WO1991018992A3 - Procedes de fabrication et d'utilisation de matiere proteique presente dans le kininogene de masse moleculaire elevee exempt de kinine - Google Patents

Procedes de fabrication et d'utilisation de matiere proteique presente dans le kininogene de masse moleculaire elevee exempt de kinine Download PDF

Info

Publication number
WO1991018992A3
WO1991018992A3 PCT/US1991/003956 US9103956W WO9118992A3 WO 1991018992 A3 WO1991018992 A3 WO 1991018992A3 US 9103956 W US9103956 W US 9103956W WO 9118992 A3 WO9118992 A3 WO 9118992A3
Authority
WO
WIPO (PCT)
Prior art keywords
kinin
molecular weight
high molecular
free high
weight kininogen
Prior art date
Application number
PCT/US1991/003956
Other languages
English (en)
Other versions
WO1991018992A2 (fr
Inventor
Deane F Mosher
Shinji Asakura
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of WO1991018992A2 publication Critical patent/WO1991018992A2/fr
Publication of WO1991018992A3 publication Critical patent/WO1991018992A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/12—Polypeptides, proteins or derivatives thereof, e.g. degradation products thereof
    • A61L33/128—Other specific proteins or polypeptides not covered by A61L33/122 - A61L33/126
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/921—Blood vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Procédés d'utilisation d'une matière protéique présente dans un kininogène de masse moléculaire élevée exempt de kinine afin de traiter des surfaces de manière à empêcher ou à réduire au minimum l'adhérence par des composants du sang et/ou des cellules animales. Par exemple, on peut traiter dans des applications médicales des tubes plastiques ou d'autres conduits transportant du sang, afin de réduire la tendance du sang à bloquer le conduit. L'invention concerne également un procédé amélioré de purification de kininogène de masse moléculaire élevée exempt de kinine.
PCT/US1991/003956 1990-06-08 1991-06-05 Procedes de fabrication et d'utilisation de matiere proteique presente dans le kininogene de masse moleculaire elevee exempt de kinine WO1991018992A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US544,133 1990-06-08
US07/544,133 US5114413A (en) 1990-06-08 1990-06-08 Methods to make and use proteinaceous material present in kinin-free high molecular weight kininogen

Publications (2)

Publication Number Publication Date
WO1991018992A2 WO1991018992A2 (fr) 1991-12-12
WO1991018992A3 true WO1991018992A3 (fr) 1992-10-29

Family

ID=24170890

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/003956 WO1991018992A2 (fr) 1990-06-08 1991-06-05 Procedes de fabrication et d'utilisation de matiere proteique presente dans le kininogene de masse moleculaire elevee exempt de kinine

Country Status (3)

Country Link
US (1) US5114413A (fr)
AU (1) AU8214091A (fr)
WO (1) WO1991018992A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3073439B2 (ja) * 1996-02-08 2000-08-07 雪印乳業株式会社 骨形成促進及び骨吸収防止剤
AU2003217636A1 (en) * 2002-02-22 2003-09-09 Flextronics International Usa, Inc. Electronic component design, procurement and manufacturing collaboration
DE202008006190U1 (de) * 2008-05-06 2008-07-17 Sellin, Lothar Restenoseprophylaxe

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4251510A (en) * 1979-08-15 1981-02-17 Cutter Laboratories, Inc. Intravenously injectable solution of plasma protein fraction free from bradykinin, kininogen and prekallikrein activators and processes for its production

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5439983A (en) * 1977-09-05 1979-03-28 Hiroyuki Sumi Antithrombotic material
JPS5447799A (en) * 1977-09-22 1979-04-14 Agency Of Ind Science & Technol Preparation of stereoregular amino acid resin
JPS54135494A (en) * 1978-04-13 1979-10-20 Asahi Chemical Ind Medical material
JPS58118763A (ja) * 1981-12-30 1983-07-14 日東電工株式会社 抗血栓性材料
US5047020A (en) * 1987-09-14 1991-09-10 Baxter International Inc. Ionic heparin coating
US5019393A (en) * 1988-08-03 1991-05-28 New England Deaconess Hospital Corporation Biocompatible substance with thromboresistance
US5053048A (en) * 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US4999210A (en) * 1989-01-18 1991-03-12 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4251510A (en) * 1979-08-15 1981-02-17 Cutter Laboratories, Inc. Intravenously injectable solution of plasma protein fraction free from bradykinin, kininogen and prekallikrein activators and processes for its production

Also Published As

Publication number Publication date
US5114413A (en) 1992-05-19
WO1991018992A2 (fr) 1991-12-12
AU8214091A (en) 1991-12-31

Similar Documents

Publication Publication Date Title
AU2422897A (en) Photopheresis treatment of leukocytes
PL321781A1 (en) Method of coating objects with hialuronic acid, its derivatives and semi-synthetic polymers
AU588545B2 (en) Flexible multilayered polymeric films, useful in the production of medical solution pouches
AU555682B2 (en) Continuous ambulatory peritoneal dialysis clamping system
AU675561B2 (en) Medical material and process for producing the same
MY129973A (en) Sulphonylbenzyl-substituted pyridones.
WO1991008008A3 (fr) Solution de dialyse peritoneale tamponnee a l'histidine
AU4820090A (en) Process and device for continuous manufacture of fibre-reinforced plastic pipes
IT8347563A0 (it) Procedimento per il recupero di sostanze nutrienti per l'agricoltura da acque di scarico contenenti ammoniaca,potassio e fosfati
AU5048090A (en) Human derived monocyte attracting purified protein product useful in a method of treating infection and neoplasm in human body, and the cloning of full length cdna thereof
AU2415888A (en) A method for preventing blood coaguli from being formed in the extra-body circuit of dialysis apparatus and composition useful therefor
NZ263740A (en) Ionene polymers as anthelmintics
PH27214A (en) N-2,3-butadienyl tri and tetraaminoalkane derivatives
MY131053A (en) 2-saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
WO1991018992A3 (fr) Procedes de fabrication et d'utilisation de matiere proteique presente dans le kininogene de masse moleculaire elevee exempt de kinine
CA2216718A1 (fr) Adsorbant de facteurs associes a des pathologies dans des liquides biologiques, procede d'elimination par adsorption, purificateur de liquides biologiques, et appareil de purification de liquides biologiques
LU81242A1 (fr) Composition en vue de reduire le taux de phenylalanine dans le sang,et son procede d'utilisation
AU2456888A (en) Monoclonal antibodies specific for HIV and hybridomas for their production
EP0276007A3 (fr) Nourriture pour animaux à fourrure et procédé de préparation de celle-ci
BG102404A (en) The application of flupirtin for the prevention and treatment of diseases related to impairement of the haematopoeic cellular system
ES2014042A6 (es) Un procedimiento para la preparacion de una composicion de 1-(2'-desoxi -2' fluor -b- d- arabinofuranosil) -5-etiluracilo.
NZ213370A (en) Method of treating viral infections of selected trees and field crops using ribavirin (1-b-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) or the 2,3,5-triacetyl or 5'-butyryl derivative thereof
AU2747488A (en) Method of extrusion of compositions of linear polyethylene and polyacetal, and films thereof
DE59601383D1 (de) Zweibandagige bodenverdichtungsvorrichtung und deren lenkung
AU2064388A (en) Blends and films of linear ethylene polymers with polyamide, and method of their extrusion

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU NL SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU NL SE

NENP Non-entry into the national phase

Ref country code: CA