WO1998050773A3 - Biocapteur en porte-a-faux - Google Patents
Biocapteur en porte-a-faux Download PDFInfo
- Publication number
- WO1998050773A3 WO1998050773A3 PCT/US1998/009338 US9809338W WO9850773A3 WO 1998050773 A3 WO1998050773 A3 WO 1998050773A3 US 9809338 W US9809338 W US 9809338W WO 9850773 A3 WO9850773 A3 WO 9850773A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microbeam
- biosensor
- microcantilever
- microcantilever biosensor
- micrometer
- Prior art date
Links
- 230000008021 deposition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/02—Analysing fluids
- G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G3/00—Weighing apparatus characterised by the use of elastically-deformable members, e.g. spring balances
- G01G3/12—Weighing apparatus characterised by the use of elastically-deformable members, e.g. spring balances wherein the weighing element is in the form of a solid body stressed by pressure or tension during weighing
- G01G3/13—Weighing apparatus characterised by the use of elastically-deformable members, e.g. spring balances wherein the weighing element is in the form of a solid body stressed by pressure or tension during weighing having piezoelectric or piezoresistive properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2291/00—Indexing codes associated with group G01N29/00
- G01N2291/02—Indexing codes associated with the analysed material
- G01N2291/025—Change of phase or condition
- G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
- G01N2291/0257—Adsorption, desorption, surface mass change, e.g. on biosensors with a layer containing at least one organic compound
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85275897A | 1997-05-08 | 1997-05-08 | |
US08/852,758 | 1997-05-08 | ||
US5422398A | 1998-04-02 | 1998-04-02 | |
US09/054,223 | 1998-04-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998050773A2 WO1998050773A2 (fr) | 1998-11-12 |
WO1998050773A3 true WO1998050773A3 (fr) | 1999-04-15 |
Family
ID=26732773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/009338 WO1998050773A2 (fr) | 1997-05-08 | 1998-05-07 | Biocapteur en porte-a-faux |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO1998050773A2 (fr) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6576478B1 (en) * | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
US6682942B1 (en) | 1998-07-14 | 2004-01-27 | Zyomyx, Inc. | Microdevices for screening biomolecules |
US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
GB9819319D0 (en) * | 1998-09-05 | 1998-10-28 | Aea Technology Plc | Assay of chemical binding |
US6289717B1 (en) * | 1999-03-30 | 2001-09-18 | U. T. Battelle, Llc | Micromechanical antibody sensor |
FR2795515B1 (fr) * | 1999-06-08 | 2004-02-20 | Commissariat Energie Atomique | Plate-forme d'analyse chimique ou biologique a microbalances, dispositif et procede d'analyse utilisant la plate-forme |
DE60012962T2 (de) | 1999-11-03 | 2005-08-11 | International Business Machines Corp. | Sensoren und wandler mit freitragendem ausleger |
EP1297010A2 (fr) * | 2000-06-23 | 2003-04-02 | Bioelastics Research, Ltd. | Nanodispositifs et biocapteurs bioelastomeres |
GB2369436A (en) * | 2000-07-28 | 2002-05-29 | Marconi Applied Techn Ltd | Chemical sensing micro-mechanical cantilever |
DE60123818T2 (de) | 2000-08-09 | 2007-08-23 | California Institute Of Technology, Pasadena | Nanoelektromechanische vorrichtung zur durchführung biochemischer analysen |
US7375321B2 (en) | 2000-08-09 | 2008-05-20 | California Institute Of Technology | Dynamics bionems sensors and arrays of bionems sensor immersed in fluids |
DE60032772T2 (de) | 2000-09-27 | 2007-11-08 | Stmicroelectronics S.R.L., Agrate Brianza | Integrierter chemischer Mikroreaktor mit thermisch isolierten Messelektroden und Verfahren zu dessen Herstellung |
EP1202046A1 (fr) * | 2000-10-25 | 2002-05-02 | Abb Research Ltd. | Méthode et appareil pour déterminer des espèces biologiques |
US8372139B2 (en) | 2001-02-14 | 2013-02-12 | Advanced Bio Prosthetic Surfaces, Ltd. | In vivo sensor and method of making same |
DE10113254A1 (de) | 2001-03-19 | 2002-10-02 | Infineon Technologies Ag | Mikromechanik-Sensorelement und elektrische Schaltungsanordnung |
