WO2000064977A8 - In situ forming hydrogels - Google Patents

In situ forming hydrogels

Info

Publication number
WO2000064977A8
WO2000064977A8 PCT/US2000/011691 US0011691W WO0064977A8 WO 2000064977 A8 WO2000064977 A8 WO 2000064977A8 US 0011691 W US0011691 W US 0011691W WO 0064977 A8 WO0064977 A8 WO 0064977A8
Authority
WO
WIPO (PCT)
Prior art keywords
situ forming
forming hydrogels
methods
situ
hydrogel
Prior art date
Application number
PCT/US2000/011691
Other languages
French (fr)
Other versions
WO2000064977A1 (en
Inventor
Jeffrey A Hubbell
Julia A Kornfield
Giyoong Tae
Original Assignee
California Inst Of Techn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn filed Critical California Inst Of Techn
Priority to AU49778/00A priority Critical patent/AU4977800A/en
Priority to EP00931980A priority patent/EP1173517A4/en
Publication of WO2000064977A1 publication Critical patent/WO2000064977A1/en
Publication of WO2000064977A8 publication Critical patent/WO2000064977A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof

Abstract

The invention features materials and methods for the liquid to solid transition of an injectable pre-hydrogel composition to a hydrogel. These methods can be carried out in situ.
PCT/US2000/011691 1999-04-26 2000-04-26 In situ forming hydrogels WO2000064977A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU49778/00A AU4977800A (en) 1999-04-26 2000-04-26 (in situ) forming hydrogels
EP00931980A EP1173517A4 (en) 1999-04-26 2000-04-26 In situ forming hydrogels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13116499P 1999-04-26 1999-04-26
US60/133,164 1999-04-26

Publications (2)

Publication Number Publication Date
WO2000064977A1 WO2000064977A1 (en) 2000-11-02
WO2000064977A8 true WO2000064977A8 (en) 2001-05-03

Family

ID=36423498

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/011691 WO2000064977A1 (en) 1999-04-26 2000-04-26 In situ forming hydrogels

Country Status (3)

Country Link
EP (1) EP1173517A4 (en)
AU (1) AU4977800A (en)
WO (1) WO2000064977A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486558B2 (en) 2003-03-27 2016-11-08 Locate Therapeutics Limited Porous matrix

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2361563A1 (en) * 1999-12-08 2001-06-14 Ljubov Leonidovna Mironova Use of polyacrylamide gel for forming a connective-tissue capsule in a mammal for cultivating allogenic or xenogenic cells
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
AU4566001A (en) 2000-03-13 2001-09-24 Biocure Inc Embolic compositions
SG98393A1 (en) 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
US20020122771A1 (en) * 2000-09-23 2002-09-05 Troy Holland Spray hydrogel wound dressings
ES2601143T3 (en) 2002-07-19 2017-02-14 Omeros Corporation Biodegradable triblock copolymers, synthesis methods thereof, and hydrogels and biomaterials prepared therefrom.
CA2520012A1 (en) 2003-03-25 2004-10-14 Biocure, Inc. Hydrogel string medical device
JP2008510021A (en) 2004-06-29 2008-04-03 バイオキュア・インコーポレーテッド Biomaterial
US20080069857A1 (en) * 2006-04-12 2008-03-20 Yoon Yeo Compositions And Methods For Inhibiting Adhesions
WO2009148985A2 (en) 2008-06-03 2009-12-10 E. I. Du Pont De Nemours And Company A tissue coating for preventing undesired tissue-to-tissue adhesions
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
CN107428930B (en) 2015-03-10 2020-01-17 国立大学法人东京大学 Method for producing low-concentration gel using gel precursor cluster, and gel obtained by the production method
WO2017083779A1 (en) 2015-11-12 2017-05-18 Graybug Vision, Inc. Aggregating microparticles for therapy
CA3056923A1 (en) 2017-03-23 2018-09-27 Graybug Vision, Inc. Drugs and compositions for the treatment of ocular disorders
JP2020519585A (en) 2017-05-10 2020-07-02 グレイバグ ビジョン インコーポレイテッド Extended release microparticles and suspensions thereof for medical therapy
CN112898584B (en) * 2021-01-21 2022-03-08 中国科学院苏州纳米技术与纳米仿生研究所 Solid-solid supermolecule phase change material and preparation method and application thereof
CN113143851A (en) * 2021-03-02 2021-07-23 复旦大学 Solvent exchange-based injectable hydrogel and preparation method and application thereof
CN114425101B (en) * 2022-01-21 2022-07-22 北京大学口腔医学院 Micro-nano double-layer structure antibacterial bracket and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
WO1995035093A1 (en) * 1994-06-17 1995-12-28 University Of Nebraska Board Of Regents In situ gel-forming delivery vehicle for bio-affecting substances, and method of use
US5976648A (en) * 1995-12-14 1999-11-02 Kimberly-Clark Worldwide, Inc. Synthesis and use of heterogeneous polymer gels

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486558B2 (en) 2003-03-27 2016-11-08 Locate Therapeutics Limited Porous matrix

Also Published As

Publication number Publication date
AU4977800A (en) 2000-11-10
EP1173517A1 (en) 2002-01-23
EP1173517A4 (en) 2006-06-28
WO2000064977A1 (en) 2000-11-02

Similar Documents

Publication Publication Date Title
WO2000064977A8 (en) In situ forming hydrogels
AU2002359410A1 (en) Methods for initiating in situ formation of hydrogels
AU5735999A (en) Method for reducing the quantity of residual monomers in aqueous polymeric dispersions
AU3887701A (en) Asphalt and heavy oil degreaser
WO2002047608A3 (en) Cosmetic composition comprising hetero polymers and a solid substance and method of using same
AU2001259312A1 (en) Process for improving the adhesion of polymeric materials to metal surfaces
AU3887801A (en) Asphalt and heavy oil degreaser
AU1198601A (en) Composition and method for stable injectable liquids
AU3493900A (en) One-part moisture-curable hydrocarbon polymer composition
AU2003904009A0 (en) Relocatable reclaiming plant and process
AUPQ018999A0 (en) Compositions and methods for curing concrete
AU2002211080A1 (en) Method and apparatus for the recycling of bituminous materials, more in particular bituminous roofcovering materials
AU2905001A (en) Materials for enhancing electrolytic cavitation reactions and methods for makingthe same
AU5057600A (en) Component and method for the production thereof
AU7647400A (en) Surface finished concrete blocks, method for the production and use thereof
AU2001281349A1 (en) Bituminous substance removal composition
AU2912600A (en) Substituted bicyclic heterocycles and the use thereof as thrombin inhibitors
AU1156301A (en) Composition and process for oil extraction
AU2001253300A1 (en) Heavy oil-solid composition and method for preparing the same
AU2645399A (en) Electrochemical capacitor and method for making the same
AU4809000A (en) Method and composition for waterproofing
AU1198201A (en) Container with non-uniform internal surface
AU7264700A (en) Two-chamber container and method for gassing the same
AU4883397A (en) Method and composition for roughening the road surface
AU2001228498A1 (en) Device and method for carrying out the electrolysis of bulk material comprising anodically soluble constituents

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)

Free format text: (EXCEPT CN)

AK Designated states

Kind code of ref document: C1

Designated state(s): AU CA CN JP

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: PAT. BUL. 44/2000 UNDER (81) ADD "CN"; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

WWE Wipo information: entry into national phase

Ref document number: 2000931980

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000931980

Country of ref document: EP

NENP Non-entry into the national phase in:

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: 2000931980

Country of ref document: EP

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)