WO1997028826A3 - Contraceptive release systems with antibacterial and/or antiviral effect - Google Patents

Contraceptive release systems with antibacterial and/or antiviral effect Download PDF

Info

Publication number
WO1997028826A3
WO1997028826A3 PCT/DE1997/000321 DE9700321W WO9728826A3 WO 1997028826 A3 WO1997028826 A3 WO 1997028826A3 DE 9700321 W DE9700321 W DE 9700321W WO 9728826 A3 WO9728826 A3 WO 9728826A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibacterial
contraceptive
antiviral effect
release systems
compound
Prior art date
Application number
PCT/DE1997/000321
Other languages
German (de)
French (fr)
Other versions
WO1997028826A2 (en
Inventor
Klaus Stoeckemann
Arwed Cleve
Karin Hoffmann
Ulrich Koch
Original Assignee
Schering Ag
Klaus Stoeckemann
Arwed Cleve
Karin Hoffmann
Ulrich Koch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP97919251A priority Critical patent/EP0880364A2/en
Priority to EE9800239A priority patent/EE9800239A/en
Priority to AU23792/97A priority patent/AU2379297A/en
Priority to PL97328333A priority patent/PL328333A1/en
Application filed by Schering Ag, Klaus Stoeckemann, Arwed Cleve, Karin Hoffmann, Ulrich Koch filed Critical Schering Ag
Priority to IL12548197A priority patent/IL125481A0/en
Priority to BR9707416A priority patent/BR9707416A/en
Priority to EA199800714A priority patent/EA199800714A1/en
Priority to JP9528064A priority patent/JP2000506515A/en
Priority to APAP/P/1998/001306A priority patent/AP9801306A0/en
Priority to SK1070-98A priority patent/SK107098A3/en
Publication of WO1997028826A2 publication Critical patent/WO1997028826A2/en
Publication of WO1997028826A3 publication Critical patent/WO1997028826A3/en
Priority to IS4802A priority patent/IS4802A/en
Priority to BG102682A priority patent/BG102682A/en
Priority to NO983672A priority patent/NO983672L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

The invention relates to the combination of at least one compound with contraceptive effect and/or one compound with antibacterial and/or antiviral effect for incorporation/application to an intravaginal, intrauterine or intracervical release system. The invention also relates to the use of said release system.
PCT/DE1997/000321 1996-02-12 1997-02-11 Contraceptive release systems with antibacterial and/or antiviral effect WO1997028826A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
BR9707416A BR9707416A (en) 1996-02-12 1997-02-11 Contraceptive delivery systems with antibacterial and / or antiviral action
AU23792/97A AU2379297A (en) 1996-02-12 1997-02-11 Contraceptive release systems with antibacterial and/or antiviral effect
PL97328333A PL328333A1 (en) 1996-02-12 1997-02-11 Contraceptive releasing systems of antibacterial and/or antiviral activity
JP9528064A JP2000506515A (en) 1996-02-12 1997-02-11 Contraceptive release system with antibacterial and / or antiviral action
IL12548197A IL125481A0 (en) 1996-02-12 1997-02-11 Contraceptive release system with an antibacterial action and/or an antiviral action
EE9800239A EE9800239A (en) 1996-02-12 1997-02-11 Antibacterial and / or antiviral contraceptive release systems
EA199800714A EA199800714A1 (en) 1996-02-12 1997-02-11 Anti-bacterial and / or anti-viral anti-viral contraceptive systems
EP97919251A EP0880364A2 (en) 1996-02-12 1997-02-11 Contraceptive release systems with antibacterial and/or antiviral effect
APAP/P/1998/001306A AP9801306A0 (en) 1996-02-12 1997-02-11 Contraceptive release system with an antibacterial action and/or antiviral action.
SK1070-98A SK107098A3 (en) 1996-02-12 1997-02-11 Contraceptive release systems with antibacterial and/or antiviral effect
IS4802A IS4802A (en) 1996-02-12 1998-07-21 Contraceptive release system with bactericidal and / or antiviral activity
BG102682A BG102682A (en) 1996-02-12 1998-08-11 System for the release of contraceptives having bactericidal and/or antiviral effect
NO983672A NO983672L (en) 1996-02-12 1998-08-11 Prevention system with antibacterial and / or antiviral effect

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19606355.8 1996-02-12
DE19606355A DE19606355A1 (en) 1996-02-12 1996-02-12 Contraceptive release systems with antiviral and / or antibacterial effects

Publications (2)

Publication Number Publication Date
WO1997028826A2 WO1997028826A2 (en) 1997-08-14
WO1997028826A3 true WO1997028826A3 (en) 1997-10-16

Family

ID=7785948

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1997/000321 WO1997028826A2 (en) 1996-02-12 1997-02-11 Contraceptive release systems with antibacterial and/or antiviral effect

Country Status (21)

