WO1999054448A3 - Human nucleic acid sequences, increased expression thereof in uterus myoma tissue - Google Patents

Human nucleic acid sequences, increased expression thereof in uterus myoma tissue Download PDF

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Publication number
WO1999054448A3
WO1999054448A3 PCT/DE1999/001178 DE9901178W WO9954448A3 WO 1999054448 A3 WO1999054448 A3 WO 1999054448A3 DE 9901178 W DE9901178 W DE 9901178W WO 9954448 A3 WO9954448 A3 WO 9954448A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid sequences
human nucleic
increased expression
uterus myoma
Prior art date
Application number
PCT/DE1999/001178
Other languages
German (de)
French (fr)
Other versions
WO1999054448A2 (en
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Original Assignee
Metagen Gesellschaft Fuer Genomforschung Mbh
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagen Gesellschaft Fuer Genomforschung Mbh, Thomas Specht, Bernd Hinzmann, Armin Schmitt, Christian Pilarsky, Edgar Dahl, Andre Rosenthal filed Critical Metagen Gesellschaft Fuer Genomforschung Mbh
Priority to JP2000544780A priority Critical patent/JP2002512024A/en
Priority to EP99927686A priority patent/EP1080188A2/en
Publication of WO1999054448A2 publication Critical patent/WO1999054448A2/en
Publication of WO1999054448A3 publication Critical patent/WO1999054448A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention relates to human nucleic acid sequences (mRNA, cDNA, genomic sequences) of uterus myoma tissue, coding for genetic products or parts thereof, in addition to the use thereof. The invention also relates to the polypeptides obtained according to said sequences and to the use thereof.
PCT/DE1999/001178 1998-04-17 1999-04-15 Human nucleic acid sequences, increased expression thereof in uterus myoma tissue WO1999054448A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000544780A JP2002512024A (en) 1998-04-17 1999-04-15 Human nucleic acid sequences from fibroid tissue
EP99927686A EP1080188A2 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences of uterus myoma tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19817947A DE19817947A1 (en) 1998-04-17 1998-04-17 New nucleic acid sequences expressed in uterine myoma, and derived polypeptides, for treatment of uterine carcinoma and identification of therapeutic agents
DE19817947.2 1998-04-17

Publications (2)

Publication Number Publication Date
WO1999054448A2 WO1999054448A2 (en) 1999-10-28
WO1999054448A3 true WO1999054448A3 (en) 2000-07-06

Family

ID=7865425

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001178 WO1999054448A2 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences, increased expression thereof in uterus myoma tissue

Country Status (4)

Country Link
EP (1) EP1080188A2 (en)
JP (1) JP2002512024A (en)
DE (1) DE19817947A1 (en)
WO (1) WO1999054448A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4004200A (en) * 1999-02-26 2000-09-14 Zymogenetics Inc. Mammalian alpha-helical protein, zsig83
AU1486801A (en) * 1999-11-15 2001-05-30 Curagen Corporation Novel growth factor polypeptides and nucleic acids encoding same
WO2002024867A2 (en) * 2000-09-22 2002-03-28 University Of Aarhus Novel compositions and methods for lymphoma and leukemia
US20060063230A1 (en) 2000-12-27 2006-03-23 Roman Naworth Sulfatases and methods of use thereof
WO2003006688A2 (en) * 2001-07-13 2003-01-23 University Of Aarhus Methods for diagnosis and treatment of diseases associated with altered expression of gnas
AU2002337442A1 (en) * 2001-09-24 2003-04-07 University Of Aarhus Novel compositions and methods for diagnosis and treatment of lymphoma and leukemia

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BONFIELD, J. ET AL.: "A new DNA sequence assembly program", NUCLEIC ACIDS RESEARCH, vol. 23, 1995, pages 4992 - 4999, XP000872808 *
COLLINS, J.: "Phage display", ANNUAL REPORT IN COMBINATORIYL CHEMISTRY AND MOLECULAR DIVERSITY, vol. 1, - 1997, pages 210 - 262, XP000770016 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002128940, Database accession no. AA135168 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002128941, Database accession no. AA338040 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002128942, Database accession no. AA020869 *
LESSL, M. ET AL.: "Comparative messenger ribonucleic acid analysis of immediate early genes and sex steroid receptors in human leiomyoma and healthy myometrium", THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, vol. 82, no. 8, 1997, pages 2596 - 2600, XP002128938 *
SCHMITT, A.O. ET AL.: "Exhaustive mining of EST libraries for genes differentially expressed in normal and tumor tissue", NUCLEIC ACIDS RESEARCH, vol. 27, no. 21, 1 November 1999 (1999-11-01), pages 4251 - 4260, XP000872807 *
SCHULER, G.D.: "Sequence mapping by electronic PCR", GENOME RESEARCH, vol. 7, - 1997, pages 541 - 550, XP002127628 *
SINGH, M. ET AL.: "Decreased expression of functional human chorionic gonadotropin/ luteinizing hormone receptor gene in human uterine leiomyomas", BIOLOGY OF REPRODUCTION, vol. 53, 1995, pages 591 - 597, XP002128937 *

Also Published As

Publication number Publication date
EP1080188A2 (en) 2001-03-07
DE19817947A1 (en) 1999-10-28
WO1999054448A2 (en) 1999-10-28
JP2002512024A (en) 2002-04-23

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