WO1998004508A1 - NOVEL p-TERPHENYL COMPOUNDS - Google Patents
NOVEL p-TERPHENYL COMPOUNDS Download PDFInfo
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- WO1998004508A1 WO1998004508A1 PCT/JP1997/002635 JP9702635W WO9804508A1 WO 1998004508 A1 WO1998004508 A1 WO 1998004508A1 JP 9702635 W JP9702635 W JP 9702635W WO 9804508 A1 WO9804508 A1 WO 9804508A1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/12—Polycyclic non-condensed hydrocarbons
- C07C15/14—Polycyclic non-condensed hydrocarbons all phenyl groups being directly linked
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- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
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- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
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- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/76—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
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- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/27—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
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- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/80—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
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- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/38—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
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- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/60—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by carboxyl groups
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- C07C255/00—Carboxylic acid nitriles
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- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
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- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
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- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
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- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/02—Compounds containing any of the groups, e.g. carbazates
- C07C281/04—Compounds containing any of the groups, e.g. carbazates the other nitrogen atom being further doubly-bound to a carbon atom
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- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
- C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
- C07C281/10—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to an acyclic carbon atom or to a carbon atom of a ring other than a six-membered aromatic ring
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- C07C307/04—Diamides of sulfuric acids
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- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
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- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
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- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
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- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
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- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C327/42—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
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- C07C43/235—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring and to a carbon atom of a ring other than a six-membered aromatic ring
- C07C43/253—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring and to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
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- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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- C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
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Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
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DE69726745T DE69726745T2 (de) | 1996-07-31 | 1997-07-30 | NEUE p-TERPHENYL VERBINDUNGEN |
IL12819097A IL128190A0 (en) | 1996-07-31 | 1997-07-30 | Novel p-terphenyl compounds |
CA002261339A CA2261339A1 (en) | 1996-07-31 | 1997-07-30 | Novel p-terphenyl compounds |