Country Link
EP (1) EP0880364A2 (en)
JP (1) JP2000506515A (en)
KR (1) KR19990082434A (en)
CN (1) CN1211193A (en)
AP (1) AP9801306A0 (en)
AU (1) AU2379297A (en)
BG (1) BG102682A (en)
BR (1) BR9707416A (en)
CA (1) CA2245920A1 (en)
CZ (1) CZ253298A3 (en)
DE (1) DE19606355A1 (en)
EA (1) EA199800714A1 (en)
EE (1) EE9800239A (en)
HU (1) HUP9901977A3 (en)
IL (1) IL125481A0 (en)
IS (1) IS4802A (en)
NO (1) NO983672L (en)
PL (1) PL328333A1 (en)
SK (1) SK107098A3 (en)
TR (1) TR199801551T2 (en)
WO (1) WO1997028826A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015176A2 (en) * 1998-09-10 2000-03-23 Magainin Pharmaceuticals, Inc. Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
AU2003213958A1 (en) * 2002-04-03 2003-10-13 Jencap Research Ltd. Female birth control method
DK1902017T3 (en) * 2005-06-24 2014-06-30 Biotron Ltd Antiviral acylguanidine compounds
DE102008006416A1 (en) * 2008-01-28 2009-07-30 Mayer, Thomas, Dr. med. Clindamycin or its salt, or a clindamycin-containing composition useful for the intracervical or endocervical treatment or prevention of bacterial vaginosis caused by anaerobic and gram positive aerobic germs
US20100120707A1 (en) * 2008-09-16 2010-05-13 Playtex Products, Llc Dosages for menstrual suppression, contraception, and hormone replacement therapy, and methods of administering same
FI20095563A (en) * 2009-05-20 2010-11-21 Bayer Schering Pharma Oy Vaginal delivery system
GB201203768D0 (en) * 2012-03-05 2012-04-18 John Richard W Medical device
ES2699003T3 (en) * 2014-06-28 2019-02-06 Laboratorios Andromaco S A Cerclage pessary containing prolonged-release, sustained-release progesterone, used for the prevention of premature births
CN105796572A (en) * 2014-08-25 2016-07-27 郭曙平 Contraceptive and preparation method thereof
CN109248140A (en) * 2017-07-14 2019-01-22 国家卫生计生委科学技术研究所 The preparation method and application of progesterone antibacterial pesseulum
EP3446664A1 (en) 2017-08-21 2019-02-27 Karl-Heinz Kurz Intrauterine device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2101533A1 (en) * 1970-01-15 1971-09-16 Biological Concepts Inc , New York, NY (V St A ) Device for the dosed delivery of medication
FR2250520A1 (en) * 1973-11-09 1975-06-06 Cournut Rene
US4180064A (en) * 1972-12-27 1979-12-25 Alza Corporation System for delivering agent to environment of use over prolonged time
GB2026320A (en) * 1978-07-25 1980-02-06 Gutnick Morton Devices for the prevention of venereal disease
US4393871A (en) * 1977-06-27 1983-07-19 Vli Corporation Vaginal device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034749A (en) * 1973-12-06 1977-07-12 Schering Aktiengesellschaft Intrauterine contraceptive device
US4578076A (en) * 1984-03-20 1986-03-25 The Population Council, Inc. Medicated intracervical and intrauterine devices
US5229423A (en) * 1992-03-06 1993-07-20 Albert Einstein College Of Medicine Of Yeshiva University Use of butylurea as a contraceptive agent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2101533A1 (en) * 1970-01-15 1971-09-16 Biological Concepts Inc , New York, NY (V St A ) Device for the dosed delivery of medication
US4180064A (en) * 1972-12-27 1979-12-25 Alza Corporation System for delivering agent to environment of use over prolonged time
FR2250520A1 (en) * 1973-11-09 1975-06-06 Cournut Rene
US4393871A (en) * 1977-06-27 1983-07-19 Vli Corporation Vaginal device
GB2026320A (en) * 1978-07-25 1980-02-06 Gutnick Morton Devices for the prevention of venereal disease

Also Published As

Publication number Publication date
CN1211193A (en) 1999-03-17
NO983672D0 (en) 1998-08-11
HUP9901977A2 (en) 1999-10-28
EP0880364A2 (en) 1998-12-02
EE9800239A (en) 1998-12-15
SK107098A3 (en) 1999-01-11
HUP9901977A3 (en) 2000-06-28
IS4802A (en) 1998-07-21
WO1997028826A2 (en) 1997-08-14
BG102682A (en) 1999-03-31
PL328333A1 (en) 1999-01-18
BR9707416A (en) 1999-05-25
EA199800714A1 (en) 1999-02-25
TR199801551T2 (en) 1998-11-23
JP2000506515A (en) 2000-05-30
IL125481A0 (en) 1999-03-12
AU2379297A (en) 1997-08-28
AP9801306A0 (en) 1998-09-30
NO983672L (en) 1998-10-09
CA2245920A1 (en) 1997-08-14
DE19606355A1 (en) 1997-08-14
CZ253298A3 (en) 1999-01-13
KR19990082434A (en) 1999-11-25

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