US2218899A - Pipette filler - Google Patents
Pipette filler Download PDFInfo
- Publication number
- US2218899A US2218899A US299483A US29948339A US2218899A US 2218899 A US2218899 A US 2218899A US 299483 A US299483 A US 299483A US 29948339 A US29948339 A US 29948339A US 2218899 A US2218899 A US 2218899A
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- Prior art keywords
- piston
- pipette
- port
- piston rod
- valve
- Prior art date
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
Definitions
- This invention relates to pipetting in which liquids are drawn into a "small glass colunm or pipette, usually by the application of suction to one end of the pipette by the mouth of the operator. It frequently happens that the liquid to be drawn into the glass column or pipette is noxious, or unpleasant to taste; and in such cases it is desired to eliminate the necessity of application of the mouth of the operator.
- There are many devices well known to the prior art which are calculated to accomplish this, but all of those of which I am aware have objectionable features. Some of them employ collapsible rubber bulbs which rapidly deteriorate. Other devices embody complex instrumentalities and are not only expensive to manufacture but are difiicult to operate. 7
- Another object is the provision of a device of the class described which is rugged and durable in service.
- Figure 1 is an elevation of the device of the invention as it is applied to a pipette of conventional design
- FIG. 1 is an enlarged fragmentary view partly in section;
- Figure 3 is a .view similar to Figure 2 but disclosing the instrumentalities thereof in another stage of operation;
- Figure 4 is a sectional view on the line IV-IV' of Figure 3.
- the numeral I designates'a cylindrical metallic barrel having a smooth interior bore 2.
- One end of the cylindrical barrel I is provided with a plug 3 having a bore or port 5 extendingtherethrough.
- the outer end of the port 5 is such as to readily accommodate and establish proper communication with a pipette, designated hereinafter at 6; and for this purpose it is desirable that the material of the plug 3, or at least that portion thereof which comprises the wall of the bore or port 5, is constructed of a resilient material, such as rubber.
- a freely reciprocable piston 9 Disposed within the smooth interior bore'2 of the cylindrical metallic barrel I is a freely reciprocable piston 9, the head of which faces the plug 3 and is provided with a central aperture or port II.
- a piston rod I2 which extends entirely therethrough and through the central aperture or port II and is adapted for relative
- the piston 9 is adaptedto be recipmovement with respect thereto.
- a pair of cross bars I3 is carried by the piston rod I2 for limiting the movement in one direction of the piston rod I2 through the central aperture or port II in the head of the piston 9.
- valve I7 is shown as comprising an element having a substantially flat head l8 on its outer end, and provided on its inner end with a substantially flat annular seat I9 which is adapted to close the aperture 0! port I I in the piston 9.
- valve seat I9 when th piston rod I2 is moved downwardly into the smooth interior bore 2 of the cylindrical barrel I, the valve seat I9 will move away from the piston 9 and when this movement is reversed, the valve seat I9 will seal the aperture or port II in the piston 9 and'thereby enable the said piston to provide suction within the interior of the cylindrical barrel I.
- valve II comprises a spherical portion 29 which is connected to the tit I5 on the piston rod I2, and is of such size as will enable its free movement through the I aperture or port II in the piston 9.
- a ferrule designated at 2 I.
- provides a bead 22 which serves as a seat for the flat head I8 on the valve I1.
- the piston 9 When the piston rod I2 is moved upwardly in the cylindrical barrel I, the piston 9-will also be moved upwardly, and the annular seat I9 on the valve I'I will close the port II in the piston 9, thereby providing for suction.
- the piston rod I2 When sufficient liquid has been drawn into the pipette 6, the piston rod I2 is moved even further out of the cylindrical barrel l, whereby the meniscus of the liquid will overrun the desired mark on the pipette.
- the piston rod [2 is moved very rapidly downwardly into the cylindrical barrel I, whereby the said piston rod carrying the valve H will overtravel the piston 9. This movement is continued until the fiat head l8 on the valve l1 seats against the bead 22 on the upper end of the ferrule 2
- the levelof the liquid within the pipette may be adjusted with a fine degree of exactness.
- the end of the barrel opposite that which is provided withthe plug 3 carries in screw threaded engagement a vented cap 24 having a central aperture through which the piston rod l2 extends.
- the outer'of the piston rod 12 is provided with a ring 25 for occupancy by the index or other finger of the operator.
- the device of the invention can be efficiently operated in a minimum of time; and is very rugged in service, as it embodies no instrumentalities which are either fragile or susceptible of material depreciation.
- a pipette filler comprising a cylinder having an opening adapted for communication with one end of a pipette, a. piston in said cylinder, said piston having a port, a piston rod extending through the port in said piston, and means carried on the extremity of said piston rod for open-' ing and closing the opening in said cylinder and the port in said piston, said means being movable with respect to said piston.
