WO2001007041A1 - Antiarrhythmic drug - Google Patents
Antiarrhythmic drug Download PDFInfo
- Publication number
- WO2001007041A1 WO2001007041A1 PCT/BG2000/000020 BG0000020W WO0107041A1 WO 2001007041 A1 WO2001007041 A1 WO 2001007041A1 BG 0000020 W BG0000020 W BG 0000020W WO 0107041 A1 WO0107041 A1 WO 0107041A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- hydrochloride
- amiodarone
- well
- amiοdaροn
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Definitions
- ammonium hydroxide they are mixed with 40 weight percent micro-crystalline cellulose (Witzel ⁇ 102) and 64 weight percent water.
- the Rhythmic Medicinal Product is used using the following process mode:
- a large quantity of amidodrum hydrated and sweetened with sodium gluten is at a loss of 2.3: 1 and is switched off. and the composition is moisturized with a compound of ⁇ 64 and 96% ethanol.
- Moisturized mass is allowed to be granulated and dried at a temperature of 40 - 50 ° ⁇ to obtain residual moisture in the amount of 3% and is not allowed to be consumed.
- a dry granule a ⁇ 200 manifold is added, a basic oxide brown, talc and magnesium stearate. After homogenization from the mixture, the tablets are manufactured on a portable laptop with flat plugs with a diameter of 10 mm with an integrated and separate line.
- the invention may be clarified on the basis of the following examples: REMARK 1.
- ⁇ ezul ⁇ a ⁇ y is ⁇ y ⁇ any ⁇ ⁇ g ⁇ on s ⁇ e ⁇ en ⁇ as ⁇ v ⁇ eniya ami ⁇ da ⁇ n gid ⁇ l ⁇ ida of s ⁇ s ⁇ ava ⁇ lezn ⁇ y m ⁇ deli ⁇ edl ⁇ zhenn ⁇ g ⁇ le ⁇ a ⁇ s ⁇ venn ⁇ g ⁇ s ⁇ eds ⁇ va ⁇ i ⁇ able ⁇ a ⁇ ami ⁇ da ⁇ na ⁇ 200 mg s ⁇ avni ⁇ elny ⁇ ⁇ b ⁇ azts ⁇ v, ⁇ a ⁇ zhe s ⁇ de ⁇ zhaschi ⁇ 200 mg ami ⁇ da ⁇ n gid ⁇ l ⁇ ida ⁇ eds ⁇ avleny in ⁇ ablitse
- the area at the front ( ⁇ ) at the plasma concentration is available (from 0 to 24 ⁇ ) at the place of the owner, (it is completely)
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EA200100275A EA003052B1 (en) | 1999-07-27 | 2000-07-21 | Antiarrythmic drug |
AU62558/00A AU6255800A (en) | 1999-07-27 | 2000-07-27 | Antiarrhythmic drug |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BG103607 | 1999-07-27 | ||
BG10360799 | 1999-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001007041A1 true WO2001007041A1 (en) | 2001-02-01 |
Family
ID=3927839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/BG2000/000020 WO2001007041A1 (en) | 1999-07-27 | 2000-07-27 | Antiarrhythmic drug |
Country Status (4)
Country | Link |
---|---|
AU (1) | AU6255800A (en) |
EA (1) | EA003052B1 (en) |
LT (1) | LT4899B (en) |
WO (1) | WO2001007041A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10894049B2 (en) | 2016-03-29 | 2021-01-19 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical formulation of palbociclib and a preparation method thereof |
US11471418B2 (en) | 2020-09-29 | 2022-10-18 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical compositions of amorphous solid dispersions and methods of preparation thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997034597A1 (en) * | 1996-03-18 | 1997-09-25 | Sanofi | Use of antiarrhythmic compounds for reducing post-infarction mortality |
WO1998046214A1 (en) * | 1997-04-11 | 1998-10-22 | Upsher-Smith Laboratories, Inc. | Pharmaceutical tablet of amiodarone salt |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0330284B1 (en) | 1988-02-25 | 1994-07-27 | Yamanouchi Europe B.V. | Process for the preparation of a pharmaceutical granulate |
-
2000
- 2000-07-21 EA EA200100275A patent/EA003052B1/en not_active IP Right Cessation
- 2000-07-27 AU AU62558/00A patent/AU6255800A/en not_active Abandoned
- 2000-07-27 WO PCT/BG2000/000020 patent/WO2001007041A1/en not_active Application Discontinuation
-
2001
- 2001-03-28 LT LT2001034A patent/LT4899B/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997034597A1 (en) * | 1996-03-18 | 1997-09-25 | Sanofi | Use of antiarrhythmic compounds for reducing post-infarction mortality |
WO1998046214A1 (en) * | 1997-04-11 | 1998-10-22 | Upsher-Smith Laboratories, Inc. | Pharmaceutical tablet of amiodarone salt |
Non-Patent Citations (1)
Title |
---|
MASHKOVSKY M.D., "Lekarstvennye sredstva", Moscow, Meditsina, 1986, pages 425- 426. * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10894049B2 (en) | 2016-03-29 | 2021-01-19 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical formulation of palbociclib and a preparation method thereof |
US11471418B2 (en) | 2020-09-29 | 2022-10-18 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical compositions of amorphous solid dispersions and methods of preparation thereof |
Also Published As
Publication number | Publication date |
---|---|
EA003052B1 (en) | 2002-12-26 |
EA200100275A1 (en) | 2001-08-27 |
LT2001034A (en) | 2001-10-25 |
LT4899B (en) | 2002-03-25 |
AU6255800A (en) | 2001-02-13 |
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