WO1996018338A1 - Internal registration of gas/air - and other fluid flows in a human body and use of pressure sensors for such registration - Google Patents
Internal registration of gas/air - and other fluid flows in a human body and use of pressure sensors for such registration Download PDFInfo
- Publication number
- WO1996018338A1 WO1996018338A1 PCT/NO1995/000230 NO9500230W WO9618338A1 WO 1996018338 A1 WO1996018338 A1 WO 1996018338A1 NO 9500230 W NO9500230 W NO 9500230W WO 9618338 A1 WO9618338 A1 WO 9618338A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- temperature
- registration
- sensors
- pressure
- fluid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
- A61B5/0878—Measuring breath flow using temperature sensing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B7/00—Instruments for auscultation
- A61B7/003—Detecting lung or respiration noise
Definitions
- the present invention relates to a method for internal registration of the flow of a fluid into, in or out of a living body.
- the invention relates especially to a method for the registration of respiration in human beings, preferably during sleep.
- the invention also relates to the use of pressure-sensitive sensors that are known per se for the registration of temperature in connection with the aforementioned method.
- Sleep is a periodic and, as a rule, rhythmically occurring state in which physical and mental activity are diminished.
- a problem such as snoring is also a real family or social problem because of the disturbance snoring can cause for other people in the period of sleep necessary for each individual .
- respiration is also an important parameter for the diagnosis of a patient's condition.
- pressure registrations of this kind are carried out by means of so-called micro-sensor catheters, ie, fine plastic tubes into which are mounted small pressure sensors.
- Pressure-related signals from both direct and indirect pressure which is exerted on these sensors, are conveyed to the sleep registration equipment and produced as pressure curves, eg, on the screen of a personal computer.
- pressure sensors of this kind are usually more or less temperature-sensitive by nature, it is essential that the effects of temperature be compensated so that temperature fluctuations have a minimal effect on the pressure signals.
- the present invention aims to utilise the effects of temperature in pressure sensors that are known per se.
- Figure 1 illustrates internal pressure/temperature sensors in the flow path of the respiratory fluid
- Ficfure 2 shows the tidal volume signal of respiration with internal temperature registration
- Figure 3 illustrates a Wheatstone bridge used as a pressure and fluid flow sensor.
- the present invention is thus based on the utilisation of this temperature sensitivity in order to register a patient's inhalation and exhalation, ie, respiration, by means of temperature-sensitive sensors which are placed in one or more positions in the airway, such as is shown in Figure 1 where five sensors are arranged in a fine, flexible tube.
- the present invention relates to a method for registering the flow of a fluid inside, in or ou: of a living body, and this method is characterised in that one or a series of pressure-sensitive sensors are provided at ona or more points along the flow path of the fluid and that registration takes place through the utilisation of the sensor's/sensors' inherent, temperature-dependent, physical and electrical properties, when measuring the temperature and difference in temperature in the flowing fluid.
- the invention also relates to the use of pressure-sensitive sensors that are known per se for in vivo measuring of the temperature and difference in temperature in fluids which flow into, in or out of a living body.
- the measurements can be taken in the urinary tract, in blood vessels and so forth, but the invention shall be described in more detail and will also have a special application in connection with the registration of the respiration of an individual, particularly during sleep.
- Figure 2 illustrates the registration of an individual's respiration during sleep and reproduces the tidal volume signal for inspiration and expiration with internal temperature registration.
- the aforementioned temperature-sensitive sensors may, for example, be placed in a fine plastic tube in the same way as pressure sensors are mounted in a micro-tip-sensor catheter, see the illustration in Figure 1.
- the registration of respiration is based on the fact that the temperature of inhaled air is lower than that of exhaled air and that the quantity of air per time unit also has an effect on the behaviour of the temperature. It is thereby possible to obtain registration of the patient's respiration.
- These temperature registrations are made with the aid of temperature-sensitive resistors, so-called thermistors, semi ⁇ conductor elements, thermoelements and so forth.
- the present invention aims to utilise the temperature-dependent physical and electrical material properties which are inherent in pressure sensors. This makes possible the measurement of both pressure and temperature using one and the same sensor, indeed independent of one another in a certain appiroach, by means of suitable coupling and sensor electronics. How this can be done is described in more detail below with reference to Figure 3.
- Recfistrations of other pressures eg, sound pressure as generated by snoring sounds and heart sounds, are included in th €;se pressure and temperature registrations, and, in addition, it is possible to measure the internal body temperature.
- the pressure sensors are commercially available in the form of micro-tip-pressure catheters. These micro-tip-pressure catheters may optionally be temperature-compensated, but are not necessarily compensated. Usually, pressure sensors made of silicon are used with indiffused resistors and these resistors are usually connected in a so-called Wheatstone bridge as a whole or half bridge of a known type per se. A bridge connection of this type is illustrated in Figure 3.
- R denotes pressure sensor resistors
- R comp a temperature-compensating resistor
- R Q a zero point adjustment resistor
- the letter I is used to denote the sensor excitation current .