IL14630197A IL146301A0 (en) | 1996-07-31 | 1997-07-30 | Novel p-terphenyl compounds |
JP50869898A JP4008498B2 (ja) | 1996-07-31 | 1997-07-30 | 新規パラテルフェニル化合物 |
IL14627997A IL146279A0 (en) | 1996-07-31 | 1997-07-30 | Novel p-terphenyl compounds |
DK97933837T DK0933346T3 (da) | 1996-07-31 | 1997-07-30 | Nye p-terphenylforbindelser |
US09/214,277 US7101915B1 (en) | 1996-07-31 | 1997-07-30 | P-terphenyl compounds |
BR9710780A BR9710780A (pt) | 1996-07-31 | 1997-07-30 | Novos compostos de para-terefenila |
AT97933837T ATE256092T1 (de) | 1996-07-31 | 1997-07-30 | Neue p-terphenyl verbindungen |
NZ333688A NZ333688A (en) | 1996-07-31 | 1997-07-30 | p-terphenyl compounds suitable as IgE production suppressors |
PL97331497A PL331497A1 (en) | 1996-07-31 | 1997-07-30 | Novel para-terphenyl compounds |
EP97933837A EP0933346B1 (en) | 1996-07-31 | 1997-07-30 | NOVEL p-TERPHENYL COMPOUNDS |
AU37067/97A AU729320B2 (en) | 1996-07-31 | 1997-07-30 | Novel para-terphenyl compounds |
NO19990415A NO315369B1 (no) | 1996-07-31 | 1999-01-28 | p-terfenylforbindelser, fremgangsmåter for deres fremstilling, preparat/middel inneholdende en slik forbindelse, samt deres anvendelse |
US10/705,505 US7074836B1 (en) | 1996-07-31 | 2003-11-12 | Para-terphenyl compounds |
US10/704,876 US7220783B2 (en) | 1996-07-31 | 2003-11-12 | Para-terphenyl compounds |
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JP8/201859 | 1996-07-31 | ||
JP20185996 | 1996-07-31 | ||
JP28778296 | 1996-10-30 | ||
JP8/287782 | 1996-10-30 | ||
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JP9/86085 | 1997-03-18 |
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US09214277 A-371-Of-International | 1997-07-30 | ||
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US10/704,876 Division US7220783B2 (en) | 1996-07-31 | 2003-11-12 | Para-terphenyl compounds |
Publications (1)
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WO1998004508A1 true WO1998004508A1 (en) | 1998-02-05 |
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PCT/JP1997/002635 WO1998004508A1 (en) | 1996-07-31 | 1997-07-30 | NOVEL p-TERPHENYL COMPOUNDS |
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US (3) | US7101915B1 (ja) |
EP (1) | EP0933346B1 (ja) |
JP (1) | JP4008498B2 (ja) |
KR (1) | KR100338855B1 (ja) |
CN (1) | CN1232443A (ja) |
AT (1) | ATE256092T1 (ja) |
AU (1) | AU729320B2 (ja) |
BR (1) | BR9710780A (ja) |
CA (1) | CA2261339A1 (ja) |
CZ (1) | CZ30399A3 (ja) |
DE (1) | DE69726745T2 (ja) |
DK (1) | DK0933346T3 (ja) |
ES (1) | ES2212119T3 (ja) |
IL (1) | IL128190A0 (ja) |
NO (1) | NO315369B1 (ja) |
NZ (1) | NZ333688A (ja) |
PL (1) | PL331497A1 (ja) |
PT (1) | PT933346E (ja) |
RU (1) | RU2200730C2 (ja) |
TW (1) | TW510895B (ja) |
WO (1) | WO1998004508A1 (ja) |
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WO2001007401A1 (fr) * | 1999-07-23 | 2001-02-01 | Shionogi & Co., Ltd. | Composes tricycliques et compositions medicamenteuses les contenant |
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WO2001074331A1 (fr) * | 2000-04-04 | 2001-10-11 | Shionogi & Co., Ltd. | Compositions huileuses contenant des medicaments solubles dans des graisses |
WO2001076582A1 (fr) * | 2000-04-05 | 2001-10-18 | Shionogi & Co., Ltd. | Micro-emulsions huile dans eau contenant des composes tricycliques ou des preconcentres de ceux-ci |
WO2002057216A1 (fr) * | 2001-01-18 | 2002-07-25 | Shionogi & Co., Ltd. | Composes de terphenyle supportant des groupes amino substitues |
US6706703B2 (en) | 2001-06-29 | 2004-03-16 | Kowa Co., Ltd. | Bis(5-aryl-2-pyridyl) derivatives |
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CN113214056B (zh) * | 2021-04-16 | 2023-08-29 | 子辰海洋医药科技(上海)有限公司 | 联苯类化合物和二萜类化合物及其制备方法与应用 |
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- 1997-07-30 AU AU37067/97A patent/AU729320B2/en not_active Ceased
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- 1997-07-30 RU RU99103617/04A patent/RU2200730C2/ru not_active IP Right Cessation
- 1997-07-30 ES ES97933837T patent/ES2212119T3/es not_active Expired - Lifetime
- 1997-07-30 IL IL12819097A patent/IL128190A0/xx unknown
- 1997-07-30 DK DK97933837T patent/DK0933346T3/da active
- 1997-07-30 PL PL97331497A patent/PL331497A1/xx unknown
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US7008954B1 (en) | 1999-07-23 | 2006-03-07 | Shionogi & Co., Ltd. | Th2 differentiation inhibitors |
