UY26534A1 - Dispositivo osmótico que contiene alprazolam y un agente antipsicótico - Google Patents
Dispositivo osmótico que contiene alprazolam y un agente antipsicóticoInfo
- Publication number
- UY26534A1 UY26534A1 UY26534A UY26534A UY26534A1 UY 26534 A1 UY26534 A1 UY 26534A1 UY 26534 A UY26534 A UY 26534A UY 26534 A UY26534 A UY 26534A UY 26534 A1 UY26534 A1 UY 26534A1
- Authority
- UY
- Uruguay
- Prior art keywords
- outer shell
- osmotic
- antipsychotic agent
- device containing
- osmotic device
- Prior art date
Links
- 230000003204 osmotic effect Effects 0.000 title abstract 4
- 239000000164 antipsychotic agent Substances 0.000 title abstract 3
- VREFGVBLTWBCJP-UHFFFAOYSA-N alprazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1 VREFGVBLTWBCJP-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004538 alprazolam Drugs 0.000 title abstract 2
- 230000006835 compression Effects 0.000 abstract 2
- 238000007906 compression Methods 0.000 abstract 2
- 239000007921 spray Substances 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención provee un dispositivo osmótico que contiene alprazolam de liberación controlada en el núcleo, opcionalmente en combinación con un agente antipsicótico en una cubierta externa de liberación rápida. Un amplio rango de agentes antipsicóticos pueden ser utilizados en este dispositivo. Realizaciones particulares de la invención proveen dispositivos osmótico con perfiles de liberación predeterminados. Una realización del dispositivo osmóticos incluye una cubierta externa que ha sido aplicada por pulverización en lugar de ser aplicada por compresión sobre el dispositivo. El dispositivo con la cubierta externa aplicada por pulverización es más pequeno y fácil de tragar que un dispositivo similar con una cubierta externa aplicada por compresión. El dispositivo es útil para el tratamiento de los desórdenes relacionados con la depresión, la ansiedad o la psicosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17582700P | 2000-01-13 | 2000-01-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26534A1 true UY26534A1 (es) | 2001-09-28 |
Family
ID=22641798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26534A UY26534A1 (es) | 2000-01-13 | 2001-01-12 | Dispositivo osmótico que contiene alprazolam y un agente antipsicótico |
Country Status (6)
Country | Link |
---|---|
US (1) | US6599532B2 (es) |
AR (1) | AR026832A1 (es) |
AU (1) | AU2001227758A1 (es) |
CA (1) | CA2396214A1 (es) |
UY (1) | UY26534A1 (es) |
WO (1) | WO2001051040A1 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040213848A1 (en) * | 2001-09-28 | 2004-10-28 | Shun-Por Li | Modified release dosage forms |
US20040146559A1 (en) * | 2002-09-28 | 2004-07-29 | Sowden Harry S. | Dosage forms having an inner core and outer shell with different shapes |
US20040253312A1 (en) * | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
PT1539115E (pt) * | 2002-07-29 | 2008-01-14 | Alza Corp | Métodos e formas de dosagem para libertação controlada de paliperidona |
US20050232995A1 (en) * | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
US20050208132A1 (en) * | 2002-07-29 | 2005-09-22 | Gayatri Sathyan | Methods and dosage forms for reducing side effects of benzisozazole derivatives |
MXPA05000294A (es) | 2002-07-30 | 2005-08-19 | Peter Migaly | Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas. |
AU2003225945B2 (en) * | 2002-09-28 | 2009-04-23 | Mcneil-Ppc, Inc. | Immediate release dosage form comprising shell having openings therein |
US7807197B2 (en) * | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
EP2255795A1 (en) * | 2002-09-28 | 2010-12-01 | McNeil-PPC, Inc. | Immediate release dosage form comprising shell having openings therein |
AU2003284899A1 (en) * | 2002-10-29 | 2004-05-25 | Miicro, Inc. | Novel combination therapy for schizophrenia focused on improved cognition: 5-ht-2a/d2 blockade with adjunctive blockade of prefrontal da reuptake |
