UA92641C2 - Комбинированная препаративная форма, которая содержит амлодипин и лозартан - Google Patents
Комбинированная препаративная форма, которая содержит амлодипин и лозартанInfo
- Publication number
- UA92641C2 UA92641C2 UAA200814649A UAA200814649A UA92641C2 UA 92641 C2 UA92641 C2 UA 92641C2 UA A200814649 A UAA200814649 A UA A200814649A UA A200814649 A UAA200814649 A UA A200814649A UA 92641 C2 UA92641 C2 UA 92641C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceutical composition
- losartan
- amlodipine
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение касается комбинированной препаративной формы для предотвращения или лечения сердечно-сосудистых расстройств, которая содержит физически отделенные друг от друга амлодипин или его фармацевтически приемлемую соль и лозартан или его фармацевтически приемлемую соль.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020060124552A KR101247583B1 (ko) | 2006-12-08 | 2006-12-08 | 암로디핀 또는 이의 약제학적 허용가능한 염, 및 로자탄또는 이의 약제학적 허용가능한 염을 함유하는 약제학적조성물 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA92641C2 true UA92641C2 (ru) | 2010-11-25 |
Family
ID=39492408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200814649A UA92641C2 (ru) | 2006-12-08 | 2007-12-07 | Комбинированная препаративная форма, которая содержит амлодипин и лозартан |
Country Status (20)
Country | Link |
---|---|
US (1) | US20100233261A1 (ru) |
EP (1) | EP2037917B1 (ru) |
JP (1) | JP4995912B2 (ru) |
KR (1) | KR101247583B1 (ru) |
CN (1) | CN101472587B (ru) |
AU (1) | AU2007328630B2 (ru) |
BR (1) | BRPI0713306A8 (ru) |
CA (1) | CA2654054C (ru) |
EC (1) | ECSP088980A (ru) |
ES (1) | ES2522567T3 (ru) |
HK (1) | HK1131916A1 (ru) |
IL (1) | IL195581A (ru) |
MX (1) | MX2008016099A (ru) |
MY (1) | MY144857A (ru) |
NO (1) | NO20085302L (ru) |
NZ (1) | NZ573223A (ru) |
RU (1) | RU2401107C2 (ru) |
UA (1) | UA92641C2 (ru) |
WO (1) | WO2008069612A1 (ru) |
ZA (2) | ZA200910116B (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI503119B (zh) * | 2009-01-23 | 2015-10-11 | Hanmi Science Co Ltd | 含有氨氯地平(amlodipine)及洛沙坦(losartan)之固體藥學組成物及其製造方法 |
US9161933B2 (en) * | 2009-01-23 | 2015-10-20 | Hanmi Science Co., Ltd | Solid pharmaceutical composition comprising amlodipine and losartan and process for producing same |
CN101849942B (zh) * | 2009-04-02 | 2012-05-23 | 鲁南制药集团股份有限公司 | 治疗高血压的药物组合物 |
CN101849941B (zh) * | 2009-04-02 | 2012-04-18 | 鲁南制药集团股份有限公司 | 一种治疗高血压的药物组合物 |
DK2448561T3 (da) * | 2009-06-30 | 2013-11-25 | Sanofi Sa | Faste farmaceutiske fast dosis-sammensætninger omfattende irbesartan og amlodipin, deres fremstilling og deres terapeutiske anvendelse |
JP2011136908A (ja) * | 2009-12-25 | 2011-07-14 | Kyowa Yakuhin Kogyo Kk | アンギオテンシンii受容体拮抗剤を含む固形製剤および固形製剤におけるアンギオテンシンii受容体拮抗剤の保存安定性向上方法 |