WO2001007032A1 (fr) * | 1999-07-23 | 2001-02-01 | Shionogi & Co., Ltd. | Inhibiteurs de differenciation th2 |
EP1206935A1 (en) * | 1999-07-23 | 2002-05-22 | Shionogi & Co., Ltd. | Th2 differentiation inhibitors |
AU763976B2 (en) * | 1999-07-23 | 2003-08-07 | Shionogi & Co., Ltd. | Th2 differentiation inhibitors |
WO2001007401A1 (fr) * | 1999-07-23 | 2001-02-01 | Shionogi & Co., Ltd. | Composes tricycliques et compositions medicamenteuses les contenant |
EP1206935A4 (en) * | 1999-07-23 | 2008-07-30 | Shionogi & Co | TH2 DIFFERENTIAL INHIBITION |
WO2001074331A1 (fr) * | 2000-04-04 | 2001-10-11 | Shionogi & Co., Ltd. | Compositions huileuses contenant des medicaments solubles dans des graisses |
WO2001076582A1 (fr) * | 2000-04-05 | 2001-10-18 | Shionogi & Co., Ltd. | Micro-emulsions huile dans eau contenant des composes tricycliques ou des preconcentres de ceux-ci |
WO2002057216A1 (fr) * | 2001-01-18 | 2002-07-25 | Shionogi & Co., Ltd. | Composes de terphenyle supportant des groupes amino substitues |
US6858600B2 (en) | 2001-05-08 | 2005-02-22 | Yale University | Proteomimetic compounds and methods |
US7312246B2 (en) | 2001-05-08 | 2007-12-25 | Yale University | Proteomimetic compounds and methods |
US6706703B2 (en) | 2001-06-29 | 2004-03-16 | Kowa Co., Ltd. | Bis(5-aryl-2-pyridyl) derivatives |
US7196101B2 (en) | 2001-06-29 | 2007-03-27 | Kowa Co., Ltd | Bis(5-aryl-2-pyridyl) derivatives |
US6890940B2 (en) | 2001-06-29 | 2005-05-10 | Kowa Co., Ltd. | Bis(2-aryl-5-pyridyl) derivatives |
WO2004080943A1 (ja) * | 2003-03-11 | 2004-09-23 | Ono Pharmaceutical Co., Ltd. | シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤 |
US8012971B2 (en) | 2005-04-28 | 2011-09-06 | Dainippon Sumitomo Pharma Co., Ltd. | Therapeutic agent for chronic obstructive pulmonary disease |
JP2009521527A (ja) * | 2005-12-30 | 2009-06-04 | エルジー・ケム・リミテッド | 遷移金属化合物およびその製造方法 |
US7173155B1 (en) * | 2006-01-12 | 2007-02-06 | Gwangju Institute Of Science And Technology | Terphenyl dihalide monomers having sulfonate groups and process for preparing the same |
US9546149B2 (en) | 2007-06-08 | 2017-01-17 | Mannkind Corporation | IRE-1α inhibitors |
US9241942B2 (en) | 2007-06-08 | 2016-01-26 | Mannkind Corporation | IRE-1α inhibitors |
US9981901B2 (en) | 2007-06-08 | 2018-05-29 | Fosun Orinove Pharmatech, Inc. | IRE-1α inhibitors |
JP5408660B2 (ja) * | 2007-09-04 | 2014-02-05 | 学校法人東京農業大学 | パラテルフェニル化合物、その薬理学的に許容される塩、その製造方法及び用途 |
US9199936B2 (en) | 2009-11-05 | 2015-12-01 | Fibrostatin Sociedad Limitada | GPBP inhibition using Q2 peptidomimetics |
JP2013510077A (ja) * | 2009-11-05 | 2013-03-21 | フィブロスタチン ソシエダ リミターダ | 擬似q2ペプチドを用いるgpbp抑制 |
US10544083B2 (en) | 2009-11-05 | 2020-01-28 | Universitat De València | GPBP inhibition using Q2 peptidomimetics |
WO2016114093A1 (ja) * | 2015-01-14 | 2016-07-21 | Jnc株式会社 | 重合性基を有する化合物、液晶組成物および液晶表示素子 |
CN107108453A (zh) * | 2015-01-14 | 2017-08-29 | 捷恩智株式会社 | 具有聚合性基的化合物、液晶组合物及液晶显示元件 |
CN107108453B (zh) * | 2015-01-14 | 2023-09-19 | 捷恩智株式会社 | 具有聚合性基的化合物、液晶组合物及液晶显示元件 |
CN105175241A (zh) * | 2015-08-28 | 2015-12-23 | 浙江工业大学 | 三联苯类化合物及其制备方法和应用 |
WO2018186365A1 (ja) * | 2017-04-03 | 2018-10-11 | 京都薬品工業株式会社 | リードスルー誘導剤およびその医薬用途 |
Also Published As
Publication number | Publication date |
---|---|
AU3706797A (en) | 1998-02-20 |
TW510895B (en) | 2002-11-21 |
ES2212119T3 (es) | 2004-07-16 |
RU2200730C2 (ru) | 2003-03-20 |
AU729320B2 (en) | 2001-02-01 |
PL331497A1 (en) | 1999-07-19 |
IL128190A0 (en) | 1999-11-30 |
KR100338855B1 (ko) | 2002-12-28 |
US7074836B1 (en) | 2006-07-11 |
NO315369B1 (no) | 2003-08-25 |
NZ333688A (en) | 2001-06-29 |
NO990415D0 (no) | 1999-01-28 |
BR9710780A (pt) | 1999-08-17 |
US20040127495A1 (en) | 2004-07-01 |
ATE256092T1 (de) | 2003-12-15 |
US7101915B1 (en) | 2006-09-05 |
JP4008498B2 (ja) | 2007-11-14 |
EP0933346A1 (en) | 1999-08-04 |
EP0933346B1 (en) | 2003-12-10 |
NO990415L (no) | 1999-03-26 |
KR20000029669A (ko) | 2000-05-25 |
EP0933346A4 (en) | 2000-12-06 |
CZ30399A3 (cs) | 1999-07-14 |
PT933346E (pt) | 2004-03-31 |
DE69726745T2 (de) | 2004-09-30 |
DK0933346T3 (da) | 2004-03-29 |
CN1232443A (zh) | 1999-10-20 |
DE69726745D1 (de) | 2004-01-22 |
US7220783B2 (en) | 2007-05-22 |
CA2261339A1 (en) | 1998-02-05 |
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