- the Wheatstone sensor bridge connection works with four active sensor resistors or two active sensor resistors and two passive resistors.
- the effect of temperature is a known physical effect and the temperature coefficient for the resistors used is about 0.2%/°C, without this value being of any crucial importance to the principle.
- This effect has a high degree of stability, which means great advantages with a view to obtaining usable signals and registrations chiefly of respiration, but also registrations of other forms of gas and liquid flows.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Physiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8518636A JPH10510726A (ja) | 1994-12-14 | 1995-12-12 | 人体内のガス/空気および他の流体の流れの内部的記録ならびに記録のための圧力センサの使用 |
AU43179/96A AU4317996A (en) | 1994-12-14 | 1995-12-12 | Internal registration of gas/air - and other fluid flows in a human body and use of pressure sensors for such registration |
EP95941931A EP0797403A1 (en) | 1994-12-14 | 1995-12-12 | Internal registration of gas/air - and other fluid flows in a human body and use of pressure sensors for such registration |
US08/864,787 US6216702B1 (en) | 1994-12-14 | 1997-05-29 | Internal registration of gas/air—and other fluid flows in a human body and use of pressure sensors for such registration |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO944844A NO301210B1 (no) | 1994-12-14 | 1994-12-14 | Anvendelse av sensorer for måling av et individs respirasjonstidevolum |
NO944844 | 1994-12-14 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/864,787 Continuation US6216702B1 (en) | 1994-12-14 | 1997-05-29 | Internal registration of gas/air—and other fluid flows in a human body and use of pressure sensors for such registration |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996018338A1 true WO1996018338A1 (en) | 1996-06-20 |
Family
ID=19897754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/NO1995/000230 WO1996018338A1 (en) | 1994-12-14 | 1995-12-12 | Internal registration of gas/air - and other fluid flows in a human body and use of pressure sensors for such registration |
Country Status (9)
Country | Link |
---|---|
US (1) | US6216702B1 (no) |
EP (1) | EP0797403A1 (no) |
JP (1) | JPH10510726A (no) |
CN (1) | CN1112901C (no) |
AU (1) | AU4317996A (no) |
CA (1) | CA2206118A1 (no) |
NO (1) | NO301210B1 (no) |
RU (1) | RU2194439C2 (no) |
WO (1) | WO1996018338A1 (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6250307B1 (en) * | 1999-09-17 | 2001-06-26 | Pi Medical, Inc. | Snoring treatment |
US6390096B1 (en) * | 1999-09-17 | 2002-05-21 | Pi Medical, Inc. | Needle with pre-loaded implant for snoring treatment |
US6450169B1 (en) * | 1999-09-17 | 2002-09-17 | Pi Medical, Inc. | Braided implant for snoring treatment |
US6431174B1 (en) * | 2000-08-10 | 2002-08-13 | Pi Medical, Inc. | Method and apparatus to treat conditions of the naso-pharyngeal area |
US6636767B1 (en) * | 1999-09-29 | 2003-10-21 | Restore Medical, Inc. | Implanatable stimulation device for snoring treatment |
NO20002538L (no) * | 2000-05-16 | 2001-11-19 | Medisinsk Registrering Og Anal | Deteksjon av pusteforstyrrelser |
US7137952B2 (en) * | 2001-06-29 | 2006-11-21 | Ecole Polytechnique Federale De Lausanne-Service Des Relations Industrielles | Intraocular pressure recording system |
US20030130588A1 (en) * | 2002-01-10 | 2003-07-10 | Igal Kushnir | Method and system for analyzing respiratory tract sounds |
US7017582B2 (en) * | 2002-02-04 | 2006-03-28 | Restore Medical Inc. | Stiffening pharyngeal wall treatment |
US7146981B2 (en) | 2002-02-04 | 2006-12-12 | Restore Medical, Inc. | Pharyngeal wall treatment |
US20060100537A1 (en) * | 2002-04-03 | 2006-05-11 | Williams David R | Spirometer |
US7094208B2 (en) | 2002-04-03 | 2006-08-22 | Illinois Institute Of Technology | Spirometer |
US20050080348A1 (en) * | 2003-09-18 | 2005-04-14 | Stahmann Jeffrey E. | Medical event logbook system and method |
US6949075B2 (en) * | 2002-12-27 | 2005-09-27 | Cardiac Pacemakers, Inc. | Apparatus and method for detecting lung sounds using an implanted device |
US20050154412A1 (en) * | 2003-09-19 | 2005-07-14 | Restore Medical, Inc. | Airway implant and delivery tool |
