 2000-07-11 2001-07-10 Compositions and methods for the therapy and diagnosis of lung cancer
CA002415544A CA2415544A1 (fr) 2000-07-11 2001-07-10 Compositions et procedes pour le traitement et le diagnostic du cancer du poumon

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US09/614,124 2000-07-11
US09/614,124 US6630574B1 (en) 1999-06-30 2000-07-11 Compositions and methods for the therapy and diagnosis of lung cancer
US09/651,563 US6914132B1 (en) 1999-06-30 2000-08-29 Compositions and methods for the therapy and diagnosis of lung cancer
US09/651,563 2000-08-29
US09/658,824 US6746846B1 (en) 1999-06-30 2000-09-08 Methods for diagnosing lung cancer
US09/658,824 2000-09-08
US09/671,325 US6667154B1 (en) 1999-06-30 2000-09-26 Compositions and methods for the therapy and diagnosis of lung cancer
US09/671,325 2000-09-26
US67741900A 2000-10-06 2000-10-06
US09/677,419 2000-10-06
US09/702,705 2000-10-30
US09/702,705 US6504010B1 (en) 1999-06-30 2000-10-30 Compositions and methods for the therapy and diagnosis of lung cancer
US09/736,457 2000-12-13
US09/736,457 US6509448B2 (en) 1999-06-30 2000-12-13 Compositions and methods for the therapy and diagnosis of lung cancer
US09/849,626 2001-05-03
US09/849,626 US20020197669A1 (en) 2000-12-13 2001-05-03 Compositions and methods for the therapy and diagnosis of lung cancer

Publications (3)

Publication Number Publication Date
WO2002004514A2 WO2002004514A2 (fr) 2002-01-17
WO2002004514A8 WO2002004514A8 (fr) 2002-12-27
WO2002004514A3 true WO2002004514A3 (fr) 2003-06-19

Family

ID=27575493

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022058 WO2002004514A2 (fr) 2000-07-11 2001-07-10 Compositions et procedes pour le traitement et le diagnostic du cancer du poumon

Country Status (6)

Country Link
EP (1) EP1343886A2 (fr)
JP (1) JP2004512824A (fr)
AR (1) AR031250A1 (fr)
AU (1) AU2002218770A1 (fr)
CA (1) CA2415544A1 (fr)
WO (1) WO2002004514A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170255A1 (en) * 1999-06-30 2003-09-11 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20030211510A1 (en) 1999-06-30 2003-11-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6893818B1 (en) 1999-10-28 2005-05-17 Agensys, Inc. Gene upregulated in cancers of the prostate
EP1661996A1 (fr) * 1999-12-01 2006-05-31 Genentech, Inc. Polypeptides sécrétés et transmembranaires ainsi que les acides nucléiques codant pour ceux-ci
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
ZA200204907B (en) 2001-06-26 2003-03-03 Univ Nat Taiwan Collapsin Response Mediator Protein-1.
AU2003256106A1 (en) * 2002-08-14 2004-03-03 Lg Life Sciences Ltd. Gene families associated with liver cancer
CA2499623A1 (fr) * 2002-09-26 2004-04-08 Genentech, Inc. Nouvelles compositions et methodes destinees au traitement du psoriasis
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7449291B1 (en) * 2003-01-13 2008-11-11 University Of Washington Methods for identifying subjects susceptible to Charcot-Marie-Tooth neuropathy type 1C
WO2004070058A1 (fr) * 2003-02-03 2004-08-19 Bayer Healthcare Ag Methodes et compositions permettant de prevoir, diagnostiquer, pronostiquer, prevenir et traiter des broncho-pneumopathies chroniques obstructives
JP2006521110A (ja) * 2003-03-24 2006-09-21 コリクサ コーポレイション 肺癌の検出およびモニタリング
JP4643450B2 (ja) 2003-08-08 2011-03-02 株式会社ペルセウスプロテオミクス 癌高発現遺伝子
EP1668354A2 (fr) 2003-09-24 2006-06-14 Oncotherapy Science, Inc. Methode de diagnostic du cancer du sein
JP4428995B2 (ja) 2003-12-03 2010-03-10 関東化学株式会社 金属膜のエッチング液組成物
CA2555509A1 (fr) * 2004-01-27 2005-07-27 Compugen Usa, Inc. Nouvelles sequences d'acides amines et de nucleotides, et dosages et methodes d'utilisation connexes pour le diagnostic du cancer du poumon
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
US8940488B2 (en) 2004-03-31 2015-01-27 Hiroyuki Aburatani Cancer diagnosis and treatment of cancer using anti-robo 1 antibody
CA2565175C (fr) 2004-03-31 2017-12-19 Chugai Seiyaku Kabushiki Kaisha Diagnostic du cancer et traitement utilisant l'anticorps anti-robo1
EP1915622A2 (fr) * 2005-07-29 2008-04-30 Oncotherapy Science, Inc. Criblage et methode therapeutique anti-nsclc ciblant le complexe cda1-kntc2
US20110038849A1 (en) * 2006-12-21 2011-02-17 Intradigm Corporation Inhibitory polynucleotide compositions and methods for treating cancer
JP5117765B2 (ja) 2007-05-28 2013-01-16 国立大学法人 東京大学 抗robo1抗体を含むpet用腫瘍診断剤
CA2696701C (fr) 2007-08-20 2017-01-24 Oncotherapy Science, Inc. Peptide cdca1 et agent pharmaceutique le comprenant
TWI526219B (zh) 2008-06-19 2016-03-21 腫瘤療法 科學股份有限公司 Cdca1抗原決定位胜肽及含此胜肽的疫苗
JP5709108B2 (ja) * 2009-05-22 2015-04-30 国立大学法人 岡山大学 XAGE−1b特異的免疫反応を誘導するペプチドおよびその利用
US9687538B2 (en) * 2012-07-10 2017-06-27 Oncotherapy Science, Inc. CDCA1 epitope peptides for Th1 cells and vaccines containing the same
CN114102955B (zh) * 2020-08-31 2024-05-07 天津科技大学 一种采用常温发泡技术制备发泡聚乳酸的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038973A2 (fr) * 1998-01-28 1999-08-05 Corixa Corporation Composes destines au diagnostic et a la therapie du cancer du poumon et procedes d'utilisation associes
WO2000055375A1 (fr) * 1999-03-17 2000-09-21 Alphagene, Inc. Proteines secretees et polynucleotides les codant

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JPH10139800A (ja) * 1996-11-15 1998-05-26 Santen Pharmaceut Co Ltd シェーグレン症候群治療剤
CN1367829A (zh) * 1999-06-30 2002-09-04 科里克萨有限公司 用于肺癌治疗和诊断的组合物和方法

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WO2000055375A1 (fr) * 1999-03-17 2000-09-21 Alphagene, Inc. Proteines secretees et polynucleotides les codant

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Also Published As

Publication number Publication date
WO2002004514A2 (fr) 2002-01-17
WO2002004514A8 (fr) 2002-12-27
AR031250A1 (es) 2003-09-17
JP2004512824A (ja) 2004-04-30
CA2415544A1 (fr) 2002-01-17
AU2002218770A1 (en) 2002-01-21
EP1343886A2 (fr) 2003-09-17

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