- a pipette filler comprising a cylinder having an opening adapted for communication with one end of a pipette, a piston in said cylinder, said piston having a port, a piston rod extending through the port in said piston, means carried on the extremity of said piston rodfor opening and. closing the opening in said cylinder and the port in said piston, said means being. movable with respect to said piston, and means for limiting said movement... f
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- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Description
Oct. 22. 1940. w. WARREN 2,218,899
'PIPBTTE FILLER Filed o 14, 1939 Na 1 5 Y F10. 2., Flam 5.
w JV; +IV
1a 4 i I 19 Z 15::
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Patented Oct. 22,1940
UNITED S-TAIT'VES PATENT -;FF-lCE I William B. Warren, Mount Lebanon, Pa., assignor to Fisher Scientific Company, Pittsburgh, Pa.
- Application October 14, 1939, Serial No. 299,483 v 2 Claims. (01. 221-148) This invention relates to pipetting in which liquids are drawn into a "small glass colunm or pipette, usually by the application of suction to one end of the pipette by the mouth of the operator. It frequently happens that the liquid to be drawn into the glass column or pipette is noxious, or unpleasant to taste; and in such cases it is desired to eliminate the necessity of application of the mouth of the operator. There are many devices well known to the prior art which are calculated to accomplish this, but all of those of which I am aware have objectionable features. Some of them employ collapsible rubber bulbs which rapidly deteriorate. Other devices embody complex instrumentalities and are not only expensive to manufacture but are difiicult to operate. 7
It is among the objects of the present invention to provide an inexpensive and simply operated pipette filler which enables the successful pipetting ofliquids without the application of one end of the pipette to the mouth of the operator.
Another object is the provision of a device of the class described which is rugged and durable in service.
The invention, then, comprises the features hereinafter fully described and as particularly pointed out in the claims, the following description and the annexed drawing setting forth in detail a certain illustrative embodiment of the invention, this being indicative of but one of a number of ways in which the principles of the invention may be employed.
In said drawing:
Figure 1 is an elevation of the device of the invention as it is applied to a pipette of conventional design;
Figure 2 is an enlarged fragmentary view partly in section; v
Figure 3 is a .view similar to Figure 2 but disclosing the instrumentalities thereof in another stage of operation; and
Figure 4 is a sectional view on the line IV-IV' of Figure 3.
Referring more particularly tothe drawing, the numeral I designates'a cylindrical metallic barrel having a smooth interior bore 2. One end of the cylindrical barrel I is provided with a plug 3 having a bore or port 5 extendingtherethrough. The outer end of the port 5 is such as to readily accommodate and establish proper communication with a pipette, designated hereinafter at 6; and for this purpose it is desirable that the material of the plug 3, or at least that portion thereof which comprises the wall of the bore or port 5, is constructed of a resilient material, such as rubber. When-so constructed, the free end 'I of the pipette 6 is firmly gripped and a seal established.
Disposed within the smooth interior bore'2 of the cylindrical metallic barrel I is a freely reciprocable piston 9, the head of which faces the plug 3 and is provided with a central aperture or port II. rocated in the smooth interior bore 2 of the cylindrical barrel I by a piston rod I2, which extends entirely therethrough and through the central aperture or port II and is adapted for relative The piston 9 is adaptedto be recipmovement with respect thereto. A pair of cross bars I3 is carried by the piston rod I2 for limiting the movement in one direction of the piston rod I2 through the central aperture or port II in the head of the piston 9.
The inner end of the piston rod I2 which extends through the piston 9, and which is therefore most adjacent the plug 3, is provided with a tit I5 to which there is connected a resilient valve I? which seals the aperture or port I I in the piston 9. In the present instance, the valve I7 is shown as comprising an element having a substantially flat head l8 on its outer end, and provided on its inner end with a substantially flat annular seat I9 which is adapted to close the aperture 0! port I I in the piston 9.
From the foregoing it will be seen that when th piston rod I2 is moved downwardly into the smooth interior bore 2 of the cylindrical barrel I, the valve seat I9 will move away from the piston 9 and when this movement is reversed, the valve seat I9 will seal the aperture or port II in the piston 9 and'thereby enable the said piston to provide suction within the interior of the cylindrical barrel I.
The remainder of the valve II comprises a spherical portion 29 which is connected to the tit I5 on the piston rod I2, and is of such size as will enable its free movement through the I aperture or port II in the piston 9.
