UY38534A - Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza huma - Google Patents
Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza humaInfo
- Publication number
- UY38534A UY38534A UY0001038534A UY38534A UY38534A UY 38534 A UY38534 A UY 38534A UY 0001038534 A UY0001038534 A UY 0001038534A UY 38534 A UY38534 A UY 38534A UY 38534 A UY38534 A UY 38534A
- Authority
- UY
- Uruguay
- Prior art keywords
- monoclonal antibodies
- parainfluenza virus
- protein
- chimeral
- huma
- Prior art date
Links
- 208000002606 Paramyxoviridae Infections Diseases 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La invención presenta la generación de anticuerpos monoclonales, o fragmentos de los mismos, que reconocen la proteína L quimérica del virus parainfluenza humano (PIV), donde dichos anticuerpos monoclonales o fragmentos de estos comprenden una región variable de la cadena pesada y una región variable de la cadena liviana. Se proporciona además, un método de diagnóstico de infección por PIV en una muestra biológica de secreción nasofaríngea, que utiliza los anticuerpos monoclonales en formato de kit de diagnóstico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2018003869A CL2018003869A1 (es) | 2018-12-28 | 2018-12-28 | Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza humana (piv), secuencias nucleotídicas; método y kit de diagnóstico de infección producida por piv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY38534A true UY38534A (es) | 2020-07-31 |
Family
ID=71125643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001038534A UY38534A (es) | 2018-12-28 | 2019-12-27 | Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza huma |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220089697A1 (es) |
| EP (1) | EP3904379A4 (es) |
| KR (1) | KR20210110660A (es) |
| CN (1) | CN113490685A (es) |
| AR (1) | AR117548A1 (es) |
| BR (1) | BR112021012788A2 (es) |
| CA (1) | CA3125208A1 (es) |
| CL (1) | CL2018003869A1 (es) |
| CO (1) | CO2021008770A2 (es) |
| MX (1) | MX2021007870A (es) |
| PE (1) | PE20212104A1 (es) |
| UY (1) | UY38534A (es) |
| WO (1) | WO2020132774A1 (es) |
| ZA (1) | ZA202104990B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113736920B (zh) * | 2021-09-15 | 2023-09-01 | 丹娜(天津)生物科技股份有限公司 | 一种九项呼吸道病原体分子检测试剂盒及其使用方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6015664A (en) | 1995-11-03 | 2000-01-18 | Mcw Research Foundation | Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B |
| US20100233674A1 (en) * | 2002-04-25 | 2010-09-16 | University Hospitals Of Cleveland | Cells for detection and production of influenza and parainfluenza viruses |
| TW200501985A (en) * | 2002-07-25 | 2005-01-16 | Medimmune Inc | Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies |
| US8492097B2 (en) * | 2006-04-24 | 2013-07-23 | Diagnostic Hybrids, Inc. | Compositions and methods for human metapneumovirus monoclonal antibodies |
| US8003314B2 (en) * | 2007-04-16 | 2011-08-23 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
| WO2011020079A1 (en) * | 2009-08-13 | 2011-02-17 | Calmune Corporation | Antibodies against human respiratory syncytial virus (rsv) and methods of use |
| CA3062786C (en) * | 2010-07-09 | 2022-04-19 | Janssen Vaccines & Prevention B.V. | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| CN102140550A (zh) | 2011-03-25 | 2011-08-03 | 武汉大学 | 副流感病毒一步rt-pcr检测试剂盒 |
| CA3128591A1 (en) * | 2012-01-24 | 2013-08-01 | University Of Georgia Research Foundation, Inc. | Parainfluenza virus 5 based vaccines |
| CL2015002152A1 (es) * | 2015-07-31 | 2016-06-03 | Pontificia Universidad Católica De Chile | Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh |
| CN105441589B (zh) | 2015-12-21 | 2018-12-21 | 深圳生科原生物股份有限公司 | 人副流感病毒ⅰ、ⅱ、ⅲ、ⅳ型四重pcr检测试剂盒及其检测方法 |
| CL2016000164A1 (es) * | 2016-01-21 | 2016-07-29 | Pontificia Universidad Católica De Chile | Anticuerpos monoclonales específicos para el antígeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por adv. |
-
2018
- 2018-12-28 CL CL2018003869A patent/CL2018003869A1/es unknown
-
2019
- 2019-12-27 MX MX2021007870A patent/MX2021007870A/es unknown
- 2019-12-27 AR ARP190103908A patent/AR117548A1/es unknown
- 2019-12-27 KR KR1020217024084A patent/KR20210110660A/ko active Search and Examination
- 2019-12-27 CN CN201980093165.9A patent/CN113490685A/zh active Pending
- 2019-12-27 CA CA3125208A patent/CA3125208A1/en active Pending
- 2019-12-27 EP EP19903462.0A patent/EP3904379A4/en active Pending
- 2019-12-27 WO PCT/CL2019/050157 patent/WO2020132774A1/es unknown
- 2019-12-27 BR BR112021012788A patent/BR112021012788A2/pt unknown
- 2019-12-27 PE PE2021001089A patent/PE20212104A1/es unknown
- 2019-12-27 US US17/418,617 patent/US20220089697A1/en active Pending
- 2019-12-27 UY UY0001038534A patent/UY38534A/es unknown
-
2021
- 2021-07-01 CO CONC2021/0008770A patent/CO2021008770A2/es unknown
- 2021-07-15 ZA ZA2021/04990A patent/ZA202104990B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR117548A1 (es) | 2021-08-11 |
| CN113490685A (zh) | 2021-10-08 |
| CO2021008770A2 (es) | 2021-07-19 |
| CL2018003869A1 (es) | 2021-01-15 |
| EP3904379A1 (en) | 2021-11-03 |
| CA3125208A1 (en) | 2020-07-02 |
| WO2020132774A1 (es) | 2020-07-02 |
| US20220089697A1 (en) | 2022-03-24 |
| BR112021012788A2 (pt) | 2021-11-16 |
| KR20210110660A (ko) | 2021-09-08 |
| EP3904379A4 (en) | 2022-08-17 |
| PE20212104A1 (es) | 2021-11-04 |
| MX2021007870A (es) | 2021-12-10 |
| ZA202104990B (en) | 2023-01-25 |
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