WO2012055941A1 (en) * | 2010-10-27 | 2012-05-03 | Krka,Tovarna Zdravil, D. D., Novo Mesto | Multilayer pharmaceutical composition comprising telmisartan and amlodipine |
CN102335172B (zh) * | 2011-07-20 | 2012-12-12 | 海南锦瑞制药股份有限公司 | 一种氨氯地平与氯沙坦钾药用组合物及其制备方法 |
KR101907881B1 (ko) * | 2011-12-30 | 2018-12-11 | 한미약품 주식회사 | 로자탄, 암로디핀 및 히드로클로로티아자이드를 포함하는 고정 용량 조합 제형 |
KR101392364B1 (ko) * | 2012-04-17 | 2014-05-07 | 한국유나이티드제약 주식회사 | 안정성이 향상된 암로디핀 및 로잘탄을 함유하는 복합제 조성물 |
KR101910901B1 (ko) * | 2013-11-29 | 2018-10-24 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 약제학적 복합 제제 |
KR20150078215A (ko) * | 2013-12-30 | 2015-07-08 | (주) 드림파마 | 에프로사탄 및 암로디핀을 포함하는 복합제제 및 이의 제조방법 |
KR102369607B1 (ko) * | 2014-09-30 | 2022-03-03 | 한미약품 주식회사 | 암로디핀 및 로잘탄을 포함하는 고형 약제학적 조성물 |
KR101914930B1 (ko) * | 2015-03-31 | 2018-11-05 | 한미약품 주식회사 | 암로디핀, 로자탄 및 클로르탈리돈을 포함하는 약제학적 복합 제제 |
KR101750689B1 (ko) * | 2015-09-15 | 2017-06-26 | 주식회사 종근당 | 약제학적 복합제제 |
KR101710441B1 (ko) * | 2015-12-28 | 2017-02-28 | 신풍제약주식회사 | 안정성 및 용출성이 향상된 정제 |
CN110215455A (zh) * | 2019-03-26 | 2019-09-10 | 山东省药学科学院 | 一种用于降血压的药物配方 |
CN112274490B (zh) * | 2020-11-19 | 2022-11-22 | 四川尚锐生物医药有限公司 | 一种氨氯地平氯沙坦钾复方组合物的制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU724576B2 (en) * | 1996-06-24 | 2000-09-28 | Merck & Co., Inc. | A composition of enalapril and losartan |
WO2000027397A1 (en) * | 1998-11-06 | 2000-05-18 | Glaxo Group Limited | Antihypertensive medicaments containing lacidipine and telmisartan |
AU2001284413A1 (en) * | 2000-08-30 | 2002-03-13 | Sankyo Company Limited | Medicinal compositions for preventing or treating heart failure |
US20040137062A1 (en) * | 2001-05-25 | 2004-07-15 | Sham Chopra | Chronotherapy tablet and methods related thereto |
KR100558505B1 (ko) * | 2003-01-27 | 2006-03-07 | 한미약품 주식회사 | 안정한 무정형 암로디핀 캠실레이트, 이의 제조방법 및이를 포함하는 경구투여용 조성물 |
EP1604664A4 (en) * | 2003-01-31 | 2006-12-27 | Sankyo Co | MEDICAMENT FOR THE PREVENTION AND TREATMENT OF ARTERIOSCLEROSIS AND BLOOD HIGH PRESSURE |
AR043395A1 (es) * | 2003-02-28 | 2005-07-27 | Recordati Ireland Ltd | Terapia de combinacion para la hipertension utilizando lercanidipina y un bloqueante de los receptores de angiotensina ii |
US20040253305A1 (en) * | 2003-06-12 | 2004-12-16 | Luner Paul E. | Pharmaceutical compositions of atorvastatin |
US20050187262A1 (en) * | 2004-01-12 | 2005-08-25 | Grogan Donna R. | Compositions comprising (S)-amlodipine and an angiotensin receptor blocker and methods of their use |
US20060068010A1 (en) * | 2004-09-30 | 2006-03-30 | Stephen Turner | Method for improving the bioavailability of orally delivered therapeutics |
ES2452019T5 (es) * | 2004-11-05 | 2021-06-28 | Boehringer Ingelheim Int | Comprimido bicapa que comprende telmisartán y amlodipino |
WO2007001067A2 (en) * | 2005-06-27 | 2007-01-04 | Daiichi Sankyo Company, Limited | Solid dosage form comprising an angiotensin ii receptor antagonist and a calcium channel blocker |