US20050065615A1 (en) * | 2003-09-19 | 2005-03-24 | Restore Medical, Inc. | Airway implant and delivery tool and kit |
US7237554B2 (en) * | 2003-10-31 | 2007-07-03 | Restore Medical, Inc. | Airway implant |
US7213599B2 (en) * | 2003-10-31 | 2007-05-08 | Restore Medical, Inc. | Airway implant |
EP1691685A4 (en) * | 2003-11-17 | 2008-09-03 | Spirojet Medical Ltd | SPIROMETER |
US7322356B2 (en) * | 2005-02-24 | 2008-01-29 | Restore Medical, Inc. | Combination sleep apnea treatment |
US7630755B2 (en) | 2005-05-04 | 2009-12-08 | Cardiac Pacemakers Inc. | Syncope logbook and method of using same |
JP2010131264A (ja) * | 2008-12-05 | 2010-06-17 | Nippon Koden Corp | 呼吸気情報測定センサ |
US9585601B2 (en) | 2013-08-15 | 2017-03-07 | Chunyuan Qiu | Systems, methods and devices for diagnosing sleep apnea |
WO2015181140A1 (en) | 2014-05-26 | 2015-12-03 | Spiro Medical As | System for monitoring respiratory effort |
CN104857648B (zh) * | 2015-05-20 | 2017-12-01 | 广州软图信息科技有限公司 | 净化空气的呼吸眼镜 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE377276B (no) * | 1970-01-24 | 1975-06-30 | Siemens Ag | |
US4554927A (en) * | 1983-08-30 | 1985-11-26 | Thermometrics Inc. | Pressure and temperature sensor |
Family Cites Families (14)
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US3672352A (en) * | 1969-04-09 | 1972-06-27 | George D Summers | Implantable bio-data monitoring method and apparatus |
US3961626A (en) * | 1975-04-18 | 1976-06-08 | Houchen John R | Hyperbaric and underwater extrathorasic assisted breathing method and apparatus |
JPS5948106B2 (ja) | 1980-08-27 | 1984-11-24 | 株式会社東芝 | 呼吸監視装置 |
US4938212A (en) * | 1987-10-16 | 1990-07-03 | Puritan-Bennett Corporation | Inspiration oxygen saver |
US4986671A (en) | 1989-04-12 | 1991-01-22 | Luxtron Corporation | Three-parameter optical fiber sensor and system |
US5056519A (en) * | 1990-05-14 | 1991-10-15 | Vince Dennis J | Unilateral diaphragmatic pacer |
US5339051A (en) * | 1991-12-09 | 1994-08-16 | Sandia Corporation | Micro-machined resonator oscillator |
US5311875A (en) * | 1992-11-17 | 1994-05-17 | Peter Stasz | Breath sensing apparatus |
US5522397A (en) | 1993-03-10 | 1996-06-04 | Vermaak; Jan C. | Method of and apparatus for monitoring lung function |
DE4439080B4 (de) * | 1994-11-02 | 2004-06-03 | Ganshorn Medizin Electronic Gmbh | Ganzkörper-Plethysmograph |
US5540220A (en) * | 1994-12-08 | 1996-07-30 | Bear Medical Systems, Inc. | Pressure-limited, time-cycled pulmonary ventilation with volume-cycle override |
GB2307641A (en) * | 1995-11-28 | 1997-06-04 | Kenneth Chatham | Apparatus for testing respiratory ability |
US5833603A (en) * | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
US5836989A (en) * | 1996-12-26 | 1998-11-17 | Medtronic, Inc. | Method and apparatus for controlling an implanted medical device in a time-dependent manner |
-
1994
- 1994-12-14 NO NO944844A patent/NO301210B1/no not_active IP Right Cessation
-
1995
- 1995-12-12 CA CA002206118A patent/CA2206118A1/en not_active Abandoned
- 1995-12-12 JP JP8518636A patent/JPH10510726A/ja active Pending
- 1995-12-12 CN CN95196797A patent/CN1112901C/zh not_active Expired - Fee Related
- 1995-12-12 RU RU97111800/14A patent/RU2194439C2/ru not_active IP Right Cessation
- 1995-12-12 WO PCT/NO1995/000230 patent/WO1996018338A1/en not_active Application Discontinuation
- 1995-12-12 AU AU43179/96A patent/AU4317996A/en not_active Abandoned
- 1995-12-12 EP EP95941931A patent/EP0797403A1/en not_active Ceased
-
1997
- 1997-05-29 US US08/864,787 patent/US6216702B1/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE377276B (no) * | 1970-01-24 | 1975-06-30 | Siemens Ag | |
US4554927A (en) * | 1983-08-30 | 1985-11-26 | Thermometrics Inc. | Pressure and temperature sensor |
Also Published As
Publication number | Publication date |
---|---|
AU4317996A (en) | 1996-07-03 |
US6216702B1 (en) | 2001-04-17 |
NO944844D0 (no) | 1994-12-14 |
CA2206118A1 (en) | 1996-06-20 |
NO944844L (no) | 1996-06-17 |
CN1169664A (zh) | 1998-01-07 |
CN1112901C (zh) | 2003-07-02 |
NO301210B1 (no) | 1997-09-29 |
RU2194439C2 (ru) | 2002-12-20 |
EP0797403A1 (en) | 1997-10-01 |
JPH10510726A (ja) | 1998-10-20 |
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