WO1999006439A3 - 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM - Google Patents

5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM Download PDF

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Publication number
WO1999006439A3
WO1999006439A3 PCT/IB1998/001233 IB9801233W WO9906439A3 WO 1999006439 A3 WO1999006439 A3 WO 1999006439A3 IB 9801233 W IB9801233 W IB 9801233W WO 9906439 A3 WO9906439 A3 WO 9906439A3
Authority
WO
WIPO (PCT)
Prior art keywords
ests
secreted proteins
endoderm
proteins expressed
sequences
Prior art date
Application number
PCT/IB1998/001233
Other languages
French (fr)
Other versions
WO1999006439A2 (en
Inventor
Milne Edwards Jean-Bapti Dumas
Aymeric Duclert
Bruno Lacroix
Original Assignee
Genset Sa
Dumas Milne Edwards Jean Bapti
Aymeric Duclert
Bruno Lacroix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset Sa, Dumas Milne Edwards Jean Bapti, Aymeric Duclert, Bruno Lacroix filed Critical Genset Sa
Priority to CA002296398A priority Critical patent/CA2296398A1/en
Priority to AU85552/98A priority patent/AU8555298A/en
Priority to JP2000505194A priority patent/JP2001512005A/en
Priority to EP98936591A priority patent/EP0994899A2/en
Publication of WO1999006439A2 publication Critical patent/WO1999006439A2/en
Publication of WO1999006439A3 publication Critical patent/WO1999006439A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4728—Calcium binding proteins, e.g. calmodulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

The sequences of 5' ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5' ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5' ESTs. The 5' ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5' ESTs. The 5' ESTs may also be used to design expression vectors and secretion vectors.
PCT/IB1998/001233 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM WO1999006439A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002296398A CA2296398A1 (en) 1997-08-01 1998-07-31 5' ests for secreted proteins expressed in endoderm
AU85552/98A AU8555298A (en) 1997-08-01 1998-07-31 5' ests for secreted proteins expressed in endoderm
JP2000505194A JP2001512005A (en) 1997-08-01 1998-07-31 5'EST of secreted protein expressed in endoderm
EP98936591A EP0994899A2 (en) 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90446897A 1997-08-01 1997-08-01
US08/904,468 1997-08-01

Publications (2)

Publication Number Publication Date
WO1999006439A2 WO1999006439A2 (en) 1999-02-11
WO1999006439A3 true WO1999006439A3 (en) 1999-04-08

Family

ID=25419217

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1998/001233 WO1999006439A2 (en) 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM

Country Status (5)

Country Link
EP (1) EP0994899A2 (en)
JP (1) JP2001512005A (en)
AU (1) AU8555298A (en)
CA (1) CA2296398A1 (en)
WO (1) WO1999006439A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU724460B2 (en) * 1996-11-27 2000-09-21 Schering Corporation Mammalian chemokines
EP1352962A1 (en) * 1997-03-07 2003-10-15 Human Genome Sciences, Inc. 186 human secreted proteins
US20030054987A1 (en) * 1997-06-16 2003-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20020102542A1 (en) * 1997-10-07 2002-08-01 Daikichi Fukushima Polypeptide, cdna encoding the polypeptide, and use of the both
US6548633B1 (en) 1998-12-22 2003-04-15 Genset, S.A. Complementary DNA's encoding proteins with signal peptides
US6441131B1 (en) 1997-12-22 2002-08-27 Ono Pharmaceutical Co., Ltd. Peptides, method for assaying human pepsinogen II or human pepsin II, and assaying kit
JPH11187882A (en) * 1997-12-26 1999-07-13 Ono Pharmaceut Co Ltd Novel polypeptide, its production, cdna coding for the same polypeptide, vector comprising the same cdna, host cell transformed by the same vector, antibody of the same polypeptide, and pharmaceutical composition containing the polypeptide of antibody
US6306653B1 (en) * 1998-01-20 2001-10-23 Codon Diagnostics, Llc Detection and treatment of breast disease
AU5312699A (en) * 1998-06-25 2000-01-10 Millennium Pharmaceuticals, Inc. Novel mp-7 protein and nucleic acid molecules and uses therefor
US7083793B2 (en) 1999-02-26 2006-08-01 Millennium Pharmaceuticals, Inc. Tango 243 polypeptides and uses thereof
AU3382800A (en) * 1999-02-26 2000-09-14 Millennium Pharmaceuticals, Inc. Secreted proteins and uses thereof
US6277574B1 (en) * 1999-04-09 2001-08-21 Incyte Genomics, Inc. Genes associated with diseases of the kidney
US6262247B1 (en) * 1999-08-30 2001-07-17 Incyte Genomics, Inc. Polycyclic aromatic hydrocarbon induced molecules
JP3964678B2 (en) 1999-10-28 2007-08-22 アジェンシス，インコーポレイテッド 36P6D5: Secretory tumor antigen
FR2800750B1 (en) * 1999-11-05 2003-01-31 Centre Nat Rech Scient MEMBRANE PROTEINS CTL (CHOLINE TRANSPORTER LIKE) INVOLVED IN THE TRANSPORT OF CHOLINE
US6833241B2 (en) 2000-03-23 2004-12-21 Novartis Mammary gland chemokine
AU2001264819A1 (en) * 2000-05-26 2001-12-11 Indiana University Advanced Research And Technology Institute Placc, a novel human c-c chemokine isolated from placenta
US7927597B2 (en) 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
US7736654B2 (en) 2001-04-10 2010-06-15 Agensys, Inc. Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers
WO2012170977A1 (en) * 2011-06-10 2012-12-13 President And Fellows Of Harvard College Modulation of pancreatic beta cell proliferation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0625572A1 (en) * 1992-09-25 1994-11-23 The Kanagawa Academy Of Science And Technology Foundation PROCESS FOR SYNTHESIZING COMPLETE-LENGTH cDNA, PROCESS FOR PRODUCING INTERMEDIATE THEREFOR, AND PROCESS FOR PRODUCING RECOMBINANT VECTOR CONTAINING COMPLETE-LENGTH cDNA
WO1996034981A2 (en) * 1995-05-02 1996-11-07 Genset Sa METHOD FOR THE SPECIFIC COUPLING OF THE CAP OF THE EXTREMITY 5' OF A FRAGMENT mRNA AND PREPARATION OF mRNA AND COMPLETE cDNA
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby
WO1998042738A1 (en) * 1997-03-21 1998-10-01 Human Genome Sciences, Inc. 87 human secreted proteins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0625572A1 (en) * 1992-09-25 1994-11-23 The Kanagawa Academy Of Science And Technology Foundation PROCESS FOR SYNTHESIZING COMPLETE-LENGTH cDNA, PROCESS FOR PRODUCING INTERMEDIATE THEREFOR, AND PROCESS FOR PRODUCING RECOMBINANT VECTOR CONTAINING COMPLETE-LENGTH cDNA
WO1996034981A2 (en) * 1995-05-02 1996-11-07 Genset Sa METHOD FOR THE SPECIFIC COUPLING OF THE CAP OF THE EXTREMITY 5' OF A FRAGMENT mRNA AND PREPARATION OF mRNA AND COMPLETE cDNA
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby
WO1998042738A1 (en) * 1997-03-21 1998-10-01 Human Genome Sciences, Inc. 87 human secreted proteins