US20030116552A1 (en) | 2001-12-20 | 2003-06-26 | Stmicroelectronics Inc. | Heating element for microfluidic and micromechanical applications |
WO2003062135A1 (fr) * | 2002-01-24 | 2003-07-31 | Cantion A/S | Capteur |
DE10209245B4 (de) * | 2002-03-04 | 2005-12-22 | Concentris Gmbh | Vorrichtung und Verfahren zur Detektion von Mikroorganismen |
WO2003104784A1 (fr) * | 2002-06-07 | 2003-12-18 | Cantion A/S | Capteur cantilever a ecran de courant et son procede de production |
JP4329322B2 (ja) * | 2002-10-04 | 2009-09-09 | ソニー株式会社 | 相互反応作用検出方法及びバイオアッセイ装置、並びにバイオアッセイ用基板 |
US7344678B2 (en) | 2002-11-15 | 2008-03-18 | The Regents Of The University Of California | Composite sensor membrane |
DE10333972B4 (de) * | 2003-07-25 | 2014-04-10 | Robert Bosch Gmbh | Verfahren zum Herstellen eines Sensors für biochemische Messungen |
JP4247554B2 (ja) * | 2003-07-30 | 2009-04-02 | 独立行政法人理化学研究所 | メカノケミカル式センサー |
KR100613398B1 (ko) * | 2003-11-25 | 2006-08-17 | 한국과학기술연구원 | 캔틸레버 센서형 분석 시스템, 제조 방법 및 이를 이용한극미세 물질 감지 방법 |
US7497133B2 (en) | 2004-05-24 | 2009-03-03 | Drexel University | All electric piezoelectric finger sensor (PEFS) for soft material stiffness measurement |
EP1618955B1 (fr) | 2004-07-19 | 2010-12-22 | STMicroelectronics Srl | Dispositif pour la détection de molécules biologiques avec taux de détection augmenté et procédé de détection rapide de molécules biologiques |
DE102004046685B3 (de) * | 2004-09-24 | 2006-06-29 | Concentris Gmbh | Messzelle und Verfahren für die Flüssigkeitsanalyse |
JP2006153831A (ja) * | 2004-10-27 | 2006-06-15 | Mitsubishi Chemicals Corp | カンチレバーセンサ、センサシステム及び検体液中の検出対象物質の検出方法 |
WO2006076507A2 (fr) * | 2005-01-14 | 2006-07-20 | Massachusetts Institute Of Technology | Detecteur auto-active |
JP2006214744A (ja) * | 2005-02-01 | 2006-08-17 | Gunma Univ | バイオセンサ及びバイオセンサチップ |
DE602006000724T2 (de) | 2005-02-05 | 2009-04-23 | Samsung Electronics Co., Ltd., Suwon | Sensorschalter und seine Verwendung in einem Nachweisverfahren |
GB2432907A (en) * | 2005-12-05 | 2007-06-06 | Univ Basel | Device for detecting the characteristics of organic molecules |
US20080311679A1 (en) * | 2005-12-23 | 2008-12-18 | Koninklijke Philips Electronics N.V. | Biosensor Device |
ES2412887T3 (es) | 2006-01-23 | 2013-07-12 | Drexel University | Sensor piezoeléctrico en voladizo de autodetección, autoexcitable |
US8171795B1 (en) | 2006-01-23 | 2012-05-08 | Drexel University | Self-exciting, self-sensing piezoelectric cantilever sensor for detection of airborne analytes directly in air |
WO2007133619A1 (fr) | 2006-05-10 | 2007-11-22 | Drexel University | ContrÔle molÉculaire du recouvrement d'une surface |
JP5219014B2 (ja) * | 2006-10-24 | 2013-06-26 | 独立行政法人科学技術振興機構 | 糖類の直接的な表面固定化方法、糖類とタンパク質との間の相互作用を検出する方法 |
US8481335B2 (en) | 2006-11-27 | 2013-07-09 | Drexel University | Specificity and sensitivity enhancement in cantilever sensing |
US7992431B2 (en) | 2006-11-28 | 2011-08-09 | Drexel University | Piezoelectric microcantilevers and uses in atomic force microscopy |
EP2100125A4 (fr) | 2006-11-28 | 2012-02-15 | Univ Drexel | Capteurs de microporte-à-faux piézoélectriques pour la biodétection |
DE102007059977B4 (de) * | 2006-12-12 | 2011-03-31 | Concentris Gmbh | Vorrichtung zum Betrieb eines mikromechanischen Federbalkens und Messanordnung mit einem solchen Federbalken |
US7671511B2 (en) | 2006-12-12 | 2010-03-02 | Concentris Gmbh | System for oscillating a micromechanical cantilever |
US8456150B2 (en) | 2007-02-01 | 2013-06-04 | Drexel University | Hand-held phase-shift detector for sensor applications |
US8512947B2 (en) | 2007-02-16 | 2013-08-20 | Drexel University | Detection of nucleic acids using a cantilever sensor |
WO2008101199A1 (fr) | 2007-02-16 | 2008-08-21 | Drexel University | Augmentation de la sensibilité d'un capteur d'assemblage grâce à des liaisons spécifiques |
US7993854B2 (en) | 2007-05-30 | 2011-08-09 | Drexel University | Detection and quantification of biomarkers via a piezoelectric cantilever sensor |
US8241569B2 (en) | 2007-11-23 | 2012-08-14 | Drexel University | Lead-free piezoelectric ceramic films and a method for making thereof |
US8236508B2 (en) | 2008-01-29 | 2012-08-07 | Drexel University | Detecting and measuring live pathogens utilizing a mass detection device |
