WO2000002593A3 - Cleansing and treating lotion for treating comedones - Google Patents

Cleansing and treating lotion for treating comedones Download PDF

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Publication number
WO2000002593A3
WO2000002593A3 PCT/FR1999/001684 FR9901684W WO0002593A3 WO 2000002593 A3 WO2000002593 A3 WO 2000002593A3 FR 9901684 W FR9901684 W FR 9901684W WO 0002593 A3 WO0002593 A3 WO 0002593A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
proportions ranging
lotion
treating
acid
Prior art date
Application number
PCT/FR1999/001684
Other languages
French (fr)
Other versions
WO2000002593A2 (en
Inventor
Jacques Peyrot
Jean-Marie Lefevre
Jean-Claude Allart
Original Assignee
Benac Sa
Jacques Peyrot
Lefevre Jean Marie
Allart Jean Claude
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benac Sa, Jacques Peyrot, Lefevre Jean Marie, Allart Jean Claude filed Critical Benac Sa
Priority to EP99929463A priority Critical patent/EP1093360A2/en
Publication of WO2000002593A2 publication Critical patent/WO2000002593A2/en
Publication of WO2000002593A3 publication Critical patent/WO2000002593A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns a composition whereof the synergy of the constituents are designed for curative or preventive treatment of comedones. The composition which is preferably in the form of a lotion, mainly comprises nicotinamide, mandelic acid and C12-C13 alkyl-lactate (or lactate radical). The synergy of these three main constituents is further enhanced by the presence of two other α-hydroxy acids and salicylic acid, and by the gel consistence of the whole composition. More particularly and preferably, said composition comprises: A) three α-hydroxylated acids (AHA), and preferably: mandelic acid in proportions ranging between 2 and 6 %; citric acid in proportions ranging between 0.3 and 3 %; malic acid in proportions ranging between 0.2 and 2 %; B) nicotinamide, or nicotinic amide, (vitamin PP) in proportions ranging between 0.2 and 6 %; C) C12-C13 alkyl-lactate (between 10 and 14 %) in cyclomethicone (in proportions ranging between 18 and 22 %); D) salicylic acid (between 0.5 and 2 %). The composition can be in the form of alcohol fluid gel (lotion) or in the form of 'creams', examples of such presentations are given by way of illustration.
PCT/FR1999/001684 1998-07-09 1999-07-09 Cleansing and treating lotion for treating comedones WO2000002593A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP99929463A EP1093360A2 (en) 1998-07-09 1999-07-09 Cleansing and treating lotion for treating comedones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR98/09576 1998-07-09
FR9809576A FR2780888B1 (en) 1998-07-09 1998-07-09 CLEANSING AND TREATMENT LOTION FOR COMEDON TREATMENT

Publications (2)

Publication Number Publication Date
WO2000002593A2 WO2000002593A2 (en) 2000-01-20
WO2000002593A3 true WO2000002593A3 (en) 2000-08-24

Family

ID=9529051

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1999/001684 WO2000002593A2 (en) 1998-07-09 1999-07-09 Cleansing and treating lotion for treating comedones

Country Status (3)

Country Link
EP (1) EP1093360A2 (en)
FR (1) FR2780888B1 (en)
WO (1) WO2000002593A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29724348U1 (en) 1991-05-15 2001-01-11 Kao Corp., Tokio/Tokyo Keratous comedone remover
US8492366B2 (en) 2002-10-07 2013-07-23 Societe L'oreal S.A. Enhancedly-solubilized beta-hydroxy acids and higher potency skin peels formulated therefrom
US20060008538A1 (en) * 2004-07-07 2006-01-12 Wu Jeffrey M Methods of treating the skin
FR2894142B1 (en) * 2005-12-05 2009-06-12 Oreal USE OF THE TYROSINE-ARGININE DIPEPTIDE AND NIACIMANIDE ASSOCIATION AS A P-SUBSTANCE ANAGONIST
US8858968B2 (en) 2005-12-05 2014-10-14 L'oreal Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
JP6277124B2 (en) * 2011-07-05 2018-02-07 ノヴァン,インコーポレイテッド Topical composition
US8828979B2 (en) * 2012-03-27 2014-09-09 Essential Ingredients, Inc. Salicylic acid gel
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
GB2511350B (en) * 2013-03-01 2016-11-09 Reckitt Benckiser (Brands) Ltd Skincare compositions
BR112015021565B1 (en) * 2013-03-08 2022-10-18 Vantage Specialty Ingredients, Inc COMPOSITION IN THE FORM OF A STABLE GEL, METHOD FOR PREPARING A DILUTED COMPOSITION CONTAINING SALICYLIC ACID, COMPOSITION COMPRISING A STABLE SOLUTION AND PRODUCT
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
WO2016007834A1 (en) 2014-07-11 2016-01-14 Novan, Inc. Topical antiviral compositions and methods of using the same
EP3442502A4 (en) 2016-04-13 2019-11-06 Novan, Inc. Compositions, systems, kits, and methods for treating an infection
CN108210345A (en) * 2018-02-07 2018-06-29 西安加莱利华化妆品有限公司 A kind of vitamin E creams