Referring more particularly to Figures 2 and 3 of the drawing, it will be noted that within the inner end of the bore 5 in the plug 3 there is provided a ferrule, designated at 2 I. This ferrule 2|, provides a bead 22 which serves as a seat for the flat head I8 on the valve I1. When the piston rod I2 is moved upwardly in the cylindrical barrel I, the piston 9-will also be moved upwardly, and the annular seat I9 on the valve I'I will close the port II in the piston 9, thereby providing for suction. When sufficient liquid has been drawn into the pipette 6, the piston rod I2 is moved even further out of the cylindrical barrel l, whereby the meniscus of the liquid will overrun the desired mark on the pipette. Immediately the level of liquid has overtravel-ed the desired mark, the piston rod [2 is moved very rapidly downwardly into the cylindrical barrel I, whereby the said piston rod carrying the valve H will overtravel the piston 9. This movement is continued until the fiat head l8 on the valve l1 seats against the bead 22 on the upper end of the ferrule 2|, at which time the liquid is maintained at exactly the proper level. By a very minute movement of the piston rod 12, the levelof the liquid within the pipette may be adjusted with a fine degree of exactness. In order to secure the proper movement of-the piston rod 12 within the cylindrical barrel" I, the end of the barrel opposite that which is provided withthe plug 3 carries in screw threaded engagement a vented cap 24 having a central aperture through which the piston rod l2 extends. In addition, the outer'of the piston rod 12 is provided with a ring 25 for occupancy by the index or other finger of the operator.
Due to its simplicity of construction and manner of operation, the device of the invention can be efficiently operated in a minimum of time; and is very rugged in service, as it embodies no instrumentalities which are either fragile or susceptible of material depreciation.
While I have shown and described one specific embodiment of the present invention, it will be seen that I do not wish to be limited exactly thereto, since various modifications may be made without departing from the scope of the invention, as defined by the following claims.
I claim:
1. A pipette filler comprising a cylinder having an opening adapted for communication with one end of a pipette, a. piston in said cylinder, said piston having a port, a piston rod extending through the port in said piston, and means carried on the extremity of said piston rod for open-' ing and closing the opening in said cylinder and the port in said piston, said means being movable with respect to said piston.
2. A pipette filler comprising a cylinder having an opening adapted for communication with one end of a pipette, a piston in said cylinder, said piston having a port, a piston rod extending through the port in said piston, means carried on the extremity of said piston rodfor opening and. closing the opening in said cylinder and the port in said piston, said means being. movable with respect to said piston, and means for limiting said movement... f
M B. WARREN
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US299483A US2218899A (en) | 1939-10-14 | 1939-10-14 | Pipette filler |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US299483A US2218899A (en) | 1939-10-14 | 1939-10-14 | Pipette filler |
Publications (1)
Publication Number | Publication Date |
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US2218899A true US2218899A (en) | 1940-10-22 |
Family
ID=23155005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US299483A Expired - Lifetime US2218899A (en) | 1939-10-14 | 1939-10-14 | Pipette filler |
Country Status (1)
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US (1) | US2218899A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2564697A (en) * | 1949-08-30 | 1951-08-21 | Armstrong Cork Co | Device for sampling fluid materials |
US2706398A (en) * | 1949-05-26 | 1955-04-19 | Cons Eng Corp | Leak detection |
US2952386A (en) * | 1957-10-07 | 1960-09-13 | Jr Edwin M Knights | Ultramicro buret |
US3236268A (en) * | 1963-04-26 | 1966-02-22 | Gas Getter Co Inc | Device for transferring liquid |
US3595090A (en) * | 1969-09-17 | 1971-07-27 | Drummond Instr Co | Apparatus for drawing fluid into, and discharging fluid from, a pipette |
US4057050A (en) * | 1974-11-29 | 1977-11-08 | Sarstedt W | Devices for extracting blood |
US5257527A (en) * | 1991-06-28 | 1993-11-02 | Kingsbury Alan P | Method and apparatus for measuring components of an ambient fluid |
USD993442S1 (en) * | 2021-05-07 | 2023-07-25 | Reflex Medical Corp. | Pipette |
-
1939
- 1939-10-14 US US299483A patent/US2218899A/en not_active Expired - Lifetime
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2706398A (en) * | 1949-05-26 | 1955-04-19 | Cons Eng Corp | Leak detection |
US2564697A (en) * | 1949-08-30 | 1951-08-21 | Armstrong Cork Co | Device for sampling fluid materials |
US2952386A (en) * | 1957-10-07 | 1960-09-13 | Jr Edwin M Knights | Ultramicro buret |
US3236268A (en) * | 1963-04-26 | 1966-02-22 | Gas Getter Co Inc | Device for transferring liquid |
US3595090A (en) * | 1969-09-17 | 1971-07-27 | Drummond Instr Co | Apparatus for drawing fluid into, and discharging fluid from, a pipette |
US4057050A (en) * | 1974-11-29 | 1977-11-08 | Sarstedt W | Devices for extracting blood |
US5257527A (en) * | 1991-06-28 | 1993-11-02 | Kingsbury Alan P | Method and apparatus for measuring components of an ambient fluid |
USD993442S1 (en) * | 2021-05-07 | 2023-07-25 | Reflex Medical Corp. | Pipette |
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