WO2009126378A2 (fr) | 2008-03-11 | 2009-10-15 | Drexel University | Sensibilité de détection améliorée avec capteurs micro-cantilevers piézoélectriques |
CN102066928B (zh) | 2008-05-16 | 2015-08-05 | 德瑞索大学 | 评估组织的***和方法 |
IT1392736B1 (it) | 2008-12-09 | 2012-03-16 | St Microelectronics Rousset | Dispositivo a microbilancia torsionale integrata in tecnologia mems e relativo processo di fabbricazione |
US8722427B2 (en) | 2009-10-08 | 2014-05-13 | Drexel University | Determination of dissociation constants using piezoelectric microcantilevers |
US8479585B2 (en) | 2010-09-08 | 2013-07-09 | Micropen Technologies Corporation | Pressure sensing or force generating device |
US10266397B2 (en) | 2014-08-13 | 2019-04-23 | University Of South Carolina | III-V nitride resonate structure based photoacoustic sensor |
EP3322410A4 (fr) * | 2015-07-14 | 2019-02-20 | Nanosniff Technologies Pvt. Ltd. | Procédé d'immobilisation d'une ou plusieurs biomolécule(s) réceptrices sur une ou plusieurs surface(s) solide(s) |
US20170089865A1 (en) * | 2015-09-25 | 2017-03-30 | Intel Corporation | Integrated Molecular Sensor System |
DE102021107254A1 (de) | 2021-03-23 | 2022-09-29 | digid GmbH | Digitale Sensorvorrichtung zur Detektion eines Analyten in einer Probe |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4789804A (en) * | 1985-09-17 | 1988-12-06 | Seiko Instruments & Electronics Ltd. | Analytical device and method utilizing a piezoelectric crystal biosensor |
US4906440A (en) * | 1986-09-09 | 1990-03-06 | The United States Of America As Represented By The Secretary Of The Air Force | Sensor for detecting chemicals |
US5209119A (en) * | 1990-12-12 | 1993-05-11 | Regents Of The University Of Minnesota | Microdevice for sensing a force |
WO1994005414A1 (fr) * | 1992-08-31 | 1994-03-17 | The Regents Of The University Of California | Reacteur microfabrique |
EP0657737A2 (fr) * | 1993-12-13 | 1995-06-14 | Hewlett-Packard Company | Méthode et réactifs pour attacher les analytes chimiques à une surface d'une substrate, et dispositifs analytiques et techniques diagnostiques apparentes |
US5445008A (en) * | 1994-03-24 | 1995-08-29 | Martin Marietta Energy Systems, Inc. | Microbar sensor |
US5589136A (en) * | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
US5593838A (en) * | 1994-11-10 | 1997-01-14 | David Sarnoff Research Center, Inc. | Partitioned microelectronic device array |
US5719324A (en) * | 1995-06-16 | 1998-02-17 | Lockheed Martin Energy Systems, Inc. | Microcantilever sensor |
-
1998
- 1998-05-07 WO PCT/US1998/009338 patent/WO1998050773A2/fr active Application Filing
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4789804A (en) * | 1985-09-17 | 1988-12-06 | Seiko Instruments & Electronics Ltd. | Analytical device and method utilizing a piezoelectric crystal biosensor |
US4906440A (en) * | 1986-09-09 | 1990-03-06 | The United States Of America As Represented By The Secretary Of The Air Force | Sensor for detecting chemicals |
US5209119A (en) * | 1990-12-12 | 1993-05-11 | Regents Of The University Of Minnesota | Microdevice for sensing a force |
WO1994005414A1 (fr) * | 1992-08-31 | 1994-03-17 | The Regents Of The University Of California | Reacteur microfabrique |
US5674742A (en) * | 1992-08-31 | 1997-10-07 | The Regents Of The University Of California | Microfabricated reactor |
EP0657737A2 (fr) * | 1993-12-13 | 1995-06-14 | Hewlett-Packard Company | Méthode et réactifs pour attacher les analytes chimiques à une surface d'une substrate, et dispositifs analytiques et techniques diagnostiques apparentes |
US5445008A (en) * | 1994-03-24 | 1995-08-29 | Martin Marietta Energy Systems, Inc. | Microbar sensor |
US5593838A (en) * | 1994-11-10 | 1997-01-14 | David Sarnoff Research Center, Inc. | Partitioned microelectronic device array |
US5719324A (en) * | 1995-06-16 | 1998-02-17 | Lockheed Martin Energy Systems, Inc. | Microcantilever sensor |
US5589136A (en) * | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
Non-Patent Citations (1)
Title |
---|
MIHAILOVIC R.E. ET AL: "Measurement of the elastic stress of thin films deposited on gallium arsenide", J.VAC.SCI.TECHNOL.A., vol. 14, no. 4, 1996, US, pages 2483 - 2487, XP002091883 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998050773A2 (fr) | 1998-11-12 |
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