WO2000054747A3 - Method for treating dry eye - Google Patents

Method for treating dry eye Download PDF

Info

Publication number
WO2000054747A3
WO2000054747A3 PCT/US2000/006794 US0006794W WO0054747A3 WO 2000054747 A3 WO2000054747 A3 WO 2000054747A3 US 0006794 W US0006794 W US 0006794W WO 0054747 A3 WO0054747 A3 WO 0054747A3
Authority
WO
WIPO (PCT)
Prior art keywords
eye
dry eye
treating dry
compositions
dry
Prior art date
Application number
PCT/US2000/006794
Other languages
French (fr)
Other versions
WO2000054747A2 (en
Inventor
John Denick Jr
David J Heiler
Zhenze Hu
Joseph C Salamone
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Priority to AU37478/00A priority Critical patent/AU3747800A/en
Publication of WO2000054747A2 publication Critical patent/WO2000054747A2/en
Publication of WO2000054747A3 publication Critical patent/WO2000054747A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is directed to a method of treating dry eye by instilling eyedrops of a composition containing a cationic cellulosic polymer. Such compositions have been found to alleviate the symptoms of dry eye without requiring the presence of anionic therapeutic agents. It is believed that such compositions adhere to dry spots in the eye and, thereby, supplement or promote the presence of mucin, a known lubricant naturally produced by the mucosal tissue of the eye.
PCT/US2000/006794 1999-03-18 2000-03-15 Method for treating dry eye WO2000054747A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU37478/00A AU3747800A (en) 1999-03-18 2000-03-15 Method for treating dry eye

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12495399P 1999-03-18 1999-03-18
US60/124,953 1999-03-18

Publications (2)

Publication Number Publication Date
WO2000054747A2 WO2000054747A2 (en) 2000-09-21
WO2000054747A3 true WO2000054747A3 (en) 2000-12-21

Family

ID=22417580

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/006794 WO2000054747A2 (en) 1999-03-18 2000-03-15 Method for treating dry eye

Country Status (3)

Country Link
AR (1) AR022960A1 (en)
AU (1) AU3747800A (en)
WO (1) WO2000054747A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348508B1 (en) * 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye
MXPA02010749A (en) * 2000-05-02 2003-09-25 Bausch & Lomb Low ionic strength ophthalmic compositions.
EP1421974B1 (en) * 2002-06-10 2006-12-06 D.M.G. Italia Srl Carboxy methyl beta-1, 3 glucan containing ophthalmic solution

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440352A1 (en) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye packing
WO1995000616A1 (en) * 1993-06-18 1995-01-05 Polymer Technology Corporation Composition for wetting contact lenses
WO2000037048A1 (en) * 1998-12-22 2000-06-29 Bausch & Lomb Incorporated Method for treating extended-wear contact lenses in the eyes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440352A1 (en) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye packing
WO1995000616A1 (en) * 1993-06-18 1995-01-05 Polymer Technology Corporation Composition for wetting contact lenses
WO2000037048A1 (en) * 1998-12-22 2000-06-29 Bausch & Lomb Incorporated Method for treating extended-wear contact lenses in the eyes

Also Published As

Publication number Publication date
AU3747800A (en) 2000-10-04
AR022960A1 (en) 2002-09-04
WO2000054747A2 (en) 2000-09-21

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