AR042806A1 (es) * | 2002-12-27 | 2005-07-06 | Otsuka Pharma Co Ltd | Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo |
ATE376419T1 (de) | 2002-12-27 | 2007-11-15 | Otsuka Pharma Co Ltd | Carbostyril-derivate mit selektiven serotonin- aufnahme inhibitoren, zur behandlung von gemütskrankheiten |
JP2006528676A (ja) * | 2003-05-16 | 2006-12-21 | ファイザー・プロダクツ・インク | 非定形型抗精神病薬と、gaba調節薬及び/又は抗痙攣薬の治療上の組合せ |
NZ527142A (en) * | 2003-07-23 | 2006-03-31 | Douglas Pharmaceuticals Ltd | A stable suspension formulation |
AU2004264316A1 (en) * | 2003-08-06 | 2005-02-24 | Alza Corporation | Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation |
US7611728B2 (en) * | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
US20050260268A1 (en) * | 2003-09-26 | 2005-11-24 | Modi Nishit B | Methods and dosage forms for controlled delivery of alprazolam |
US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US20050171088A1 (en) * | 2004-01-30 | 2005-08-04 | Astrazeneca Ab | Treatment of psychoses with dibenzothiazepine antipsychotic |
US8252331B2 (en) * | 2004-12-03 | 2012-08-28 | Osmotica Kereskedelmi és Szolgáltató, KFT | Osmotic device containing amantadine and an osmotic salt |
US8574626B2 (en) | 2004-12-03 | 2013-11-05 | Osmotica Kereskedelmi és Szolgáltató KFT | Osmotic device containing amantadine and an osmotic salt |
AR053986A1 (es) | 2004-12-03 | 2007-05-30 | Osmotica Pharmaceutical Argent | Dispositivo osmotico que contiene amantadina y una sal osmotica |
WO2006085168A2 (en) * | 2005-01-07 | 2006-08-17 | Ranbaxy Laboratories Limited | Solid oral dosage forms of ziprasidone containing colloidal silicone dioxide |
EP1690540A1 (en) * | 2005-02-15 | 2006-08-16 | Neuro3D | Composition comprising ocaperidone |
US8673352B2 (en) * | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
US20070212412A1 (en) * | 2005-09-08 | 2007-09-13 | H. Lundbeck A/S | Stable solid formulation of sertindole |
US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
WO2007073702A2 (es) | 2005-12-29 | 2007-07-05 | Osmotica Corp. | Comprimido multicapa con combinación de triple liberación |
US20070166381A1 (en) * | 2006-01-06 | 2007-07-19 | Iran Reyes | Osmotic dosage form with controlled release and fast release aspects |
US10213393B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság | Composition and method for treating neurological disease |
US20190247331A1 (en) | 2018-02-15 | 2019-08-15 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
US10213394B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4968507A (en) * | 1984-06-20 | 1990-11-06 | Merck & Co., Inc. | Controlled porosity osmotic pump |
US5225198A (en) * | 1991-08-27 | 1993-07-06 | Cygnus Therapeutic Systems | Transdermal administration of short or intermediate half-life benzodiazepines |
ATE188375T1 (de) * | 1992-11-17 | 2000-01-15 | Yoshitomi Pharmaceutical | Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung |
TW235239B (es) * | 1992-11-20 | 1994-12-01 | Pfizer | |
AU7706598A (en) * | 1997-05-30 | 1998-12-30 | Laboratorios Phoenix U.S.A., Inc. | Multi-layered osmotic device |
-
2001
- 2001-01-08 US US09/756,497 patent/US6599532B2/en not_active Expired - Fee Related
- 2001-01-09 CA CA002396214A patent/CA2396214A1/en not_active Abandoned
- 2001-01-09 AU AU2001227758A patent/AU2001227758A1/en not_active Abandoned
- 2001-01-09 WO PCT/US2001/000637 patent/WO2001051040A1/en active Application Filing
- 2001-01-11 AR ARP010100117A patent/AR026832A1/es unknown
- 2001-01-12 UY UY26534A patent/UY26534A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20020051807A1 (en) | 2002-05-02 |
CA2396214A1 (en) | 2001-07-19 |
AU2001227758A1 (en) | 2001-07-24 |
WO2001051040B1 (en) | 2002-03-07 |
AR026832A1 (es) | 2003-02-26 |
WO2001051040A1 (en) | 2001-07-19 |
US6599532B2 (en) | 2003-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ABAN | Application deemed to be withdrawn (no publication fee paid) |
Effective date: 20090814 |