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105782A (en) * 1975-03-07 1978-08-08 Yu Ruey J Treatment of acne and dandruff
EP0052705A1 (en) * 1980-11-24 1982-06-02 Joel E. Bernstein, M.D. Composition for treating acne vulgaris
US4607101A (en) * 1981-08-27 1986-08-19 Jaye-Boern Laboratories, Inc. Method of treating acne vulgaris with a composition containing carbamide peroxide
WO1995016454A1 (en) * 1993-12-17 1995-06-22 Kligman Albert M Method for treatment of papulo-pustules and comedones of the skin
US5519039A (en) * 1990-03-27 1996-05-21 Leung; Lit-Hung Composition and methods for treatment of acne vulgaris and for retardation of aging
WO1997015282A1 (en) * 1995-10-27 1997-05-01 Medicis Pharmaceutical Corporation Compositions for the treatment of dermatological disorders and methods for their use
EP0775486A1 (en) * 1995-11-23 1997-05-28 Beiersdorf Aktiengesellschaft Antibacterial, antimycotic and antviral compositions based on alpha-hydroxyalkanoic acids and squalene
WO1997018804A1 (en) * 1995-11-21 1997-05-29 Vivante Pharmaceuticals, Inc. Rejuvenating the skin using a combination of vitamin a and alphahydroxy acids
WO1998052927A1 (en) * 1997-05-19 1998-11-26 Rosemarie Scivoletto Composition for treating skin conditions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105782A (en) * 1975-03-07 1978-08-08 Yu Ruey J Treatment of acne and dandruff
EP0052705A1 (en) * 1980-11-24 1982-06-02 Joel E. Bernstein, M.D. Composition for treating acne vulgaris
US4607101A (en) * 1981-08-27 1986-08-19 Jaye-Boern Laboratories, Inc. Method of treating acne vulgaris with a composition containing carbamide peroxide
US5519039A (en) * 1990-03-27 1996-05-21 Leung; Lit-Hung Composition and methods for treatment of acne vulgaris and for retardation of aging
WO1995016454A1 (en) * 1993-12-17 1995-06-22 Kligman Albert M Method for treatment of papulo-pustules and comedones of the skin
WO1997015282A1 (en) * 1995-10-27 1997-05-01 Medicis Pharmaceutical Corporation Compositions for the treatment of dermatological disorders and methods for their use
WO1997018804A1 (en) * 1995-11-21 1997-05-29 Vivante Pharmaceuticals, Inc. Rejuvenating the skin using a combination of vitamin a and alphahydroxy acids
EP0775486A1 (en) * 1995-11-23 1997-05-28 Beiersdorf Aktiengesellschaft Antibacterial, antimycotic and antviral compositions based on alpha-hydroxyalkanoic acids and squalene
WO1998052927A1 (en) * 1997-05-19 1998-11-26 Rosemarie Scivoletto Composition for treating skin conditions

Also Published As

Publication number Publication date
WO2000002593A2 (en) 2000-01-20
FR2780888B1 (en) 2000-10-13
FR2780888A1 (en) 2000-01-14
EP1093360A2 (en) 2001-04-25

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