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
ASAKURA K. ET AL.: "A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens", JOURNAL OF NEUROIMMUNOLOGY, vol. 65, no. 1, March 1996 (1996-03-01), pages 11 - 19, XP002081171 *
CARNINCI P. ET AL.: "High-efficiency full-length cDNA cloning by biotinylated CAP trapper", GENOMICS, vol. 37, no. 3, 1 November 1996 (1996-11-01), pages 327 - 336, XP002081729 *
Database EMBL Emest15, Entry MM68132 Accession number W70681 19 June 1996 81% identity with Seq.ID:38 nt.11-352 *
Database EMBL Emest15, Entry MM70733 Accession number W70707 19 June 1996 82% identity with Seq.ID:38 nt.36-352 *
Database EMBL Emest15, Entry MMA28649 Accession number AA028649 17 August 1996 83% identity with Seq.ID:38 nt.26-352 *
Database EMBL Emest7, Entry HS1150166 Accession number AA232452 6 March 1997 94% identity with Seq.ID:38 nt.39-352 *
HEIJNE VON G.: "A new method for predicting signal sequence cleavage sites", NUCLEIC ACIDS RESEARCH, vol. 14, no. 11, 1986, pages 4683 - 4690, XP002053954 *
KATO S. ET AL.: "Construction of a human full-length cDNA bank", GENE, vol. 150, 1994, pages 243 - 250, XP002081364 *
OZAWA M.: "Cloning of a human homologue of mouse reticulocalbin reveals conservation of structural domains in the novel endoplasmic reticulum resident Ca2+-binding protein with multiple EF-hand motifs", JOURNAL OF BIOCHEMISTRY, vol. 117, 1995, pages 1113 - 1119, XP002070128 *
SCHÄFER B.W. AND HEIZMANN C.W.: "The S100 family of EF-hand calcium-binding proteins: functions and pathology", TIBS TRENDS IN BIOCHEMICAL SCIENCES, vol. 21, no. 4, April 1996 (1996-04-01), pages 134-140, XP004050923 *
TASHIRO K. ET AL.: "Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins", SCIENCE, vol. 261, 30 July 1993 (1993-07-30), pages 600 - 603, XP000673204 *
YOKOYAMA-KOBAYASHI M. ET AL.: "A signal sequence detection system using secreted protease activity as an indicator", GENE, vol. 163, 1995, pages 193 - 196, XP002053953 *

Also Published As

Publication number Publication date
AU8555298A (en) 1999-02-22
CA2296398A1 (en) 1999-02-11
WO1999006439A2 (en) 1999-02-11
EP0994899A2 (en) 2000-04-26
JP2001512005A (en) 2001-08-21

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