KR100888131B1 (ko) * | 2006-10-10 | 2009-03-11 | 한올제약주식회사 | 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제 |
-
2006
- 2006-12-08 KR KR1020060124552A patent/KR101247583B1/ko active IP Right Grant
-
2007
- 2007-12-07 MY MYPI20084882A patent/MY144857A/en unknown
- 2007-12-07 BR BRPI0713306A patent/BRPI0713306A8/pt active Search and Examination
- 2007-12-07 NZ NZ573223A patent/NZ573223A/en not_active IP Right Cessation
- 2007-12-07 AU AU2007328630A patent/AU2007328630B2/en not_active Ceased
- 2007-12-07 MX MX2008016099A patent/MX2008016099A/es unknown
- 2007-12-07 EP EP07851323.1A patent/EP2037917B1/en not_active Not-in-force
- 2007-12-07 CN CN2007800229752A patent/CN101472587B/zh not_active Expired - Fee Related
- 2007-12-07 JP JP2009522726A patent/JP4995912B2/ja not_active Expired - Fee Related
- 2007-12-07 US US12/303,034 patent/US20100233261A1/en not_active Abandoned
- 2007-12-07 CA CA2654054A patent/CA2654054C/en not_active Expired - Fee Related
- 2007-12-07 UA UAA200814649A patent/UA92641C2/ru unknown
- 2007-12-07 ZA ZA200910116A patent/ZA200910116B/xx unknown
- 2007-12-07 ES ES07851323.1T patent/ES2522567T3/es active Active
- 2007-12-07 RU RU2008150477/15A patent/RU2401107C2/ru not_active IP Right Cessation
- 2007-12-07 WO PCT/KR2007/006352 patent/WO2008069612A1/en active Application Filing
-
2008
- 2008-11-27 ZA ZA2008/10116A patent/ZA200810116B/en unknown
- 2008-11-27 IL IL195581A patent/IL195581A/en not_active IP Right Cessation
- 2008-12-12 EC EC2008008980A patent/ECSP088980A/es unknown
- 2008-12-18 NO NO20085302A patent/NO20085302L/no not_active Application Discontinuation
-
2009
- 2009-12-17 HK HK09111875.8A patent/HK1131916A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA200910116B (en) | 2010-07-28 |
HK1131916A1 (en) | 2010-02-12 |
ZA200810116B (en) | 2010-07-28 |
US20100233261A1 (en) | 2010-09-16 |
ES2522567T3 (es) | 2014-11-17 |
CN101472587B (zh) | 2013-11-20 |
MX2008016099A (es) | 2009-01-19 |
AU2007328630B2 (en) | 2010-03-11 |
BRPI0713306A8 (pt) | 2016-06-07 |
CA2654054A1 (en) | 2008-06-12 |
ECSP088980A (es) | 2009-02-27 |
CN101472587A (zh) | 2009-07-01 |
EP2037917B1 (en) | 2014-10-08 |
IL195581A (en) | 2015-08-31 |
JP4995912B2 (ja) | 2012-08-08 |
BRPI0713306A2 (pt) | 2012-04-17 |
CA2654054C (en) | 2013-01-08 |
RU2401107C2 (ru) | 2010-10-10 |
MY144857A (en) | 2011-11-30 |
KR101247583B1 (ko) | 2013-03-26 |
KR20080052852A (ko) | 2008-06-12 |
NO20085302L (no) | 2009-06-17 |
EP2037917A4 (en) | 2010-08-04 |
AU2007328630A1 (en) | 2008-06-12 |
IL195581A0 (en) | 2009-09-01 |
WO2008069612A1 (en) | 2008-06-12 |
RU2008150477A (ru) | 2010-06-27 |
JP2009544752A (ja) | 2009-12-17 |
NZ573223A (en) | 2012-07-27 |
EP2037917A1 (en) | 2009-03-25 |
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